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ID 31131
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Author
Hashimura, Shinji
Kohno, Yoshihiro
Gohbara, Hideo
Niiya, Harutaka
Hiraki, Yoshio
Abstract

99mTc-DTPA-galactosyl human serum albumin (Tc-GSA) is a new liver-imaging agent which binds specifically to hepatic binding protein. The purpose of this study was to evaluate the usefulness of Tc-GSA in quantitatively evaluating hepatic ischemia-reperfusion injury in the rat. Regional hepatic ischemia was induced by clamping the left hepatic artery and the left portal vein for 5 to 45 min. A hepatic accumulation index (t90) was obtained on the basis of the dynamic data. A significant difference of this index was observed between all ischemic groups and the control. In conclusion, 99mTc-GSA appears useful for evaluating the hepatic ischemia-reperfusion injury.</P>

Keywords
99mTc-DTPA-galactosyl human serum albumin
liver scintigraphy
hepatic ischemia-reperfusion injury
Amo Type
Article
Publication Title
Acta Medica Okayama
Published Date
1994-02
Volume
volume48
Issue
issue1
Publisher
Okayama University Medical School
Start Page
39
End Page
42
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT