検索結果 - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Role of Cytoreductive Nephrectomy in the Immune Checkpoint Inhibitor Era: A Multicenter Collaborative Study

FullText URL	fulltext.pdf
Author	Nukaya, Takuhisa\| Takahara, Kiyoshi\| Toyoda, Shingo\| Inoki, Lan\| Fukuokaya, Wataru\| Mori, Keiichiro\| Iwata, Takehiro\| Bekku, Kensuke\| Maenosono, Ryoichi\| Tsujino, Takuya\| Hirasawa, Yosuke\| Yanagisawa, Takafumi\| Hashimoto, Takeshi\| Komura, Kazumasa\| Araki, Motoo\| Fujita, Kazutoshi\| Ohno, Yoshio\| Shiroki, Ryoichi\|
Keywords	cytoreductive nephrectomy IMDC classification immune checkpoint inhibitor neutrophil-to- lymphocyte ratio sarcomatoid differentiation
Published Date	2025-08-19
Publication Title	International Journal of Urology
Volume	volume32
Issue	issue11
Publisher	Wiley
Start Page	1677
End Page	1685
ISSN	0919-8172
NCID	AA11042471
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	40831087
DOI	10.1111/iju.70207
Web of Science KeyUT	001610691000032
Related Url	isVersionOf https://doi.org/10.1111/iju.70207

The significance of adding posterior decompression to spine stabilization in metastatic spinal surgery: a multicenter prospective study

FullText URL	fulltext.pdf suppl1.docx suppl2.docx suppl3.docx suppl4.docx suppl5.docx
Author	Tominaga, Hiroyuki\| Kawamura, Ichiro\| Shimada, Hirofumi\| Sasaki, Hiromi\| Taniguchi, Noboru\| Shiratani, Yuki\| Suzuki, Akinobu\| Terai, Hidetomi\| Shimizu, Takaki\| Kakutani, Kenichiro\| Kanda, Yutaro\| Ishihara, Masayuki\| Paku, Masaaki\| Takahashi, Yohei\| Funayama, Toru\| Miura, Kousei\| Shirasawa, Eiki\| Inoue, Hirokazu\| Kimura, Atsushi\| Iimura, Takuya\| Moridaira, Hiroshi\| Nakajima, Hideaki\| Watanabe, Shuji\| Akeda, Koji\| Takegami, Norihiko\| Nakanishi, Kazuo\| Sawada, Hirokatsu\| Matsumoto, Koji\| Funaba, Masahiro\| Suzuki, Hidenori\| Funao, Haruki\| Oshigiri, Tsutomu\| Hirai, Takashi\| Otsuki, Bungo\| Kobayakawa, Kazu\| Uotani, Koji\| Manabe, Hiroaki\| Tanishima, Shinji\| Hashimoto, Ko\| Iwai, Chizuo\| Yamabe, Daisuke\| Hiyama, Akihiko\| Seki, Shoji\| Goto, Yuta\| Miyazaki, Masashi\| Watanabe, Kazuyuki\| Nakamae, Toshio\| Kaito, Takashi\| Nakashima, Hiroaki\| Nagoshi, Narihito\| Kato, Satoshi\| Imagama, Shiro\| Watanabe, Kota\| Inoue, Gen\| Furuya, Takeo\|
Keywords	Metastatic spinal tumors Spine stabilization Decompression Propensity score matching Multicenter prospective study The epidural spinal cord compression (ESCC) score
Published Date	2025-07-29
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	27684
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40730859
DOI	10.1038/s41598-025-12485-7
Web of Science KeyUT	001539909400020
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-12485-7

Effectiveness of Statins for Oxaliplatin‐Induced Peripheral Neuropathy: A Multicenter Retrospective Observational Study

