result 47501 件
| JaLCDOI | 10.18926/15093 |
|---|---|
| Title Alternative | 気管支喘息に対する複合温泉療法の作用機序 1.温泉療法の評価方法との関連 |
| FullText URL | 067_085_091.pdf |
| Author | Mitsunobu, Fumihiro| Mifune, Takashi| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | Action mechanisms of complex spa therapy (swimming training in a hot spring pool, inhalation with iodine salt solution, and fango therapy) were studied in relation to patient age, clinical asthma type, and airway inflammation. Actions of spa therapy were observed by two clinical effects : direct and indirect effects. Improvement of subjective symptoms, ventilatory function, and bronchial hyperresponsiveness was observed as direct effects of spa therapy, and improvement of suppressed function of adrenocortical glands as indirect effects of the therapy. The clinical effects of spa therapy were higher in patients over the age of 40. Regarding clinical asthma type, the effects were larger in patients with type Ib and type II asthma than in those with type Ia. The efficacy of spa therapy was closely related with airway inflammation in patients with type Ib and type II asthma. |
| Keywords | complex spa therapy (複合温泉療法) clinical asthma type (臨床病型) ventilatory function (換気機能) bronchial hyperresponsiveness (気道過敏性) adrenocortical glands (副腎皮質) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 85 |
| End Page | 91 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307192 |
| JaLCDOI | 10.18926/15092 |
|---|---|
| Title Alternative | Spa therapy and drug therapy in patients with bronchial asthma |
| FullText URL | 067_107_114.pdf |
| Author | Tanizaki, Yoshiro| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kouzou| Yokota, Satoshi| Takeuchi, Kazuaki| Nawa, Yuichiro| |
| Abstract | 気管支喘息は,その臨床病態より,Ia.単純性気管支攣縮型,Ib.気管支痙攣縮+過分泌型,Ⅱ.細気管支閉塞型の3つの基本病型に分けることができる｡また,発症病態からは,アトピー型と非アトピー型に分けられる｡気管支喘息に対する温泉療法や薬物療法の際には,これらの臨床病態や発症病態を十分把握した上で最も適切な治療法を選ぶ必要がある｡気管支喘息に対する薬物療法では,気管支拡張薬,去痰薬,抗アレルギー薬,副腎皮質ホルモンなどがその主たるものであるが,特に薬物療法では気管支拡張作用と抗炎症作用が重要である｡一方,温泉療法では,気道の浄化作用や気管支粘膜の正常化作用などが得られ,臨床病型では,過分泌型や細気管支閉塞型に対してより効果的である｡また,発症病態からすれば,アトピー型ではヒスタミンとロイコトリエンが,非アトピー型ではロイコトリエンがより優勢な化学伝達物質であり,このような発症病態を十分把握した上で,適切な抗アレルギー薬を選ぶ必要が ある｡ |
| Keywords | 気管支喘息 (bronchial asthma) 臨床病型 (clinicaI classification) アトピー型 (atopic asthma) 温泉療法 (spa therapy) 薬物療法 (drug therapy) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 107 |
| End Page | 114 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307684 |
| JaLCDOI | 10.18926/15091 |
|---|---|
| Title Alternative | Ⅱ型喘息(細気管支閉塞型)と気管支肺胞洗浄液の好中球数 |
| FullText URL | 067_079_084.pdf |
| Author | Tanizaki, Yoshiro| Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Ochi, Koji| Harada, Hideo| Ikeda, Satoru| Taketa, Kazuhisa| |
| Abstract | Bronchial asthma is classified into three types ; type Ia (Ia-1 and Ia-2), type Ib, and type Ⅱ, by clinical symptoms (clinical diagnosis). Asthma is also classified by clinical findings and examinations (score diagnosis). Both classification systems show that markedly increased proportion of BAL neutrophils and marked decrease in % V25 value are characteristic of type Ⅱ, bronchiolar obstruction, asthma. However, there are some type Ⅱ asthma patients without BAL neutrophilia. In these patients, age is higher compared to those with BAL enutrophlia. Decrease in FEV1.0% value and decrease in the proportion of BAL lympocytes and serum IgG level, are not so remarkable as decrease in those with BAL neutrophilia. It has been suggested that type Ⅱ asthma with BAL neutrophilia correlates with suppression of humoral and cellular immunity, and same type of astma without BAL neutrophilia is in part caused by aging. |
