result 47942 件
| JaLCDOI | 10.18926/AMO/62398 |
|---|---|
| FullText URL | 75_4_461.pdf |
| Author | Murakami, Hiroyuki| Yoshioka, Takanori| Moriyama, Takashi| Ishikawa, Tatsunori| Makita, Masanori| Sunami, Kazutaka| |
| Abstract | Bendamustine plus rituximab (B-R) is an effective therapy for relapsed or refractory (r/r) low-grade B-cell lymphoma (LGBCL) and mantle cell lymphoma (MCL); however, clinical data from Japanese patients treated with B-R therapy are limited. We retrospectively evaluated the efficacy and safety of B-R therapy in 42 patients who received B-R therapy at our hospital for r/r LGBCL and MCL. All patients received intravenous (IV) ritux-imab 375 mg/m2 on day 1 and IV bendamustine 90 mg/m2 on days 2 and 3 every 28 days for up to 6 cycles. The common histologic subtypes were follicular lymphoma (n = 29, 70%), marginal zone lymphoma (n = 6, 14%), and MCL (n = 5, 12%). The overall response rate was 93%, with 62% complete response and complete response unconfirmed. The median progression-free survival (PFS) was 38 months (95% confidence interval [CI], 24.6 to not reached [NR]), and the median overall survival (OS) was 80 months (95% CI, 60.7 to NR). Patients receiving a cumulative dose of bendamustine ≥ 720 mg/m2 showed a significantly longer PFS and OS. Grade 3/4 adverse events (≥ 10%) included neutropenia (55%), lymphopenia (69%), and nausea (24%). B-R therapy was effective and well tolerated, and the cumulative dose of bendamustine was associated with a favorable outcome. |
| Keywords | bendamustine low grade B-cell lymphoma mantle cell lymphoma |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 461 |
| End Page | 469 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511613 |
| Web of Science KeyUT | 000697944600008 |
| NAID | 120007146041 |
| JaLCDOI | 10.18926/AMO/62397 |
|---|---|
| FullText URL | 75_4_455.pdf |
| Author | Muraoka, Sosuke| Yamane, Kentaro| Misawa, Haruo| Takigawa, Tomoyuki| Tetsunaga, Tomoko| Oda, Yoshiaki| Nakanishi, Kazuo| Ozaki, Toshifumi| Tanaka, Takehiro| |
| Abstract | The intraoperative pathological diagnosis (IPD) plays an important role in determining the optimal surgical treatment for spinal cord tumors. The final pathological diagnosis (FPD) is sometimes different from the IPD. Here, we sought to identify the accuracy of the IPD of spinal cord tumors compared to the FPD. We retrospec-tively analyzed the cases of 108 patients with spinal cord tumors treated surgically in our institute; the IPD, FPD, mismatched cases, and concordance rate between the IPD and FPD were investigated. Five cases involved a mismatch between the IPD and FPD. The overall concordance rate was 95.4%, with 90.9% for extra-dural lesions, 98.5% for intradural extramedullary lesions, 84.2% for intramedullary lesions, and 100% for dumbbell-type tumors. The concordance rate of intramedullary lesions tended to be lower than that of other lesions (p = 0.096). A lower concordance rate was revealed for intramedullary lesions compared to the other lesions. Despite the IPD clearly remaining a valuable tool during operative procedures, surgeons should recog-nize the limitations of IPDs and make comprehensive decisions about surgical treatments. |
| Keywords | spinal cord tumor intraoperative pathological diagnosis final pathological diagnosis concordance rate |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 455 |
| End Page | 460 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511612 |
| Web of Science KeyUT | 000697944600007 |
| NAID | 120007146040 |
| JaLCDOI | 10.18926/AMO/62396 |
|---|---|
| FullText URL | 75_4_447.pdf |
| Author | Kono, Reika| Hamasaki, Ichiro| Kishimoto, Fumiko| Ohtuski, Hiroshi| Shibata, Kiyo| Morizane, Yuki| Shiraga, Fumio| |
