Elsevier BVActa Medica Okayama2950-2217322025Erythromelalgia presenting with posterior reversible encephalopathy syndrome: A pediatric case report100078ENKengoSuzukiDepartment of Pediatrics, Okayama University HospitalKazuhiroUdaDepartment of Pediatrics, Okayama University HospitalMitsuruTsugeDepartment of Pediatric Acute Diseases, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesKyosukeArakawaDepartment of Anesthesiology and Resuscitology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesKenjiShigeharaDepartment of Pediatrics, Okayama University HospitalTakafumiObaraDepartment of Emergency, Critical Care, and Disaster Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesKoseiHasegawaDepartment of Pediatrics, Okayama University HospitalHirokazuTsukaharaDepartment of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesBackground: Erythromelalgia is a rare disorder characterized by erythema, warmth, and burning pain in the extremities. We report a pediatric case of erythromelalgia in a patient who developed posterior reversible encephalopathy syndrome (PRES), without any cutaneous signs.<br>
Case presentation: A previously healthy 12-year-old girl presented to our pediatric clinic with burning extremity pain that had persisted for 6 weeks. The patient was treated with analgesics; however, the pain was refractory to these agents. Seven days after the first visit, she developed afebrile seizures and was transferred to our hospital. Her initial blood pressure was 139/105 mmHg (+2.0 SD), and brain magnetic resonance imaging revealed high intensity areas in the bilateral parietal and occipital lobes, leading to a diagnosis of PRES. Her blood pressure was difficult to control with anti-hypertensive agents. Burning pain in her extremities was relieved by cooling and worsened by warming. Although erythema was not observed in her hands or legs, erythromelalgia was suspected based on the characteristic nature of her pain. Intravenous lidocaine was administered for diagnosis, which was dramatically effective. After initiating mexiletine, the burning pain in her extremities disappeared, and hypertension improved. A final diagnosis of erythromelalgia with PRES was made.<br>
Conclusion: A history of temperature-dependent pain relief and deterioration are important indicators of disease diagnosis, even if patients indicate a lack of erythema or warmth. Physicians should be aware that persistent pain due to erythromelalgia can lead to refractory hypertension and development of PRES.No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026裏表紙・英文目次ENNo potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026奥付ENNo potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026Teaching and Learning：Japanese and International Student Collaboration in the Classroom209226ENAlexisPUSINAJunkoOTOSHI10.18926/70122This practical report introduces three intercultural collaborative trial classes designed to integrate Japanese and international students in first-year EFL classes. Using a CLIL-informed approach, the classes promoted intercultural understanding through culturally grounded activities and small-group communication tasks. Reflection surveys from both Japanese and international participants revealed overall positive experiences, with international students expressing strong enjoyment and Japanese students highlighting both linguistic gains and communication challenges. Analysis indicates that interaction across diverse cultural and linguistic backgrounds fostered intercultural awareness while motivating Japanese learners to further develop their speaking skills. The findings support the value of collaborative, content-based activities for enhancing intercultural understanding.No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026世界観光倫理憲章を踏まえたアクセシブルアウトドアツーリズムの検討 ―世界自然遺産地域でのアウトドア型車椅子を用いた実践を通じて―195208ENKosukeIKETANIGeneral Education and Global Studies Field, Okayama UniversityShinHARADAGeneral Education and Global Studies Field, Okayama UniversityKeitaKUSUNOKIInstitute of Student Support, Bukkyo University10.18926/70121アクセシブルアウトドアツーリズムを進めていくためには，「保全・保護」と「開発」の両立が非常に重要な観点となる。そこで本実践では，一人でも多くの人がアウトドア活動に参加できることを目指し，世界自然遺産地域においてアウトドア型車椅子を用いたツアーが実現できるかどうかを検討することとした。「誰ひとり取り残さない観光」とは，世界観光倫理憲章でも標榜された目標であるが，このことを実現するためには，今回検討を行ったような一つ一つの実践を積み重ねることによって，少しずつであってもアクセシブルアウトドアツーリズムの可能範囲を広げていくことが，最も確実な取り組みなのではないかと考えている。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026ピア・AI・教員の三者協働フィードバックによるライティング授業の再設計 ―AI利用の実践報告−174194ENMarikoUzukaInstitute for Promotion of Education and Campus Life10.18926/70120本稿は、アカデミック・ライティング授業におけるピア・AI・教員のそれぞれの役割と利用順序（自分→ピア→AI→（省察）→教員）を組み込んだ三者協働モデルを設計し、2024〜2025年度に実践した内容を報告する。授業後の学生アンケートでは、AIの即時性・精緻化が評価される一方、依存や有効性の限界に関する懸念も表明された。成績分布においては、AI導入後に下位層が縮小し、学習成果の底上げが示唆された。また、AI誤用や濫用を防ぐには、教室内で建設的な利用法の具体的な指導（例：例文より診断的フィードバックを重視、AI提案の採否理由のメタ記述）が効果的であった。これらの結果から、AIの利点を活かしつつ、学生の判断を中心に据えるライティング授業設計の有効性と課題を提示する。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026大学における中国語多読の試み155173ENTomomiISHIIInstitute for Promotion of Education and Campus Life, Okayama University10.18926/70119 This study examines the implementation of the instruction for extensive reading in Chinese among 19 learners who completed one year of beginner-level Chinese studies comprising two 100-minute sessions per week. Regarding survey methods, a questionnaire using a five-point Likert scale and open-ended responses was utilized. The findings revealed that learners recognized extensive reading as an effective strategy for improving their reading comprehension and vocabulary. However, some challenges exist, including the lack of suitable books for extensive reading practices and difficulties in sustaining extensive reading habits.No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026「知の探研」× 多文化共修 ―オンライン授業再構築の試み―145154ENYumikoYAMAMOTOFaculty of General and Global Studies (GDP), Okayama UniversityKha ManhNGUYENDiscovery Program for Global Learners, Okayama University10.18926/70118岡山大学では2025年4月入学生から新カリキュラムがスタートした。学士課程改革の一環として導入されたのが全学共通・課題探究科目「知の探研」である。本稿では，新入生対象科目である「知の探研」を，海外生を含むグローバル・ディスカバリー・プログラム生向けに英語で “Inquiries of Knowledge” として開講した初年度の取り組みを報告する。とりわけオンデマンド型オンライン授業を, 本学が推進する多文化共修の視点で再構築するにあたり，教材を単に英訳するのではなく, オンライン環境においても協働学習を実現する工夫や，言語的・文化的配慮の統合が不可欠であることを明らかにする。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026学部別インタビューによる学習者ナラティブとオリエンテーション実践 ―大学入学時における外国語学習動機づけ促進の試み―129144ENAzumiYOSHIDAInstitute for Promotion of Education and Campus Life, Okayama UniversityMasakoTERANISHIInstitute for Promotion of Education and Campus Life, Okayama University10.18926/70117岡山大学では新学習指導要領実施に合わせ、「学習者中心の学び」の実現を目指すTarget2025と呼ばれる方針のもと英語カリキュラムの改革を進めてきた。この改革では、英語系教員と各部局とが密に連携しながら、学士課程全体を通した英語学習を全学的に展開していくことに焦点を当てている。その取り組みの一環として、各部局から推薦を受けたロールモデルとの学部別インタビューを実施し、英語学習についての詳細を聴き取った。また、新入生への激励のメッセージ動画を作成し、英語授業オリエンテーションで上映した。本稿では、インタビューで得られたナラティブやオリエンテーション実施の経緯、また、オリエンテーション後に実施したアンケート結果について報告する。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026From The Odyssey to The Zahir：The Evolution of Penelopeia Across Time and Tradition120128ENSaidaKHALMIRZAEVAFaculty of General Education and Global Studies, Okayama University10.18926/70116The story of a man who leaves home and strives to return has become one of the most enduring narrative patterns in world literature and folklore. Across centuries and cultures, it has been retold in myths, epics, folktales, and modern fiction―the story of the homecoming hero who, after long absence and peril, finds his way back to the place and the person he once called his own. This study explores the persistence and transformation of this universal motif through a comparative reading of Homer’s The Odyssey and Paulo Coelho’s The Zahir. It examines the evolving image of the waiting wife―from Homer’s Penelopeia, emblem of chastity and endurance, to Coelho’s Esther, a modern woman of independence and choice. Despite differences in setting, voice, and moral vision, both works embody the same human longing: to return, to be recognized, and to rediscover love that endures time and change. Beneath their differences lies the same truth―the heart to which every journey, whether physical or spiritual, must ultimately return.No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026Developing a Short-form Scale to Assess Learner Beliefs Regarding English Learning Strategies100119ENHiroshiMORITANIInstitute for Promotion of Education and Campus Life, Okayama UniversityAlexisPUSINAInstitute for Promotion of Education and Campus Life, Okayama University10.18926/70115Questionnaire surveys are a prevalent method in applied linguistics for investigating complex constructs, such as learner beliefs. However, their complex nature often creates overly lengthy instruments, making them impractical for classroom use or for obtaining timely educational insights. This study aimed to develop a simplified, yet robust version of an existing learner belief scale to address these challenges. The authors carefully selected 24 belief-specific items from an initial pool of 78 items from a previous study for use in an online survey, which was completed by 246 participants. The data were subject to exploratory factor analysis. This process resulted in a concise 12-item scale, could offer a more practical tool for language educators.No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026発達障害を有する高校生の保護者による障害学生支援の認知度9199ENShinHARADAGeneral Education and Global Studies Field, Okayama UniversityKosukeIketaniGeneral Education and Global Studies Field, Okayama UniversityMegumiMATSUIGeneral Education and Global Studies Field, Okayama UniversityNaotoMOCHIZUKIHealth and Counseling Center, The University of Osaka10.18926/70114 本研究では，発達障害を有する高校生の保護者が，「大学等における障害学生支援や学生相談をどの程度知っているか」，「大学等における障害学生支援や学生相談の情報をどのように入手したか」，「大学等における障害学生支援や学生相談の情報収集をする上で，大学等にどのような情報発信を期待するか」について調査を行った。その結果，まだ保護者に対し，十分に大学の学生支援の情報が行き届いていないこと，学生支援に関する情報発信を行う説明会や相談会を行うことが保護者から期待されていること，発達障害を有する高校生の高大移行を促進するために，高校の先生方に対する情報発信も精力的に行ったり，高大連携の取り組みをより行う必要があること等が見出された。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026近代韓国の読本教科書『初等小学』の底本に関する再考7490ENAnkooLEEInstitute for Promotion of Education and Campus Life, Okayama University10.18926/70113 本稿では、近代韓国の読本教科書『初等小学』（1906）の編纂において参照されたと思われる日本の明治期読本教科書について比較・考察を行った。まず、文部省編纂の検定『尋常小学読本』（1887）と第1期国定『尋常小学読本』（1903）、さらに金港堂出版の『尋常国語読本』（1900）及び『高等国語読本』（1900）との関連性について、先行研究の議論を再検討した。そのうえで、新たに金港堂の『新体読本 尋常小学用』（1894）と普及舎の『尋常小学新読本』（1893）の2種を底本として確認することができた。『初等小学』において最も多く参照された明治期読本教科書は金港堂の『尋常国語読本』（1900）であり、『初等小学』は、金港堂と文部省の比較的新しい尋常小学用読本教科書を優先的に参照したと思われる。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026留学生受け入れにおける教員の判断基準 ―多くの留学生を受け入れている教員の視点から―5773ENTakaoINAMORIFaculty of General and Global Studies, Okayama University10.18926/70112 少子化は国内大学の定員充足率に深刻な影響を与えることから、留学生の受入増に期待が寄せられている。しかし、大学院教育において留学生受入に前向きな教員と、消極的な教員が見受けられる。本研究では、より多くの留学生を受け入れている教員が、どのような判断基準で受け入れを決定しているのかを、半構造化インタビューを通じて明らかにすることを試みた。その結果、判断基準に関しては、教員により表現は異なるが「人物」と「能力」を確認していることが分かった。また、受け入れを前向きに考える教員は、留学・在外研究員経験や、初めて受け入れた留学生指導を通じて良い経験をしたこと等が、留学生に対するプラスの印象をつくり、積極的な受け入れにつながっていることが明らかになった。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026自閉スペクトラム症特性と精神的健康の関連：自己理解による媒介効果の検討4156ENHirokiNISHIMURAInstitute for Promotion of Education and Campus Life, Okayama UniversityAkihiroUCHIDAOkayama Psychiatric Medical Center10.18926/70111 本研究は、自閉スペクトラム症特性と精神的健康の関連において、自己理解がどのような役割を果たすかを明らかにすることを目的とした。日本の成人604名のデータを利用した二次分析の結果、自閉スペクトラム症特性の高さと精神的健康の悪化との間には関連が認められた。この関連は、自己理解の肯定的側面によって部分的に媒介されることが示された。特にこの自己理解の保護的な効果は、男性よりも女性においてより強い可能性が示唆された。一方で、自己理解の否定的側面は媒介効果を示さなかった。これらの結果から、自閉スペクトラム症特性を持つ人々への支援において、肯定的な自己理解を促進することが重要であり、性差を考慮したアプローチの必要性が示唆された。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026オンラインによるボランティア日本語教室における参加者間のインターアクションの分析 ―地域型日本語教育の実現に向けて―3140ENMiwaSUESHIGEInstitute for Promotion of Education and Campus Life, Okayama University10.18926/70110 本研究では，地域型日本語教育のモデル構築に向け，地域型の特徴を有する教室内での支援者および参加者の発話や教授行動の傾向を明らかにすべく，外国語相互作用分析システムを用い，オンラインによるボランティア教室におけるインターアクションの分析を行った。分析の結果，（1）支援者の平均発話数が学習者より多いこと，（2）支援者の発話における間接的行動の割合が直接的行動よりもやや高いことが示された。「おしゃべり型の教育」では，学習者が伝えたいことを言語化していくプロセスの中で，間接的行動の下位分類の「質問」「学習者の意図の利用」「学習者の回答の繰り返し」等を支援者が積極的に使用し支援していることが分かった。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026心理臨床家同士のグループ体験における反省的実践1230ENRyosukeKOBASHIInstitute for Promotion of Education and Campus Life, Okayama UniversityMasashiTANAKATokai UniversityRinMURASEGraduate School of Education and Human Development, Nagoya University10.18926/70109 心理臨床家にとって反省的実践は重要であり，多様な形態のグループに参加をすることによって反省的実践を行っている。本研究では，全般的な心理臨床家同士のグループにおける体験（研究1）および継続的なグループにおける体験（研究2）を探索することを目的として，数名の心理臨床家による話し合いをKJ法を援用して分析した。その結果，心理臨床家同士のグループ体験における反省的実践には，【グループ体験が内省につながるかどうか】などの4つ側面が重要であることが示された。また，継続的なグループにおける体験では，《本来の人としての感覚や欲求》や《自分を不自由にしている要因》などの【会における気づき】が得られることが反省的実践として有意義であることが明らかになった。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026セクシュアリティのゆらぎと発達障害のADHDとの関連111ENMegumiMATSUIInstitute for Promotion of Education and Campus Life, Okayama University10.18926/70108 セクシュアリティのゆらぎと発達障害のADHDとの関連を明らかにするため，WEBによる縦断調査を行った。18歳以上の成人を対象とし，第1回目の調査は11,018人，1年後の第2回目の調査では5,474人から回答を得た。性自認，性的指向，性表現の様々なセクシュアリティについて，2回の調査での該当・非該当で4群に分け，ADHD得点について1要因の被験者間分散分析を行った。「デミロマンティック」「デミセクシュアル」以外で群の主効果が有意であり，「異性愛」「ゲイ」を除くセクシュアリティで，2回とも「非該当」群よりも「該当→非該当」群のADHD得点が有意に高かった。これによりセクシュアリティのゆらぎとADHDとの関連が示唆された。No potential conflict of interest relevant to this article was reported.岡山大学教育推進機構Acta Medica Okayama1881-595232026表紙・目次ENNo potential conflict of interest relevant to this article was reported.Elsevier BVActa Medica Okayama2949-774432025Efficient variant phasing utilizing a replication cycle reaction system103457ENAkihikoMitsutakeDepartment of Neurology, Graduate School of Medicine, The University of TokyoHiroyukiIshiuraDepartment of Neurology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical SciencesTakashiMatsukawaDepartment of Neurology, Graduate School of Medicine, The University of TokyoJunMitsuiDepartment of Precision Medicine Neurology, Graduate School of Medicine, The University of TokyoShojiTsujiDepartment of Precision Medicine Neurology, Graduate School of Medicine, The University of TokyoTatsushiTodaDepartment of Neurology, Graduate School of Medicine, The University of TokyoPurpose: When 2 heterozygous variants are detected in autosomal recessive disease genes, determining whether they are in cis or in trans is essential. Subcloning polymerase chain reaction products or complementary DNA is limited by variant distance (up to 10 kb) and complementary DNA availability. Droplet digital polymerase chain reaction, effective up to 100 kb, faces probe design challenges. We used replication cycle reaction (RCR), which replicates large DNA fragments based on E. coli chromosome replication, to phase widely spaced heterozygous variants.<br>
Methods: Circular DNA molecules were formed by ligating CRISPR/Cas9-cleaved genomic fragments with an oriC-AmpR cassette, then amplified by RCR. Using a genomic DNA (gDNA) sample that is previously analyzed by long-read sequencing, we optimized reaction conditions (including gDNA to oriC-AmpR cassette ratios) and validated phasing accuracy via electrophoresis and Sanger sequencing. Finally, we applied this method to 7 patients harboring 2 heterozygous pathogenic variants (4.3-152 kb apart).<br>
Results: RCR amplified genomic regions up to 104 kb. Lower gDNA-to-cassette ratios favored monoallelic amplification, enabling straightforward phasing, whereas higher ratios yielded biallelic products requiring transformation-based allele separation. For variants 152 kb apart, an intervening single-nucleotide variant enabled phased reconstruction. Ultimately, RCR confirmed compound heterozygosity in all 7 patients.<br>
