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FullText URL fulltext20230418-02.pdf
Author Watanabe, Takaichi| Oe, Emiho| Mizutani, Yuna| Ono, Tsutomu|
Published Date 2023-03-23
Publication Title Soft Matter
Volume volume19
Issue issue15
Publisher Royal Society of Chemistry
Start Page 2745
End Page 2754
ISSN 1744-683X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Royal Society of Chemistry 2023
File Version publisher
PubMed ID 36987711
DOI 10.1039/d3sm00112a
Web of Science KeyUT 000959187800001
Related Url isVersionOf https://doi.org/10.1039/d3sm00112a
FullText URL fulltext20230414-01.pdf
Author 今津 勝紀|
Published Date 2023-03
Publication Title 島根県古代文化センター研究論集
Volume volume30
Start Page 221
End Page 238
language Japanese
File Version author
FullText URL fulltext20230418-01.pdf
Author Hirano, Masaki| Muto, Yuki| Kuroda, Masahiro| Fujiwara, Yuta| Sasaki, Tomoaki| Kuroda, Kazuhiro| Kamizaki, Ryo| Imajoh, Satoshi| Tanabe, Yoshinori| E. Al-Hammad, Wlla| Nakamitsu, Yuki| Shimizu, Yudai| Sugimoto, Kohei| Oita, Masataka| Sugianto, Irfan| O. Bamgbose, Babatunde|
Keywords MAVRIC SL metal artifacts implant phantom MRI
Published Date 2023-1-24
Publication Title Experimental and Therapeutic Medicine
Volume volume25
Issue issue3
Publisher Spandidos Publications
Start Page 109
ISSN 1792-0981
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Hirano et al.
File Version publisher
PubMed ID 36793326
DOI 10.3892/etm.2023.11808
Web of Science KeyUT 000948969100001
Related Url isVersionOf https://doi.org/10.3892/etm.2023.11808
FullText URL fulltext.pdf
Author Sasaki, Ryo| Matsuoka, Chika| Yamashita, Toru| Kinomura, Masaru| Abe, Koji|
Keywords dialysis disequilibrium syndrome involuntary movement renal failure myoclonus hemodialysis
Published Date 2023-03-13
Publication Title Cureus
Volume volume15
Issue issue3
Publisher CUREUS INC
Start Page e36104
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Sasaki et al.
File Version publisher
DOI 10.7759/cureus.36104
Web of Science KeyUT 000957269900011
Related Url isVersionOf https://doi.org/10.7759/cureus.36104
FullText URL fulltext.pdf
Author Sako, Hidefumi| Omori, Kazuhiro| Nakayama, Masaaki| Mandai, Hiroki| Ideguchi, Hidetaka| Yoshimura-Nakagawa, Saki| Sakaida, Kyosuke| Nagata-Kamei, Chiaki| Kobayashi, Hiroya| Ishii, Satoki| Ono, Mitsuaki| Ibaragi, Soichiro| Yamamoto, Tadashi| Suga, Seiji| Takashiba, Shogo|
Keywords synthetic (+)-terrein periodontitis TNF-α
Published Date 2023-03-03
Publication Title Journal of Fungi
Volume volume9
Issue issue3
Publisher MDPI
Start Page 314
ISSN 2309-608X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 36983482
DOI 10.3390/jof9030314
Web of Science KeyUT 000960078500001
Related Url isVersionOf https://doi.org/10.3390/jof9030314
FullText URL fulltext.pdf
Author Gathinji, Peter Kiiru| Yousofi, Zabiallah| Akada, Karin| Wali, Ajmal| Nishino, Naoki|
Keywords airborne dust blood metabolites Jersey cows microbiota milk
Published Date 2023-03-16
Publication Title Veterinary Sciences
Volume volume10
Issue issue3
Publisher MDPI
Start Page 226
ISSN 2306-7381
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 36977265
DOI 10.3390/vetsci10030226
Web of Science KeyUT 000960149500001
Related Url isVersionOf https://doi.org/10.3390/vetsci10030226
JaLCDOI 10.18926/AMO/65155
FullText URL 77_2_227.pdf
Author Obayashi, Atsuto| Aoki, Kazuma| Wada, Tadayoshi| Furuie, Hiromi | Kuraoka, Kazuya| Hamamoto, Takao| Tatsukawa, Takaharu|
Abstract We describe the use of the tyrosine kinase inhibitor lenvatinib in a patient with brain tumor metastases from anaplastic thyroid carcinoma (ATC). A 52-year-old Japanese male presented with consciousness loss. Imaging revealed a thyroid tumor and multiple brain lesions. After the brain tumor’s resection, pathology results provided the diagnosis of ATC. Total thyroidectomy was performed, followed by whole-brain irradiation. Additional brain lesions later developed, and lenvatinib therapy was initiated with no remarkable complications. However, the treatment effects were limited, and the patient died 2 months after starting lenvatinib, 202 days after the initial brain surgery. Relevant literature is discussed.
