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FullText URL K0006961_abstract_review.pdf K0006961_fulltext.pdf K0006961_summary.pdf
Author KANEDA, Daisuke|
Published Date 2024-03-25
Content Type Thesis or Dissertation
Grant Number 甲第6961号
Granted Date 2024-03-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
FullText URL K0006956_abstract_review.pdf K0006956_fulltext.pdf
Author CHAO, RUOYU|
Published Date 2024-03-25
Content Type Thesis or Dissertation
Grant Number 甲第6956号
Granted Date 2024-03-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2022 Chao, Nishida, Yamashita, Tokumasu, Zhao, Kudo and Udono.
FullText URL K0006953_abstract_review.pdf K0006953_fulltext.pdf K0006953_other_figure.pdf K0006953_other1_Supplementary Figures.pdf K0006953_other2_Supplementary Table.pdf K0006953_summary.pdf
Author YOSHIMOTO, Masashi|
Published Date 2024-03-25
Content Type Thesis or Dissertation
Grant Number 甲第6953号
Granted Date 2024-03-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2023 Elsevier B.V.
FullText URL fulltext.pdf
Author Yoshitomi, Aiko| Soga, Yoshihiko| Yamanaka-Kohno, Reiko| Morimatsu, Hiroshi|
Keywords Sensitivity Specificity Perioperative Oral management Screening Question
Note The version of record of this article, first published in Perioperative Medicine, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13741-024-00394-8|
Published Date 2024-05-06
Publication Title Perioperative Medicine
Volume volume13
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 36
ISSN 2047-0525
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38711163
DOI 10.1186/s13741-024-00394-8
Web of Science KeyUT 001214796400002
Related Url isVersionOf https://doi.org/10.1186/s13741-024-00394-8
FullText URL fulltext.pdf
Author Maekawa, Yuhi| Sakura, Sora| Furutani, Yuji| Fujihara, Rento| Sugime, Hisashi| Ohtsuki, Takashi| Kitamatsu, Mizuki|
Keywords peptide pyrene metal ion fluorescence
Published Date 2024-04-07
Publication Title Processes
Volume volume12
Issue issue4
Publisher MDPI
Start Page 746
ISSN 2227-9717
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
DOI 10.3390/pr12040746
Web of Science KeyUT 001211366700001
Related Url isVersionOf https://doi.org/10.3390/pr12040746
FullText URL fulltext.pdf
Author Nakata, Eiji| Sugihara, Shinsuke| Nakahara, Ryuichi| Katayama, Haruyoshi| Itano, Takuto| Ozaki, Toshifumi|
Keywords spinal metastases spinal instability neoplastic score radiotherapy posterolateral involvement of spinal elements risk factor
Published Date 2024-04-30
Publication Title Cancer Control
Volume volume31
Publisher SAGE Publications
ISSN 1073-2748
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38686892
DOI 10.1177/10732748241250219
Web of Science KeyUT 001210831600001
Related Url isVersionOf https://doi.org/10.1177/10732748241250219
FullText URL fulltext.pdf
Author Takagi, Kosei| Umeda, Yuzo| Yoshida, Ryuichi| Fuji, Tomokazu| Yasui, Kazuya| Yagi, Takahito| Fujiwara, Toshiyoshi|
Keywords Hepaticojejunostomy Robotic surgery Pancreatoduodenectomy Biliary complications
Note The version of record of this article, first published in Langenbeck's Archives of Surgery, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00423-023-03020-1|
Published Date 2023-07-20
Publication Title Langenbeck's Archives of Surgery
Volume volume408
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 284
ISSN 1435-2451
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37468703
DOI 10.1007/s00423-023-03020-1
Web of Science KeyUT 001032102900001
Related Url isVersionOf https://doi.org/10.1007/s00423-023-03020-1
FullText URL fulltext.pdf
Author Nakata, Noa| Okamoto, Ryuichi| Sumi, Tomonari| Koga, Kenichiro| Morita, Takeshi| Imamura, Hiroshi|
Keywords 2,2,2-trifluoroethanol cosolvent effects preferential binding parameter protein folding stability urea
Published Date 2023-09-25
Publication Title Protein Science
Volume volume32
Issue issue10
Publisher Wiley
Start Page e4763
ISSN 0961-8368
NCID AA10829011
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 37622187
DOI 10.1002/pro.4763
Web of Science KeyUT 001083988800003
Related Url isVersionOf https://doi.org/10.1002/pro.4763
FullText URL fulltext.pdf
