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ID 31942
JaLCDOI
FullText URL
Author
Nakamoto, Shu
Sadahira, Yoshito
Mori, Masaharu
Awai, Michiyasu
Abstract

We investigated the organ distribution of four types of red blood cells (RBC) preparations: native RBC, asialo-RBC, native ghosts and asialo-ghosts. Intravenously injected asialo-ghosts were rapidly removed from the blood stream and accumulated mainly in the liver 120 min after the injection. Our results suggest that asialo-ghosts are a simple and effective carrier for targeting of drugs to the liver.

Keywords
red blood cell ghosts
sialidase-treatment
orgam distribution
targeting to liver.
Amo Type
Article
Publication Title
Acta Medica Okayama
Published Date
1986-02
Volume
volume40
Issue
issue1
Publisher
Okayama University Medical School
Start Page
61
End Page
64
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT