result 48592 件
| JaLCDOI | 10.18926/AMO/63203 |
|---|---|
| FullText URL | 76_1_7.pdf |
| Author | Takami, Masao| Yamamoto, Koichiro| Hanayama, Yoshihisa| Nakano, Yasuhiro| Hasegawa, Kou| Obika, Mikako| Hagiya, Hideharu| Furukawa, Masanori| Otsuka, Fumio| |
| Abstract | Subclinical hypothyroidism (SCH) is diagnosed when serum thyrotropin (TSH) is elevated despite a normal thyroxine level and is known to increase the risk of metabolic disorders. This study was conducted to identify potential laboratory markers suspicious for latent SCH. We retrospectively reviewed 958 outpatients in whom thyroid functions had been examined. Eighty-five (9.1%) of the 939 analyzed subjects had SCH (73% females). In the SCH group, median serum TSH and FT4 levels were 5.04 μU/ml and 1.19 ng/dl, respectively, and auto-thyroid antibodies were detected in 53.8% of patients. SCH group patients were significantly older than patients in the euthyroid group, while there was no intergroup difference in BMI. However, 56.5% of the SCH patients were asymptomatic. In the SCH group, serum aspartate aminotransferase and low-density lipoprotein cholesterol (LDL-C) levels were significantly higher, and the estimated glomerular filtration rate (eGFR) was significantly lower than in the euthyroid group. Among patients less than 65 years of age, SCH patients tended to have lower eGFR and higher LDL-C than euthyroid patients. Age-dependent reductions of red blood cells and serum albumin were more prominent in the SCH than the euthyroid group. Biochemical changes with aging are useful as potential clues for suspecting latent SCH. |
| Keywords | aging renal function cholesterol subclinical hypothyroidism thyroid function |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 7 |
| End Page | 15 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35236993 |
| Web of Science KeyUT | 000762812700002 |
| JaLCDOI | 10.18926/AMO/63202 |
|---|---|
| FullText URL | 76_1_1.pdf |
| Author | Takao, Tomoka| Yamada, Daisuke| Takarada, Takeshi| |
| Abstract | Optogenetics, a technology to manipulate biological phenomena thorough light, has attracted much attention in neuroscience. Recently, the Magnet System, a photo-inducible protein dimerization system which can control the intracellular behavior of various biomolecules with high accuracy using light was developed. Furthermore, photoactivation systems for controlling biological phenomena are being developed by combining this technique with genome-editing technology (CRISPR/Cas9 System) or DNA recombination technology (Cre-loxP system). Herein, we review the history of optogenetics and the latest Magnet System technology and introduce our recently developed photoactivatable Cre knock-in mice with temporal-, spatial-, and cell-specific accuracy. |
| Keywords | optogenetics Cre recombinase |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 1 |
| End Page | 5 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35236992 |
| Web of Science KeyUT | 000762812700001 |
| FullText URL | fulltext20220216-4.pdf |
|---|---|
| Author | Nomura, Emi| Kawahara, Yuko| Omote, Yoshio| Takahashi, Yoshiaki| Matsumoto, Namiko| Ikegami, Ken| Takemoto, Mami| Hishikawa, Nozomi| Nakano, Yumiko| Yunoki, Taijun| Morihara, Ryuta| Uemura, Masahiro| Abe, Koji| Yamashita, Toru| |
| Keywords | ATP-binding cassette subfamily C member 6 (ABCC6) neurovascular diseases pseudoxanthoma elasticum (PXE) |
| Note | This is the peer reviewed version of the following article: [Nomura, E, Kawahara, Y, Omote, Y, et al. A case of a heterozygous ABCC6 mutation showing recurrent ischemic strokes and intracranial hemorrhages. Neurol Clin Neurosci. 2022; 00: 1– 4. doi:10.1111/ncn3.12575], which has been published in final form at https://doi.org/10.1111/ncn3.12575. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| Published Date | 2022-2-4 |