Author Gohara, Yuma| Tomonobu, Nahoko| Kinoshita, Rie| Futami, Junichiro| Audebert, Léna| Chen, Youyi| Komalasari, Ni Luh Gede Yoni| Jiang, Fan| Yoshizawa, Chikako| Murata, Hitoshi| Yamamoto, Ken-ichi| Watanabe, Masami| Kumon, Hiromi| Sakaguchi, Masakiyo|
Keywords Breast cancer REIC/Dkk-3 PD-L1 Immune checkpoint Cancer therapy
Note The version of record of this article, first published in Journal of Molecular Medicine, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00109-023-02292-w|
Published Date 2023-03-04
Publication Title Journal of Molecular Medicine
Volume volume101
Issue issue4
Publisher Springer Science and Business Media LLC
Start Page 431
End Page 447
ISSN 0946-2716
NCID AA11034065
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 36869893
DOI 10.1007/s00109-023-02292-w
Web of Science KeyUT 000943221900001
Related Url isVersionOf https://doi.org/10.1007/s00109-023-02292-w
FullText URL fulltext.pdf
Author Saiga, Miho| Nakagiri, Ryoko| Mukai, Yuko| Matsumoto, Hiroshi| Kimata, Yoshihiro|
Keywords Patient-reported outcomes Breast reconstruction Breast cancer Quality of life Satisfaction
Note The version of record of this article, first published in International Journal of Clinical Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10147-023-02347-5|
Published Date 2023-05-09
Publication Title International Journal of Clinical Oncology
Volume volume28
Issue issue7
Publisher Springer Science and Business Media LLC
Start Page 847
End Page 859
ISSN 1341-9625
NCID AA11086579
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37160493
DOI 10.1007/s10147-023-02347-5
Web of Science KeyUT 000984738500001
Related Url isVersionOf https://doi.org/10.1007/s10147-023-02347-5
FullText URL fulltext.pdf
Author Matsushima, Ryo| Hisano, Hiroshi| Galis, Ivan| Miura, Satoko| Crofts, Naoko| Takenaka, Yuto| Oitome, Naoko F.| Ishimizu, Takeshi| Fujita, Naoko| Sato, Kazuhiro|
Note The version of record of this article, first published in Theoretical and Applied Genetics, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00122-023-04339-5|
Published Date 2023-04
Publication Title Theoretical and Applied Genetics
Volume volume136
Issue issue4
Publisher Springer Science and Business Media LLC
Start Page 94
ISSN 0040-5752
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37010621
DOI 10.1007/s00122-023-04339-5
Web of Science KeyUT 000962880600001
Related Url isVersionOf https://doi.org/10.1007/s00122-023-04339-5
FullText URL fulltext.pdf
Author Matsumura, Kentarou| Wakabayashi, Kyosuke| Kawakami, Renya| Miyatake, Takahisa|
Keywords Sexual selection Sexual conflict Geographic variation Tribolium castaneum
Note The version of record of this article, first published in Behavioral Ecology and Sociobiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00265-023-03359-x|
Published Date 2023-07
Publication Title Behavioral Ecology and Sociobiology
Volume volume77
Issue issue7
Publisher Springer Science and Business Media LLC
Start Page 85
ISSN 0340-5443
NCID AA00558665
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
DOI 10.1007/s00265-023-03359-x
Web of Science KeyUT 001024918000001
Related Url isVersionOf https://doi.org/10.1007/s00265-023-03359-x
FullText URL fulltext.pdf
Author Naito, Hidefumi| Sumi, Tomonari| Koga, Kenichiro|
Published Date 2024
Publication Title Faraday Discussions
Volume volume249
Publisher Royal Society of Chemistry (RSC)
Start Page 440
End Page 452
ISSN 1359-6640
NCID AA10836538
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Royal Society of Chemistry 2024
File Version publisher
PubMed ID 37791511
DOI 10.1039/d3fd00104k
Web of Science KeyUT 001077081700001
Related Url isVersionOf https://doi.org/10.1039/d3fd00104k
FullText URL fulltext20240423-01.pdf fig20240423-01.pdf table20240423-01.pdf suppl20240423-01.pdf
Author Hanzawa, Shunya| Kikuchi, Satoru| Kuroda, Shinji| Shoji, Ryohei| Kashima, Hajime| Matsumi, Yuki| Takahashi, Ayako| Kakiuchi, Yoshihiko| Takagi, Kosei| Tanabe, Shunsuke| Noma, Kazuhiro| Kagawa, Shunsuke| Shikata, Kenichi| Fujiwara, Toshiyoshi|
Note This is an Accepted Manuscript of an article published by Taylor & Francis in Nutrition and Cancer on 15 Apr 2024, available at: https://doi.org/10.1080/01635581.2024.2340782.| This fulltext file will be available in Apr. 2025.|