| Abstract | In high myopia, eye dislocation due to increased globe volume or tight orbital volume causes acquired esotro-pia. GOR (globe/orbit volume ratio), an indicator of the degree of progression of this pathology, was investi-gated the relationships among easily obtained clinical parameters. In this retrospective study, 20 eyes from 10 acquired esotropia patients with high myopia but without abduction limitations were examined. The mean age of the patients was 63.7 ± 8.2 years (mean ± standard deviation). Volumes were measured on the three-dimen-sional fast imaging employing steady-state acquisition magnetic resonance imaging images using the vol-ume-measurement function. Correlations between GOR and the displacement angle of the globe (DA), axial length (AL), and equatorial diameter (ED) were investigated. Mean DA, AL, ED, and GOR values were 107.5 ± 8.5°, 28.86 ± 1.92 mm, 25.00 ± 1.16 mm, and 0.36 ± 0.05, respectively. Only AL was correlated with GOR (p < 0.0001, R2 = 0.6649); DA (p = 0.30, R2 = 0.0633) and ED (p = 0.91, R2 = 0.0008) were not. AL was the only clinically available parameter to indicate globe/orbit volume imbalances in acquired esotropia with high myopia but without abduction limitation. AL may be important for the clinical assessment of the progression of this pathology. |
| Keywords | acquired esotropia high myopia (high myopes) globe volume magnetic resonance imaging limitation of abduction |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 447 |
| End Page | 453 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511611 |
| Web of Science KeyUT | 000697944600006 |
| NAID | 120007146039 |
| JaLCDOI | 10.18926/AMO/62395 |
|---|---|
| FullText URL | 75_4_439.pdf |
| Author | Mitsui, Takashi| Mishima, Sakurako| Tani, Kazumasa| Maki, Jota| Eto, Eriko| Hayata, Kei| Masuyama, Hisashi| |
| Abstract | Early diagnosis and therapy are important in a cesarean scar pregnancy (CSP), which can cause uterine rupture with resultant massive bleeding. However, there are some reports of CSPs continued to term. The optimal management of CSPs remains unclear; therefore, we investigated the clinical courses of CSPs diagnosed and treated at perinatal institutions in the Chugoku and Shikoku regions of Japan. We enrolled 60 women diag-nosed with CSP at 21 institutions from January 2006 to December 2015. Of the 60 women diagnosed with CSP, 57 were treated. Pregnancy was terminated in 48 women and continued in 9. Thirteen women underwent transabdominal hysterectomy; they experienced no postoperative complications or allogeneic blood transfu-sion. Nine women received therapies such as dilation and curettage, and 26 received non-surgical therapies such as methotrexate and topical administration of potassium chloride. Among 9 women who chose to con-tinue with their CSP, 7 successfully delivered newborns, 2 had uterine ruptures in the second trimester, and all women required transabdominal hysterectomy. Diagnosis and therapy in the first trimester of pregnancy are important in the management strategy of a CSP. When continuing a CSP, the risk of uterine rupture and trans-abdominal hysterectomy must be considered. |
| Keywords | cesarean scar pregnancy uterine rupture hysterectomy methotrexate potassium chloride |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 439 |
| End Page | 445 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511610 |
| Web of Science KeyUT | 000697944600005 |
| NAID | 120007146038 |
| JaLCDOI | 10.18926/AMO/62394 |
|---|---|
| FullText URL | 75_4_431.pdf |
| Author | Kunitomi, Toshiki| Nasu, Junichirou| Minami, Daisuke| Iwamoto, Takayuki| Nishie, Hiroyuki| Saito, Shinya| Fujiwara, Toshiyoshi| Matsuoka, Junji| |
| Abstract | This study aimed to evaluate whether there are differences in the attitudes and practices of cancer pain manage-ment between medical oncologists and palliative care physicians. An online nationwide survey was used to collect responses from board-certified medical oncologists and palliative care physicians in Japan. The survey questionnaire comprised 30 questions. The differences in responses between medical oncologists and palliative care physicians were examined. Out of the 1,227 questionnaires sent, 522 (42.5%) were returned. After apply-ing the exclusion criteria, 445 questionnaires (medical oncologists: n = 283; palliative care physicians: n = 162) were retained for analysis. Among the questions about potential barriers to optimal cancer pain man-agement, both medical oncologists and palliative care physicians considered the reluctance of patients to take opioids due to fear of adverse effects as the greatest barrier. Significantly different ratings between medical oncologists and palliative care physicians were observed on 5 of the 8 questions in this area. Significantly differ-ent ratings were observed for all questions concerning pain specialists and their knowledge. For effective cancer pain management, it is important to account for differences in attitudes and practice between medical oncolo-gists and palliative care physicians. |
