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Title Alternative A case of duodenal diverticulitis in a patient receiving tocilizumab for rheumatoid arthritis
Author Iwamuro, Masaya| Baba, Yuki| Kawahara, Yoshiro| Okada, Hiroyuki|
Abstract  A Japanese woman was diagnosed with rheumatoid arthritis at the age of 41. At the age of 56, her rheumatoid arthritis worsened and a subcutaneous injection of tocilizumab and oral prednisolone was administered, which led to an improvement of arthritis. At the age of 57, right lower abdominal pain and vomiting suddenly appeared. Abdominal computed tomography showed a parapapillary diverticulum in the descending duodenum. The diverticulum was filled with residue, and an inflammation of the surrounding adipose tissue was observed; no free air was found. The patient was diagnosed with duodenal diverticulitis and treated with antibiotics, which resulted in an uneventful recovery. The maximum value of CRP was 1.88㎎/dL on the third day of hospitalization. Esophagogastroduodenoscopy performed on the 8th day of hospitalization revealed a parapapillary diverticulum with adhesion of pus and redness of the mucosa at the opening of the diverticulum, consistent with diverticulitis. This case highlights that diverticulitis in infrequent areas such as the duodenum may occur in patients who are treated with tocilizumab. In addition, inflammation of diverticulitis may be underestimated because abnormal laboratory values such as those induced by inflammatory reactions are less likely to occur during tocilizumab treatment.
Keywords トシリズマブ(tocilizumab) 十二指腸憩室(duodenal diverticulum) 憩室炎(diverticulitis)
Publication Title Journal of Okayama Medical Association
Published Date 2022-12-01
Volume volume134
Issue issue3
Start Page 166
End Page 170
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.166
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.166
Title Alternative A descriptive analysis for the comparison of the symptoms and severity of coronavirus disease 2019 (COVID-19) in each epidemic period in Okayama City
Author Matsuo, Rumi| Matsumoto, Naomi| Kadowaki, Tomoka| Mitsuhashi, Toshiharu| Takao, Soshi| Yorifuji, Takashi|
Abstract  Japan experienced four major epidemic periods (i.e., the 3rd-6th waves) of COVID-19 from January 2020 to March 2022. A different strain predominated in each period: the wild-type strain, an Alpha variant, a Delta variant, and an Omicron variant were predominant in waves 3, 4, 5, and 6, respectively. In this study, we conducted a descriptive analysis to investigate the differences in symptoms and severity during each epidemic period. We analyzed a total of 31,037 patients with COVID-19 who were reported to the Okayama City Public Health Center between February 1, 2020 and March 31, 2022. We described and compared the proportion of symptoms, the number and proportion of severe COVID-19 cases, and the number and proportion of deaths for each epidemic period. We also compared the proportion of severe COVID-19 cases depending on the number of vaccinations for the 5th and 6th waves.
 Differences in symptoms and severity were observed in each epidemic period. In the 5th and 6th waves, the results suggested that vaccination had a preventive effect against severe COVID-19.
Keywords 新型コロナウイルス感染症(coronavirus disease 2019 ) COVID-19 症状(symptom) 重症度(severity) ワクチン(vaccination)
Publication Title Journal of Okayama Medical Association
Published Date 2022-12-01
Volume volume134
Issue issue3
Start Page 160
End Page 165
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.160
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.160
Title Alternative Endoscopic and exoscopic neurosurgery
Author Date, Isao|
Keywords 神経内視鏡 神経外視鏡 脳神経外科 heads-up surgery
Publication Title Journal of Okayama Medical Association
Published Date 2022-12-01
Volume volume134
Issue issue3
Start Page 152
End Page 159
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.152
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.152
Title Alternative Non-vascular interventional radiology for lung cancer
Author Hiraki, Takao|
Keywords 肺癌(lung cancer) インターベンショナルラジオロジー(interventional radiology) 非血管系(non-vascular)
Publication Title Journal of Okayama Medical Association
Published Date 2022-12-01
Volume volume134
Issue issue3
Start Page 145
End Page 151
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.145
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.145
Title Alternative The 2021 Incentive Award of the Okayama Medical Association in Cancer Research (2021 Hayashibara Prize and Yamada Prize)
Author Kakiuchi, Yoshihiko|
Publication Title Journal of Okayama Medical Association
Published Date 2022-12-01
Volume volume134
Issue issue3
Start Page 142
End Page 144
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.142
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.142
Title Alternative The 2021 Incentive Award of the Okayama Medical Association in Neuroscience (2021 Niimi Prize)
Author Nojima, Kojiro|
Publication Title Journal of Okayama Medical Association
Published Date 2022-12-01
Volume volume134
Issue issue3
Start Page 139
End Page 141
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.139
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.139
Title Alternative The 2021 Incentive Award of the Okayama Medical Association in General Medical Science (2021 Yuuki Prize)
Author Sun, Cuiming|
Publication Title Journal of Okayama Medical Association
Published Date 2022-12-01
Volume volume134
Issue issue3
Start Page 136
End Page 138
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.136
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.136
Title Alternative The 2021 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2021 Sunada Prize)
Author Senoo, Satoru|
Publication Title Journal of Okayama Medical Association
Published Date 2022-12-01
Volume volume134
Issue issue3
Start Page 133
End Page 135
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.133
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.133
Title Alternative The 121th General Assembly of the Okayama Medical Association
FullText URL 134_126.pdf
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 126
End Page 132
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.126
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.126
