result 5764 件
| Author | Iwasaki, Ichiro| |
|---|---|
| Published Date | 1956-09-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume68 |
| Issue | issue9 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/19758 |
|---|---|
| Title Alternative | Separation of paripheral leukocytes by counterflow centrifugation elutriation |
| FullText URL | 059_037_041.pdf |
| Author | Sudo, Michiyasu| Matsubara, Fumie| Araki, Hiroyuki| Kitani, Hikaru| Tanizaki, Yoshiro| |
| Abstract | JE－6B rotor（Beckman）を用いてcounterflow centrifugation elutriationによる末梢血白血球の分離を試み，若干の検討を加えた。1．flow rateが低い場合はリンパ球が大部分を占めたが，flow rateの増加とともに頻度は減少した。2． flow rateの増加とともに，好塩基球の頻度が増加し，9－10ml／minでは頻度のみでなく細胞数の増加も認められた。各fractionにおけるヒスタミン含有量も同様の傾向が認められた。3．好中球のpeakはflow rate 13ml／minであり以後減少を示した。4．最終段階で好酸球が増加傾向を示しChamber内で最も高値を示した。以上の結果よりcounterflow centrifugation elutriationによる末梢血白血球細胞分離は，in vitroにおける実験に有用な手段である可能性が示唆された。 |
| Keywords | 逆流負荷遠心法 (Counterflow centrifugation elutriation) JE－6Bローター (JE-6B rotor) 細胞分離 (Cell separation) 好塩基球 (Basophils) |
| Publication Title | 環境病態研報告 |
| Published Date | 1988-08 |
| Volume | volume59 |
| Start Page | 37 |
| End Page | 41 |
| ISSN | 09133771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002309189 |
| Author | Sunami, Hiroshi| |
|---|---|
| Published Date | 1956-08-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume68 |
| Issue | issue8 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/19710 |
|---|---|
| Title Alternative | Study on anti-allergic action of Terfenadine |
| FullText URL | 058_005_011.pdf |
| Author | Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Kitani, Hikaru| |
| Abstract | 選択的H(1)受容体拮抗薬であるTerfenadineの抗アレルギー作用，特にIgE系反応によるヒスタミン，およびCa ionophore A23187による好中球からのleukotrienes遊離に対する抑制作用を，ヒト末梢血白血球を用いて検討した。１．Terfenadineは，抗ヒトIgE刺激による健康人好塩基球および特異抗原刺激による気管支喘息患者好塩基球からのヒスタミン遊離に対して，全血法でのin vitro添加実験では有意の抑制作用を示さなかった。 2．洗浄白血球法によるin vitro添加実験では，Terfenadineは特異抗原および抗ヒトIgE刺激時の気管支喘息患者好塩基球からのヒスタミン，Ca ionophore A23187刺激時のleukotriene B(4)遊離に対して有意の抑制効果を示した。3．Terfenadineの内服によるin vivoの抑制実験では，IgE系反応による健康人および気管支喘息患者好塩基球からのヒスタミン遊離に対して有意の抑制効果は見られなかったが，特異抗原による皮膚反応に対しては明らかな抑制作用が観察された。以上より，Terfenadineは，組織肥満細胞および組織へと遊走してきた好塩基球に対してはある程度の抑制作用を有しているものと考えられた。 |
| Keywords | 夕一フェナンジン (Terfenadine) lgE系反応 (IgE-mediated reaction) ヒスタミン (histamine) 好塩基球 (basophils) |
| Publication Title | 環境病態研報告 |
| Published Date | 1987-08 |
| Volume | volume58 |
| Start Page | 5 |
| End Page | 11 |
| ISSN | 09133771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002309197 |
| Author | Hanazawa Akitoshi| |
|---|---|
| Published Date | 2009-11-11 |
| Publication Title | Proceedings : Fifth International Workshop on Computational Intelligence & Applications |
| Volume | volume2009 |
| Issue | issue1 |
| Content Type | Conference Paper |
| JaLCDOI | 10.18926/19683 |
|---|---|
| Title Alternative | Studies on anti-allergic actions of tranilast (Rizaben®) |
| FullText URL | 057_042_045.pdf |
| Author | Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Morinaga, Hiroshi| Ohtani, Jun| Kimura, Ikuro| |
| Abstract | 抗アレルギー剤（脱顆粒抑制剤）の1つであるtranilastの肥満細胞の遊離機序に対する抑制作用について検討を加えた。1．抗原刺激時の肥満細胞の(45)Ca uptakeおよびヒスタミン遊離に対して，tranilastは有意の抑制作用を示したが，comp.48/80刺激時にはtranilastの(45)Ca uptake，ヒスタミン遊離に対する抑制作用はほとんどみられなかった。2．phosphatidylserine添加時には，(45)Ca uptakeに対するtranilastの抑制作用は減弱傾向を示し，この傾向はヒスタミン遊離に対する作用に比べより高度であった。3．抗原および抗ヒトIgEによる好塩基球からのヒスタミン遊離に対して，tranilastは明らかな抑制作用を示さなかった。 |
| Keywords | トラニラスト (tranilast) (45)Ca取り込み ((45)Ca uptake) ヒスタミン遊離 (histamine release) 肥満細胞 (mast cell) 好塩基球 (basophils) |
| Publication Title | 環境病態研報告 |
| Published Date | 1986-07 |
| Volume | volume57 |
| Start Page | 42 |
| End Page | 45 |
| ISSN | 09133771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308998 |
| JaLCDOI | 10.18926/19677 |
|---|---|
| FullText URL | Mem_Fac_Eng_OU_33_2_79.pdf |
| Author | Osaka, Akiyoshi| Hayakawa, Satoshi| Koyano Keiko| Tsuru, Kanji| |
