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FullText URL fulltext20210428_1.pdf
Author Hagiwara, Yuuki| Yoshida, Kenta| Yoneda, Akira| Torimoto, Junji| Yamamoto, Junji|
Keywords Finite element method Inclusions Laser heating Raman spectroscopy
Published Date 2021-01-05
Publication Title Chemical Geology
Volume volume559
Publisher Elsevier
Start Page 119928
ISSN 00092541
NCID AA0060201X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
DOI 10.1016/j.chemgeo.2020.119928
NAID 120007029907
Web of Science KeyUT 000600546500016
Related Url isVersionOf https://doi.org/10.1016/j.chemgeo.2020.119928
FullText URL fulltext.pdf
Author Sato, Hiroki| Nakamura, Takao| Kusuhara, Toshimasa| Kenichi, Kobara| Kuniyasu, Katsushi| Kawashima, Takaki| Hanayama, Kozo|
Keywords Phase angle Bioelectrical impedance analysis Cole–Cole model Muscle quality
Published Date 2020-10-31
Publication Title Journal of Physiological Sciences
Volume volume70
Issue issue1
Publisher Springer
Start Page 53
ISSN 1880-6546
NCID AA12129145
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Authors
File Version publisher
PubMed ID 33129254
DOI 10.1186/s12576-020-00780-z
Web of Science KeyUT 000587996200002
Related Url isVersionOf https://doi.org/10.1186/s12576-020-00780-z
FullText URL fulltext.pdf
Author Takahashi, Kosuke| Kimura, Shuhei| Hosokawa, Mio Morizane| Shiode, Yusuke| Doi, Shinichiro| Matoba, Ryo| Kanzaki, Yuki| Yonekawa, Yoshihiro| Morizane, Yuki|
Keywords Case report Perfluorocarbon Retinal detachment Subretinal injection Vitreoretinal surgery
Published Date 2020-10-23
Publication Title BMC Ophthalmology
Volume volume20
Issue issue1
Publisher BMC
Start Page 427
ISSN 1471-2415
NCID AA12035369
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s). 2020
File Version publisher
PubMed ID 33097007
DOI 10.1186/s12886-020-01698-1
Web of Science KeyUT 000586445100002
Related Url isVersionOf https://doi.org/10.1186/s12886-020-01698-1
JaLCDOI 10.18926/AMO/60798
FullText URL 74_5_391.pdf
Author Homma, Daisuke| Minato, Izumi| Imai, Norio| Miyasaka, Dai| Sakaif, Yoshinori| Horigome, Yoji| Suzuki, Hayato| Shimada, Hayato| Dohmae, Yoichiro| Endo, Naoto|
Abstract Indexes for objectively evaluating abnormal gait in hip osteoarthritis (OA) patients and determining effective interventions are unclear. We analyzed the abnormal gait of hip OA patients by focusing on movements of the trunk and pelvis to establish an effective evaluation index for each direction of motion. We studied 28 patients with secondary hip OA due to developmental dysplasia of the hip and 16 controls. The trunk and pelvic movements during gait were measured in the medial-lateral (x), vertical (y), and back-and-forth (z) directions by a triaxial angular accelerometer. Gait speed, steps, step length, muscle strength, range of motion, and timed up-and-go (TUG) test performance were measured. We determined the correlations between physical function and the index of abnormal gait in the hip OA patients. Movements other than trunk and pelvic motions in the y-direction indicated abnormal gait in the patients. Significant correlations were found between abnormal gait and range of motions (extension, internal rotation), TUG score, stride length, and steps. The TUG test, stride length and steps were important for evaluating abnormal gait in hip OA patients. Individual interventions for each movement direction are required.