| Keywords | Asthma classification (喘息分類) BAL lymphocytes (BALリンパ球) BAL neutrophils (BAL好中球) % V25 value Ⅱ型喘息 |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 79 |
| End Page | 84 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307924 |
| JaLCDOI | 10.18926/15090 |
|---|---|
| Title Alternative | Gastro-biliary motility in patients with non-ulcer dyspepsia |
| FullText URL | 067_075_078.pdf |
| Author | Mizushima, Takaaki| Yamamoto, Ryoichi| Matsumura, Naoki| Chowdhury, Riaz| Kato, Tadahiro| Ochi, Koji| Tanaka, Juntaro| Harada, Hideo| Yokota, Satoshi| Mitsunobu, Fumihiro| Mifune, Takashi| Tanizaki, Yoshiro| |
| Abstract | 現在,上腹部不定愁訴の原因は特定されていない｡その原因を解明するため,上腹部不定愁訴患者8人と健常対照者10人に対して液体食の胃排出能と,食事負荷による胆嚢収縮能を測定した｡胃排出時間,胆嚢収縮能はいずれも両者に有意な差は認められなかった｡健常対照者では胃排出時間と胆嚢収縮時間に有意な相関関係が認められたが,上腹部不定愁訴群では相関関係は認められなかった｡上腹部不定愁訴の原因として胃･胆嚢協調運動障害の存在が示唆 された。 |
| Keywords | 胃運動 (Gastric motility) 胆嚢運動 (Biliary motility) 不定愁訴 (indefinite complaint) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 75 |
| End Page | 78 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308012 |
| JaLCDOI | 10.18926/15089 |
|---|---|
| Title Alternative | Usefulness of retinol binding protein as a marker for the assessment of nutritional uptake for the preparation of colonosocpy |
| FullText URL | 067_071_074.pdf |
| Author | Kato, Tadahiro| Hasuoka, Hideaki| Ochi, Koji| Mizushima, Takaaki| Chowdhury Riaz| Matsumura, Naoki| Yamamoto, Ryoichi| Tanaka, Juntaro| Harada, Hideo| Akiyama, Tsuneo| Yokota, Satoshi| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| |
| Abstract | 大腸内視鏡検査の前処置を栄養面から評価する目的で前処置前後にrapid turnover proteinである血中レチノール結合蛋白の変動を検討した｡前日に普通食を用い,当日ニフレックを使用した10例,検査1日前に低残渣食を用いた27例,通常の前処置では良好な腸管洗浄が得られないために検査前2日間低残渣食を用いた27例の3群について,前処置開始前と検査終了後に血中レチノール結合蛋白の変動をみたところ,検査前2日間低残渣食服用群で有意の低下を認めた｡前日普通食群では検査前後で変化を認めず,1日低残渣食服用群では低下傾向を認めたが,有意差は認めなかった｡これまで前処置の成否は腸管洗浄度の面で評価されてきたが,血中レチノール結合蛋白を目標として用いることにより栄養面から評価することができることが考えられた。 |
| Keywords | レチノール結合蛋白 (retinol binding protein) 大腸内視鏡 (colonoscopy) 前処置 (preparation) 栄養評価 (nutritional assessment) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 71 |
| End Page | 74 |
| ISSN | 0918-7839 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307681 |
| JaLCDOI | 10.18926/15088 |
|---|---|
| Title Alternative | サーモグラフィーによる体表面温度の測定 |
| FullText URL | 067_063_070.pdf |
| Author | Hosaki, Yasuhiro| Nawa, Yuichiro| Takeuchi, Kazuaki| Tsugeno, Hirofumi| Ashida, Kozo| Yokota, Satoshi| Mitsunobu, Fumihiro| Mifune, Takashi| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| Ikeda, Satoru| Taketa, Kazuhisa| |
| Abstract | Body Surface Temperature was observed by thermography. The surface temperature of a healthy person's lower limbs, after being cooled in a water bath, increased in parallel with time. Patients with Diabetes Mellitus had different patterns in the rate of increase of the surface temperature. After cold loading, one patient had a 99% recovery ratio of surface temperature, the same level as healthy volunteers (83%, and 88%), as calculated by a picture processing program with the computerized thermotracer. However, the recovery ratio of other patients was poorer, ranging from 56% to under 6% recovery. This measurement of elevation of body temperature is useful for the estimation of peripheral blood flow in patients with lower limbcirculation failure. |
