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JaLCDOI 10.18926/AMO/61906
FullText URL 75_2_231.pdf
Author Endo, Motochika| Yano, Shuya| Asano, Hiroaki| Takeda, Sho| Hamada, Yuki| Kondo, Yoshitaka| Kuroda, Shinji| Shigeyasu, Kunitoshi| Kikuchi, Satoru| Tanaka, Takehiro| Teraishi, Fuminori| Nishizaki, Masahiko| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Abstract Targeted therapies for malignant melanoma have improved patients’ prognoses. A primary gastrointestinal malignant melanoma is very rare, with no standard treatment strategy. We treated a 78-year-old Japanese female with advanced primary gastrointestinal melanoma of the descending colon and gallbladder. We administered a multidisciplinary treatment: surgical resection of the descending colon and gallbladder tumors, resection of the metastatic lymph nodes behind the pancreas head, and immune checkpoint antibody-blockade therapy (nivolumab) for ~4 years. PET/CT demonstrated no recurrent lesion for > 3 years. Multidisciplinary therapies (e.g., surgery, chemotherapy, radiotherapy, target therapy, and immune checkpoint antibody-blockade therapy) can successfully treat primary gastrointestinal malignant melanoma.
Keywords primary gastrointestinal melanoma laparoscopic surgery immune checkpoint antibody-blockade inhibitor
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 231
End Page 238
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953431
NAID 120007029881
JaLCDOI 10.18926/AMO/61905
FullText URL 75_2_225.pdf
Author Xue, Haowei| Furumatsu, Takayuki| Okazaki, Yuki | Hiranaka, Takaaki| Kintaka, Keisuke | Zhang, Ximing| Yoshida, Aki| Ozaki, Toshifumi|
Abstract A 65-year-old man presented with a left medial meniscus (MM) posterior root tear (PRT). Unicompartmental knee arthroplasty was performed 12 months after transtibial pullout repair of the MMPRT. Repaired MM posterior root tissue was subjected to histological analysis. Immunostaining and picrosirius red staining showed sufficient deposition of type I collagen, and hematoxylin-eosin staining using a polarized microscope showed well-aligned fiber orientation in the repaired tissue. The repaired posterior root (post-transtibial pullout repair) showed mature and well-aligned ligament-like tissue. Preserving the MM posterior root remnant to mimic the original posterior root tissue might be useful when performing pullout repair.
Keywords medial meniscus posterior root tear unicompartmental knee arthroplasty histological analysis case report
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 225
End Page 230
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953430
NAID 120007029882
JaLCDOI 10.18926/AMO/61903
FullText URL 75_2_213.pdf
Author Miyashita, Manabi| Saragai, Yousuke| Fujimoto, Tsuyoshi| Tanaka, Shouichi| Aoki, Hideki| Sato, Yumiko |
Abstract A 75-year-old Japanese man visited our hospital for further examination of liver tumors. He had a history of successful hepatitis C virus (HCV) eradication and therapy for hepatocellular carcinoma (HCC) at another hospital. Magnetic resonance imaging (MRI) revealed two tumors in the liver. He underwent anterior inferior (S5) and posterior inferior (S6) subsegmentectomy of the liver. Microscopic examination found that one tumor was HCC while the other was cholangiolocellular carcinoma (CoCC). We experienced a rare case of liver cancer with two synchronous pathologies, HCC and CoCC.
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 213
End Page 218
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953428
NAID 120007029884
JaLCDOI 10.18926/interdisciplinary/61888
Title Alternative Consideration about recognition of factors causing lack of confirmation in the nursing scene
FullText URL interdisciplinary_1_29_45.pdf
Author Zuo, Wanxin| Hyodo, Yoshimi| Tanaka, Tomoko| Gofuku, Akio|
Abstract In the work process of nurses with high risk, it is very urgent to take countermeasures against the “lack of confirmation” of the main factors. Therefore, the purpose of this study is to clarify the details of the factors leading to the lack of confirmation, grasp the number of near misses, and to explore what kind of factors the individual characteristics of the nurse who acts as a stopper. We recruited 500 nurses on the Web and asked about the frequency of near misses due to lack of confirmation, the awareness of the causes of lack of confirmation, self-evaluation of stoppers, and the reasons why near misses did not lead to accidents. As a result, three factors were extracted regarding the recognition of the factors of lack of confirmation: "lack of consciousness", "inability to concentrate", and "lack of knowledge / experience". Three factors were extracted for self-evaluation of stopper characteristics: "awareness," "verification," and "cautiousness". In order to reduce the lack of confirmation, it is necessary to secure and allocate appropriate personnel and create an environment where treatment can be concentrated. Nurses should also raise knowledge and the awareness of the importance of confirmation. In addition, it is necessary to improve the clinical judgment of new nurses in order to prevent near misses. And it is thought that new nurses will become more confident by accumulating experience and affirming their abilities from their superiors, seniors and colleagues.