Conclusion: This method effectively phases multiple heterozygous variants across large genomic distances.No potential conflict of interest relevant to this article was reported.Elsevier BVActa Medica Okayama2950-2535312026In memoriam, Nobuhiko Matsuo, 1931-2025100217ENToshihikoMatsuoHealthcare Science, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Department of Ophthalmology, Okayama University HospitalNo potential conflict of interest relevant to this article was reported.AME Publishing CompanyActa Medica Okayama2790-885232024Airway management during sedation for dental treatment in people with intellectual disabilities: a review28ENHitoshiHiguchiDepartment of Dental Anesthesiology, Okayama University HospitalYukikoNishiokaDepartment of Dental Anesthesiology, Okayama University HospitalSakiMiyakeDepartment of Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesTakuyaMiyawakiDepartment of Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesThe oral health of people with intellectual disabilities remains poor due to a complex combination of physical and social problems, and often requires invasive dental treatment. However, it can be difficult to obtain their cooperation for dental treatment because they may not fully understand the need for treatment or may experience high levels of anxiety due to lack of understanding and/or sensory aversions to stimuli present in the dental environment, and behavioral management is often necessary during such treatment. Sedation is a very useful patient management method for dental treatment for people with intellectual disabilities; however, the dental treatment-related sedation of people with intellectual disabilities has different characteristics to the dental treatment-related sedation of others or other procedure-related sedation. For example, deep sedation is required for behavioral management; drug interactions between the patient’s regular medications, such as antiepileptic and antipsychotic drugs, and anesthetics may make the depth of sedation deeper; and the prevalence rate of obesity is higher among people with intellectual disabilities. The fact that the patient is in the supine position with their mouth open also makes airway management during sedation for dental treatment more difficult. It is therefore imperative that airway management during dental treatment for people with intellectual disabilities be conducted with the utmost precision and vigilance. Various attempts have been made to improve airway management during such sedation, and new technologies, such as capnography, nasal high-flow systems, and acoustic respiration monitors, may help. The objective of this review is to enhance comprehension of the attributes of airway management in dental sedation for people with intellectual disabilities and to properly understand the usefulness of the techniques that have been attempted thus far to ensure safer and more secure airway management for this population. The ultimate goal is to provide them with safe and secure medical care and improve their health outcomes.No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所文化遺産マネジメント部門Acta Medica Okayama2758-963332025ARCH：岡山大学文明動態学研究所文化遺産マネジメント部門ニュースレター 第3号ENCultural Heritage Management Division, Research Institute for the Dynamics of Civilizations, Okayama UniversityNo potential conflict of interest relevant to this article was reported.MDPI AGActa Medica Okayama2079-6447342024N-Phenylphenothiazine Radical Cation with Extended π-Systems: Enhanced Heat Resistance of Triarylamine Radical Cations as Near-Infrared Absorbing Dyes350359ENMasafumiYanoFaculty of Chemistry, Material and Bioengineering, Kansai UniversityMinamiUedaFaculty of Chemistry, Material and Bioengineering, Kansai UniversityTatsuoYajimaFaculty of Chemistry, Material and Bioengineering, Kansai UniversityKoichiMitsudoDivision of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama UniversityYukiyasuKashiwagiOsaka Research Institute of Industrial Science and TechnologyN-Phenylphenothiazine derivatives extended with various aryl groups were designed and synthesized. These derivatives have bent conformation in crystal and exhibit high solubility. Radical cations obtained by one-electron oxidation of these derivatives gave stable radical cations in solution and showed absorption in the near-infrared region. A radical cation was isolated as a stable salt, which exhibited heat resistance up to around 200 °C. A design strategy for radical cation-based near-infrared absorbing dyes, which are easily oxidized and stable not only as a solution but in solid form, is described.No potential conflict of interest relevant to this article was reported.Japanese Society of Preventive MedicineActa Medica Okayama2758-7916312025The relationship between sleep disorder and dairy intake in university students of the nursing department in Japan3235ENShihoEdahiroDepartment of Nursing, Faculty of Medicine, Okayama UniversityMahoTakebayashiDepartment of Nursing, Faculty of Medicine, Okayama UniversityYuiKobayashiDepartment of Nursing, Faculty of Medicine, Okayama UniversityYokoTakahataDepartment of Nursing, Faculty of Medicine, Okayama UniversityThis study was conducted to clarify the relationship between sleep disorders and frequency, or timing of dairy intake with 192 university students in Japan. Pearson’s chi-squared test was carried out to find the relationship between two groups of sleep disorders and the timing of dairy product intake (p = 0.034, df = 4, χ2 = 10.38). The sleep disorder occurred significantly less if participants took a dairy product in the morning (p = 0.004) and significantly more when participants took a dairy product in the afternoon (p = 0.028). The findings showed that consuming dairy products in the morning is effective in treating sleep disorders.No potential conflict of interest relevant to this article was reported.Japanese Society of Preventive MedicineActa Medica Okayama2758-7916312025Relationship between media literacy and searching skills on report assignments in nursing students in Japan1121ENYuriiNagaoDepartment of Nursing, Faculty of Medicine, Okayama UniversityWakanaYanoDepartment of Nursing, Faculty of Medicine, Okayama UniversityYokoTakahataDepartment of Nursing, Faculty of Medicine, Okayama UniversityObjective: This study evaluates the relationship between information access and media literacy attitudes. We also assessed the impact of “Medical Literature Reading” on media literacy among Japanese university students. Methods: A cross-sectional study was conducted from April 2–16 and from August 2–16, 2024. A self-reporting questionnaire, including the school year, was used to determine if participants had taken the “Medical Literature Reading” course and to identify the sources often used for reporting assignments and media literacy. Results: This study included 195 subjects. The differences in media literacy scores between school years were analyzed. The total scores of fourth-year students were significantly higher than those of first-year on the media literacy scale (p = 0.014). The differences in media literacy scores among students enrolled in “Medical Literature Reading” were analyzed. The scores on the media literacy scale (p = 0.006) were significantly higher in participants than in non-participants. The relationships among the three groups by sources used for report assignments, school years (χ2(6) = 42.101, p < 0.0001), and history of taking “Medical Literature Reading” (χ2(2) = 7.048, p = 0.030) were also analyzed. Conclusions: Media literacy improved with schooling. Certain report assignments and subjects related to information literacy were found to have affected media literacy. Combining continuing experience and knowledge can lead to improvements in media literacy.No potential conflict of interest relevant to this article was reported.老年人文学研究会Acta Medica Okayama2435-574732024裏表紙・英文目次ENNo potential conflict of interest relevant to this article was reported.老年人文学研究会Acta Medica Okayama2435-574732024投稿規程・奥付ENNo potential conflict of interest relevant to this article was reported.老年人文学研究会Acta Medica Okayama2435-574732024迷惑をかけたくない意識の形成―教育との関係―2254ENXiaofanDENG10.18926/JHG/68714No potential conflict of interest relevant to this article was reported.老年人文学研究会Acta Medica Okayama2435-574732024西田幾多郎臨終記121ENRyozoSUZUKIKoichiroYAMAMOTOMikakoOBIKA10.18926/JHG/68713No potential conflict of interest relevant to this article was reported.老年人文学研究会Acta Medica Okayama2435-574732024表紙・目次ENNo potential conflict of interest relevant to this article was reported.MDPIActa Medica Okayama2673-7078342023Estimation of the Effects of Achilles Tendon Geometry on the Magnitude and Distribution of Local Strain: A Finite Element Analysis583595ENShotaEnomotoInstitute for Promotion of Education and Campus Life, Okayama UniversityToshiakiOdaGraduate School of Education, Hyogo University of Teacher EducationWe investigated the influence of Achilles tendon (AT) geometry on local-strain magnitude and distribution during loading, using finite element analysis. We calculated the following eight AT parameters for 18 healthy men: thickness and width of the most distal part, minimum cross-sectional area (mCSA), and most proximal part; length; and position of the mCSA. To investigate the effect of AT geometry on the magnitude and distribution of local strain, we created three-dimensional numerical models by changing the AT parameter values for every one standard deviation (SD) in the range of ±2 SD. A 4000 N lengthening force was applied to the proximal surface of all the models. The mean first principal strain (FPS) was determined every 3% of the length. The highest FPS in each model was mainly observed in the proximal regions; the 86–89% site (the most proximal site was set at 100%) had the highest number of models with the highest FPS (nine models). The highest FPS was observed in the model with a distal thickness of −2 SD, which was 27.1% higher than that of the standard model observed in the 2–5% site. Therefore, the AT geometry influences local-strain magnitude and distribution during loading.No potential conflict of interest relevant to this article was reported.WileyActa Medica Okayama2769-2558332024Forgetfulness in adult attention-deficit/hyperactivity disorder masks transient epileptic amnesia: a case reporte70003ENTakashiFukaoDepartment of Neuropsychiatry, OkayamaUniversity HospitalMasakiFujiwaraDepartment of Neuropsychiatry, OkayamaUniversity HospitalYutoYamadaDepartment of Neuropsychiatry, OkayamaUniversity HospitalShinjiSakamotoDepartment of Neuropsychiatry, OkayamaUniversity HospitalYosukeMatsumotoOkayama University Hospital Gender CenterManabuTakakiDepartment of Neuropsychiatry, OkayamaUniversity Faculty of Medicine, Dentistry andPharmaceutical SciencesBackground: Inattention due to attention-deficit/hyperactivity disorder (ADHD) can lead to forgetfulness. Transient epileptic amnesia (TEA) can cause forgetfulness, similar to ADHD. We report a patient with ADHD who developed TEA.<br>
Case Presentation: The patient was a 40-year-old woman with ADHD. She has been prone to forgetfulness since childhood. Two years before visiting our outpatient clinic, she had begun to occasionally forget events that had occurred several days earlier. However, she was largely unaware of the emergence of new amnestic symptoms. She had also begun to experience various other amnestic symptoms 2 months before she visited our clinic, which prompted her to visit our outpatient clinic. The combination of a detailed interview, electroencephalography (EEG) examination, and consideration of TEA enabled us to diagnose her with TEA and provide treatment accordingly. In our patient, daily forgetfulness due to ADHD delayed the recognition of new additional forgetfulness attributed to TEA.<br>
Conclusion: Psychiatrists need to consider TEA when patients with ADHD present with changes in or exacerbation of forgetfulness. We report a patient with ADHD who developed TEA. In our patient, daily forgetfulness due to ADHD delayed the recognition of new additional forgetfulness attributed to TEA. Psychiatrists need to consider TEA when patients with ADHD present with changes or exacerbation of forgetfulness. No potential conflict of interest relevant to this article was reported.WileyActa Medica Okayama2768-0622322023Clinical application of pancreatic juice-derived small extracellular vesicles of pancreatic ductal adenocarcinomae177ENKoichiroTsutsumiDepartment of Gastroenterology, Okayama University HospitalMotoyukiOtsukaDepartment of Gastroenterology, Okayama University HospitalBackground: Recent imaging modalities have helped inthe early detection of pancreatic ductal adenocarcinoma (PDAC), resulting inimproved survival rates for patients with early-stage PDAC. However, preoperative pathological diagnosis of early-stage PDAC remains a challenge, particularly for small PDAC that is difficult to diagnose through standardendoscopic ultrasound-guided fine-needle biopsy. In this context, pancreaticjuice cytology has been re-evaluated as an important tool for the preoperativediagnosis of early-stage PDAC.<br>
Main: Pancreatic juice (PJ) comes in directcontact with PDAC lesions in the pancreatic duct and thus may contain a fewHG-PanIN/PDAC cells and specific molecules. Additionally, the PJ may containconcentrated small extracellular vesicles (sEVs) that are released from cancerlesions. sEVs are double-layered lipid-bound particles that contain cargoassociated with the cell-of-origin, including proteins, microRNA, and RNA. sEVsreleased from cancer lesions found in body fluids, such as blood, urine, andsaliva, have already been studied as potential sources of diagnostic biomarkersfor cancer. PJ-derived sEVs could serve as a “liquid biopsy” for theearly diagnosis of PDAC. However, little is known about the existence,physiological status, and function of PJ-derived sEVs and their potentialutility as biomarkers for diagnostic, surveillance, and monitoring purposes oras therapeutic targets.<br>
Conclusion: PJ-derived sEVs represent a promisingavenue for the early diagnosis of PDAC. The utility of these particles as biomarkersfor diagnostic, surveillance, and monitoring purposes, or as therapeutictargets, warrants further research. Understanding the existence, physiologicalstatus, and function of PJ-derived sEVs is crucial to unlocking their potentialas a valuable tool for overcoming PDAC.No potential conflict of interest relevant to this article was reported.岡山大学文学部学芸員課程Acta Medica Okayama32014学芸員課程 Newsletter 第3号EN10.18926/66806No potential conflict of interest relevant to this article was reported.岡山大学教育学部附属教育実践総合センター心理教育相談室Acta Medica Okayama2185-512932005「事例報告」における各回のセッションの書き方3745EN10.18926/66590 事例報告や事例研究において，各回のセッションをどのように記述するかは，初心の執筆者にとって悩みの種である。面接場面を活き活きと再現しようとすると，クライエントの発言を多く採録したくなり，１回分の記述が膨大になって，焦点がぼやけ，冗長な報告となってしまう。投稿規定に従って短くしようとすると，事実が列挙されるだけの無味乾燥な記述になったり，重要なやりとりが失われたりする。本稿では「論文の目的や考察内容から，面接での発言や現象を絞り込み，経過を要約する」という基本的な観点は棚上げし，あくまで「技術論」として各回のセッションを短くわかりやすく記述するにはどうすればよいか，実例を例示して論じた。No potential conflict of interest relevant to this article was reported.岡山大学教育学部附属教育実践総合センター心理教育相談室Acta Medica Okayama2185-512932005性暴力の被害者カウンセリングから学んだこと―被害経験の本質とカウンセリングの要点―2535EN10.18926/66589 筆者は犯罪被害者カウンセラーの臨床実践を行ってきた。本論文では性暴力の被害者が被害後にどのような経験をしているかということと性暴力のカウンセリングの要点について学んだことをまとめることを目的とした。性暴力の本質は暴力と恐怖であり，その支援のためにはカウンセリングと平行して，さまざまの直接支援もオプションとして必要になる。箪者の行った様々の危機介入の経験をベースにしながら，性暴力の被害者に対する緊急カウンセリングの要点を暫定的にまとめたものである。オフィスでの個人カウンセリングが軸になっているが，臨床心理学的なコミュニティ支援の発想と方略が同時に求められる。No potential conflict of interest relevant to this article was reported.岡山大学教育学部附属教育実践総合センター心理教育相談室Acta Medica Okayama2185-512932005青年期用ハーディネス尺度 (Personality Hardiness Inventory for Adolescence : PHIA) の作成1724EN10.18926/66588 本研究の目的は，青年を対象に， Kobasa (1979a) の定義にもとづいた青年期用ハーディネス尺度の作成を行うことであった。大学生554名（男性202名，女性349名，不明３名）を対象に，データの収集を行ったところ， ３因子27項目からなる青年期用ハーディネス尺度 (Personality Hardiness Inventory for Adolescence: PHIA-27) が構成され，信頼性と妥当性が確認された。さらに本尺度の簡易化を試行したところ，同様の因子構造を有するPHIA-15を確認することができた。PHIA-27，同15ともに，抽出された３因子は，いずれも従来のハーディネス概念に対応したコミットメント，チャレンジ，コントロールの要素を抱合していた。No potential conflict of interest relevant to this article was reported.ElsevierActa Medica Okayama2666-9145332023Epiretinal Membrane Impairs the Inner Retinal Layer in a Traction Force-Dependent Manner100312ENYukiKanzakiDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityRyoMatobaDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityShuheiKimuraDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityMio M.HosokawaDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityYusukeShiodeDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityShinichiroDoiDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityTetsuroMoritaDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversitySayumiKanzakiDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityIppeiTakasuTakasu Eye ClinicAtsuhiroTanikawaDepartment of Ophthalmology, Fujita Health University Bantane HospitalYukiMorizaneDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityPurpose: To investigate the relationship between retinal traction force and impairment of the inner retinal layer in patients with epiretinal membrane (ERM).<br>
Design: Nonrandomized, retrospective consecutive case series.<br>
Participants: Two hundred nine eyes of 201 patients with idiopathic ERM who underwent vitrectomy for idiopathic ERM were enrolled.<br>
Methods: Retinal folds caused by ERM were visualized using en face OCT, and the maximum depth of retinal folds within the parafovea (MDRF) was measured. Focal macular electroretinogram (ERG) was used to measure the amplitude and implicit time of each component for the ERM eyes and the normal fellow eyes. B-scan OCT images were used to measure the thicknesses of the inner nuclear layer (INL) and outer nuclear layer (ONL) + outer plexiform layer (OPL). Expression of α-smooth muscle actin (α-SMA) in surgically removed ERM specimens was quantified by reverse-transcription polymerase chain reaction.<br>
Main Outcome Measures: We analyzed the relationship between MDRF and the relative amplitudes of focal macular ERG (affected eye/fellow eye), the relationships between MDRF and the mean INL thickness and ONL+OPL thickness, comparison of INL thickness and ONL+OPL thickness for each area when cases were classified according to MDRF localization in the ETDRS chart, and the relationship between MDRF and the relative expression of α-SMA in the ERM specimens.<br>
Results: The MDRF significantly correlated with the relative amplitudes (affected eye/fellow eye) of b-waves and oscillatory potentials (r = −0.657, P = 0.015; r = −0.569, P = 0.042, respectively) and the mean INL thickness and ONL+OPL thickness (r = 0.604, P < 0.001; r = 0.210, P = 0.007, respectively). However, only the INL thickness progression rate was significantly correlated with the MDRF progression rate (r = 0.770, P < 0.001). On case stratification by localization of MDRF based on the ETDRS chart, in regions other than temporal regions, the INL thickness was significantly greater in regions with MDRF than in other regions. The MDRF significantly correlated with α-SMA expression in the ERM specimens (r = 0.555, P = 0.009).<br>
Conclusions: The findings suggest that ERM impairs the inner retinal layer in a traction force-dependent manner.<br>
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
