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JaLCDOI 10.18926/19770
Title Alternative Etiology and pathogenesis of chronic pancreatitis
FullText URL 059_068_082.pdf
Author Harada, Hideo| Matsumoto, Shuji| Ochi, Koji| Takeda, Masahiko| Senou, Toshinobu| Irie, Seiji| Tanaka, Juntaro|
Abstract 慢性膵炎の成因の主たるものは,アルコール性,特発性,胆石性である。病態面では,社会的・家庭的にもっとも責任が重い壮年期に頑固な疼痛,消化吸収障害,二次性糖尿病のために生活の質が低下することが問題になる。経過中に併発してくる膵およびそのほかの臓器の癌,および糖尿病の合併症による死亡も少なくない。アルコール性慢性膵炎の初期病変の発生機序としては,①膵過分泌の結果として細膵管内に形成される蛋白栓による膵液流出障害と,②蛋白栓あるいはアルコールの直接障害作用による細膵管上皮の損傷,およびその結果生じる膵管狭窄による膵液流出障害が注目されている。膵液流出障害はその上流域に実質細胞の破壊と間質の線維化をおこす。膵液には多くの生化学的異常が認められ,いったん発生した膵管の構造異常とあいまって慢性膵炎進展の原因となる。素因および栄養のアンバランスは発症,進展の促進因子となる。発症を予防し,進展を阻止する手段を開発するためには素因および飲酒・食事を含む環境因子の解析が今後の重要な課題である。
Keywords 慢性膵炎 (Chronic pancreatitis) 成因 (Etiology) 発生機序 (Pathogenesis)
Publication Title 環境病態研報告
Published Date 1988-08
Volume volume59
Start Page 68
End Page 82
ISSN 0913-3771
language Japanese
File Version publisher
NAID 120002308982
JaLCDOI 10.18926/19727
Title Alternative Clinical effects of serial artificial CO(2) baths on degenerative disorders in consideration of the improved tissue perfusion.
FullText URL 058_022_030.pdf
Author Komoto, Yoshiaki| Kohmoto, Tomoji| Sunakawa, Mitsuru| Yagi, Nobuko| Yorozu, Hidenori| Matsumoto, Yasunobu|
Abstract 組織循環の良不良は,結合織の退行性病変の予後に大いに影響をおよぼすものである。人工炭酸泉を用いた実験的検討で,すでに組織循環の30 % 増加を認めており,臨床的治験により好傾向を示す結果を得つつある。結合織病変を主とする慢性疾患4症例の治験前後に局所組織流量を測定して評価することができた。局所組織流量は医用質量分析装置を介したオンラインシステムで測定計算した。人工炭酸浴は,炭酸ガスキャビン,および人工炭酸浴剤浴を用いた。人工炭酸泉浴は,1カ月より1年におよび,それぞれ自覚症状の著名な改善と,組織流量の増加を定量しえた。人工炭酸泉の連浴による組織流量の改善は、結合織の退行性病変に有効に作用するものである。
Publication Title 環境病態研報告
Published Date 1987-08
Volume volume58
Start Page 22
End Page 30
ISSN 09133771
language Japanese
File Version publisher
NAID 120002309112
JaLCDOI 10.18926/19592
FullText URL Mem_Fac_Eng_OU_31_2_29.pdf
Author Oka, Hisao| Ohshima, Masakazu|
Abstract Knee replacement arthroplasty is indicated for the patient with advanced knee pain, knee deformation, and knee functional disorder. The aim of this study was to estimate loosening after a knee replacement arthroplasty. Loosening is measured by a frequency response function, and mobility by random vibration. The modal parameters for the knee joint are obtained by applying a modal analysis to the frequency response function. The values decrease as the knee joint prosthesis loosened. These parameters serve as an index for the condition between a thighbone and the prosthesis. The various indexes will greatly clarify the stage of advance in the loosening of knee-joint prostheses.
Publication Title Memoirs of the Faculty of Engineering, Okayama University
Published Date 1997-03-28
Volume volume31
Issue issue2
Start Page 29
End Page 37
ISSN 0475-0071
language English
File Version publisher
NAID 120002309172
JaLCDOI 10.18926/19583
Title Alternative BALNEOLOGICAL STUDIES USING RADIO-ACTIVE ISOTOPES (1) ON THE MECHANISM OF THE ACTION OF SODIUM SULFATE SPRING BATH.
