The electrical impedance of a living tissue reflects its cell construction and physiological activity. For this purpose we developed an automatic sensing device of electrical tissue characteristics. The system is composed of a part measuring impedance at multifrequency points and a part analyzing parameters of dispersion of bioelectrical impedance, impedances are measured at eight frequency points of 1 kHz-500 kHz. The parameters for Cole-Cole arc's law are determined automatically by a personal computer program
en-copyright= kn-copyright= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HaradaHiroshi en-aut-sei=Harada en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YasuharaKiyotaka en-aut-sei=Yasuhara en-aut-mei=Kiyotaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=biological techniques kn-keyword=biological techniques en-keyword=cellular biophysics kn-keyword=cellular biophysics en-keyword=computerised instrumentation kn-keyword=computerised instrumentation en-keyword=electric impedance kn-keyword=electric impedance en-keyword=measurement kn-keyword=measurement en-keyword=electric sensing devices kn-keyword=electric sensing devices END start-ver=1.4 cd-journal=joma no-vol=47 cd-vols= no-issue=1 article-no= start-page=2 end-page=9 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20052 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Convergence acceleration and accuracy improvement in power bus impedance calculation with a fast algorithm using cavity modes en-subtitle= kn-subtitle= en-abstract= kn-abstract=Based on the cavity-mode model, we have developed a fast algorithm for calculating power bus impedance in multilayer printed circuit boards. The fast algorithm is based on a closed-form expression for the impedance Z matrix of a rectangular power bus structure; this expression was obtained by reducing the original double infinite series into a single infinite series under an approximation. The convergence of the single series is further accelerated analytically. The accelerated single summation enables much faster computation, since use of only a few terms is enough to obtain good accuracy. In addition, we propose two ways to compensate for the error due to the approximation involved in the process of reducing the double series to the single series, and have demonstrated that these two techniques are almost equivalent. en-copyright= kn-copyright= en-aut-name=WangZhi Liang en-aut-sei=Wang en-aut-mei=Zhi Liang kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=WadaOsami en-aut-sei=Wada en-aut-mei=Osami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ToyotaYoshitaka en-aut-sei=Toyota en-aut-mei=Yoshitaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KogaRyuji en-aut-sei=Koga en-aut-mei=Ryuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=Cavity-mode model kn-keyword=Cavity-mode model en-keyword=closed-form expression for fast calculation kn-keyword=closed-form expression for fast calculation en-keyword=power bus impedance kn-keyword=power bus impedance en-keyword=power bus kn-keyword=power bus en-keyword=resonance kn-keyword=resonance END start-ver=1.4 cd-journal=joma no-vol=4 cd-vols= no-issue= article-no= start-page=1449 end-page=1450 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=199611 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Estimation of muscle fatigue by using EMG and muscle stiffness en-subtitle= kn-subtitle= en-abstract= kn-abstract=This study aims at the measurement and estimation of muscle fatigue. Viscoelasticity is calculated from the biomechanical impedance spectrum and EMG is measured. When isometric and isotonic muscle fatigue are created in the forearm, elasticity, viscosity and IEMG increase, and MNF decreases. Each variable change rate, however, is different in order to estimate muscle fatigue synthetically, PCA is calculated by using viscoelasticity and EMG. As a result, it is suggested that the 1st component expresses a change in muscle stiffness and the 2nd component expresses objective fatigue. The slope of the approximation line seems to correspond to the degree of muscle fatigue
en-copyright= kn-copyright= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=Okayama University en-keyword=biomechanics kn-keyword=biomechanics en-keyword=electromyography kn-keyword=electromyography en-keyword=medical signal processing kn-keyword=medical signal processing en-keyword=muscle kn-keyword=muscle en-keyword=viscoelasticity kn-keyword=viscoelasticity END start-ver=1.4 cd-journal=joma no-vol=133 cd-vols= no-issue=2 article-no= start-page=538 end-page=542 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080812 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Analysis of response mechanism of a proton-pumping gate FET hydrogen gas sensor in air en-subtitle= kn-subtitle= en-abstract= kn-abstract=Two different types of hydrogen response signals (DC and AC) of a proton-pumping gate FET with triple layer gate structure (Pd/proton conducting polymer/Pt) were obtained. The proton-pumping gate FET showed good selectivity against other gases (CH4, C2H6, NH3, and O2). For practical use, the hydrogen response characteristics of the proton-pumping gate FET were investigated in air (a gaseous mixture of oxygen and nitrogen). The proton-pumping gate FET showed different hydrogen response characteristics in nitrogen as well as in air, despite the lack of oxygen interference independently. To clarify the response mechanism of the proton-pumping gate FET, a hydrogen response measurement was performed, using a gas flow system and electrochemical impedance spectroscopy. Consequently, the difference in response between nitrogen and air was found to be due to the hydrogen dissociation reaction and the interference with the proton transfer caused by the adsorbed oxygen on the upper Pd gate electrode
en-copyright= kn-copyright= en-aut-name=YamaguchiTomiharu en-aut-sei=Yamaguchi en-aut-mei=Tomiharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakisawaMasanori en-aut-sei=Takisawa en-aut-mei=Masanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KiwaToshihiko en-aut-sei=Kiwa en-aut-mei=Toshihiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamadaHironobu en-aut-sei=Yamada en-aut-mei=Hironobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TsukadaKeiji en-aut-sei=Tsukada en-aut-mei=Keiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Department of Electrical and Electronic Engineering, Okayama University affil-num=4 en-affil= kn-affil=Department of Electrical and Electronic Engineering, Okayama University affil-num=5 en-affil= kn-affil=Department of Electrical and Electronic Engineering, Okayama University en-keyword=Field effect transistor (FET) kn-keyword=Field effect transistor (FET) en-keyword=Hydrogen sensor kn-keyword=Hydrogen sensor en-keyword=Proton-pumping gate kn-keyword=Proton-pumping gate en-keyword=Oxygen kn-keyword=Oxygen en-keyword=Electrochemical impedance spectroscopy (EIS) kn-keyword=Electrochemical impedance spectroscopy (EIS) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=304 end-page=307 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20063 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A LECCS model parameter optimization algorithm for EMC designs of IC/LSI systems en-subtitle= kn-subtitle= en-abstract= kn-abstract=<p>In this paper, we propose a parameter optimization algorithm for EMC macro-modeling of IC/LSI power currents called the LECCS (linear equivalent circuit and current source) model. The unnecessary electro-magnetic wave from a digital electronics device may cause the electromagnetic interference (EMI) to other apparatus. Thus, its reduction has been regarded as one of the highest priority issues in digital electronics device designs. In order to accurately simulate high-frequency currents from power-supply sources that are the primary sources of EMI, the LECCS model has been proposed as a linear macromodel of a power-supply circuit. A LECCS model consists of multiple RLC-series circuits in parallel to represent the equivalent circuit between the voltage source and the ground. Given a set of measured impedances at various frequencies, our proposed algorithm first finds the number of RLC-series circuits corresponding to the number of valleys. Then, it searches optimal values of RLC parameters by a local search method. The effectiveness of our algorithm is verified through applications to a real system, where the accuracy and the required processing time by our algorithm are compared with the conventional method.</p>
en-copyright= kn-copyright= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NomuraYohei en-aut-sei=Nomura en-aut-mei=Yohei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KawashimaJun en-aut-sei=Kawashima en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MinamisawaYuichiro en-aut-sei=Minamisawa en-aut-mei=Yuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=WadaOsami en-aut-sei=Wada en-aut-mei=Osami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=kyoto University en-keyword=RLC circuits kn-keyword=RLC circuits en-keyword=electromagnetic compatibility kn-keyword=electromagnetic compatibility en-keyword=electromagnetic interference kn-keyword=electromagnetic interference en-keyword=equivalent circuits kn-keyword=equivalent circuits en-keyword=integrated circuit design kn-keyword=integrated circuit design en-keyword=large scale integration kn-keyword=large scale integration en-keyword=linear network analysis kn-keyword=linear network analysis END start-ver=1.4 cd-journal=joma no-vol=45 cd-vols= no-issue= article-no= start-page=483 end-page=487 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19964 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Instantaneous measurement of electrical parameters in a palm during electrodermal activity en-subtitle= kn-subtitle= en-abstract= kn-abstract=The determination of impedance can be performed by means of a frequency-domain analysis or a time-domain analysis. The latter has the advantage of being able to measure instantaneously all the frequency characteristics of impedance. The method is hence well suited to obtain the biological impedance which changes with time. An instantaneous method of measuring skin impedance, by using time-domain analysis has thus been developed. The fast Fourier transform (FFT) of the step response for current to the skin can determine the palm impedance. This method can carry out the determination of the parameters of the palm skin impedance during a galvanic skin reflex (GSR), which is impossible by means of frequency-domain analysis
en-copyright= kn-copyright= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IsshikiHiromi en-aut-sei=Isshiki en-aut-mei=Hiromi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Takuma National College of Technology affil-num=3 en-affil= kn-affil=Okayama University en-keyword=bioelectric phenomena kn-keyword=bioelectric phenomena en-keyword=electric impedance measurement kn-keyword=electric impedance measurement en-keyword=fast Fourier transforms kn-keyword=fast Fourier transforms en-keyword=medical kn-keyword=medical en-keyword=signal processing kn-keyword=signal processing en-keyword=signal detection kn-keyword=signal detection en-keyword=skin kn-keyword=skin en-keyword=step response kn-keyword=step response en-keyword=time-domain analysis kn-keyword=time-domain analysis en-keyword=transient kn-keyword=transient en-keyword=response kn-keyword=response en-keyword=waveform analysis kn-keyword=waveform analysis END start-ver=1.4 cd-journal=joma no-vol=44 cd-vols= no-issue=3 article-no= start-page=729 end-page=732 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19956 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Automatic sensing device of electrical characteristics of living trees en-subtitle= kn-subtitle= en-abstract= kn-abstract=The electrical impedance of a living tissue reflects its cell construction and physiological activity. For this purpose we developed an automatic sensing device of electrical tissue characteristics. The system is composed of a part measuring impedance at multifrequency points and a part analyzing parameters of dispersion of bioelectrical impedance, impedances are measured at eight frequency points of 1 kHz-500 kHz. The parameters for Cole-Cole arc's law are determined automatically by a personal computer program
en-copyright= kn-copyright= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HaradaHiroshi en-aut-sei=Harada en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YasuharaKiyotaka en-aut-sei=Yasuhara en-aut-mei=Kiyotaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Takamatsu National College of Technology en-keyword=biological techniques kn-keyword=biological techniques en-keyword=cellular biophysics kn-keyword=cellular biophysics en-keyword=computerised instrumentation kn-keyword=computerised instrumentation en-keyword=electric impedance kn-keyword=electric impedance en-keyword=measurement kn-keyword=measurement en-keyword=electric sensing devices kn-keyword=electric sensing devices END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=282 end-page=283 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=200310 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evaluating object and region of concentric electrode in bio-electrical impedance measurement en-subtitle= kn-subtitle= en-abstract= kn-abstract=Concentric electrode is easy to use and used widely for measuring bio-electrical impedance. But, its evaluating region was not investigated in detail. Then, the characteristics of concentric electrode were studied from various points of view. In case of use without electrode paste, impedance is determined with the contacting condition between electrode and skin surface over all frequency range. In case of use with electrode past, impedance is composed of stratum corneum in the frequency range of 20 Hz-1 kHz and is mainly composed of subcutaneous tissue in the range of 200 kHz-1 MHz. In the high frequency range, evaluating region of concentric electrode is the area less than the radius or the gap of center electrode. en-copyright= kn-copyright= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ShiraiKiyoko en-aut-sei=Shirai en-aut-mei=Kiyoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=GodaNoriko en-aut-sei=Goda en-aut-mei=Noriko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KusuharaToshimasa en-aut-sei=Kusuhara en-aut-mei=Toshimasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OkudaHiroyuki en-aut-sei=Okuda en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Faculty of Health Sciences, Okayama University Medical School affil-num=2 en-affil= kn-affil=Faculty of Health Sciences, Okayama University Medical School affil-num=3 en-affil= kn-affil=Faculty of Health Sciences, Okayama University Medical School affil-num=4 en-affil= kn-affil=Faculty of Health Sciences, Okayama University Medical School affil-num=5 en-affil= kn-affil=Faculty of Health Sciences, Okayama University Medical School affil-num=6 en-affil= kn-affil=Faculty of Health Sciences, Okayama University Medical School en-keyword=Bio-electrieal impedance kn-keyword=Bio-electrieal impedance en-keyword=skin impedance kn-keyword=skin impedance en-keyword=concentric electrode kn-keyword=concentric electrode en-keyword=evaluating kn-keyword=evaluating en-keyword=region kn-keyword=region END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=73 end-page=76 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=200311 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Analysis of resonance characteristics of a power bus with rectangle and triangle elements in multilayer PCBs en-subtitle= kn-subtitle= en-abstract= kn-abstract=One of the major sources of radiated EMI is attributed to power bus resonance in a printed circuit board (PCB). A fast algorithm, combined with the segmentation method, is applied for calculating resonance characteristics of a power bus whose pattern consists of several segments of rectangles and/or right-angled triangles. Good agreement between the calculated and measured results demonstrates the usefulness and accuracy of the fast algorithm and the segmentation method.
en-copyright= kn-copyright= en-aut-name=WangZhi Liang en-aut-sei=Wang en-aut-mei=Zhi Liang kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=WadaOsami en-aut-sei=Wada en-aut-mei=Osami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ToyotaYoshitaka en-aut-sei=Toyota en-aut-mei=Yoshitaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KogaRyuji en-aut-sei=Koga en-aut-mei=Ryuji kn-aut-name=古賀隆治 kn-aut-sei=古賀 kn-aut-mei=隆治 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=S-matrix theory kn-keyword=S-matrix theory en-keyword=electromagnetic interference kn-keyword=electromagnetic interference en-keyword=impedance matrix kn-keyword=impedance matrix en-keyword=printed circuits kn-keyword=printed circuits en-keyword=resonance kn-keyword=resonance END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=304 end-page=307 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20063 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A LECCS model parameter optimization algorithm for EMC designs of IC/LSI systems en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this paper, we propose a parameter optimization algorithm for EMC macro-modeling of IC/LSI power currents called the LECCS (linear equivalent circuit and current source) model. The unnecessary electro-magnetic wave from a digital electronics device may cause the electromagnetic interference (EMI) to other apparatus. Thus, its reduction has been regarded as one of the highest priority issues in digital electronics device designs. In order to accurately simulate high-frequency currents from power-supply sources that are the primary sources of EMI, the LECCS model has been proposed as a linear macromodel of a power-supply circuit. A LECCS model consists of multiple RLC-series circuits in parallel to represent the equivalent circuit between the voltage source and the ground. Given a set of measured impedances at various frequencies, our proposed algorithm first finds the number of RLC-series circuits corresponding to the number of valleys. Then, it searches optimal values of RLC parameters by a local search method. The effectiveness of our algorithm is verified through applications to a real system, where the accuracy and the required processing time by our algorithm are compared with the conventional method.
