| ID | 54599 |
| JaLCDOI | |
| FullText URL | |
| Author |
Kanaya, Nobuhiko
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Aoki, Hideki
Department of Surgery, Iwakuni Clinical Center, National Hospital Organization
Yamasaki, Rie
Department of Pathology, Iwakuni Clinical Center, National Hospital Organization
Morihiro, Toshiaki
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Takeuchi, Hitoshi
Department of Surgery, Iwakuni Clinical Center, National Hospital Organization
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| Abstract | We report a case of a granulocyte colony-stimulating factor (G-CSF)-producing gallbladder tumor associated with fever in a middle-aged female. Preoperative blood analysis showed leukocytosis with elevated levels of C-reactive protein and G-CSF. We resected the liver at S4a＋S5, with regional lymph node dissection and partial resection of the duodenum. Histology revealed undifferentiated carcinoma with spindle and giant cells and papillary adenocarcinoma. Immunohistochemistry revealed Stage IIIB G-CSF-producing gallbladder cancer. Postoperatively, leukocyte and serum G-CSF levels decreased to within normal limits. Adjuvant gemcitabine chemotherapy was administered for 16 months, and she has been recurrence-free for 48 months.
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| Keywords | gallbladder cancer
G-CSF
unidentified fever
leukocystosis
adenocarcinoma
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| Amo Type | Case Reports
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| Publication Title |
Acta Medica Okayama
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| Published Date | 2016-10
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| Volume | volume70
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| Issue | issue5
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| Publisher | Okayama University Medical School
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| Start Page | 393
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| End Page | 396
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| ISSN | 0386-300X
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| NCID | AA00508441
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| Content Type |
Journal Article
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| language |
English
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| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School
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| File Version | publisher
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| Refereed |
True
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| PubMed ID | |
| Web of Science KeyUT |