Keywords lack of confirmation stoppers nurse
Publication Title Interdisciplinary Science
Published Date 2021-03-31
Volume volume1
Start Page 29
End Page 45
ISSN 2436-3227
language Japanese
File Version publisher
NAID 120007029897
JaLCDOI 10.18926/AMO/61881
FullText URL 75_2_147.pdf
Author Xue, Haowei | Furumatsu, Takayuki| Okazaki, Yuki | Hiranaka, Takaaki | Kintaka, Keisuke | Fujii, Masataka | Zhang, Ximing| Ozaki, Toshifumi|
Abstract Medial meniscus posterior root tears (MMPRTs) have recently attracted considerable interest in orthopedics. To date, no in vivo human study has investigated suture translation changes in repaired MMPRTs with different degrees of knee flexion. This study examined suture translation at various degrees of knee flexion in 30 patients undergoing medial meniscus posterior root repair using the modified Mason-Allen suture technique between August 2016 and September 2017. Intraoperatively, sutures were provisionally fixed to an isometric positioner at the tibial site of the desired meniscal attachment, and the suture translation was measured at 0°, 30°, 60°, and 90° of knee flexion. The results showed significant increases in mean suture translation at the knee flexion positions from 0° to 30°, 30° to 60°, and 60° to 90° (p<0.01 for all). Our findings indicate that surgeons should carefully assess the degree of knee flexion at the moment when the meniscus is refixed by surgical sutures.
Keywords medial meniscus posterior root tear suture translation knee flexion arthroscopic repair
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 147
End Page 152
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953421
NAID 120007029902
JaLCDOI 10.18926/AMO/61879
FullText URL 75_2_133.pdf
Author Hashida, Shinsuke| Tanaka, Norimitsu| Takahashi, Yuta| Onoda, Yuji| Colvin, Hugh Shunsuke| Ohashi, Ryuichiro| Okamoto, Kunio |
Abstract As the nanoparticle albumin-bound paclitaxel (nab-PTX) is free of ethanol and premedication, the duration of administration is shorter and patients can drive themselves to and from the hospital. In the 2018 Japanese gastric cancer treatment guidelines, ramucirumab (RAM) plus weekly nab-PTX is conditionally recommended for previously treated patients with advanced gastric cancer. Here, we retrospectively analysed the efficacy and safety of RAM+nab-PTX for such patients in community hospitals. From January 2018 to December 2019, 43 patients with metastatic and recurrent gastric cancer received RAM+nab-PTX treatment. Six patients (13.9%) were older than 80 years and 9 patients (20.9%) showed ECOG-PS 2. Progression-free survival (PFS), overall survival (OS), overall response rate (ORR), disease control rate (DCR), and adverse events (AEs) were reviewed retrospectively. Median PFS was 114 days (95% confidence interval [CI]: 84-190) and median OS was 297 days (95% CI: 180-398). ORR and DCR were 32.4% and 72.2%, respectively. The incidence rates of ≥grade 3 neutropenia and febrile neutropenia were 53.5% and 2.3%, respectively. No treatment-related deaths occurred. RAM plus nab-PTX combination therapy demonstrated manageable toxicity even patients who were elderly or had an ECOG-PS 2. This treatment is useful in community hospital settings.
Keywords gastric cancer ramucirumab nab-paclitaxel
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 133
End Page 138
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953419
NAID 120007029904
JaLCDOI 10.18926/AMO/61877
FullText URL 75_2_115.pdf
Author Hitomi, Nishizaki| Yoshinari, Morimoto| Yamada, Shin-ichi| Kurita, Hiroshi| Tanaka, Akira| Yamaguchi, Akira| Miyata, Masaru| Yoshikawa, Hiromasa | Yanamoto, Souichi| Imai, Yutaka|
Abstract The aim of this study was to investigate the awareness and experience, among dental practitioners, of adverse events resulting from dental treatment of patients undergoing therapy with drugs that affect the immune system [angiogenesis inhibitors, biological agents, immunosuppressants, and disease-modifying anti-rheumatic drugs (DMARDs)]. For this purpose, a nationwide questionnaire survey was conducted. Questionnaires were sent to 2,050 dentists, of which 206 (10.1%) were completed and returned. The results showed that most dentists were aware of complications associated with dental treatment of patients treated with drugs that affect the immune system, and about half had actually experienced such complications. Delayed wound healing, osteonecrosis of the jaw (ONJ), and postoperative infections were reported. Whereas approximately 50% of dentists did not discontinue the drugs during dental treatment, about 18% did. During temporary drug discontinuation, some patients experienced aggravation of the primary disease, such as worsening of rheumatism, growth of tumors, and rejection reactions of transplanted organs. As for medical cooperation, only less than half of the dentists were asked for oral hygiene management by a physician prior to starting the drug treatment. Prospective studies are needed because evidence for dental treatments in patients treated with these drugs remains limited.