| Abstract | A titanium oxide gel was electrochemically prepared on Ti with a cell consisting of Ti as the working electrode, Pt as the counter one, AgCl as the reference one, and an aqueous solution of 0.1 mol/L Ca(NO(3))(2) as the electrolyte solution. The Ti electrode was kept at 9.5V for 1 hr for oxidation and subsequently kept at-3.0V for 10 min (Ca9.5-3.0):calcium ions were expected to be adsorbed at the latter treatment. Other Ti specimen was kept at -3.0V for 10 min (Ca-3.0). Both specimens were found so bioactive as to deposit apatite in 12 hr (Ca9.5-3.0) and in 1 day (Ca-3.0) when soaked in a simulated body fluid (Kokubo solution). Calcium carbonate detected on the surface of Ca9.5-3.0 caused no harmful effects on spontaneous deposition of apatite in the fluid. |
| Publication Title | Memoirs of the Faculty of Engineering, Okayama University |
| Published Date | 1999-04-27 |
| Volume | volume33 |
| Issue | issue2 |
| Start Page | 79 |
| End Page | 84 |
| ISSN | 0475-0071 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002309011 |
| JaLCDOI | 10.18926/19620 |
|---|---|
| Title Alternative | RHEUMATOID ARTHRITIS AND THORN'S TEST |
| FullText URL | 015_029_033.pdf |
| Author | Izumi, Tomokuni| |
| Abstract | In a course of balneotherapy of rheumatoid arthritis, there was no proper standard to judge the therapeutic effect. In this circumstance, Thorn's test and a measurement of red cell sedimentation rate were applied to ten patients with rheumatoid arthritis before and after balneotherpy, and it was found that, although patients before therapy showed a low value of Thorn's test and a faster rate of red cell sedimentation, after released from various symptoms by balneotherapy they had a higher value of Thorn's test and a slower rate of red cell sedimentation. Therefore, these two tests above described may be used as a standard for a judgement of the effect of balneotherapy to patients with rheumatoid arthritis. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1955-03-25 |
| Volume | volume15 |
| Start Page | 29 |
| End Page | 33 |
| ISSN | 0369-7142 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/21510 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002314144 |
| Author | Suga, Masao| |
|---|---|
| Published Date | 1959-04-25 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume71 |
| Issue | issue5-2 |
| Content Type | Journal Article |
| Author | Suga, Masao| |
|---|---|
| Published Date | 1959-04-25 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume71 |
| Issue | issue5-2 |
| Content Type | Journal Article |
| Author | Suga, Masao| |
|---|---|
| Published Date | 1959-04-25 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume71 |
| Issue | issue5-2 |
| Content Type | Journal Article |
| Author | Niguma, Koichiro| |
|---|---|
| Published Date | 1959-04-25 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume71 |
| Issue | issue5-2 |
| Content Type | Journal Article |
| Author | Tawara, Jutaro| |
|---|---|
| Published Date | 1959-04-25 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume71 |
| Issue | issue5-2 |
| Content Type | Journal Article |
| Author | Yamaguchi, Ei| |
|---|---|
| Published Date | 1956-07-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume68 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Michinaka, Tomokatsu| |
|---|---|
| Published Date | 1956-07-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume68 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Michinaka, Tomokatsu| |
|---|---|
| Published Date | 1956-07-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume68 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Yamamoto, Shinro| |
|---|---|
| Published Date | 1956-07-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume68 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Yamamoto, Shinro| |
|---|---|
| Published Date | 1956-07-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume68 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Yamamoto, Shinro| |
|---|---|
| Published Date | 1956-07-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume68 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Yamamoto, Shinro| |
|---|---|
| Published Date | 1956-07-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume68 |
| Issue | issue7 |
| Content Type | Journal Article |
