result 11269 件
| FullText URL | K0005023_abstract_review.pdf K0005023_fulltext.pdf |
|---|---|
| Author | Morito, Yuki| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5023号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | Kobayashi, Koichiro| |
|---|---|
| Published Date | 2014-09-30 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Title Alternative | Molecular target therapies in rheumatic diseases |
|---|---|
| FullText URL | 126_227.pdf |
| Author | Wakabayashi, Hiroshi| |
| Keywords | リウマチ性疾患 自己免疫疾患 生物学的製剤 分子標的薬 |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 227 |
| End Page | 230 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.227 |
| NAID | 130004903237 |
| Title Alternative | Modulation of neuronal function and neuroprotection by astrocytes |
|---|---|
| FullText URL | 126_203.pdf |
| Author | Asanuma, Masato| |
| Keywords | アストロサイト 抗酸化防御機構 パーキンソン病 メタロチオネイン Nrf2 |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 203 |
| End Page | 208 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.203 |
| NAID | 130004903243 |
| Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2013 Sunada Prize) |
|---|---|
| FullText URL | 126_195.pdf |
| Author | Akagi, Satoshi| |
| Abstract | 受賞対象論文: Akagi S, Nakamura K, Matsubara H, Kusano KF, Kataoka N, Oto T, Miyaji K, Miura A, Ogawa A, Yoshida M, Ueda-Ishibashi H, Yutani C, Ito H：Prostaglandin I2 induces apoptosis via upregulation of Fas ligand in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. Int J Cardiol (2013) 165, 499-505. |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 195 |
| End Page | 197 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.195 |
| NAID | 130004903242 |
| Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in Cancer Research (2013 Hayashibara Prize and Yamada Prize) |
|---|---|
| FullText URL | 126_191.pdf |
| Author | Shien, Kazuhiko| |
| Abstract | 受賞対象論文: Shien K, Toyooka S, Yamamoto H, Soh J, Jida M, Thu KL, Hashida S, Maki Y, Ichihara E, Asano H, Tsukuda K, Takigawa N, Kiura K, Gazdar AF, Lam WL, Miyoshi S：Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells. Cancer Res (2013) 73, 3051-3061. |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 191 |
| End Page | 194 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.191 |
| NAID | 130004903236 |
| Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in General Medical Science (2013 Yuuki Prize) |
|---|---|
| FullText URL | 126_187.pdf |
| Author | Yamamoto, Hiromasa| |
| Abstract | 受賞対象論文: Yamamoto H, Higasa K, Sakaguchi M, Shien K, Soh J, Ichimura K, Furukawa M, Hashida S, Tsukuda K, Takigawa N, Matsuo K, Kiura K, Miyoshi S, Matsuda F, Toyooka S：Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas. J Natl Cancer Inst (2014) 106, djt338 |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 187 |
| End Page | 190 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.187 |
| NAID | 130004903235 |
| Author | Oshima, Masamitsu| Inoue, Kaoru| Nakajima, Kei| Tachikawa, Tetsuhiko| Yamazaki, Hiromichi| Isobe, Tomohide| Sugawara, Ayaka| Ogawa, Miho| Tanaka, Chie| Saito, Masahiro| Kasugai, Shohei| Takano-Yamamoto, Teruko| Inoue, Takashi| Tezuka, Katsunari| Kuboki, Takuo| Yamaguchi, Akira| Tsuji, Takashi| |
|---|---|
| Published Date | 2014-08-13 |
| Publication Title | Scientific Reports |
| Volume | volume4 |
| Content Type | Journal Article |
| Author | Mori, Izumi C.| Arias-Barreiro, Carlos R.| Koutsaftis, Apostolos| Ogo, Atsushi| Kawano, Tomonori| Yoshizuka, Kazuharu| Inayat-Hussain, Salmaan H.| Aoyama, Isao| |
|---|---|
| Published Date | 2015-02 |
| Publication Title | Chemosphere |
| Volume | volume120 |
| Content Type | Journal Article |
| Author | Rikiishi, Kazuhide| Maekawa, Masahiko| |
|---|---|