| Keywords | Thermography (サーモグラフィー) Diabetes Mellitus (糖尿病) Peripheral Circulation (末梢循環) Cold Loading (冷水負荷) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 63 |
| End Page | 70 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307566 |
| JaLCDOI | 10.18926/15087 |
|---|---|
| Title Alternative | 気管支喘息症例に対する鼻腔内ステロイド療法 |
| FullText URL | 067_057_062.pdf |
| Author | Mifune, Takashi| Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Takeuchi, Kazuaki| Nawa, Yuichiro| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | Bronchial asthma is often accompanied with allergic rhinitis or chronic sinusitis. Mucosal abnormalities of sinonasal cavity may influence lower respiratory responses in patients with asthma. We experienced a case of 72-year-old woman with asthma, who had dyspnea on exertion and a large volume of expectoration of more than 100mℓ a day. Furthermore she had nasal symptoms (nasal obstruction and rhinorrea) with prominent post-nasal discharge. Computed tomography (CT) scans of sinonasal cavity revealed marked thickness of nasal mucosa. Although her asthma symptoms such as wheezing and dyspnea improved by administration of bronchodialators, antiallergic agent, and beclomethason di isocyanate (BDI) accompanied with spa therapy after admission, the volume of expectoration revealed no decrease and her peak expiratory flow (PEF) didn't increase. The volume of expectoration and the PEF showed marked improvement after starting of intranasal glucocorticoid therapy. It is suggested from her clinical course that treatment with intranasal glucocorticoids is very important in asthmatic patients with mucosal abnormalities of sinonasal cavity. |
| Keywords | bronchial asthma (気管支喘息) rhinitis (鼻炎) intranasal steroid therapy (鼻腔内吸入ステロイド療法) expectoration (喀痰排出) peak expiratory flow (ピークフロー) |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1996-11 |
| Volume | volume67 |
| Start Page | 57 |
| End Page | 62 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002307814 |
| Author | 教育実践総合センター| |
|---|---|
| Published Date | 2007-03-10 |
| Publication Title | 岡山大学教育実践総合センター紀要 |
| Volume | volume7 |
| Issue | issue1 |
| Content Type | Others |
| Author | 教育実践総合センター| |
|---|---|
| Published Date | 2006-03-25 |
| Publication Title | 岡山大学教育実践総合センター紀要 |
| Volume | volume6 |
| Issue | issue1 |
| Content Type | Others |
| JaLCDOI | 10.18926/15065 |
|---|---|
| Title Alternative | The biochemical and biological activities of JUN. |
| FullText URL | 062_071_075.pdf |
| Author | Mitsunobu, Fumihiro| Kitani, Hikaru| Okazaki, Morihiro| Mifune, Takashi| Asaumi, Noboru| Tanizaki, Yoshiro| |
| Abstract | c-junはニワトリの癌ウイルスから分離された癌遺伝子（v-jun）のproto－oncogeneであり，その遺伝子産物は細胞内転写促進因子AP－1の主成分である。v－jun，c-junのトランスフォーム能を検討するために，我々はv-jun，ニワトリc-jun遺伝子さらにJUN遺伝子の種々の組換え体を複製能を持つレトロウイルスベクター（RCAS）に挿入し，CEF細胞（ニワトリ胎児線維芽細胞）にトランスフェクションした。その結果4か所存在する両者の構造的相違のうち，アミノ末端近くの27アミノ酸の欠損と3' untranslated regionの欠損が十分なトランスフォーム能と転写促進能発現に必須であることが明らかとなった。これらの部分がどのように機能発現に関与しているかは，これからの研究を待たねばならない。 |
| Keywords | 癌遺伝子 (Oncogene) JUN遺伝子 (JUN gene) レトロウイルスベクター (Retrovirus Vector) トランスフェクション (Transfection) トランスフォーム (Transform) |
| Publication Title | 環境病態研報告 |
