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ID 56183
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72_4_427.pdf 2.38 MB
Author
Sekimizu, Masahiro Department of Pediatrics, Nagoya Medical Center
Fujimoto, Junichiro Department of Pathology, National Center for Child Health and Development
Takimoto, Tetsuya Center for Clinical Research and Development, National Center for Child Health and Development
Tsurusawa, Masahito Advanced Medical Research Center, Aichi Medical University
Horibe, Keizo Department of Clinical Research Center
Sunami, Shosuke Department of Pediatric Hematology Oncology, Japanese Red Cross Narita Hospital
Abstract
Pediatric patients with lymphoblastic lymphoma are generally treated using the Berlin-Frankfurt-Munster (BFM) 90 protocol, which is the standard treatment strategy for pediatric acute lymphoblastic leukemia, and have a favorable outcome. However, this intense regimen includes high total doses of anthracycline and alkylating agents, and is known to cause late complications. We therefore planned a clinical trial to examine the efficacy and safety of a modified BFM regimen. We expect that this phase II, nationwide multicenter trial will help to establish an effective and safer standard therapy for stage I/II pediatric lymphoblastic lymphoma.
Keywords
pediatrics
limited stage
lymphoblastic lymphoma
efficacy
safety
Amo Type
Clinical Study Protocol
Publication Title
Acta Medica Okayama
Published Date
2018-08
Volume
volume72
Issue
issue4
Publisher
Okayama University Medical School
Start Page
427
End Page
430
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
Copyright Holders
CopyrightⒸ 2018 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID