result 1271 件
FullText URL | fulltext.pdf |
---|---|
Author | Maruo, Yukinori| Yoshihara, Kumiko| Irie, Masao| Nagaoka, Noriyuki| Matsumoto, Takuya| Minagi, Shogo| |
Keywords | acrylate methacrylate CAD/CAM flexural strength shear bond strength |
Published Date | 2022-10-28 |
Publication Title | Materials |
Volume | volume15 |
Issue | issue21 |
Publisher | MDPI |
Start Page | 7564 |
ISSN | 1996-1944 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 by the authors. |
File Version | publisher |
PubMed ID | 36363156 |
DOI | 10.3390/ma15217564 |
Web of Science KeyUT | 000881219600001 |
Related Url | isVersionOf https://doi.org/10.3390/ma15217564 |
FullText URL | fulltext.pdf |
---|---|
Author | Tsuge, Mitsuru| Kodera, Aya| Sumitomo, Hiromi| Araki, Tooru| Yoshida, Ryuichi| Yasui, Kazuya| Sato, Hiroki| Washio, Yosuke| Washio, Kana| Shigehara, Kenji| Yashiro, Masato| Yagi, Takahito| Tsukahara, Hirokazu| |
Keywords | Neonatal hemochromatosis Thalassemia Liver transplantation Gestational alloimmune liver disease Case report Hepcidin Ineffective erythropoiesis Growth differentiation factor-15 |
Published Date | 2022-10-29 |
Publication Title | BMC Pediatrics |
Volume | volume22 |
Issue | issue1 |
Publisher | BMC |
Start Page | 622 |
ISSN | 1471-2431 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2022. |
File Version | publisher |
PubMed ID | 36309641 |
DOI | 10.1186/s12887-022-03706-3 |
Web of Science KeyUT | 000876287400002 |
Related Url | isVersionOf https://doi.org/10.1186/s12887-022-03706-3 |
JaLCDOI | 10.18926/AMO/64122 |
---|---|
FullText URL | 76_6_715.pdf |
Author | Mohammed Zahedul Islam Nizami| Gorduysus, Melahat| Shinoda-Ito, Yuki| Yamamoto, Tadashi| Nishina, Yuta| Takashiba, Shogo| Arias, Zulema| |
Abstract | The failure of endodontic treatment is directly associated with microbial infection in the root canal or periapical areas. An endodontic sealer that is both bactericidal and biocompatible is essential for the success of root canal treatments. This is one of the vital issues yet to be solved in clinical dental practice. This in vitro study assessed the effectiveness of graphene oxide (GO) composites GO-CaF2 and GO-Ag-CaF2 as endodontic sealer materials. Dentin slices were coated with either the GO-based composites or commonly used root canal sealers (non-eugenol zinc oxide sealer). The coated slices were treated in 0.9% NaCl, phosphate-buffered saline (PBS), and simulated body fluid (SBF) at 37˚C for 24 hours to compare their sealing effect on the dentin surface. In addition, the radiopacity of these composites was examined to assess whether they complied with the requirements of a sealer for good radiographic visualization. Scanning electron microscopy showed the significant sealing capability of the composites as coating materials. Radiographic images confirmed their radiopacity. Mineral deposition indicated their bioactivity, especially of GO-Ag-CaF2, and thus it is potential for regenerative application. They were both previously shown to be bactericidal to oral microbes and cytocompatible with host cells. With such a unique assemblage of critical properties, these GO-based composites show promise as endodontic sealers for protection against reinfection in root canal treatment and enhanced success in endodontic treatment overall. |
Keywords | bioactive sealer graphene oxide mineral deposition antimicrobial activity radiopacity |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2022-12 |
Volume | volume76 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 715 |
End Page | 721 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 36549774 |
Web of Science KeyUT | 000905195100012 |
JaLCDOI | 10.18926/AMO/64120 |
---|---|
FullText URL | 76_6_695.pdf |
Author | Onishi, Hideki| Nouso, Kazuhiro| Takaki, Akinobu| Oyama, Atsushi| Adachi, Takuya| Wada, Nozomu| Takeuchi, Yasuto| Shiraha, Hidenori| Okada, Hiroyuki| |
