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FullText URL olj_71_1_contents.pdf
Author 岡山大学法学会|
Publication Title Okayama Law Journal
Published Date 2021-08-31
Volume volume71
Issue issue1
ISSN 0386-3050
language Japanese
File Version publisher
FullText URL fulltext20210915.pdf
Author Hyodo, Kiwamu|
Note This is a post-peer-review, pre-copyedit version of an article published in Journal of General Plant Pathology. The final authenticated version is available online at: https://doi.org/10.1007/s10327-021-01022-9 This fulltext is available in Sep. 2022.|
Published Date 2021-8-31
Publication Title Journal of General Plant Pathology
Volume volume87
Issue issue6
Publisher Springer Science and Business Media LLC
Start Page 415
End Page 417
ISSN 1345-2630
NCID AA11449093
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Springer Nature Switzerland AG.
File Version author
DOI 10.1007/s10327-021-01022-9
Related Url isVersionOf https://doi.org/10.1007/s10327-021-01022-9
FullText URL fulltext20210914-1.pdf figures20210914-1.pdf
Author Higuchi, Hitoshi| Takaya-Ishida, Kumiko| Miyake, Saki| Fujimoto, Maki| Nishioka, Yukiko| Maeda, Shigeru| Miyawaki, Takuya|
Note This is an Accepted Manuscript of an article published by Elsevier.
© 2021 The American Association of Oral and Maxillofacial Surgeon. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.joms.2021.04.004] .|
Published Date 2021-9
Publication Title Journal of Oral and Maxillofacial Surgery
Volume volume79
Issue issue9
Publisher Elsevier BV
Start Page 1842
End Page 1850
ISSN 0278-2391
NCID AA10628202
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The American Association of Oral and Maxillofacial Surgeon
File Version author
PubMed ID 34022138
DOI 10.1016/j.joms.2021.04.004
Web of Science KeyUT 000691194500011
Related Url https://doi.org/10.1016/j.joms.2021.04.004
FullText URL fulltext.pdf
Author Kondo, Hideki| Yoshida, Naoto| Fujita, Miki| Maruyama, Kazuyuki| Hyodo, Kiwamu| Hisano, Hiroshi| Tamada, Tetsuo| Andika, Ida Bagus| Suzuki, Nobuhiro|
Keywords Betaflexiviridae quinvirus bymovirus yellow mosaic disease wheat virome soil borne variants
Published Date 2021-08-19
Publication Title Frontiers In Microbiology
Volume volume12
Publisher Frontiers Media SA
Start Page 715545
ISSN 1664-302X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Kondo, Yoshida, Fujita, Maruyama, Hyodo, Hisano, Tamada, Andika and Suzuki.
File Version publisher
PubMed ID 34489904
DOI 10.3389/fmicb.2021.715545
Web of Science KeyUT 000692554100001
Related Url isVersionOf https://doi.org/10.3389/fmicb.2021.715545
FullText URL fulltext.pdf
Author Kikuchi, Masuzu| Kojima, Keiichi| Nakao, Shin| Yoshizawa, Susumu| Kawanishi, Shiho| Shibukawa, Atsushi| Kikukawa, Takashi| Sudo, Yuki|
Published Date 2021-07-20
Publication Title Scientific Reports
Volume volume11
Issue issue1
Publisher Nature Portfolio
Start Page 14765
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021
File Version publisher
PubMed ID 34285294
DOI 10.1038/s41598-021-94181-w
Web of Science KeyUT 000692201200025
Related Url isVersionOf https://doi.org/10.1038/s41598-021-94181-w
FullText URL fulltext.pdf
Author Matsumoto, Kazuyuki| Kato, Hironari| Kitano, Masayuki| Hara, Kazuo| Kuwatani, Masaki| Ashida, Reiko| Takenaka, Mamoru| Yamazaki, Tatsuhiro| Sakurai, Jun| Yoshida, Michihiro| Okada, Hiroyuki|
Keywords gastroenterology endoscopy pancreatic disease
Published Date 2021
Publication Title BMJ Open
Volume volume11
Issue issue7
Publisher BMJ Publishing Group
Start Page e046505
ISSN 2044-6055
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Author(s) (or their employer(s)) 2021.