Keywords hip osteoarthritis three-dimensional gait analysis abnormal gait timed up and go test range of motion
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-10
Volume volume74
Issue issue5
Publisher Okayama University Medical School
Start Page 391
End Page 399
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33106694
Web of Science KeyUT 000581970100003
NAID 120006892924
FullText URL fulltext.pdf Table&Figs.pdf
Author Miyazaki, Ikuko| Kikuoka, Ryo| Isooka, Nami| Takeshima, Mika| Sonobe, Kanau| Arai, Rei| Funakoshi, Hidemaru| Quin, Kyle E.| Smart, Smart| Zensho, Kazumasa| Asanuma, Masato|
Keywords Bisphenol A diglycidyl ether Epoxy resin Brain development Neuronal differentiation Anxiety behavior
Note This fulltext is available in March 2021.|
Published Date 2020-03-03
Publication Title Food and Chemical Toxicology
Volume volume138
Publisher Pergamon
Start Page 111235
ISSN 0278-6915
NCID AA10627174
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Elsevier Ltd.
File Version author
PubMed ID 32142877
DOI 10.1016/j.fct.2020.111235
Web of Science KeyUT 000542938400012
Related Url isVersionOf https://doi.org/10.1016/j.fct.2020.111235
JaLCDOI 10.18926/AMO/58269
FullText URL 74_2_115.pdf
Author Kotani, Sayoko| Kamada, Yasuhiko| Shimizu, Keiko| Sakamoto, Ai| Nakatsuka, Mikiya| Hiramatsu, Yuji| Masuyama, Hisashi|
Abstract Thrombosis in decidual vessels is one of the mechanisms of pregnancy loss. However, few studies have assessed the relation between platelet activation, which is known to cause of thrombosis, and recurrent pregnancy loss (RPL). We investigated platelet activation in women with RPL compared to controls by measuring plasma levels of platelet factor 4 (PF4) and β-thromboglobulin (βTG), and assessed correlations between PF4/βTG and coagulative risk factors associated with RPL. The study group included 135 women who had experienced two or more consecutive pregnancy losses. The control group included 28 age-matched healthy women who had never experienced pregnancy loss. PF4 and βTG plasma levels were significantly higher in the women with RPL than controls (PF4: 14.0 [8.0-20.0] vs. 9.0 [6.0-12.0] ng/ml, p=0.043; βTG: 42.0 [24.3-59.8] vs. 31.5 [26.6-36.4] ng/ml, p=0.002). There was a significant association between βTG and anti-phosphatidylethanolamine antibody immunoglobulin M (aPE IgM) (p=0.048). Among the women with RPL, 18 of those who were positive for PF4 (45%) and 18 of those who were positive for βTG (37%) were negative for all known coagulative risk factors associated with RPL. Measurements of PF4 and βTG may be important because they help identify women who are at risk of RPL.
Keywords recurrent pregnancy loss platelet factor 4 β-thromboglobulin platelet activation
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2020-04
Volume volume74
Issue issue2
Publisher Okayama University Medical School
Start Page 115
End Page 122
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 32341585
Web of Science KeyUT 000528278500004
NAID 120006839448
FullText URL fulltext.pdf
Author Takeda, Tatsuaki| Yamamoto, Hiromasa| Suzawa, Ken| Tomida, Shuta| Miyauchi, Shunsaku| Araki, Kota| Nakata, Kentaro| Miura, Akihiro| Namba, Kei| Shien, Kazuhiko| Soh, Junichi| Shien, Tadahiko| Kitamura, Yoshihisa| Sendo, Toshiaki| Toyooka, Shinichi|
Keywords breast cancer drug resistance lung cancer neratinib YES1
Published Date 2019-12-19
Publication Title Cancer Science
Volume volume111
Issue issue3
Publisher Wiley
Start Page 849
End Page 856
ISSN 1347-9032
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 The Authors.
File Version publisher
PubMed ID 31856375
DOI 10.1111/cas.14289
Web of Science KeyUT 000507433400001
Related Url isVersionOf https://doi.org/10.1111/cas.14289
FullText URL fulltext.pdf
Author Karunathilaka, Nuwan| Tada, Naoya| Uemori, Takeshi| Hanamitsu, Ryota| Fujii, Masahiro| Omiya, Yuya| Kawano, Masahiro|
Keywords cold forging high-speed tool steel lubrication residual stress surface roughness tool deformation
Published Date 2019-07-12
Publication Title Metals
Volume volume9
Issue issue7
Publisher MDPI
Start Page 783
ISSN 2075-4701
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 by the authors.
