result 47892 件
| Author | Murata, Atsuo| Moriwaka, Makoto| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Ghazalli Zakri| Murata, Atsuo| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Wang Shuguang| Murata, Atsuo| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Hasuike Takashi| Ishii Hiroaki| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Hanaa, E.Sayed| Hossam, A.Gabbar| Soheir, A. Fouadc| Khalil, M. Ahmedc| Miyazaki, Shigeji| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Hanaa, E.Sayed| Hossam, A.Gabbar| Miyazaki, Shigeji| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Handa, Hisashi| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Matsui Takeshi| Sakawa Masatoshi| Kato Kosuke| Matsumoto Koichi| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Hara Akira| Yamaguchi Tomohisa| Ichimura Takumi| Takahama Tetsuyuki| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| Author | Mera Kazuya| Ichimura Takumi| |
|---|---|
| Published Date | 2008-12 |
| Publication Title | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| Volume | volume2008 |
| Issue | issue1 |
| Content Type | Conference Paper |
| JaLCDOI | 10.18926/14789 |
|---|---|
| Title Alternative | IgE系アレルギー反応はアトピー型気管支喘息の白血球ロイコトリエンB4（LTB4）およびC4（LTC4）産生を促進させ，喫煙は気道過敏性を亢進させる |
| FullText URL | 74_042_047.pdf |
| Author | Ashida, Kozo| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Iwagaki, Naofumi| Nagata, Takuya| Fujii, Makoto| Takata, Shingo| Yokoi, Tadashi| Hamada, Masanori| Tanizaki, Yoshiro| |
| Abstract | Influences of IgE-mediated allergy and cigarette smoking on pathophysiology, evaluated by bronchial hyperresponsiveness and the generation of LTB4 and LTC4, of asthma were examined in 69 patients with asthma sensitive to inhalant allergens such as house dust mite and Candida albicans.
1 . Bronchial byperresponsiveness was significantly higher in previous and current smokers of asthmatics than in never-smokers. 2 . The generation of leukotrienes 84 (LTB4) and C4 (LTC4) by leucocytes was significantly larger in patients with serum IgE over 350 IU/ml than in those with serum IgE less than 150 IU/ml (LTB4 : p |
| Keywords | lgE-mediated allergy bronchial hyperresponsiveness LTB4 LTC4 asthma cigarette smoking |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2004-02-01 |
| Volume | volume74 |
| Start Page | 42 |
| End Page | 47 |
| ISSN | 1348-1258 |
| language | English |
| File Version | publisher |
| NAID | 120002308637 |
| JaLCDOI | 10.18926/14788 |
|---|---|
| Title Alternative | 肺気腫と喘息のHRCT上のlow attenuation are（LAA）の性質の差。喫煙との関連を含めて |
| FullText URL | 74_035_041.pdf |
| Author | Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Iwagaki, Naofumi| Nagata, Takuya| Fujii, Makoto| Takata, Shingo| Yokoi, Tadashi| Hamada, Masanori| Tanizaki, Yoshiro| |
| Abstract | The low attenuation area (LAA) of the lungs on high resolution computed tomography (HRCT) was evaluated in 20 asthmatics (10 ex-smokers and 10 never-smokers) and 10 patients with pulmonary emphysema (all ex-smokers) by ventilatory function, lung volume, DLco, and a ratio of expiratory LAA/inspiratory LAA. 1 . The % LAA of the lungs on HRCT was significantly larger in patients with pulmonary emphysema(PE) than in those with asthma, but there was not significant difference in % LAA between ex-smokers and never-smokers of asthmatics. 2. A ratio of expiratory Winspiratory LAA was significantly higher in patients with PE than in those with asthma , and the ratio was significantly higher in ex-smokers of asthmatics than in never-smokers (p<0.05). 3 . The difference in % residual volume and % DLco was significant between asthma and PE , and between ex - smokers and never-smokers of asthmatics (% RV : p<0.05, DLco : p<0.05) . 4 . The difference in the values of % FVC, % FEV(1) .O, and FEV1.0% was significant between asthma and PE, but not significant between ex-smokers and never- smokers of asthmatics. The results suggest that the difference in a ratio of expiratory W inspiratory LAA, % RV and % DLco was significant between ex - smokers and never - smokers of asthmatics , and cigarette smoking induces more irreversible changes of the lungs. |
| Keywords | low attenuation area asthma pulmonary emphysema cigarette smoking |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2004-02-01 |
| Volume | volume74 |
| Start Page | 35 |
| End Page | 41 |
| ISSN | 1348-1258 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308507 |
| JaLCDOI | 10.18926/14787 |
|---|---|
| FullText URL | 74_026_034.pdf |
| Author | Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Iwagaki, Naofumi| Nagata, Takuya| Fujii, Makoto| Takata, Shingo| Yokoi, Tadashi| Hamada, Masanori| Tanizaki, Yoshiro| |