en-copyright= kn-copyright= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NomuraYohei en-aut-sei=Nomura en-aut-mei=Yohei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KawashimaJun en-aut-sei=Kawashima en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MinamisawaYuichiro en-aut-sei=Minamisawa en-aut-mei=Yuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=WadaOsami en-aut-sei=Wada en-aut-mei=Osami kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Kyoto University en-keyword=RLC circuits kn-keyword=RLC circuits en-keyword=electromagnetic compatibility kn-keyword=electromagnetic compatibility en-keyword=electromagnetic interference kn-keyword=electromagnetic interference en-keyword=equivalent circuits kn-keyword=equivalent circuits en-keyword=integrated circuit design kn-keyword=integrated circuit design en-keyword=large scale integration kn-keyword=large scale integration en-keyword=linear network analysis kn-keyword=linear network analysis END start-ver=1.4 cd-journal=joma no-vol=45 cd-vols= no-issue=2 article-no= start-page=483 end-page=487 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19964 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Instantaneous measurement of electrical parameters in a palm during electrodermal activity en-subtitle= kn-subtitle= en-abstract= kn-abstract=The determination of impedance can be performed by means of a frequency-domain analysis or a time-domain analysis. The latter has the advantage of being able to measure instantaneously all the frequency characteristics of impedance. The method is hence well suited to obtain the biological impedance which changes with time. An instantaneous method of measuring skin impedance, by using time-domain analysis has thus been developed. The fast Fourier transform (FFT) of the step response for current to the skin can determine the palm impedance. This method can carry out the determination of the parameters of the palm skin impedance during a galvanic skin reflex (GSR), which is impossible by means of frequency-domain analysis
en-copyright= kn-copyright= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IsshikiHiromi en-aut-sei=Isshiki en-aut-mei=Hiromi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Takuma National College of Technology affil-num=3 en-affil= kn-affil=Okayama University en-keyword=bioelectric phenomena kn-keyword=bioelectric phenomena en-keyword=electric impedance measurement kn-keyword=electric impedance measurement en-keyword=fast Fourier transforms kn-keyword=fast Fourier transforms en-keyword=medical kn-keyword=medical en-keyword=signal processing kn-keyword=signal processing en-keyword=signal detection kn-keyword=signal detection en-keyword=skin kn-keyword=skin en-keyword=step response kn-keyword=step response en-keyword=time-domain analysis kn-keyword=time-domain analysis en-keyword=transient kn-keyword=transient en-keyword=response kn-keyword=response en-keyword=waveform analysis kn-keyword=waveform analysis END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=556 end-page=561 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19915 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Portable system for measuring biomechanical properties en-subtitle= kn-subtitle= en-abstract= kn-abstract=A portable system has been developed for measuring biomechanical impedance on the skin surface. The measurement system comprises a measuring probe and a measuring device. The probe is of the pen-type. The device includes a random noise source, amplifiers, an A/D converter, a microcomputer, a liquid crystal display and a floppy disk unit. The biomechanical impedances on the skin surface are measured and the skin viscoelasticity are obtained. SI (stiffness index) is proposed as the new index of skin stiffness. The coefficient of correlation between SI and palpation scores is 0.797
en-copyright= kn-copyright= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IrieTakashi en-aut-sei=Irie en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HaoSun Yong en-aut-sei=Hao en-aut-mei=Sun Yong kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamamotoTatsuma en-aut-sei=Yamamoto en-aut-mei=Tatsuma kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=biomechanics kn-keyword=biomechanics en-keyword=biomedical measurement kn-keyword=biomedical measurement en-keyword=electric sensing devices kn-keyword=electric sensing devices en-keyword=mechanical variables measurement kn-keyword=mechanical variables measurement en-keyword=portable instruments kn-keyword=portable instruments en-keyword=probes kn-keyword=probes en-keyword=skin kn-keyword=skin END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=2302 end-page=2307 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20054 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Development of Wrist Rehabilitation Equipment Using Pneumatic Parallel Manipulator en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this study, we aim at developing a mechanical device to support humans rehabilitation motion of their wrist joint instead of or to help a physical therapist. Pneumatic parallel manipulator is introduced as the mechanical equipment from a view that pneumatic actuators bring minute force control property owing to the air compressibility and parallel manipulator’s feature of multiple degrees of freedom is suitable for a complex motion of human wrist joint. Impedance control system is introduced to realize several rehabilitation modes. The validity of the proposed system is confirmed through some experiments.
en-copyright= kn-copyright= en-aut-name=TakaiwaMasahiro en-aut-sei=Takaiwa en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NoritsuguToshiro en-aut-sei=Noritsugu en-aut-mei=Toshiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University en-keyword=Human Wrist joint kn-keyword=Human Wrist joint en-keyword=Parallel Manipulator kn-keyword=Parallel Manipulator en-keyword=Pneumatic servo system kn-keyword=Pneumatic servo system en-keyword=Rehabilitation kn-keyword=Rehabilitation END start-ver=1.4 cd-journal=joma no-vol=1 cd-vols= no-issue= article-no= start-page=231 end-page=234 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19985 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Consideration of conditions required for multi-channel simultaneous bioimpedance measurement en-subtitle= kn-subtitle= en-abstract= kn-abstract=Impedance techniques have been widely applied to the biomedical engineering field. In order to obtain definite results from bioimpedance, multi-channel measurement is effective. A linearity of biological tissue and fundamental technical parameters for the instrument must be confirmed. In this study, the fundamental conditions have been investigated for multi-channel bioimpedance measurement and the condition of measurement for biological tissue has been confirmed. The differences of every measurement frequency should be appropriate to 1 kHz and it has been shown that the linearity of biological tissue is maintained. Based on these results, a two-channel bioimpedance measurement instrument has been constructed
en-copyright= kn-copyright= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KusuharaToshimasa en-aut-sei=Kusuhara en-aut-mei=Toshimasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AdliMr. en-aut-sei=Adli en-aut-mei=Mr. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=bioelectric phenomena kn-keyword=bioelectric phenomena en-keyword=biomedical measurement kn-keyword=biomedical measurement en-keyword=electric impedance measurement kn-keyword=electric impedance measurement END start-ver=1.4 cd-journal=joma no-vol=17 cd-vols= no-issue=2 article-no= start-page=63 end-page=76 dt-received= dt-revised= dt-accepted= dt-pub-year=1963 dt-pub=196304 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Studies on the compound lipids from X-ray irradiated animal,2. en-subtitle= kn-subtitle= en-abstract= kn-abstract=For the purpose to clarify the causes of X-ray disturbances a series of experiments have been conducted on biological and biochemical properties of compound lipids extracted from normal and X-ray irradiated rabbit organs with a special reference to the P??-labeled compound lipids uptake, inhibitory action to L cell proliferation and uncoupling of oxidative phosphorylation, and the following results have been obtained. The compound lipids (lysophosphatide rich fraction) isolated from the X-ray irradiated rabbit organ have been found to possess a strong hemolytic action and also an action to inhibit the cell proliferation as well as to accelerate the respiration of the mitochondria in the rabbit liver and spleen. It has also been proven that they act as to induce a marked swelling of mitochondria, to impede the formation of high energy phosphate as well as to act as an uncoupler of oxidative phosphorylation in vivo. In the test to see the uptake of P??-labeled compound lipids by various organs, a marked uptake has been observed in spleen, bone marrow, and liver of both irradiated and non-irradiated groups. Further, the uptake of P??-labeled compound lipids in the rabbits given intravenous injections of compound lipid fraction for 30 consecutive days previously has been found to be greatest in pancreas followed by bone marrow, spleen, liver in the order mentioned in male group, whereas it is greatest in spleen, followed by liver and bone marrow in the female group. With these results the discussion was conducted concerning the relation between the lipid metabolism and X-ray disturbances.
en-copyright= kn-copyright= en-aut-name=OharaSachiko en-aut-sei=Ohara en-aut-mei=Sachiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=Okayama University END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=2 article-no= start-page=118 end-page=138 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=196006 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Infeluences of adrenalin, cortisone and ACTH on eosinophils in bone marrow tissue culture (With some sug?gestions for examining the anterior pituitary function) en-subtitle= kn-subtitle= en-abstract= kn-abstract=1. Adrenalin, when acting directly on eosinophils, brings about a diminution in the wandering velocity of eosinophils but it has no influence on the number of the cells. Judging from the movement patterns of eosinophils this drug acts as to impede the motive function. 2. Acting directly on eosinophils, cortisone markedly decreases the wandering velocity of these cells and also brings about the diminution in the number of the cells. Likewise from the movement patterns of eosinophils, this drug markedly impedes the motive function of the cells. 3. ACTH (adrenocorticotropic hormone), when acting directly on eosinophils, enhances the wandering velocity of eosinophils but it in no way affects the number of eosinophils. Judging from the eosinophil movement patterns, this drug markedly promotes the motive function. 4. Although adrenalin brings about a decrease in the number of peripheral eosinophils in hypophysectomized dogs, the rate of the decrease is less than that observable in the case of normal dogs. 5. Cortisone brings about no significant change in the number of peripheral eosinophils in hypophysectomized dogs, but is induces a decrease in peripheral eosinophils of normal dogs. 6. ACTH acts as to decrease the number of peripheral eosinophils to an equal. degree in both hypophysectomized and normal dogs. 7. When cortisone is administered simultaneously with Adrex, a marked decrease in peripheral eosinophils is brought about in hypophysectomized dogs. 8. By means of the bone-marrow tissue culture of hypophysectomized dogs it has been confirmed that the blood plasma of hypophysectomized dogs lacks an essential factor for cortisone to induce eosinopenia in perpheral blood. 9. The decrease in eosinophils of peripheral blood induced by cortisone has been proved to be dependent upon the presence or absence of the pituitary body. 10. Taking the decrease in peripheral eosinophils by cortisone administration as the criterion, the author has carried out clinical observations with this method and obtained anticipated results.
en-copyright= kn-copyright= en-aut-name=YamamotoSinro en-aut-sei=Yamamoto en-aut-mei=Sinro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=Okayama University END start-ver=1.4 cd-journal=joma no-vol=63 cd-vols= no-issue=3 article-no= start-page=137 end-page=144 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=200906 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Infusion of Hypertonic Saline into the Lung Parenchyma during Radiofrequency Ablation of the Lungs with Multitined Expandable Electrodes:Results Using a Porcine Model en-subtitle= kn-subtitle= en-abstract= kn-abstract=The present study was performed to clarify the effect of hypertonic saline infusion into the lung parenchyma on radiofrequency ablation (RFA) of the lungs. A total of 20 ablation zones were created in 3 pigs. The ablation zones were divided into 3 groups. Group 1 (n6) consisted of ablation zones created by applying smaller radiofrequency (RF) power without saline infusion;group 2 (n5) zones were created by applying greater RF power without saline infusion;and group 3 (n9) zones were created by applying greater RF power with saline infusion. The techniques of saline infusion included administration of hypertonic saline 1ml before RFA, followed by continuous administration at a rate of 1ml/min during the first 2min after the initiation of RFA. The ablation parameters and coagulation necrosis volumes were compared among the groups. Group 3 had a tendency toward smaller mean impedance than group 1 (p0.059) and group 2 (p0.053). Group 3 showed significantly longer RF application time than group 2 (p0.004) and significantly greater maximum RF power than group 1 (p0.001) and group 2 (p0.004). Group 3 showed significantly larger coagulation necrosis volume (mean, 1,421mm3) than group 2 (mean, 858mm3, p0.039) and had a tendency toward larger necrosis volume than group 1 (mean, 878mm3, p0.077). Although this small study had limited statistical power, hypertonic saline infusion during RFA appeared to enlarge coagulation necrosis of the lung parenchyma.