| Publication Title | Neurology and Clinical Neuroscience |
| Volume | volume10 |
| Publisher | Wiley |
| Start Page | 98 |
| End Page | 101 |
| ISSN | 2049-4173 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1111/ncn3.12575 |
| Web of Science KeyUT | 000750987400001 |
| Related Url | isVerisonOf https://doi.org/10.1111/ncn3.12575 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nagasaki, Joji| Inozume, Takashi| Sax, Nicolas| Ariyasu, Ryo| Ishikawa, Masakazu| Yamashita, Kazuo| Kawazu, Masahito| Ueno, Toshihide| Irie, Takuma| Tanji, Etsuko| Morinaga, Takao| Honobe, Akiko| Ohnuma, Takehiro| Yoshino, Mitsuru| Iwata, Takekazu| Kawase, Katsushige| Sasaki, Keita| Hanazawa, Toyoyuki| Kochin, Vitaly| Kawamura, Tatsuyoshi| Matsue, Hiroyuki| Hino, Masayuki| Mano, Hiroyuki| Suzuki, Yutaka| Nishikawa, Hiroyoshi| Togashi, Yosuke| |
| Published Date | 2022-02-01 |
| Publication Title | Cell Reports |
| Volume | volume38 |
| Issue | issue5 |
| Publisher | Cell Press |
| Start Page | 110331 |
| ISSN | 2211-1247 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Author(s). |
| File Version | publisher |
| PubMed ID | 35108529 |
| DOI | 10.1016/j.celrep.2022.110331 |
| NAID | 120007192058 |
| Web of Science KeyUT | 000750983700001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.celrep.2022.110331 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Higo, Hisao| Ohashi, Kadoaki| Tomida, Shuta| Okawa, Sachi| Yamamoto, Hiromasa| Sugimoto, Seiichiro| Senoo, Satoru| Makimoto, Go| Ninomiya, Kiichiro| Nakasuka, Takamasa| Nishii, Kazuya| Taniguchi, Akihiko| Kubo, Toshio| Ichihara, Eiki| Hotta, Katsuyuki| Miyahara, Nobuaki| Maeda, Yoshinobu| Toyooka, Shinichi| Kiura, Katsuyuki| |
| Keywords | Idiopathic pulmonary fibrosis RNA sequencing Molecular therapeutic target Personalized therapy |
| Published Date | 2022-02-07 |
| Publication Title | Respiratory Research |
| Volume | volume23 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 20 |
| ISSN | 1465-993X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022. |
| File Version | publisher |
| PubMed ID | 35130915 |
| DOI | 10.1186/s12931-022-01940-y |
| Web of Science KeyUT | 000752386100002 |
| Related Url | isVersionOf https://doi.org/10.1186/s12931-022-01940-y |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Fujita, Claudia| Akhtar, M. Shahbaz| Hidaka, Ray| Nishigaki, Makoto| |
| Keywords | Dissolved iron removal Chemical clogging Open-loop geothermal systems Retention potential Wooden charcoal |
| Published Date | 2022-02-07 |
| Publication Title | Applied Water Science |
| Volume | volume12 |
| Issue | issue3 |
| Publisher | SPRINGER HEIDELBERG |
| Start Page | 30 |
| ISSN | 2190-5487 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| DOI | 10.1007/s13201-022-01574-x |
| Web of Science KeyUT | 000752014000004 |
| Related Url | isVersionOf https://doi.org/10.1007/s13201-022-01574-x |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Oda, Shinsuke| Fujisawa, Masayoshi| Li, Chunning| Ito, Toshihiro| Yamaguchi, Takahiro| Yoshimura, Teizo| Matsukawa, Akihiro| |
| Published Date | 2021-11-24 |
| Publication Title | Plos One |
| Volume | volume16 |
| Issue | issue11 |
| Publisher | Public Library Science |
| Start Page | e0254289 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Oda et al. |
| File Version | publisher |
| PubMed ID | 34818323 |
| DOI | 10.1371/journal.pone.0254289 |
| Web of Science KeyUT | 000747234800004 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0254289 |
| FullText URL | fulltext20220216-3.pdf Figure20220216-3.pdf Supplementary Figure20220216-3.pdf |
|---|---|
| Author | Nishimura, Yoshito| Hagiya, Hideharu| Keitoku, Koichi| Koyama, Toshihiro| Otsuka, Fumio| |
| Note | © 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.ajic.2021.08.033] .| |
| Published Date | 2022-01-28 |
| Publication Title | American Journal of Infection Control |
