result 677 件
| FullText URL | K0005094 abstract_review.pdf K0005094_fulltext.pdf |
|---|---|
| Author | Miyake, Tomoko| |
| Published Date | 2015-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5094号 |
| Granted Date | 2015-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0005083 abstract_review.pdf K0005083_fulltext.pdf |
|---|---|
| Author | Kubota, Yasuhiro| |
| Published Date | 2015-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5083号 |
| Granted Date | 2015-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | O0004435_abstract_review.pdf O0004435_fulltext.pdf |
|---|---|
| Author | Osumi, Yoshihiro| |
| Published Date | 2015-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4435号 |
| Granted Date | 2015-03-25 |
| Thesis Type | Doctor of Philosophy in Engineering |
| Grantor | 岡山大学 |
| language | Japanese |
| JaLCDOI | 10.18926/AMO/53340 |
|---|---|
| FullText URL | 69_2_113.pdf |
| Author | Inada, Ryo| Nagasaka, Takeshi| Toshima, Toshiaki| Mori, Yoshiko| Kondo, Yoshitaka| Kishimoto, Hiroyuki| Hiraki, Takao| Oshiro, Taihei| Kanemitsu, Yukihide| Fujiwara, Toshiyoshi| |
| Abstract | A case of advanced rectal cancer treated by aggressive local and systemic treatment who has survived more than 7 years from initial recurrence is presented. A 55-year-old woman was diagnosed with advanced lower rectal cancer and underwent a low anterior resection with complete removal of all regional lymph nodes and total mesorectal excision. The tumor was diagnosed as a moderately differentiated adenocarcinoma, pStage IIIB (T3, N2a, M0). Twenty-six months after the initial surgery, local recurrence in the pelvis was detected by computed tomography, and total pelvic exenteration with distal sacrectomy (TPES) was performed after systemic chemotherapy with a molecular-targeted drug. Six months after the TPES, multiple lung metastases were detected. Consequently, the patient underwent radiofrequency ablation (RFA) and chemotherapy. The disease has since been controlled for 38 months. As volume control is essential for cancer treatment, it may be important to combine appropriate local therapy with systemic therapy to metastatic or recurrent sites in order to achieve much longer disease control. |
| Keywords | colorectal cancer recurrence total pelvic exenteration radiofrequency ablation systemic chemotherapy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-04 |
| Volume | volume69 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 113 |
| End Page | 118 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25899633 |
| Web of Science KeyUT | 000353181700006 |
| JaLCDOI | 10.18926/AMO/53338 |
|---|---|
| FullText URL | 69_2_95.pdf |
| Author | Lee, Mi Geum| Lee, Dong Kyu| Huh, Billy K.| Choi, Sang Sik| Kim, Hee Zoo| Lim, Byung Gun| Kim, Hong Soon| Choi, Yun Suk| Hur, Won Seok| Lee, Mi Kyoung| |
| Abstract | Resiniferatoxin (RTX) is an ultrapotent synthetic TRPV1 (transient receptor potential vanilloid subtype 1) agonist with significant initial transient hyperalgesia followed by a prolonged analgesic effect in response to thermal stimulus. Using a rat model of neuropathic pain, we evaluated the effect of pretreatment with clonidine－which has been shown to relieve intradermal capsaicin-induced hyperalgesia－on the initial hyperalgesic response and the thermal analgesic property of RTX. Thirty-six male rats were divided into 6 treatment groups (n＝6 each):RTX 500ng, RTX 1μg, clonidine 20μg (Cl), Cl＋RTX 500ng, Cl＋RTX 1μg, or normal saline 20μL (control). We evaluated the short-term (180min) and long-term (20 days) analgesic effects of RTX after thermal stimulation and mechanical stimulation. RTX had significant initial transient hyperalgesia followed by a prolonged analgesic effect in response to the thermal stimulus, but the RTX 500ng and RTX 1μg groups showed no initial short-term thermal hyperalgesic responses when pretreated with clonidine. The Cl＋RTX 1μg ratsʼ behavior scores indicated that they were more calm and comfortable compared to the RTX 1μg rats. Even though we cannot precisely confirm that pretreatment with clonidine potentiates or adds to the analgesic effect of RTX, clonidine pretreatment with epidural RTX eliminated the initial RTX-associated hyperalgesic response and systemic toxicity in this neuropathic pain rat model. |
| Keywords | clonidine epidural administration resiniferatoxin spinal nerve ligation rat model thermal hyperalgesia |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-04 |
| Volume | volume69 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 95 |
| End Page | 103 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25899631 |