en-copyright= kn-copyright= en-aut-name=IishiTatsuhiko en-aut-sei=Iishi en-aut-mei=Tatsuhiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HirakiTakao en-aut-sei=Hiraki en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MimuraHidefumi en-aut-sei=Mimura en-aut-mei=Hidefumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=GobaraHideo en-aut-sei=Gobara en-aut-mei=Hideo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KuroseTaichi en-aut-sei=Kurose en-aut-mei=Taichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=FujiwaraHiroyasu en-aut-sei=Fujiwara en-aut-mei=Hiroyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SakuraiJun en-aut-sei=Sakurai en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=YanaiHiroyuki en-aut-sei=Yanai en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=YoshinoTadashi en-aut-sei=Yoshino en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=KanazawaSusumu en-aut-sei=Kanazawa en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=2 en-affil= kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=3 en-affil= kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=4 en-affil= kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=5 en-affil= kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=6 en-affil= kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=7 en-affil= kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=8 en-affil= kn-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=9 en-affil= kn-affil=Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=10 en-affil= kn-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences en-keyword=radiofrequency ablation kn-keyword=radiofrequency ablation en-keyword=lung kn-keyword=lung en-keyword=experimental study kn-keyword=experimental study END start-ver=1.4 cd-journal=joma no-vol=26 cd-vols= no-issue=2 article-no= start-page=968 end-page=970 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19903 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Finite element analysis of induced currents in axisymmetric multi-conductors connected in parallel to voltage sources en-subtitle= kn-subtitle= en-abstract= kn-abstract=A method for analyzing induced currents, including both eddy currents and circulating currents, in axisymmetric multiconductors connected in parallel to voltage sources has been developed using the finite-elements method. The method has the advantage that the nonlinear analysis of induced currents in conductors connected to voltage sources with distorted waveforms (for example, an inverted-fed transformer) is possible. Because the method can take into account the voltage sources, the external impedances, and the nonlinearity of the core it becomes possible to analyze flux and current distributions under actual operating conditions and to design windings which produce the minimum power loss. The effectiveness of the method is illustrated by applying it to a transformer model
en-copyright= kn-copyright= en-aut-name=NakataTakayoshi en-aut-sei=Nakata en-aut-mei=Takayoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakahashiN. en-aut-sei=Takahashi en-aut-mei=N. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FujiwaraK. en-aut-sei=Fujiwara en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NiinobeH. en-aut-sei=Niinobe en-aut-mei=H. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MisawaK. en-aut-sei=Misawa en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Nissin Electric Company Limited en-keyword=conductors (electric) kn-keyword=conductors (electric) en-keyword=eddy currents kn-keyword=eddy currents en-keyword=electromagnetic induction kn-keyword=electromagnetic induction en-keyword=finite element analysis kn-keyword=finite element analysis en-keyword=machine windings kn-keyword=machine windings en-keyword=magnetic flux kn-keyword=magnetic flux en-keyword=transformer windings kn-keyword=transformer windings END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=112 end-page=117 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=199611 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Application of rubber artificial muscle manipulator as a rehabilitation robot en-subtitle= kn-subtitle= en-abstract= kn-abstract=The application of robot to rehabilitation has become a matter of great concern. This study deals with an exercise for restoration of function being one of important rehabilitation tasks. An exercise of single joint has already been achieved with some automatically controlled machines. Now, the multijoint exercise becomes desirable, which requires the exercise robot with multi ple degrees of freedom to generate more realistic motion pattern. This kind of robot has to be absolutely safe for humans. A pneumatic calculator may be so effective for such a robot because of the flexibility from air compressibility that a rubber artificial muscle manipulator pneumatically driven is applied to construct the exercise robot with two degrees of freedom. Also an impedance control strategy is employed to realize various exercise motion modes. Further, an identification method of the recovery condition is proposed to execute the effective rehabilitation. Some experiments show the availability of proposed rehabilitation robot system
en-copyright= kn-copyright= en-aut-name=NoritsuguToshiro en-aut-sei=Noritsugu en-aut-mei=Toshiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TanakaToshihiro en-aut-sei=Tanaka en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YamanakaTakashi en-aut-sei=Yamanaka en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Bridgestone Corporation en-keyword=actuators kn-keyword=actuators en-keyword=manipulators kn-keyword=manipulators en-keyword=patient treatment kn-keyword=patient treatment en-keyword=pneumatic control equipment kn-keyword=pneumatic control equipment END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=259 end-page=267 dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=199712 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Application of rubber artificial muscle manipulator as a rehabilitation robot en-subtitle= kn-subtitle= en-abstract= kn-abstract=The application of a robot to rehabilitation has become a matter of great concern. This paper deals with functional recovery therapy, one important aspect of physical rehabilitation. Single-joint therapy machines have already been achieved. However, for more efficient therapy, multjoint robots are necessary to achieve more realistic motion patterns. This kind of robot must have a high level of safety for humans. A pneumatic actuator may be available for such a robot, because of the compliance of compressed air. A pneumatic rubber artificial muscle manipulator has been applied to construct a therapy robot with two degrees of freedom (DOF). Also, an impedance control strategy is employed to realize various motion modes for the physical therapy modes. Further, for efficient rehabilitation, it is desirable to comprehend the physical condition of the patient. Thus, the mechanical impedance of the human arm is used as an objective evaluation of recovery, and an estimation method is proposed. Experiments show the suitability of the proposed rehabilitation robot system
en-copyright= kn-copyright= en-aut-name=NoritsuguToshiro en-aut-sei=Noritsugu en-aut-mei=Toshiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TanakaToshihiro en-aut-sei=Tanaka en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University en-keyword=actuators kn-keyword=actuators en-keyword=biomedical equipment kn-keyword=biomedical equipment en-keyword=manipulators kn-keyword=manipulators en-keyword=patient treatment kn-keyword=patient treatment en-keyword=pneumatic control kn-keyword=pneumatic control en-keyword=equipment kn-keyword=equipment en-keyword=safety kn-keyword=safety END start-ver=1.4 cd-journal=joma no-vol=33 cd-vols= no-issue=2 article-no= start-page=45 end-page=50 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990427 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Measurement System of Biomechanical Properties for Portable Use en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is difficult to evaluate a biomechanical properties quantitatively. The authors developed the measurement system of biomechanical properties formerly but it is on a large scale because of the use of personal computer. In this study, the portable measurement system of biomechanical impedance/mobility is developed. To establish a rapid measurement, a random vibration is adopted in input signal. The system consists of the measuring probe, amplifier, and a note-typed personal computer. The measurement probe is developed newly, and has an overall length of 9 p (without a handle) and a total weight of about 500 g. The measurement program is also developed and is available to any computer which is worked under MS DOS compatible in Windows 95/98 operating system. The biomechanical spectra of thigh, temple and forehead are obtained and they show three typical spectrum patterns. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=YamadaNobuya kn-aut-sei=Yamada kn-aut-mei=Nobuya aut-affil-num=1 ORCID= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=岡久雄 kn-aut-sei=岡 kn-aut-mei=久雄 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical and Electronic Engineering affil-num=2 en-affil= kn-affil=Department of Electrical and Electronic Engineering END start-ver=1.4 cd-journal=joma no-vol=2009 cd-vols= no-issue=1 article-no= start-page=88 end-page=93 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20091111 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Analysis of Human Hand Impedance Properties Depending on Driving Conditions en-subtitle= kn-subtitle= en-abstract= kn-abstract=This paper examines the influence of driving conditions on human hand impedance properties by using an originally developed driving simulator. A set of driving tests combining driving speed and the existence of a road centerline was carried out with five subjects. The results statistically demonstrate that humans steer a vehicle with increasing hand stiffness by activating arm muscles, i.e., under some tension, on the straight load especially at a lower speed with a centerline. In addition, it was confirmed that there was a clear correlation between steering behaviors and human hand stiffness according to the driving conditions. Human impedance measurement in driving would be useful to ascertain not only steering behaviors but also driver's physical and mental conditions for driving conditions, which may be required to develop an intelligent driving support system. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=KashibaYusuke kn-aut-sei=Kashiba kn-aut-mei=Yusuke aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=TanakaYoshiyuki kn-aut-sei=Tanaka kn-aut-mei=Yoshiyuki aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=TsujiToshio kn-aut-sei=Tsuji kn-aut-mei=Toshio aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=YamadaNaoki kn-aut-sei=Yamada kn-aut-mei=Naoki aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=SuetomiTakamasa kn-aut-sei=Suetomi kn-aut-mei=Takamasa aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Hiroshima University affil-num=2 en-affil= kn-affil=Hiroshima University affil-num=3 en-affil= kn-affil=Hiroshima University affil-num=4 en-affil= kn-affil=Mazda Motor Corporation affil-num=5 en-affil= kn-affil=Mazda Motor Corporation END start-ver=1.4 cd-journal=joma no-vol=2009 cd-vols= no-issue=1 article-no= start-page=82 end-page=87 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20091111 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Development of an evaluation tool for a driving seat reducing neck injury based on mechanical impedance en-subtitle= kn-subtitle= en-abstract= kn-abstract=The importance of developing a driving seat effective for reducing neck injuries caused by rear-end collisions has been increased to produce a safer automobile against vehicle accidents in recent years. The present paper develops a computer simulator based on a mechanical impedance model for analyzing and designing an effective driving seat reducing neck injuries. The simulator can reproduce dynamic behaviors of a dummy doll measured in an actual test of rear-end collision. Effectiveness of an active headrest, which is developed for reducing neck injuries, is quantitatively evaluated through a set of computer simulations. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=FukushimaShunsuke kn-aut-sei=Fukushima kn-aut-mei=Shunsuke aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=NomotoYuhei kn-aut-sei=Nomoto kn-aut-mei=Yuhei aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=TanakaYoshiyuki kn-aut-sei=Tanaka kn-aut-mei=Yoshiyuki aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=TsujiToshio kn-aut-sei=Tsuji kn-aut-mei=Toshio aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=TakeshimaToru kn-aut-sei=Takeshima kn-aut-mei=Toru aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=YamashitaMasaya kn-aut-sei=Yamashita kn-aut-mei=Masaya aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Hiroshima University affil-num=2 en-affil= kn-affil=Hiroshima University affil-num=3 en-affil= kn-affil=Hiroshima University affil-num=4 en-affil= kn-affil=Hiroshima University affil-num=5 en-affil= kn-affil=DELTA KOGYO CO.,LTD. affil-num=6 en-affil= kn-affil=DELTA KOGYO CO.,LTD. END start-ver=1.4 cd-journal=joma no-vol=32 cd-vols= no-issue=1-2 article-no= start-page=15 end-page=22 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980420 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Internal Structure and Viscoelasticity Estimation by a Mechanical Impedance - In case of a vibrating disk - en-subtitle= kn-subtitle= en-abstract= kn-abstract=In a stiffness estimation of living body, an internal structure under the skin influences the measured results. Because a different stiffness of body caused by bones and muscles is obtained. In this paper, by using a measurement system of mechanical impedance, the relations between a viscoelasticity and a distance from the surface of silicone-gel model is calculated. This relation is applied to silicone-gel tumor model and a shape and a viscoelasticity of semi-sphere silicone-gel tumous are estimated. The obtained results are expressed as a reconstructed 3-D image of shape / viscoelasticity. The revised curve-fitting of mechanical impedance and the cancellation of peripheral vibration influence are proposed in order to increase an estimation acccuracy. en-copyright= kn-copyright= en-aut-name=MoriMasahiro en-aut-sei=Mori en-aut-mei=Masahiro kn-aut-name=森政弘 kn-aut-sei=森 kn-aut-mei=政弘 aut-affil-num=1 ORCID= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=岡久雄 kn-aut-sei=岡 kn-aut-mei=久雄 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical and Electronic Engineering affil-num=2 en-affil= kn-affil=Department of Electrical and Electronic Engineering END start-ver=1.4 cd-journal=joma no-vol=31 cd-vols= no-issue=2 article-no= start-page=21 end-page=27 dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=19970328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Estimation of Internal Viscoelasticity by Mechanical Impedance en-subtitle= kn-subtitle= en-abstract= kn-abstract=In evaluating the stiffness of skin surface, internal structures such as bone and muscle often affect the measurements. In the present paper, acoustic random vibration is used to estimated the viscoelasticity of a silicone-gel model. This viscoelasticity, which includes two different stiffness strata, is first estimated using a mechanical impedance spectrum, which describes the relation between the depth and viscoelasticity of internal objects. This method is applied to the depth of a silicone-gel tumor model measured by ultrasound imaging and the viscoelasticity of internal gel can be accurately estimated. en-copyright= kn-copyright= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=岡久雄 kn-aut-sei=岡 kn-aut-mei=久雄 aut-affil-num=1 ORCID= en-aut-name=NakamuraTakahiko en-aut-sei=Nakamura en-aut-mei=Takahiko kn-aut-name=中村貴彦 kn-aut-sei=中村 kn-aut-mei=貴彦 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical and Electronic Engineering affil-num=2 en-affil= kn-affil=Department of Electrical and Electronic Engineering END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=12 article-no= start-page=4431 end-page=4441 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19581231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Action of KCN and NaN(3) on the Bacterial Metabolism Part 2. The Enzymatic Behaviors of Bacteria in Culture in the Medium loaded with KCN or NaN(3) kn-title=細菌の代謝に於けるKCN, NaN(3)の作用 第2篇 KCN, NaN(3)添加培地培養菌の酵素的性状 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Using the standard strains such as Sh. flexneri 2 a, St. aureus and St. albus that are stocked in our laboratory, the author studied the glucolysis of these bacteria in the course of culture in the medium containing KCN or NaN(3) and also compared the enzymatic behaviors of each kind of bacteria in resting state while being cultured in the medium loaded with KCN or NaN(3). The results are as follows: 1. Both Sh. flexneri 2 a and St. aureus grow well in the medium loaded with 10?? M KCN or NaN(3), and in the medium loaded with 10?? M KCN th growth of St. albus is somewhat impeded but this strain grows well in the medium loaded with 10?? M NaN(3). 