result 774 件
| FullText URL | fulltext_.pdf |
|---|---|
| Author | Matsumoto, Jun| San, Su Nwe| Fujiyoshi, Masachika| Kawauchi, Ayano| Chiba, Natsumi| Tagai, Ran| Sanbe, Ryoko| Yanaka, Shiho| Sakaue, Hiroaki| Kato, Yoshinori| Nakamura, Hiroyoshi| Yamada, Harumi| Ariyoshi, Noritaka| |
| Keywords | Genetic markers Haplotypes |
| Published Date | 2019-10-23 |
| Publication Title | Journal of Human Genetics |
| Volume | volume65 |
| Publisher | Japan Society of Human Genetics |
| Start Page | 143 |
| End Page | 153 |
| ISSN | 1434-5161 |
| NCID | AA11206160 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31645655 |
| DOI | 10.1038/s10038-019-0685-2 |
| Web of Science KeyUT | 000513167200007 |
| Related Url | isVersionOf https://doi.org/10.1038/s10038-019-0685-2 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Uchida, Daisuke| Kato, Hironari| Matsumoto, Kazuyuki| Ishihara, Yuki| Matsumi, Akihiro| Saragai, Yosuke| Takada, Saimon| Yabe, Shuntaro| Muro, Shinichiro| Tomoda, Takeshi| Horiguchi, Shigeru| Okada, Hiroyuki| |
| Keywords | Endoscopic ultrasound Diagnostic screening program Pancreatic diseases Biliary tract diseases |
| Published Date | 2019-12-18 |
| Publication Title | BMC Gastroenterology |
| Volume | volume19 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 220 |
| ISSN | 1471-230X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2019 |
| File Version | publisher |
| PubMed ID | 31852458 |
| DOI | 10.1186/s12876-019-1141-7 |
| Web of Science KeyUT | 000510482800002 |
| Related Url | isVersionOf https://doi.org/10.1186/s12876-019-1141-7 |
| JaLCDOI | 10.18926/AMO/57951 |
|---|---|
| FullText URL | 74_1_41.pdf |
| Author | Amano, Hoichi| Fujimoto, Kenichi| Fujimori, Makoto| Saka, Natsumi| Nomura, Kyoko| Tanihara, Shinichi| |
| Abstract | We aimed to clarify the prevalence of polypharmacy among elderly individuals in Japan. We used the data obtained from a large-scale population-based representative database of health insurance claims in a single prefecture in Japan. We examined all of the outpatient and pharmaceutical health insurance claims for National Health Insurance and those for Late-stage Elderly Health Insurance in Nagasaki Prefecture, Japan between April and June 2016. When two or more claim forms were issued for a patient in a single month, we combined the data and identified the number of prescribed drugs for each person. The definition of polypharmacy is a the prescription of six or more drugs per month. We investigated the prevalence of polypharmacy among the beneficiaries of the two insurance systems. Of the 605,406 beneficiaries of the 2 insurance systems, 121,033 (20.0%) patients with polypharmacy were identified. The prevalence of polypharmacy increased with age, especially among the beneficiaries aged > 85 years, with about half of the beneficiaries having polypharmacy status. About half of the people aged > 85 years in the database had polypharmacy status. When a drug is prescribed to an elderly individual, it is necessary to consider the possibility of polypharmacy-related problems. |
| Keywords | health insurance claims late-stage elderly health insurance national health insurance Japan polypharmacy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-02 |
| Volume | volume74 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 41 |
| End Page | 48 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32099247 |
| Web of Science KeyUT | 000516606200006 |
| NAID | 120006795618 |
| JaLCDOI | 10.18926/AMO/57946 |
|---|---|
| FullText URL | 74_1_1.pdf |
| Author | Chen, Yuehua| Ohara, Toshiaki| Xing, Boyi| Qi, Jiping| Noma, Kazuhiro| Matsukawa, Akihiro| |