No potential conflict of interest relevant to this article was reported.ElsevierActa Medica Okayama2666-9145332023Quantitative Analyses of Retinal Traction Force and Metamorphopsia in Lamellar Macular Hole and Related Diseases100305ENMaiMinoDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityRyoMatobaDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityYukiKanzakiDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityShuheiKimuraDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityMio M.HosokawaDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityYusukeShiodeDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityTetsuroMoritaDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityYukiMorizaneDepartment of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityPurpose: To investigate the involvement of retinal traction in the pathogenesis of lamellar macular hole (LMH) and related diseases based on OCT–based consensus definition. <br>
Design: Retrospective, observational study. <br>
Participants: Seventy-two eyes with LMH, epiretinal membrane foveoschisis (ERM-FS), or macular pseudohole (MPH). <br>
Methods: To quantitatively evaluate the involvement and strength of retinal traction in their pathogenesis, retinal folds were visualized with en face OCT imaging, and the maximum depth of the parafoveal retinal folds (MDRF) was measured. Metamorphopsia was quantified by measuring the minimum visual angle of dotted lines needed to cause it to disappear using M-CHARTS (Inami). <br>
Main Outcome Measures: Maximum depth of retinal folds and M-CHARTS scores. <br>
Results: Of the 72 eyes, 26 were classified as having LMH, 25 as having ERM-FS, and 21 as having MPH. Parafoveal retinal folds were observed in 7 (26.9%) eyes with LMH, 25 (100%) with ERM-FS, and 21 (100%) with MPH. The MDRF (7.5 ± 17.6 μm) was significantly smaller in LMH than in ERM-FS (86.3 ± 31.4 μm) and MPH (74.5 ± 24.6 μm) (both P < 0.001), whereas no significant difference in MDRF between MPH and ERM-FS was observed (P = 0.43). A significant positive correlation between MDRF and M-CHARTS scores was observed in ERM-FS and MPH (P = 0.008 and 0.040, respectively) but not in LMH (P = 0.073). <br>
Conclusions: Retinal traction was significantly weaker in the LMH group than in the ERM-FS and MPH groups. The MDRF was significantly associated with the degree of metamorphopsia in the ERM-FS and MPH groups. These results provide insights into the diseases’ pathophysiology and treatment strategy. <br>
Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024大門正克・岡田知弘・川内淳史・河西英通・高岡裕之編『「生存」の歴史をつなぐ：震災10年、「記憶のまち」と「新たなまち」の交差から』315316ENKatsunoriIMAZU新刊紹介 (New Book)10.18926/66203No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024渡辺信一郎著『中国古代国家論』308314ENFuminoriTSUCHIGUCHI書評 (Book Review)10.18926/66202No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024「玉計算簿」と娼妓の生活 ―岡山大学附属図書館所蔵「遊廓業関係史料（仮）」にみる―299307ENMikakoSAWAYAMA資料紹介 (Materials and data)10.18926/66201No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024建白書ヲ読ミテ ―識語の語るもの―290298ENHiroshiYAMASHITA資料紹介 (Materials and data)10.18926/66200No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024備陽国学記録（三）154289ENKatsunaoKURACHI資料紹介 (Materials and data)10.18926/66199No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024玉：ヒスイとネフライト−石材の科学分析を通してつながる世界と日本の考古学−141153ENYoshiyukiIIZUKA展望：文明動態学研究所第１回特別展 津島から世界へ、世界から津島へ (Perspectives: From Tsushima to the world and from the world to Tsushima)10.18926/66198No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024趣旨説明134140ENNaokoMATSUMOTO展望：文明動態学研究所第１回特別展 津島から世界へ、世界から津島へ (Perspectives: From Tsushima to the world and from the world to Tsushima)10.18926/66197No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024活動紹介 西日本豪雨による被災と地域文化の再構築―愛媛県大洲市阿蔵の古学堂の事例を中心に―119133ENMorimichiTOKIWAINaohiroSHIRAISHITakahisaOMOTO特集：災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society)10.18926/66196No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024資料紹介 小松藩会所日記に見る伊予の災害―享保の飢饉対応を中心に―92118ENHikaruEBESU特集：災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society)10.18926/66195No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024明治期における水利・洪水と千住中組高尾家―見沼代用水を事例に―7991ENShojiMIMURANational Defense Academy of Japan特集：災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society)10.18926/66194This paper examines the maintenance work of the Minuma Substitute Canal by the Meiji Government and how Noriyoshi Takao who lived at Senjū-nakagumi was involved in it. In the 1880s, when the cost of maintaining the Minuma Substitute Canal was shifted from government expenditures to private ones, the early modern water usage system was on the verge of being converted to a modern one. This meant that the system, which was based on villages or ryō (領), transformed into one based on individuals, especially landowners. The village served as a cost-sharing unit during the Meiji period. Ryō (領) were operated in the downstream water of the Minuma Substitute Canal where there were no critical structures. However, districts (郡) supervised the water usage of ryō, creating a multilayered local community in terms of water usage.No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024明治期の災害情報と記録化―遠藤允信の情報活動とその背景―6778ENMasashiAMANONational Museum of Japanese History特集：災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society)10.18926/66193This paper focuses on the recording and transmission of disaster information, and examines the accumulation of disaster information, its trends, and the intentions behind its accumulation through a survey of information records accumulated by individuals during the Meiji period. Endō Sanenobu, the subject of this paper, was active mainly in Kyoto during the Meiji period (1868-1912), and in the course of his activities, he accumulated a vast amount of information records called the Seizan Manroku (静山漫録), including records of his investigations of ancient documents handed down in various places and verification records of folk tales and customs passed down in various places. In the course of accumulating such information, he became increasingly interested in disaster information after the Yodogawa river flood in Osaka in 1885, and eventually began to compile a series of Suiin Hikkai（酔蚓筆芥）on disaster information as his main theme. The series of information activities by Sanenobu were also supported by the development and diffusion of information media during that period. At the same time, the fact that Sanenobu paid attention to disaster information among various types of information suggests that he regarded disasters as an important turning point in his understanding of national and social changes. Through this information, the reality of people's social perceptions formed by the media will be revealed.No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024中洲の形成と中世後期の地域変容6066ENToshifumiYATANiigata University, Humanities and Social Sciences特集：災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society)10.18926/66192The purpose of this paper is to clarify how a harbor city established in a sandbank inlet transformed a local area. In the Later Medieval period, the harbor city of Nakamura was established in the lower part of the Chikusa river. In the late 15th century, the Eiōji temple of Jōdo Shinshū Buddhism was constructed in the harbor city of Nakamura. Nakamura used Sagoshinoshō as a local name. In the 16th century, the harbor city of Kariya on the west coast of the Chikusa river also used the local name of Sagoshinoshō. In the early modern period, villages to the west of the mouth of the Chikusa river came to use the local name of Sagoshinoshō. While the local name of the west coastal area of the Chikusa river mouth had been Akōnoshō, it changed to Sagoshinoshō. Areas where local names may have changed also include Shikatanoshō and Mikuriyanoshō elsewhere in the Later Medieval period.No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024災害と人間の暮らし5559ENKatsunoriIMAZU特集：災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society)10.18926/66191No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024飛鳥時代前半における備前産須恵器の宮都流入過程4154ENOsamuKIMURAOkayama University, Research Institute for the Dynamics of CivilizationMasakazuBABASabukaze pottery centerMinoruMORIKAWANara National Research Institute for Cultural Properties研究ノート (Research note)10.18926/66190In this paper, we attempt to reconstruct the process by which Bizen Sue ware flowed into the palace capital in the early 7th century, the first half of the Asuka period. Among the large lids collected from the Sazarashi Nakaike Kiln in Setouchi City, Okayama Prefecture, we found one that closely resembles the lids unearthed in the southern part of the Nara Basin, the Asuka Fujiwara area, and it is now clear that Sue ware was supplied to the capital from the Bizen area in the eastern part of Okayama Prefecture. The supply of Sue ware from the Bizen area to the Asuka Fujiwara area may date back to the first half of the Asuka period. It has been suggested that the supply of Sue ware to the imperial capital became active in the latter half of the Asuka period, but the results of this paper clarify that the Bizen area was supplying Sue ware to the palace capital before such large-scale supply began. It is highly likely that the supply of Sue ware to the palace capital in the first half of the Asuka period became the basis for the mass supply seen in the latter half.No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024文禄五年閏七月九日の伊予・豊後地震に関する特性化震源モデルを用いた中央構造線活断層帯の断層パラメータの検証2140ENYurieOKUMASchool of Science, Okayama UniversityTakashiKUMAMOTOSchool of Science, Okayama University論文 (Research article)10.18926/66189The purpose of this study is to verify the fault length and earthquake magnitude of the Iyo-Bungo earthquake in 1596 estimated by Ishibashi (2019) using historical documents written in the same period. According to Ishibashi (2019), the length of the source fault was estimated to have been less than 100 km and the earthquake magnitude was roughly estimated to have been around 7.5. In order to attempt to reproduce the interpretation, we conducted two different strong ground motion simulations: the attenuation equation method and the characterized source model method, both used in the Headquarters for Earthquake Research Promotion. We simulated earthquake ground motions based on several source fault models including estimation by Ishibashi (2019). For the length of the fault, a 100 km length corresponding to the Iyonada segment of the Median Tectonic Line active fault system was the first model and 130 km and 160 km models extending onshore to the northeast were taken into account as epistemic uncertainties. Regarding the dip angle of the fault, both 40 and 90 degree models were considered also as epistemic uncertainties. Our calculation with other uncertainties shows that the models with a fault length of 100 km with a dip angle of 90 or 40 degrees are consistent with the seismic intensity and seismogenic fault length of offshore fault estimated by Ishibashi (2019) based on reliable first-grade documents. If low-certainty intensity estimates by Ishibashi (2019) are used to evaluate fault length in our calculation, the possibility of 130 or 160 km length models with additional onshore faults will remain. Our results show that the strong ground motion simulation could reinforce the expert’s interpretation of historical documents and propose quantitative source fault models for historical earthquakes.No potential conflict of interest relevant to this article was reported.岡山大学文明動態学研究所Acta Medica Okayama2436-832632024How is subjective well-being affected by different factors and groups: Income threshold induces asymmetric effects120ENMasaoTSURIFaculty of Economics, MUSASHI UNIVERSITYKenAOOGraduate School of Humanities and Social Sciences, OKAYAMA UNIVERSITY論文 (Research article)10.18926/66188Holistic well-being has rapidly developed in the 21st century as a policy measurement tool. Nevertheless, there continue to be some gaps in the literature regarding the interrelation between subjective well-being and other factors, and, regarding disaggregation of the well-being status within a country, by age group, gender, and community. This study first illustrates how the concept of well-being developed from a philosophical and psychological conception of “happiness” to being measured by multidimensional tools that measure the impact of policy and the progress of society, such as OECD’s Better Life Index, UK’s National Well-being Measurement, and Japan’s Well-being Survey and Quality of Life. Subsequently, it analyzes the relationships between subjective well-being and objective variables by comparing the country, regional, and individual datasets. It found that some indicators, such as social relationships, have asymmetric effects on life satisfaction depending on the income level or threshold. In other words, if the income is less than a certain level, the effects of some indicators on life satisfaction are complementary to income, while if the income is above that level, the effects are substitutional. Finally, it estimates these effects and confirms them statistically by using the OECD Regional Statistics. Regarding the relationship between social connection and self-evaluation of life satisfaction rated on a 10-point Likert scale, the base score in the estimation is approximately 5.1 points higher in the lowest quartile group of income. However, the substitution is lower than that of the other groups by approximately -0.061. The coefficient of social connection for the other groups was approximately 0.059, and the lowest group had almost zero coefficients for substitution.No potential conflict of interest relevant to this article was reported.Cell PressActa Medica Okayama2666-1667342022A protocol to induce expandable limb-bud mesenchymal cells from human pluripotent stem cells101786ENTomokaTakaoDepartment of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesDaisukeYamadaDepartment of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesTakeshiTakaradaDepartment of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesHere, we present a protocol for the selective differentiation of human pluripotent stem cells mimicking human developmental processes into expandable PRRX1+ limb-bud mesenchymal (ExpLBM) cells. This approach enables expansion through serial passage while maintaining capacity for chondrogenic differentiation. For complete details on the use and execution of this protocol, please refer to Yamada et al. (2021, 2022).No potential conflict of interest relevant to this article was reported.American Chemical SocietyActa Medica Okayama2694-2453352023Highly Stretchable Stress-Strain Sensor from Elastomer Nanocomposites with Movable Cross-links and Ketjenblack394405ENRyoheiIkuraDepartment of Macromolecular Science, Graduate School of Science and Forefront Research Center for Fundamental Sciences, Osaka UniversityKotaKajimotoDepartment of Macromolecular Science, Graduate School of Science, Osaka UniversityJunsuParkDepartment of Macromolecular Science, Graduate School of Science and Forefront Research Center for Fundamental Sciences, Osaka UniversityShunsukeMurayamaGraduate School of Organic Materials Engineering, Yamagata UniversityYuseiFujiwaraDepartment of Mechanical Engineering, Osaka Institute of TechnologyMotofumiOsakiDepartment of Macromolecular Science, Graduate School of Science and Forefront Research Center for Fundamental Sciences, Osaka UniversityTomohiroSuzukiKanagawa Technical Center, Yushiro Chemical Industry Co., Ltd.HidenoriShirakawaKanagawa Technical Center, Yushiro Chemical Industry Co., Ltd.YujiroKitamuraKanagawa Technical Center, Yushiro Chemical Industry Co., Ltd.HiroakiTakahashiKanagawa Technical Center, Yushiro Chemical Industry Co., Ltd.YasumasaOhashiKanagawa Technical Center, Yushiro Chemical Industry Co., Ltd.SeijiObataResearch Core for Interdisciplinary Sciences, Okayama UniversityAkiraHaradaSANKEN (The Institute of Scientific and Industrial Research), Osaka UniversityYukaIkemotoJapan Synchrotron Radiation Research InstituteYutaNishinaResearch Core for Interdisciplinary Sciences, Okayama UniversityYasutomoUetsujiDepartment of Mechanical Engineering, Osaka Institute of TechnologyGoMatsubaGraduate School of Organic Materials Engineering, Yamagata UniversityYoshinoriTakashimaDepartment of Macromolecular Science, Graduate School of Science and Forefront Research Center for Fundamental Sciences, Osaka UniversityPractical applications like very thin stress-strain sensors require high strength, stretchability, and conductivity, simultaneously. One of the approaches is improving the toughness of the stress-strain sensing materials. Polymeric materials with movable cross-links in which the polymer chain penetrates the cavity of cyclodextrin (CD) demonstrate enhanced strength and stretchability, simultaneously. We designed two approaches that utilize elastomer nanocomposites with movable cross-links and carbon filler (ketjenblack, KB). One approach is mixing SC (a single movable cross-network material), a linear polymer (poly(ethyl acrylate), PEA), and KB to obtain their composite. The electrical resistance increases proportionally with tensile strain, leading to the application of this composite as a stress- strain sensor. The responses of this material are stable for over 100 loading and unloading cycles. The other approach is a composite made with KB and a movable cross-network elastomer for knitting dissimilar polymers (KP), where movable cross-links connect the CD-modified polystyrene (PSCD) and PEA. The obtained composite acts as a highly sensitive stress-strain sensor that exhibits an exponential increase in resistance with increasing tensile strain due to the polymer dethreading from the CD rings. The designed preparations of highly repeatable or highly responsive stress-strain sensors with good mechanical properties can help broaden their application in electrical devices.No potential conflict of interest relevant to this article was reported.Cell PressActa Medica Okayama2666-1667312022Expression of microbial rhodopsins in Escherichia coli and their extraction and purification using styrene-maleic acid copolymers101046ENKeiichiKojimaGraduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityYukiSudoGraduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityMicrobial rhodopsins are photoreceptive membrane proteins showing various light-dependent biological activities. Styrene-maleic acid (SMA) copolymers spontaneously form nanoscale lipid particles containing membrane proteins and associated lipids without detergent, and can be used to characterize membrane molecules. Here, we provide a protocol to functionally express a thermally stable rhodopsin, Rubrobacter xylanophilus rhodopsin, and an unstable rhodopsin, Halobacterium salinarum sensory rhodopsin I, in Escherichia coli. We then describe the preparation of SMA and the extraction and purification of rhodopsin molecules using SMA. <br>