Keywords angiogenesis inhibitor biological agent disease-modifying antirheumatic drug (DMARD) immunosuppressant medication-related osteonecrosis of the jaw (MRONJ)
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-04
Volume volume75
Issue issue2
Publisher Okayama University Medical School
Start Page 115
End Page 123
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33953417
NAID 120007029906
FullText URL fulltext20210421_1.pdf figure20210421_1.pdf
Author Hutami, Islamy Rahma| Izawa, Takashi| Khurel‐Ochir, Tsendsuren| Sakamaki, Takuma| Iwasa, Akihiko| Tomita, Shuhei| Tanaka, Eiji|
Keywords HIF-1α S1P receptor hypoxia wound healing M1/M2 macrophage DMOG
Note This is an Accepted Manuscript of an article published by Wiley. This is the peer reviewed version of the following article: [Hutami, IR, Izawa, T, Khurel-Ochir, T, et al. HIF-1α controls palatal wound healing by regulating macrophage motility via S1P/S1P1 signaling axis. Oral Dis. 2021; 00: 1– 13. https://doi.org/10.1111/odi.13856], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.|
Published Date 2021-4
Publication Title Oral Diseases
Volume volume28
Issue issue4
Publisher Wiley
Start Page 1157
End Page 1169
ISSN 1354-523X
NCID AA11044105
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 33759275
DOI 10.1111/odi.13856
Web of Science KeyUT 000635801500001
Related Url isVersionOf https://doi.org/10.1111/odi.13856
FullText URL fulltext.pdf
Author Satomi, Takuya| Kawano, Seiji| Inaba, Tomoki| Nakagawa, Masahiro| Mouri, Hirokazu| Yoshioka, Masao| Tanaka, Shoichi| Toyokawa, Tatsuya| Kobayashi, Sayo| Tanaka, Takehiro| Kanzaki, Hiromitsu| Iwamuro, Masaya| Kawahara, Yoshiro| Okada, Hiroyuki|
Keywords Endoscopic submucosal dissection Gastric tube Gastric cancer Eso-phagectomy Multicenter study Retrospective study
Published Date 2021-03-21
Publication Title World Journal of Gastroenterology
Volume volume27
Issue issue11
Publisher Baishideng Publishing Group Inc.
Start Page 1043
End Page 1054
ISSN 1007-9327
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version publisher
PubMed ID 33776371
DOI 10.3748/wjg.v27.i11.1043
NAID 120007027578
Web of Science KeyUT 000635258600004
Related Url isVersionOf https://doi.org/10.3748/wjg.v27.i11.1043
FullText URL fulltext20210416.pdf
Author Yamashita, Koichiro| Tanaka, Tenu| Matsuo, Toshihiko| Uchida, Tetsuya|
Keywords retinal prosthesis photoelectric dye polyethylene film retinitis pigmentosa durability
Note This is an Accepted Manuscript of an article published by IOP| This fulltext is available in March 2022|
Published Date 2021-3-8
Publication Title Biomedical Materials
Volume volume16
Issue issue4
Publisher IOP Publishing
Start Page 045001
ISSN 1748-6041
NCID AA12157402
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 33607636
DOI 10.1088/1748-605x/abe809
Web of Science KeyUT 000626891900001
Related Url isVersionOf https://doi.org/10.1088/1748-605x/abe809
FullText URL fulltext20210413_1.pdf
Author Tanaka, Takashi| Kawashima, Akira| Marukawa, Yohei| Kitayama, Takahiro| Masaoka, Yoshihisa| Kojima, Katsuhide| Iguchi, Toshihiro| Hiraki, Takao| Kanazawa, Susumu|
Keywords Hereditary renal tumor syndrome Von Hippel–Lindau disease Birt–Hogg–Dubé syndrome Tuberous sclerosis complex Hereditary leiomyomatosis and renal cell carcinoma syndrome
Note This is an Accepted Manuscript of an article published by Springer. This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s11604-021-01109-5|
Published Date 2021-3-23
Publication Title Japanese Journal of Radiology
Volume volume39
Publisher Springer Science and Business Media LLC
Start Page 619
End Page 632
ISSN 1867-1071
NCID AA12375935
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders ©Japan Radiological Society 2021
File Version author
PubMed ID 33759057
DOI 10.1007/s11604-021-01109-5
NAID 130008000092
Web of Science KeyUT 000631734600001
Related Url isVersionOf https://doi.org/10.1007/s11604-021-01109-5
FullText URL fulltext.pdf
Author Tanaka, Takehiro| Nishida, Kenji| Iwamuro, Masaya| Kikuchi, Satoru| Yoshino, Tadashi|
Published Date 2021-02-26
Publication Title Case reports in gastrointestinal medicine
Volume volume2021
Publisher HINDAWI LTD
Start Page 6617370
ISSN 2090-6528
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Takehiro Tanaka et al.