Keywords anaplastic thyroid carcinoma brain metastasis lenvatinib
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 227
End Page 232
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094963
Web of Science KeyUT 000982563800006
JaLCDOI 10.18926/AMO/65154
FullText URL 77_2_221.pdf
Author Iriyoshi, Hiroki| Sada, Ken-ei| Miyauchi, Atsushi| Yamamoto, Hirotaka| Hashimoto, Daisuke| Nojima, Shigeru| Yamanaka, Shingo| Kawamura, Masafumi| Oka, Satoshi|
Abstract Several previous case reports have shown that patients with immunoglobulin D (IgD) multiple myeloma (MM) can be withdrawn from hemodialysis, however, the characteristics that can predict withdrawal in these patients have not yet been elucidated. A 57-year-old Japanese woman required hemodialysis because of renal dysfunction due to IgD-λ and Bence Jones protein-λ MM. Bortezomib-based chemotherapy nine days after admission led to her withdrawal from hemodialysis on Day 50. In our case-based review, younger age and early initiation of bortezomib-based chemotherapy emerged as possible predictors of successful hemodialysis withdrawal.
Keywords IgD-type multiple myeloma acute renal dysfunction urinary protein hemodialysis bortezomib
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 221
End Page 225
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094962
Web of Science KeyUT 000982563800005
JaLCDOI 10.18926/AMO/65153
FullText URL 77_2_215.pdf
Author Washio, Kana| Tamefusa, Kosuke| Ochi, Motoharu| Kanamitsu, Kiichiro| Ishida, Hisashi| Fujiwara, Kaori| Nishida, Kenji| Tamai, Kei| Washio, Yosuke| Yoshimoto, Junko| Noda, Takuo| Tsukahara, Hirokazu|
Abstract Among patients with transient abnormal myelopoiesis (TAM) associated with Down syndrome, approximately 20% die within 6 months from multiorgan failure, especially liver fibrosis. We experienced three children with TAM who had low white blood cell counts but increased bilirubin levels. Here, we discuss the detailed clinical courses of these patients, including the pathological findings of liver biopsies. Our cases, together with previous literature, suggest that liver biopsy can be performed safely and provides useful information, especially regarding disease activities, and that low-dose cytarabine is a reasonable option to prevent early death in TAM patients with liver dysfunction.
Keywords liver biopsy transient abnormal myelopoiesis Down syndrome low-dose cytarabine
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 215
End Page 220
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094961
Web of Science KeyUT 000982563800004
JaLCDOI 10.18926/AMO/65152
FullText URL 77_2_209.pdf
Author Sakamoto, Masaki| Teraishi, Fuminori| Shigeyasu Kunitoshi| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
Abstract A 70-year-old male with anal pain and fever was diagnosed with rectal cancer perforation and abscess in the right gluteus maximus (GM) muscle. He underwent a transverse colon colostomy followed by preoperative capecitabine+oxaliplatin. Some local control was achieved but a residual abscess was observed in the right GM muscle. To secure circumferential resection margin by tumor reduction, he received chemoradiotherapy as total neoadjuvant therapy (TNT) and underwent laparoscopic abdominoperineal resection, D3 lymph node dissection, combined coccyx resection, and partial resection of the right GM muscle. The skin defect and pelvic dead space were filled with a right lateral vastus lateral great muscle flap. Histopathologically, the resected specimen showed no tumor cells in the primary tumor or lymph nodes, indicating a pathological complete response (pCR). This case suggests that TNT might improve the R0 resection and pCR rates and overall survival.
Keywords locally advanced rectal cancer total neoadjuvant therapy lateral vastus lateral great muscle flap
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 209
End Page 213
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094960
Web of Science KeyUT 000982563800003
JaLCDOI 10.18926/AMO/65151
FullText URL 77_2_203.pdf
Author Fukushima, Shinnosuke| Hagiya, Hideharu| Iio, Koji| Honda, Hiroyuki| Ishida, Tomoharu| Nagaoka, Hirokazu| Hasegawa, Kou| Otsuka, Fumio|
Abstract Granulicatella species are rare, nutritionally variant streptococci that cause infective endocarditis. Their clinical and microbiological characteristics remain unknown. We reviewed five years of Granulicatella cases in our hospital database (Jan 2017-Jun 2022), finding 6 Granulicatella adiacens cases and 1 Granulicatella elegans case. Clinical backgrounds and bacteremia sources were diverse; 3 cases developed polymicrobial bacteremia. Antimicrobial testing showed non-susceptibility to penicillin G in 4 of 7 cases (57.1%), and high susceptibility to carbapenems and vancomycin in all cases. Determining optimal antibiotic therapy for Granulicatella infections is vital in this era of antimicrobial resistance.
