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Author Takeuchi, Noriko| Sawada, Nanami| Inada, Sakura| Morita, Manabu| Ekuni, Daisuke|
Published Date 2026-01-09
Publication Title Communications Medicine
Volume volume6
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 96
ISSN 2730-664X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026
File Version publisher
PubMed ID 41513837
DOI 10.1038/s43856-025-01361-0
Web of Science KeyUT 001686043700001
Related Url isVersionOf https://doi.org/10.1038/s43856-025-01361-0
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Author Fujii, Yasushi| Nakayama, Takahiro| Oshita, Junki| Tsunoda, Ayaka| Saeki, Yusuke| Tanabe, Yoshinori|
Keywords flex map sagging Winston–Lutz test
Published Date 2026
Publication Title Journal of Radiotherapy in Practice
Volume volume25
Publisher Cambridge University Press (CUP)
Start Page e5
ISSN 1460-3969
NCID AA11974173
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s), 2026.
File Version publisher
DOI 10.1017/s1460396926100387
Related Url isVersionOf https://doi.org/10.1017/s1460396926100387
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Author Hagiya, Hideharu| Nishimura, Yoshito| Harada, Ko| Yamamoto, Maki| Takeda, Tatsuaki| Vu, Quynh Thi| Belangoy, Keith Pardillada| Ouddoud, Hanane| Zamami, Yoshito| Koyama, Toshihiro|
Keywords Aging Locally weighted regression model Infection Clostridioides difficile Disparity
Published Date 2026-03
Publication Title International Journal of Infectious Diseases
Volume volume164
Publisher Elsevier BV
Start Page 108315
ISSN 1201-9712
NCID AA11238338
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 41456768
DOI 10.1016/j.ijid.2025.108315
Web of Science KeyUT 001678827200001
Related Url isVersionOf https://doi.org/10.1016/j.ijid.2025.108315
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Author Takeuchi, Junko S| Matsunaga, Nobuaki| Tsukada, Ai| Iwamoto, Noriko| Fuwa, Noriko| Ichikawa, Takahiro| Kato, Yasuyuki| Tomita, Yuka| Kitagawa, Hiroki| Yamato, Masaya| Aoyagi, Tetsuji| Hagiya, Hideharu| Hase, Ryota| Hatakeyama, Shuji| Inaba, Tohru| Izumikawa, Koichi| Takesue, Yoshio| Kimura, Moto| Ohmagari, Norio|
Keywords influenza a nasal vestibular swab nasopharyngeal swab rapid diagnostics rt-qpcr saliva sari
Published Date 2026-01-05
Publication Title Cureus
Volume volume18
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page e100872
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2026 Takeuchi et al.
File Version publisher
PubMed ID 41658625
DOI 10.7759/cureus.100872
Related Url isVersionOf https://doi.org/10.7759/cureus.100872
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Author Nishio, Ayano| Iwamuro, Masaya| Inokuchi, Toshihiro| Ishiguro, Mikako| Aoyama, Yuki| Takahara, Masahiro| Hiraoka, Sakiko| Oguni, Kohei| Hagiya, Hideharu| Matsuoka, Yuto| Kanazawa, Tomoyuki| Otsuka, Motoyuki|
Keywords crohn’s disease (cd) group a streptococcus immunosuppression intestinal obstruction streptococcal toxic shock syndrome (stss)
Published Date 2025-12-26
Publication Title Cureus
Volume volume17
Issue issue12
Publisher Springer Science and Business Media LLC
Start Page e100138
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2025 Nishio et al.
File Version publisher
PubMed ID 41589146
DOI 10.7759/cureus.100138
Related Url isVersionOf https://doi.org/10.7759/cureus.100138
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Author Hayashi, Tatsuya| Okazaki, Mikio| Mitsuhashi, Toshiharu| Yamamoto, Hidetaka| Habu, Tomohiro| Shien, Kazuhiko| Suzawa, Ken| Yamamoto, Hiromasa| Otsuka, Tomoaki| Watanabe, Mototsugu| Kurosaki, Takeshi| Yamada, Eiji| Matsuda, Eisuke| Hayashi, Tatsurou| Fujiwara, Toshiya| Hayama, Makio| Tao, Hiroyuki| Yamane, Masaomi| Inokawa, Hidetoshi| Hirami, Yuji| Washio, Kazuhiro| Misao, Takahiko| Yamashita, Motohiro| Sano, Yoshifumi| Nakata, Masao| Kawamata, Osamu| Toyooka, Shinichi|
Keywords partial thymectomy real-world data analysis retrospective comparative cohort study thymic carcinoma thymic epithelial tumors total thymectomy
Published Date 2025-10-10
Publication Title International Journal of Surgery
Volume volume112
Issue issue2
Publisher Ovid Technologies (Wolters Kluwer Health)
Start Page 2301
End Page 2310
ISSN 1743-9159
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.