File Version publisher
DOI 10.3390/met9070783
Web of Science KeyUT 000482332400067
Related Url isVersionOf https://doi.org/10.3390/met9070783
FullText URL IJMS20_5_1042.pdf
Author Apriliana Cahya Khayrani| Mahmud, Hafizah| Zahra, Maram H.| Aung Ko Ko Oo| Oze, Miharu| Du, Juan| Alam, Md Jahangir| Afify, Said M.| Hagar A. Abu Quora| Shigehiro, Tsukasa| Anna Sanchez Calle| Okada, Nobuhiro| Seno, Akimasa| Fujita, Koki| Hamada, Hiroki| Seno, Yuhki| Mandai, Tadakatsu| Seno, Masaharu|
Keywords CD44 glycosylated paclitaxel liposome modified paclitaxel ovarian cancer specific targeting
Published Date 2019-02-27
Publication Title International Journal of Molecular Sciences
Volume volume20
Issue issue5
Publisher MDPI
Start Page 1042
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 by the authors.
File Version publisher
PubMed ID 30818864
DOI 10.3390/ijms20051042
Web of Science KeyUT 000462542300041
Related Url isVersionOf https://doi.org/10.3390/ijms20051042
FullText URL eNeurologicalSci_16_100204.pdf
Author Takamiya, Motonori| Takahashi, Yoshiaki| Morimoto, Mizuki| Morimoto, Nobutoshi| Yamashita, Satoshi| Abe, Koji|
Keywords Anti-skeletal muscle protein 5′-nucleotidase 1A antibody Chronic hepatitis C Dysphagia Inclusion body myositis Intravenous immunoglobulin therapy
Note Case Report|
Published Date 2019-09-30
Publication Title eNeurologicalSci
Volume volume16
Publisher Elsevier B.V.
Start Page 100204
ISSN 24056502
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 The Authors. Published by Elsevier B.V.
File Version publisher
PubMed ID 31517073
DOI 10.1016/j.ensci.2019.100204
Related Url isVersionOf https://doi.org/10.1016/j.ensci.2019.100204
FullText URL J_Thorac_Oncol_201907017.pdf
Author Makimoto, Go| Ohashi, Kadoaki| Tomida, Shuta| Nishii, Kazuya| Matsubara, Takehiro| Kayatani, Hiroe| Higo, Hisao| Ninomiya, Kiichiro| Sato, Akiko| Watanabe, Hiromi| Kano, Hirohisa| Ninomiya, Takashi| Kubo, Toshio| Rai, Kammei| Ichihara, Eiki| Hotta, Katsuyuki| Tabata, Masahiro| Toyooka, Shinichi| Takata, Minoru| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords ALK G1202R Alectinib Amphiregulin MET NSCLC
Published Date 2019-07-30
Publication Title Journal of Thoracic Oncology
Volume volume14
Issue issue11
Publisher Elsevier
Start Page 2009
End Page 2018
ISSN 15560864
NCID AA12058455
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.
File Version author
PubMed ID 31374369
DOI 10.1016/j.jtho.2019.07.017
Web of Science KeyUT 000492678300025
Related Url isVersionOf https://doi.org/10.1016/j.jtho.2019.07.017
JaLCDOI 10.18926/AMO/56930
FullText URL 73_4_285.pdf
Author Otani, Yoshihiro| Ichikawa, Tomotsugu| Kurozumi, Kazuhiko| Date, Isao|
Abstract Gliomas are characterized as highly diffuse infiltrating tumors, and currently available treatments such as surgery, radiation and chemotherapy are unfeasible or show limited efficacy against these tumors. Recent genetic and epigenetic analyses of glioma have revealed increasing evidence of the role of driver genetic alterations in glioma development and led to the identification of prognostic factors. Despite these findings, the survival rates of glioma patients remain low, and alternative treatments and novel targets are needed. Recent studies identified neural stem cells as the possible origin of gliomas, and some evidence has revealed shared functions and mechanisms between glioma cells and neurons, also supporting their similarity. The cytoskeleton plays important roles in the migration of normal cells as well as cancer cells. Recent reports have described a role for microtubules, a component of the cytoskeleton, in glioma invasion. Notably, several factors that regulate microtubule functions, such as microtubule-associated proteins, plus-end tracking proteins, or motor proteins, are upregulated in glioma tissues compared with normal tissue, and upregulation of these factors is associated with high invasiveness of glioma cells. In this review, we describe the mechanism of microtubules in glioma invasion and discuss the possibility of microtubule-targeted therapy to inhibit glioma invasion.
