| ID | 66640 |
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Iwamuro, Masaya
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
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Takenaka, Ryuta
Department of Internal Medicine, Tsuyama Chuo Hospital
Toyokawa, Tatsuya
Department of Gastroenterology, National Hospital Organization Fukuyama Medical Center
Kita, Masahide
Department of Internal Medicine, Okayama City Hospital
Tsuzuki, Takao
Department of Internal Medicine, Japanese Red Cross Society Himeji Hospital
Yoshioka, Masao
Department of Internal Medicine, Okayama Saiseikai General Hospital
Gotoda, Tatsuhiro
Department of Gastroenterology and Hepatology, Kurashiki Central Hospital
Okanoue, Shotaro
Department of Gastroenterology, Mitoyo General Hospital
Matsubara, Minoru
Department of Gastroenterology, Sumitomo Besshi Hospital
Sakaguchi, Chihiro
Department of Endoscopy, National Hospital Organization Shikoku Cancer Center
Otsuka, Motoyuki
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
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| Abstract | Gastric emphysema is characterized by the presence of intramural gas in the stomach without bacterial infection. Due to its rarity, most reports on gastric emphysema have been limited to single-case studies, and this condition's clinical and endoscopic features have not been thoroughly investigated. In this study, we analyzed 45 patients with gastric emphysema from 10 institutions and examined their characteristics, endoscopic features, and outcomes. The mean age at diagnosis of gastric emphysema in our study population (35 males and 10 females) was 68.6 years (range, 14-95 years). The top five underlying conditions associated with gastric emphysema were the placement of a nasogastric tube (26.7%), diabetes mellitus (20.0%), post-percutaneous endoscopic gastrostomy (17.8%), malignant neoplasms (17.8%), and renal failure (15.6%). Among the 45 patients, 42 were managed conservatively with fasting and administration of proton pump inhibitors. Unfortunately, seven patients died within 30 days of diagnosis, and 35 patients experienced favorable recoveries. The resolution of gastric emphysema was confirmed in 30 patients through computed tomography (CT) scans, with a mean duration of 17.1 +/- 34.9 days (mean +/- standard deviation [SD], range: 1-180 days) from the time of diagnosis to the disappearance of the gastric intramural gas. There were no instances of recurrence. Endoscopic evaluation was possible in 18 patients and revealed that gastric emphysema presented with features such as redness, erosion, coarse mucosa, and ulcers, with fewer mucosal injuries on the anterior wall (72.2%), a clear demarcation between areas of mucosal injury and intact mucosa (61.1%), and predominantly longitudinal mucosal injuries on the stomach folds (50.0%). This study is the first English-language report to analyze endoscopic findings in patients with gastric emphysema.
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| Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-52633-z
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| Published Date | 2024-01-25
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| Publication Title |
Scientific Reports
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| Volume | volume14
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| Issue | issue1
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| Publisher | Nature Portfolio
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| Start Page | 2202
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| ISSN | 2045-2322
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| Content Type |
Journal Article
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| language |
English
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| OAI-PMH Set |
岡山大学
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| Copyright Holders | © The Author(s) 2024
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| File Version | publisher
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| Related Url | isVersionOf https://doi.org/10.1038/s41598-024-52633-z
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| License | http://creativecommons.org/licenses/by/4.0/
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| Citation | Iwamuro, M., Takenaka, R., Toyokawa, T. et al. Endoscopic and clinical features of gastric emphysema. Sci Rep 14, 2202 (2024). https://doi.org/10.1038/s41598-024-52633-z
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