Keywords antimicrobial resistance bacteremia Granulicatella species nutritionally variant streptococci
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 203
End Page 207
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094959
Web of Science KeyUT 000982563800002
JaLCDOI 10.18926/AMO/65150
FullText URL 77_2_199.pdf
Author Nagano, Tomohiro| Hosokawa, Shinobu| Miyahara, Hideaki| Yamada, Kotaro| Umeno, Takayuki| Kano, Hirohisa| Kayatani, Hiroe| Sakugawa, Makoto| Takehisa, Yasushi| Takenaka, Tadasu| Takeuchi, Makoto| Bessho, Akihiro|
Abstract Meningitis-retention syndrome (MRS) is the combination of aseptic meningitis and acute urinary retention that occurs in the absence of other neurological diseases. The cause(s) of MRS remain unclear. A 57-year-old Japanese woman was referred to our hospital for the evaluation of persistent fever and headache. The fever’s cause was initially unclear, but the presence of urinary retention raised concern about possible aseptic meningitis despite no physical indications of meningeal irritation. Only typical cases of MRS have been reported thus far to our knowledge, and it is important that clinicians are aware of MRS when it presents in this atypical form.
Keywords meningitis-retention syndrome aseptic meningitis acute urinary retention
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 199
End Page 201
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094958
Web of Science KeyUT 000982503800010
JaLCDOI 10.18926/AMO/65149
FullText URL 77_2_193.pdf
Author Ikeda, Tomohiro| Noma, Kazuhiro| Okura, Kazuki| Katayama, Sho| Takahashi, Yusuke| Maeda, Naoaki| Tanabe, Shunsuke| Wakita, Akiyuki| Hamada, Masanori| Fujiwara, Toshiyoshi| Senda, Masuo|
Abstract This retrospective study aimed to investigate the validity of a 30-sec chair stand test (CS-30) as a simple test to assess exercise tolerance and clinical outcomes in 53 Japanese patients with esophageal cancer. There was a strong correlation between the results of CS-30 and the 6-min walk test (6MWT), the gold standard for assessing exercise tolerance (r=0.759). Furthermore, fewer patients whose CS-30 score was greater than 16 (the cutoff value defined based on 6MWT) experienced pneumonia in their postoperative course. These results suggest that exercise tolerance could be assessed using CS-30, and its cutoff value may be useful in predicting postoperative pneumonia risk.
Keywords esophageal cancer exercise tolerance rehabilitation
Amo Type Short Communication
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 193
End Page 197
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094957
Web of Science KeyUT 000982503800009
JaLCDOI 10.18926/AMO/65148
FullText URL 77_2_185.pdf
Author Sugihara, Akiko| Okada, Ayumi| Horiuchi, Makiko| Yabe, Mayumi| Shigeyasu, Yoshie| Fujii, Chikako| Tanaka, Chie| Yorifuji, Takashi| Tsukahara, Hirokazu|
Abstract Psychosomatic disorders are influenced by psychosocial factors such as interpersonal relationships. Coping behaviors, especially in frustrating situations, reflect a patient’s ability to cope with stress, and it is important to assess these behaviors for the treatment of psychosomatic diseases. This study aimed to clarify the interpersonal relationships and coping behaviors of pediatric patients with psychosomatic diseases during frustrating situations simulated using the Rosenzweig Picture-Frustration study. This retrospective study included 126 patients (41 male, 85 female) with an average age of 12.9 (6-16) years who were consulted at the Department of Pediatric Psychosomatic Medicine at Okayama University Hospital from 2013 to 2018 and underwent the P-F study. Each score was compared with a standardization sample. The mean group conformity rating did not differ significantly between the participants and healthy children. Compared with healthy children, those with psychosomatic diseases were less likely to explain their perspective. The children with psychosomatic disorders responded to frustrating situations in a sensible and age-appropriate manner. However, they were less likely to respond by explaining their perspective to protect themselves.