Keywords glioma cytoskeletons invasion microtubules
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2019-08
Volume volume73
Issue issue4
Publisher Okayama University Medical School
Start Page 285
End Page 297
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31439951
JaLCDOI 10.18926/AMO/56647
FullText URL 73_2_117.pdf
Author Yamasaki, Yukie| Tamiya, Nanako| Yamamoto, Hideki| Miyaishi, Satoru|
Abstract According to the World Health Organization’s World Report, approx. 950,000 children and young people < 18 years old die from an injury each year, and unintentional injury deaths account for a large portion of these cases. Here we used medico-legal documents to epidemiologically analyze the cases of unintentional injury deaths among children < 5 years old in Okayama Prefecture, Japan from 2001 to 2015. Age, sex, manner/cause of death, and various circumstances of the incident were investigated. There were 73 unintentional injury deaths during the study period. Drowning (n=29), suffocation (n=24), and transport accidents (n=13) were the major categories of unintentional injury deaths. Twenty-two cases (30.1%) were autopsied. Differences in the characteristics of the unintentional injury deaths by age were observed. Information which cannot be obtained from Vital Statistics was available from medico-legal documents, and detailed characteristics of unintentional injury deaths among children < 5 years old were elucidated. Investigating medico-legal information is one of the meaningful measures for the prevention of unintentional injury deaths among children in Japan.
Keywords child death unintentional injury prevention medico-legal document
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-04
Volume volume73
Issue issue2
Publisher Okayama University Medical School
Start Page 117
End Page 125
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31015746
FullText URL K0005463_other1.pdf
Author Higuchi, Yuji | Uchitomi, Yosuke| Fujimori, Maiko| Koyama, Toshihiro| Kataoka, Hitomi| Kitamura, Yoshihisa| Sendo, Toshiaki| Inagaki, Masatoshi|
Keywords Empathy Hospital pharmacist Japan Pharmaceutical care
Note The final publication is available at Springer| 岡山大学審査学位副論文|
Published Date 2015-12
Publication Title International Journal of Clinical Pharmacy
Volume volume37
Issue issue6
Publisher Springer
Start Page 1258
End Page 1266
ISSN 2210-7703
NCID AA12633112
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version author
PubMed ID 26441314
DOI 10.1007/s11096-015-0204-2
Web of Science KeyUT 000363490100042
Related Url https://doi.org/10.1007/s11096-015-0204-2 http://ousar.lib.okayama-u.ac.jp/55016
Title Alternative A case report of giant ectopic pheochromocytoma conversion therapy with radioisotope therapy and chemotherapy followed by curative resection
FullText URL 127_213.pdf
Author Yasui, Kazuya| Umeda, Yuzo| Kumano, Kenjiro| Tabata, Masahiro| Otsuka, Fumio| Yagi, Takahito| Fujiwara, Toshiyoshi|
Abstract A 46-year-old man was found to be positive for occult blood at a medical checkup and was revealed to have a 14-cm tumor on the right side of abdominal aorta by a subsequent abdominal CT scan. The endocrinology laboratory data showed elevations in the levels of serum noradrenaline, and ectopic pheochromocytoma was suspected. The tumor was compressing the inferior vena cava and portal vein, the superior mesenteric artery and the pancreas. Since it would be difficult to cure by operation, neoadjuvant therapy was started using radioisotope therapy by I-131 metaiodobenzylguanidine (131I-MIBG) and chemotherapy (CVD therapy ; cyclophosphamide, vincristine, dacarbazine). He was treated with three courses of radioisotope therapy and 16 courses of chemotherapy, which significantly reduced the tumor size. This made radical resection possible ; we were able to avoid the merger excision of great vessels and other organs. On pathological and immunopathological findings, the tumor was diagnosed as ectopic pheochromocytoma. Regarding the safety and curability of the treatment, neoadjuvant therapy may be useful in treating very large tumors that show invasion of other organs.