| Web of Science KeyUT | 000353181700004 |
| JaLCDOI | 10.18926/AMO/53335 |
|---|---|
| FullText URL | 69_2_71.pdf |
| Author | Hiramoto, Hiroki| Dansako, Hiromichi| Takeda, Midori| Satoh, Shinya| Wakita, Takaji| Ikeda, Masanori| Kato, Nobuyuki| |
| Abstract | Persistent infection with hepatitis C virus (HCV) often causes chronic hepatitis, and then shows a high rate of progression to liver cirrhosis and hepatocellular carcinoma. To clarify the mechanism of the persistent HCV infection is considered to be important for the discovery of new target(s) for the development of anti-HCV strategies. In the present study, we found that the expression level of annexin A1 (ANXA1) in human hepatoma cell line Li23-derived D7 cells was remarkably lower than that in parental Li23 cells, whereas the susceptibility of D7 cells to HCV infection was much higher than that of Li23 cells. Therefore, we hypothesized that ANXA1 negatively regulates persistent HCV infection through the inhibition of viral RNA replication. The results revealed that HCV production was significantly inhibited without a concomitant reduction in the amount of lipid droplets in the D7 cells stably expressing exogenous ANXA1. Further, we demonstrated that ANXA1 negatively regulated the step of viral RNA replication rather than that of viral entry in human hepatocytes. These results suggest that ANXA1 would be a novel target for the development of anti-HCV strategies. |
| Keywords | HCV annexin A1 Li23 cell line Li23-derived D7 cells HCV-JFH-1 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-04 |
| Volume | volume69 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 71 |
| End Page | 78 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25899628 |
| Web of Science KeyUT | 000353181700001 |
| JaLCDOI | 10.18926/fest/53217 |
|---|---|
| FullText URL | fest_020_001_011.pdf |
| Author | Ichiminami, Fumikazu| Noguchi, Yukiko| Dinçsoy, Meltem Okur| Dinçsoy, Enver Erdinç| |
| Abstract | This study investigated the civil consciousness on the preserved trees in Himeji city, Hyogo prefecture. We conducted data collection in the city hall,,observed preserved trees, and examined the awareness of citizens against the preserved trees in the central area and Syosya-zan Engyo-ji. As a result, it was revealed that the citizens are not indifferent to the natural environment of trees, etc., they also do not have a strong interest in it in particular. As for preserved tree system, there were some slight differences in the recog -nition between the people who actually take care of trees and administration. People are in favor of the need for the current system of preserved trees. However, in Japan, which is blessed with many things, people do not recognize strongly appreciating the natural environment. |
| Keywords | preserved tree ordinance civil consciousness Himeji city |
| Publication Title | 岡山大学環境理工学部研究報告 |
| Published Date | 2015-03 |
| Volume | volume20 |
| Issue | issue1 |
| Start Page | 1 |
| End Page | 11 |
| ISSN | 2187-6940 |
| language | English |
| File Version | publisher |
| NAID | 120005572532 |
| JaLCDOI | 10.18926/53179 |
|---|---|
| FullText URL | bhe_010_123_134.pdf |
| Author | Lamitie, Robert| |
| Abstract | Four first-year university Listening classes, consisting of 158 students, were given a unit in which they were asked to listen to one episode per week of a popular English episodic television program for homework and to write reaction papers. The purpose was to evaluate whether the unit seemed to improve their listening and their English competence, and to see if the students were interested enough by the shows that they would continue watching the programs on their own afterwards. Students were given questionnaires after the end of the unit, and they felt that the unit had improved their competence. 76% indicated that they intended to continue watching their show, revealing genuine interest. |
| Keywords | motivation input hooked recreation TV programs |
| Publication Title | 大学教育研究紀要 |
| Published Date | 2014-12 |
| Volume | volume10 |
| Start Page | 123 |
| End Page | 134 |
| ISSN | 1881-5952 |
| language | English |
| File Version | publisher |
| NAID | 120005567861 |
| FullText URL | K0005073_abstract_review.pdf K0005073_fulltext.pdf |
|---|---|
| Author | Hirayama, Takahiro| |
| Published Date | 2014-12-31 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5073号 |
| Granted Date | 2014-12-31 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| JaLCDOI | 10.18926/53052 |
|---|---|
| Title Alternative | The Never-Ending Narration: Paul Auster’s “Leviathan” and the Three Narrators |
| FullText URL | hss_038_017_036.pdf |