| Abstract | Iron is a trace but vital element in the human body and is necessary for a multitude of crucial processes in life. However, iron overload is known to induce carcinogenesis via oxidative stress. Cancer cells require large amounts of iron for their rapid division and cell growth. Iron was recently found to play a role in cancer stem cells (CSCs); it maintains stemness during development. Iron also plays an important role in stemness by moderating reactive oxygen species. Thus, iron metabolism in CSCs is a promising therapeutic target. In this review, we summarize the roles of iron in cancer cells and CSCs. We also summarize anti-cancer therapeutic studies with iron chelators and describe our expectation of a new therapeutic strategy for CSCs on the basis of our findings. |
| Keywords | cancer stem cell stemness iron chelation chemotherapy |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-02 |
| Volume | volume74 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 1 |
| End Page | 6 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32099242 |
| Web of Science KeyUT | 000516606200001 |
| NAID | 120006795613 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ozuru, Ryo| Wakao, Shohei| Tsuji, Takahiro| Ohara, Naoya| Matsuba, Takashi| Amuran, Muhammad Y.| Isobe, Junko| Iino, Morio| Nishida, Naoki| Matsumoto, Sari| Iwadate, Kimiharu| Konishi, Noriko| Yasuda, Kaori| Tashiro, Kosuke| Hida, Misato| Yadoiwa, Arisato| Kato, Shinsuke| Yamashita, Eijiro| Matsumoto, Sohkichi| Kurozawa, Yoichi| Dezawa, Mari| Fujii, Jun| |
| Keywords | Muse cells Shiga toxin-producing Escherichia coli acute encephalopathy |
| Published Date | 2020-01-08 |
| Publication Title | Molecular Therapy |
| Volume | volume28 |
| Issue | issue1 |
| Publisher | Elsevier |
| Start Page | 100 |
| End Page | 118 |
| ISSN | 15250016 |
| NCID | AA11475060 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 The Author(s). |
| File Version | publisher |
| PubMed ID | 31607541 |
| DOI | 10.1016/j.ymthe.2019.09.023 |
| Web of Science KeyUT | 000506204400011 |
| Related Url | isVersionOf https://doi.org/10.1016/j.ymthe.2019.09.023 |
| FullText URL | JCR25_4_45.pdf Fig.pdf |
|---|---|
| Author | Motokura, Yumi| Watanabe, Haruki| Yamamura, Yuriko| Kano, Yuzuki| Matsumoto, Yoshinori| Kawabata, Tomoko| Sada, Ken-ei| Wada, Jun| |
| Published Date | 2019-06 |
| Publication Title | Journal of Clinical Rheumatology |
| Volume | volume25 |
| Issue | issue4 |
| Publisher | Lippincott, Williams & Wilkins |
| Start Page | 45 |
| End Page | 47 |
| ISSN | 1076-1608 |
| NCID | AA11016642 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 29470260 |
| DOI | 10.1097/RHU.0000000000000723 |
| Web of Science KeyUT | 000470908400007 |
| Related Url | isVersionOf https://doi.org/10.1097/RHU.0000000000000723 |
| FullText URL | SR9_1_8041.pdf |
|---|---|
| Author | Yoshioka, Yohsuke| Yamachika, Eiki| Nakanishi, Makoto| Ninomiya, Tadashi| Akashi, Sho| Kondo, Sei| Moritani, Norifumi| Kobayashi, Yasuhiro| Fujii, Tatsuo| Iida, Seiji| |
| Published Date | 2019-5-29 |
| Publication Title | Scientific Reports |
| Volume | volume9 |
| Publisher | Nature Publishing Group |
| Start Page | 8041 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2019 |
| File Version | publisher |
| PubMed ID | 31142769 |
| DOI | 10.1038/s41598-019-44389-8 |
| Web of Science KeyUT | 000469319300003 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-019-44389-8 |
| FullText URL | SR9_1_3054.pdf |
|---|---|