For complete details on the use and execution of this protocol, please refer to Ueta et al. (2020).No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023裏表紙・英文目次ENNo potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023投稿規程・奥付ENNo potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-3227320232022 年度における「先進病院実習」の取り組み7582ENMizukiMORITAGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama UniversityNaokiKANAYAMAGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama UniversityToshiakiAIDAGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama UniversityToyohikoWATANABEGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama UniversityNoboruYAMASHITAGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama UniversityReiHAKAMADAGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama UniversityYasuyukiYOSHIBAGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University10.18926/interdisciplinary/65468No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023留学生受入れ促進のための英語講義開催7374ENToshihikoKIWAFaculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University10.18926/interdisciplinary/65467No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023岡山大学中央図書館・個人文庫「杏村文庫」の調査：哲学思想を中心に6771ENRyozoSUZUKIGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University10.18926/interdisciplinary/65466No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-32273202320世紀前半における赴日モンゴル人留学生史：内モンゴル医療衛生の近代化におけるホルチンビリクら留学生の位置付けについて6166ENXuefengBAOGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University10.18926/interdisciplinary/65465No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023中国における医療用人工知能発展の歴史的分析：中医学エキスパートシステムを中心に5160ENLingQINGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University10.18926/interdisciplinary/65464This study is based on a historical analysis of the technological development and introduction of artificial intelligence for medical use in China, based on the progress of application of artificial intelligence technology development to the medical field of traditional Chinese medicine and the experience of many experts in clinical practice. Through the application history of Traditional Chinese Medicine（TCM）expert systems technology, we will review its historical characteristics and the necessity of TCM expert system technology. By examining the application cases of TCM expert systems, we can find that Traditional Chinese Medicine（TCM）expert systems play an important role as an auxiliary means of diagnosis and treatment for doctors. This paper finds that the development of Traditional Chinese Medicine（TCM）expert systems is directly related to the change of Chinese government's science and technology policy through the investigation of the application history of Traditional Chinese Medicine（TCM）expert systems. At the same time, because the science and technology policy directly related to the traditional Chinese Medicine（TCM）expert systems appeared late, so the implementation technology of the traditional Chinese Medicine（TCM）expert systems is still insufficient. The technical level adopted in the implementation of the existing traditional Chinese Medicine（TCM）expert systems is still in a relatively low state. Therefore, whether in hardware or software, we should develop a new integrated traditional Chinese Medicine（TCM）expert systems based on the treatment theory of many Traditional Chinese Medicine（TCM）expert systems, so as to meet the needs of modern Traditional Chinese Medicine（TCM）expert systems diagnosis, people's need for healthy life, and medical care. Finally, when studying the historical issues of Traditional Chinese Medicine （TCM）expert systems, the Chinese government's science and technology policy changes are also an integral part.No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023〈迷惑〉意識の類型：『おだやかな死』における〈迷惑〉の用例分析を通じて3949ENNatsumiTANAKAGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University10.18926/interdisciplinary/65463In contemporary Japan, the elderly often say that they do not wish to be a burden on anyone, and they make important decisions with this motivation (here called feelings of "Meiwaku/Burden"). This paper seeks to categorize feelings of "Meiwaku/Burden" according to its relationship to the type of motivation they express. For this purpose, we focused on feelings of "Meiwaku/Burden" of elderly people in France. As there is no easily corresponding phrase in French for our word "Meiwaku/Burden", the French use several different words to express this sense "Meiwaku/Burden". Here we draw examples from Une mort très douce by Simone de Beauvoir, as well as her La Ceremonie des adieux.<br>
The analysis of examples given in these books indicates that "Meiwaku/Burden" of the elderly is motivated by three factors: relationships (déranger), emotions (ennuyer), and body/physical (gêner). In this paper, according to these three motivations we categorize feelings of "Meiwaku/Burden" three types: the feelings of "Meiwaku/Burden" about relationships, the feelings of "Meiwaku/Burden" about emotions, and the feelings of "Meiwaku/Burden" about bodily/physical things.No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023〈迷惑〉意識と自律：スピリチュアルペインとSPBの議論を手がかりに2938ENHarukaHIKASAFaculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University10.18926/interdisciplinary/65462This study aimed to clarify the meaning of feelings of “Meiwaku/Burden” in Japan, which is expressed as “I do not want to bother others” or “I do not want to be a burden.” This is examined specifically in the context of medical care for the terminally and chronically ill. The first section of this paper reviews the core meaning of autonomy and the situations in which feelings of “Meiwaku/Burden” is focused in Japan. Section 2 examines the meaning of “Meiwaku” and “burden,” which is understood in regards to “autonomy,” particularly in the context of patients’ terminal suffering and spiritual pain in palliative care in Japan. Section 3 verifies that “Meiwaku” and “burden” in Japan are sometimes understood as “self-perceived burden (SPB).” Section 4 examines the meaning of “burden” in the discussion of SPB. Section 5 attempts to clarify the meaning of feelings of “Meiwaku/Burden” in medical care, specifically in the context of “autonomy.”No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023相互行為としての〈迷惑〉意識：贈与論的アプローチからの考察1527ENRyozoSUZUKIGraduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University10.18926/interdisciplinary/65461This paper examines elderly people’s Feelings of "Meiwaku / Burden" from the perspective of the act of gift-giving. In Japanese, the word "Morau" is used not only in receiving a concrete object, but also in having something done by someone. Both acts lead to the human relationship and the reciprocity. Both cases can cause a burden on receivers and others. We use then “Sumimasen”. This is not as the same as English words “Thank You”. But this usage of Japanese can be explained from a Gift-giving-theoretic point of view. Because, in terms of the outcome, they are the same thing from this theory. Therefore, we will examine the meaning of the word "receive" based on discussions by Kunio Yanagida, Michizo Toida, Ruth Benedict, Marcel Mauss, and others. We hope to clarify what is elderly people’s Feelings of "Meiwaku / Burden" by analyzing the meaning of human relationships brought about by the act of gift-giving in general.No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023特集にあたって1113ENMasafumiMOTOMURAFaculty of Interdisciplinary Science and Engineering in Health Systems, Okayama UniversityThis special feature is based on the symposium ,"Feelings of "Meiwaku/Burden" in Modern Japan’s Super-aging Society,” which was held on Monday, September 19, 2022. This symposium was sponsored by JSPS KAKENHI Grant Number JP20A00007. This project focuses on the fact that when people think about aging, end-of-life care, and death in modern Japan, many feel that “they do not want to be a burden to others.” The project is divided into three research groups: historic studies, studies of contemporary Japan, and field research. The symposium reported the results of the contemporary Japan research group, which is halfway through its research. The symposium consisted of two sessions, and this special feature is based on the three participants in the session titled “Feelings of"Meiwaku/Burden" : A Comparison with Other Countries.” Ryozo Suzuki’s study focuses on “the giving of gifts as being mutual actions of giving and receiving” to understand the elderly’s feelings of meiwaku and analyzes the significance and complex structures of the feeling of “being a burden to others” at the end of one’s life. Haruka Hikasa’s study considers the feelings of meiwaku in relation to the subject’s autonomy in the context of medical care provided to people with terminal or chronic illnesses. Natsumi Tanaka’s study examines the feelings of meiwaku among the elderly in France and is based on the work of Simone de Beauvoir. She determines the motivations behind the elderly’s feelings of meiwaku and categorizes them. The abovementioned studies present important research results and facilitate future comparative research on the feelings of meiwaku between Japan and other countries.No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023大学院ヘルスシステム統合科学研究科：設置の構想と経緯19ENMasaharuSENOFaculty of Interdisciplinary Science and Engineering in Health Systems, Institute of Academic and Research, Okayama University10.18926/interdisciplinary/65459No potential conflict of interest relevant to this article was reported.岡山大学大学院ヘルスシステム統合科学研究科Acta Medica Okayama2436-322732023表紙・目次ENNo potential conflict of interest relevant to this article was reported.MDPIActa Medica Okayama2409-9279332020Metastasis Model of Cancer Stem Cell-Derived Tumors60ENHagerMansourDepartment of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama UniversityGhmkinHassanLaboratory of Nano-Biotechnology, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama UniversitySaid M.AfifyLaboratory of Nano-Biotechnology, Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama UniversityTingYanDepartment of Pathology, Shanxi Key Laboratory of Carcinogenesis and Translational Research on Esophageal Cancer, Shanxi Medical UniversityAkimasaSenoDepartment of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama UniversityMasaharuSenoDepartment of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama UniversityMetastasis includes the dissemination of cancer cells from a malignant tumor and seed in distant sites inside the body forming secondary tumors. Metastatic cells from the primary tumor can move even before the cancer is detected. Therefore, metastases are responsible for more than 90% of cancer-related deaths. Over recent decades there has been adequate evidence suggesting the existence of CSCs with self-renewing and drug-resistant potency within heterogeneous tumors. Cancer stem cells (CSCs) act as a tumor initiating cells and have roles in tumor retrieve and metastasis. Our group recently developed a unique CSC model from mouse induced pluripotent stem cells cultured in the presence of cancer cell-conditioned medium that mimics tumors microenvironment. Using this model, we demonstrated a new method for studying metastasis by intraperitoneal transplantation of tumors and investigate the metastasis ability of cells from these segments. First of all, CSCs were injected subcutaneously in nude mice. The developed malignant tumors were minimized then transplanted into the peritoneal cavity. Following this, the developed tumor in addition to lung, pancreas and liver were then excised and analyzed. Our method showed the metastatic potential of CSCs with the ability of disseminated and moving to blood circulation and seeding in distant organs such as lung and pancreas. This method could provide a good model to study the mechanisms of metastasis according to CSC theory.No potential conflict of interest relevant to this article was reported.Springer International Publishing AGActa Medica Okayama2523-39633102021Temperature-dependent device properties of gamma-CuI and beta-Ga2O3 heterojunctions796ENRama Venkata KrishnaRaoGraduate School of Natural Science and Technology, Okayama UniversityAjinkya K.RanadeDepartment of Physical Science and Engineering, Nagoya Institute of TechnologyPradeepDesaiDepartment of Physical Science and Engineering, Nagoya Institute of TechnologyGolapKalitaDepartment of Physical Science and Engineering, Nagoya Institute of TechnologyHirooSuzukiGraduate School of Natural Science and Technology, Okayama UniversityYasuhikoHayashiGraduate School of Natural Science and Technology, Okayama UniversityTemperature-dependent studies of Ga2O3-based heterojunction devices are important in understanding its carrier transport mechanism, junction barrier potential, and stability at higher temperatures. In this study, we investigated the temperature-dependent device characteristics of the p-type gamma-copper iodide (gamma-CuI)/n-type beta-gallium oxide (beta-Ga2O3) heterojunctions, thereby revealing their interface properties. The fabricated gamma-CuI/beta-Ga2O3 heterojunction showed excellent diode characteristics with a high rectification ratio and low reverse saturation current at 298 K in the presence of a large barrier height (0.632 eV). The temperature-dependent device characteristics were studied in the temperature range 273-473 K to investigate the heterojunction interface. With an increase in temperature, a gradual decrease in the ideality factor and an increase in the barrier height were observed, indicating barrier inhomogeneity at the heterojunction interface. Furthermore, the current-voltage measurement showed electrical hysteresis for the reverse saturation current, although it was not observed for the forward bias current. The presence of electrical hysteresis for the reverse saturation current and of the barrier inhomogeneity in the temperature-dependent characteristics indicates the presence of some level of interface states for the gamma-CuI/beta-Ga2O3 heterojunction device. Thus, our study showed that the electrical hysteresis can be correlated with temperature-dependent electrical characteristics of the beta-Ga2O3-based heterojunction device, which signifies the presence of surface defects and interface states.No potential conflict of interest relevant to this article was reported.WileyActa Medica Okayama2398-8835312019Evaluation of a point-of-care serum creatinine measurement device and the impact on diagnosis of acute kidney injury in pediatric cardiac patients: A retrospective, single center studye143ENSatoshiKimuraDepartment of Anesthesiology and Resuscitation, Okayama University HospitalTatsuoIwasakiDepartment of Anesthesiology and Resuscitation, Okayama University HospitalKazuyoshiShimizuDepartment of Anesthesiology and Resuscitation, Okayama University HospitalTomoyukiKanazawaDepartment of Anesthesiology and Resuscitation, Okayama University HospitalHirokazuKawaseDepartment of Anesthesiology and Resuscitation, Okayama University HospitalNaohiroShiojiDepartment of Anesthesiology and Resuscitation, Okayama University HospitalYasutoshiKuroeDepartment of Anesthesiology and Resuscitation, Okayama University HospitalSatoshiIsoyamaDepartment of Anesthesiology and Resuscitation, Okayama University HospitalHiroshiMorimatsuDepartment of Anesthesiology and Resuscitation, Okayama University HospitalBackground and aims: Agreement between measurements of creatinine concentrations using point-of-care (POC) devices and measurements conducted in a standard central laboratory is unclear for pediatric patients. Our objectives were (a) to assess the agreement for pediatric patients and (b) to compare the incidence of postoperative acute kidney injury (AKI) according to the two methods. <br>
Methods: This retrospective, single-center study included patients under 18 years of age who underwent cardiac surgery and who were admitted into the pediatric intensive care unit of a tertiary teaching hospital (Okayama University Hospital, Japan) from 2013 to 2017. The primary objective was to assess the correlation and the agreement between measurements of creatinine concentrations by a Radiometer blood gas analyzer (Cre(gas)) and those conducted in a central laboratory (Cre(lab)). The secondary objective was to compare the incidence of postoperative AKI between the two methods based on Kidney Disease Improving Global Outcomes (KDIGO) criteria. <br>