| Abstract | To determine the characteristics of the elderly in high - resolution computed tomography (HRCT) lung densitometry, mean lung density (MLD) and relative area of the lungs showing attenuation values less than -950 HU (RA(950)) on HRCT were evaluated in nonsmoking control subjects (n = 80) and patients with asthma (n = 80) in relation to their age and pulmonary function. MLD was significantly decreased, and RAW was significantly increased with increasing age in both asthmatics and controls. The MLD values were significantly lower in asthmatics compared with controls in subjects aged between 60 and 69 years and over age 70. RAgsov alues were significantly higher in asthmatics compared with controls in subjects aged between 50 and 59 years, between 60 and 69, and over 70. % FEV(1) and FEV(1) / FVC were significantly decreased in elderly asthmatic patients over 70 years of age compared with the values in those under 49. Percent residual volume (% RV) was significantly larger in patients over 70 years of age than in those between 50 and 59, and under 49 years. RAW was significantly larger in patients with steroid-dependent intractable asthma (SDIA) between 50 and 59 years of age, and between 60 and 69 compared with RA 950 in those without SDIA. However, RAW did not differ significantly between SDIA and non-SDIA in patients over age 70. The results suggested that in % LAA of the lungs on HRCT was significantly increased in the elderly subjects with and without asthma, and it was significantly higher in the elderly asthmatics than the elderly controls. |
| Keywords | aging (加齢) high-resolution computed tomography (高分解能CT) low attenuation area (低吸収域) mean lung density (平均CT値) pulmonary function (肺機能) |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2004-02-01 |
| Volume | volume74 |
| Start Page | 26 |
| End Page | 34 |
| ISSN | 1348-1258 |
| language | English |
| File Version | publisher |
| NAID | 120002308286 |
| JaLCDOI | 10.18926/14784 |
|---|---|
| Title Alternative | 長期間の喫煙は高齢者気管支喘息における気道過敏性と関連した白血球LTB4産生を亢進させる |
| FullText URL | 74_018_025.pdf |
| Author | Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Iwagaki, Naofumi| Nagata, Takuya| Fujii, Makoto| Takata, Shingo| Yokoi, Tadashi| Hamada, Masanori| Tanizaki, Yoshiro| |
| Abstract | Abstract : Influence of cigarette smoking on leukotriene 84 (LTB4) generation by leucocytes associated with bronchial hyperresponsiveness was examined in 110 patients with asthma. l. The frequency of positive RAST score for inhalant allergens and LTB4 generation by leucocytes were significantly larger in previous and current smokers than in nonsmokers. 2. In nonsmokers, bronchial hyperresponsiveness was significantly higher in asthmatics under the age of 49 years compared with that in patients between 50 and 59 years, between 60 and 69 years, and those over age 70 years. In contrast, no significant differences were present between bronchial hyperresponsiveness and patient age in previous and current smokers. 3. In patients over age 60, bronchial hyperresponsiveness was significantly higher in previous and current smokers than in nonsmokers. In these patients, LTB4 generation was significantly more increased in previous and current smokers than in nonsmokers. 4. A significant correlation was observed in asthmatics of nonsmokers between LTB4 generation and bronchial hyperresponsiveness . 5. LTC4 generation was significantly higher in previous and current smokers than in nonsmokers in patients under age 49 years. These results show that in patients over age 60 years, cigarette smoking induces an increase in the generation of LTB4, leading to an increase in bronchial hyperresponsiveness . |
| Keywords | cigarette smoking asthma LTB4 generation LTC4 generation bronchial hyperresponsiveness |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2004-02-01 |
| Volume | volume74 |
| Start Page | 18 |
| End Page | 25 |
| ISSN | 1348-1258 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308359 |
| JaLCDOI | 10.18926/14783 |
|---|---|
| FullText URL | 74_011_017.pdf |
| Author | Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Iwagaki, Naofumi| Nagata, Takuya| Fujii, Makoto| Takata, Shingo| Yokoi, Tadashi| Hamada, Masanori| Tanizaki, Yoshiro| |
| Abstract | Clinical effects of long-term spa therapy for 4 years were estimated in 8 patients of pulmonary emphysema (4 with spa therapy and 4 without spa therapy) by pulmonary function and morphological changes of peripheral airspaces of the lung on
high - resolution computed tomography (HRCT).