File Version publisher
PubMed ID 33728073
DOI 10.1155/2021/6617370
Web of Science KeyUT 000627132200002
Related Url isVersionOf https://doi.org/10.1155/2021/6617370
FullText URL fulltext20210506_1.pdf
Author Ninomiya, Kiichiro| Teraoka, Shunsuke| Zenke, Yoshitaka| Kenmotsu, Hirotsugu| Nakamura, Yukiko| Okuma, Yusuke| Tamiya, Akihiro| Nosaki, Kaname| Morise, Masahiro| Aokage, Keiju| Oya, Yuko| Kozuki, Toshiyuki| Sakamoto, Tomohiro| Tanaka, Kentaro| Tanaka, Hisashi| Tanizaki, Junko| Miura, Satoru| Mizutani, Hideaki| Miyauchi, Eisaku| Yamaguchi, Ou| Ebi, Noriyuki| Goto, Yasushi| Sasaki, Takaaki| Daga, Haruko| Morita, Satoshi| Yamanaka, Takeharu| Amano, Shinsuke| Hasegawa, Kazuo| Imamura, Chiyo K.| Suzuki, Kenichi| Nakajima, Kazuko| Nishimoto, Hitomi| Oizumi, Satoshi| Hida, Toyoaki| Hotta, Katsuyuki| Takiguchi, Yuichi|
Keywords Non–small cell lung cancer Epidermal growth factor receptor Systematic review Guidelines
Published Date 2021-01-31
Publication Title JTO Clinical and Research Reports
Volume volume2
Issue issue1
Publisher Elsevier
Start Page 100107
ISSN 26663643
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
DOI 10.1016/j.jtocrr.2020.100107
NAID 120007032762
Related Url isVersionOf https://doi.org/10.1016/j.jtocrr.2020.100107
FullText URL fulltext.pdf
Author Matsumoto, Masakazu| Yagasaki, Takuma| Tanaka, Hideki|
Note This fulltext is available in March 2022.|
Published Date 2021-03-01
Publication Title The Journal of Chemical Physics
Volume volume154
Issue issue9
Publisher AIP Publishing
Start Page 094502
ISSN 0021-9606
NCID AA00694991
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version publisher
PubMed ID 33685157
DOI 10.1063/5.0044300
Web of Science KeyUT 000630524700002
Related Url isVersionOf https://doi.org/10.1063/5.0044300
FullText URL JCEH_61_1_10.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro| Sato, Yasuharu| Kataoka, Hitomi| Uka, Mayu| Ennishi, Daisuke| Yano, Tomofumi|
Keywords IgG4-related disease lacrimal gland serum IgG4 prednisolone extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)
Published Date 2021
Publication Title Journal of Clinical and Experimental Hematopathology
Volume volume61
Issue issue1
Publisher Japanese Society for Lymphoreticular Tissue Research
Start Page 10
End Page 20
ISSN 1346-4280
NCID AA11556796
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by The Japanese Society for Lymphoreticular Tissue Research
File Version publisher
PubMed ID 33731547
DOI 10.3960/jslrt.20048
Related Url isVersionOf https://doi.org/10.3960/jslrt.20048
FullText URL fulltext.pdf
Author Yoshino, Tadashi| Tanaka, Takehiro| Sato, Yasuharu|
Keywords chronic lymphocytic leukemia/small lymphocytic lymphoma differential diagnosis indolent lymphoma
Published Date 2020
Publication Title Journal of Clinical and Experimental Hematopathology
Volume volume60
Issue issue4
Publisher Japanese Society for Lymphoreticular Tissue Research
Start Page 124
End Page 129
ISSN 1346-4280
NCID AA11556796
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 by The Japanese Society for Lymphoreticular Tissue Research
File Version publisher
PubMed ID 32249238
DOI 10.3960/jslrt.19041
Web of Science KeyUT 000599137300002
Related Url isVersionOf https://doi.org/10.3960/jslrt.19041
FullText URL kokugo_35_030_039.pdf
Author 田中 智生|
Publication Title 岡山大学国語研究
Published Date 2021-03-20
Volume volume35
Start Page 30
End Page 39
ISSN 2189-5414
language Japanese
File Version publisher
JaLCDOI 10.18926/bgeou/61465
FullText URL bgeou_176_037_046.pdf
Author NISHIYAMA, Osamu| WAKADA, Mika| TANAKA, Osanori|