File Version publisher
PubMed ID 41085661
DOI 10.1097/js9.0000000000003600
Related Url isVersionOf https://doi.org/10.1097/js9.0000000000003600
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Author Imano, Natsumi| Nishida, Mikako| Tokumasu, Miho| Zhao, Weiyang| Yamashita, Nahoko| Udono, Heiichiro|
Keywords ascochlorin derivative CD8 positive T lymphocytes cell survival IFN-γ interleukin-9 Tc9 tumour immunity
Published Date 2026-02-19
Publication Title British Journal of Pharmacology
Publisher Wiley
ISSN 0007-1188
NCID AA00574810
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 41715914
DOI 10.1111/bph.70316
Related Url isVersionOf https://doi.org/10.1111/bph.70316
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Author Matsuoka, Daiki| Suehara, Kana| Naka, Shuhei| Misaki, Taro| Nagasawa, Yasuyuki| Ito, Seigo| Suehiro, Yuto| Nomura, Ryota| Nakano, Kazuhiko| Matsumoto-Nakano, Michiyo|
Keywords bacterial surface proteins collagen-binding protein human immunoglobulins IgA nephropathy Streptococcus mutans
Published Date 2026-01-07
Publication Title Frontiers in Cellular and Infection Microbiology
Volume volume15
Publisher Frontiers Media SA
Start Page 1673581
ISSN 2235-2988
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 Matsuoka, Suehara, Naka, Misaki, Nagasawa, Ito, Suehiro, Nomura, Nakano and Matsumoto-Nakano.
File Version publisher
PubMed ID 41574301
DOI 10.3389/fcimb.2025.1673581
Web of Science KeyUT 001665990400001
Related Url isVersionOf https://doi.org/10.3389/fcimb.2025.1673581
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Author Kong, Dezheng| Funabiki, Nobuo| Kyaw, Htoo Htoo Sandi| Kotama, I Nyoman Darma| Zhu, Zihao| Rahmadani, Alfiandi Aulia|
Keywords internet of things AI retrieval-augmented generation vector database schema-based extraction data sheet technical information
Published Date 2026-02-07
Publication Title Sensors
Volume volume26
Issue issue4
Publisher MDPI AG
Start Page 1081
ISSN 1424-8220
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
DOI 10.3390/s26041081
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Author Haz, Amma Liesvarastranta| Brata, Komang Candra| Funabiki, Nobuo| Kyaw, Htoo Htoo Sandi| Fajrianti, Evianita Dewi| Sukaridhoto, Sritrusta|
Keywords slide annotation multimodal analysis speech-to-text LLM SUS
Published Date 2026-02-01
Publication Title Algorithms
Volume volume19
Issue issue2
Publisher MDPI AG
Start Page 110
ISSN 1999-4893
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
DOI 10.3390/a19020110
Related Url isVersionOf https://doi.org/10.3390/a19020110
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Author Wardani, Ni Wayan| Funabiki, Nobuo| Kyaw, Htoo Htoo Sandi| Zhu, Zihao| Kotama, I Nyoman Darma| Sugiartawan, Putu| Putra, I Nyoman Agus Suarya|
Keywords database programming SQL query description problem (SDP) self-study programming learning assistant system (PLAS) generative AI
Published Date 2026-01-09
Publication Title Information
Volume volume17
Issue issue1
Publisher MDPI AG
Start Page 65
ISSN 2078-2489
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
DOI 10.3390/info17010065
Web of Science KeyUT 001670537100001
Related Url isVersionOf https://doi.org/10.3390/info17010065
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Author Permatasari, Perwira Annissa Dyah| Mentari, Mustika| Kinari, Safira Adine| Aung, Soe Thandar| Funabiki, Nobuo| Kyaw, Htoo Htoo Sandi| Wai, Khaing Hsu|
Keywords Java programming learning JPLAS JUnit code writing problem plagiarism Levenshtein distance threshold IQR AI-generated
Published Date 2025-12-26
Publication Title Analytics
Volume volume5
Issue issue1
Publisher MDPI AG
Start Page 2
ISSN 2813-2203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 by the authors.