FullText URL	fulltext.pdf suppl1.docx suppl2.docx suppl3.docx
Author	Takechi, Kenshi\| Kawashiri, Takehiro\| Mine, Keisuke\| Ushio, Soichiro\| Hamano, Hirofumi\| Hida, Noriko\| Momo, Kenji\| Uchiyama, Masanobu\| Uchida, Mami\| Tanaka, Mamoru\| Hidaka, Noriaki\| Yasui, Hideki\| Ueda, Masahiro\| Fujii, Ryohei\| Hashimoto, Misaki\| Sakamoto, Yasutaka\| Uyama, Kana\| Niimura, Takahiro\| Hanai, Yuki\| Tsuboya, Ayaka\| Suzuki, Keisuke\| Kamiyama, Naoya\| Hagiwara, Hiromi\| Okada, Naoto\| Zamami, Yoshito\| Ishizawa, Keisuke\|
Keywords	cancer colorectal cancer oxaliplatin peripheral neuropathy statins
Published Date	2025-09-29
Publication Title	Clinical and Translational Science
Volume	volume18
Issue	issue10
Publisher	Wiley
Start Page	e70318
ISSN	1752-8054
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	41021349
DOI	10.1111/cts.70318
Web of Science KeyUT	001582996800001
Related Url	isVersionOf https://doi.org/10.1111/cts.70318

Vanishing White Matter Disease With EIF2B2 c.254T >A Variant

FullText URL	fulltext.pdf suppl.pdf
Author	Kakumoto, Toshiyuki\| Matsukawa, Takashi\| Tokimura, Ryo\| Tsuboyama, Yoko\| Hayashi, Yasufumi\| Mitsutake, Akihiko\| Iwata, Atsushi\| Maeda, Meiko Hashimoto\| Shimizu, Jun\| Gonoi, Wataru\| Ishiura, Hiroyuki\| Mitsui, Jun\| Tsuji, Shoji\| Toda, Tatsushi\|
Published Date	2025-10
Publication Title	Neurology Genetics
Volume	volume11
Issue	issue5
Publisher	Ovid Technologies (Wolters Kluwer Health)
Start Page	e200293
ISSN	2376-7839
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	40900972
DOI	10.1212/nxg.0000000000200293
Related Url	isVersionOf https://doi.org/10.1212/nxg.0000000000200293

Can online interactions reduce loneliness in young adults during university closures in Japan? The directed acyclic graphs approach

FullText URL	fulltext.pdf suppl1.docx suppl2.docx
Author	Kambara, Kohei\| Toya, Akihiro\| Lee, Sumin\| Shimizu, Haruka\| Abe, Kazuaki\| Shigematsu, Jun\| Zhang, Qingyuan\| Abe, Natsuki\| Hayase, Ryo\| Abe, Nobuhito\| Nakai, Ryusuke\| Aoki, Shuntaro\| Asano, Kohei\| Asano, Ryosuke\| Fujimura, Makoto\| Fukui, Ken’ichiro\| Fukumoto, Yoshihiro\| Furutani, Kaichiro\| Hasegawa, Koji\| Hashimoto, Hirofumi\| Hashimoto, Mikoto\| Hosogoshi, Hiroki\| Ikeda, Hiroshi\| Ishioka, Toshiyuki\| Ito, Chiharu\| Iwano, Suguru\| Kamada, Masafumi\| Kanai, Yoshihiro\| Karita, Tomonori\| Kasagi, Yu\| Kashima, Emiko S.\| Kato, Juri\| Kawachi, Yousuke\| Kawahara, Jun‐ichiro\| Kimura, Masanori\| Kira, Yugo\| Kiyonaga (Sakoda), Yuko\| Kohguchi, Hiroshi\| Komiya, Asuka\| Masui, Keita\| Midorikawa, Akira\| Mifune, Nobuhiro\| Mizukoshi, Akimine\| Nawata, Kengo\| Nishimura, Takashi\| Nogiwa, Daisuke\| Ogawa, Kenji\| Okada, Junko\| Okamoto, Aki\| Okamoto, Reiko\| Sasaki, Kyoko\| Sato, Kosuke\| Shimizu, Hiroshi\| Sugimura, Atsushi\| Sugitani, Yoko\| Sugiura, Hitomi\| Sumioka, Kyoko\| Sunaguchi, Bumpei\| Takebe, Masataka\| Tanabe, Hiroki C.\| Tanaka, Ayumi\| Tanaka, Masanori\| Taniguchi, Junichi\| Tokunaga, Namiji\| Tomita, Ryozo\| Ueda, Yumiko\| Yamashita, Tomomi\| Yamaura, Kazuho\| Yogo, Masao\| Yokotani, Kenji\| Yoshida, Ayano\| Yoshida, Hiroaki\| Yoshihara, Katsue\| Yoshikawa, Ayumi\| Yanagisawa, Kuniaki\| Nakashima, Ken'ichiro\|
Keywords	directed acyclic graphs loneliness online interactions psychological network university closures university students
Published Date	2024-12-12
Publication Title	Asian Journal of Social Psychology
Volume	volume28
Issue	issue1
Publisher	Wiley
Start Page	e12658
ISSN	1367-2223
NCID	AA11235034
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Author(s).
File Version	publisher
DOI	10.1111/ajsp.12658
Web of Science KeyUT	001414019400001
Related Url	isVersionOf https://doi.org/10.1111/ajsp.12658