File Version publisher
PubMed ID 34253667
DOI 10.1136/bmjopen-2020-046505
Web of Science KeyUT 000691612700018
Related Url isVersionOf https://doi.org/10.1136/bmjopen-2020-046505
FullText URL fulltext.pdf
Author Ahmed, Feroz| Yoshida, Yuichi| Wang, Jin| Sakai, Kenji| Kiwa, Toshihiko|
Published Date 2021-07-26
Publication Title AIP Advances
Volume volume11
Issue issue7
Publisher AIP Publishing
Start Page 75224
ISSN 2158-3226
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Author(s).
File Version publisher
DOI 10.1063/5.0056597
Web of Science KeyUT 000692318200001
Related Url isVersionOf https://doi.org/10.1063/5.0056597
JaLCDOI 10.18926/AMO/62410
FullText URL 75_4_543.pdf
Author Yoshida, Ryuichi| Yagi, Takahito| Yasui, Kazuya| Umeda, Yuzo| Yoshida, Kazuhiro| Fuji, Tomokazu| Takagi, Kosei| Kumano, Kenjiro| Yoshimoto, Masashi| Fujiwara, Toshiyoshi|
Abstract The outcomes of pancreatectomy with resection and reconstruction of the involved arteries for locally advanced pancreatic cancer following chemotherapy have improved in recent years. In pancreatic head cancers in which there is contact with the common and proper hepatic arteries, margin-negative resection requires pancreati-coduodenectomy, with the resection of these arteries and the restoration of hepatic arterial flow. Here, we describe a middle colic artery transposition technique in hepatic arterial reconstruction during pancreatoduo-denectomy for an initially unresectable locally advanced pancreatic cancer. This technique was effective and may provide a new option for hepatic artery reconstruction in such cases.
Keywords hepatic artery locally advanced pancreatic cancer middle colic artery pancreatoduodenectomy reconstruction technique
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 543
End Page 548
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511625
Web of Science KeyUT 000696755800004
NAID 120007146036
JaLCDOI 10.18926/AMO/62409
FullText URL 75_4_539.pdf
Author Yamamoto, Yukichika| Otsuka, Yuki| Katsuyama, Takayuki| Nishimura, Yoshito| Oka, Kosuke| Hasegawa, Kou| Hagiya, Hideharu| Otsuka, Fumio|
Abstract Primary Sjögren’s syndrome (SS) is an autoimmune disease that usually affects the exocrine glands in mid-dle-aged women. Fifteen percent of SS patients experience severe systemic extraglandular complications, and pleuritis is one of the rare complications of SS. We report the case of an elderly Japanese man who initially pre-sented with a prolonged fever and chest pain and was finally diagnosed with primary SS-associated pleuritis. Of the nine reported cases of primary SS that initially presented with pleuritis, up to six cases were elderly males. This case highlights the complication of pleuritis among elderly males with primary SS.
Keywords Sjögren’s syndrome pleuritis elderly male
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 539
End Page 542
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511624
Web of Science KeyUT 000696755800003
NAID 120007146035
JaLCDOI 10.18926/AMO/62408
FullText URL 75_4_533.pdf
Author Tsuchie, Hiroyuki| Miyakoshi, Naohisa| Nagasawa, Hiroyuki| Shimada, Yoichi|
Abstract Tumor lysis syndrome (TLS) is a complication of cancer treatment that requires urgent intervention. It is extremely rare in the treatment of soft tissue sarcoma (STS) of the limbs or trunk, and there are currently no reports of TLS occurrence from eribulin therapy. We report the case of a 78-year-old woman with an undiffer-entiated pleomorphic sarcoma on the right buttock. We initiated chemotherapy with intravenous eribulin mesylate. Deterioration of renal function, mild hyperkalemia, hyperuricemia, hypocalcemia, and hyperphos-phatemia were confirmed on examination, suggesting the presence of TLS. We present an extremely rare case of TLS from eribulin for STS.