| Published Date | 1991-08 |
| Volume | volume62 |
| Start Page | 71 |
| End Page | 75 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002307874 |
| Author | 岡山大学環境理工学部広報委員会| |
|---|---|
| Published Date | 2009-03-16 |
| Publication Title | 岡山大学環境理工学部研究報告 |
| Volume | volume14 |
| Issue | issue1 |
| Content Type | Others |
| Author | 岡山大学環境理工学部広報委員会| |
|---|---|
| Published Date | 2009-03-16 |
| Publication Title | 岡山大学環境理工学部研究報告 |
| Volume | volume14 |
| Issue | issue1 |
| Content Type | Others |
| Author | 岡山大学環境理工学部広報委員会| |
|---|---|
| Published Date | 2009-03-16 |
| Publication Title | 岡山大学環境理工学部研究報告 |
| Volume | volume14 |
| Issue | issue1 |
| Content Type | Others |
| Author | 岡山大学環境理工学部広報委員会| |
|---|---|
| Published Date | 2009-03-16 |
| Publication Title | 岡山大学環境理工学部研究報告 |
| Volume | volume14 |
| Issue | issue1 |
| Content Type | Others |
| JaLCDOI | 10.18926/15060 |
|---|---|
| Title Alternative | On the Turkish Verb ol- as an Intransitive Marker |
| FullText URL | 027_229_237.pdf |
| Author | Aydın, ÖZBEK| |
| Publication Title | 岡山大学大学院社会文化科学研究科紀要 |
| Published Date | 2009-03-26 |
| Volume | volume27 |
| Issue | issue1 |
| Start Page | 229 |
| End Page | 237 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120002308017 |
| JaLCDOI | 10.18926/15059 |
|---|---|
| Title Alternative | The State of Discussion On China's Personal Information Protection Act Draft - The Draft's Content and Subject from Now On - |
| FullText URL | 027_213_228.pdf |
| Author | Yasui, Kumi| |
| Publication Title | 岡山大学大学院社会文化科学研究科紀要 |
| Published Date | 2009-03-26 |
| Volume | volume27 |
| Issue | issue1 |
| Start Page | 213 |
| End Page | 228 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120002307934 |
| JaLCDOI | 10.18926/15058 |
|---|---|
| Title Alternative | A Study on the Copyright Waiver in Japan |
| FullText URL | 027_193_212.pdf |
| Author | Tanaka, Hirokazu| |
| Publication Title | 岡山大学大学院社会文化科学研究科紀要 |
| Published Date | 2009-03-26 |
| Volume | volume27 |
| Issue | issue1 |
| Start Page | 193 |
| End Page | 212 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120002307237 |
| JaLCDOI | 10.18926/15057 |
|---|---|
| Title Alternative | Women's Education and Work in Palestine : A Study of Everyday Life under the Conflict |
| FullText URL | 027_173_192.pdf |
| Author | Gamoh, Hiroe| |
| Publication Title | 岡山大学大学院社会文化科学研究科紀要 |
| Published Date | 2009-03-26 |
| Volume | volume27 |
| Issue | issue1 |
| Start Page | 173 |
| End Page | 192 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120002307576 |
| JaLCDOI | 10.18926/15056 |
|---|---|
| FullText URL | 027_161_172.pdf |
| Author | Nasu, Masako| |
| Publication Title | 岡山大学大学院社会文化科学研究科紀要 |
| Published Date | 2009-03-26 |
| Volume | volume27 |
| Issue | issue1 |
| Start Page | 161 |
| End Page | 172 |
| ISSN | 1881-1671 |
| language | English |
| Copyright Holders | 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120002307908 |
| JaLCDOI | 10.18926/15055 |
|---|---|
| Title Alternative | "Die Undurchsichtigkeit" der Welt in Heinrich von Kleists <<Michael Kohlhaas>> |
| FullText URL | 027_143_160.pdf |
| Author | Sugibayashi, Noriaki| |
| Publication Title | 岡山大学大学院社会文化科学研究科紀要 |
| Published Date | 2009-03-26 |
| Volume | volume27 |
| Issue | issue1 |
| Start Page | 143 |
| End Page | 160 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120002307460 |