| Published Date | 2014-09-11 |
| Publication Title | PLoS ONE |
| Volume | volume9 |
| Issue | issue9 |
| Content Type | Journal Article |
| Author | Ichiyanagi, Tomoko| Ichiyanagi, Kenji| Ogawa, Ayako| Kuramochi-Miyagawa, Satomi| Nakano, Toru| Chuma, Shinichiro| Sasaki, Hiroyuki| Udono, Heiichiro| |
|---|---|
| Published Date | 2014-09-27 |
| Publication Title | Nucleic Acids Research |
| Volume | volume42 |
| Issue | issue19 |
| Content Type | Journal Article |
| Author | Hiasa, Miki| Miyaji, Takaaki| Haruna, Yuka| Takeuchi, Tomoya| Harada, Yuika| Moriyama, Sawako| Yamamoto, Akitsugu| Omote, Hiroshi| Moriyama, Yoshinori| |
|---|---|
| Published Date | 2014-10-30 |
| Publication Title | Scientific Reports |
| Volume | volume4 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/52901 |
|---|---|
| FullText URL | 68_5_313.pdf |
| Author | Yamane, Kentaro| Tanaka, Masato| Sugimoto, Yoshihisa| Ichimura, Kouichi| Ozaki, Toshifumi| |
| Abstract | Ossified meningioma is classified histologically as a phenotype of metaplastic meningioma, and it is extremely rare. There are only 12 cases involving ossified spinal meningiomas in the literature. We present the case of a 61-year-old female with a primary tumor within the ventral spinal canal at T12. Although we performed a total tumor excision using an ultrasonic bone aspirator, a temporary deterioration of motor evoked potentials (MEPs) was observed during curettage with a Kerrison rongeur. The neurologic findings worsened immediately after surgery. Histologically, the tumor was diagnosed as a metaplastic meningioma with osseous differentiation. In order to avoid spinal cord injury, great care must be taken when removing an ossified meningioma located on the ventral spinal cord. |
| Keywords | spinal metaplastic meningioma osseous differentiation ossified meningioma ultrasonic bone aspirator post-operative course |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-10 |
| Volume | volume68 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 313 |
| End Page | 316 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25338489 |
| Web of Science KeyUT | 000343269300009 |
| JaLCDOI | 10.18926/AMO/52900 |
|---|---|
| FullText URL | 68_5_307.pdf |
| Author | Muro, Shinichiro| Nasu, Junichiro| Harada, Ryo| Matsubara, Minoru| Nakarai, Asuka| Kanzaki, Hiromitsu| Tsutsumi, Kouichiro| Kato, Hironari| Tanaka, Takehiro| Fujiwara, Hiroyasu| Uno, Masatoshi| Okada, Hiroyuki| Yamamoto, Kazuhide| |
| Abstract | A 45-year-old female who presented with loss of consciousness and a cold sweat was found to have a pancreatic tumor and multiple liver metastases. Laboratory studies showed marked hypoglycemia and inappropriately elevated serum insulin, C-peptide, and serum tumor markers. Fine needle aspiration revealed Grade 3 small-cell type primary pancreatic neuroendocrine carcinoma. Consequently, the diagnosis of malignant insulinoma was made. Transarterial embolization (TAE) for hepatic metastases resulted in the reduction of tumor volume and prompt resolution of hypoglycemic attacks, whereas diazoxide and systemic chemotherapy had been ineffective for controlling blood glucose levels, and octreotide was unavailable due to the allergic effect. This case report highlights the potential usefulness of TAE for malignant insulinomas in the management of hypoglycemia. |
| Keywords | malignant insulinoma hypoglycemia liver metastases transarterial embolization neuroendocrinetumor |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-10 |
| Volume | volume68 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 307 |
| End Page | 311 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25338488 |
| Web of Science KeyUT | 000343269300008 |