Keywords tumor lysis syndrome eribulin soft tissue sarcoma cancer chemotherapy metastasis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 533
End Page 538
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511623
Web of Science KeyUT 000696755800002
NAID 120007146034
JaLCDOI 10.18926/AMO/62407
FullText URL 75_4_529.pdf
Author Inada, Ryo| Watanabe, Ayako| Toshima, Toshiaki| Katsura, Yuki| Sato, Takuji| Sui, Kenta| Oishi, Kazuyuki| Okabayashi, Takehiro| Ozaki, Kazuhide| Shibuya, Yuichi| Matsumoto, Manabu| Iwata, Jun|
Abstract A 67-year-old woman underwent polypectomy for a tumor at the descending colon. Pathologically, the tumor was diagnosed as adenocarcinoma with an invasion of 2000 μm. Computed tomography showed a swollen paracolic lymph node and a mass lesion in the presacral space. Magnetic resonance imaging revealed a multio-cular cystic lesion. On diagnosis of descending colon cancer and tailgut cyst, she underwent synchronous lapa-roscopic resection. Histopathologically, the colon cancer was diagnosed as pT1bN1M0, pStage IIIa. The pre-sacral cystic lesion was diagnosed as a nonmalignant tailgut cyst with negative surgical margin. The patient is currently doing well without recurrence at 28 months.
Keywords anterior approach laparoscopic resection tailgut cyst
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 529
End Page 532
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511622
Web of Science KeyUT 000696755800001
NAID 120007146033
JaLCDOI 10.18926/AMO/62406
FullText URL 75_4_523.pdf
Author Yamashita, Mampei| Kuroki, Tamotsu| Matsuoka, Yuki| Miura, Shiro| Hamada, Takashi| Hirayama, Takanori| Yoneda, Akira| Tokunaga, Takayuki| Yamanouchi, Kosho| Takeshita, Hiroaki| Maeda, Shigeto|
Abstract Acute mesenteric ischemia (AMI) is often caused by superior mesenteric artery (SMA) embolization. We report a rare case of synchronous celiac axis and SMA embolization in an elderly woman with initially mild abdominal pain. Ultimately, a second contrast-enhanced computed tomography revealed extensive necrosis from the stomach to the transverse colon together with liver ischemia due to hours of occlusion. Multiorgan failure made palliation the only option, and she died the following evening. Autopsy revealed a fragile atherosclerosis-asso-ciated thrombus. Careful examination and repeat diagnostic tests should be performed in patients with mild abdominal symptoms at risk for AMI.
Keywords atherosclerosis celiac axis mesenteric ischemia superior mesenteric artery thromboembolism
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 523
End Page 527
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511621
Web of Science KeyUT 000709282300007
NAID 120007146032
JaLCDOI 10.18926/AMO/62405
FullText URL 75_4_517.pdf
Author Ochi, Masahiko| Iida, Atsuyoshi| Takahashi, Yuka| Tanaka, Masamichi| Saito, Hironori| Naito, Hiromichi| Mikane, Takeshi| Fuke, Soichiro|
Abstract Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically mediated cardiomyopathy charac-terized by progressive myocardial loss of the right ventricle and its replacement by fibrofatty tissue, causing dyskinesia, aneurysm, and/or arrhythmia. The prevalence of ARVC is estimated to be 1 in 2,000-5,000, with the condition accounting for up to 20% of sudden cardiac deaths in individuals < 35 years old. This report describes the case of 61-year-old Japanese who was diagnosed with ARVC after cardiac arrest (CA) and successful resusci-tation. After the sudden CA, the restoration of spontaneous circulation was achieved with appropriate resusci-tation, followed by the introduction of target temperature management in the intensive care unit. He was diag-nosed with ARVC based on angiography and histology results. An ICD (implantable cardioverter-defibrillator) was implanted, and he was discharged without neurological sequelae 1 month post-CA. ARVC is an important cause of sudden CA, and successfully resuscitated patients with right ventricular dilation should undergo testing to rule out ARVC.