Published Date 2024-04-15
Publication Title Nutrition and Cancer
Volume volume76
Issue issue6
Publisher Informa UK Limited
Start Page 476
End Page 485
ISSN 0163-5581
NCID AA00325612
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 38619145
DOI 10.1080/01635581.2024.2340782
Web of Science KeyUT 001202947500001
Related Url isVersionOf https://doi.org/10.1080/01635581.2024.2340782
JaLCDOI 10.18926/AMO/66928
FullText URL 78_2_193.pdf
Author Kashima, Hajime| Teraishi, Fuminori| Matsumi, Yuki| Shimamura, Hiroshi| Fujiwara, Toshiyoshi|
Abstract Tailgut cyst is a rare cystic disease of the anterior sacral surface and the remains of an embryonic tail gut. Tailgut cysts have a potential for malignancy, and complete resection with an adequate surgical margin is necessary. Even if incomplete resection does not result in recurrence of malignant disease, there is a risk of local infection leading to refractory fistulas. The optimal treatment for such refractory recurrent lesions has not been reported. We describe a case in which the combination of laparoscopic and transsacral approaches was effective for resecting a recurrent refractory fistula after incomplete resection of a tail gut cyst.
Keywords tailgut cyst laparoscopic resection fistula formation
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 193
End Page 196
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688837
Web of Science KeyUT 001227932200003
JaLCDOI 10.18926/AMO/66927
FullText URL 78_2_185.pdf
Author Takahashi, Hiroko| Eguchi, Jun| Watanabe, Mayu| Nakayama, Masanori| Wada, Jun|
Abstract The global pandemic of coronavirus infection 2019 (COVID-19) was an unprecedented public health emergency. Several clinical studies reported that heart disease, lung disease, diabetes, hypertension, dyslipidemia, and obesity are critical risk factors for increased severity of and hospitalization for COVID-19. This is largely because patients with these underlying medical conditions can show poor immune responses to the COVID-19 vaccinations. Diabetes is one of the underlying conditions most highly associated with COVID-19 susceptibility and is considered a predictor of poor prognosis of COVID-19. We therefore investigated factors that influence the anti-SARS-CoV-2 spike IgG antibody titer after three doses of vaccination in patients with type 2 diabetes. We found that obesity was associated with low anti-SARS-CoV-2 spike IgG antibody titers following three-dose vaccination in type 2 diabetics. Obese patients with type 2 diabetes may have attenuated vaccine efficacy and require additional vaccination; continuous infection control should be considered in such patients.
Keywords obesity type 2 diabetes COVID-19 vaccination
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 185
End Page 191
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688836
Web of Science KeyUT 001227932200002
JaLCDOI 10.18926/AMO/66926
FullText URL 78_2_171.pdf
Author Kuramoto, Aya| Saito, Shinya| Watanabe, Kumi|
Abstract We investigated (i) the relationships among internalized stigma (IS), sense of coherence (SOC), and the personal recovery (PR) of persons with schizophrenia living in the community, and (ii) how to improve the support for these individuals. A questionnaire survey on IS, SOC, and PR was sent by mail to 270 persons with schizophrenia living in the community who were using psychiatric daycare services, of whom 149 responded and 140 were included in the analysis. We established a hypothetical model in which IS influences PR, and SOC influences IS and PR, and we used structural equation modeling to examine the relationships among these concepts. The goodness of fit was acceptable. Our findings suggest that rather than directly promoting PR, SOC promotes PR by mitigating the impact of IS. It is important for nurses/supporters to support individuals with schizophrenia living in the community so that they have opportunities to reflect on their own experiences through their activities and to share their experiences with peers. Nurses/supporters themselves should also reflect on their own support needs. Our findings suggest that this will lead to a reduction of IS and the improvement of SOC, which will in turn promote personal recovery.