Title Alternative The 34th Annual Meeting of the Japanese Society of Cartilage Metabolism
FullText URL 134_125.pdf
Author Ozaki, Toshifumi|
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 125
End Page 125
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.125
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.125
Title Alternative Biobank and residual sample use for medical research
FullText URL 134_119.pdf
Author Yamamoto, Hideki| Hirasawa, Akira|
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 119
End Page 122
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.119
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.119
Title Alternative Kibichuo Town is the first National Strategic Special Zone for innovative business collaboration in Japan: The role of universities in achieving regulatory reform with a vision toward a Digital Garden City Nation
FullText URL 134_115.pdf
Author Nasu, Yasutomo| Maki, Jota| Sakurai, Jun| Masuyama, Hisashi| Maeda, Yoshinobu|
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 115
End Page 118
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.115
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.115
Title Alternative The role of legal medicine in mass disaster : A report on the activity of the Department of Legal Medicine of Okayama University for the postmortem examination following the Great East Japan Earthquake
FullText URL 134_108.pdf
Author Miura, Masanobu| Miyaishi, Satoru| Taniguchi, Kaori| Yamasaki, Yukie| Kobayashi, Chie| Takei, Sella| Aoki, Yasuhiro|
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 108
End Page 114
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.108
language English
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.108
Title Alternative Drug interaction (54. Drug interaction in the process of absorption and excretion of anticancer drugs)
FullText URL 134_102.pdf
Author Danzako, Minato| Esumi, Satoru| Zamami, Yoshito|
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 102
End Page 107
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.102
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.102
Title Alternative Autoimmune bullous diseases : Pemphigus and pemphigoid
FullText URL 134_99.pdf
Author Hirai, Yoji|
Keywords 自己免疫性水疱症 天疱瘡 類天疱瘡
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 99
End Page 101
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.99
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.99
FullText URL fulltext20230425-01.pdf
Author Takemoto, Fumiko| Uchida-Fukuhara, Yoko| Kamioka, Hiroshi| Okamura, Hirohiko| Ikegame, Mika|
Keywords Cell alignment Cell division Mechanical stress Migration Osteoblasts
Note The version of record of this article, first published in Anatomical Science International, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12565-023-00716-8|
Published Date 2023-04-06
Publication Title Anatomical Science International
Publisher Springer Science and Business Media LLC
ISSN 1447-6959
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37022568
DOI 10.1007/s12565-023-00716-8
Web of Science KeyUT 000964049600002
Related Url isVersionOf https://doi.org/10.1007/s12565-023-00716-8
Title Alternative Eosinophilic granulomatosis with polyangiitis
FullText URL 134_95.pdf
Author Matsumoto, Yoshinori|
Keywords ANCA関連血管炎 好酸球性多発血管炎性肉芽腫症 EGPA
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 95
End Page 98
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.95
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.95
Title Alternative Vitamin D-resistant rickets/osteomalacia: FGF23-related hypophosphatemic rickets/osteomalacia
FullText URL 134_92.pdf
Author Fujisawa, Satoshi| Inagaki, Kenichi| Wada, Jun|
Keywords FGF23 くる病 骨軟化症 低リン血症
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 92
End Page 94
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.92
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.92
Title Alternative Clusters of coronavirus disease 2019 in medical institutions and elderly care facilities in Okayama Prefecture
FullText URL 134_86.pdf
Author Kadowaki, Tomoka| Irie, Saori| Takahashi, Yukari| Yakushiji, Hiromasa| Takao, Soshi| Yorifuji, Takashi|
Abstract  Coronavirus disease 2019 has spread worldwide and has yet to be contained. The Japanese government has taken measures against the occurrence of clusters. However, there has little evaluation of the occurrence of the clusters and their changes. Therefore, we investigated the occurrence of the clusters in medical institutions and elderly care facilities in Okayama Prefecture.
 We compared the characteristics of the clusters that occurred in each of the wave between October 21, 2020, and September 30, 2021, by using the data published that interval. As a case study, we also evaluated the characteristics of positive patients at a medical institution over where a cluster occurred in case the fourth wave.
 The overall number of cluster outbreaks decreased with the spread of vaccination. In the fourth wave, there was a period in which the vaccination of staff members at medical institutions became widespread, while patients or facility users were unvaccinated, resulting in a longer convergence period and an increase in the number of positive cases among patients relative to the number of staff members.
 The impact of the spread of vaccination and the duration of immunity acquired after vaccination on the occurrence of clusters should be closely monitored in the future.
Keywords 新型コロナウイルス感染症 (coronavirus disease 2019) 岡山県 (Okayama Prefecture) クラスター (cluster) ワクチン接種 (vaccination) 疫学 (epidemiology)
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 86
End Page 91
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.86
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.86
Title Alternative Multicenter clinical trials that take cardiovascular care one step further
FullText URL 134_79.pdf
Author Ito, Hiroshi|
Keywords 多施設共同臨床試験 (multicentertrial) 遠隔診療 (remote medicalcare) 動脈硬化性心血管疾患 (atherosclerotic cardiovascular disease) 心不全 (heart failure) 糖尿病 (diabetes mellitus)
Publication Title Journal of Okayama Medical Association
Published Date 2022-08-01
Volume volume134
Issue issue2
Start Page 79
End Page 85
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.79
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.79