Keywords inverted T-wave right ventricular dilatation sudden cardiac arrest sudden cardiac death
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 517
End Page 521
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511620
Web of Science KeyUT 000709282300006
NAID 120007146031
JaLCDOI 10.18926/AMO/62404
FullText URL 75_4_511.pdf
Author Kataoka, Yuko| Maeda, Yukihide| Sugaya, Akiko| Omichi, Ryotaro| Kariya, Shin|
Abstract WHO has recommended various measures to combat the COVID-19 pandemic, including mask-wearing and physical distancing. However, these changes impair communication for individuals with hearing loss. We investigated the changes in auditory communication associated with COVID-19 measures in 269 patients (male: 45.7%, female: 54.3%, median age: 54 y.o.). Most patients with hearing loss had difficulty engaging in auditory communication with people wearing masks, especially in noisy surroundings or with physical distanc-ing. These difficulties were noticeable in patients with severe hearing loss. Developing communication support strategies for people with hearing loss is an urgent need while COVID-19 measures are in place.
Keywords coronavirus disease 2019 (COVID-19) hearing loss communication problem mask physical distance
Amo Type Short Communication
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 511
End Page 516
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511619
Web of Science KeyUT 000709282300005
NAID 120007146030
JaLCDOI 10.18926/AMO/62403
FullText URL 75_4_505.pdf
Author Okamura, Tomoka| Washio, Yosuke| Watanabe, Hirokazu| Nakanishi, Hidehiko| Uchiyama, Atsushi| Tsukahara, Hirokazu| Kusuda, Satoshi|
Abstract Late-onset circulatory collapse (LCC) in preterm infants is presumably caused by relative adrenal insufficiency. Because eosinophilia is known to be associated with adrenal insufficiency, we attempted to clarify the relation-ship between eosinophilia and LCC in preterm infants. We divided the cases of the infants (born at < 28 weeks’ gestation) admitted to our neonatal intensive care unit in 2008-2010 into 2 groups: those diagnosed with LCC that received glucocorticoids (LCC group), and those who did not receive glucocorticoids (control group). We compared eosinophil counts between the 2 groups and between before and after glucocorticoid treatment in the LCC group. A total of 28 infants were examined: LCC group (n = 12); control group (n = 16). The peak eosin-ophil counts of the LCC group were significantly higher than those of the control group (median: 1.392 × 109/L vs. 1.033 × 109/L, respectively; p = 0.02). Additionally, in the LCC group, the eosinophil counts declined significantly after glucocorticoid treatment (0.877 × 109/L vs. 0.271 × 109/L, p = 0.003). Eosinophil counts in the LCC group were significantly higher than in the control group and decreased rapidly after gluco-corticoid treatment. These results indicate that eosinophilia may be a factor associated with LCC caused by adrenal insufficiency.
Keywords late-onset circulatory collapse preterm infant eosinophilia steroid adrenal insufficiency
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 505
End Page 509
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511618
Web of Science KeyUT 000709282300004
NAID 120007146046
JaLCDOI 10.18926/AMO/62402
FullText URL 75_4_495.pdf
Author Sugiyama, Shuntaro| Iida, Takatoshi| Morimoto, Yoshinari| Yamazaki, Yuki| Mikuzuki, Lou| Hayashi, Megumi|
Abstract Tablet size and head posture have been reported to affect swallowing of medications, but no previous studies have evaluated their effects in detail. Our aim was to investigate for the first time the effect of tablet size and head posture on drug swallowing by endoscopic evaluation in healthy subjects. Round tablets (7 , 10 , 12, and 14 mm in diameter) were swallowed by 15 healthy adults with an endoscope inserted in the neutral, head flex-ion, and head extension positions. Evaluation of swallowing difficulty using a numeric rating scale (NRS), presence or absence of pharyngeal residue and its location, and tablet oral transit time (TOTT) were recorded. In the neutral position, the NRS score was higher with the 14 mm tablets than with the 7 mm tablets. The TOTT with the 7 mm tablets was significantly shorter in the head extension than in the neutral position. Swallowing difficulty increased when the tablet diameter was more than 7 mm. Residues were found in the epi-glottis, pyriform sinus, and tongue base. These findings suggest that head extension shortens the TOTT and assists oral-pharyngeal transport.