Abstract This study stands on long-term longitudinal research of 12 years from the training stage to the initial and middle terms. The study traced the changes in childcare worker identities and clarified the relationship between long-term changes in childcare worker identities and autobiographical memories. To be more specific, the study continuously applied the Multidimensional Ego Identity Scale (Tani, 2001a) to the training school graduation period, the initial term, and the transition from initial form to mid-career. Also, the study looked back on the past from the mid-career period. The childcare worker was subsequently asked for descriptions of childcare episodes as autobiographical memories. As a result, it turned out that there were four patterns of changes in the identities of childcare workers: “descending group,” “ascending group,” “low sustaining group,” and “high sustaining group.” These change patterns appeared to match the descriptions of the corresponding autobiographical memories. The study sorted out each group using extracted keywords and the like.
Publication Title Bulletin of Graduate School of Education, Okayama University
Published Date 2021-02-24
Volume volume176
Start Page 37
End Page 46
ISSN 1883-2423
language Japanese
File Version publisher
NAID 120006980460
FullText URL fulltext.pdf
Author Kataoka, Noriyuki| Tanaka, Masashi| Hosoda, Wataru| Taniguchi, Takumi| Fujimori, Shin-ichi| Wakita, Takanori| Muraoka, Yuji| Yokoya, Takayoshi|
Note This fulltext is available in Oct. 2021.|
Published Date 2020-10-16
Publication Title Journal of Physics: Condensed Matter
Volume volume33
Issue issue3
Publisher IOP Publishing
Start Page 035501
ISSN 0953-8984
NCID AA10672168
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 32977314
DOI 10.1088/1361-648x/abbbc3
Web of Science KeyUT 000581660000001
Related Url isVersionOf https://doi.org/10.1088/1361-648X/abbbc3
JaLCDOI 10.18926/AMO/61433
FullText URL 75_1_45.pdf
Author Otsuka, Hiroaki| Miyoshi, Toru| Ejiri, Kentaro| Kohno, Kunihisa| Nakahama, Makoto| Doi, Masayuki| Munemasa, Mitsuru| Murakami, Masaaki| Nakamura, Kazufumi| Ito, Hiroshi|
Abstract Remote ischemic preconditioning (RIPC) is a promising strategy for protecting against ischemic reperfusion injury. This study is a secondary analysis of a randomized study that aimed to evaluate the effect of RIPC on the early increase in serum creatinine (SCr) following percutaneous coronary intervention (PCI), which is associ-ated with contrast-induced acute kidney injury. Patients with stable angina undergoing elective PCI were assigned to control, RIPC, and continuous infusion of nicorandil (nicorandil) groups. The endpoint of this study was the incidence of the early increase in SCr, a predictor of contrast-induced acute kidney injury, which was defined as either a > 20% or absolute increase by 0.3 mg/dl of SCr levels after 24 h of PCI. This study included 220 patients for whom a dataset of SCr values was available. The incidence of the early increase in SCr was significantly lower in the RIPC than in the control (1.3% vs 10.8%, p = 0.03) group, but was not significantly different between the nicorandil and control groups. In multivariate analysis, RIPC remained a significant fac-tor associated with a reduction in the incidence of early increase in SCr. RIPC reduces the incidence of early increase in SCr in patients with stable angina following elective PCI.
Keywords remote ischemic preconditioning stable angina serum creatinine acute kidney injury
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-02
Volume volume75
Issue issue1
Publisher Okayama University Medical School
Start Page 45
End Page 53
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33649613