| JaLCDOI | 10.18926/AMO/52898 |
|---|---|
| FullText URL | 68_5_291.pdf |
| Author | Tsuzaki, Ryuichiro| Takaki, Akinobu| Yagi, Takahito| Ikeda, Fusao| Koike, Kazuko| Iwasaki, Yoshiaki| Shiraha, Hidenori| Miyake, Yasuhiro| Sadamori, Hiroshi| Shinoura, Susumu| Umeda, Yuzo| Yoshida, Ryuichi| Nobuoka, Daisuke| Utsumi, Masashi| Nakayama, Eiichi| Fujiwara, Toshiyoshi| Yamamoto, Kazuhide| |
| Abstract | It is not known how the immune system targets hepatitis C virus (HCV)-infected HLA-mismatched hepatocytes under immune-suppressed conditions after orthotopic liver transplantation (OLT). In addition, the relationship between the HCV-specific immune response and IL28B variants as predictors of HCV clearance has not been well-characterized. We determined the IL28B polymorphisms for 57 post-OLT HCV carriers, and we assessed the HCV-specific immune responses by measuring the peripheral blood mononuclear cell-derived HCV-specific interferon-gamma (IFN-γ) response using an enzyme-linked immunospot assay. At 1-3 years after OLT, patients with no active hepatitis showed higher total spots on the immunospot assay. At＞3 years after OLT, patients with resolved HCV showed higher levels of core, NS3, NS5A, and total spots compared to the chronic hepatitis patients. The IL28B major genotype in the donors correlated with higher spot counts for NS5A and NS5B proteins at 1-3 years after OLT. In the post-OLT setting, the HCV-specific immune response could be strongly induced in patients with no active hepatitis with an IL28B major donor or sustained virological response. Strong immune responses in the patients with no active hepatitis could only be maintained for 3 years and diminished later. It may be beneficial to administer IFN treatment starting 3 years after OLT, to induce the maximum immunological effect. |
| Keywords | interferon gamma ELISPOT assay single nucleotide polymorphisms dendritic cell CD4 T cell |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-10 |
| Volume | volume68 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 291 |
| End Page | 302 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25338486 |
| Web of Science KeyUT | 000343269300006 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/53129 |
| Author | MINOWA, Hirotsugu| MUNESAWA, Yoshiomi| |
|---|---|
| Published Date | 2014-10-15 |
| Publication Title | 安全工学 |
| Volume | volume53 |
| Issue | issue5 |
| Content Type | Journal Article |
| Author | Kaneko, Makoto| |
|---|---|
| Published Date | 2014-07-31 |
| Publication Title | 岡山大学文学部プロジェクト研究報告書 |
| Volume | volume22 |
| Content Type | Research Paper |
| FullText URL | PLOSONE_9_9_e107976.pdf |
|---|---|
| Author | Shigehiro, Tsukasa| Kasai, Tomonari| Murakami, Masaharu| Sekhar, Sreeja C.| Tominaga, Yuki| Okada, Masashi| Kudoh, Takayuki| Mizutani, Akifumi| Murakami, Hiroshi| Salomon, David S.| Mikuni, Katsuhiko| Mandai, Tadakatsu| Hamada, Hiroki| Seno, Masaharu| |
| Published Date | 2014-09-29 |
| Publication Title | PLoS ONE |
| Volume | volume9 |
| Issue | issue9 |
| Publisher | Public Library Science |
| Start Page | e107976 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 25264848 |
| DOI | 10.1371/journal.pone.0107976 |
| Web of Science KeyUT | 000345745400036 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0107976 |
| Author | 曽我 賢彦| |
|---|---|
| Published Date | 2012-06 |
| Publication Title | 日本歯科評論 |
| Volume | volume72 |
| Issue | issue6 |
| Content Type | Article |
| Author | Kikuchi, Hiroshi| Shiozawa, Nobuyoshi| Takata, Shingo| Ashida, Kozo| Mitsunobu, Fumihiro| |
|---|---|
| Published Date | 2013-12-12 |
| Publication Title | International Journal of Chronic Obstructive Pulmonary Disease |
| Volume | volume9 |
| Content Type | Journal Article |