2. When KCN or NaN(3) is added to the medium in the course of bacteria culture, the glycolysis tends to be anaerobic; and morever, by the addition of KCN the accumulation of lactic acid increases, while by the addition of NaN(3) the accumulation of acetic acid. 3. On comparing the catalase and peroxidase activities of bacteria cultured in the medium loaded with KCN or NaN(3), both Sh. flexneri 2 a and St. albus lose their catalase and peroxidase activities in the medium loaded with 10?? M KCN or NaN(3); while St. aureus likewise does not show these enzymatic activities in the medium loaded with 10?? M NaN(3), but this strain retains these enzymatic activities to a marked degree in the medium loaded with 10?? M KCN. 4. In these bacteria being cultured in the medium containing KCN the enzymatic activity of lactic acid production from glucose is great, while in these bacteria cultured in the medium containing NaN(3) the acetic acid production from glucose is great. en-copyright= kn-copyright= en-aut-name=TanakaTakao en-aut-sei=Tanaka en-aut-mei=Takao kn-aut-name=田中孝男 kn-aut-sei=田中 kn-aut-mei=孝男 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=12 article-no= start-page=4339 end-page=4350 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19581231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Morphological and Histological Studies on Rosenmuller's Fossa Part 3. The Histological Study on Rosenmuller's Fossa kn-title=ローゼンミュラー氏窩の形態学竝びに組織学的研究 第3編 ローゼンミュラー氏窩の組織学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Comparative histological observations were carried out on lymphoid tissue of Rosenmuller's fossa in the order of ages, and also the relationship between the thickening of the capsule of lymphoid tissue in R. Fossa and the hypertrophy of lymphoid tissues was studied. The maximum development of lymphoid tissues is reached at the age of four, and the size and number of lymph follicles are also greatest at four, and both the size and number decrease progressively in the order of 2 years and six months, 14 years old, 25 years, and one full year old. In older children and adults some show large retention cysts and multiple cysts; and certain ones clearly indicate that these malformations are caused by the dilatation of the excretory duct of lymphatic glands. Moreover, there are some revealing big adhesions bridging across the anterior and posterior walls of R. fossa. It is believed that the hypertrophy of lymphoid tissues in R. Fossa, big adhesions and formation of cysts as observed in adults impede the backward and upward movement of Torus tubaris and these constitute the cause of tubal stenosis. en-copyright= kn-copyright= en-aut-name=KanatakiKenjiro en-aut-sei=Kanataki en-aut-mei=Kenjiro kn-aut-name=金滝憲次郎 kn-aut-sei=金滝 kn-aut-mei=憲次郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部耳鼻咽喉科教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=7 article-no= start-page=2591 end-page=2598 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580731 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Anemia in Anchylosot. miasis by means of Bone Marrow Tissue Culture Part 3. Influences of an Addition of the Serum of Hook Worm Dogs on Bone Marrow Tissue Culture kn-title=骨髄組織培養による鉤虫症貧血の本態に関する研究 第3編 鉤虫犬血清添加が同種骨髄組織培養に及ぼす影響 附 全編の総括 en-subtitle= kn-subtitle= en-abstract= kn-abstract=By adding a drop of the serum of dogs with ancylostomiasis in the medium of bone marrow tissue culture of normal dogs, the author has examined its influences on the growth rate, white blood cell function (wandering velocity, phagocytosis of carbon particles and vital staining of neutral red) in hanging drop culture and increasing rate of the red blood cell count and hemoglobin content in fluid culture. 1) As for the growth rate, it was slightly increased in the later atage of tissue culture. 2) Function of the neutrophils was not impedented on wandering velocity, phagocytosis of carbon particles and vital staining of neutral red, but rather slightly accerelated in the early stage of tissue culture. 3) According to the above mentioned results, the author has presumed that some stimulative substances for the bone marrow activity and neutrophils function are contained in the serum of hook wormdog. 4) Wandering velocity of the eosinophils was slightly increased, so that the author has resumed that it had occured from the stimulation of hook worm toxin possessing positive taxis for the eosinophils. 5) Increasing rate of the red blood cell count was not suffered from by adding the serum of hook worm dog on fluid culture, but that of hemoglobin content was slightly declined, which did not come from the restrain of hook worm toxin for the formation of hemoglobin, but from iron deficiency in the serum. en-copyright= kn-copyright= en-aut-name=YumotoMasaru en-aut-sei=Yumoto en-aut-mei=Masaru kn-aut-name=柚本賢 kn-aut-sei=柚本 kn-aut-mei=賢 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=6 article-no= start-page=2181 end-page=2189 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Studies on Ligation of Inferior Vena Cava. U. Studies of Peripheral Circulation by Means of Radioisotope P(32) kn-title=下空静脈結紮術に関する実験的研究 第2編 放射性同位元素による下肢末梢循環について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Radioisotope P(32) was injected intramuscularly, subcutaneously, and intracutaneously on the lower leg of rabbit before and after ligation of inferior vena cava. Muscle, subcutaneous, and skin circulations were calculated by local clearance method (Kety) in each case. The following results were obtained. 1) Muscle circulation is markedly impeded immediately after ligation and is restored to normal two or three weeks later with gradual improvement. 2) Subcutaneous and skin circulation are not correlated to muscle circulation following ligation. 3) Skin circualtion is accelerated after ligation. 4) Lumbar sympathetic blockade and injection of Imidalin improved muscle circulation following ligation. 5) Influence of ligation of femoral vein on muscle circulation is less than that in the case of inferior vena cava. en-copyright= kn-copyright= en-aut-name=MotoyoshiMasaharu en-aut-sei=Motoyoshi en-aut-mei=Masaharu kn-aut-name=本吉正晴 kn-aut-sei=本吉 kn-aut-mei=正晴 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部砂田外科教室 END start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue=4-6 article-no= start-page=441 end-page=453 dt-received= dt-revised= dt-accepted= dt-pub-year=1961 dt-pub=19610630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Effects of Various Anti-Leukemic Agents by Means of Sternal Bone Marrow Tissue Culture of Various Leukemic Patients Part 2. On the Effects of Various Antibiotics and OX Substance by Clinical Tissue Culture of Bone Marrow kn-title=各種白血病患者胸骨骨髄培養に於ける各種抗白血病剤の影響に関する研究 第U編 臨床組織培養による抗生物質及びOX物質の影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=In order to elucidate the effects of various antibiotics (carzinophilin, actinomycin C, chromomycin, mitomycin) and OX substance on the function of leukemic cells, the author performed clinical tissue culture of bone marrow of various leukemic patients. First the author performed bone marrow tissue culture of normal persons with addition of various antibiotics and OX substance in graded concentrations and established the maximal concentration of the agents in the medium, which does not impede the bone marrow cell growth. The author observed the effect of direct addition of various antibiotics and OX substance at this maximal concentration on the relative growth of the tissue, the wandering velocity of the cells, and the cell density in the bone-marrow tissue culture of various leukemic patients; and obtained the following results: 1. In acute myelogenous leukemia chromomycin and actinomycin C acted somewhat inhibitorily on the cell growth of the bone marrow. 2. In chronic myelogenous leukemia the inhibitory effect was found, though only slightly, to be in the descending order of carzinophilin, mitomycin, chromomycin and OX substance. 3. In acute lymphocytic leukemia and in chronic lymphocytic leukemia, no agents acted inhibitorily on the cell growth of the bone marrow. 4. In monocytic leukemia mitomycin showed an inhibitory effect to a moderate degree. 5. Judging from the effects of these drugs on leukemic cells, it may be expected that the efficacy of these drugs in the treatment of various leukemias is as follows: In actue myelogenous leukemia chromomycin is mildly effective; in chronic myelogenous leukemia carzinophilin is also mildly effective; and in monocytic leukemia mitomycin mildly effective. en-copyright= kn-copyright= en-aut-name=NabeshimaSaburo en-aut-sei=Nabeshima en-aut-mei=Saburo kn-aut-name=鍋島三朗 kn-aut-sei=鍋島 kn-aut-mei=三朗 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue=4-6 article-no= start-page=427 end-page=440 dt-received= dt-revised= dt-accepted= dt-pub-year=1961 dt-pub=19610630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Effects of Various Anti-Leukemic Agents by Means of Sternal Bone-Marrow Tissue Culture of Various Leukemias Part 1. On the Effects of Urethane and Various Alkylating Agents by Clinical Tissue Culture of Bone Marrow kn-title=各種白血病患者胸骨骨髄培養に於ける各種抗白血病剤の影響に関する研究 第T編 臨床組織培養によるウレタン及び細胞毒性物質の影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=With the purpose clarify the effects of urethane and various alkylating agents(nitromin, myleran, colcemid, tespamin) of the function of leukemic cells, the author performed clinical tissue culture of bone marrow of various leukemic patients First the author performed bone-marrow tissue culture of normal persons with addition of urethane and various alkylating agents in graded concentrations and established the maximal concentration of the agents in the medium, which does not impede bone-marrow cell growth. At this maximal concentration the observation was carried on to see the effect of direct addition of urethane and various alkylating agents on the relative growth of the tissue, the wandering velocity of the cells, and the cell density by performing bone-marrow tissue culture of various Ieukemic patients; and obtained the following results: 1. In acute myelogenous leukemia the inhibitory effect on the bone-marrow cell growth was found to be in the descending order of nitromin, myleran, urethane, colcemid, and tespamin, and it was greatest with nitromin. 2. In chronic myelogenous leukemia the inhibitory effect was found to be in the descending order of nitromin, myleran, urethane, colcemid and tepsamin, and it was marked with nitromin and myleran. 3. In acute lymphocytic leukemia nitromin acted inhibitorily slightly, but other anti-leukemic agents had hardly any inhibitory action. 4. In chronic lymphocytic leukemia the inhibitory effect was found to be in the descending order of tepsamin, urethane, colcemid, nitromin and myleran; among them tespamin and urethane were more effective. 5. In monocytic leukemia moderately inhibitory effect could be recognized in the descending order of nitromin, colcemid, urethane, tespamin and myleran; of them nitromin proved to be more effective. 6. Judging from the effects of these agents on leukemic cells in the treatment of leukemias, one might anticipate the efficacy of these drugs as follows: i. e. in acute myelogenous leukemia nitromin is most effective; in chronic myelogenous leukemia nitromin and myleran are most effective; in chronic lymphocytic leukemia tespamin and urethane are most effective; and in monocytic leukemia nitromin is most effective. en-copyright= kn-copyright= en-aut-name=NabeshimaSaburo en-aut-sei=Nabeshima en-aut-mei=Saburo kn-aut-name=鍋島三朗 kn-aut-sei=鍋島 kn-aut-mei=三朗 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue=4-6 article-no= start-page=399 end-page=407 dt-received= dt-revised= dt-accepted= dt-pub-year=1961 dt-pub=19610630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Anti-leukemic Chemical Agents -By the Bone-Marrow Tissue Culture- T. The Effects of Anti-leukemic Chemical Agents on the Bone-Marrow Tissse Culture of Normal Rabbit and Normal Person kn-title=抗白血病剤に関する研究―骨髄体外組織培養による― 第T編 正常家兎及び健康人胸骨骨髄被覆培養に及ぼす抗白血病剤の影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In order to clarify the effects of anti-leukemic clemical agents-antimetabolites (Azan, 6MP, T-431L), hormones (ACTH, Cortisone, Prednisolone)-on the hematopoietic function of bone marrow, especially on the leucocyte series, the author observed the effects of direct addition of these chemical agents on the tissue growth area, the cell density, and the wandering velocity of pseudoeosinophils of the bone marrow by performing the tissue culture of the normal rabbit bone marrow. Likewise, the bone-narrow tissue culture of normal persons has been performed with the addition of several anti-leukemic chemical agents at various concentrations, and established the maximal concentration of the agents in the medium as to not impede the bone-marrow growth; and obtained the following results. 1. Any one of anti-leukemic agents acts inhibitorily on the cell growth and the wandering velocity of the cells of the bone marrow at a higher concentration than at a certain fixed concentration. Of the anitmetabolites used in the present experiments, the inhibitory effect is strong in the descending order of T-431L, Azan and 6MP; and of the hormones it is in the order of Prednisolone, Cortisone and ACTH. 2. The maximal concentration of the media with addition of several anti-leukemic agents, which do not impede the growth of the bone marrow of normal persons is 0.035 mg/ml for Azan; 0.05 mg./ml. for 6MP; 0.01 mg/ml. for T-431L; 0.01 mg/ml. for ACTH; 0.01 mg/ml. for Cortisone ; and 0.01 mg/ml. for Prednisolone. en-copyright= kn-copyright= en-aut-name=SatoShiro en-aut-sei=Sato en-aut-mei=Shiro kn-aut-name=佐藤四郎 kn-aut-sei=佐藤 kn-aut-mei=四郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=8-10 article-no= start-page=1775 end-page=1782 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19601030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the DNA and Protein Synthesis in the Cell II. Effect of OX on the DNA and Protein Contents in the Cell kn-title=細胞内DNA及び蛋白合成に関する研究 II. 細胞内DNA量，蛋白量に与えるOXの作用 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Using sea-urchin eggs, Euplotes woodruffi, HeLa cells, and Ehrlich ascites tumor cells, the author studied the action of OX substance on the DNA and protein synthesis of these cells, and obtained the following results. 1. OX substance has been found to act as to impede the incorporation of (32)P to DNA in Ehrlich ascites tumor cells. 