File Version publisher
DOI 10.3390/analytics5010002
Related Url isVersionOf https://doi.org/10.3390/analytics5010002
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Author Zhu, Zihao| Funabiki, Nobuo| Sandi Kyaw, Htoo Htoo| Kotama, I Nyoman Darma| Pradhana, Anak Agung Surya| Rahmadani, Alfiandi Aulia| Noprianto|
Keywords IoT MQTT protocol AI-assisted learning exercise-based education Python programming docker learning platform
Published Date 2025-12-18
Publication Title Electronics
Volume volume14
Issue issue24
Publisher MDPI AG
Start Page 4967
ISSN 2079-9292
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 by the authors.
File Version publisher
DOI 10.3390/electronics14244967
Web of Science KeyUT 001646413000001
Related Url isVersionOf https://doi.org/10.3390/electronics14244967
JaLCDOI 10.18926/AMO/70075
FullText URL 80_1_069.pdf
Author Wakatsuki, Shinya| Sakamoto, Shinya| Ueno, Akiko| Namba, Takaomi| Yamamoto, Yorito| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro|
Abstract Patients with hepatocellular carcinoma (HCC) and extensive peritoneal dissemination generally have a poor prognosis and are often resistant to systemic therapy. We report the case of a 47-year-old woman with HCC and massive peritoneal dissemination who presented with malignant ascites requiring repeated cell-free and concentrated ascites reinfusion therapy and peritoneovenous shunt placement, as well as malignant pleural effusion requiring pleurodesis. Combined immunotherapy with durvalumab/tremelimumab was initiated;however, disease progression was observed after three treatment courses, prompting a switch to lenvatinib therapy. Two months after initiation of lenvatinib, CT imaging demonstrated complete disappearance of arterial enhancement in the primary hepatic lesion, along with reduction in the size of peritoneal dissemination nodules. Thirteen months after switching to lenvatinib (16 months after the initial diagnosis), the alpha-fetoprotein level continued to decrease, and the disease remained stable under treatment. Despite the extremely high tumor burden, lenvatinib achieved disease stabilization and symptomatic improvement.
Keywords diagnostic laparoscopy hepatocellular carcinoma peritoneal dissemination lenvatinib
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 69
End Page 74
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748152
Web of Science KeyUT 001712986800001
JaLCDOI 10.18926/AMO/70074
FullText URL 80_1_063.pdf
Author Takasu, Eri| Shiode, Yusuke| Kindo, Hiroya| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Kanzaki, Yuki| Morita, Tetsuro| Adachi, Takuya| Otsuka, Motoyuki| Morizane, Yuki|
Abstract A 77-year-old man undergoing treatment for hepatocellular carcinoma (HCC) presented with blurred vision in his right eye, persisting for 2 months. Slit-lamp microscopy and fundus examination revealed inflammatory cells in the anterior chamber, severe vitreous opacities, and retinal vasculitis in the right eye. The patient underwent vitreous surgery with biopsy, and vitreous cytology confirmed a metastatic intraocular tumor originating from the HCC. Radiotherapy was administered to the right eye, with no recurrence of intraocular inflammation observed at 10 months post-irradiation.