| Author | Hiramatsu, Sumie| Watanabe, Katsue S.| Zeggar, Sonia| Asano, Yosuke| Miyawaki, Yoshia| Yamamura, Yuriko| Katsuyama, Eri| Katsuyama, Takayuki| Watanabe, Haruki| Takano-Narazaki, Mariko| Matsumoto, Yoshinori| Kawabata, Tomoko| Sada, Ken-Ei| Wada, Jun| |
| Published Date | 2019-2-28 |
| Publication Title | Scientific Reports |
| Volume | volume9 |
| Publisher | Nature Publishing Group |
| Start Page | 3054 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2019 |
| File Version | publisher |
| PubMed ID | 30816218 |
| DOI | 10.1038/s41598-019-38809-y |
| Web of Science KeyUT | 000459891700064 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-019-38809-y |
| FullText URL | SR9_1_5817.pdf |
|---|---|
| Author | Ueno, Hiroshi| Suemitsu, Shunsuke| Murakami, Shinji| Kitamura, Naoya| Wani, Kenta| Matsumoto, Yosuke| Okamoto, Motoi| Ishihara, Takeshi| |
| Published Date | 2019-4-9 |
| Publication Title | Scientific Reports |
| Volume | volume9 |
| Publisher | Nature Publishing Group |
| Start Page | 5817 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2019 |
| File Version | publisher |
| PubMed ID | 30967573 |
| DOI | 10.1038/s41598-019-42290-y |
| Web of Science KeyUT | 000463869800019 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-019-42290-y |
| Author | Matsumoto, Kento| Hara, Sunao| Abe, Masanobu| |
|---|---|
| Published Date | 2019-11 |
| Publication Title | Proceedings of APSIPA Annual Summit and Conference |
| Volume | volume2019 |
| Content Type | Conference Paper |
| FullText URL | NCN7_3_146.pdf Fig.pdf |
|---|---|
| Author | Matsumoto, Namiko| Sato, Kota| Takahashi, Yoshiaki| Kawahara, Yuko| Yunoki, Taijun| Shang, Jingwei| Takemoto, Mami| Hishikawa, Nozomi| Ohta, Yasuyuki| Yamashita, Toru| Sakamoto, Maiko| Kondou, Eisei| Shibata, Rei| Yoshino, Tadashi| Ozaki, Toshifumi| Abe, Koji| |
| Keywords | neurolymphomatosis neuro-oncology peripheral neuropathy peripheral nerve rheumatoid arthritis T-cell lymphoma |
| Note | This fulltext will be available in Feb 2020| |
| Published Date | 2019-02-19 |
| Publication Title | Neurology and Clinical Neuroscience |
| Volume | volume7 |
| Issue | issue3 |
| Publisher | Wiley |
| Start Page | 146 |
| End Page | 149 |
| ISSN | 2049-4173 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1111/ncn3.12280 |
| Web of Science KeyUT | 000466785700011 |
| Related Url | isVersionOf https://doi.org/10.1111/ncn3.12280 |
| FullText URL | NCN7_3_132.pdf fig.pdf |
|---|---|
| Author | Takahashi, Yoshiaki| Sato, Kota| Matsumoto, Namiko| Kawahara, Yuko| Yunoki, Taijun| Shang, Jingwei| Takemoto, Mami| Hishikawa, Nozomi| Ohta, Yasuyuki| Yamashita, Toru| Abe, Koji| |
| Keywords | combination therapy contrast-enhanced magnetic resonance imaging frequent ischemic stroke giant cell arteritis temporal artery biopsy |
| Published Date | 2018-12-28 |
| Publication Title | Neurology and Clinical Neuroscience |
| Volume | volume7 |
| Issue | issue3 |
| Publisher | Wiley |
| Start Page | 132 |
| End Page | 135 |
| ISSN | 2049-4173 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1111/ncn3.12266 |
| Web of Science KeyUT | 000466785700007 |
| Related Url | isVersionOf https://doi.org/10.1111/ncn3.12266 |
| FullText URL | JAD71_1_327.pdf |
|---|---|
| Author | Feng, Tian| Yamashita, Toru| Shang, Jingwei| Shi, Xiaowen| Nakano, Yumiko| Morihara, Ryuta| Tsunoda, Keiichiro| Nomura, Emi| Sasaki, Ryo| Tadokoro, Koh| Matsumoto, Namiko| Hishikawa, Nozomi| Ohta, Yasuyuki| Abe, Koji| |
| Keywords | Alzheimer’s disease chronic cerebral hypoperfusion edaravone neural oxidative stress neuroinflammation neuronal loss |
| Note | The final publication is available at IOS Press through https://doi.org/10.3233/JAD-190369| |
| Published Date | 2019-09-03 |