| Keywords | cancer pain management opioid medical oncologist palliative care physician barriers |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 431 |
| End Page | 437 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511609 |
| Web of Science KeyUT | 000697944600004 |
| NAID | 120007146037 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ichikawa, Keishi| Miyoshi, Toru| Osawa, Kazuhiro| Miki, Takashi| Morimitsu, Yusuke| Akagi, Noriaki| Nakashima, Mitsutaka| Ito, Hiroshi| |
| Keywords | coronary computed tomography angiography non-alcoholic fatty liver disease perivascular coronary inflammation |
| Published Date | 2021-08-27 |
| Publication Title | Medicine |
| Volume | volume100 |
| Issue | issue34 |
| Publisher | Lippincott Williams & Wilkins |
| Start Page | e27043 |
| ISSN | 0025-7974 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 the Author(s). |
| File Version | publisher |
| PubMed ID | 34449489 |
| DOI | 10.1097/MD.0000000000027043 |
| Web of Science KeyUT | 000691370700047 |
| Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000027043 |
| FullText URL | fulltext20210908-3.pdf |
|---|---|
| Author | Hayakawa, Ichiro| Matsumaru, Naochika| Sakakura, Akira| |
| Note | This is an Accepted Manuscript of an article published by American Chemical Society | |
| Published Date | 2021-7-7 |
| Publication Title | The Journal of Organic Chemistry |
| Volume | volume86 |
| Issue | issue14 |
| Publisher | American Chemical Society (ACS) |
| Start Page | 9802 |
| End Page | 9810 |
| ISSN | 0022-3263 |
| NCID | AA00704100 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 34231354 |
| DOI | 10.1021/acs.joc.1c01193 |
| Web of Science KeyUT | 000674931400046 |
| Related Url | isVersionOf https://doi.org/10.1021/acs.joc.1c01193 |
| FullText URL | fulltext20210908-1.pdf figure20210908-1.pdf |
|---|---|
| Author | Namba, Takahiro| Tsuge, Mitsuru| Yashiro, Masato| Saito, Yukie| Liu, Keyue| Nishibori, Masahiro| Morishima, Tsuneo| Tsukahara, Hirokazu| |
| Keywords | Influenza Acute respiratory distress syndrome High mobility group box 1 Human pulmonary microvascular endothelial cell Cytokine Tumor necrosis factor-α |
| Note | This is an Accepted Manuscript of an article published by Springer Science. This fulltext is available in Aug. 2022.| |
| Published Date | 2021-8-29 |
| Publication Title | Inflammation Research |
| Publisher | Springer Science and Business Media LLC |
| ISSN | 1023-3830 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 34455489 |
| DOI | 10.1007/s00011-021-01496-5 |
| Web of Science KeyUT | 000690802000001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00011-021-01496-5 |
| FullText URL | fulltext20210908-1.pdf |
|---|---|
| Author | Hasegawa, Kosei| Tanaka, Hiroyuki| Futagawa, Natsuko| Miyahara, Hiroyuki| Higuchi, Yousuke| Tsukahara, Hirokazu| |
| Note | This is the peer reviewed version of the following article: [Hasegawa, K., Tanaka, H., Futagawa, N., Miyahara, H., Higuchi, Y., & Tsukahara, H. (2021). A novel pathogenic variant p.Asp797Val in IFIH1 in a Japanese boy with overlapping Singleton-Merten syndrome and Aicardi-Goutières syndrome. American Journal of Medical Genetics Part A, 188A: 249– 252. ], which has been published in final form at [https://doi.org/10.1002/ajmg.a.62478]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| Published Date | 2021-8-28 |
| Publication Title | American Journal of Medical Genetics Part A |
| Volume | volume188A |
| Publisher | Wiley |
| Start Page | 249 |
| End Page | 252 |
| ISSN | 1552-4825 |
| NCID | AA11815067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Wiley Periodicals LLC. |
| File Version | author |
| PubMed ID | 34453469 |
| DOI | 10.1002/ajmg.a.62478 |
| Web of Science KeyUT | 000690679100001 |
| Related Url | isVersionOf https://doi.org/10.1002/ajmg.a.62478 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamamoto, Norio| Sukegawa, Shintaro| Yamashita, Kazutaka| Manabe, Masaki| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Ozaki, Toshifumi| Kawasaki, Keisuke| Nagatsuka, Hitoshi| Furuki, Yoshihiko| Yorifuji, Takashi| |
| Keywords | patient variables osteoporosis deep learning convolutional neural network ensemble model effect size |
| Published Date | 2021-08-20 |
| Publication Title | Medicina-Lithuania |
| Volume | volume57 |
| Issue | issue8 |