2. OX substance leads the nuclei of Euplotes, HeLa and Ehrlich ascites tumor cells into a picnotic state. 3. OX substance is found to possess an action to diminish the DNA contents in the nuclei of HeLa and Ehrlich ascites tumor cells while it tends to increase transiently the DNA content in the nucleus of sea-urchin egg but later decreases it. 4. It has been found that OX substance brings about the disturbance on the mitotic apparatus or the functional disturbance in Ehrlich ascites tumor cells and sea-urchin eggs. 5. In addition, this substance acts as to inhibit the protein synthesis of Ehrlich ascites tumor cells. 6. From these findings, it seems that OX acts temporarily on the mitotic apparatus, thus interfering with the cell division as well as giving rise to the degeneration of the cells. accompanied by the secondary inhibition of the synthesis of DNA and RNA in the cells. en-copyright= kn-copyright= en-aut-name=UenoHisako en-aut-sei=Ueno en-aut-mei=Hisako kn-aut-name=上乃寿子 kn-aut-sei=上乃 kn-aut-mei=寿子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=4 article-no= start-page=1005 end-page=1009 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical Effect of Yakult (Cow's Milk Fermented by Some Sort of “Family Lactbacillaceae” Commonly Sold as a Soft Drink) Part II. Fluctuation of Vitamin B(1) in the Urine After Drinking Yakult kn-title=乳酸菌ヤクルトの臨床効果に就て（第二報）（抗結核化学療養患者に於ける変化） 其の二 市販ヤクルト飲用による尿中ビタミンB1の消長 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In order to determine the fluctuation of vitamin B(1) in the urine after drinking "Yakult", cow's milk fermented by some sort of "Family Lactbacillaceae", the authors made normal adults and patients with lung tuberculosis drink one bottle (60 cc) a day of Yakult successively, and estimated their content of vitamin B(1) in their urine polarographically and with paper chromatography. Results are as follows. 1. In the case of one bottle (60 cc) of Yakult successively, there occurs a little increment of vitamin B(1) content in their urine of normal adults comparing with tuberculous patients receiving chemotherapy. 2. In the case of taking one bottle of Yakult, no marked effect can be recognized in their urine of tuberculous patients receiving chemotherapy. However, when three bottles (180 cc) of Yakult are given every day, marked increase of vitamin B(1) can be observed even in their urine of the patients, and also impeding factor in polarographical estimation disappears, proving that Yakult is considerably effective in improving vitamin B(1) metabolism. en-copyright= kn-copyright= en-aut-name=NanbaHisao en-aut-sei=Nanba en-aut-mei=Hisao kn-aut-name=難波寿夫 kn-aut-sei=難波 kn-aut-mei=寿夫 aut-affil-num=1 ORCID= en-aut-name=OonisiHiroyuki en-aut-sei=Oonisi en-aut-mei=Hiroyuki kn-aut-name=大西弘之 kn-aut-sei=大西 kn-aut-mei=弘之 aut-affil-num=2 ORCID= en-aut-name=AritiSigeru en-aut-sei=Ariti en-aut-mei=Sigeru kn-aut-name=有地茲 kn-aut-sei=有地 kn-aut-mei=茲 aut-affil-num=3 ORCID= en-aut-name=MikiHukuziro en-aut-sei=Miki en-aut-mei=Hukuziro kn-aut-name=三木福治郎 kn-aut-sei=三木 kn-aut-mei=福治郎 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山県乳酸菌ヤクルト臨床研究所 affil-num=2 en-affil= kn-affil=岡山県乳酸菌ヤクルト臨床研究所 affil-num=3 en-affil= kn-affil=岡山県乳酸菌ヤクルト臨床研究所 affil-num=4 en-affil= kn-affil=岡山県乳酸菌ヤクルト臨床研究所 END start-ver=1.4 cd-journal=joma no-vol=88 cd-vols= no-issue=5-6 article-no= start-page=363 end-page=371 dt-received= dt-revised= dt-accepted= dt-pub-year=1976 dt-pub=19760630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on vectorcardiography Part T. Basic studies on vectorcardiography by Kimura system with special reference to Frank system kn-title=ベクトル心電図に関する研究 第T編 木村法ベクトル心電図の基礎的検討(とくにFrank法との対比) en-subtitle= kn-subtitle= en-abstract= kn-abstract=Using a human torso model which had been made up with reference to normal stature of Japanese adult male and using four types of elliptical cylinder model which have different longitudinal diameter, Kimura system and Frank system were studied from the standpoint of transfer impedeance, and following results were obtained. 1) In Kimura system, elevation of transfer impedance of X and Z leads deviated to upward about 15 degrees in comparison with the latter. Nevertheless, the former's orthogonality was maintained relatively well, and have been scarcely affected by the type of elliptical cylinder. 2) In Frank system, according to narrowing of longitudinal diameter of thorax, orthogonality of X and Z leads became worse and included angles of their transfer impedance became narrow. 3) In Kimura system, the ratio of transfer impedance of X to Y leads was about 1:3 in each model, therefore, frontal plane vectorcardiogram of Kimura system could be useful for diagnosis of cases whose heart-electromotive forces change vertically. 4) Much axis deviation could not be caused by the changes of position of artificial current dipole and longitudinal diameter of the thorax. en-copyright= kn-copyright= en-aut-name=NakagawaMasahiro en-aut-sei=Nakagawa en-aut-mei=Masahiro kn-aut-name=中川雅博 kn-aut-sei=中川 kn-aut-mei=雅博 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第I内科学教室 END start-ver=1.4 cd-journal=joma no-vol=87 cd-vols= no-issue=9-10 article-no= start-page=915 end-page=922 dt-received= dt-revised= dt-accepted= dt-pub-year=1975 dt-pub=19751030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Study on Lead Systems of Vectorcardiogram with Canine Homogenious Torso Model kn-title=犬のベクトル心電図誘導法の基礎的検討（伝達インピーダンスの観点から） en-subtitle= kn-subtitle= en-abstract= kn-abstract=The transfer impedance determined on Frank's lead system and McFee, Parungao's lead system using canine torso model was studied and following results were obtained. A simplyfied canine torso model was made, which was a cylinderic type imitated faithfully the transverse section in the fifth intercostal space of the canine. The canine which was used as a model has a body weight of 16.2kg. Its torso dimensions were left to right of 14.0cm, front to back of 19.0cm and height of 55.0cm. Its form was an oval on the whole shape with more gently curved surface on the front. Heart center on the dog determined by the X-ray located on the position which was 0.75cm to the left, 2.9cm to the front from the body center in the fifth intercostal soace. The definite dipole was placed on the heart center of the torso filled with 0.1% NaCl solution. Electrode position on the torso surface is defined by two quantities; levels (number 1 throngh 10) and angles in the transverse plane. The levels were separated each other at a distance of 3cm. Thus determined level 6 correspond to heart center level of the canine. The angles were taken each 5 or 10 around the cylinder whose plane passed precisely through the center of the body. Thus, potentials were determined and image surface was drawned on the loops. Image loops were oval and located on left anteriorly and slightly inferiorly from the heart center. As a result, canine image loop was found to be clearly different from the shape of the human's one which has a shape of a pear projecting slightly to the back. Then, normality and orthogonality were examined on the torso with the Frank's orthogonal lead system for human and with the McFee, Parungao's axial lead system for dog resulting the latter to be better than the former. en-copyright= kn-copyright= en-aut-name=FujitaTakashi en-aut-sei=Fujita en-aut-mei=Takashi kn-aut-name=藤田興 kn-aut-sei=藤田 kn-aut-mei=興 aut-affil-num=1 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斉藤大治 kn-aut-sei=斉藤 kn-aut-mei=大治 aut-affil-num=2 ORCID= en-aut-name=InoueKatsutoshi en-aut-sei=Inoue en-aut-mei=Katsutoshi kn-aut-name=井上勝稔 kn-aut-sei=井上 kn-aut-mei=勝稔 aut-affil-num=3 ORCID= en-aut-name=NakagawaMasahiro en-aut-sei=Nakagawa en-aut-mei=Masahiro kn-aut-name=中川雅博 kn-aut-sei=中川 kn-aut-mei=雅博 aut-affil-num=4 ORCID= en-aut-name=HiranoKazuhiro en-aut-sei=Hirano en-aut-mei=Kazuhiro kn-aut-name=平野和博 kn-aut-sei=平野 kn-aut-mei=和博 aut-affil-num=5 ORCID= en-aut-name=UedaMinoru en-aut-sei=Ueda en-aut-mei=Minoru kn-aut-name=上田稔 kn-aut-sei=上田 kn-aut-mei=稔 aut-affil-num=6 ORCID= en-aut-name=HisamatsuMitsuo en-aut-sei=Hisamatsu en-aut-mei=Mitsuo kn-aut-name=久松三生 kn-aut-sei=久松 kn-aut-mei=三生 aut-affil-num=7 ORCID= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院中央検査部 END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=1-2 article-no= start-page=101 end-page=113 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19790228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of colcemid and lidocaine on the avoidance training in mice kn-title=マウスの回避学習に及ぼすcolcemid及びlidocaineの影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Mice of the ddN strain with high training scores were selected for the study of genetic improvement through avoidance training. Mice used were from 7th to 9th generations. Colcemid and lidocaine, which are known to temporarily disrupt microtubules and impede axonal flow. In the present study the effect of these two drugs on learning behavior in mice were studied. Animals were injected with colcemid and lidocaine either intraperitoneally (50 μg in 0.5 ml) or intracerebrally (10 μg in 10 μl) on both sides of the frontal lobe to a depth of 3 mm. Injections were performed either before or after training sessions. Autoradiographic analysis confirmed that (3)H-colcemid injected intraperitoneally had been incorporated into the peripheral regions of the cerebral ventricles and had not extended into adjacent regions in less than one hour. Similally, (3)H-colcemid injected intracerebrally was shown to be incorporated into ventricle regions and to have extended into adjacent regions. Colcemid and lidocaine did not produce any remarkable change in open field activity of the mice. Intraperitoneal administration of colcemid and lidocaine did not affect either acquisition or retention of avoidance behavior. Intracerebral administraion of colcemid interfered only slightly with the acquisition and retention of avoidance behavior, but produced a profound loss of memory acquired previously. Intracerebral injection of lidocaine before or after training sessions did not affect either acquisition or retention of avoidance behaviour. en-copyright= kn-copyright= en-aut-name=ItamiYoshiaki en-aut-sei=Itami en-aut-mei=Yoshiaki kn-aut-name=伊丹義明 kn-aut-sei=伊丹 kn-aut-mei=義明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一生理学教室 END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue=11-12 article-no= start-page=1019 end-page=1032 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19811230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of neuropeptides on pancreatic glucagon secretion. Part II. Changes of pancreatic glucagon concentrations in the dog pancreatic vein after administration of 2-bromo-α-ergocryptine (CB154), gamma-aminobutyric acid (GABA), and gamma hydroxybutyric acid (GHB). kn-title=中枢神経系作動物質の膵グルカゴン分泌に対する効果 第二編 2-Bromo-α-Ergocryptine (CB 154), γ-Aminobutyric Acid (GABA), γ-Hydroxybutyric Acid (GHB) 負荷時のイヌ膵静脈血中の膵グルカゴンの変動 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Immunoreactive glucagon (using 30K antibodies) and insulin concentrations in the superior pancreaticoduodenal (pancreatic) vein of anesthetized mongrel dogs were measured after administration of 2-bromo-α-ergocryptine (CB154), γ-aminobutyric acid (GABA), and γ-hydroxybutyric acid (GHB) into the superior pancreaticoduodenal artery. A bolus administration of CB154 (200 μg/kg) induced a hyperglycemic response with biphagic increases in plasma glucagon and insulin levels. Blood pressure was lowered after a transient slight elevation. Impedance in pancreatic tissue was markedly increased after an initial rapid decrease. The lowered impedance reflects increased blood flow in the tissue. CB154 (50 μg/kg) administration brought about hyperglycemia and mild hyperglucagonemia. However, the plasma insulin level did not vary. After premedication with pimozide (1 mg/kg, intramuscularly), CB154 (200 μg/kg) administration caused a mild gradual increase of blood glucose, mild increase of plasma glucagon and significant decrease of plasma insulin concentrations. The premedication had no effect on blood pressure changes. Impedance in pancreatic tissue was slightly increased after a mild transient decrease. GABA (5 mg/kg) infusion for 30 min induced mild hyperglycemia, biphasic increase of pancreatic plasma glucagon and biphasic decrease of pancreatic plasma insulin concentrations. Blood pressure rose slightly, then gradually fell after a few minutes. Impedance in pancreatic tissue increased slowly. With a GABA (1 mg/kg) infusion for 5 min, the pancreatic plasma glucagon level gradually rose, and the plasma insulin level fell. During a GABA infusion at a dose of 0.1 mg/kg for 5 min, the plasma glucagon level increased slightly, but the plasma insulin level did not vary. A GHB (500 mg/kg for 2 min) infusion brought about a mild transient hyperglycemia. Although there was an initial decrease in the glucagon concentration, the amount of secreted glucagon seemed unchanged since the volume of blood flow in pancreatic tissue increased markedly during this period. The biphasic increase in glucagon concentration followed. Plasma insulin concentrations decreased significantly. GHB administration at a dose of 100 mg/kg for 2 min had similar effects on insulin and glucagon secretion, and did not cause any change in blood glucose level. The changes in plasma glucagon and insulin levels during 5 min infusion of GHB (100 mg/kg) were tested in more detail. The level of glucagon decreased slightly followed by a gradual increase after a few minutes. The plasma insulin level decreased significantly. GHB (10 mg/kg) infusion for 5 min resulted in no change of plasma glucagon concentration and a mild decrease in plasma insulin concentration. en-copyright= kn-copyright= en-aut-name=MachidaShuji en-aut-sei=Machida en-aut-mei=Shuji kn-aut-name=町田周治 kn-aut-sei=町田 kn-aut-mei=周治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第三内科学教室 en-keyword=グルカゴン kn-keyword=グルカゴン en-keyword=CB 154 kn-keyword=CB 154 en-keyword=Pimozide kn-keyword=Pimozide en-keyword=GABA kn-keyword=GABA en-keyword=GHB kn-keyword=GHB END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue=11-12 article-no= start-page=1009 end-page=1018 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19811230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of neuropeptides on pancreatic glucagon secretion. Part I. Changes of pancreatic glucagon concentrations in the dog pancreatic vein after administration of substance P. kn-title=中枢神経系作動物質の膵グルカゴン分泌に対する効果 第一編 Substance P負荷時のイヌ膵静脈血中の膵グルカゴンの変動 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It has been reported that substance P influences plasma glucagon concentrations; some investigators reported elevation of glucagon but the results are conflicting. This might be due to the differences in the species of experimental animal, dose of administered substance P, study system (in vivo or in vitro), and other experimental conditions. In this study, various doses of substance P were infused into the superior pancreaticoduodenal artery of anesthetized mongrel dogs for 30 min. Plasma glucagon and insulin concentrations in the superior pancreaticoduodenal (pancreatic) vein were measured by radioimmunoassay. For measuring plasma glucagon, 30K antibodies were used. Substance P (100 ng/kg body weight/min) infusion brought about mild hypoglycemia. A rapid and significant increase of plasma glucagon level was observed shortly after sub-stance P administration, then plasma glucagon concentrations decreased transiently during the next 10 to 20 min. Gradual increase to a high plateau level followed after discontinuation of the drug. A small transient decrease of plasma insulin level was seen at the beginning of the experiment. Blood pressure decreased during substance P infusion. Impedance in pancreatic tissue was markedly lowered. The lowered