Heart failure-specific cardiac fibroblasts contribute to cardiac dysfunction via the MYC–CXCL1–CXCR2 axis

FullText URL	fulltext.pdf suppl1.pdf suppl2.xlsx
Author	Komuro, Jin\| Hashimoto, Hisayuki\| Katsuki, Toshiomi\| Kusumoto, Dai\| Katoh, Manami\| Ko, Toshiyuki\| Ito, Masamichi\| Katagiri, Mikako\| Kubota, Masayuki\| Yamada, Shintaro\| Nakamura, Takahiro\| Akiba, Yohei\| Kouka, Thukaa\| Komuro, Kaoruko\| Kimura, Mai\| Ito, Shogo\| Nomura, Seitaro\| Komuro, Issei\| Fukuda, Keiichi\| Yuasa, Shinsuke\| Ieda, Masaki\|
Published Date	2025-09-10
Publication Title	Nature Cardiovascular Research
Volume	volume4
Issue	issue9
Publisher	Springer Science and Business Media LLC
Start Page	1135
End Page	1151
ISSN	2731-0590
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40931092
DOI	10.1038/s44161-025-00698-y
Web of Science KeyUT	001567654900001
Related Url	isVersionOf https://doi.org/10.1038/s44161-025-00698-y

Metaverse Support Groups for LGBTQ+ Youth: An Observational Study on Safety, Self-Expression, and Early Intervention

FullText URL	fulltext.pdf
Author	Hasei, Joe\| Matsumoto, Yosuke\| Kawai, Hiroki\| Okahisa, Yuko\| Takaki, Manabu\| Ozaki, Toshifumi\|
Keywords	LGBTQ+ Youth Social Isolation Suicide Prevention Avatar-Based Interventions
Published Date	2025-06-02
Publication Title	Journal of Metaverse
Volume	volume5
Issue	issue2
Publisher	Izmir Akademi Dernegi
Start Page	156
End Page	167
ISSN	2792-0232
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
DOI	10.57019/jmv.1639701
Related Url	isVersionOf https://doi.org/10.57019/jmv.1639701

Fan-Shaped Pneumatic Soft Actuator that Can Operate Bending Motion for Ankle-Joint Rehabilitation Device

FullText URL	fulltext.pdf
Author	Shimooka, So\| Yokoya, Hirosato\| Hamada, Masanori\| Shiomi, Shun\| Uehara, Takenori\| Hirayama, Takahiro\| Kamegawa, Tetsushi\|
Keywords	fan-shaped pneumatic soft actuator ankle-joint rehabilitation device hysteresis range of motion
Published Date	2025-02-20
Publication Title	Journal of Robotics and Mechatronics
Volume	volume37
Issue	issue1
Publisher	Fuji Technology Press Ltd.
Start Page	43
End Page	53
ISSN	1883-8049
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Fuji Technology Press Ltd.
File Version	publisher
DOI	10.20965/jrm.2025.p0043
CRID	1390584729933353728
Web of Science KeyUT	001460470700001
Related Url	isVersionOf https://doi.org/10.20965/jrm.2025.p0043

Activated factor X inhibition ameliorates NF-κB-IL-6-mediated perivascular inflammation and pulmonary hypertension

FullText URL	fulltext.pdf
Author	Imakiire, Satomi\| Kimuro, Keiji\| Yoshida, Keimei\| Masaki, Kohei\| Izumi, Ryo\| Imabayashi, Misaki\| Watanabe, Takanori\| Ishikawa, Tomohito\| Hosokawa, Kazuya\| Matsushima, Shouji\| Hashimoto, Toru\| Shinohara, Keisuke\| Katsuki, Shunsuke\| Matoba, Tetsuya\| Nakamura, Kazufumi\| Hirano, Katsuya\| Tsutsui, Hiroyuki\| Abe, Kohtaro\|
Keywords	factor Xa IL-6 proteinase-activated receptor pulmonary arterial hypertension pulmonary hypertension
Published Date	2025-07-01
Publication Title	American Journal of Physiology-Lung Cellular and Molecular Physiology
Volume	volume329
Issue	issue1
Publisher	American Physiological Society
Start Page	L183
End Page	L196
ISSN	1040-0605
NCID	AA10700616
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Authors.
File Version	publisher
PubMed ID	40514194
DOI	10.1152/ajplung.00303.2024
Web of Science KeyUT	001526633800001
Related Url	isVersionOf https://doi.org/10.1152/ajplung.00303.2024