1 . The values of % FVC, % FEV1.0, and FEV 1.0% did not significantly change for 4year observation both in patients with spa therapy and those without spa therapy.
2. The OLco value significantly decreased from 69.9% at the initial level to 48.8% after 4-year observation in patients without spa therapy (p |
| Keywords | spa therapy (温泉療法) pulmonary emphysema (,肺気腫) % RV % DLco % low attenuation area of the lung |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2004-02-01 |
| Volume | volume74 |
| Start Page | 11 |
| End Page | 17 |
| ISSN | 1348-1258 |
| language | English |
| File Version | publisher |
| NAID | 120002308395 |
| JaLCDOI | 10.18926/14782 |
|---|---|
| Title Alternative | Spa therapy for patients with respiratory disease. Analysis of 2295 patients admitted at Misasa Medical Center for last 22 years from 1982 to 2003 |
| FullText URL | 74_001_010.pdf |
| Author | Tanizaki, Yoshiro| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Iwagaki, Naofumi| Nagata, Takuya| Fujii, Makoto| Takata, Shingo| Yokoi, Tadashi| Hamada, Masanori| |
| Abstract | 1982年から2003年までの22年間に当医療センターで入院加療した2295例を対象に5年間毎にその年次推移を検討した｡2295例のうちわけは,気管支喘息1400例(61.0%),COPD510例(22.2%),その他385例であった｡1.気管支喘息は,第1期(1982-1986年)の5年間では,平均11.4例/年であったが第4期(1997-2001年)では平均93例と初期と比べ8.2倍の増加が見られた｡また,第5期(最近の2年間)では87.0例/年であった｡そのなかのSDIA(steroid-dependentintractableasthma)の頻度は初期の68.4%から第4期では29.0%,第5期23.6%にまで低下する傾向を示した｡ 2.COPD症例は,初期の5年間(1982-1986年)では平均5.2例/年から第4期には44.6例/年へと8.7倍の,また第5期では47.5例/年へと9.1倍の増加が見られた｡また,そのなかの肺気腫が占める割合は初期の19.2%から第4期では76.7%,第5期では87.4%と明らかな増加傾向を示した. 3.気管支喘息およびCOPD症例の年齢別検討では,60歳以上の症例の頻度は第1期では30.1%であったが,第4期では68.0%,そして第5期では87.4%と,年々その頻度は高くなっていく傾向が見られた｡すなわち,最近22年間の年次推移からは,温泉療法を必要とする呼吸器疾患患者が増加しつつあること,そしてその年令は年々高くなる傾向にあることが示されている｡ |
| Keywords | 喘息 COPD 温泉療法 高齢者 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2004-02-01 |
| Volume | volume74 |
| Start Page | 1 |
| End Page | 10 |
| ISSN | 1348-1258 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308446 |
| Author | 三朝医療センター| |
|---|---|
| Published Date | 2003-02-01 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Volume | volume73 |
| Content Type | Others |
| Author | Matsubara, Fumie| 光延 彰子| Nagata, Takuya| Tanizaki, Yoshiro| |
|---|---|
| Published Date | 2003-02-01 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Volume | volume73 |
| Content Type | Data or Dataset |
| JaLCDOI | 10.18926/14779 |
|---|---|
| FullText URL | 73_111_114.pdf |
| Author | 寺崎 佳代| 山本 貞枝| 吉尾 慶子| 西村 伸子| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| |
| Abstract | 呼吸器疾患症例における温泉療法の効果(自覚症状,事物投与量など)早,有効と思われた温泉療法の種類,終了後の経過(1年後)などについて,気管支喘息102例を対象にアンケート調査を行った｡ その結果,温泉療法開始1週間で自覚症状が改善された症例が71.5%,副腎皮質ホルモンの減量が可能であった症例が65.6%,通院後1年間は,入院時に比べ症状が改善されている症例が61.8%,さらに,退院時より改善されている症例が53.9%であった｡ これらのことから,当院の温泉療法により症状が改善したことと,体調コントロールを身につけることにより,退院後1年以上経過しても,体調が良好に維持されていることが示唆された｡ |
| Keywords | 温泉療法 アンケート 呼吸器疾患 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2003-02-01 |
| Volume | volume73 |
| Start Page | 111 |
| End Page | 114 |
| ISSN | 1348-1258 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308409 |
| Author | 西村 伸子| |
|---|---|
| Published Date | 2003-02-01 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Volume | volume73 |
| Content Type | Others |