impedance reflects increased blood flow in the tissue. Administration of 25 or 50 ng/kg/min of substance P induced mild lowering of blood glucose and plasma insulin, but increase of plasma glucagon. The infusion of substance P at a dose of 5 ng/kg/min for 30 min did not cause any changes in blood glucose, plasma glucagon or insulin levels. But, after discontinuation of the drug, the plasma glucagon level gradually rose to a significantly high level. Blood pressure was not affected, but impedance in pancreatic tissue showed a gradual, marked decrease. During substance P infusion at a dose of 0.5ng/kg/min, blood-parameters did not vary. After ceasing the infusion, the plasma glucagon level gradually increased. In conclusion, substance P was thought to stimulate dose-related glucagon secretion not only by a neurogenic circulatory action, but also by a direct action on pancreatic alpha cells. The increase in glucagon concentration in the later part of the experiments might be caused by vaso-circulatory changes and other hormonal pharmacological actions of substance P. en-copyright= kn-copyright= en-aut-name=MachidaShuji en-aut-sei=Machida en-aut-mei=Shuji kn-aut-name=町田周治 kn-aut-sei=町田 kn-aut-mei=周治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第三内科学教室 en-keyword=substance P kn-keyword=substance P en-keyword=グルカゴン kn-keyword=グルカゴン en-keyword=インスリン kn-keyword=インスリン END start-ver=1.4 cd-journal=joma no-vol=93 cd-vols= no-issue=3-4 article-no= start-page=315 end-page=326 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19810430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A study on the position of chest electrodes for the Frank lead system Part I. A study using a human torso model kn-title=Frank誘導法の胸部電極の位置に関する研究 第1編 人体胴体模型による検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The effect of horizontal displacement of chest electrodes C, A and I for the Frank lead system on transfer impedance was studied in a human torso model. The results obtained were as follows: 1) With electrode C displaced 2 cm to the right of its original position, the magnitude of transfer impedance of lead Z increased by 6.3% and the azimuthal angle of transfer impedance of lead X deviated by 3.7%. A displacement of 2 cm to the left caused a decrease in the magnitude of the transfer impedance of lead Z of 5.6%. On the other hand, backward deviation changed the azimuthal angle of the transfer impedance of lead Z by 2.8°. 2) By moving electrodes A and I forward simultaneously by 2 cm the magnitude of the transfer impedance of lead X increased by approximately 5% while 2 cm backward-displacement of the electrodes decreased the magnitude of the transfer impedance of lead X by 5.7%. 3) With the center of the heart approaching the precordial wall, changes observed in 1) and 2) became conspicuous when the electrodes were on the left but obscure when the electrodes were located backwards or to the right. en-copyright= kn-copyright= en-aut-name=MiyasakaMinoru en-aut-sei=Miyasaka en-aut-mei=Minoru kn-aut-name=宮阪実 kn-aut-sei=宮阪 kn-aut-mei=実 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 en-keyword=Frank誘導法 kn-keyword=Frank誘導法 en-keyword=胸部電極 kn-keyword=胸部電極 en-keyword=人体胴体模型 kn-keyword=人体胴体模型 en-keyword=誘導ベクトル kn-keyword=誘導ベクトル en-keyword=X, Y, Z誘導 kn-keyword=X, Y, Z誘導 END start-ver=1.4 cd-journal=joma no-vol=98 cd-vols= no-issue=11-12 article-no= start-page=981 end-page=1005 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19861230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A study of body surface isopotential mapping in the normal aged Japanese kn-title=健常高齢者の体表面電位図の検討 ―QRS・T波について― en-subtitle= kn-subtitle= en-abstract=To examine the changes in the body surface isopotential maps (maps) with the increase of age, recorded maps at 87 lead points of 296 normal healthy adults, and I analyzed maps comparatively among six groups. On mean maps at the time of 10msec from the QRS initial, the position of the maximum (the greatest positive potential at a certain time point) shifted lower on the anterior chest, and that of the minimum (the greatest negative potential at a certain time point) shifted higher on the back with increasing age. At 30 msec the potential of the maximum decreased on the left anterior chest surface in males, while it increased in females with increasing age. The maximum potential of QRS on each lead (Rmax V) slightly decreased on the antero-superior chest in males, while it clearly increased from the left anterior chest to the left back in females with increasing age. The value of % VC decreased with age in both sexes. These data suggested that the potential of Rmax V was affected by heart size and lung impedance. However in females, changes in the breast might have a greater influence on the changes in Rmax V. The sex difference in Rmax V became smaller with age. The minimum potentials of QRS (Smax V) decreased on the upper anterior chest and back surface. No sex or age differences were found in the ratio of the breakthrough recognition, although the time of the breakthrough tended to increase in both sexes. On ST and T maps, there were few changes with age, but significant sex differences were observed among every age group. These were significant differences in maps between the aged and younger groups. Careful attention should be paid to age and sex differences, when analyzing maps of aged persons. kn-abstract=体表面上に多数の誘導点を設け,それらの各瞬時の電位を求めて等電位線を作成したものが体表面電位図(以下,電位図)である.従来から心起電力を記録する方法として,標準十二誘導心電図やベクトル心電図が臨床上広く用いられているが,標準十二誘導心電図は胸壁上の誘導点が6ヵ所と少いことに問題があり,またベクトル心電図は心起電力を固定した単一双極子であると仮定すること自体にその限界がある.電位図は多数の誘導点を有し心臓の電気現象に関してより多くの情報を得ることができ,また単極誘導心電図から構成されるため,心筋の局所電位の把握にも優れているという特徴を有している.そこで電位図は,虚血性心疾患,心室肥大,心室内伝導傷害部位の同定や心性不整脈の発生源の診断などに応用される様になってきている.ところでわが国は高齢化社会への急激な移行に伴い高齢者の循環器疾患の発症率はますます高くなった.そこで電位図の虚血性心疾患などへの臨床応用が盛んになる中で,まず基礎となる健常高齢者について検討がなされなければならないが,多数の健常高齢者を対象に検討した報告は少なく1),高齢者の心疾患患者の電位図を検討する場合には問題がある.そこで60歳以上の健常高齢者の電位図を,当教室の木村ら2)が報告した60歳未満の健常成人例のそれと比較し,性差,年齢差につき検討した. en-copyright= kn-copyright= en-aut-name=NakaoYou en-aut-sei=Nakao en-aut-mei=You kn-aut-name=中尾陽 kn-aut-sei=中尾 kn-aut-mei=陽 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科学教室 en-keyword=体表面電位図 kn-keyword=体表面電位図 en-keyword=健常高齢者 kn-keyword=健常高齢者 en-keyword=Breakthrough kn-keyword=Breakthrough en-keyword=年齢差 kn-keyword=年齢差 en-keyword=性差 kn-keyword=性差 END start-ver=1.4 cd-journal=joma no-vol=95 cd-vols= no-issue=5-6 article-no= start-page=555 end-page=573 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=19830630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The more desirable surgical procedure in mitral stenosis as based on postoperative left ventricular function and exercise tolerance kn-title=僧帽弁狭窄症の術後左心機能と運動耐容能よりみた至適術式の選択 en-subtitle= kn-subtitle= en-abstract= kn-abstract=There are two major surgical procedures for pure or predominant mitral stenosis, open mitral commissurotomy (OMC) and mitral valve replacement (MVR). The purpose of this study was to assess the left ventricular (LV) function and exercise tolerance after mitral surgery by these procedures. Forty-eight patients underwent mitral valve surgery, and were divided into 3 groups, namely, Sellors type I+II (OMC, 18 patients), Sellors type III (OMC, 13 patients) and Sellors type III (MVR, 17 patients). Bjork-Shiley disc prosthetic valves were used in most of the MVR cases. Although the incidences of the NYHA Class (III+IV) in the Sellors type I+II, Sellors type III and MVR groups were 44.4% , 76.9% and 64.7%, respectively, before surgery, they improved to 0%, 15.4% and 5.9% postoperatively. No remarkable changes in the CI of the Sellors type I+II and Sellors type III groups were recognized through the entire postoperative period, but in the MVR group, both the CI and SVI increased significantly 6 months after the operation compared to preoperative values. The postoperative LV function at rest was best in the Sellors type I+II group (OMC), moderate in the MVR group and worst in the OMC patients of the Sellors type III group. The same results were recognized when scored using the NYHA functional classification. Six months after the operation, both the CI and SVI during exercise markedly decreased in the Sellors type III and MVR groups, and no improvement in the exercise tolerance of either group was recognized. Also, the Heather index increased significantly in comparison with preoperative values. Therefore, improvement in LV contractility and exercise tolerance hoped for in valvular reconstructive surgery was not realized. On the contrary, there was a tendency to become worse at the 6th postoperative month. It is difficult to decide whether to reconstruct or to replace a severely distored mitral valve. Considering the above results, we conclude that OMC of a remarkably distored valve was not necessarily indicated since the possibility of postoperative restenosis and regurgitation is rather high. In light of postoperative LV function and exercise tolerance, MVR seems preferable to OMC. en-copyright= kn-copyright= en-aut-name=MotohiroKatsumi en-aut-sei=Motohiro en-aut-mei=Katsumi kn-aut-name=元廣勝美 kn-aut-sei=元廣 kn-aut-mei=勝美 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第2外科学教室 en-keyword=OMC & MVR kn-keyword=OMC & MVR en-keyword=Impedance cardiography kn-keyword=Impedance cardiography en-keyword=Isometric handgrip exercise kn-keyword=Isometric handgrip exercise en-keyword=左心機能 kn-keyword=左心機能 en-keyword=運動耐容能 kn-keyword=運動耐容能 END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=17 end-page=28 dt-received= dt-revised= dt-accepted= dt-pub-year=1980 dt-pub=19801129 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Influences of the Skin Impedance as the Interface in Bioelectric Potential Measurement en-subtitle= kn-subtitle= en-abstract= kn-abstract=In the case of non-invasive measurement of bioelectric potential from body surface, the influence of the skin impedance has been investigated by using strict equivalent circuits of skin impedances. The relationship between the characteristic of skin impedance and the wave distortion was made clear. Furthermore, in the case of electrocardiograph, the shift potential of indifferent electrode to standard potential was obtained by means of simulation, and the distortions caused by connective resistances of a central terminal and skin impedance were quantitatively explained. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=YamamotoYoshitake kn-aut-sei=Yamamoto kn-aut-mei=Yoshitake aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=YamamotoTatsuma kn-aut-sei=Yamamoto kn-aut-mei=Tatsuma aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical Engineering affil-num=2 en-affil= kn-affil=Department of Electrical Engineering END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=1 article-no= start-page=39 end-page=53 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19791201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Behaviors of a Soliton in Nonlinear L-C Lines with Abrupt Parameter Change en-subtitle= kn-subtitle= en-abstract= kn-abstract=Some behaviors of a lattice soliton in nonlinear L-C ladder lines with abrupt parameter change are investigated. The results of computer and circuit experiments show that in the case of a soliton incident upon the line of larger characteristic impedance and of higher phase velocity in linearized-line-limit, the transmitted wave evolves into larger number of solitons. The experimental results can be well explained by use of both linearization approximation for the line near the junction and the theory by Gardner, Greene, Kruskal and Miura. en-copyright= kn-copyright= en-aut-name=NogiShigeji en-aut-sei=Nogi en-aut-mei=Shigeji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukuiKiyoshi en-aut-sei=Fukui en-aut-mei=Kiyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Electronics affil-num=2 en-affil= kn-affil=Department of Electronics END start-ver=1.4 cd-journal=joma no-vol=3 cd-vols= no-issue=1 article-no= start-page=143 end-page=150 dt-received= dt-revised= dt-accepted= dt-pub-year=1968 dt-pub=19680901 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A Modified Type of the Resonant Turn-off SCR D-C Chopper en-subtitle= kn-subtitle= en-abstract= kn-abstract=A modified type of the resonant turn-off d-c chopprr using an auxiliary SCR, compared with its conventional one, has no limitation about its starting and also operates more steadily. Presented in this paper, making a comparison between the modified type and the conventional one, are the circuit analysis and its efficiency measurement from the point of view of overall efficiency, that is, the ratio of the output to the input. Furthermore, some effects of the source impedance, counter emf load, etc. are discussed. As a result, it has been analytically clarified that this modified type is different from the conventional circuit only by one terminal connection of turn-off capacitor, but has the features of uncompounded circuit configuration, no limitation about its starting and more steady operation. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=HimeiToyoji kn-aut-sei=Himei kn-aut-mei=Toyoji aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=InoueJyunichi kn-aut-sei=Inoue kn-aut-mei=Jyunichi aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=FukumoriKooichi kn-aut-sei=Fukumori kn-aut-mei=Kooichi aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical Engineering affil-num=2 en-affil= kn-affil=Department of Electrical Engineering affil-num=3 en-affil= kn-affil=Department of Electrical Engineering END start-ver=1.4 cd-journal=joma no-vol=23 cd-vols= no-issue=1 article-no= start-page=61 end-page=68 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=19881122 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Determination of Electrical Parameters for Skin during Galvanic Skin Reflex from Continuous Measurement en-subtitle= kn-subtitle= en-abstract= kn-abstract=Skin impedance satisfies the Cole-Cole arc's law. The change of skin impedance during GSR (Galvanic Skin Reflex) can be expressed by the change of equivalent parallel resistance approximately. Using these characteristics, the complicated change of skin impedance during GSR can be determined continuously from the measurement value in one frequency point. en-copyright= kn-copyright= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name=山本尚武 kn-aut-sei=山本 kn-aut-mei=尚武 aut-affil-num=1 ORCID= en-aut-name=YamamotoTatsuma en-aut-sei=Yamamoto en-aut-mei=Tatsuma kn-aut-name=山本辰馬 kn-aut-sei=山本 kn-aut-mei=辰馬 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical and Electronic Engineeringtronic Engineering affil-num=2 en-affil= kn-affil=Department of Electrical and Electronic Engineering END start-ver=1.4 cd-journal=joma no-vol=22 cd-vols= no-issue= article-no= start-page=1 end-page=14 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=19880331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Measurement of Biomechanical Impedance - Its device and measuring conditions en-subtitle= kn-subtitle= en-abstract= kn-abstract=Biomechanical impedance is relatively small compared to industrial mechanical impedance. Thus it is difficult to measure it precisely. A biomechanical impedance measuring system was developed for portable use by means of random excitation. This system doesn't require a fixed body and vibrator supporting apparatus. In order to obtain an impedance spectrum, the FFT processing is performed using a personal computer. The spectra of the biomechanical impedance which is measured on body surfaces depend on body positions and can be roughly classified into three spectra patterns : soft, stiff and intermediate. During the measurement, the measuring conditions (preload, diameter of the vibrating tip etc.) influence the results. However, it became clear that the linearity of the biomechanical impedance was satisfied in the limited measuring conditions. Accordingly it is possible to standardize the impedance and