Keywords metastatic intraocular tumor hepatocellular carcinoma panuveitis uveitis masquerade syndrome
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 63
End Page 67
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748151
Web of Science KeyUT 001712997700001
JaLCDOI 10.18926/AMO/70073
FullText URL 80_1_055.pdf
Author Akazawa, Hidemasa| Hagiya, Hideharu| Fukushima, Shinnosuke| Yamamoto, Shohei| Nakano, Yasuhiro| Otsuka, Fumio|
Abstract In Japan, antiviral agents for COVID-19 were freely available until September 2023 as part of national policy. This study evaluated changes in these agents’ prescribing patterns and the patient outcomes following the policy shift. We conducted a multicenter retrospective study at four hospitals in Japan’s Okayama and Kagawa prefectures from January 2022 to March 2024. The study period was divided into the public-expenditure phase (January 2022 to September 2023) and the post-expenditure phase (October 2023 to March 2024). We extracted the hospitalized patients’ clinical data from the electronic database. The study’s primary outcome was the antiviral prescription rate; the secondary outcome was in-hospital mortality. Among the 302 hospitalized patients (median age 85 years), 52.0% were classified as having a mild condition. Of the patients with mild conditions, 37.7% were diagnosed in outpatient settings prior to hospitalization. During the public-expenditure phase, 47.4% of the patients received antivirals as outpatients, mainly molnupiravir (80.9%). In the post-expenditure period, 80.0% of the patients were prescribed antivirals, mostly molnupiravir (91.7%). The antiviral prescription rate was significantly higher after the policy change. The overall in-hospital mortality was 15.8%, with no significant difference between the two periods (17.0% vs. 10.5%). Despite the termination of government funding, antiviral prescriptions remained frequent at community hospitals located in highly aging regions of western Japan such as Okayama and Kagawa prefectures. Mortality remains high among the elderly, highlighting the need for continued antiviral therapy and booster vaccinations.
Keywords coronavirus disease 2019 public expenditure prescribing pattern prognosis Japan
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 55
End Page 62
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748150
Web of Science KeyUT 001712994500007
JaLCDOI 10.18926/AMO/70072
FullText URL 80_1_047.pdf
Author Eguchi, Yukiomi| Ushio, Soichiro| Irie, Keiichi| Yamashita, Yuta| Eguchi, Miyu| Nakano, Takafumi| Mishima, Kenichi|
Abstract Deregulation of cannabis use is gradually expanding in Europe and the United States. However, the biological processes driving tolerance to delta-9-tetrahydrocannabinol (Δ9-THC), the main psychoactive component of cannabis, remain unclear. Thus, this study aimed to investigate the mechanisms and time course of tolerance development and loss to Δ9-THC in mice. Male ICR mice (7 weeks old) were administered Δ9-THC once daily for 3 days and then divided into three groups according to the washout period (3-, 10-, and 17-day washout groups). After each washout, changes in body temperature and locomotor activity were measured following re-exposure to Δ9-THC. Furthermore, the mRNA expression levels of CB1 and CB2 receptors in the brain were evaluated using real-time PCR. On day 1, significant hypothermia and reduced spontaneous locomotor activity were observed in the Δ9-THC-treated mice compared with the vehicle-treated mice. Tolerance to the hypothermic and locomotor-suppressing effects of Δ9-THC developed on days 2 and 3, respectively, and dissipated after 3 and 11 days of washout, respectively. These differences in the rates of tolerance development and recovery may reflect distinct underlying mechanisms. No significant changes in receptor mRNA expression were observed. These findings highlight the complexity of Δ9-THC tolerance and its potential implications for long-term cannabis use.
Keywords delta-9-tetrahydrocannabinol cannabis tolerance locomotor hypothermic
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 47
End Page 54
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748149
Web of Science KeyUT 001712994500006
JaLCDOI 10.18926/AMO/70071
FullText URL 80_1_039.pdf
Author Tezel, Nihal| Can, Aslı Gençay|
Abstract The study aimed to determine the prevalence of kinesiophobia in patients who had undergone lumbar microdiscectomy and to examine its associations with pain intensity, disability, quality of life, depression, anxiety, and satisfaction with surgery. Forty-eight patients with microdiscectomy and 48 healthy controls were enrolled. The Tampa Scale for Kinesiophobia (TSK), Roland-Morris Disability Index (RMDI), Hospital Anxiety and Depression Scale (HADS-A and HADS-D, respectively), and Short Form-36 Health Survey (SF-36) were administered to both groups. The scores of TSK, RMDI, HADS-A, and HADS-D were significantly higher and SF-36 scores were significantly lower in the microdiscectomy than the control group (p<0.001 for all). In the microdiscectomy group, median (min-max) RMDI, HADS-A, and HADS-D scores were 19 (4-34), 10 (0-18), and 9 (0-18), respectively, in kinesiophobic patients, and were significantly higher than 6 (2-20), 3 (0-11), 2.5 (0-11) in non-kinesiophobic patients (all p<0.001). The median (min-max) SF-36 PCS, SF-36 MCS, and VAS scores for surgery satisfaction were 36.5 (8.7-75), 52.1 (11-95), 5, 5 (0-10), respectively, in kinesiophobic patients and were significantly lower than 71 (28-95), 85.5 (9-93), 8.5 (3-10) in non-kinesiophobic patients (all p<0.05). TSK scores were significantly correlated with RMDI, HADS-A, HADS-D, SF-36, and surgery satisfaction scores (all p<0.05). Kinesiophobic patients with lumbar microdiscectomy therefore showed greater disability and psychological morbidity, poorer quality of life, and lower satisfaction with surgery.