Mimicking Contralateral Pneumothorax during Thoracoscopic Bullectomy Associated with Intraoperative Hyperinflation of a Large Bulla in an Obese Patient

JaLCDOI	10.18926/AMO/69159
FullText URL	79_4_311.pdf
Author	Matsubara, Kei\| Matsubara, Kei\| Hirano, Yutaka\| Fujiwara, Toshiya\|
Abstract	A 55-year-old obese Japanese male with left pneumothorax presented to our hospital. Bilateral pulmonary emphysema was confirmed. Persistent air leakage was observed, and a thoracoscopic bullectomy was performed. Although the thoracoscopic bullectomy was completed uneventfully, pre-extubation chest X-ray imaging indicated hyper-lucency occupying the right upper part of the thoracic cavity, suggesting right-sided pneumothorax. CT imaging indicated a right-upper-lobe expanded bulla. Extubation was performed, and the hyperinflated bulla gradually deflated. Careful management of bulla expansion and respiratory status may be necessary for patients with obesity and large bullae, especially in one-lung ventilation cases.
Keywords	giant bulla pneumothorax obesity positive pressure ventilation one lung ventilation
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2025-08
Volume	volume79
Issue	issue4
Publisher	Okayama University Medical School
Start Page	311
End Page	315
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2025 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	40859450
Web of Science KeyUT	001566281000001

Outcome of Decompression Surgery Following Rapid Neurological Deterioration in Patients with Spinal Cord Injury Without Radiographic Evidence of Trauma (SCIWORET)

JaLCDOI	10.18926/AMO/69151
FullText URL	79_4_261.pdf
Author	Hirata, Yuichi\| Sugahara, Chiaki\| Sasada, Susumu\| Miyake, Hayato\| Nagase, Takayuki\| Yasuhara, Takao\| Tanaka, Shota\|
Abstract	Cervical spondylotic myelopathy (CSM) and ossification of the posterior longitudinal ligament (OPLL) increase the likelihood of spinal cord injury without radiographic evidence of trauma (SCIWORET). Opinions regarding the optimal timing for surgery in such cases vary, however. We retrospectively investigated the demographics and outcomes of patients with SCIWORET who underwent surgery shortly after experiencing rapid neurological deterioration, and we matched patients who underwent standby surgery for CSM or OPLL. Although the optimal timing of surgery for SCIWORET remains unclear, our findings suggest that early stage surgery for SCIWORET may yield favorable neurological improvements.
Keywords	spinal trauma SCIWORET timing of surgery cervical spondylotic myelopathy ossification of the posterior longitudinal ligament
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2025-08
Volume	volume79
Issue	issue4
Publisher	Okayama University Medical School
Start Page	261
End Page	267
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2025 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	40859442
Web of Science KeyUT	001566286400005

A Study of Periprosthetic Femoral Stem Fractures in Hip Arthroplasty for Femoral Neck Fracture

JaLCDOI	10.18926/AMO/69150
FullText URL	79_4_253.pdf
Author	Miyake, Yoshiaki\| Takagi, Toru\| Konishiike, Taizo\|
Abstract	This study investigated the risk factors for bone fragility and perioperative periprosthetic femoral stem fractures in patients undergoing hip arthroplasty for femoral neck fractures. The records of 215 patients (42 male, 173 female; mean age, 84.4 years) were analyzed to assess correlations among periprosthetic fracture rates and sex, age, body mass index (BMI), Dorr classification, femoral stem fixation type (cemented/cementless), and bone mineral density (BMD) of the contralateral proximal femur. The overall prevalence of perioperative periprosthetic fractures was 4.7%. All patients with periprosthetic fractures were female, and all but one were ≥ 80 years of age. Fracture rates were higher in patients with lower BMI, although this difference was not significant. The fracture rates were 0%, 4.7%, and 7.9% for Dorr types A, B, and C, respectively, and 0% and 5.3% for patients who received cemented and cementless stems, respectively. The findings indicated that female patients, those of advanced age, those with lower BMI, and those with Dorr type C had lower BMDs. Although BMD was significantly lower in patients who received cemented stems compared to those who received cementless stems, no fractures were observed in the former group, suggesting that the use of cemented stems is safe for this high-risk population.
Keywords	bone mineral density cemented stem Dorr classification femoral neck fracture periprosthetic femoral stem fracture
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2025-08
Volume	volume79
Issue	issue4
Publisher	Okayama University Medical School
Start Page	253
End Page	259
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2025 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	40859441
Web of Science KeyUT	001566286400004

