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FullText URL K0005687_abstract_review.pdf K0005687_summary.pdf K0005687_fulltext.pdf K0005687_figs.pdf
Author Kochi, Mariko|
Published Date 2018-03-23
Content Type Thesis or Dissertation
Grant Number 甲第5687号
Granted Date 2018-03-23
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
JaLCDOI 10.18926/AMO/55860
FullText URL 72_2_185.pdf
Author Morizane, Shin| Sugimoto, Saeko| Motoki, Takayuki| Katayama, Norihisa| Omori, Masako| Iwatsuki, Keiji|
Abstract Psoriasis is a common chronic inflammatory skin disorder that is characterized by scaly, erythematous, sharply demarcated plaques. The treatment for psoriasis has dramatically changed over the last 10 years with the introduction of biologics. However, the risk of cancer induced by biologics for psoriasis has not been fully analyzed, since these agents have such a short history of use. Here we report the case of a 74-year-old woman with psoriasis vulgaris and psoriatic arthritis complicated by breast cancer after systemic treatments including etretinate, cyclosporine, methotrexate, adalimumab, and ustekinumab.
Keywords psoriasis systemic therapy biologics malignancy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2018-04
Volume volume72
Issue issue2
Publisher Okayama University Medical School
Start Page 185
End Page 187
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2018 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 29674768
JaLCDOI 10.18926/AMO/55854
FullText URL 72_2_137.pdf
Author Takahashi, Yuko| Shien, Tadahiko| Sakamoto, Ai| Tsuyumu, Yuko| Yoshioka, Ryo| Uno, Maya| Hatono, Minami| Kochi, Mariko| Kawada, Kengo| Tsukioki, Takahiro| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Matsuoka, Junji| Nakatsuka, Mikiya| Doihara, Hiroyoshi|
Abstract Adverse effects on fertility are a significant problem for premenopausal breast cancer patients. Since April 2009, we have been referring young patients for fertility counseling provided by a multidisciplinary team. Here we evaluated the efficacy and safety of our current fertility preservation approach. We retrospectively analyzed the cases of 277 patients < 45 years old at diagnosis, which was made between 2009 and 2016. Seventy-two (26%) patients received fertility counseling. Seventeen (6%) of the 277 patients decided to preserve their fertility before starting adjuvant systemic therapy. Six (35%) patients underwent oocyte cryopreservation, and 11 (65%) married patients opted for embryo cryopreservation. There were no pregnancies among the patients undergoing oocyte cryopreservation, whereas 3 (27%) of the patients who opted for embryo cryopreservation became pregnant. Two (12%) patients stopped endocrine therapy after 2 years in an effort to become pregnant, but their breast cancers recurred. Though the problem of fertility loss for breast cancer patients is important and we should assess the infertility risk for all patients, we should also consider the prognosis. In June 2016, we launched a prospective multicenter cohort study to evaluate the efficacy and safety of fertility preservation in greater detail.