Results: We analyzed the results of 1404 paired creatinine measurements from 498 patients, whose median age was 14 months old (interquartile range [IQR] 3, 49). The Pearson correlation coefficient of Cre(gas) vs Cre(lab) was 0.968 (95% confidence interval [CI], 0.965-0.972, P < 0.001). The median bias between Cre(gas) and Cre(lab) was 0.02 (IQR -0.02, 0.05) mg/dL. While 199 patients (40.0%) were diagnosed as having postoperative AKI based on Cre(lab), 357 patients (71.7%) were diagnosed as having postoperative AKI based on Cre(gas) (Kappa = 0.39, 95% CI, 0.33-0.46). In a subgroup analysis of patients whose Cre(gas) and Cre(lab) were measured within 1 hour, similar percentage of patients were diagnosed as having postoperative AKI based on Cre(gas) and Cre(lab) (42.8% vs 46.0%; Kappa = 0.76, 95% CI, 0.68-0.84). <br>
Conclusion: There was an excellent correlation between Cre(gas) and Cre(lab) in pediatric patients. Although more patients were diagnosed as having postoperative AKI based on Cre(gas) than based on Cre(lab), paired measurements with a short time gap showed good agreement on AKI diagnosis.No potential conflict of interest relevant to this article was reported.MDPIActa Medica Okayama2571-841X322020Secretory Carcinoma of Salivary Gland with High-Grade Histology Arising in Hard Palate: A Case Report6ENKiyofumiTakabatakeDepartment of Oral Pathology and Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityKeisukeNakanoDepartment of Oral Pathology and Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityHotakaKawaiDepartment of Oral Pathology and Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversitySaoriYoshidaDepartment of Oral Pathology and Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityHarukaOmoriDepartment of Oral Pathology and Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityMay WathoneOoDepartment of Oral Pathology and Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityShanQiushengDepartment of Oral Pathology and Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityKenichiroUchidaDepartment of Oral and Maxillofacial Surgery, Yamaguchi University Graduate School of MedicineKatsuakiMishimaDepartment of Oral and Maxillofacial Surgery, Yamaguchi University Graduate School of MedicineHitoshiNagatsukaDepartment of Oral Pathology and Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversitySecretory carcinoma (SC) is a recently described salivary gland tumor reported in the fourth edition of World Health Organization classification of head and neck tumors. SC is characterized by strong S-100 protein, mammaglobin, and vimentin immunoexpression, and harbors a t(12;15)(p13;q25) translocation which leads to ETV6-NTRK3 fusion product. Histologically, SC displays a lobulated growth pattern and is often composed of microcystic, tubular, and solid structures with abundant eosinophilic homogenous or bubbly secretion. SC is generally recognized as low-grade malignancy with low-grade histopathologic features, and metastasis is relatively uncommon. In this case, we described a SC of hard palate that underwent high grade transformation and metastasis to the cervical lymph node in a 54-year-old patient. In addition, this case showed different histological findings between primary lesion and metastasis lesion. Therefore, the diagnosis was confirmed by the presence of ETV6 translocation. Here, we report a case that occurred SC with high-grade transformation in the palate, and a review of the relevant literature is also presented.No potential conflict of interest relevant to this article was reported.IOP Publishing LtdActa Medica Okayama2515-7655332021Simulating the redox potentials of unexplored phenazine derivatives as electron mediators for biofuel cells034008ENRyoNakagawaGraduate School of Natural Science and Technology, Okayama UniversityYutaNishinaGraduate School of Natural Science and Technology, Okayama UniversityIn this research, we aimed to establish a guideline for designing electron mediators suitable for biofuel cells. A redox potential simulator was fabricated by combining density functional theory calculation and experiment, allowing us to select molecules with appropriate redox potentials efficiently. Previously, mediators have been developed depending on the trials and errors; thus, our strategy will speed up the development of biofuel cells with outstanding performances.No potential conflict of interest relevant to this article was reported. NatureActa Medica Okayama2399-3650312020Localized-to-itinerant transition preceding antiferromagnetic quantum critical point and gapless superconductivity in CeRh0.5Ir0.5In5148ENShinjiKawasakiDepartment of Physics, Okayama UniversityToshihideOkaDepartment of Physics, Okayama UniversityAkiraSorimeDepartment of Physics, Okayama UniversityYujiKogameDepartment of Physics, Okayama UniversityKazuhiroUemotoDepartment of Physics, Okayama UniversityKazuakiMatanoDepartment of Physics, Okayama UniversityJingGuoInstitute of Physics, Chinese Academy of Sciences, Beijing National Laboratory for Condensed Matter PhysicsShuCaiInstitute of Physics, Chinese Academy of Sciences, Beijing National Laboratory for Condensed Matter PhysicsLilingSunInstitute of Physics, Chinese Academy of Sciences, Beijing National Laboratory for Condensed Matter PhysicsJohn L.SarraoLos Alamos National LaboratoryJoe D.ThompsonLos Alamos National LaboratoryGuo-QingZhengDepartment of Physics, Okayama UniversityA fundamental problem posed from the study of correlated electron compounds, of which heavy-fermion systems are prototypes, is the need to understand the physics of states near a quantum critical point (QCP). At a QCP, magnetic order is suppressed continuously to zero temperature and unconventional superconductivity often appears. Here, we report pressure T-c. (P)-dependent In-115 nuclear quadrupole resonance (NQR) measurements on heavy-fermion antiferromagnet CeRh0.5Ir0.5In5. These experiments reveal an antiferromagnetic (AF) QCP at P-c(AF) = 1.2 GPa where a dome of superconductivity reaches a maximum transition temperature Tc. Preceding P-c(AF), however, the NQR frequency nu(Q) undergoes an abrupt increase at P-c* = 0.8 GPa in the zero-temperature limit, indicating a change from localized to itinerant character of cerium's f-electron and associated small-to-large change in the Fermi surface. At P-c(AF) where T-c is optimized, there is an unusually large fraction of gapless excitations well below T-c that implicates spin-singlet, odd-frequency pairing symmetry.No potential conflict of interest relevant to this article was reported.ElsevierActa Medica Okayama2666250732020Bilateral segmental lung transplantation for children: Transplantation using split adult living-donor lower lobe311314ENTakahiroOtoTransplant Center, Okayama University HospitalYukikoHikasaAnesthesiology and Resuscitology, Okayama University HospitalAkikazuHagiyamaPhysical Medicine and Rehabilitation, Okayama University HospitalMotomuKobayashiAnesthesiology and Resuscitology, Okayama University HospitalNo potential conflict of interest relevant to this article was reported.Nature Acta Medica Okayama2399-3642312020Structure of a cyanobacterial photosystem I surrounded by octadecameric IsiA antenna proteins232ENFusamichiAkitaGraduate School of Natural Science and Technology, Okayama UniversityRyoNagaoResearch Institute for Interdisciplinary Science, Okayama UniversityKojiKatoResearch Institute for Interdisciplinary Science, Okayama UniversityYoshikiNakajimaGraduate School of Natural Science and Technology, Okayama UniversityMakioYokonoNippon Flour Mills Co., Ltd., Innovation CenterYoshifumiUenoGraduate School of Science, Kobe UniversityTakehiroSuzukiBiomolecular Characterization Unit, RIKEN Center for Sustainable Resource ScienceNaoshiDohmaeBiomolecular Characterization Unit, RIKEN Center for Sustainable Resource ScienceJian-RenShen Research Institute for Interdisciplinary Science and Graduate School of Natural Science and Technology, Okayama UniversitySeijiAkimotoGraduate School of Science, Kobe UniversityNaoyukiMiyazakiLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of TsukubaIron-stress induced protein A (IsiA) is a chlorophyll-binding membrane-spanning protein in photosynthetic prokaryote cyanobacteria, and is associated with photosystem I (PSI) trimer cores, but its structural and functional significance in light harvesting remains unclear. Here we report a 2.7-angstrom resolution cryo-electron microscopic structure of a supercomplex between PSI core trimer and IsiA from a thermophilic cyanobacterium Thermosynechococcus vulcanus. The structure showed that 18 IsiA subunits form a closed ring surrounding a PSI trimer core. Detailed arrangement of pigments within the supercomplex, as well as molecular interactions between PSI and IsiA and among IsiAs, were resolved. Time-resolved fluorescence spectra of the PSI-IsiA supercomplex showed clear excitation-energy transfer from IsiA to PSI, strongly indicating that IsiA functions as an energy donor, but not an energy quencher, in the supercomplex. These structural and spectroscopic findings provide important insights into the excitation-energy-transfer and subunit assembly mechanisms in the PSI-IsiA supercomplex. Akita et al. present the latest approach to solve IsiA-PSI supercomplex molecular structure with increased resolution using cryo-EM and time-resolved fluorescence studies. With 2.7 angstrom resolution, they reveal molecular interactions between PSI and IsiA subunits and that IsiA functions as an energy donor in the supercomplex. No potential conflict of interest relevant to this article was reported.WoleyActa Medica Okayama2475-0328312018Multicenter retrospective study to evaluate the efficacy and safety of the double-flap technique as antireflux esophagogastrostomy after proximal gastrectomy (rD-FLAP Study)96103ENShinjiKurodaDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesYasuhiroChodaDepartment of Surgery, Hiroshima City Hiroshima Citizens HospitalShinyaOtsukaDepartment of Surgery, Fukuyama Medical CenterSatoshiUeyamaDepartment of Surgery, Mihara Red Cross HospitalNorimitsuTanakaDepartment of Surgery, Kagawa Prefectural Center HospitalAtsushiMuraokaDepartment of Surgery, Kagawa Rosai HospitalShinjiHatoDepartment of Surgery, Shikoku Cancer CenterToshikazuKimuraDepartment of Surgery, Okayama Saiseikai General Hospital,KohjiTanakayaDepartment of Surgery, Iwakuni Clinical CenterSatoruKikuchiDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesShunsukeTanabeDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesKazuhiroNomaDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesMasahikoNishizakiDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesShunsukeKagawaDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesYasuhiroShirakawaDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesYasuakiKamikawaDepartment of Surgery, Matsuda HospitalToshiyoshiFujiwaraDepartment of Gastroenterological Surgery Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesAIM:
As a result of the difficulty in effective prevention of gastroesophageal reflux, no standard reconstruction procedure after proximal gastrectomy (PG) has yet been established. The double-flap technique (DFT), or Kamikawa procedure, is an antireflux reconstruction procedure in esophagogastrostomy. The efficacy of DFT has recently been reported in several studies. However, these were all single-center studies with a limited number of cases.<br/>
METHODS:<br/>
We conducted a multicenter retrospective study in which patients who underwent DFT, irrespective of disease type and reconstruction approach, at each participating institution between 1996 and 2015 were registered. Primary endpoint was incidence of reflux esophagitis at 1-year after surgery, and secondary endpoint was incidence of anastomosis-related complications.<br/>
RESULTS:<br/>
Of 546 patients who were eligible for this study, 464 patients who had endoscopic examination at 1-year follow up were evaluated for reflux esophagitis. Incidence of reflux esophagitis of all grades was 10.6% and that of grade B or higher was 6.0%. Male gender and anastomosis located in the mediastinum/intra-thorax were independent risk factors for grade B or higher reflux esophagitis (odds ratio [OR]: 4.21, 95% confidence interval [CI]: 1.44-10.9, P = 0.0109). Total incidence of anastomosis-related complications was 7.2%, including leakage in 1.5%, strictures in 5.5% and bleeding in 0.6% of cases. Laparoscopic reconstruction was the only independent risk factor for anastomosis-related complications (OR: 3.93, 95% CI: 1.93-7.80, P = 0.0003).<br/>
CONCLUSION:<br/>
Double-flap technique might be a feasible option after PG for effective prevention of reflux, although anastomotic stricture is a complication that must be well-prepared for.No potential conflict of interest relevant to this article was reported.John Wiley & SonsActa Medica Okayama24750328342019Multidisciplinary oncolytic virotherapy for gastrointestinal cancer396404ENToshiyoshiFujiwara Department of Gastroenterological Surgery Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical SciencesReplication-selective tumor-specific viruses represent a novel approach for treating neoplastic diseases. These vectors are designed to induce virus-mediated lysis of tumor cells after selective intracellular virus propagation. For targeting cancer cells, the use of tissue- or cell-specific promoters that are expressed in diverse tumor types but silent in normal cells is required. Human telomerase is highly active in more than 85% of primary cancers, regardless of tissue origin, and its activity is closely correlated with human telomerase reverse transcriptase (hTERT) expression. We constructed an attenuated adenovirus 5 vector (telomelysin, OBP-301) in which the hTERT promoter element drives expression of E1 genes. As only tumor cells that express the telomerase can activate this promoter, the hTERT proximal promoter allows for preferential expression of viral genes in tumor cells, leading to selective viral replication and oncolytic cell death. Upon US Food and Drug Administration approval, a phase 1 dose-escalation study of intratumoral injection of telomelysin for various solid tumors has been completed to confirm the safety, tolerability, and feasibility of the agent. Moreover, we found that adenoviral E1B 55-kDa protein in telomelysin inhibits the radiation-induced DNA repair machinery. Thus, tumor cells infected with telomelysin could be rendered sensitive to ionizing radiation. Recently, we assessed the safety and efficacy of intratumoral injection of telomelysin with radiotherapy in esophageal cancer patients not suited for standard treatments. This review highlights some very promising clinical advances in cancer therapeutic technologies using telomerase-specific oncolytic virotherapy.No potential conflict of interest relevant to this article was reported.Royal Society of ChemistryActa Medica Okayama204620693312013Effects of hydrophobic hydration on polymer chains immersed in supercooled water1274312750ENTomonariSumiDepartment of Chemistry, Okayama UniversityHideoSekinoDepartment of Computer Science and Engineering, Toyohashi University of Technology A multiscale simulation of a hydrophobic polymer chain immersed in water including the supercooled region is presented. Solvent effects on the polymer conformation were taken into account via liquid–state density functional theory in which a free-energy functional model was constructed using a density response function of bulk water, determined from a molecular dynamics (MD) simulation. This approach overcomes sampling problems in simulations of high-viscosity polymer solutions in the deeply supercooled region. Isobars determined from the MD simulations of 4000 water molecules suggest a liquid–liquid transition in the deeply supercooled region. The multiscale simulation reveals that a hydrophobic polymer chain exhibits swelling upon cooling along isobars below a hypothesized second critical pressure; no remarkable swelling is observed at higher pressures. These observations agree with the behavior of a polymer chain in a Jagla solvent model that qualitatively reproduces the thermodynamics and dynamics of liquid water. A theoretical analysis of the results obtained from the multiscale simulation show that a decrease in entropy due to the swelling arises from the formation of a tetrahedral hydrogen bond network in the hydration shell.No potential conflict of interest relevant to this article was reported.SCIENCEDOMAIN internationalActa Medica Okayama22310886322013Multi-locus Genotyping Reveals High Occurrence of Mixed Assemblages in Giardia duodenalis within a Limited Geographical Boundary190197ENAvik KumarMukherjeeDepartment of Parasitology, National Institute of Cholera and Enteric DiseasesSumallyaKarmakarDepartment of Parasitology, National Institute of Cholera and Enteric DiseasesDibyenduRajDepartment of Parasitology, National Institute of Cholera and Enteric DiseasesSandipanGangulyDepartment of Parasitology, National Institute of Cholera and Enteric DiseasesAim: To determine the common genotypes of Giardia duodenalis causing diarrhea in the study region and to assess the extent of genetic polymorphism among them.