Keywords 異所性褐色細胞腫(ectopic pheochromocytoma) 化学療法(chemo therapy) 131I-MIBG
Publication Title 岡山医学会雑誌
Published Date 2015-12-01
Volume volume127
Issue issue3
Start Page 213
End Page 218
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.127.213
language Japanese
Copyright Holders Copyright (c) 2015 岡山医学会
File Version publisher
DOI 10.4044/joma.127.213
NAID 130005116814
JaLCDOI 10.18926/AMO/53122
FullText URL 69_1_51.pdf
Author Mu Mu Shwe| Kyi Kyi Nyunt| Okada, Shigeru| Harano, Teruo| Hlaing Myat Thu| Hla Myat Mo Mo| Mo Mo Win| Khin Khin Oo| KhinThet Wai| Khin Saw Aye| Myo Khin|
Abstract Persistent infection with oncogenic types of human papillomavirus (HPV) is the most important risk factor associated with cervical cancer. This study detected the oncogenic HPV genotypes in cervical neoplasia in relation to clinicopathological findings using a cross-sectional descriptive method in 2011 and 2012. Cervical swabs and colposcopy-directed cervical biopsy tissues were collected from 108 women (median age 45 years;range 20-78) showing cervical cytological changes at Sanpya General Hospital, Yangon, Myanmar. HPV DNA testing and genotyping were performed by polymerase chain reaction and restriction fragment length polymorphism. HPV was identified in women with cervical intraepithelial neoplasia (CIN) 1 (44.4%), CIN2 (63.2%), CIN3 (70.6%), and squamous cell carcinoma (SCC) (74.1%). The association between cervical neoplasia and HPV positivity was highly significant (p=0.008). Most patients infected with HPV were between 40-49 years of age, and the youngest were in the 20- to 29-year-old age group. The most common genotype was HPV 16 (65.6%) with the following distribution:70% in CIN1, 41.7% in CIN2, 91.7% in CIN3, and 60% in SCC. HPV-31 was the second-most frequent (21.9%):30% in CIN1, 33.3% in CIN2, 8.3% in CIN3, and 15% in SCC. The third-most frequent-genotype was HPV-18 (7.8%):8.3% in CIN1, and 20% in SCC. Another genotype was HPV-58 (4.7%):16.7% in CIN1 and 5% in SCC. The majority of CIN/SCC cases were associated with HPV genotypes 16, 31, 18, and 58. If oncogenic HPV genotypes are positive, the possibility of cervical neoplasia can be predicted. Knowledge of the HPV genotypes distribution can predict the effectiveness of the currently used HPV vaccine.
Keywords human papillomavirus genotyping Myanmar
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2015-02
Volume volume69
Issue issue1
Publisher Okayama University Medical School
Start Page 51
End Page 58
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2015 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 25703171
Web of Science KeyUT 000349740300006
Author Abe, N| Hou, D-X| Munemasa, S| Murata, Y| Nakamura, Y|
Published Date 2014-11-20
Publication Title Cell Death and Disease
Volume volume5
Content Type Journal Article
Author Nakabayashi, Hidekazu| Taketa, Kazuhisa|
Published Date 2012-12-03
Publication Title 岡山医学会雑誌
Volume volume124
Issue issue3
Content Type Journal Article
Author Wakimoto, Shuichi| Suzumori, Koichi| Ogura, Keiko|
Published Date 2011
Publication Title Advanced Robotics
Volume volume25
Issue issue9-10
Content Type Journal Article
Author Ishimitsu, Tetsusaburo|
Published Date 1959-10-30
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue11-2
Content Type Journal Article