to compare it with the results under different measuring conditions. en-copyright= kn-copyright= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=岡久雄 kn-aut-sei=岡 kn-aut-mei=久雄 aut-affil-num=1 ORCID= en-aut-name=YamamotoTatsuma en-aut-sei=Yamamoto en-aut-mei=Tatsuma kn-aut-name=山本辰馬 kn-aut-sei=山本 kn-aut-mei=辰馬 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical & Electronic Engineering affil-num=2 en-affil= kn-affil=Department of Electrical & Electronic Engineering END start-ver=1.4 cd-journal=joma no-vol=29 cd-vols= no-issue=2 article-no= start-page=39 end-page=47 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19950327 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Correction of Apparent Viscoelasticity of Skin Surface en-subtitle= kn-subtitle= en-abstract= kn-abstract=The body structures under the skin surface, such as bones and tendon, have an influence on the stiffness evaluation observed from the surface. In this case, the observed stiffness should be called an apparent stiffness. To obtain the biomechanical properties of skin itself, the influence of body structure should be removed. This study deals with the correction method of apparent viscoelasticity which calculated from apparent biomechanical impedance. This method is applied to the measured result of the forearm and the right chest to confirm its effectiveness. en-copyright= kn-copyright= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=岡久雄 kn-aut-sei=岡 kn-aut-mei=久雄 aut-affil-num=1 ORCID= en-aut-name=SakamotoShun-ya en-aut-sei=Sakamoto en-aut-mei=Shun-ya kn-aut-name=坂本俊哉 kn-aut-sei=坂本 kn-aut-mei=俊哉 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=IrieTakashi kn-aut-sei=Irie kn-aut-mei=Takashi aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical & Electronic Engineering affil-num=2 en-affil= kn-affil=Department of Electrical & Electronic Engineering affil-num=3 en-affil= kn-affil=Faculty of Education, University of Kochi END start-ver=1.4 cd-journal=joma no-vol=29 cd-vols= no-issue=2 article-no= start-page=29 end-page=37 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19950327 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Estimation of Body Structure by Biomechanical Impedance en-subtitle= kn-subtitle= en-abstract= kn-abstract=In the stiffness evaluation from the skin surface, the body structure under the skin, like a bone and muscle, influences on the measurement results. The authors developed the measurement system of biomechanical impedance with applying a vibration of acoustic frequency onto the body surface. We measured the viscoelasticity of the silicone-gel model, which involves metal blocks, from the gel surface by using this system. The internal structure of model is estimated from the relation between the viscoelasticity and the distance from the gel surface to the internal block. Applying this method, the shape of ribs of the right chest are estimated. The shapes and viscoelasticity of silicone-gel tumor model, which has two different tumors, are also estimated. en-copyright= kn-copyright= en-aut-name=OkaHisao en-aut-sei=Oka en-aut-mei=Hisao kn-aut-name=岡久雄 kn-aut-sei=岡 kn-aut-mei=久雄 aut-affil-num=1 ORCID= en-aut-name=FukudaTakashi en-aut-sei=Fukuda en-aut-mei=Takashi kn-aut-name=福田敬 kn-aut-sei=福田 kn-aut-mei=敬 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Electrical & Electronic Engineering affil-num=2 en-affil= kn-affil=Department of Electrical & Electronic Engineering END start-ver=1.4 cd-journal=joma no-vol=30 cd-vols= no-issue=1 article-no= start-page=19 end-page=24 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19951228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Principle of Biodynamic Analysis Using Human Limb Electrical Impedance en-subtitle= kn-subtitle= en-abstract= kn-abstract=This paper describes a new measurement method and principle of detection of biodynamics using bioelectrical impedance method based on four-electrode technique with sinusoidal constant current. This method uses a human body itself as a part of the sensor. First, we show a bioelectrical impedance measuring device and the change of bioelectrical resistance is measured in human movement. Second, we proposes a principle of detection of biodynamics based on correspondence of magnitude, form and stability of movement to impedance waveform. Hence we can use this method for the judgement of sports skill using the impedance characteristics. en-copyright= kn-copyright= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name=中村隆夫 kn-aut-sei=中村 kn-aut-mei=隆夫 aut-affil-num=1 ORCID= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name=山本尚武 kn-aut-sei=山本 kn-aut-mei=尚武 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=School of Health Sciences affil-num=2 en-affil= kn-affil=Department of Electrical and Electronic Engineering END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue=1 article-no= start-page=53 end-page=62 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20011225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Consideration to the change of swallowing sense after operation of esophagus cancer - Evaluation of swallowing activity by using IPG and swallowing sound - kn-title=食道癌術後の嚥下感覚の変化に対する考察 ―頸部電気インピーダンスおよび嚥下音を用いた嚥下活動評価― en-subtitle= kn-subtitle= en-abstract=The esophagus cancer patient is conscious of passage disorder due to esophagus tumor, to greater or less degrees. Many of patients diagnosed as the esophagus cancer decide to take operation, because they want to come to be able to eat as easily as before they are diagnosed as esophagus cancer. However many patients encounter the change of swallowing sense. In the long run, they must swallow consciously when they eat everything. They are not informed about the change of swallowing sense. Therefore, the patient feels strong anxiety when they noticed about the change. This time, we had an interview about the change of swallowing sense after operation to the patient. In addition, we measured the swallowing activity by using IPG and swallowing sound. As a result, all patients is conscious of the change of swallowing sense. And we noticed the change of IPG wave and the swallowing sound occurred except Pharynx period. So patients want to be informed about the change of swallowing sense strongly before they take operation. And it is necessary for the patient to be informed about the change of swallowing before they take operation. kn-abstract=食道癌患者は腫瘍による狭窄のため,程度の差はあるものの,術前より通過障害を認めることが多い｡食道癌と診断され,手術を自己決定した患者の多くは,手術をして罹患前のように食事ができるようになりたいと思っている｡しかし,患者の多くが術後に嚥下感覚の変化に遭遇する｡現在,手術前に実施されるインフォームドコンセント(以下IC)では,術後に起こる嚥下感覚の変化については説明が行われていない｡そのため患者は,経口摂取が可能になった時点で嚥下感覚の変化を自覚し,強い不安を感じる｡今回, 5人の患者に術後の嚥下感覚の変化に関するインタビューを実施するとともに,術後の嚥下活動を頸部電気インピーダンスおよび嚥下音を用いて測定した｡インタビューの結果, 5人全てが,術後に嚥下感覚の変化を自覚し,不安を感じていた｡また,青年健常者と比較し,IPG波形の多相化と,嚥下音の咽頭期以外での発生が認められた｡患者が,術後に起こる嚥下感覚の変化についてのICを望んでいることからも,術後の嚥下感覚の変化についてのICを行なう必要がある｡ en-copyright= kn-copyright= en-aut-name=MoriKeiko en-aut-sei=Mori en-aut-mei=Keiko kn-aut-name=森恵子 kn-aut-sei=森 kn-aut-mei=恵子 aut-affil-num=1 ORCID= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name=山本尚武 kn-aut-sei=山本 kn-aut-mei=尚武 aut-affil-num=2 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name=中村隆夫 kn-aut-sei=中村 kn-aut-mei=隆夫 aut-affil-num=3 ORCID= en-aut-name=KusuhuraToshimasa en-aut-sei=Kusuhura en-aut-mei=Toshimasa kn-aut-name=楠原俊昌 kn-aut-sei=楠原 kn-aut-mei=俊昌 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科 affil-num=3 en-affil= kn-affil=岡山大学医学部保健学科 affil-num=4 en-affil= kn-affil=岡山大学医学部保健学科 en-keyword=食道癌 (esophagus cancer) kn-keyword=食道癌 (esophagus cancer) en-keyword=嚥下障害 (swallowing disorder) kn-keyword=嚥下障害 (swallowing disorder) en-keyword=生体電気インピーダンス (bioelectrical impedance) kn-keyword=生体電気インピーダンス (bioelectrical impedance) en-keyword=インフォームドコンセント (informed consent) kn-keyword=インフォームドコンセント (informed consent) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=1 end-page=7 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20041215 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Quantitative evaluation method of swallowing hypofunctionby aging using Impedance Pharyngography (IPG) kn-title=インピーダンス咽頭図(IPG)を用いた加齢による嚥下機能減退の定量的評価法 en-subtitle= kn-subtitle= en-abstract=Impedance Pharyngography (IPG) measures neck electrical impedance during swallowing. IPG method is simple procedures and the technique which can perform noninvasive evaluation of swallowing function. IPG waveform reflects swallowing function. However, the influence on IPG waveform by swallowing hypofunction is various by the causes. That is, it will be dependent on a measurement person's subjectivity to compare directly IPG waveforms of subjects whose states of swallowing function differs, and objectivity is missing. kn-abstract=インピーダンス咽頭図(Impedance Pharyngography, 以下IPG)は嚥下活動中の頸部電気インピーダンスを測定するもので,嚥下機能評価を簡便かつ無侵襲に行うことができる手法である｡IPG波形は嚥下機能を反映するものであるが嚥下機能の減退による波形への影響はその原因により様々である｡すなわち嚥下機能の状態が異なる被験者のIPG波形を直接比較･診断することは測定者の主観に依存することになり客観性に欠ける｡本研究では,まず青年健常者のNormal IPGをもとに嚥下機能が反映される波形の特徴を評価するパラメータとして,咽頭通過時間,インピーダンス変化率,類似度,嚥下音タイミングの4つを採用し,IPCを定量的に評価する手法を提案した｡また,この評価法を高齢者のIPGに適用し,青年健常者に比べて嚥下活動に関与する器官が円滑に活動を履行する能力に減退が生じる様子を定量的に示した｡ en-copyright= kn-copyright= en-aut-name=KusuharaToshimasa en-aut-sei=Kusuhara en-aut-mei=Toshimasa kn-aut-name=楠原俊昌 kn-aut-sei=楠原 kn-aut-mei=俊昌 aut-affil-num=1 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name=中村隆夫 kn-aut-sei=中村 kn-aut-mei=隆夫 aut-affil-num=2 ORCID= en-aut-name=MoriKeiko en-aut-sei=Mori en-aut-mei=Keiko kn-aut-name=森恵子 kn-aut-sei=森 kn-aut-mei=恵子 aut-affil-num=3 ORCID= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name=山本尚武 kn-aut-sei=山本 kn-aut-mei=尚武 aut-affil-num=4 ORCID= en-aut-name=ShirakawaYasuhiro en-aut-sei=Shirakawa en-aut-mei=Yasuhiro kn-aut-name=白川靖博 kn-aut-sei=白川 kn-aut-mei=靖博 aut-affil-num=5 ORCID= en-aut-name=NaomotoYoshio en-aut-sei=Naomoto en-aut-mei=Yoshio kn-aut-name=猶本良夫 kn-aut-sei=猶本 kn-aut-mei=良夫 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=3 en-affil= kn-affil=岡山大学医学部保健学科看護学専攻 affil-num=4 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯学総合研究科病態制御科学専攻 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯学総合研究科病態制御科学専攻 en-keyword=嚥下活動 (swallowing) kn-keyword=嚥下活動 (swallowing) en-keyword=嚥下障害 (dysphagia) kn-keyword=嚥下障害 (dysphagia) en-keyword=生体電気インピーダンス (bio-electrical impedance) kn-keyword=生体電気インピーダンス (bio-electrical impedance) en-keyword=インピーダンス咽頭図 (Impedance Pharyngography (IPG)) kn-keyword=インピーダンス咽頭図 (Impedance Pharyngography (IPG)) en-keyword=嚥下機能評価 (assessment of swallowing function) kn-keyword=嚥下機能評価 (assessment of swallowing function) END start-ver=1.4 cd-journal=joma no-vol=17 cd-vols= no-issue=1 article-no= start-page=9 end-page=15 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Electrical Cell-substrate Impedance Sensing (ECIS)法を用いた培養細胞の微細挙動の定量的評価法 - 細胞-細胞間隙と細胞-電極間隙の評価 - kn-title=Quantitative evaluation of micromotion of cultured cells using electrical cell-substrate impedance sensing (ECIS) method - cell-to-cell distance and cell-to-substrate distance - en-subtitle= kn-subtitle= en-abstract=[背景] Electrical Cell-substrate Impedance Sensing (ECIS)は培養細胞の電気的計測により,その微細挙動を評価する工学的手法である｡我々はECISを用いてこの微細挙動を細胞-細胞間隙と細胞-電極間隙に分離して推定することが可能な数学的モデルを提案してきた｡本研究ではこの数学的モデルを使用して,]線を照射した牛大動脈内皮細胞(bovine aortic endothelial cell : BAEC)の微細挙動の経時変化を評価した｡ [方法と結果] ECISシステム(Model 1600R Applied BioPhysics)を用いてBAECのコンフルエント到達前後で計測を行い,数学的モデルを構築した｡このモデルは細胞の微細挙動を検出するために重要な周波数レンジである1-10kHzにおいて測定結果とよく一致し,Cole-Cole円弧則に従う｡さらに細胞-細胞間距離Aの増減に対応する校正定数S(A)と細胞-電極間距離hの増減に対応する校正定数S(h)を導入し,ベクトルインピーダンスの変化に対応した値を算出することで細胞の微細挙動を評価することとした｡次に本法によりX線(150kV, 100Gy)を照射したBAECの微細挙動を評価した｡]線照射細胞では時間経過と共に抵抗成分の変化が支配的なインピーダンスの減少が確認された｡この現象はS(A)の大きな増加とS(h)の微小な減少をもたらした｡このパラメータの変化は細胞間隙が拡大したことを示しており,]線照射による細胞内損傷により細胞密度が低下したと考えられた｡ [結論] 本法は培養細胞の微細動態の変化を細胞-細胞間隙と細胞-電極間隙に分けてリアルタイムに定量評価することが可能であり,各臓器の細胞レベルでの薬物の治療効果や ]線に対する耐性の評価に適応できるものと考える｡ kn-abstract=We have proposed a mathematical model for the micro-dynamics for cultured cells measured with ECIS system for the detection of nanometer-order dynamics of cells cultured on a small gold electrode and could separately evaluate cell-to-cell distance (A) and cell-to-substrate distance (h). For wide applications of this method, we constructed mathematical models which express cell-to-electrode impedances for some kinds of confluent conditions. Based on this mathematical model, we defined new parameters S(A) and S(h) in order to evaluate cell-to-cell distance and cell-to-substrate distance. As the application, we investigated the effect of X-irradiation to bovine aortic endothelial cell (BAEC). We analyzed the micro-dynamics of cells from the impedance of BAEC before and after X-irradiation. It was proved that the stimulation of 100 Gy X-irradiation to the BAEC resulted in the large scale of increase in the cell-to-cell distances (A), and the slight increase in the cell-to-substrate distances (h) accompany with continuous fluctuations. en-copyright= kn-copyright= en-aut-name=GodaNoriko en-aut-sei=Goda en-aut-mei=Noriko kn-aut-name=合田典子 kn-aut-sei=合田 kn-aut-mei=典子 aut-affil-num=1 ORCID= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name=山本尚武 kn-aut-sei=山本 kn-aut-mei=尚武 aut-affil-num=2 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name=中村隆夫 kn-aut-sei=中村 kn-aut-mei=隆夫 aut-affil-num=3 ORCID= en-aut-name=KusuharaToshimasa en-aut-sei=Kusuhara en-aut-mei=Toshimasa kn-aut-name=楠原俊昌 kn-aut-sei=楠原 kn-aut-mei=俊昌 aut-affil-num=4 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科 affil-num=3 en-affil= kn-affil=岡山大学医学部保健学科 affil-num=4 en-affil= kn-affil=岡山大学医学部保健学科 affil-num=5 en-affil= kn-affil=岡山大学医学部保健学科 en-keyword=ECIS method (ECIS法) kn-keyword=ECIS method (ECIS法) en-keyword=bio-electrical impedance (生体インピーダンス) kn-keyword=bio-electrical impedance (生体インピーダンス) en-keyword=cultured cell modeling (細胞培養) kn-keyword=cultured cell modeling (細胞培養) en-keyword=micromotion of cultured cells (細胞微細挙動) kn-keyword=micromotion of cultured cells (細胞微細挙動) en-keyword=X-irradiation (放射線被曝) kn-keyword=X-irradiation (放射線被曝) END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=7-8 article-no= start-page=789 end-page=795 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The relationships between physique and throwing ability in high school baseball players kn-title=高校野球選手における形態と投能力の関係 en-subtitle= kn-subtitle= en-abstract= kn-abstract=There is little information on anthropometric measures (i. e., length, breadth and girth of body's parts) related to throwing ability. To clarify the influence of the physique on the throwing ability, the relationships between physique and throwing distance, as well as ball speed were investigated. The subjects were fourty-nine high school baseball players, and thirty-eight high school volleyball players, football players and canoeists served as a control group. The throwing distance was significantly related to lean body mass (r=.290), chest girth (r=.416), upper arm girth (r=.307), abdominal girth (r=.288), thigh girth (r=.327) and lower leg girth (r=.285) in baseball players group (p<0.05-0.01). A significant relationship between the throwing distance and foot length in control group (r=.329, p<0.05) was demonstrated. Significant relationships between ball speed and standing height in the baseball players group (r=.354, p<0.01) and that between ball speed and Impedance in the control group (r=-.288, p<0.05) were ovserved. These findings indicate that the throwing distance is influenced by quantity of body muscle in baseball players. There was no relation between physique and throwing ability in unskilled players. en-copyright= kn-copyright= en-aut-name=UchidaHayato en-aut-sei=Uchida en-aut-mei=Hayato kn-aut-name=内田勇人 kn-aut-sei=内田 kn-aut-mei=勇人 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学教室 en-keyword=野球選手 kn-keyword=野球選手 en-keyword=形態 kn-keyword=形態 en-keyword=遠投距離 kn-keyword=遠投距離 en-keyword=ボールスピード kn-keyword=ボールスピード en-keyword=Impedance kn-keyword=Impedance END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=225 end-page=240 