| Author | Nakatani, Hitomi| |
| Publication Title | 岡山大学大学院社会文化科学研究科紀要 |
| Published Date | 2014-11-26 |
| Volume | volume38 |
| Start Page | 17 |
| End Page | 36 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | Copyright © 2014 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120005526629 |
| JaLCDOI | 10.18926/AMO/53021 |
|---|---|
| FullText URL | 68_6_323.pdf |
| Author | Hirayama, Takahiro| Nagano, Osamu| Shiba, Naoki| Yumoto, Tetsuya| Sato, Keiji| Terado, Michihisa| Ugawa, Toyomu| Ichiba, Shingo| Ujike, Yoshihito| |
| Abstract | In adult high-frequency oscillatory ventilation (HFOV), stroke volume (SV) and mean lung pressure (PLung) are important for lung protection. We measured the airway pressure at the Y-piece and the lung pressure during HFOV using a lung model and HFOV ventilators for adults (R100 and 3100B). The lung model was made of a 20-liter, airtight rigid plastic container (adiabatic compliance: 19.3ml/cmH2O) with or without a resistor (20cmH2O/l/sec). The ventilator settings were as follows: mean airway pressure (MAP), 30cmH2O;frequency, 5-15Hz (every 1Hz);airway pressure amplitude (AMP), maximum;and % of inspiratory time (IT), 50% for R100, 33% or 50% for 3100B. The measurements were also performed with an AMP of 2/3 or 1/3 maximum at 5, 10 and 15Hz. The PLung and the measured MAP were not consistently identical to the setting MAP in either ventilator, and decreasing IT decreased the PLung in 3100B. In conclusion, we must pay attention to the possible discrepancy between the PLung and the setting MAP during adult HFOV. |
| Keywords | HFOV mean lung pressure mean airway pressure |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-12 |
| Volume | volume68 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 323 |
| End Page | 329 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25519026 |
| Web of Science KeyUT | 000346882200002 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/53132 |
| Author | Mazaki, Tetsuro| Shiozaki, Yasuyuki| Yamane, Kentaro| Yoshida, Aki| Nakamura, Mariko| Yoshida, Yasuhiro| Zhou, Di| Kitajima, Takashi| Tanaka, Masato| Ito, Yoshihiro| Ozaki, Toshifumi| Matsukawa, Akihiro| |
|---|---|
| Published Date | 2014-03-25 |
| Publication Title | Scientific Reports |
| Volume | volume4 |
| Content Type | Journal Article |
| FullText URL | K0005057_abstract_review.pdf K0005057_fulltext.pdf |
|---|---|
| Author | 李 暁剛| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5057号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005033_abstract_review.pdf K0005033_fulltext.pdf |
|---|---|
| Author | Mazaki, Tetsuro| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5033号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | Arata, T| Okitsu, T| Fukazawa, T| Ikeda, H| Kobayashi, K| Yong, C| Kosaka, Y| Narushima, M| Matsuoka, J| Yamamoto, I| Tanaka, N| Lakey, JRT| Kobayashi, N| |
|---|---|
| Published Date | 2004-06 |
| Publication Title | Artificial Organs |
| Volume | volume28 |
| Issue | issue6 |
| Content Type | Journal Article |
| Author | Iwatani, Kayoko| Takata, Katsuyoshi| Sato, Yasuharu| Miyata-Takata, Tomoko| Iwaki, Noriko| Cui, Wei| Sawada-Kitamura, Seiko| Sonobe, Hiroshi| Tamura, Maiko| Saito, Katsuhiko| Miyatani, Katsuya| Yamasaki, Rie| Yamadori, Ichiro| Fujii, Nobuharu| Terasaki, Yasushi| Maeda, Yoshinobu| Tanimoto, Mitsune| Nakamura, Naoya| Yoshino, Tadashi| |
|---|---|
| Published Date | 2014-07 |
| Publication Title | Human Pathology |
| Volume | volume45 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Nagataki, Hiroyuki| Nakano, Yoshiaki| Nobe, Midori| Tohyama, Tatsuya| Kanemune, Susumu| |
|---|---|
| Published Date | 2013-11 |
| Publication Title | Proceedings of 8th Workshop in Primary and Secondary Computing Education |
| Content Type | Conference Paper |
| FullText URL | O0004426_abstract_review.pdf O0004426_fulltext.pdf |
|---|---|
| Author | Arata, Takashi| |
| Published Date | 2014-06-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4426号 |
| Granted Date | 2014-06-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005019_abstract_review.pdf K0005019_fulltext.pdf |
|---|---|
| Author | Iwatani, Kayoko| |
| Published Date | 2014-06-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5019号 |
| Granted Date | 2014-06-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | Nishikawa, Hitoshi| Oto, Takahiro| Otani, Shinji| Harada, Masaaki| Iga, Norichika| Miyoshi, Kentaroh| Miyoshi, Shinichiro| |
|---|---|
| Published Date | 2013-12 |
| Publication Title | The Journal of Thoracic and Cardiovascular Surgery |
| Volume | volume146 |
| Issue | issue6 |
| Content Type | Journal Article |