| Volume | volume50 |
| Issue | issue2 |
| Publisher | Elsevier BV |
| Start Page | 141 |
| End Page | 147 |
| ISSN | 0196-6553 |
| NCID | AA10617749 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Association for Professionals in Infection Control and Epidemiology, Inc. |
| File Version | author |
| PubMed ID | 34718066 |
| DOI | 10.1016/j.ajic.2021.08.033 |
| Web of Science KeyUT | 000749317500004 |
| Related Url | isVersionOf https://doi.org/10.1016/j.ajic.2021.08.033 |
| FullText URL | fulltext20220216-2.pdf |
|---|---|
| Author | Thi Cam, Nguyen| Sunagawa, Naomichi| Sesumi, Miho| Kitamura, Yoshikuni| Tanaka, Yoshiyuki| Goto, Tanjuro| Yasuba, Ken-ichiro| Yoshida, Yuichi| |
| Published Date | 2022-01-22 |
| Publication Title | The Horticulture Journal |
| Volume | volume91 |
| Issue | issue1 |
| Publisher | Japanese Society for Horticultural Science |
| Start Page | 58 |
| End Page | 67 |
| ISSN | 2189-0102 |
| NCID | AA12708073 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Japanese Society for Horticultural Science (JSHS) |
| File Version | publisher |
| DOI | 10.2503/hortj.utd-315 |
| NAID | 120007193740 |
| Web of Science KeyUT | 000749466800001 |
| Related Url | isVersionOf https://doi.org/10.2503/hortj.utd-315 |
| FullText URL | fulltext20220216-1.pdf |
|---|---|
| Author | Khan, Haris Ahmed| Sato, Yukiyo| Kondo, Hideki| Jamal, Atif| Bhatti, Muhammad Faraz| Suzuki, Nobuhiro| |
| Note | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00705-021-05304-7| |
| Published Date | 2022-02-03 |
| Publication Title | Archives of Virology |
| Volume | volume167 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 923 |
| End Page | 929 |
| ISSN | 0304-8608 |
| NCID | AA00548901 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature 2022 |
| File Version | author |
| PubMed ID | 35112205 |
| DOI | 10.1007/s00705-021-05304-7 |
| Web of Science KeyUT | 000749980300010 |
| Related Url | isVersionOf 1https://doi.org/0.1007/s00705-021-05304-7 |
| FullText URL | fulltext20220208-1.pdf |
|---|---|
| Author | Onishi, Yasuhiro| Mise, Koki| Kawakita, Chieko| Uchida, Haruhito A.| Sugiyama, Hitoshi| Sugawara, Ryosuke| Yamaguchi, Satoshi| Yoshida, Michihiro| Mitsuhashi, Toshiharu| Yamada, Masao| Hirabayashi, Jun| Wada, Jun| |
| Keywords | Glomerulonephritis IgA nephropathy Diagnostic biomarkers Lectins Glycomics |
| Note | This is an Accepted Manuscript published by S. Karger AG.| |
| Published Date | 2021-12-29 |
| Publication Title | American Journal of Nephrology |
| Volume | volume53 |
| Issue | issue1 |
| Publisher | S. Karger AG |
| Start Page | 10 |
| End Page | 20 |
| ISSN | 0250-8095 |
| NCID | AA10424676 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 S. Karger AG, Basel |
| File Version | author |
| PubMed ID | 34965524 |
| DOI | 10.1159/000520998 |
| Web of Science KeyUT | 000747743400001 |
| Related Url | isVersionOf https://doi.org/10.1159/000520998 |
| Title Alternative | Report of the 39th Annual Meeting of the Japanese Liver Transplantation Society |
|---|---|
| FullText URL | 133_200.pdf |
| Author | Yagi, Takahito| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 200 |
| End Page | 201 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.200 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.200 |
| Title Alternative | The 45th Annual Meeting of the Japanese Society of Lymphology |
|---|---|
| FullText URL | 133_198.pdf |
| Author | Kimata, Yoshihiro| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 198 |
| End Page | 199 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.198 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.198 |
| NAID | 130008139620 |
| Title Alternative | Telemedicine in cardiovascular surgery |
|---|---|
| FullText URL | 133_195.pdf |
| Author | Kasahara, Shingo| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 195 |