Keywords psychosomatic disorder picture-frustration study children projective technique group conformity rating
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 185
End Page 192
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094956
Web of Science KeyUT 000982503800008
JaLCDOI 10.18926/AMO/65147
FullText URL 77_2_179.pdf
Author Kondo, Hidenori| Saito, Taichi| Nakahara, Ryuichi| Nakamichi, Ryo| Shimamura, Yasunori| Harada, Ryozo| Imatani, Junya| Ozaki, Toshifumi|
Abstract Rupture of the extensor pollicis longus (EPL) tendon is a known complication after undisplaced distal radius fracture (DRF). However, no report has revealed the relationship between EPL tendon rupture and the fracture pattern. Thus, this study aimed to investigate the characteristics of fractures at risk of EPL tendon rupture using fracture line mapping of undisplaced DRFs. This study used computed tomography imaging data of undisplaced DRFs with (n=18) and without EPL tendon rupture (n=52). Fracture lines obtained from 3D reconstruction data were drawn manually after matching with a 2D template wrist model. Fracture maps represented the fracture line distribution by superimposing the fracture lines of all 70 patients. Heat maps showed the relative frequency of the fracture lines as a gradual color change. Fracture lines of cases with EPL tendon rupture were concentrated in the proximal border of Lister’s tubercle. By contrast, fracture lines of cases without EPL tendon rupture were relatively dispersed.
Keywords distal radius fracture rupture of extensor pollicis longus tendon fracture mapping
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 179
End Page 184
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094955
Web of Science KeyUT 000982503800007
JaLCDOI 10.18926/AMO/65146
FullText URL 77_2_169.pdf
Author Inoue, Kanae| Fujita, Rio| Nagahara, Takatoshi| Murakami, Shiho| Nagai, Yuta| Moriwake, Rina| Miyake, Nozomi| Wakuta, Akiko| Kariyama, Kazuya| Nishimura, Mamoru| Nouso, Kazuhiro|
Abstract Alcoholic liver disease is a risk factor for non-virus-related hepatocellular carcinoma (HCC), which is increasing in prevalence. This study aimed to identify the factors for recovery from alcoholic liver failure. Sixty-two consecutive patients hospitalized for alcoholic liver failure at Okayama City Hospital were enrolled. The characteristics of patients who survived to the 1-month follow-up and whose liver function improved to Child–Pugh A at 3 months (CPA3) and 12 months (CPA12) were compared with the rest of the patients. The survivors at 1 month (50 patients) were significantly younger than the deceased patients and had better liver and renal function with higher levels of γ-glutamyl transferase (GGT). The same factors, except renal function, were correlated with achieving CPA3. High AST, ALT, and GGT levels as well as short spleen length, total abstinence, and good Child–Pugh scores at admission were identified as factors for achieving CPA12. The extent of alcohol intake before admission was not identified as a risk factor in any analysis. In conclusion, baseline liver function is crucial for survival and achieving CPA3, whereas high transaminase and γ-GTP levels, the absence of splenomegaly, and total abstinence are significant factors for achieving CPA12.
Keywords alcoholic liver failure risk factors recovery
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 169
End Page 177
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094954
Web of Science KeyUT 000982503800006
JaLCDOI 10.18926/AMO/65145
FullText URL 77_2_161.pdf
Author Yamanoi, Tomoko| Suzuki, Satoshi| Kaku, Ryuji| Morimatsu, Hiroshi|
Abstract An intraoperative double-low condition is defined as concurrent low values for bispectral index (BIS) and mean arterial pressure (MAP), and may predict perioperative outcomes. We hypothesized that prolonged double-low times might be associated with an increased incidence of postoperative delirium. We conducted a single-center retrospective observational study on patients who had been admitted to our hospital’s intensive care unit (ICU) after surgery and whose BIS and MAP data had been recorded during general anesthesia. The primary outcome was the incidence of postoperative delirium. A double-low condition was defined as BIS < 45 and MAP <75 mmHg. The total double-low time was calculated in 1-min increments and used to divide the patients into quintiles. Multiple logistic regression analyses were conducted. Among the 334 patients included in the study, the incidence of postoperative delirium was 15.6% (n=52). Multiple logistic regression analysis revealed that a prolonged double-low time, defined as a total double-low time of > 42 min (i.e., third, fourth, and fifth quintiles), was significantly associated with an increased incidence of postoperative delirium (adjusted odds ratio: 2.61, 95% confidence interval: 1.27-5.37, p=0.009). Prolonged double-low time during general anesthesia was independently associated with an increased incidence of postoperative delirium in surgical ICU patients.