| Publication Title | Journal of Alzheimer's Disease |
| Volume | volume71 |
| Issue | issue1 |
| Publisher | IOS Press |
| Start Page | 327 |
| End Page | 339 |
| ISSN | 1387-2877 |
| NCID | AA11545428 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31403949 |
| DOI | 10.3233/JAD-190369 |
| Web of Science KeyUT | 000484216500026 |
| Related Url | isVersionOf https://doi.org/10.3233/JAD-190369 |
| FullText URL | JBMRA_107_5_1021.pdf |
|---|---|
| Author | Kunitomi, Yosuke| Hara, Emilio Satoshi| Okada, Masahiro| Nagaoka, Noriyuki| Kuboki, Takuo| Nakano, Takayoshi| Kamioka, Hiroshi| Matsumoto, Takuya| |
| Keywords | apatite bioinspired mineralization bone hydrogel matrix vesicle nanofragments |
| Published Date | 2019-01-24 |
| Publication Title | Journal of Biomedical Materials Research Part A |
| Volume | volume107 |
| Issue | issue5 |
| Publisher | Wiley |
| Start Page | 1021 |
| End Page | 1030 |
| ISSN | 1549-3296 |
| NCID | AA11881516 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 The Authors. |
| File Version | publisher |
| PubMed ID | 30675987 |
| DOI | 10.1002/jbm.a.36618 |
| Web of Science KeyUT | 000462623800012 |
| Related Url | isVersionOf https://doi.org/10.1002/jbm.a.36618 |
| FullText URL | JMU46_4_449.pdf |
|---|---|
| Author | Takada, Saimon| Kato, Hironari| Saragai, Yosuke| Muro, Shinichiro| Uchida, Daisuke| Tomoda, Takeshi| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tanaka, Noriyuki| Okada, Hiroyuki| |
| Keywords | Contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) Pancreatic neuroendocrine neoplasm (PNEN) Time–intensity curve (TIC) analysis |
| Note | This is a post-peer-review, pre-copyedit version of an article published in Journal of Medical Ultrasonics. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10396-019-00967-x.| |
| Published Date | 2019-08-03 |
| Publication Title | Journal of Medical Ultrasonics |
| Volume | volume46 |
| Issue | issue4 |
| Publisher | Springer |
| Start Page | 449 |
| End Page | 458 |
| ISSN | 1346-4523 |
| NCID | AA11563281 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31377939 |
| DOI | 10.1007/s10396-019-00967-x |
| Web of Science KeyUT | 000487923000010 |
| Related Url | isVersionOf https://doi.org/10.1007/s10396-019-00967-x |
| FullText URL | ANL_46_6_927.pdf Fig_table.pdf |
|---|---|
| Author | Makihara, Seiichiro| Kariya, Shin| Noujima-Harada, Mai| Ohara, Nobuya| Naito, Tomoyuki| Matsumoto, Junya| Noda, Yohei| Okano, Mitsuhiro| Yoshino, Tadashi| Nishizaki, Kazunori| |
| Keywords | MTX-associated LPD Methotrexate Pulmonary nodules |
| Note | This fulltext will be available in Aug 2020| |
| Published Date | 2019-12-31 |
| Publication Title | Auris Nasus Larynx |
| Volume | volume46 |
| Issue | issue6 |
| Publisher | Elsevier |
| Start Page | 927 |
| End Page | 933 |
| ISSN | 03858146 |
| NCID | AA00061157 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 Elsevier B.V. All rights reserved. |
| File Version | author |
| PubMed ID | 30739816 |
| DOI | 10.1016/j.anl.2019.01.010 |
| Web of Science KeyUT | 000488997100018 |
| Related Url | isVersionOf https://doi.org/10.1016/j.anl.2019.01.010 |
| FullText URL | Xenobiotica_49_8_935.pdf |
|---|---|
| Author | Su Nwe San| Matsumoto, Jun| Saito, Yumi| Koike, Masako| Sakaue, Hiroaki| Kato, Yoshinori| Fujiyoshi, Masachika| Ariyoshi, Noritaka| Yamada, Harumi| |
| Keywords | CYP3As DAA HCV LC-MS/MS human liver microsomes metabolism pharmacogenetics |
| Published Date | 2018-11-08 |
| Publication Title | Xenobiotica |
| Volume | volume49 |
| Issue | issue8 |
| Publisher | TAYLOR & FRANCIS |
| Start Page | 935 |
| End Page | 944 |
| ISSN | 00498254 |