Keywords fertility preservation multidisciplinary breast cancer young patients
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2018-04
Volume volume72
Issue issue2
Publisher Okayama University Medical School
Start Page 137
End Page 142
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2018 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 29674762
FullText URL K0005600_other1.pdf
Author Takeda, Tatsuaki| Yamamoto, Hiromasa| Kanzaki, Hirotaka| Suzawa, Ken| Yoshioka, Takahiro| Tomida, Shuta| Cui, Xiaojiang| Murali, Ramachandran| Namba, Kei| Sato, Hiroki| Torigoe, Hidejiro| Watanabe, Mototsugu| Shien, Kazuhiko| Soh, Junichi| Asano, Hiroaki| Tsukuda, Kazunori| Kitamura, Yoshihisa| Miyoshi, Shinichiro| Sendo, Toshiaki| Toyooka, Shinichi|
Note 学位審査副論文|
Published Date 2017-02-03
Publication Title PLoS One
Volume volume12
Issue issue2
Publisher Public Library of Science
Start Page e0171356
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version publisher
PubMed ID 28158234
DOI 10.1371/journal.pone.0171356
Web of Science KeyUT 000396161700064
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0171356 isPartOf http://ousar.lib.okayama-u.ac.jp/55525
FullText URL K0005596_other1.pdf
Author Thar Htet San| Fujisawa, Masayoshi| Fushimi, Soichiro| Soe, Lamin| Ngu Wah Min| Yoshimura, Teizo| Ohara, Toshiaki| Myint Myint Yee| Oda, Shinsuke| Matsukawa , Akihiro|
Keywords Breast cancer molecular subtypes Ki-67 expression Myanmar
Note 学位審査副論文|
Published Date 2017-06-25
Publication Title Asian Pacific journal of cancer prevention
Volume volume18
Issue issue6
Publisher Asian Pacific Organization for Cancer Prevention
Start Page 1617
End Page 1621
ISSN 1513-7368
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version publisher
PubMed ID 28670879
DOI 10.22034/APJCP.2017.18.6.1617
Related Url isVersionOf https://doi.org/10.22034/APJCP.2017.18.6.1617 isPartOf http://ousar.lib.okayama-u.ac.jp/55521
FullText URL K0005596_abstract_review.pdf K0005596_summary.pdf K0005596_fulltext.pdf
Author Thar Htet San|
Published Date 2017-09-29
Content Type Thesis or Dissertation
Grant Number 甲第5596号
Granted Date 2017-09-29
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL BreastCancer_24_4_593.pdf BreastCancer_24_4_593_tbl_fig.pdf
Author Saiga, Miho| Taira, Naruto| Kimata, Yoshihiro| Watanabe, Satoko| Mukai, Yuko| Shimozuma, Kojiro| Mizoo, Taeko| Nogami, Tomohiro| Iwamoto, Takayuki| Motoki, Takayuki| Shien, Tadahiko| Matsuoka, Junji| Doihara, Hiroyoshi|
Keywords BREAST-Q Breast cancer Breast reconstruction Health-related quality of life Satisfaction
Published Date 2017-03
Publication Title Breast Cancer
Volume volume24
Issue issue2
Publisher Japanese Breast Cancer Society
Start Page 288
End Page 298
ISSN 1340-6868
NCID AA1103354X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version author
PubMed ID 27179527
DOI 10.1007/s12282-016-0703-6
Web of Science KeyUT 000395524900012
Related Url isVerionOf https://doi.org/10.1007/s12282-016-0703-6
FullText URL BreastCancer_24_4_593.pdf BreastCancer_24_4_593_tbl_fig.pdf
Author Yatake, Hidetoshi| Sawai, Yuka| Nishi, Toshio| Nakano, Yoshiaki| Nishimae, Ayaka| Katsuda, Toshizo| Yabunaka, Koichi| Takeda, Yoshihiro| Inaji, Hideo|
Keywords Breast cancer Direct methods Mammography Mask methods Stereotactic vacuum assisted biopsy
Published Date 2017-07
Publication Title Breast Cancer
Volume volume24
Issue issue4
Publisher Japanese Breast Cancer Society
Start Page 593
End Page 600
ISSN 1340-6868
NCID AA1103354X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
File Version author
PubMed ID 27878446
DOI 10.1007/s12282-016-0743-y
Web of Science KeyUT 000404221100015
Related Url https://doi.org/10.1007/s12282-016-0743-y
Title Alternative The 2016 Incentive Award of the Okayama Medical Association in Cancer Research (2016 Hayashibara Prize and Yamada Prize)
FullText URL 129_89.pdf
Author 藤田 洋史|
Publication Title Journal of Okayama Medical Association
Published Date 2017-08-01
Volume volume129
Issue issue2
Start Page 89
End Page 91
ISSN 0030-1558
Related Url https://doi.org/10.4044/joma.129.89
language Japanese
Copyright Holders Copyright (c) 2017 岡山医学会
File Version publisher
DOI 10.4044/joma.129.89
NAID 130006039368
JaLCDOI 10.18926/AMO/55210
FullText URL 71_3_259.pdf
Author Kawana, Shinichi| Yamamoto, Hiromasa| Maki, Yuho| Sugimoto, Seiichiro| Toyooka, Shinichi| Miyoshi, Shinichiro|
Abstract  Primary sternal chondrosarcoma is a rare malignant tumor that is refractory to chemotherapy and radiation. Effective therapy is radical resection of the tumor. We present two patients with primary sternal chondrosarcoma who underwent a radical resection of the lower half of the sternum and bilateral ribs, followed by reconstruction with 2 sheets of polypropylene mesh layered orthogonally. The patients have maintained almost the same pulmonary function as preoperative values, with stability of the chest wall. Although there are various ways to reconstruct the anterior chest wall, reconstruction with polypropylene mesh layered orthogonally is an easy-to-use and sufficient method.
