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Akisada, Naoki Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Monden, Nobuya Department of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center
Kishino, Takehito Department of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center
Aoi, Jiro Department of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center
Hayashi, Yuji Department of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center
Takahashi, Saori Department of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center
Nakamura, Masataka Department of Head and Neck Surgery, National Hospital Organization Shikoku Cancer Center
Ishihara, Hisashi Department of Otolaryngology, Japanese Red Cross Okayama Hospital
Nishizaki, Kazunori Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Abstract
Background: It is well known that chemotherapy for adolescent and young adult (AYA) patients with cancer can reduce fertility regardless of the regimen. A decline in fertility greatly affects the quality of life of cancer survivors in the AYA age group; however, few patients are thought to be receiving fertility preservation measures.
Methods: A questionnaire survey was conducted to assess the current understanding and consideration of fertility among otorhinolaryngologists/head and neck surgeons who treat AYA patients with cancer, and to inform them of the guidelines for fertility preservation. A total of 275 otorhinolaryngologists/head and neck surgeons working at our hospital in Ehime, Japan, six neighboring universities, and their affiliated facilities were included in this study. The questionnaire was mailed and requested to be returned by fax. Twenty questions were asked about respondents’ years of experience as physicians, specialties, experience in medical care and chemotherapy for AYA patients with cancer, and knowledge and experience in fertility reduction measures.
Results: Although 58.7% of the physicians were aware that cryopreservation of eggs and sperm prior to chemotherapy was recommended, only 7 out of 40 physicians (17.5%) had referred AYA patients with cancer to an appropriate medical facility (department) after obtaining informed consent for chemotherapy.
Conclusions: Although fertility preservation has been discussed at professional conferences and seminars, consideration and actions in the field of otorhinolaryngology/head and neck surgery have not been sufficient. We hope that the results of this survey will help raise awareness of fertility preservation.
Keywords
fertility preservation
otorhinolaryngology
head and neck cancer
adolescent and young adult generation
guidelines
Japan
Note
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s10147-021-01905-z
Published Date
2021-5-6
Publication Title
International Journal of Clinical Oncology
Volume
volume26
Publisher
Springer Science and Business Media LLC
Start Page
1196
End Page
1202
ISSN
1341-9625
Content Type
Journal Article
language
English
OAI-PMH Set
岡山大学
Copyright Holders
© Japan Society of Clinical Oncology 2021
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isVersionOf https://doi.org/10.1007/s10147-021-01905-z