| End Page | 197 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.195 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.195 |
| Title Alternative | Drug interaction (52. Drug interaction with diuretics) |
|---|---|
| FullText URL | 133_189.pdf |
| Author | Takeda, Tatsuaki| Esumi, Satoru| Murakawa, Kiminaka| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 189 |
| End Page | 194 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.189 |
| language | English |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.189 |
| Title Alternative | AI research in dentistry and related clinical-study design |
|---|---|
| FullText URL | 133_184.pdf |
| Author | Kimura-Ono, Aya| Kuboki, Takuo| |
| Keywords | 人工知能 歯科 臨床研究デザイン |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 184 |
| End Page | 188 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.184 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.184 |
| NAID | 130008139622 |
| Title Alternative | AI in dentistry and clues for starting AI research |
|---|---|
| FullText URL | 133_181.pdf |
| Author | Kodama, Naoki| Sugimoto, Hikaru| Minagi, Shogo| |
| Keywords | 人工知能 歯科 咀嚼 |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 181 |
| End Page | 183 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.181 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.181 |
| NAID | 130008139623 |
| Title Alternative | Four types of duodenal white lesions (follicular lymphoma, lymphoid hyperplasia, lymphangiectasia, and lymphangioma) : A case report |
|---|---|
| FullText URL | 133_175.pdf |
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Okada, Hiroyuki| |
| Abstract | A 70-year-old Japanese man underwent esophagogastroduodenoscopy that revealed multiple whitish duodenal granules. The histopathological analysis of the biopsied specimen led to the diagnosis of duodenal-type follicular lymphoma. The lesion showed spontaneous improvement ; however, 14 months later a few small whitish granules were observed by esophagogastroduodenoscopy. Observation under magnification revealed slightly elevated opaque white spots and whitish granular protrusions of roughly the same size that were uniformly distributed in the duodenal bulb. The duodenal bulb lesions were histopathologically diagnosed as lymphoid hyperplasia. The patient also exhibited lymphangiectasia (which presented as scattered white spots) and lymphangioma (which presented as a soft submucosal tumor with white spots on the surface) in the second portion of the duodenum. This patient presented with four white lesions in the duodenum : duodenal-type follicular lymphoma, lymphoid hyperplasia, lymphangiectasia, and lymphangioma. Careful endoscopic evaluation enabled a prompt diagnosis in this case. |
| Keywords | 十二指腸濾胞性リンパ腫（duodenal-type follicular lymphoma） リンパ濾胞過形成（lymphoid hyperplasia） リンパ管腫（lymphangioma） リンパ管拡張（lymphangiectasia） |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 175 |
| End Page | 180 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.175 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.175 |
| Title Alternative | The difficulty of understanding psychiatry : Thoughts from studentsʼ questions |
|---|---|
| FullText URL | 133_169.pdf |
| Author | Yamada, Norihito| |
| Keywords | 精神疾患の診断 バイオマーカー 理念型 大学病院精神科 |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 169 |
| End Page | 174 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.169 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.169 |
| Title Alternative | Establishment of a new disease entity : Duodenal-type follicular lymphoma |
|---|---|
| FullText URL | 133_166.pdf |
| Author | Yoshino, Tadashi| |
| Keywords | リンパ腫 濾胞性リンパ腫 疾患単位 |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 166 |
| End Page | 168 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.166 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.166 |