Keywords chondrosarcoma sternum reconstruction polypropylene mesh
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2017-06
Volume volume71
Issue issue3
Publisher Okayama University Medical School
Start Page 259
End Page 262
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28655947
JaLCDOI 10.18926/AMO/55206
FullText URL 71_3_233.pdf
Author Shimoyama, Kyoko| Osako, Tomo| Mitsuhashi, Toshiharu| Akiyama, Futoshi| Iwase, Takuji|
Abstract Ductal carcinoma in situ (DCIS) of the breast has no potential to metastasize, but over 20% of cases preoperatively diagnosed as DCIS are upstaged on final pathology. The rates of upstaging and the predictors for invasion on final pathology were evaluated. For 240 primary breast cancers, radiological findings on mammography, ultrasonography, and magnetic resonance imaging were investigated along with pathological and clinical information. Univariate and multivariate analyses were performed to identify predictors of potential invasion. Of the 240 breast cancers, 68 (28.3%) showed invasion on final pathology, and 5 (2.5%) had sentinel node metastasis. The multivariate analysis identified five independent predictors: non-mass lesions >2.4 cm on ultrasonography (odds ratio [OR] 2.84, 95% confidence interval [CI] 1.02-7.95, p=0.047), comedo-type histology (OR 6.89, 95% CI 1.89-25.08, p<0.01), solid-type histology (OR 7.97, 95% CI 2.08-30.49, p<0.01), palpable mass (OR 2.63, 95% CI 1.05-6.64, p=0.04), and bloody nipple discharge (OR 4.61, 95% CI 1.20-17.66, p=0.02). These five predictors were associated with invasion on final pathology and may help select candidates for sentinel node biopsy.
Keywords breast cancer DCIS breast needle biopsy imaging examination sentinel node biopsy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-06
Volume volume71
Issue issue3
Publisher Okayama University Medical School
Start Page 233
End Page 240
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28655943
FullText URL K0005517_abstract_review.pdf K0005517_fulltext.pdf K0005517_summary.pdf
Author Matsui, Miyuki|
Published Date 2017-03-24
Content Type Thesis or Dissertation
Grant Number 甲第5517号
Granted Date 2017-03-24
Thesis Type Doctor of Philosophy in Nursing Science
Grantor 岡山大学
language Japanese
FullText URL K0005471_abstract_review.pdf K0005471_summary.pdf K0005471_fulltext.pdf
Author Miyoshi, Yuichiro|
Published Date 2017-03-24
Content Type Thesis or Dissertation
Grant Number 甲第5471号
Granted Date 2017-03-24
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL K0005470_abstract_review.pdf K0005470_summary.pdf K0005470_fulltext.pdf
Author Hara, Akio|
Published Date 2017-03-24
Content Type Thesis or Dissertation
Grant Number 甲第5470号
Granted Date 2017-03-24
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
JaLCDOI 10.18926/AMO/54978
FullText URL 71_2_105.pdf
Author Shinya, Takayoshi| Tanaka, Takashi| Soh, Junichi| Matsushita, Toshi| Sato, Shuhei| Toyooka, Shinichi| Yoshino, Tadashi| Miyoshi, Shinichiro| Kanazawa, Susumu|
Abstract We retrospectively assessed the dual-time-point (DTP) F-18 FDG PET/CT findings of thymic epithelial neoplasms (TENs) and investigated the diagnostic capacity of PET/CT compared to that of CT for predicting carcinoma. We calculated the ratio of the standardized uptake value of the tumor and that of the aortic arch (T/M ratio) for both the 90-min early scan and the 2-h delayed scan in 56 TEN patients. We used a multivariate logistic regression (MLR) analysis to estimate the CT features of carcinoma. We compared the diagnostic capacities of PET/CT and chest CT using receiver operating characteristic (ROC) analyses. The ROC curve revealed that the appropriate cut-off T/M ratio value for the highest accuracy was 2.39 with 75.0% accuracy. The area under the curve (AUC) was 0.855. The statistical analyses for DTP scans of 35 TEN patients demonstrated 74.3% accuracy and 0.838 AUC for the early scan versus 82.9% and 0.825 for the delayed scan. The MLR analysis indicated that mediastinal fat infiltration was a predictor of carcinoma. The ROC curve obtained for the model yielded an AUC of 0.853. Delayed scanning could improve the diagnostic capacity for carcinoma. The T/M ratio and mediastinal fat infiltration are predictive of carcinoma with moderate diagnostic accuracy.