Keywords kinesiophobia microdiscectomy disability quality of life depression
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 39
End Page 46
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748148
Web of Science KeyUT 001712994500005
JaLCDOI 10.18926/AMO/70070
FullText URL 80_1_031.pdf
Author Ishibashi, Kyota| Oishi, Hirotaka| Araki, Ryo| Kawamura, Kosuke| Sasaki, Isamu| Sasaki, Eiji| Kamada, Hikaru| Kogawa, Masakazu| Tanaka, Sunao| Numasawa, Takuya| Ishibashi, Yasuyuki|
Abstract We investigated global alignment changes following total hip arthroplasty (THA) and predictive alignment parameters for increased cup anteversion (CA) by retrospectively analyzing the primary THA data of 75 patients treated at our hospital (49 women, 26 men; age 65.1±5.7 years, BMI 28.3±3.4 kg/m2). Global alignment parameters, i.e., the anterior pelvic plane angle (APPa) and proximal femoral shaft angle (PFSa) and other alignment parameters were measured. CA was evaluated based on the patients’ standing coronal radiographs. ΔCA was defined as the difference in CA from 2 weeks before to 1 year after each THA. We classified the cases as stable (S) (CA < 10°; n=63) and pelvic retroversion (R) (CA ≥ 10°; n=12) groups. Associations between ΔCA and alignment parameters were evaluated by linear regression and a receiver operating characteristic (ROC) analysis. A significant decrease in the PFSa occurred between the 2-week and 1-year post-THA timepoints (7.8±4.3° vs. 4.2±3.6°, p<0.001), with no notable change in other alignment parameters. At 1-year post-THA, the CA of 12 (16%) patients had increased to 4.5±4.4°. Only the preoperative APPa was positively associated with ΔCA (β=0.165, p=0.020). The ROC analysis revealed that the optimal cut-off value for increased CA in the APPa is 2.1° (area under the curve, 0.700; p=0.020; odds ratio, 4.80). The APPa change predicted increased CA, which emphasizes the importance of the use of preoperative standing radiography for identifying the optimal cup positioning for post-THA changes in CA.
Keywords total hip arthroplasty global alignment anterior pelvic plane cup anteversion pelvic tilt
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 31
End Page 37
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748147
Web of Science KeyUT 001712994500004
JaLCDOI 10.18926/AMO/70069
FullText URL 80_1_017.pdf
Author Yano, Hideki| Takahata, Yoko| Yamaguchi, Takeshi| Saito, Shinya|
Abstract This study aimed to develop a scale enabling nurses to objectively evaluate their own stroke discharge support, as a basis for enhancing its overall effectiveness. A draft scale was created based on a literature review, and consisted of a 51-item, 5-point Likert-type questionnaire administered to ward nurses engaged in stroke discharge support at acute care hospitals. Factor analysis was performed to refine the scale. Construct validity was assessed using the known-groups method, and reliability was evaluated through internal consistency analysis. The resulting Stroke Discharge Support Evaluation Scale comprises 29 items across 5 factors, each rated on a 5-point Likert scale. Analysis of the data collected from 237 valid responses demonstrated good internal consistency and supported the scale’s construct validity. The Stroke Discharge Support Evaluation Scale is a reliable and valid tool enabling ward nurses in acute care hospitals to evaluate their own stroke discharge support.
Keywords stroke discharge support scale development
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 17
End Page 30
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748146
Web of Science KeyUT 001712994500003