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Author Inoue, Akio|
Published Date 1943-09-30
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue9
Content Type Journal Article
Author Yamaguti, Manpei|
Published Date 1943-08-31
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue8
Content Type Journal Article
Author Suga, Seiziro|
Published Date 1943-07-31
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue7
Content Type Journal Article
Author Harada, H.|
Published Date 1943-06-30
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue6
Content Type Journal Article
Author Matsuoka, Takeo|
Published Date 1943-06-30
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue6
Content Type Journal Article
Author Arai, Yasushige|
Published Date 1943-06-30
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue6
Content Type Journal Article
Author Arai, Yasushige|
Published Date 1943-06-30
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue6
Content Type Journal Article
Author 岡山医学会|
Published Date 1943-05-31
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue5
Content Type Others
Author Matsuba, Shoichi|
Published Date 1943-05-31
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue5
Content Type Journal Article
Author Matsuba, Shoichi|
Published Date 1943-05-31
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue5
Content Type Journal Article
Author Tsukawaki, Tokutarô|
Published Date 1943-05-31
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue5
Content Type Journal Article
Author 田村 於兎|
Published Date 1943-04-30
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue4
Content Type Others
Author Okamoto, Shigeru|
Published Date 1943-04-30
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue4
Content Type Journal Article
Author Wada, Sunao| Takahasi, Keiji| Yamane, Kazuo|
Published Date 1943-04-30
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue4
Content Type Journal Article
Author Matsuba, Shoichi|
Published Date 1943-04-30
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue4
Content Type Journal Article
JaLCDOI 10.18926/AMO/43824
FullText URL 65_1_1.pdf
Author Han, Xiao-Jian| Tomizawa, Kazuhito| Fujimura, Atsushi| Ohmori, Iori| Nishiki, Tei-ichi| Matsushita, Masayuki| Matsui, Hideki|
Abstract Mitochondria are important cellular organelles in most metabolic processes and have a highly dynamic nature, undergoing frequent fission and fusion. The dynamic balance between fission and fusion plays critical roles in mitochondrial functions. In recent studies, several large GTPases have been identified as key molecular factors in mitochondrial fission and fusion. Moreover, the posttranslational modifications of these large GTPases, including phosphorylation, ubiquitination and SUMOylation, have been shown to be involved in the regulation of mitochondrial dynamics. Neurons are particularly sensitive and vulnerable to any abnormalities in mitochondrial dynamics, due to their large energy demand and long extended processes. Emerging evidences have thus indicated a strong linkage between mitochondria and neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and Huntington's disease. In this review, we will describe the regulation of mitochondrial dynamics and its role in neurodegenerative diseases.
Keywords mitochondria phosphorylation ubiquitination SUMOylation neurodegeneration
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2011-02
Volume volume65
Issue issue1
Publisher Okayama University Medical School
Start Page 1
End Page 10
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21339790
Web of Science KeyUT 000287620500001
Author 岡山医学会|
Published Date 1943-03-31
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue3
Content Type Others
Author Okamoto, Shigeru|
Published Date 1943-03-31
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue3
Content Type Journal Article
Author Sekida, Tsutomu|
Published Date 1943-02-28
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue2
Content Type Journal Article
Author Takai, Shigeo|
Published Date 1943-02-28
Publication Title 岡山医学会雑誌
Volume volume55
Issue issue2
Content Type Journal Article