| Publisher | MDPI |
| Start Page | 846 |
| ISSN | 1010-660X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34441052 |
| DOI | 10.3390/medicina57080846 |
| Web of Science KeyUT | 000689547600001 |
| Related Url | isVersionOf https://doi.org/10.3390/medicina57080846 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Obata, Kyoichi| Okui, Tatsuo| Ono, Sawako| Umemori, Koki| Ryumon, Shoji| Ono, Kisho| Yao, Mayumi| Yoshioka, Norie| Ibaragi, Soichiro| Sasaki, Akira| |
| Keywords | methotrexate lymphoproliferative disorders Epstein-Barr virus mucocutaneous ulcer rheumatoid arthritis |
| Published Date | 2021-07-30 |
| Publication Title | Diagnostics |
| Volume | volume11 |
| Issue | issue8 |
| Publisher | MDPI |
| Start Page | 1375 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34441310 |
| DOI | 10.3390/diagnostics11081375 |
| Web of Science KeyUT | 000688919100001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics11081375 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Akezaki, Yoshiteru| Nakata, Eiji| Kikuuchi, Masato| Tominaga, Ritsuko| Kurokawa, Hideaki| Okamoto, Masaki| Hamada, Makiko| Aogi, Kenjiro| Ohsumi, Shozo| Sugihara, Shinsuke| |
| Keywords | breast cancer leisure surgery rehabilitation factor |
| Published Date | 2021-08-22 |
| Publication Title | Healthcare |
| Volume | volume9 |
| Issue | issue8 |
| Publisher | MDPI |
| Start Page | 1078 |
| ISSN | 2227-9032 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34442215 |
| DOI | 10.3390/healthcare9081078 |
| Web of Science KeyUT | 000690566600001 |
| Related Url | isVersionOf https://doi.org/10.3390/healthcare9081078 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nokihara, Kanoko| Okada, Yoshihiro| Ohata, Shinichiro| Monden, Yuki| |
| Keywords | transcriptome RNA-seq sweetpotato weevil resistance juvenile hormones terpenes |
| Published Date | 2021-07-27 |
| Publication Title | Plants-Basel |
| Volume | volume10 |
| Issue | issue8 |
| Publisher | MDPI |
| Start Page | 1535 |
| ISSN | 2223-7747 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34451581 |
| DOI | 10.3390/plants10081535 |
| Web of Science KeyUT | 000689767700001 |
| Related Url | isVersionOf https://doi.org/10.3390/plants10081535 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hutami, Islamy Rahma| Izawa, Takashi| Khurel-Ochir, Tsendsuren| Sakamaki, Takuma| Iwasa, Akihiko| Tanaka, Eiji| |
| Keywords | HIF1 M1/M2 macrophage S1P wound healing |
| Published Date | 2021-08-20 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume22 |
| Issue | issue16 |
| Publisher | MDPI |
| Start Page | 8992 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34445695 |
| DOI | 10.3390/ijms22168992 |
| Web of Science KeyUT | 000689169900001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms22168992 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Asanuma, Masato| Miyazaki, Ikuko| |
| Keywords | glutathione neuroprotection parkinsonism astrocyte region specificity striatum mesencephalon oxidative stress Nrf2 metallothionein serotonin 5-HT1A receptor |
| Published Date | 2021-08-13 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume22 |
| Issue | issue16 |
| Publisher | MDPI |
| Start Page | 8689 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34445395 |
| DOI | 10.3390/ijms22168689 |
| Web of Science KeyUT | 000690633200001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms22168689 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamaguchi, Daisuke| Hanaki, Tatsuya| Ishino, Yuji| Takasaki, Masaya| Mizuno, Takeshi| |
| Keywords | soft robotics pneumatic actuator film molding welding polyimide filmotics |
| Published Date | 2021-07-30 |
| Publication Title | Actuators |
| Volume | volume10 |
| Issue | issue8 |
| Publisher | MDPI |
| Start Page | 177 |
| ISSN | 2076-0825 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| DOI | 10.3390/act10080177 |
| Web of Science KeyUT | 000688613100001 |
| Related Url | isVersionOf https://doi.org/10.3390/act10080177 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nguyen Sao, Mai| Dao Duy, Hanh| Nakashima, Mai| Kumamoto, Kotaro| Nguyen Thi Thu, Thuy| Kobata, Tohru| Saitoh, Kuniyuki| Hirai, Yoshihiko| |
| Keywords | QTL salt tolerance grain yield yield components reproductive stage |
| Published Date | 2021-08-15 |
| Publication Title | Agriculture |
| Volume | volume11 |
| Issue | issue8 |