Abstract | This study sought to identify factors that are predictive of a therapeutic response to hepatic arterial infusion chemotherapy (HAIC) by focusing on the number of prior transcatheter arterial chemoembolization (TACE) sessions. To determine the parameters predicting a good response to HAIC, we retrospectively analyzed 170 patients with hepatocellular carcinoma (HCC) who received HAIC regimens comprising low-dose cisplatin combined with 5-fluorouracil (LFP) or cisplatin (CDDP) for the first time. In both the LFP and CDDP regimens, the response rates were significantly lower in patients with three or more prior TACE sessions than in those with two or fewer prior TACE sessions (LFP 57% versus 28%; p=0.01, CDDP 27% versus 6%; p=0.01). Multivariable logistic regression analysis revealed that the number of prior TACE sessions (≥ 3) was significantly associated with non-responder status (odds ratio 4.17, 95% Confidence Interval (CI) 1.76-9.86) in addition to the HAIC regimen. Multivariable analysis using the Cox proportional hazards model revealed that a larger number of prior TACE sessions (≥ 3) was a significant risk factor for survival (hazard ratio 1.60, 95% CI 1.12-2.29) in addition to Child-Pugh class, serum alpha-fetoprotein concentration, and maximum diameter of HCC. HCC patients who receive fewer prior TACE sessions (≤ 2) were found to be better responders to HAIC. |
Keywords | hepatic arterial infusion chemotherapy hepatocellular carcinoma refractory transcatheter arterial chemoembolization |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2022-12 |
Volume | volume76 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 695 |
End Page | 703 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 36549772 |
Web of Science KeyUT | 000905195100010 |
JaLCDOI | 10.18926/AMO/64117 |
---|---|
FullText URL | 76_6_673.pdf |
Author | Okazawa-Sakai, Mika| Yamamoto, Yasuko| Futagawa, Mashu| Okamura, Miki| Miyawaki, Satoko| Nishina, Tomohiro| Takehara, Kazuhiro| Kozuki, Toshiyuki| Tomida, Shuta| Hyodo, Ichinosuke| Ohsumi, Shozo| Hirasawa, Akira| |
Abstract | Patients found to have presumed germline pathogenic variants (PGPVs) during comprehensive genomic profiling (CGP) require genetic counseling (GC) referrals. We retrospectively investigated the outcomes of patients with PGPVs. Among 159 patients who underwent CGP, we recommended GC for the 16 patients with PGPVs (3 with [FG group] and 13 without [G Group] a family/personal history of hereditary cancer) as well as for the 8 patients with no PGPVs, but a history (F group); 2 (67%), 5 (38%), and 3 (38%) patients received GC in the FG, G, and F groups, respectively. Germline testing results were positive in 1 and 2 patients of the FG and G groups, respectively. Among the patients recommended for GC, 58% did not receive GC due to lack of interest, poor performance status, or death. CGP contributes to the identification of germline variants in patients without a history of hereditary cancer. However, the proportion of patients who undergo GC should be improved. |
Keywords | comprehensive genomic profiling hereditary cancer germline findings presumed germline pathogenic variant(s) genetic counseling |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2022-12 |
Volume | volume76 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 673 |
End Page | 678 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 36549769 |
Web of Science KeyUT | 000905195100007 |
FullText URL | K0006716_abstract_review.pdf K0006716_fulltext.pdf |
---|---|
Author | TAKIGAHIRA, Yoshiaki| |
Published Date | 2022-09-22 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第6716号 |
Granted Date | 2022-09-22 |
Thesis Type | Doctor of Philosophy in Engineering |
Grantor | 岡山大学 |
language | Japanese |
JaLCDOI | 10.18926/AMO/64044 |
---|---|
FullText URL | 76_5_609.pdf |
Author | Matsumoto, Ken| Fujishita, Keigo| Matsuda, Masayuki| Oka, Satoshi| Fujisawa, Yuka| Imai, Toshi| Machida, Takuya| |