| NCID | AA00891766 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30227770 |
| DOI | 10.1080/00498254.2018.1524947 |
| Web of Science KeyUT | 000468066800007 |
| Related Url | isVersionOf https://doi.org/10.1080/00498254.2018.1524947 |
| FullText URL | JGastroenterol_54_11_1019.pdf Table.pdf Figure 1.jpg Figure 2.jpg Figure 3A.tif Figure 3B.tif supplemental figure 1.jpg |
|---|---|
| Author | Matsumoto, Kazuyuki| Ohara, Toshiaki| Fujisawa, Masayoshi| Takaki, Akinobu| Takahara, Masahiro| Tanaka, Noriyuki| Kato, Hironari| Horiguchi, Shigeru| Yoshida, Ryuichi| Umeda, Yuzo| Fushimi, Soichiro| Yagi, Takahito| Matsukawa, Akihiro| Okada, Hiroyuki| |
| Keywords | Immunohistochemistry PD-L1 Pancreatic cancer |
| Note | This fulltext will be available in Apr 2020| |
| Published Date | 2019-04-29 |
| Publication Title | Journal of Gastroenterology |
| Volume | volume54 |
| Issue | issue11 |
| Start Page | 1019 |
| End Page | 1028 |
| ISSN | 09441174 |
| NCID | AA10988015 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31032528 |
| DOI | 10.1007/s00535-019-01586-6 |
| Web of Science KeyUT | 000492169400008 |
| Related Url | isVersionOf https://doi.org/10.1007/s00535-019-01586-6 |
| FullText URL | IntJMolSci_20_8_1973.pdf |
|---|---|
| Author | Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Yoshida, Saori| Maeda, Hatsuhiko| Kawakami, Toshiyuki| Nagatsuka, Hitoshi| |
| Keywords | cell differentiation epithelial-mesenchymal interaction immunohistochemistry malignant transformation notch signaling odontogenic tumor pleomorphic adenoma |
| Published Date | 2019-04-23 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume20 |
| Issue | issue8 |
| Publisher | MDPI |
| Start Page | 1973 |
| ISSN | 14220067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 by the authors. |
| File Version | publisher |
| PubMed ID | 31018488 |
| DOI | 10.3390/ijms20081973 |
| Web of Science KeyUT | 000467648700171 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms20081973 |
| JaLCDOI | 10.18926/AMO/57377 |
|---|---|
| FullText URL | 73_5_457.pdf |
| Author | Iwamuro, Masaya| Takahara, Masahiro| Yamazaki, Tatsuhiro| Tanaka, Takehiro| Kondo, Yoshitaka| Hiraoka, Sakiko| Okada, Hiroyuki| |
| Abstract | A 60-year-old Caucasian male was diagnosed with lung adenocarcinoma and multiple metastases to the bone, spleen, and brain. He underwent radiotherapy for the brain and lumbar spine metastases, plus chemotherapy (cisplatin and pemetrexed). The chemotherapy was discontinued due to vomiting and hyponatremia, and nivolumab was then administered. Eight months later, 18F-fluorodeoxyglucose positron emission tomography showed tracer uptake in the colon. Colonoscopy revealed a reddish multinodular polyp in the sigmoid colon. The polyp showed irregular microvessels. No colonic mucosal surface structures were observed. Colonic metastasis of the lung carcinoma was highly suspected; the polyp was therefore surgically removed. The histological analysis revealed granulation tissue and suppurative inflammation without neoplastic changes. We diagnosed the lesion as a granulation polyp. Despite the difficulty in diagnosing these lesions due to their rarity and similarity to metastatic colon tumors, we suggest that recognizing the endoscopic features of the polyp surface may allow a preoperative diagnosis. |
| Keywords | colonoscopy colonic neoplasms granulation polyp |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-10 |
| Volume | volume73 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 457 |
| End Page | 461 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31649373 |
| Web of Science KeyUT | 000491886600012 |