Keywords tablet size head posture swallowing endoscopy pharyngeal residue
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 495
End Page 503
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511617
Web of Science KeyUT 000709282300003
NAID 120007146045
JaLCDOI 10.18926/AMO/62401
FullText URL 75_4_487.pdf
Author Kunna, Ezzan| Yamamoto, Taro| Nundu, Sabin| Akintije, Calliope | Elkhidir, Isam |
Abstract Ebola virus disease (EVD) is a highly contagious and fatal disease in humans. Healthcare providers (HCPs) are often at the frontline of epidemics and can thus be in jeopardy of contracting EVD. Sudan is at a great risk of an EVD outbreak, as it borders countries that experienced EVD outbreaks. It is therefore imperative in Sudan to assess the HCPs’ awareness and knowledge, attitude, and practice (KAP) about EVD for its control and man-agement and for preparedness. A KAP survey was conducted among 387 HCPs (physicians, nurses and labora-tory technicians) in the three main tertiary hospitals in Khartoum, Sudan. The majority of the survey respon-dents (54.5%) were females, < 30 years old (76.3%), and single (77.4%). Most (94%) had heard about EVD, 62% from classical media. Only 14% had received education or training regarding EVD. About 40% reported being adherent to universal precautions and 72% were willing to deal with EVD patients under safety precau-tions. Only 10% knew of any available standard national guidelines for EVD. Nearly half of the HCPs (47%) rated the potential risk of an EVD outbreak in Sudan as high, and 52% rated health authorities’ effort against it as weak. These findings revealed the HCPs’ insufficient knowledge of EVD and the necessary universal precau-tions. This lack of knowledge would negatively affect the HCPs’ preparedness toward any potential EVD out-break. There is a dire need to train HCPs in Sudan on the management of EVD, including preventive and con-trol measures.
Keywords Ebola virus Sudan healthcare provider knowledge attitude and practice
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 487
End Page 493
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511616
Web of Science KeyUT 000709282300002
NAID 120007146044
JaLCDOI 10.18926/AMO/62400
FullText URL 75_4_479.pdf
Author Harada, Akio| Kawai, Nobuyuki| Ogawa, Tomoya| Hatakeyama, Tetsuhiro| Tamiya, Takashi|
Abstract Instances of traumatic brain injury (TBI) in the elderly have been increasing along with the aging of popula-tions. In the present study, we examined the effect of aging on long-term multidisciplinary in-patient rehabili-tation efficacy after TBI. Sixty-three patients with physical and cognitive impairments after TBI were enrolled in this study. Patients were divided into 4 age groups (≤ 24, 25-44, 45-64, ≥ 65 years) and the clinical charac-teristics and rehabilitation efficacy of each age group were determined. Functional disability was evaluated using motor and cognitive Functional Independence Measure (FIM) scores. Rehabilitation efficacy was assessed by FIM gains during rehabilitation and compared among the groups. There were no statistically significant dif-ferences in motor and cognitive FIM gains among the age groups. However, cognitive FIM gain was limited in a subset of ≥ 65 patients, and initial cognitive measures could not predict cognitive FIM improvement. These results indicate that chronological age is insufficient to accurately predict rehabilitation efficacy in older TBI patients, and that such patients should be considered candidates for intensive rehabilitation programs based on these results. Accurate prognostication of rehabilitation efficacy with continuing data collection is important when using rehabilitation resources for older TBI patients.