Abstract | A 69-year-old Japanese man with acute leukemia received post-transplant cyclophosphamide-based haploidentical stem cell transplantation (PTCY-haplo-SCT) but was readmitted with dyspnea and ground-glass-opacities of the lungs. Bronchoscopy showed inflammatory changes with no signs of infection. He received steroids but required intubation as his condition deteriorated. In addition to antithymocyte globulin and cyclophosphamide, we administered ruxolitinib but failed to save him. Autopsy findings revealed fibrotic nonspecific interstitial pneumonia (NSIP) without evidence of organizing pneumonia or infection. Thus, we diagnosed idiopathic pneumonia syndrome (IPS). As far as our knowledge, this is the first case of IPS with NSIP histology after PTCY-haplo-SCT. |
Keywords | idiopathic pneumonia syndrome ruxolitinib post-transplant cyclophosphamide-based haploidentical stem cell transplantation nonspecific interstitial pneumonia |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2022-10 |
Volume | volume76 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 609 |
End Page | 615 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 36352810 |
Web of Science KeyUT | 000884907100016 |
FullText URL | fulltext.pdf |
---|---|
Author | Esumi, Satoru| Ushio, Soichiro| Zamami, Yoshito| |
Keywords | Alzheimer's disease polypharmacy drug interactions |
Published Date | 2022-10-13 |
Publication Title | Medicina-Lithuania |
Volume | volume58 |
Issue | issue10 |
Publisher | MDPI |
Start Page | 1445 |
ISSN | 1010-660X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 by the authors. |
File Version | publisher |
PubMed ID | 36295605 |
DOI | 10.3390/medicina58101445 |
Web of Science KeyUT | 000875259600001 |
Related Url | isVersionOf https://doi.org/10.3390/medicina58101445 |
JaLCDOI | 10.18926/AMO/64024 |
---|---|
FullText URL | 76_5_489.pdf |
Author | Matsumoto, Yuji| Ichikawa, Tomotsugu| Kurozumi, Kazuhiko| Date, Isao| |
Abstract | Glioblastoma (GBM) is a fatal primary malignant brain tumor in adults. Despite decades of research, the prognosis for GBM patients is still disappointing. One major reason for the intense therapeutic resistance of GBM is inter- and intra-tumor heterogeneity. GBM-intrinsic transcriptional profiling has suggested the presence of at least three subtypes of GBM: the proneural, classic, and mesenchymal subtypes. The mesenchymal subtype is the most aggressive, and patients with the mesenchymal subtype of primary and recurrent tumors tend to have a worse prognosis compared with patients with the other subtypes. Furthermore, GBM can shift from other subtypes to the mesenchymal subtype over the course of disease progression or recurrence. This phenotypic transition is driven by diverse tumor-intrinsic molecular mechanisms or microenvironmental factors. Thus, better understanding of the plastic nature of mesenchymal transition in GBM is pivotal to developing new therapeutic strategies. In this review, we provide a comprehensive overview of the current understanding of the elements involved in the mesenchymal transition of GBM and discuss future perspectives. |
Keywords | glioma glioblastoma mesenchymal subtype mesenchymal transition heterogeneity |
Amo Type | Review |
Publication Title | Acta Medica Okayama |
Published Date | 2022-10 |
Volume | volume76 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 489 |
End Page | 502 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 36352795 |
Web of Science KeyUT | 000884907100001 |
FullText URL | fulltext.pdf |
---|---|
Author | Yamada, Hiroshi| Abe, Tadashi| Nagaoka, Hikaru| Takashima, Eizo| Nitta, Ryo| Yamamoto, Masahiro| Takei, Kohji| |
Keywords | IFN-inducible GTPase Irgb6 GTPase membrane T gondii |
Published Date | 2022-09-09 |
Publication Title | Frontiers In Cellular And Infection Microbiology |
Volume | volume12 |
Publisher | Frontiers Media |
Start Page | 992198 |