Study Design: Stool samples were collected from the patients attending IDBG Hospital, Kolkata with diarrheal complaints through a systemic sampling technique and were screened for Giardia duodenalis. The G. duodenalis positive samples were subjected to molecular genotyping through ‘PCR - Direct DNA sequencing’ procedure. All the sequence data obtained were incorporated into MEGA 4 software for multiple alignment and validation followed by phylogenetic analysis. The genotyping data obtained are stored in Excel spreadsheets and incorporated into EpiInfo 3.1 for analyzing possible association of genotype outcome with common physical factors such as age, sex etc.
Place and Duration of Study: Department of parasitology, National Institute of Cholera and Enteric Diseases, Kolkata, India from July 2009 to November 2011.
Methodology: A total of 68 Giardia duodenalis positive stool samples were identified from the diarrhea patients attending IDBG hospital in the city and were subjected to multi-locus genotyping. Fragments of ß-giardin, Glutamate-dehydrogenase and Triosephosphate-isomerase genes of Giardia were amplified from those samples with specific primers and sequenced. All the sequences were analyzed using MEGA 4 software for obtaining the genotyping results.
Results: Multi-locus genotyping identified 13 isolates as assemblage A and 41 as assemblage B, whereas 14 of them could not be assigned in a particular group. Detailed phylogenetic analysis revealed that multiple genotypes were observed in those 14 isolates depending upon the marker loci.
Conclusion: The study could produce a preliminary idea about the G. duodenalis genotypes found in Kolkata city. High percentage of mixed assemblages in the study population also revealed the presence of genetic diversity among a small population of diarrheal patient within a limited geographical boundary. It has also hypothesized the possibility of inter-assemblage genetic exchange among Giardia.No potential conflict of interest relevant to this article was reported.Wiley-BlackwellActa Medica Okayama20458827322014Isolation of viable but nonculturable Vibrio cholerae O1 from environmental water samples in Kolkata, India, in a culturable state239246ENMitsutoshiSenohCollaborative Research Center of Okayama University for Infectious Diseases in India, Okayama UniversityJayeetaGhosh-BanerjeeNational Institute of Cholera and Enteric Diseases,TamakiMizunoCollaborative Research Center of Okayama University for Infectious Diseases in India, Okayama UniversitySumioShinodaCollaborative Research Center of Okayama University for Infectious Diseases in India, Okayama UniversityShin-ichiMiyoshiGraduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama UniversityTakashiHamabataResearch Institute, National Center for Global Health and MedicineG. BalakrishNairTranslational Health Science and Technology InstituteYoshifumiTakedaCollaborative Research Center of Okayama University for Infectious Diseases in India, Okayama University Previously, we reported that viable but nonculturable (VBNC) Vibrio cholerae was converted into a culturable state by coculture with several eukaryotic cell lines including HT-29 cells. In this study, we found that a factor converting VBNC V. cholerae into a culturable state (FCVC) existed in cell extracts of eukaryotic cells. FCVC was nondialyzable, proteinase K-sensitive, and stable to heating at <60°C for 5 min. We prepared thiosulfate citrate bile salts sucrose (TCBS) plates with FCVC (F-TCBS plates). After confirming that VBNC V. cholerae O1 and O139 formed typical yellow colonies on F-TCBS plates, we tried to isolate cholera toxin gene-positive VBNC V. cholerae from environmental water samples collected in urban slum areas of Kolkata, India and succeeded in isolating V. cholerae O1 El Tor variant strains harboring a gene for the cholera toxin. The possible importance of VBNC V. cholerae O1 as a source of cholera outbreaks is discussed.No potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-966532018裏表紙・英文目次 ENNo potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-966532018奥付ENNo potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-966532018キャリア教育における多元的自己評価試論V : 2017 年度の評価結果から8594ENYoshikazuNakayama10.18926/56592 岡山大学で開講しているキャリア教育関連授業科目の中で、2 つの授業科目を選定して2016 年度第 4 学期に多元的自己評価測定を行い、その結果からキャリア教育における教育効果測定には、多元的自己評価が有効であるという検証を試みた。
この多元的自己評価を活用して、2017 年度にも同じ 2 つの授業科目へ同様の教育効果測定に取り組むことができた。そこで、2016 年度と 2017 年度の年度間比較を行い、当該授業科目の教育効果を明らかにするとともに、年度間比較によって見えてきた課題と今後の改善点についても検討した。
その結果、授業科目の基盤となるカリキュラムの確立が安定的な教育効果を生み出すとともに、年度ごとに変化する教育内容及び教育方法、受講生の属性の違いなどがもたらす教育効果の差異を見出すことができ、今後の改善につなげることが可能となった。また、多元的自己評価そのものについても成果と課題について検討した。No potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-966532018Some Thoughts on Designing a Global Studies Curriculum for a Japanese University7184ENDong KwangKim10.18926/56591 This paper sketches an undergraduate global studies program for a Japanese university. It first examines the context of the developing notions of global education and its current status. It then examines the appropriateness of the curriculum for global human resources development at Japanese universities, which passes widely as global education in Japan. It then shows why a new global studies program may be necessary by exposing the contradictions inherent in the programs of global human resources development taken as global education. The paper concludes by proposing a global studies curriculum to implement on the lower division level of a Japanese university.No potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-966532018海外研修における参加促進要因に関する考察5170ENTakaoInamori10.18926/56590 本研究は、平成27 年度夏期から平成30 年度夏期に実施した短期海外研修の参加者に対して行ったアンケート（回答者625 名、回答率67％）をもとに、参加促進要因を明らかにしようと試みたものである。分析から明らかになった海外研修参加を促すポイントは、三点である。一つ目は「早い時期の動機づけ」。二つ目は「学生のニーズに合ったプログラムづくり」。三つ目は「保護者に対する留学に関する説明」の必要性である。特に三つ目に関し、女子学生の強い海外志向が確認されたものの、男子学生と比較し「保護者の理解」、「経済的負担」、「就職活動の遅れ」といった点において、不安を抱えている女子学生が多いことが明らかになった。No potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-966532018岡山大学桑の木留学生宿舎の実態と課題 : 留学生宿舎を教育資源として活用するために3150ENMarikoUzukaInstitute for Education and Student Services, Okayama UniversityMasumiOkaMasumiFujimotoInstitute for Education and Student Services, Okayama University10.18926/56589 スーパーグローバル大学の指標の一つに受入留学生数の増加が掲げられているが、留学生受入に不可欠な留学生寮の整備は、以前からの長年の課題であった。安心して留学生活を送るための基盤でもある寮の管理・運営は、毎日の生活と密接な関係があり、文化背景や言語が異なる学生が共同生活を営む寮では、大小様々なトラブルがつきものである。
この状況を少しでも改善するため、岡山学では2014 年にレジデントアシスタント（RA）制度の導入を皮切りに、日本人学生との混住化を推進してきた。従来の留学生支援という観点にとどまらず、１）「一住人」から自治意識をもった寮生への成長、２）留学生、日本人学生双方の日本・日本文化・異文化理解の促進、という教育的要素を加えた新しい国際寮の在り方を模索してきたといえる。その結果、支援の充実や教育的効果も見られた一方で、教育資源として寮を活用するには管理・運営だけではなく、積極的な学生指導の姿勢が肝要であることが分かった。混住化から4 年経ち、導入初期の段階を終えた岡山大学では新たな局面を迎えている。No potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-966532018中学生のネガティブ感情に関連する学校ストレス感受性項目の収集と分類1730ENChikaraMiyaji10.18926/56588 ストレス感受性は，ネガティブな環境刺激に応じてネガティブ感情を経験する傾向のことである。本研究の目的は，学校生活場面に焦点をあて，学校ストレス感受性に関連する出来事（場面）を収集してネガティブ感情との関連から分類することである。公立中学校１年生31名（男子17名，女子14名）を対象に，代表的なネガティブ感情を具体的に提示したうえで，学校ストレス感受性に関連する出来事（場面）について自由記述による回答を求めた。KJ法を援用し，コレスポンデンス分析およびクラスター分析の結果，19の小カテゴリーは「イライラ・怒り群」「落ち込み・悲しみ群」「恥・緊張群」「不安・恐怖群」の４つの群に分類された。今後，この分類に適合する項目を準備し，尺度を作成していく必要がある。No potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-9665320181906年刊『韓語』の韓国語について716ENNamtaekJin10.18926/56587 本稿では1906年に日本人のための朝鮮語学習書として、日本に亡命していた韓国人の安永中(1870年〜1910年)により松雲堂で発行された『韓語』に現れる韓国語を分析し、開化期の韓国語の特徴を概観した。著者は卷頭の「例言」で、本書は専ら日本人の朝鮮語学習のために古籍や自分の研究等により編纂し、日本語文法に依ることと、用言の活用のように変化の多い用法の習得に重点をおき、会話文も重視していることを示している。本書は誤字も少なく、開化期の識者層の韓国語をよく反映している点で開化期の韓国語の資料として価値をもつといえる。今後、明治期の他の朝鮮語学習書や韓国人のための日本語学習書を考察することで、現代韓国語の形成過程をより明らかにできると期待される。No potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-966532018教員を対象とした「授業スタイルアンケート」に基づくアクティブラーニング実施率の評価16ENYujiKobayashi10.18926/56586 授業におけるアクティブラーニングの実施度合いを測定するうえで、学生が実際にアクティブラーニングを実現できたかを測ることは極めて難しい。岡山大学では、教員に対して授業実施内容に関するアンケート（授業スタイルアンケート）を行い、その結果によりアクティブラーニング実施率を調査する試みが行われた。本稿では、この「授業スタイルアンケート」の実施概要とその分析結果について報告する。No potential conflict of interest relevant to this article was reported.岡山大学全学教育・ 学生支援機構Acta Medica Okayama2432-966532018表紙・目次ENNo potential conflict of interest relevant to this article was reported.Acta Medica Okayama24156698312018A Test Code Generation Method for Coding Standard Input/Output with Exception Handling in Java Programming Learning Assistant System3037ENEi Ei MonOkayama University, Department of Electrical and Communication EngineeringNobuoFunabikiOkayama University, Department of Electrical and Communication EngineeringRyotaKusakaOkayama University, Department of Electrical and Communication EngineeringKhin Khin ZawOkayama University, Department of Electrical and Communication EngineeringWen-ChungKaoNational Taiwan Normal University, Department of Electrical Engineering To advance Java programming educations, we have developed the Java Programming Learning Assistant System (JPLAS) that provides the code writing problem. This problem asks a student to write a source code to satisfy the specification of a given assignment, where the correctness is verified by running test code on JUnit. For a novice student, a code of implementing the standard input/output with the exception handling should be mastered at the early stage as the first step programming for human interfaces. However, for a teacher, it is not easy to write the test code for it. In this paper, we propose a test code generation method to generate the test code using the reference source code for the assignment. In the evaluation of this proposal, all the students completed the codes using the generated test codes for exception handling, although the use of exception handling functions was sometimes insufficient or incorrect.
No potential conflict of interest relevant to this article was reported.Okayama UniversityActa Medica Okayama32014Organ regeneration research leaps forwardENShinjiKitamuraNo potential conflict of interest relevant to this article was reported.the American Society for MicrobiologyActa Medica Okayama2169-8287342015Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces the Nucleoside Antibiotic Sinefungine00715-15e00715-15ENKenshiroOshimaMasahiraHattoriHitomiShimizuKojiFukudaMichikoNemotoKenjiInagakiTakashiTamuraA draft genome sequence of Streptomyces incarnatus NRRL8089, which produces the nucleoside antibiotic sinefungin, is described here. The genome contains 8,897,465 bp in 76 contigs and 8,266 predicted genes. Interestingly, the genome encodes an open reading frame for selenocysteine-containing formate dehydrogenase-O and the selenoprotein biosynthetic gene cluster selABCD.No potential conflict of interest relevant to this article was reported.Springer International PublishingActa Medica Okayama2193-180132014Glass transition temperature of dried lens tissue pretreated with trehalose, maltose, or cyclic tetrasaccharide317ENTetsuhiroKawataToshihikoMatsuoTetsuyaUchida[PURPOSE]
Glass transition temperature is a main indicator for amorphous polymers and biological macromolecules as materials, and would be a key for understanding the role of trehalose in protecting proteins and cells against desiccation. In this study, we measured the glass transition temperature by differential scanning calorimetry of dried lens tissues as a model of a whole biological tissue to know the effect of pretreatment by trehalose and other sugars.
[METHODS]
Isolated porcine lenses were incubated with saline, 100 or 1000 mM concentration of trehalose, maltose, or cyclic tetrasaccharide dissolved in saline at room temperature for 150 minutes. The solutions were removed and all samples were dried at room temperature in a desiccator until no weight change. The dried tissues were ground into powder and placed in a measuring pan for differential scanning calorimetry.
[RESULTS]
The glass transition temperature of the dried lens tissues, as a mean and standard deviation, was 63.0 ± 6.4°C (n = 3) with saline pretreatment; 53.0 ± 0.8°C and 56.3 ± 2.7°C (n = 3), respectively, with 100 and 1000 mM trehalose pretreatment; 56.0 ± 1.6°C and 55.8 ± 1.1°C (n = 3), respectively, with 100 and 1000 mM maltose pretreatment; 60.0 ± 8.8°C and 59.2 ± 6.3°C (n = 3), respectively, with 100 and 1000 mM cyclic tetrasaccharide pretreatment. The glass transition temperature appeared lower, although not significantly, with trehalose and maltose pretreatments than with saline and cyclic tetrasaccharide pretreatments (P > 0.05, Kruskal-Wallis test). The glass transition temperature of the dried lens tissues with trehalose pretreatment appeared more noticeable on the thermogram, compared with other pretreatments.
[CONCLUSIONS]
The glass transition temperature was measured for the first time in the dried lens tissues as an example of a whole biological tissue and might provide a basis for tissue preservation in the dried condition.No potential conflict of interest relevant to this article was reported.Springer International PublishingActa Medica Okayama2193-180132014Intraocular lens implantation in unilateral congenital cataract with minimal levels of persistent fetal vasculature in the first 18 months of life361ENToshihikoMatsuo[PURPOSE]
To describe the incidence of unilateral congenital cataract associated with minimal (ultrasonically undetectable) levels of persistent fetal vasculature in the first 18 months of the life and to report surgical methods for intraocular lens implantation, using 25-gauge vitrectomy system.
[METHODS]
Retrospective review was made on 16 consecutive patients with bilateral or unilateral congenital cataract in the first 18 months of the life who underwent surgery at Okayama University Hospital after the introduction of the 25-gauge vitrectomy system from October 2005 to March 2013. As the standard of care at this hospital in the study period, intraocular lenses were not implanted in children with bilateral cataract while intraocular lenses were implanted in those with unilateral cataract.
[RESULTS]
Ten children with bilateral cataract underwent lensectomy in both eyes with a 25-gauge vitreous cutter under irrigation with a 25-gauge infusion cannula, inserted from two side ports at the corneal limbus. Six children with unilateral cataract underwent intraocular lens implantation and posterior capsulotomy after lens aspiration from limbal side ports. No patient showed vitreous abnormalities on ultrasound examinations before the surgery. At the surgery, all 10 children with bilateral cataract showed no additional abnormalities. In contrast, 3 children with unilateral cataract at the age younger than 12 months showed white fibrous tissue in the anterior vitreous integrated with the posterior lens capsule while the other 3 children with unilateral cataract at the age from 12 to 18 months did not have vitreous abnormalities. The fibrous tissue was cut together in the process of posterior capsulotomy from a 25-gauge trocar inserted at 1.5 mm posterior from the corneal limbus.