Keywords postoperative delirium bispectral index hypotension double-low condition general anesthesia
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 161
End Page 167
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094953
Web of Science KeyUT 000982503800005
JaLCDOI 10.18926/AMO/65144
FullText URL 77_2_147.pdf
Author Arias, Zulema| Haines, Stephanie| Yamamoto, Tadashi| Hatanaka, Kazu| Yamashiro, Keisuke| Sonoi, Norihiro| Takashiba, Shogo|
Abstract The curriculum at the Department of Pathophysiology in the Periodontal Sciences program at Okayama University includes normative preclinical training (NPT) using phantoms. NPT is given to the whole class of 5 th year students divided in groups of 8 students/instructor. In 2019, an innovative personalized preclinical training (PPT) pilot study was implemented for this group of students whereby two students, each with their own dental unit, were coached by one instructor. The main topics covered were dental ergonomics and endodontics. We aimed to evaluate the effectiveness of PPT in dental ergonomics and endodontics toward increasing the knowledge and future clinical skills of students who had already undergone NPT. A test on endodontics was taken before and after PPT. A questionnaire was completed to assess their perception of improvement regarding the above-mentioned topics. Test scores and questionnaire results both showed that the students’ level of knowledge and awareness of future clinical skills was significantly higher after PPT. This pilot study demonstrated that PPT increased the students’ knowledge and future clinical skills. As preclinical training forms the foundation for clinical practice, investment in future research regarding this personalized approach is likely to enhance students’ understanding and clinical performance.
Keywords preclinical personalized education dental ergonomics endodontics clinical skills improvement undergraduate students
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 147
End Page 159
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094952
Web of Science KeyUT 000982503800004
JaLCDOI 10.18926/AMO/65143
FullText URL 77_2_139.pdf
Author Namio, Keiichi| Kondo, Takashi| Miyatake, Nobuyuki| Hishii, Shuhei| Nishi, Hiroyuki| Katayama, Akihiko| Ujike, Kazuhiro| Suzuki, Hiromi| Koumoto, Kiichi|
Abstract We investigated the link between prolonged sedentary bouts and all-cause mortality in patients on chronic hemodialysis, using a prospective cohort. A total of 104 outpatients on chronic hemodialysis from 2013 to 2019, aged 71.4±11.4 years, were enrolled. Prolonged sedentary bouts (≥ 30 min and ≥60 min) (min and bouts) and relative prolonged sedentary bouts (≥ 30 min and ≥ 60 min) (%) on the patients’ non-hemodialysis days were measured by a tri-accelerometer, and we also analyzed the patients’ clinical parameters. The relationship between prolonged sedentary bouts and all-cause mortality was evaluated by a survival analysis and the Cox proportional hazard model. Thirty-five patients died during the follow-up period. A Kaplan-Meier analysis detected significant differences in the survival rate between two groups stratified by the median for all prolonged sedentary-bout parameters. After the adjustment for confounding factors, all of the prolonged sedentary-bout parameters were determinant factors for all-cause mortality. These results indicate that prolonged sedentary bouts on non-hemodialysis days were closely related to all-cause mortality in the patients on hemodialysis.
Keywords sedentary bout mortality hemodialysis survival analysis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 139
End Page 145
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094951
Web of Science KeyUT 000982503800003
JaLCDOI 10.18926/AMO/65142
FullText URL 77_2_131.pdf
Author Senda, Mayuko| Terada, Seishi| Fujiwara, Masaki| Yamada, Norihito|
Abstract Eating disorders (EDs) are associated with a high mortality rate. Patients with EDs often experience severe dehydration due to food restriction and/or vomiting. Severely underweight patients are often prescribed bed rest during inpatient care to reduce their energy consumption, and they may thus develop multiple risk factors for venous thromboembolism (VTE). We compared the clinical features of ED inpatients with VTE to those of ED inpatients without VTE. Seventy-one inpatients with ED were treated at Okayama University Hospital’s psychiatric ward in 2016-2020; five were experienced a VTE. Compared to the non-VTE group, the VTE group’s median age and disease duration were greater and the median body mass index (BMI) was lower. The VTE group’s D-dimer peak values were > 5 mg/L. Physical restraint and central venous catheter use were associated with VTE. Longer ED duration and lower BMI might be risk factors for VTE. To make inpatient treatment for ED safer, it is important to avoid the use of physical restraints and central venous catheters. Continuous D-dimer monitoring is necessary for the early detection of VTE in ED patients at high risk of VTE.
Keywords eating disorder anorexia nervosa venous thromboembolism deep vein thrombosis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-04
Volume volume77
Issue issue2
Publisher Okayama University Medical School
Start Page 131
End Page 137
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37094950
Web of Science KeyUT 000982503800002