A Preliminary Survey of Rheumatologists on the Management of Late-onset Rheumatoid Arthritis in Japan

FullText URL	fulltext.pdf suppl1.tif suppl2.pdf suppl3.pdf
Author	Takanashi, Satoshi\| Kaneko, Yuko\| Kawahito, Yutaka\| Kida, Takashi\| Sugihara, Takahiko\| Kojima, Toshihisa\| Harada, Ryozo\| Ishitoku, Michinori\| Hirata, Shintaro\| Hashimoto, Motomu\| Hidaka, Toshihiko\| Abe, Asami\| Ishikawa, Hajime\| Ito, Hiromu\| Kishimoto, Mitsumasa\| Matsui, Kazuo\| Matsui, Toshihiro\| Matsushita, Isao\| Onishi, Akira\| Morinobu, Akio\| Nishida, Keiichiro\| Asai, Shuji\| Tanaka, Eiichi\| Harigai, Masayoshi\| Kojima, Masayo\|
Keywords	late-onset rheumatoid arthritis ageing society questionnaire
Published Date	2024-12-15
Publication Title	Internal Medicine
Volume	volume63
Issue	issue24
Publisher	Japanese Society of Internal Medicine
Start Page	3299
End Page	3306
ISSN	0918-2918
NCID	AA10827774
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by The Japanese Society of Internal Medicine
File Version	publisher
PubMed ID	38692915
DOI	10.2169/internalmedicine.3288-23
CRID	1390021072388391552
Web of Science KeyUT	001388887300002
Related Url	isVersionOf https://doi.org/10.2169/internalmedicine.3288-23

Oncolytic virus-mediated p53 activation boosts the antitumor immunity of a p53-transduced dendritic cell vaccine

FullText URL	fulltext.pdf suppl.pdf
Author	Yamada, Motohiko\| Tazawa, Hiroshi\| Suemori, Kanto\| Okada, Naohiro\| Kajiwara, Yoshinori\| Shoji, Ryohei\| Nagai, Yasuo\| Inoue, Hiroaki\| Hashimoto, Naoyuki\| Kanaya, Nobuhiko\| Kikuchi, Satoru\| Kuroda, Shinji\| Michiue, Hiroyuki\| Urata, Yasuo\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
Published Date	2025-07-19
Publication Title	npj Vaccines
Volume	volume10
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	158
ISSN	2059-0105
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40683859
DOI	10.1038/s41541-025-01219-5
Web of Science KeyUT	001531254800002
Related Url	isVersionOf https://doi.org/10.1038/s41541-025-01219-5

Survival days of patients with metastatic spinal tumors of lung cancer requiring surgery: a prospective multicenter study

FullText URL	fulltext.pdf
Author	Takahashi, Takuya\| Hirai, Takashi\| Shiratani, Yuki\| Suzuki, Akinobu\| Kakutani, Kenichiro\| Kato, Satoshi\| Tominaga, Hiroyuki\| Inoue, Hirokazu\| Sawada, Hirokatsu\| Takegami, Norihiko\| Nakanishi, Kazuo\| Nakajima, Hideaki\| Ishihara, Masayuki\| Oshigiri, Tsutomu\| Funayama, Toru\| Iimura, Takuya\| Tanishima, Shinji\| Nakashima, Hiroaki\| Yamabe, Daisuke\| Hashimoto, Ko\| Uotani, Koji\| Funaba, Masahiro\| Nagoshi, Narihito\| Kobayakawa, Kazu\| Yoshii, Toshitaka\| Watanabe, Kazuyuki\| Nakamae, Toshio\| Kaito, Takashi\| Inoue, Gen\| Imagama, Shiro\| Watanabe, Kota\| Furuya, Takeo\|
Keywords	Metastatic spinal tumor Lung cancer Postoperative survival period Barthel index Vitality index Molecularly targeted therapy
Published Date	2025-07-06
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	24117
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40619496
DOI	10.1038/s41598-025-08775-9
Web of Science KeyUT	001523298400044
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-08775-9