| Publisher | MDPI |
| Start Page | 777 |
| ISSN | 2077-0472 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| DOI | 10.3390/agriculture11080777 |
| Web of Science KeyUT | 000688690100001 |
| Related Url | isVersionOf https://doi.org/10.3390/agriculture11080777 |
| Title Alternative | Annual report / Institute of Plant Science and Resources, Okayama University |
|---|---|
| FullText URL | IPSR_28.pdf |
| Author | Institute of Plant Science and Resources, Okayama University| |
| Publication Title | Annual Report, Institute of Plant Science and Resources Okayama University |
| Published Date | 2021-03-31 |
| Volume | volume28 |
| Start Page | 1 |
| End Page | 62 |
| ISSN | 2186-4918 |
| language | Japanese |
| File Version | publisher |
| JaLCDOI | 10.18926/AMO/62380 |
|---|---|
| FullText URL | 75_4_423.pdf |
| Author | Takihira, Shota| Furumatsu, Takayuki| Okazaki, Yuki| Hiranaka, Takaaki| Kintaka, Keisuke| Kodama, Yuya| Kamatsuki, Yusuke| Miyazawa, Shinichi| Ozaki, Toshifumi | |
| Abstract | The treatment of medial meniscus posterior root tears (MMPRTs) has evolved to include a variety of repair strategies. This study investigated the location of the articular cartilage degeneration during second-look arthroscopy after transtibial pullout repair with a modified Mason-Allen suture using FasT-Fix (F-MMA) in 22 patients with MMPRTs. Second-look arthroscopy was performed approximately 1 year postoperatively to eval-uate the healing status of the medial meniscus (MM). Articular cartilage degeneration was assessed using the International Cartilage Repair Society grade at primary surgery and again at second-look arthroscopy. Articular surfaces of the medial/lateral femoral condyles, the medial/lateral tibial plateaus, the patella and the trochlea were divided into several subcompartments (MF 1-9, LF 1-9, MT 1-5, LT 1-5, P 1-9, T 1-3). Clinical evaluations used the Japanese Knee Injury and Osteoarthritis Outcome, Lysholm, and International Knee Documentation Committee scores. Second-look arthroscopic findings showed complete healing of the MM posterior root in all patients. Significant differences between pullout repair and second-look arthroscopy were observed for MF 2 and 4, LF 7, and P 7. All clinical outcomes were improved. Our results indicate that this technique improves clinical outcomes postoperatively and may prevent the progression of cartilage degenera-tion on the loading surface of the medial knee compartment. |
| Keywords | articular cartilage medial meniscus modified Mason-Allen suture technique posterior root tear second-look arthroscopy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 423 |
| End Page | 430 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511608 |
| Web of Science KeyUT | 000697944600003 |
| NAID | 120007146061 |
| JaLCDOI | 10.18926/AMO/62379 |
|---|---|
| FullText URL | 75_4_415.pdf |
| Author | Sun, Jingkai| Lin, Wenfeng| Wang, Qixu| Sakai, Akiko| Xue, Ruizhi| Watanabe, Masami| Liu, Chunxiao| Sadahira, Takuya| Nasu, Yasutomo| Xu, Abai| Huang, Peng| |
| Abstract | Human RAD17, as an agonist of checkpoint signaling, plays an essential role in mediating DNA damage. This hospital-based case-control study aimed to explore the association between RAD17 rs1045051, a missense sin-gle nucleotide polymorphism (SNP), and prostate cancer risk. Subjects were 358 prostate cancer patients and 314 cancer-free urology patients undergoing treatment at the Zhujiang Hospital of Southern Medical University in China. RAD17 gene polymorphism rs1045051 was evaluated by the SNaPshot method. Compared with the RAD17 gene polymorphism rs1045051 AA genotype, there was a higher risk of prostate cancer for the CC gen-otype (adjusted odds ratio [AOR] = 1.731, 95% confidence interval [95%CI] = 1.031−2.908, p = 0.038). Compared with the A allele, the C allele was significantly associated with the disease status (AOR = 1.302, 95%CI = 1.037−1.634, p = 0.023). All these findings indicate that in the SNP rs1045051, both the CC genotype and C allele may have a substantial influence on the prostate cancer risk. |
| Keywords | prostate cancer single-nucleotide polymorphisms cell cycle checkpoint rs1045051 RAD17 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 415 |
| End Page | 421 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511607 |
| Web of Science KeyUT | 000697944600002 |
| NAID | 120007146060 |
