骨髓体外組織培養法によるアドレナリン，コーチゾン，ACTHの白血球系特に好酸球に及ぼす影響に関する研究―特に好酸球減少の機転を中心として― 第一編 家兎大腿骨骨髄培養に於けるアドレナリン，コーチゾン，ACTHの白血球系特に好酸球に及ぼす影響に就て

Using the tissue culture of the bone marrow, I have studied the mechanisms of adrenalin cortisone and ACTH eosinopenia in the bone marrow. The results are as follows: (1) For the mechanism in the bone marrow, adrenalin eosinopenia is based on checking or migratory impossibility of the eosinophil to the bone marrow sinus, and not on the reduced production of the bone marrow. (2) Cortisone eosinopenia is caused from the hypofunction of the eosinophil or from developmental disturbance of the bone marrow parenchyma. (3) Adrenalin or cortisone eosinopenia greatly depends upon its quantitative proportion in the medium. (4) For the direct effect on the bone marrow, ACTH causes the hyperfunction of the eosinophil in a paticular manner but has no influence upon the cell division of the eosinophil. (5) The pseudoeosinophil is free from hypofunctional action and developmental disturbance of adrenalin, cortisone, or ACTH, except the case of high concentration of adrenalin as well as cortisone.