Keywords thymic epithelial neoplasm thymic carcinoma thymoma dual-time-point PET/CT chest CT
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2017-04
Volume volume71
Issue issue2
Publisher Okayama University Medical School
Start Page 105
End Page 112
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2017 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28420891
Title Alternative The 69th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery
FullText URL 129_63.pdf
Author Miyoshi, Shinichiro|
Publication Title Journal of Okayama Medical Association
Published Date 2017-04-03
Volume volume129
Issue issue1
Start Page 63
End Page 64
ISSN 0030-1558
language Japanese
Copyright Holders Copyright (c) 2017 岡山医学会
File Version publisher
DOI 10.4044/joma.129.63
NAID 130005632076
Title Alternative Precision Medicine
FullText URL 129_59.pdf
Author Tomida, Shuta| Toyooka, Shinichi|
Publication Title Journal of Okayama Medical Association
Published Date 2017-04-03
Volume volume129
Issue issue1
Start Page 59
End Page 60
ISSN 0030-1558
language Japanese
Copyright Holders Copyright (c) 2017 岡山医学会
File Version publisher
DOI 10.4044/joma.129.59
NAID 130005632074
Author Yasuda, Yukiko| Sakai, Akiko| Ito, Sachio| Sasai, Kaori| Yamamoto, Hiromasa| Matsubara, Nagahide| Ouchida, Mamoru| Katayama, Hiroshi| Shimizu, Kenji|
Published Date 2017-02
Publication Title Acta Medica Okayama
Volume volume71
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/AMO/54826
JaLCDOI 10.18926/AMO/54816
FullText URL 70_6_507.pdf
Author Torigoe, Hidejiro| Toyooka, Shinichi| Yamamoto, Hiromasa| Soh, Junichi| Miyoshi, Shinichiro|
Abstract We present the case of a 65-year-old Japanese man diagnosed with chronic empyema (without a bronchopleural fistula) that occurred 7 months after he underwent an extrapleural pneumonectomy for right malignant pleural mesothelioma (MPM). Following thoracic drainage and irrigation for 1 month, we performed surgery by a thoracoscopic approach, in light of his general condition. We performed debridement and removal of the Gore-Tex polytetrafluoroethylene (PTFE) patch that had been used for the reconstruction of the diaphragm and the pericardium. The empyema had not relapsed when he died from recurrence of the MPM at 4 months after the thoracoscopic surgery. This patientʼs case suggests that thoracoscopic debridement and patch removal can be a therapeutic option for not only early-stage (exudative or fibrinopurulent) empyema but also late-stage (organized and chronic) empyema without a bronchopleural fistula, particularly for patients in poor general condition.
Keywords empyema chronic extrapleural pneumonectomy thoracoscopic debridement patch removal
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2016-12
Volume volume70
Issue issue6
Publisher Okayama University Medical School
Start Page 507
End Page 510
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2016 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 28003678
Author Ono, Miho|
Published Date 2016-09-30
Content Type Thesis or Dissertation