[CONCLUSIONS]
Unilateral congenital cataract in the first 12 months of the life has a high incidence for the association with anterior type of persistent fetal vasculature which could not be detected by preoperative ultrasound examinations. Intraocular lens implantation was technically feasible in unilateral cataract with or without minimal levels of persistent fetal vasculature in the first 18 months of the life.No potential conflict of interest relevant to this article was reported.岡山大学資源生物科学研究所Acta Medica Okayama0918-510031996資源生物科学研究所年報No.3ENNo potential conflict of interest relevant to this article was reported.岡山大学教育学部社会科研究室Acta Medica Okayama3瀬戸内農村の生産と社会構造 : 岡山県淺口郡船穂町の場合ENNo potential conflict of interest relevant to this article was reported.Acta Medica Okayama2045-232232013Electric double-layer capacitance between an ionic liquid and few-layer grapheneENEriUesugiHidenoriGotoRitsukoEguchiAkihikoFujiwaraYoshihiroKubozonoIonic-liquid gates have a high carrier density due to their atomically thin electric double layer (EDL) and extremely large geometrical capacitance C-g. However, a high carrier density in graphene has not been achieved even with ionic-liquid gates because the EDL capacitance C-EDL between the ionic liquid and graphene involves the series connection of C-g and the quantum capacitance C-q, which is proportional to the density of states. We investigated the variables that determine C-EDL at the molecular level by varying the number of graphene layers n and thereby optimising C-q. The C-EDL value is governed by C-q at n, 4, and by C-g at n > 4. This transition with n indicates a composite nature for C-EDL. Our finding clarifies a universal principle that determines capacitance on a microscopic scale, and provides nanotechnological perspectives on charge accumulation and energy storage using an ultimately thin capacitor.No potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996奥付ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996岡山大学算数・数学教育学会誌規定9999ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996岡山大学算数・数学教育学会会則9898ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996学会だより9397ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996フラクタル幾何学への誘い ―複素力学系とその一般化―8992ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996大学生の試験成績と数学に対する意識との関連について7787ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996Number Field Sieveによる素因数分解とその計算機実験6975ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996微分の導入にグラフ電卓を用いる接線のイメージ調査と曲線を調べる活動5968ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996集合族の組合せ論とその教材化に関する研究4758ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996数学教育におけるインターネットの活用に関する実験的研究 ―MATH-CUT STUDIUM―3746ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996動的に図形をとらえる教材の開発 ―対話型図形学習ソフトを用いて2536ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996数学的な見方や考え方を高める課題学習 ―コンピュータの活用を通して―1724ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996自ら学ぶ意欲を育てる指導のあり方(その3) ―6年「貿料の調べ方」の指導を通して―1115ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996「原理・法則を活用する力」を育てる授業 ―第3学年「かけ算(2)」の指導を通して―79ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-31553199610の合成・分解の理解と習熟を図るための十面体のサイコロの効果的な使い方15ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996巻頭言 生涯学習時代雑感ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996目次ENNo potential conflict of interest relevant to this article was reported.岡山大学算数・数学教育学会Acta Medica Okayama1341-315531996表紙ENNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama311925Über die Erhaltung der Keimkraft von Sämereien und über Trocknungsmittel.147151ENMantarōKondōNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama311925Über die Einwirkung des Kalks auf die Erhaltung der Keimkraft von Sämereien.135146ENMantarōKondōNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama311925Über die Dauer der Erhaltung der Keimkraft bei verschiedenen Samenarten in Japan.127133ENMantarōKondōNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama311925Kreuzungsuntersuchungen an Reispflanzen. I Genetische Analyse der Granne, der Spelzenfarbe und der Endospermbeschaffenheit bei einigen Sorten des Reises.1126ENYasukeYamaguchiNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama351928Studies on Bacterial Catalase.505528ENAraoItanoSatiyoArakawaNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama351927Some Scientific Consideration on the Itano Process of Composting.* I. General Description, Nature of Fermentation and Sanitary Significance.497504ENAraoItanoSatiyoArakawaNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama351927Über die in der Landwirtschaft Japans gebrauchten Samen. (Siebente Mitteilung.)457495ENMantarōKondōNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama341927Über die in der Landwirtschaft Japans gebrauchten Samen. (Sechste Mitteilung.)441455ENMantarōKondōNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama341927Spontane Entstehung einer missgestalteten Reispflanze ”Magatamaine“421424ENMantarōKondōSumitaFujimotoNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama341927Untersuchungen der verschiedenen Reiskörner geringerer Qualität. I. Die braun gefärbten enthülsten Reiskörner ”Tschamai“*.405419ENMantarōKondōTamotsuOkamuraNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama341927Studies on the Toxicity of Lime-Sulphur Mixture.†379404ENChukichiHarukawaNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama331927Temperature Relations to the Growth of Graminicolous Species of Helminthosporium: I. Effect of Temperature on the Vegetative and Reproductive Growth of Helminthosporium turcicum Passer. and Helminthosporium Maydis Nisikado et Miyake.†349377ENYosikazuNisikadoNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama331927Investigation on the Biilmann's Quinhydrone Electrode. III. (Further studies on the electrode and agar bridge.)337347ENA.ItanoS.ArakawaK.HosodaNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama331927Studies on the Carbon-Nitrogen Ratio and Microbiological Investigation of the Soil in Rice-field. I. The Carbon-Nitrogen Ratio.331336ENAraoItanoSatiyoArakawaNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama331927Kreuzungsuntersuchungen an Reispflanzen. II. Ueber die zweite (S-M-) Koppelungsgruppe mit besonderer Berücksichtigung ihrer korrelativen Beziehung zur Blütezeit.(Vorläuflge Mitteilung.)319330ENYasukeYamagutiNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama331927Untersuchungen über die Weiss-Gestreifte Reispflanze (Shimaine).291317ENMantarōKondōMotoharuTakedaSumitaFujimotoNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama331927Über die Ergebnisse der Pedigree-Zucht der Semisterilen Reispflanzen.275289ENMantarōKondōNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama321926Outline of The Ōhara Institute for Agricultural Research.267274ENNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama321926Studies on two Helminthosporium Diseases of Maize，Caused by Helminthosporium turcicum Passerini and Ophiobolus heterostrophus Drechsler (-Helm. Maydis Nisikado et Miyake).221266ENYosikazuNisikadoChuichiMiyakeNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama321926Studies on the cellulose.* (Publlation on cellulose No. I.)215219ENAraoItanoNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama321926Table for PH Values Corresponding to Electromotive Forces determined in Quinhydrone Electrode Measurements. II.*203214ENA.ItanoK.HosodaNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama321926Investigation on the Biilman's* Quinhydrone Electrode. I.193201ENA.ItanoK.HosodaNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama321926Soil Microorganismus and Activators.185191ENAraoItanoNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama321926Submergence as a Control Measure for the Rice-Borer, Chilo simplex Butler.177184ENChukichiHarukawaNo potential conflict of interest relevant to this article was reported.Verlag der Ōhara SchiōnōkaiActa Medica Okayama321926The Storage of Rice and Change of its Physical Properties during this Period.153175ENMantarōKondōNo potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013裏表紙・英文目次ENNo potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013奥付ENNo potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013平成24 年度 岡山大学教師教育開発センターの活動状況の概要ENNo potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013全学教職課程における「教職実践演習に向けての取組」―教科専門科目担当教員の意識に着目して―171178ENTsuyoshiKashidaHiroshiTakahataEijiEgiKayokoSodaTomotakaMishimaDaisukeGotoMasaruKaga10.18926/CTED/49519 岡山大学教師教育開発センター（以下，センター）は，全学教職コア・カリキュラム（以下，全学コア・カリ）の研究・開発と運営を行っている。教職実践演習については独自で開講する教育学部を除く7課程認定学部とセンターが協働して本格実施に向けた準備を行い，平成23年12月には「全学教職実践演習授業計画（案）」（以下，授業計画（案））を作成し，認識の共有化を図っている。一方で，各教職課程運営委員（以下，運営委員）からは学部内での説明や周知に関して不安や困難を述べる声も多く挙がった。そのため，平成24年2月にFD研修として教職実践演習のプレ試行を実施した。その結果，イメージがわくという成果と，教科専門科目担当教員（以下，教科教員）がどのように授業へコミットすればよいかという不安等の課題が顕在化した。そこで，教科教員が有している期待や不安等の意識を調査することにより，授業を構築するための成果と課題を明らかにした。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013教員志望学生の指導のあり方（５）―教職相談室の利用の実態から―162170ENKiyoshiOgawaYasumichiMatsubara10.18926/CTED/49517 教職相談室では主に教職志望の学生を対象に，小論文，集団討論，集団面接，個人面接，模擬授業など，教員採用試験に関する指導を中心とした様々な相談活動を行っている。今年度は，小論文指導において内容面を充実させるための指導の改善を行った。その結果，小論文を書いてくる学生が増加するとともに，小論文を書くことで培った力を面接にも生かすことができた。また，教員採用試験に最終合格した学生とそれ以外の学生では，教職相談室の利用回数に大きな差が見られた。教員採用試験に最終合格した学生の教職相談室の平均利用回数は15.94回であったのに対して，1次試験のみ合格の学生の平均利用回数は10.32 回であり，合格しなかった学生の平均利用回数は2.83回であった。更に，教職相談室に12月以降の早い時期に利用開始した学生ほど教員採用試験の合格率が高くなることが明らかになった。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013附属中学校における学校保健委員会の取組み―養護実習への活用を視野に入れて―152161ENYasukoOtaHirokoKamimuraHokumaMunakataKayokoMiyamotoShinichiroMonden10.18926/CTED/49516 岡山大学教育学部附属中学校における学校保健委員会の取組み，および学校保健委員会の資料の養護実習への活用について報告する。附属中学校の学校保健委員会は，@学校保健活動の全体像が理解されること，A課題が明確になる資料を工夫すること，B関係者の共通理解が図られること，の3つの視点から取組まれており，このことが日々の学校保健活動に対する有効な施策を協議するために重要であった。学校保健委員会の資料は同時に，養護実習において学生が学校保健活動を理解するための教材として活用できる。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013教職情報提供サービス「岡大教職ナビ」における成果と課題143151ENDaisukeSatohFumioYamaneShigenobuTakatsukaMasaruKaga10.18926/CTED/49515 岡山大学教師教育開発センターでは，教職情報提供サービス「岡大教職ナビ」の提供を平成23年11月より開始した。岡大教職ナビでは，NetCommons を活用して教職課程・教務関連情報やボランティア情報，各種イベント情報や教員・講師等募集情報，教員採用試験関連情報等をウェブサイトやメールを通して随時提供している。そこで開始より1 年間の経過を機に，利用者を対象としサービスの向上と改善を目的としたアンケート調査を実施した。その結果，多くの利用者が当サービスの必要性を感じながらも，有用性については実感できないことが判明した。その理由としては，個々のニーズに応じた情報提供がなされていない現状が浮き彫りとなった。そこで当センターとして利用方法の周知徹底と，情報の分類，配信方法の改善を検討し，更なるサービス向上に向けて対応する必要がある。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013特別支援学校での心理教育“ サクセスフル・セルフ”を用いた個別支援133142ENNaokaMizushimaMikayoAndo10.18926/CTED/49514 特別支援学校には，情緒が不安定になったり，対人関係において様々な適応困難を抱えたりする児童生徒も在籍している。そのため学習指導要領においても，「自立活動」という領域が設定されており，6つの区分「健康の保持」，「心理的な安定」，「人間関係の形成」，「環境の把握」，「身体の動き」，「コミュニケーション」の指導内容が示され重視されている。その実践としては種々の方法が用いられ，集団や個別での支援が行われている。心理教育“サクセスフル・セルフ”は，小中学校の児童生徒において心理行動上の問題を予防し，心の健康を育むことが報告されている。そこで本研究においては，特別支援学校の生徒に対し，心理教育“サクセスフル・セルフ”を用いた個別支援を行った。その結果，心理的安定と人間関係の形成に対する力をつけることに効果があることが示唆された。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013高度な専門性と実践的な指導力を有する教師の育成プログラム「教師力養成講座」の開発(4)―実践的な指導力を有する教師の育成―125132ENYasumichiMatsubaraKiyoshiOgawa10.18926/CTED/49513 平成21度より，年6回のペースで始めた本講座は，今年度で4年目となった。当初は，学生たちが，教員採用試験に合格したにもかかわらず，現場に出ることに不安感を持ち，相談に訪れることから，教師力をつけて，自信を持って卒業していけるようにしてやりたいと考え，この講座を立ち上げたものである。