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Spectrum analysis of arterial blood pressure waveforms kn-title=動脈圧波形の形状変化に対する周波数解析による検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is known that the shape of arterial blood pressure waveform reflects the hemodynamic status, but quantitative analyses of waveform are seldom reported. In this study, the arterial pressure wave was recorded with an intra-arterial catheter and pressure transducer, converted to digital data, and stored in a computer. The data were analyzed by two methods of spectrum analyses, i.e., fast Fourier transform (FFT for both power spectrum and phase information) and the autoregressive model (ARM). Pressure waveforms during normotension were compared with pressure waveforms during hypotension induced by vasodilators (sodium nitroprusside and nitroglycerin) in the human study, and by the vasodilators, hemorrhage or 3% isoflurane in the animal study. Reconstruction of waveforms by inverse FFT was also performed, and compared with the original waveforms. FFT is more useful than ARM for analysis of data with known frequencies, such as respiratory and heart rates. Using inverse FFT, the wave can be reconstructed by the base frequency (heart rate) to 4th harmonic data with an error margin of less than 2%. The amplitude and phase information of heart rate frequency up to its 4th harmonic, and amplitude of respiratory frequency, were found to be the essential parameters to describe the shape of the arterial pressure waveform. en-copyright= kn-copyright= en-aut-name=SaitoTomohiko en-aut-sei=Saito en-aut-mei=Tomohiko kn-aut-name=齋藤智彦 kn-aut-sei=齋藤 kn-aut-mei=智彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部麻酔・蘇生学教室 en-keyword=動脈圧波形 kn-keyword=動脈圧波形 en-keyword=周波数解析 kn-keyword=周波数解析 en-keyword=フーリエ変換 kn-keyword=フーリエ変換 en-keyword=自己回帰モデル kn-keyword=自己回帰モデル END start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue= article-no= start-page=23 end-page=28 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Percentage body fat and results of a periodic health examination kn-title=体脂肪率と定期健康診断成績 en-subtitle= kn-subtitle= en-abstract=Data from periodic health examinations such as ALP, UA, RBC, Hb, SGOT, SGPT, Tch(total choresterol), TG(triglyceride), blood pressure, body length, body weight and also percentage body fat(% Fat) as measured by bioelectrical impedance mehtod were obtained from 235 male and 137 female workers at a brewery factory in Okayama Prefecture and results were analyzed. The correlation coefficients for % Fat and Body Mass Index values(BMI) are found to be 0.678 for males and 0.803 for females. Examinees were then devided into normal and obesity groups respectively, and the frequency of values over normal ranges (classified by obesity indicators such as % Fat, BMI and obesity rate calculated from standard weight) were statistically compared. Results showed that % Fat and BMI were more sensitive than obesity rate and that the obesity group had statistically high frequencies of abnormality in some of the data as in the case of SGPT, γGTP and TG compared to the control group. Furthermore this tendency was found to be more significant among male workers than female ones. kn-abstract=肥満や栄養過剰は多くの慢性疾患、とりわけ成人病と関連が強いことが従来から指摘されている。肥満の判定には体脂肪率を測定することが重要であるが、その方法の一つとして、集団検診に使用しやすい生体電気インピーダンス法（bioelectrical impedance analysis）がある。今回、1ビール製造工場の定期健康診断において、対象者男235人および女137人の体脂肪率をこの方法により測定した。まずこの体脂肪率とBMIおよび肥満度との相関関係を求め、男性より女性において相関が高いことを認めた。ついで肥満群と正常群に分けて、血圧および血液検査の異常率の出現頻度を統計的に比較したところ、肥満群では男女共に総コレステロールで、また男性では尿酸、γGTP、SGPTの各値で、異常者が高率であることを認めた。またSGPTは30才台から、γGTP及びTchは40才台からその傾向が見られた。しかし、肥満指数とこれらの検査値との相関係数は高くはなかった。 en-copyright= kn-copyright= en-aut-name=OhtaTakeo en-aut-sei=Ohta en-aut-mei=Takeo kn-aut-name=太田武夫 kn-aut-sei=太田 kn-aut-mei=武夫 aut-affil-num=1 ORCID= en-aut-name=GotoAkio en-aut-sei=Goto en-aut-mei=Akio kn-aut-name=後藤彰夫 kn-aut-sei=後藤 kn-aut-mei=彰夫 aut-affil-num=2 ORCID= en-aut-name=MasakiHisako en-aut-sei=Masaki en-aut-mei=Hisako kn-aut-name=正木久子 kn-aut-sei=正木 kn-aut-mei=久子 aut-affil-num=3 ORCID= en-aut-name=TakamiYoko en-aut-sei=Takami en-aut-mei=Yoko kn-aut-name=高見陽子 kn-aut-sei=高見 kn-aut-mei=陽子 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療技術短期大学部看護学科 affil-num=2 en-affil= kn-affil=倉敷成人病健診センター affil-num=3 en-affil= kn-affil=倉敷成人病健診センター affil-num=4 en-affil= kn-affil=キリンビール岡山工場健康管理室 en-keyword=体脂肪率 (percentage body fat) kn-keyword=体脂肪率 (percentage body fat) en-keyword=インピーダンス (bioelectorical impedance) kn-keyword=インピーダンス (bioelectorical impedance) en-keyword=BIA kn-keyword=BIA en-keyword=健康診断 (periodic health examination) kn-keyword=健康診断 (periodic health examination) en-keyword=BMI kn-keyword=BMI END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue=2 article-no= start-page=107 end-page=115 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=生体電気信号の計測システムへの電力線からの誘導障害に関するインターフェイスモデル kn-title=Modelling of interface construction relating to power-line interference phenomenon in biopotential signal measurement system en-subtitle= kn-subtitle= en-abstract=生体電気信号の測定における電力線からの誘導障害についての研究が多く報告されているが，この現象についての説明が十分なされていなかった。本研究では，この現象を簡単なインターフェイスモデルを用いて説明した。誘導障害の原因として，電極の導線が作るループ内に発生する誘導起電力，システムの変位電流，生体アンプ内で発生する雑音等があげられる。本研究においては，電力線と導線との静電結合によってその間を流れる変位電流と被験者と電極間のインピーダンスに注目した。この変位電流による誘導は，いくつかの要素に依存している。それらは，・被験者と電力線との距離，・被験者に対する電力線の方向，・導線のシールドされていない部分の長さ，・被験者と電極間のインピーダンスである。そこで，被験者と電力線との距離や導線のシールドされていない部分の長さなどを変化させて，心電図の測定を行った。被験者と電極間のインピーダンスを調整できるように，可変抵抗を用いたRC並列回路をそれぞれの導線に直列に接続した。また，導線のループに発生する誘導起電力をできるだけ小さくするために，導線を互いに撚ってループ面積を小さくした。誘導雑音は，以下の場合に大きくなった。・電力線の距離が近い。・導線のシールドされてない部分が長い。・被験者と電極間のインピーダンスが大きく，不均衡である。また，被験者と電極間のインピーダンスを等しくした場合でも，誘導雑音が観測された。電力線の位置により各導線と電力線との静電結合状態が異なり，各導線に流れる変位電流が等しくないことが誘導雑音の原因であることを示した。本研究では被験者と電極間のインピーダンスおよび変位電流による誘導雑音の影響について検討した。この現象の理解は誘導障害の除去に大変有益なものである。 kn-abstract=A modelling of interface construction relating to power-line interference phenomenon was described. Source of interference was displacement currents which flowed from AC power-line configuration (APC) to a model. The interference depends on some factors: distance between the APC and a model ; length of unshielded leads ; position of the APC in vertical or horizontal direction ; and skin-electrode impedances which were balance or unbalanced. The position of APC and skin-electrode impedances were important in contributing of the interference. The interference was still large even though skin-electrode impedances were balance. This was caused by the disagreement in two displacement currents. It was overcame by adjustment of APC in vertical direction. As a result, total interference would be very small or zero. The result shows that interference in ECG signal recording can be eliminated to about 10 μV. Although interference of power-lines is a complicated phenomenon, the problem is easier to understand by using this modelling. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=Adli kn-aut-sei=Adli kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name=山本尚武 kn-aut-sei=山本 kn-aut-mei=尚武 aut-affil-num=2 ORCID= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name=中村隆夫 kn-aut-sei=中村 kn-aut-mei=隆夫 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=3 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 en-keyword=AC power-line configuration (APC) (電力線配置) kn-keyword=AC power-line configuration (APC) (電力線配置) en-keyword=biopotential signal (生体電気信号) kn-keyword=biopotential signal (生体電気信号) en-keyword=displacement current (変位電流) kn-keyword=displacement current (変位電流) en-keyword=physical model of interference (モデル) kn-keyword=physical model of interference (モデル) en-keyword=power-line interference (誘導障害) kn-keyword=power-line interference (誘導障害) END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue=1 article-no= start-page=15 end-page=22 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19991220 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Variations of parameters of bioelectrical impedance during upper limb movement kn-title=上肢運動に伴う生体電気インピーダンスのパラメータの変動 en-subtitle= kn-subtitle= en-abstract=We have proposed new biodynamic analysis methods using bioelectrical impedance. Variations of human limb electrical impedance during biodynamics were caused by variations of equivalent cross sectional area of muscle and variations of blood volume. However these variations could not be directly measured. Therefore quantitative discussions about relation between the impedance and these variations have been insufficient. In this work, we explained variations of the impedance with variations of parameters of an equivalent circuit. The model of impedance was Cole-Cole type. The equivalent circuit consisted of five individual parameters as follows : extracellular fluid resistance, 'Re', intracellular fluid resistance, 'Ri', characteristic frequency of dispersion, 'fm' and parameters of dispersion of relaxation time, 'α' and 'β'. Impedances of forearm and upper arm were measured with four electrode method during flexion and extension of joints in upper limb. The ratio of variations of equivalent series resistance R was linear-approximated using the above mentioned parameters. The influences of parameters on variations of R was confirmed. R was strongly influenced by Re and Ri, However there were differences between influence of Re and that of Ri in difference measured part and difference joint movement. This showed the conditibn of the muscle. In case of the maximum flexion of the elbow joint, R of upper arm was influenced by fm. This means that a polarization of cell membrane changes and influences impedance during movement. These results are significant in evaluation of biodynamics including difference of strength of movement and condition of exhaustion. kn-abstract=これまでに生体電気インピーダンスを用いて身体運動の解析を行ってきた。インピーダンスの変動原因は測定部位の等価断面積変化および貯血量変化と説明できるが，直接的に断面積変化や貯血量変化を測定することは困難であるため，その変動原因の定量的な検討は不十分であった。そこで，本研究では上肢運動に伴う生体電気インピーダンスの変動原因を生体の等価回路のパラメータの変動で説明する。インピーダンスのモデルはCole−Cole型であり，等価回路は，細胞外液抵抗Re，細胞内液抵抗Ri，分散の特性周波fm fm，緩和時間の分布の程度を表すα，βの独立した5パラメータで表現した。 上肢の肘関節および手関節の屈曲運動野に伴う前腕部および上腕部の電気インピーダンスを測定した。まず，電気インピーダンスの等価直列抵抗Rの変動率をパラメータの変動率で線形近似し，その信頼性と各パラメータ変動のRへの影響を確認した。Rへの影響はReとRiが支配的であるが，測定部位や運動の違いにより，それぞれの影響が異なることを示した。これは測定部位の筋活動状態の違いを表すものである。さらに，肘関節最大屈曲におけるRの変化にはfmの変化が大きく依存しており，上肢運動のインピーダンス変化には細胞膜の分極特性の変化も影響していることを明らかにした。本研究の結果は，運動強度の違いや疲労状態における身体運動評価に有意義である。 en-copyright= kn-copyright= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name=中村隆夫 kn-aut-sei=中村 kn-aut-mei=隆夫 aut-affil-num=1 ORCID= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name=山本尚武 kn-aut-sei=山本 kn-aut-mei=尚武 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 en-keyword=生体電気インピーダンス (bioelectrical impedance) kn-keyword=生体電気インピーダンス (bioelectrical impedance) en-keyword=等価回路 (equivalent circuit) kn-keyword=等価回路 (equivalent circuit) en-keyword=Cole-Cole円弧 (Cole-Cole circular loci) kn-keyword=Cole-Cole円弧 (Cole-Cole circular loci) en-keyword=上肢運動 (upper limb movement) kn-keyword=上肢運動 (upper limb movement) en-keyword=4電極法 (four electrode method) kn-keyword=4電極法 (four electrode method) END start-ver=1.4 cd-journal=joma no-vol=11 cd-vols= no-issue=2 article-no= start-page=65 end-page=70 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relationships between electrical impedance and light transmission of flowing blood kn-title=流動血液の電気インピーダンスと透過光強度との関係 en-subtitle= kn-subtitle= en-abstract=The purpose of this study was to investigate the characteristics of light transmission and electrical impedance of flowing blood in an artificial vessel including stenosis. The artificial blood vessel consisted of a rigid flow-through model. The method of impedance measurement used the four-electrodes technique based on sinusoidal.current (10 kHz). Light (940 nm) was guided to the model by an optical fiber and transmitted light and was picked up by a similar fiber on the opposite side. Relative change in light transmission and electrical impedance decreased with increasing blood flow in general. But the relative change in light transmission and electrical impedance varied differently comparing measurements close to the stenosis and at different distances from the stenosis. kn-abstract=流動する血液についての力学的，光学的および電気的な特性についての研究が数多く報告されている。本研究では，狭窄がある人工血管を流れる血液の電気インピーダンス（周波数10kHz）を近赤外光（波長940nm）の透過度と同時に測定し，血液の電気インピーダンスの特性について検討を行った。内径2mmのアクリル製の血管モデルを作製し，その内部に断面積の小さい狭窄部位を1ヵ所設置し，ヒトの血液（Hct40％）を流した。定常流においては血流速度の増加に伴いインピーダンスの相対変化量および透過光強度ともに減少した。しかし，狭窄部に近い部位では，インピーダンスと透過光強度の変化パターンに違いがみられた。インピーダンスおよび透過光強度は流動する血球の動きや配向等を反映していると考えられた。 en-copyright= kn-copyright= en-aut-name=NakamuraTakao en-aut-sei=Nakamura en-aut-mei=Takao kn-aut-name=中村隆夫 kn-aut-sei=中村 kn-aut-mei=隆夫 aut-affil-num=1 ORCID= en-aut-name=YamamotoYoshitake en-aut-sei=Yamamoto en-aut-mei=Yoshitake kn-aut-name=山本尚武 kn-aut-sei=山本 kn-aut-mei=尚武 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 affil-num=2 en-affil= kn-affil=岡山大学医学部保健学科放射線技術科学専攻 en-keyword=流動血液 (flowing blood) kn-keyword=流動血液 (flowing blood) en-keyword=生体電気インピーダンス (bioelectrical impedance) kn-keyword=生体電気インピーダンス (bioelectrical impedance) en-keyword=定常流 (steady flow) kn-keyword=定常流 (steady flow) en-keyword=拍動流 (pulsatile flow) kn-keyword=拍動流 (pulsatile flow) en-keyword=透過光強度 (light transmission) kn-keyword=透過光強度 (light transmission) END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=数理モデルを用いた細胞電気インピーダンス計測(ECIS)法における血管内皮細胞の微細動態の解析 kn-title=Evaluation of micromotion of vascular endothelial cells in electrical cell-substrate impedance sensing (ECIS) method using a mathematical model en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=GodaNoriko en-aut-sei=Goda en-aut-mei=Noriko kn-aut-name=合田典子 kn-aut-sei=合田 kn-aut-mei=典子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1976 dt-pub=19761231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=segmental impedance plethysmographyによる下腿の非観血的血流測定法 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=土光荘六 kn-aut-sei=土光 kn-aut-mei=荘六 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=83 cd-vols= no-issue=1 article-no= start-page=27 end-page=34 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=1994 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An Exemplifying Study on Graveyard Removal in an Agricultural Land Consolidation Project kn-title=圃場整備における墓地移転の事例的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=To modernize agricultural and rural areas, what is needed is not only infrastructure Improvement which enables mechanized farming, but also comprehensive improvement of inhabited areas. An agricultural land consolidation project should be planned to solve Both of these problems. Recently, in view of more effective land use, a larger scale land consolidation is orientated. In planning the project, houses and graveyards present here and there in the project area sometimes hinder ideal allocation of roads, channels and fields. Therefore, it is crucial in order for rational Planning, to obtain lots for non-agricultural use which enable those impeding objects to be shifted. One of the most feasible ways to obtain the lots is by making use of converted substitute lots in the process of the land consolidation project. In particular, removal of graveyards and reuse of former graveyard sites is sometimes Very difficult to handle, because they are subject to religious restrictions. In this paper, The authors investigated old customs and religious backgrounds of the graveyards in the Research area. Then they investigated the examples of successful treatment of the Converted substitute lots in shifting the graveyards. en-copyright= kn-copyright= en-aut-name=NagahoriKinzo en-aut-sei=Nagahori en-aut-mei=Kinzo kn-aut-name=長堀金造 kn-aut-sei=長堀 kn-aut-mei=金造 aut-affil-num=1 ORCID= en-aut-name=AkaeTakeo en-aut-sei=Akae en-aut-mei=Takeo kn-aut-name=赤江剛夫 kn-aut-sei=赤江 kn-aut-mei=剛夫 aut-affil-num=2 ORCID= en-aut-name=OhtaSeiroku en-aut-sei=Ohta en-aut-mei=Seiroku kn-aut-name=大田征六 kn-aut-sei=大田 kn-aut-mei=征六 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 en-keyword=圃場整備 kn-keyword=圃場整備 en-keyword=墓地移転 kn-keyword=墓地移転 END