Keywords schizophrenia internalized stigma sense of coherence personal recovery community
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 171
End Page 184
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688835
Web of Science KeyUT 001229151800009
JaLCDOI 10.18926/AMO/66925
FullText URL 78_2_163.pdf
Author Deguchi, Takayuki| Kanda, Kanae| Furusawa, Kazunari| Nlandu Roger Ngatu| Hirao, Tomohiro|
Abstract A spinal cord injury (SCI) can cause severe lifelong functional disability and profoundly affect an individual’s daily life. We investigated the prediction of patients’ post-SCI functional outcomes by evaluating sensory scores rather than motor scores, as the latter’s association with functional outcomes is well established. We examined patients’ responses to a light touch (LT) and pin prick (PP) at admission and the response data’s usefulness as predictors of functional outcomes (i.e., ability to perform activities of daily living) at discharge. This exploratory observational study used data from the Japanese National Spinal Cord Injury Database (SCI-J). Data from 3,676 patients who met the inclusion criteria and were admitted for an SCI between 1997 and 2020 were analyzed. The motor score of the Functional Independence Measure (mFIM) at discharge was used as an index of functional outcome. A multiple regression analysis revealed that the mFIM was associated with both the LT response (β=0.07 (0.01), p<0.001) and the PP response (β=0.07 (0.01), p<0.001) at admission. The false discovery rate log-worth values for LT and PP were 6.6 and 8.5, respectively. Our findings demonstrate that LT and PP scores at admission can help predict patients’ functional outcomes after an SCI, although the magnitude of their contributions is not high.
Keywords functional independence measure light touch pin prick spinal cord injury Japanese National Spinal Cord Injury Database
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 163
End Page 170
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688834
Web of Science KeyUT 001229151800008
JaLCDOI 10.18926/AMO/66924
FullText URL 78_2_151.pdf
Author Komatsubara, Tadashi| Tazawa, Hiroshi| Hasei, Joe| Omori, Toshinori| Sugiu, Kazuhisa| Mochizuki, Yusuke| Demiya, Koji| Yoshida, Aki| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Urata, Yasuo| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi|
Abstract Soft-tissue sarcoma (STS) is a heterogeneous group of rare tumors originating predominantly from the embryonic mesoderm. Despite the development of combined modalities including radiotherapy, STSs are often refractory to antitumor modalities, and novel strategies that improve the prognosis of STS patients are needed. We previously demonstrated the therapeutic potential of two telomerase-specific replication-competent oncolytic adenoviruses, OBP-301 and tumor suppressor p53-armed OBP-702, in human STS cells. Here, we demonstrate in vitro and in vivo antitumor effects of OBP-702 in combination with ionizing radiation against human STS cells (HT1080, NMS-2, SYO-1). OBP-702 synergistically promoted the antitumor effect of ionizing radiation in the STS cells by suppressing the expression of B-cell lymphoma-X large (BCL-xL) and enhancing ionizing radiation-induced apoptosis. The in vivo experiments demonstrated that this combination therapy significantly suppressed STS tumors’ growth. Our results suggest that OBP-702 is a promising antitumor reagent for promoting the radiosensitivity of STS tumors.
Keywords soft-tissue sarcoma radiotherapy oncolytic adenovirus p53 BCL-xL
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 151
End Page 161
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688833
Web of Science KeyUT 001229151800007
JaLCDOI 10.18926/AMO/66923
FullText URL 78_2_143.pdf
Author Shigematsu, Hisayuki| Yamashita, Natsumi| Suehisa, Hiroshi| Ueno, Tsuyoshi| Ryuko, Tsuyoshi| Sugihara, Takahito| Nakashima, Shohei| Sano, Yoshifumi| Yamashita, Motohiro|
Abstract Travel burden is a poor prognostic factor for many cancers worldwide because it hinders optimal diagnosis and treatment planning. Currently, the impact of travel burden on survival after surgery for non-small cell lung cancer (NSCLC) in Japan is largely unexplored. We examined the impact of travel distance on the postoperative outcomes of patients with NSCLC in Ehime Prefecture, Japan. The data of 1212 patients who underwent surgical resection for NSCLC were retrospectively reviewed. Patients were divided into quartiles based on the travel distance from their home to the hospital (≤ 13 km, 13-40 km, 40-57 km, and > 57 km) in Ehime Prefecture. We found no significant differences among the quartiles in baseline clinicopathological characteristics, including sex, smoking status, histology, surgical procedure, clinical stage, and pathological stage. Overall survival (OS) and relapse-free survival (RFS) also were not significantly different among the travel distance quartiles. We conclude that travel distance did not impact OS or RFS among patients with NSCLC who underwent surgical resection at our institution.
Keywords non-small cell lung cancer travel distance travel burden lung surgery surgical outcome
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 143
End Page 149
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688832
Web of Science KeyUT 001229151800006