現在は，その上に，現場からも，社会的にも，即戦力としての新採用教員が求められており，その意味で，実践力のある教員として卒業させることが大切だと考えた。その内容を報告する。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013中級後半および上級前半の学習者を対象とした地域文化・産業を学ぶ日本語教育の試み117124ENYukakoUchimaru10.18926/CTED/49512 本稿は中級後半および上級前半の日本語学習者を対象とした文化クラスでの実践報告である。日本刀，ジーンズ・学生服などの繊維産業，団扇と扇子，麺文化の比較と伝統製法のそうめん，Ｂ級グルメと地域の農産物・海産物，といった地域の文化・産業に根差したトピックをとりあげた。このクラスの特徴は，留学生だけでなく，副専攻日本語教育コースの学生と国際交流に興味を持つ日本人学生がボランティアとして授業に参加している点にある。協働学習およびプロジェクトワークが留学生にどのような刺激を与えたか，このような形式のクラスを運営する上での課題は何かをアンケート調査から明らかにする。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013仮説の提示と吟味の方法の工夫による小学校社会科授業改善107116ENNaokiSugitaToshinoriKuwabara10.18926/CTED/49511 本研究は，仮説の提示と吟味の方法の工夫により，授業の中で子どもたちが主体的に仮説の確からしさを高めていく授業構成を提案することを目的としている。現在，小学校段階においても森分孝治の提唱する探求学習が多く取り入れられ，科学的社会認識形成が目指されている。しかし，探求学習には，小学校で実施するには困難な部分がある。その第一は，仮説を提示させるための教師の具体的な手立てが示されていない点である。ただ子どもに発問をするだけでは，既有知識の少ない小学生では答えることが難しい。第二に，仮説の誤り排除が困難であるという点である。反証事例としての事実を認識し探し出すことは，小学生には難しい。以上の二点の課題を克服するため，C.S. パースのプラグマティズムにおける探究の理論をもとに，仮説の提示を促し，探求学習の検証過程に代わる新たな認識形成の方法を組み込んだ小学校社会科の授業構成を提案する。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013科学的に探究する能力の育成のために自然科学研究の手順の模擬体験を取り入れた高等学校理数科用授業プログラムの開発98106ENYoshihikoInada10.18926/CTED/49510 スーパーサイエンスハイスクール（SSH）指定校や理数科で実施する課題研究を充実させるために，自然科学研究の構成方法を実践的に学ぶことのできる授業を開発し試行実践した。自然科学分野での研究者養成で日常的に行われているOn the Job Training (OJT) を模した授業展開を構成し，実験・観察や研究をデザインするときに必要な要点を伝えることを目指した。素材として蒸発潜熱を測定する実験を用い，SSH 指定校である岡山県立倉敷天城高等学校の理数科１年生３９名を対象に７時間の授業実践を行った結果，科学的な仮説の設定方法や思考と発想のポイントを含めた研究の進め方の理解が進んだという結果が得られている。一方で，班内で積極的に議論しながら実験を進める姿勢には大きな向上は認められなかった。議論の場面を強制的に設定するだけでなく，議論を促す仕掛けが必要とされる。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013理想の教師像についての調査研究(2) : 学校長等のインタビューから9097ENFumioYamaneKatsuhikoKida10.18926/CTED/49509 岡山市内の幼稚園・小学校・中学校・高等学校及び特別支援学校の校長等に行った「理想の教師像」についてのインタビューにおける発言内容を分析し，新採用教員等若い教員に求める資質能力を明らかにした。また，学校長等の発言内容を中教審答申「教職生活の全体を通じた教員の資質能力の総合的な向上方策」において示された資質能力に基づいて分類し，校種間での比較・検討を行った。その結果，全校種の学校長等が重要であると考えている資質能力は，「総合的な人間力」のうちの「豊かな人間性や社会性」及び「コミュニケーション力」であった。幼稚園長・小学校長の発言には，「教職に対する責任感，探究力，教職生活全体を通じて自主的に学び続ける力」に分類された言葉が多かったのに対し，中学校長・高等学校長の発言には，「専門職としての高度な知識・技能」に分類された言葉が多かった。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013全学教職課程の質保証に関する実証的研究（１）―平成２２年度入学生の経年変化を中心に―8089ENHiroshiTakahataDaisukeGotoTomotakaMishimaTsuyosiKashidaEijiEgiKayokoSodaKayoTakahashiMasaruKaga10.18926/CTED/49493 教育学部を除く7つの課程認定学部（文，法，経，理，工，環境理工，農）とマッチング・プログラムコースに所属し，次年度（平成25年度）に「教職実践演習」の対象となる現3年生（平成22年度入学生）の，入学時から現在に至る教職志向並びに教育実践力に関する自己評価の経年変化を検証する。基礎データとして，教育学部・大学院教育学研究科との連携・協働によって教師教育開発センターが作成した教材「教職実践ポートフォリオ」を用いる。これは全学教職課程を履修する全ての学生が，自らの学習を記録し，その教育実践力の育ちを可視化するツールである。ここに現れたもののほか，センターが独自に開発し実施した意識調査の結果を用いつつ，総合大学における教員養成教育の質保証とカリキュラム・マネジメントのありかたを検討する。なお，本文中で「全学教職課程」と表記する場合は，上記の7学部とＭＰコースを対象とした教職課程のみを指すものとするNo potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013日本とドイツの前期中等教育段階における物理教育−現行教科書の比較考察−7079ENKenjiTanakaMasahiroMatsui10.18926/CTED/49490 ドイツ・ザクセン邦のギムナジウム中級段階の教科物理と日本の中学校の教科理科における物理分野に焦点を当て, 教科書などを手がかりにし, 比較を行い，期間・広がり・詳しさにおいて，違いを見いだした。ドイツでは第6学年から5年間にわたり通年で，日本では第7学年から3年間各学年限られた期間だけ学習されている。週授業時間数の合計はドイツの方が多い。ドイツでは，電磁気学・波動・力学・熱力学・天文学・原子物理学の分野があるが，日本では，電磁気学・力学・波動しかない。ドイツでは，内容に繰り返しと連続性があり，日本ではほとんどない。索引の密度を比較すると，ドイツは日本より大きい。実験に関しては，日本では代表的な実験を授業の中で実施するよう位置付けられているのに対し，ドイツでは多様な実験から自主的に選び実施することができるようになっていることで違っている。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013インクルーシブ教育に対する教員養成カリキュラム開発の動向と実際 : ハワイ大学マノア校における同時履修プログラムを中心に6169ENMunehisaYoshitoshiKirikoTakahashi10.18926/CTED/49489 インクルーシブ教育の取り組みが世界的な趨勢となっている。一方で，通常教育教員は，障害のある子どもを指導するための準備が必ずしも十分でないと感じており，インクルーシブ教育に関する知識やスキルの養成が大きな課題となっている。すなわち，インクルーシブ教育の展開に即した教員養成カリキュラムの開発が求められており，学習の内容や方法の検討が必要となっている。本稿では，インクルーシブ教育を先駆的に実践してきたアメリカ合衆国の取り組みに注目し，通常教育教員に対する特殊教育スキルの養成に関する全国的な動向を概観した。また，大学における具体的な教員養成カリキュラムの試みとして，州立ハワイ大学マノア校における同時履修プログラム（Dual preparation program）の基本的な内容について報告した。そして，わが国における新たな教員養成システムの展開に向けた検討材料を提起した。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013保育所保育における保育士の資質の問題点と課題5260ENAyakoNakahiraNorikoBabaToshiyukiTakahashi10.18926/CTED/49487 平成20年度厚生労働省告示の『保育所保育指針』第7章に，職員の資質向上が記載されている。保育士の資質向上の必要性は，今日，保育関係の研修会や学会等で多く述べられている。本論では，なぜ，資質向上が求められているのかを，保育士養成施設や保育現場に関する文献から，保育士が置かれている環境や現状や実態を明らかにすると共に，資質がどのような問題と関連しているのかに焦点を当て，保育士の資質向上に向けての打開策を考察するものである。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013「学生オペラ」を通した文化活動の推進（2）―教員と学生の内的評価の分析を中心に―4251ENMasakoMushiakiYokoOgawaRinkoHayakawa10.18926/CTED/49486 「学生オペラ」の発信は，教育現場で活躍できる人材育成と，岡山大学を文化活動の拠点とした文化・芸術活動の盛んな地域づくりを目指すことを目的として実施したものである。本稿では，（１）に引き続き，その取り組みの意義と課題について，教員（指導者）と学生の内的評価の分析を中心に考察を行った。学生対象のアンケート結果からは，全体の88％の学生が参加してよかったと感じており，また，教員養成におけるオペラ活動の意義を良い経験であると感じている学生は97％であった。大半の学生が，オペラのような総合的且つ横断的な分野の経験は，教育現場で活用でき，協調性や自主性を伸ばすことにもつながると考えており，活動の意義を共有していることがわかった。教員（指導者）のアンケート結果からは，それぞれの役割を発揮できたという連携の意義と，物理的体制の強化について課題が確認された。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013「学生オペラ」を通した文化活動の推進（1）―連携，革新，フィードバックの視点から―3241ENRinkoHayakawaYokoOgawaMasakoMushiaki10.18926/CTED/49485 「学生オペラ」の発信は，教育現場で活躍できる人材育成と，岡山大学を文化活動の拠点とした文化・芸術活動の盛んな地域づくりを目指すことを目的として実施したものである。本稿では，約半年間の準備期間の様子とその成果を報告し，筆者らが取り組んださまざまな連携のあり方と課題について考察した。連携に関しては，@教育学部内の教員の連携（教科内容専門の教員と教科教育専門の教員），A附属学校との連携，B他学部との連携，C地域や卒業生との連携に焦点を当てて検討した。また，オペラ終演後に実施したアンケート結果からは，来場された多くの方が非常に満足されており，これからも継続してほしいと要望していることが明らかになった。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013理科教育におけるWebベースの対話型3次元結晶構造教材2731ENJunjiYamakawa10.18926/CTED/49484 理科教育におけるWeb ベースの対話型3 次元結晶構造教材としてX3D 形式あるいは3D PDF を使ったシステムを比較検討した。どちらの形式もe- ラーニングシステムと高い親和性を持ち，また初学者と専門家の空間概念の把握に関するギャップを埋める教材として優れていると考えられた。データの継続使用を考えた場合，オープン規格であるX3D 形式と対応Web ブラウザを用いるシステムが適していた。一方，高品位な印刷が必要な場合は3D PDF とAdobe Reader を組み合わせたシステムが適していると考えられたが，将来に渡る継続利用を考慮した場合，このシステムはプロプライエタリである点に留意して運用しなくてはならないだろう。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013豪雨の出現頻度に注目した梅雨降水の気候学的特徴に関する探究的授業の開発（日降水量データを用いた附属中学校での実践）1726ENKuranoshinKatoNobuhikoHigashi10.18926/CTED/49483 梅雨は，アジアモンスーンの影響を顕著に受けた現象の一つである。本研究では，豪雨の起こり方に注目した日降水量データの分析活動や気象衛星画像の観察など通して梅雨について学ぶ学習プランを開発した。これは中学校理科での「日本の四季の天気」に関する探究的要素も含めた授業提案であるが，高等学校の『地学基礎』，『地学』，『地理』における活用も視野に置いた。研究科教員による附属学校園への相互乗り入れ授業の一環として，岡山大学附属中学校1年生を対象に授業実践を行い，結果について検討した。西日本では，東日本と違い，『大雨日』が頻繁に出現することを反映して，気候学的に総降水量が大変多くなる。授業では，そのような特徴の一端を九州の長崎と関東の東京の6〜7月における1971〜1998 年の日降水量の表から読み解く作業・考察を，中心的活動の一つに据えた。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013音楽が情動におよぼす影響と音楽的行動の発達 : 広汎性発達障害児に対する音楽を用いた支援のための知見1016ENRieYokouchiSatoshiSanada10.18926/CTED/49482 本研究では，音楽を用いた支援を行う際の基礎的条件になると考えられる音楽の三要素が，情動におよぼす影響について検討し，さらに，乳幼児期の音楽的行動の発達についても既報論文に基づいて展望的研究を行った。リズムは人と人との情動的結びつきを強化させ，メロディーは安心や懐かしさを感じさせ，ハーモニーは心理的あるいは身体的な緊張と弛緩を生み出すことが示唆された。音楽的行動の発達では，スプーンでものを口に運ぶ18か月ごろからタンバリンを振り鳴らす行動が見られ，ひもを結ぶなど手指の分化が著しくなる5 歳ごろから旋律楽器での分担奏が可能となることなどが示唆された。効果的な支援を行うためには，音楽の三要素の特性を理解し情動的影響を企図した支援を行なうこと，音楽的行動の発達過程を参考に対象児の音楽的技術の獲得水準を判断した楽器や曲の選択が重要であることを提言した。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013今，岡山の学校教育は 中学校現場で起きていること，そして改善に向けて19ENHideakiIwadou10.18926/CTED/49481 文部科学省の調査（児童生徒の問題行動等生徒指導上の諸課題に関する調査H24）によると，岡山県内の小・中学校の暴力行為，不登校の出現率が全国比較では大変高く，学力・学習状況調査でも国語，数学ともに通過率が低いことが報告され，憂慮される事態にある。その原因は複雑多岐に渡っており，教育委員会や学校現場は解決に向け総力をあげて取り組んでいるが、大変困難な状況が見られる。県下の教育関係者すべては当事者意識と責任をもってかけがえのない一人ひとりの子どもたちに焦点を当てた本来の教育を再生することが急務である。
私は，平成23年3月に中学校長を最後に定年退職し，現在は教育現場を離れているが，現役時代（幼・小・中学校・特別支援学校）を自己反省する意味も含め，中学校を中心としてその現状と改善に向けた方策についてまとめてみた。No potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013表紙・目次ENNo potential conflict of interest relevant to this article was reported.岡山大学教師教育開発センターActa Medica Okayama2186-132332013岡山大学教師教育開発センター紀要 第3号 全文 （一括ダウンロード用）ENNo potential conflict of interest relevant to this article was reported.大原奨農會Acta Medica Okayama31922害虫驅除劑につきて150178ENNo potential conflict of interest relevant to this article was reported.大原奨農會Acta Medica Okayama31922植物の病害抵抗性に就きて125149ENNo potential conflict of interest relevant to this article was reported.大原奨農會Acta Medica Okayama31922膠質化學大意99124ENNo potential conflict of interest relevant to this article was reported.大原奨農會Acta Medica Okayama31922農業界の社會問題3998ENNo potential conflict of interest relevant to this article was reported.大原奨農會Acta Medica Okayama31922我園藝の將來138ENNo potential conflict of interest relevant to this article was reported.Optical Society of AmericaActa Medica Okayama2156-7085322012Scanning and non-scanning surface plasmon microscopy to observe cell adhesion sites354359ENKoyoWatanabeKojiMatsuuraFukukazuKawataKotaroNagataJunNingHiroshiKanoWe observe adhesion sites of a cell on a substrate with high resolution. Since this observation requires interfacial measurements between the cell and the substrate, we employ scanning localized surface plasmon microscopy. We experimentally show that focal adhesion sites of a mouse muscle cell can be observed without fluorescent labeling. We also show that a non-scanning surface plasmon microscope combined with the scanning localized surface plasmon microscope contributes to observing an entire cell adhesion site and identify regions of interest.No potential conflict of interest relevant to this article was reported.岡山大学埋蔵文化財調査研究センターActa Medica Okayama31990岡山大学埋蔵文化財調査研究センター報 第3号ENNo potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-306933-41972明治期岡山県地方工業の動向について―その位置づけと検討の方向―179198ENH.Kandachi10.18926/OER/42390No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-306933-41972C.Th. Hermann の統計思想―その「統計批判」論を中心として―155178ENM.Urata10.18926/OER/42389No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-306933-41972無産政党と都市政策―大正デモクラシー期地方財政の一断章―128154ENC.Sakamoto10.18926/OER/42388No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-306933-41972商法の計算規定について100127ENS.Takeshita10.18926/OER/42387No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-306933-41972ドル問題とアメリカの国際収支7799ENK.Tatebe10.18926/OER/42386No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-306933-41972量的経済政策論の諸類型4676ENT.Fujimoto10.18926/OER/42385No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-306933-41972トレード・オフ関係についての一考察―所得政策の批判のために―2445ENI.Nagatomo10.18926/OER/42384No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-306933-41972井上準之助小論―大正8年5月，銀行引受手形日銀再割引制度の開始を中心として―123ENI.Tanaka10.18926/OER/42383No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-3069321971再生産表式の形成過程（III）83124ENA.Takagi10.18926/OER/42382No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-3069321971Thompsonの組織行動論の考察（II）5782ENY.Kajimoto10.18926/OER/42381No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-3069321971公共財と不確実性についての一試論4756ENS.Takemura10.18926/OER/42380No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-3069321971ザクセンにおける牧羊業の興隆と衰退146ENN.Matsuo10.18926/OER/42379No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-30693119713月革命期およびフランス革命期のザクセンにおける農民運動121150ENN.Matsuo10.18926/OER/42378No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-3069311971チェンバリンを中心とした独占理論（II）88120ENY.Hashimoto10.18926/OER/42377No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-3069311971「財政学方法論」への一視点（上）―経済学と国家によせて―6287ENC.Sakamoto10.18926/OER/42376No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-3069311971“社会学主義”と統計2861ENK.Sgimori10.18926/OER/42375No potential conflict of interest relevant to this article was reported.岡山大学経済学会Acta Medica Okayama0386-3069311971A. L. von Schlozer の統計思想127ENM.Urata10.18926/OER/42374No potential conflict of interest relevant to this article was reported.岡山大學放射能泉研究所Acta Medica Okayama31950裏表紙・英文目次ENNo potential conflict of interest relevant to this article was reported.岡山大學放射能泉研究所Acta Medica Okayama31950奥付ENNo potential conflict of interest relevant to this article was reported.岡山大學放射能泉研究所Acta Medica Okayama31950新しい試藥によるカルシウムの直接比色定量法及び直接滴定法3942ENTakashiAshizawa10.18926/40364The anthor found that azocal-A reacts only with calcium, and devised a direct colorimetric, and a direct titration method for calcium determination using azocal-A as an indicator, and obtained a satisfactory result. Accuracy : detectable amount in NaOH……0.28 γ, of Ca ; detectable amount in NH(4)OH……2 γ, of Ca. Sensibility……1 : 125,000 & 1 : 17,500 respectively. Interfering substances : Fe, U, Ni, Co, Hg, Ag, citrate, tartarate, oxalate, large amount of NH(4) salts, Sr, Mg. Not interfering subst. : Ba, F, acetate and silicate. Reagents : Saturated soln. of azocal-A in weak NaOH soln.. Spot test procedure : Place a drop of the acid or neutral test soln. upon white spot plate, add 1 drop of azocal-A soln., and mix them. If a yellow color appears, calcium is present. Colorimetric method: Transfer water sample containg not more than 0.05 mg of calcium, and not more than 5 mg of Fe, Mn, Mg, etc. to a 20 cc colorimetric tube, add 0.5-1 cc of azocal-A soln. and 0.5 cc of 6N-NaOH soln.. Allow it to stand for 10 minutes. Then compare the resulted yellow color with standard Ca soln. prepared similarly and simultaneously. Volumetric method : Amount determinable : 0.1 g of calcium. Transfer 40 cc of sample containg 5-100 mg to a 100 cc Erlenmeyer's flask, add 0.5 cc of 6N-HCl, add azocal-A to the amount of pink color as caused by methyl orange in acid soln.. Make alkaline with 1 cc of 6N-NaOH. Add 10 cc alcohol to every 40 cc of the sample solution. Then its color turns to yellow. Titrate with 0.1 N oxalate soln.. 1.0 cc of 0.1 N oxalate soln. is equivalent to 2.0 mg of Ca. Absorption band of the acid soln. at 4900 A, alkaline soln. at 5000 A, Ca-compound at 4300 A. The azocal-A is o-carboxy-benzol-azo-2-naphtol 3, 6-disulfonic acid prepared from anthranilic acid and R-salt.No potential conflict of interest relevant to this article was reported.岡山大學放射能泉研究所Acta Medica Okayama31950坂H泉に關する研究（第5報） 坂H泉に含まれる鐵の多核錯鹽3538ENTakashiAshizawa10.18926/40363No potential conflict of interest relevant to this article was reported.岡山大學放射能泉研究所Acta Medica Okayama31950三朝溫泉の化學的研究（1-8）2134ENTakashiAshizawa10.18926/40362No potential conflict of interest relevant to this article was reported.