FullText URL 007_001_005.pdf
Author Oshima, Yoshio| Yokota, Takeo|
Abstract Using Na(2)SO(4) labelled with S(35) transition of sulfate ion into the body across the skin was investigated soon after the bath in sodium sulfate solution at varying conditions. Mice were used as test animal. Percutaneous absorption of sulfate ion proved to be promoted at high bath temperature (45℃) than at indifferent temperature(37℃). stronger by the bath of longer duration (30min.) than by the bath of shorter duration (10min.), increased after repeated baths than after a single bath. It was accelerated by making a burn to the skin of the bathed animals. Layton and Dziewiatkowski proved that the parenterally administered sulfate ion was partly fixed in the connective tissue as chondroitin sulfate. The author had proved that chondroitin sulfate relieves pain, increases peripheral circulation and when administered parenterally promotes production of immune bodies. In Japan natural and artificial Glauber's salt spring bath are known to have a beneficial effect on wound healing, but no satisfactory explanation was given till today. Lith reported that a hypertonic solution of sodium sulfate promoten wound cure by external application and Seki showed that subcutaneous connective tissue of mice was stimulated by the bath in sodium sulfate spring. And so the abovementioned author's data seem to throw some light on solving the problem.
Publication Title 岡山大学温泉研究所報告
Published Date 1952-08
Volume volume7
Start Page 1
End Page 5
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002309061
Author Ling, Nay Kay|
Published Date 1959-04-25
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue5-2
Content Type Journal Article
Author Tottori, Yukio|
Published Date 1959-03-15
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue3-2
Content Type Journal Article
Author Watanabe, Takashi|
Published Date 1958-07-31
Publication Title 岡山医学会雑誌
Volume volume70
Issue issue7
Content Type Journal Article
Author Watanabe, Takashi|
Published Date 1958-07-31
Publication Title 岡山医学会雑誌
Volume volume70
Issue issue7
Content Type Journal Article
Author Marukawa, Shoichi|
Published Date 1961-09-30
Publication Title 岡山医学会雑誌
Volume volume73
Issue issue7-9
Content Type Journal Article
Author Marukawa, Shoichi|
Published Date 1961-09-30
Publication Title 岡山医学会雑誌
Volume volume73
Issue issue7-9
Content Type Journal Article
Author Seito, Ichiro|
Published Date 1961-03-30
Publication Title 岡山医学会雑誌
Volume volume73
Issue issue1-3
Content Type Journal Article
Author Shiaku, Takeru| Ogino, Keichiro| Aono, Kaname| Hada, Yoshihiro|
Published Date 1963-09-30
Publication Title 岡山医学会雑誌
Volume volume75
Issue issue7-9
Content Type Journal Article
Author Matsuura, Umeharu| Yasuhara, Goro| Sato, Minoru|
Published Date 1963-06-30
Publication Title 岡山医学会雑誌
Volume volume75
Issue issue4-6
Content Type Journal Article
Author Tanaka, Takashi|
Published Date 1959-12-30
Publication Title 岡山医学会雑誌
Volume volume72
Issue issue1
Content Type Journal Article
Author Shimada, Yoshihiro| Kobayashi, Toshinari| Kojima, Sumi-ichi| Miyashita, Tomoyoshi| Kinochita, Akio| Tanetani, Setsuro| Takayama, Tadasuke| Tamao, Hiroyasu|
Published Date 1965-07-30
Publication Title 岡山医学会雑誌
Volume volume77
Issue issue7
Content Type Journal Article
Author Ueda, Toshihiko| Mii, Takashi| Kawai, Kiyoshi|
Published Date 1968-10-30
Publication Title 岡山医学会雑誌
Volume volume80
Issue issue9-10
Content Type Journal Article
Author Hiraba, Koichi|
Published Date 1968-10-30
Publication Title 岡山医学会雑誌
Volume volume80
Issue issue9-10
Content Type Journal Article
Author Takaki, Shin| Hirota, Shigeru|
Published Date 1968-04-30
Publication Title 岡山医学会雑誌
Volume volume80
Issue issue3-4
Content Type Journal Article
Author Okuda, Rikuo|
Published Date 1967-06-30
Publication Title 岡山医学会雑誌
Volume volume79
Issue issue5-6
Content Type Journal Article
Author Mori, Toshio|
Published Date 1970-12-30
Publication Title 岡山医学会雑誌
Volume volume82
Issue issue11-12
Content Type Journal Article