遺伝性振顫症を思わせる一症例とその脳波に就いて

私は遺伝性振顫症と思われる一症例に遭遇した.本症例は,両下肢に,ミオクローヌス様痙攣を惹起し,その前後には特有なる脳波を示する.猶,家系には,遠隔地に居住する者が多く,詳細なる遺伝歴を調査することは出来なかつたが,検索し得られた症例をも附記して,ここに報告した.

Male, 72 years old farmor, Family history: His aunt, mother's elder sister (91 years) had "Nein Tremor" of the head in here about 32 years old. At the age of about 50 years she had tendon tremor on both hands which she still has today and she presents "Ja Tremor" of head. When she tries to do some thing this tremor is increased. Patient's youngest brother had cerebical ankylosis from the age of about 20 years, and therefore, when he wanted to look back he had to turn his whole body. However, both of them have otherwise no great inconvenience in their daily routines. The patient had suffered from arthritis-like piercing pain and neurasthenia of both lower limbs for the period of ten years starting from about his fortieth year. However, from the time when these pains had disappeared spontaneously, "Nein Tremor" of the head and expiratory dyspnea appeared. The tremor, persisting up to the present, increases in severity when he tries to do anything, but dyspnea disappeared spontaneously about two years after its onset. From the time of the disappearnce of dyspnea whenever he lies down on left side or on back in the afternoon, especially at night, to sleep, a most inexplicable unpleasant feeling begins to attack him first from head to breast, followed by myoclonus-like convulsive fit of both lower limbs. Both before and after the convulsive fit a peculiar abnormal eloctroencephalogram appears. However, when he changes his posture, the fit ceases and at the same time electreoncephalogram returns to normal.