Effects of Palliative Surgical Treatment for Spinal Metastases on the Patient’s Quality of Life With a Focus on the Segment of the Metastasis: A Prospective Multicenter Study

FullText URL	fulltext.pdf
Author	Segi, Naoki\| Nakashima, Hiroaki\| Ito, Sadayuki\| Ouchida, Jun\| Shiratani, Yuki\| Shimizu, Takaki\| Suzuki, Akinobu\| Terai, Hidetomi\| Kakutani, Kenichiro\| Kanda, Yutaro\| Tominaga, Hiroyuki\| Kawamura, Ichiro\| Ishihara, Masayuki\| Paku, Masaaki\| Takahashi, Yohei\| Funaba, Masahiro\| Funayama, Toru\| Nakajima, Hideaki\| Akeda, Koji\| Hirai, Takashi\| Inoue, Hirokazu\| Nakanishi, Kazuo\| Funao, Haruki\| Oshigiri, Tsutomu\| Otsuki, Bungo\| Kobayakawa, Kazu\| Tanishima, Shinji\| Hashimoto, Ko\| Iimura, Takuya\| Sawada, Hirokatsu\| Uotani, Koji\| Manabe, Hiroaki\| Iwai, Chizuo\| Yamabe, Daisuke\| Hiyama, Akihiko\| Seki, Shoji\| Goto, Yuta\| Miyazaki, Masashi\| Watanabe, Kazuyuki\| Nakamae, Toshio\| Kaito, Takashi\| Nagoshi, Narihito\| Kato, Satoshi\| Watanabe, Kota\| Imagama, Shiro\| Inoue, Gen\| Furuya, Takeo\|
Keywords	spinal metastasis metastasis segment palliative surgery quality of life activities of daily living pain anxiety
Published Date	2024-11
Publication Title	Global Spine Journal
Volume	volume15
Issue	issue4
Publisher	SAGE Publications
Start Page	2286
End Page	2299
ISSN	2192-5682
NCID	AA12633225
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024
File Version	publisher
PubMed ID	39484810
DOI	10.1177/21925682241297948
Web of Science KeyUT	001346141500001
Related Url	isVersionOf https://doi.org/10.1177/21925682241297948

Maternal circadian rhythms during pregnancy dictate metabolic plasticity in offspring

FullText URL	fulltext.pdf suppl1.pdf suppl2.xlsx suppl3.xlsx suppl4.xlsx suppl5.xlsx suppl6.xlsx suppl7-1.xlsx suppl7-2.pdf suppl8.pdf
Author	Yao, Na\| Kinouchi, Kenichiro\| Katoh, Manami\| Ashtiani, Kousha Changizi\| Abdelkarim, Sherif\| Morimoto, Hiroyuki\| Torimitsu, Takuto\| Kozuma, Takahide\| Iwahara, Akihide\| Kosugi, Shotaro\| Komuro, Jin\| Kato, Kyosuke\| Tonomura, Shun\| Nakamura, Toshifumi\| Itoh, Arata\| Yamaguchi, Shintaro\| Yoshino, Jun\| Irie, Junichiro\| Hashimoto, Hisayuki\| Yuasa, Shinsuke\| Satoh, Akiko\| Mikami, Yohei\| Uchida, Shusaku\| Ueki, Takatoshi\| Nomura, Seitaro\| Baldi, Pierre\| Hayashi, Kaori\| Itoh, Hiroshi\|
Keywords	circadian rhythm metabolism circadian clock pregnancy developmental origins of health and disease obesity leptin time-restricted feeding caloric restriction eating behavior
Published Date	2025-02
Publication Title	Cell Metabolism
Volume	volume37
Issue	issue2
Publisher	Elsevier BV
Start Page	395
End Page	412.e6
ISSN	1550-4131
NCID	AA11978571
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
PubMed ID	39814018
DOI	10.1016/j.cmet.2024.12.002
Web of Science KeyUT	001427175300001
Related Url	isVersionOf https://doi.org/10.1016/j.cmet.2024.12.002

Eosinophils as a predictive marker of treatment-related adverse events in mRCC patients treated with first-line immune-checkpoint inhibitor combination therapy