Keywords aging Functional Independence Measure physical and cognitive impairments traumatic brain injury rehabilitation
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 479
End Page 486
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511615
Web of Science KeyUT 000709282300001
NAID 120007146043
JaLCDOI 10.18926/AMO/62399
FullText URL 75_4_471.pdf
Author Iwamuro, Masaya| Toyokawa, Tatsuya| Matsueda, Kazuhiro| Hori, Shinichiro| Yoshioka, Masao| Moritou, Yuki| Tanaka, Takehiro| Mizuno, Motowo| Okada, Hiroyuki|
Abstract The characteristics of gastric polyps in patients with Peutz-Jeghers (PJ) syndrome (PJS) have not been fully investigated. The objective of this study was to reveal the endoscopic and pathologic findings of gastric polyps in patients with PJS. We reviewed 11 patients with PJS treated at 6 institutions, and summarized the endo-scopic and pathologic features of their gastric polyps. The polyps were mainly classified into 2 types: (i) soli-tary or sporadic polyps > 5 mm, reddish in color with a sessile or semi-pedunculated morphology (n = 9); and (ii) multiple sessile polyps ≤ 5 mm with the same color tone as the peripheral mucosa (n = 9). Patients who underwent endoscopic mucosal resection for polyps > 5 mm were diagnosed with PJ polyps (n = 2), whereas those who underwent biopsy were diagnosed with hyperplastic polyps. Polyps ≤ 5 mm were pathologically diagnosed as fundic gland polyps or hyperplastic polyps. This study revealed that patients with PJS present with 2 types of polyps in the stomach. Endoscopic mucosal resection of polyps > 5 mm seems necessary for the pathologic diagnosis of PJ polyps.
Keywords Peutz-Jeghers syndrome esophagogastroduodenoscopy gastric polyps
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 471
End Page 477
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511614
Web of Science KeyUT 000701717000001
NAID 120007146042
JaLCDOI 10.18926/AMO/62398
FullText URL 75_4_461.pdf
Author Murakami, Hiroyuki| Yoshioka, Takanori| Moriyama, Takashi| Ishikawa, Tatsunori| Makita, Masanori| Sunami, Kazutaka|
Abstract Bendamustine plus rituximab (B-R) is an effective therapy for relapsed or refractory (r/r) low-grade B-cell lymphoma (LGBCL) and mantle cell lymphoma (MCL); however, clinical data from Japanese patients treated with B-R therapy are limited. We retrospectively evaluated the efficacy and safety of B-R therapy in 42 patients who received B-R therapy at our hospital for r/r LGBCL and MCL. All patients received intravenous (IV) ritux-imab 375 mg/m2 on day 1 and IV bendamustine 90 mg/m2 on days 2 and 3 every 28 days for up to 6 cycles. The common histologic subtypes were follicular lymphoma (n = 29, 70%), marginal zone lymphoma (n = 6, 14%), and MCL (n = 5, 12%). The overall response rate was 93%, with 62% complete response and complete response unconfirmed. The median progression-free survival (PFS) was 38 months (95% confidence interval [CI], 24.6 to not reached [NR]), and the median overall survival (OS) was 80 months (95% CI, 60.7 to NR). Patients receiving a cumulative dose of bendamustine ≥ 720 mg/m2 showed a significantly longer PFS and OS. Grade 3/4 adverse events (≥ 10%) included neutropenia (55%), lymphopenia (69%), and nausea (24%). B-R therapy was effective and well tolerated, and the cumulative dose of bendamustine was associated with a favorable outcome.
Keywords bendamustine low grade B-cell lymphoma mantle cell lymphoma
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-08
Volume volume75
Issue issue4
Publisher Okayama University Medical School
Start Page 461
End Page 469
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34511613
Web of Science KeyUT 000697944600008
NAID 120007146041