FullText URL	fulltext.pdf
Author	Kawada, Tatsushi\| Katayama, Satoshi\| Yanagisawa, Takafumi\| Mori, Keiichiro\| Fukuokaya, Wataru\| Komura, Kazumasa\| Tsujino, Takuya\| Maenosono, Ryoichi\| Takahara, Kiyoshi\| Nukaya, Takuhisa\| Inoki, Lan\| Toyoda, Shingo\| Hashimoto, Takeshi\| Hirasawa, Yosuke\| Edamura, Kohei\| Kobayashi, Tomoko\| Bekku, Kensuke\| Nishimura, Shingo\| Iwata, Takehiro\| Sadahira, Takuya\| Tominaga, Yusuke\| Yamanoi, Tomoaki\| Yoshinaga, Kasumi\| Tsuboi, Kazuma\| Kobayashi, Yasuyuki\| Takamoto, Atsushi\| Kurose, Kyohei\| Kimura, Takahiro\| Azuma, Haruhito\| Shiroki, Ryoichi\| Fujita, Kazutoshi\| Ohno, Yoshio\| Araki, Motoo\|
Keywords	Renal cell carcinoma Immune checkpoint inhibitor ICI Eosinophil Immune-related adverse event Treatment-related adverse event
Published Date	2025-07-25
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	27163
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40715213
DOI	10.1038/s41598-025-08767-9
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-08767-9

Development of a unique tissue-engineered in vitro vascular model with endothelial layer-inverted vascular tissue structure using a cell self-aggregation technique

FullText URL	K0007234_abstract_review.pdf K0007234_summary.pdf K0007234_fulltext.pdf
Author	HASHIMOTO, Shingo\|
Published Date	2025-03-25
Content Type	Thesis or Dissertation
Grant Number	甲第7234号
Granted Date	2025-03-25
Thesis Type	Doctor of Philosophy in Medical Science
Grantor	岡山大学
language	English
Copyright Holders	© 2024 The Society for Biotechnology, Japan.

Promising Effectiveness of Combined Chemotherapy and Immunotherapy in Patients with Advanced Non-small Cell Lung Cancer: A Real-World Prospective Observational Study (CS-Lung-003)

JaLCDOI	10.18926/AMO/68724
FullText URL	79_3_167.pdf
Author	Kanaji, Nobuhiro\| Nishii, Kazuya\| Tsubata, Yukari\| Nakao, Mika\| Okuno, Takae\| Okawa, Sachi\| Takata, Kenji\| Kodani, Masahiro\| Yamasaki, Masahiro\| Fujitaka, Kazunori\| Kubota, Tetsuya\| Inoue, Masaaki\| Watanabe, Naoki\| Hotta, Katsuyuki\| CS-Lung-003 Investigator\|
Abstract	This prospective observational study investigated the clinical status of patients with advanced non-small cell lung cancer (NSCLC) treated with cytotoxic chemotherapy+an immune checkpoint inhibitor (chemo + IO) as first-line treatment in a real-world setting. The cases of 98 patients treated with chemo + IO were prospectively collected and analyzed for effectiveness and safety. The response rate to chemo + IO was 46.9%, and the disease control rate was 76.5%. The median progression-free survival and overall survival (OS) in the total population were 5.2 and 22.3 months, respectively. The patients positive for PD-L1 (≥ 1%) showed significantly longer OS than the negative group (<1%) (median 26.7 vs. 18.7 months, p=0.04). Pre-existing interstitial lung disease (ILD) was associated with shorter OS than the absence of ILD (median 9.0 vs. 22.6 months, p<0.01). Immunerelated adverse events (irAEs) were observed in 28 patients (28.6%). The most frequent irAE was ILD (n=11); Grade 1 (n=1 patient), G2 (n=5), G3 (n=4), and only a single patient with a G5 irAE. In this CS-Lung-003 study, first-line chemo + IO in a real-world setting showed good effectiveness, comparable to that observed in international clinical trials. In real-world practice, chemo + IO is a promising and steadfast strategy.
Keywords	non-small cell lung cancer real-world first-line immune checkpoint inhibitor combined immunotherapy
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2025-06
Volume	volume79
Issue	issue3
Publisher	Okayama University Medical School
Start Page	167
End Page	176
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2025 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	40574255
Web of Science KeyUT	001524768800003

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