ISSN | 2235-2988 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 Yamada, Abe, Nagaoka, Takashima, Nitta, Yamamoto and Takei. |
File Version | publisher |
PubMed ID | 36159643 |
DOI | 10.3389/fcimb.2022.992198 |
Web of Science KeyUT | 000873786000001 |
Related Url | isVersionOf https://doi.org/10.3389/fcimb.2022.992198 |
FullText URL | fulltext.pdf |
---|---|
Author | Takagi, Kosei| Murotani, Kenta| Kamoshita, Satoru| Kuroda, Akiyoshi| |
Keywords | Parenteral nutrition Lipid injectable emulsion Medical inpatient Clinical outcome Real-world data |
Published Date | 2022-10-27 |
Publication Title | BMC Medicine |
Volume | volume20 |
Issue | issue1 |
Publisher | BMC |
Start Page | 371 |
ISSN | 1741-7015 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2022. |
File Version | publisher |
PubMed ID | 36289527 |
DOI | 10.1186/s12916-022-02568-x |
Web of Science KeyUT | 000873785800002 |
Related Url | isVersionOf https://doi.org/10.1186/s12916-022-02568-x |
FullText URL | fulltext.pdf |
---|---|
Author | Hayibor, Kennedy Mawunya| Sunatsuki, Yukinari| Suzuki, Takayoshi| |
Keywords | (pyridyl)(imidazolyl)azines aldazines kryptoracemate crystal structure |
Published Date | 2022-10-11 |
Publication Title | Molecules |
Volume | volume27 |
Issue | issue20 |
Publisher | MDPI |
Start Page | 6788 |
ISSN | 1420-3049 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 by the authors. |
File Version | publisher |
PubMed ID | 36296383 |
DOI | 10.3390/molecules27206788 |
Web of Science KeyUT | 000873383100001 |
Related Url | isVersionOf https://doi.org/10.3390/molecules27206788 |
FullText URL | fulltext.pdf |
---|---|
Author | Kawai, Fusako| Furushima, Yoshitomo| Mochizuki, Norihiro| Muraki, Naoki| Yamashita, Mitsuaki| Iida, Akira| Mamoto, Rie| Tosha, Takehiko| Iizuka, Ryo| Kitajima, Sakihito| |
Keywords | Cut190 variant PET hydrolase Micronization Milling PET package PET bottle |
Published Date | 2022-10-26 |
Publication Title | Amb Express |
Volume | volume12 |
Issue | issue1 |
Publisher | Springer |
Start Page | 134 |
ISSN | 2191-0855 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2022. |
File Version | publisher |
PubMed ID | 36289098 |
DOI | 10.1186/s13568-022-01474-y |
Web of Science KeyUT | 000873869500003 |
Related Url | isVersionOf https://doi.org/10.1186/s13568-022-01474-y |
FullText URL | fulltext20221026-3.pdf |
---|---|
Author | Honda, Yasuko| |
Keywords | Community renewable energy rural community local initiative Japan Agricultural Cooperatives energy cooperative |
Note | Journal of Asian Rural Studies, 2021, 5(1): 63-77| |
Published Date | 2021-3-26 |
Publication Title | Journal of Asian Rural Studies |
Volume | volume5 |
Issue | issue1 |
Publisher | Hasanuddin University and Asian Rural Sociology Association |
Start Page | 63 |
End Page | 77 |
ISSN | 2548-3269 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | publisher |
DOI | 10.20956/jars.v5i1.2656 |
Related Url | isVersionOf https://doi.org/10.20956/jars.v5i1.2656 |
FullText URL | fulltext20221017-3.pdf figure20221017-3.pdf |
---|---|
Author | Morizane, Shin| Sunagawa, Ko| Nomura, Hayato| Ouchida, Mamoru| |
Keywords | Atopic dermatitis Serine protease Kallikrein-related peptidases Lympho-epithelial Kazal-type-related inhibitor Protease -activated receptor 2 |
Note | © 2022 Japanese Society for Investigative Dermatology. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jdermsci.2022.06.004] . | This fulltext is available in July 2023.| |
Published Date | 2022-07 |
Publication Title | Journal of Dermatological Science |
Volume | volume107 |
Issue | issue1 |
Publisher | Elsevier BV |
Start Page | 2 |
End Page | 7 |
ISSN | 0923-1811 |
NCID | AA1075636X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 Japanese Society for Investigative Dermatology |
File Version | author |
PubMed ID | 35817663 |
DOI | 10.1016/j.jdermsci.2022.06.004 |
Web of Science KeyUT | 000863858700001 |
Related Url | isVersionOf https://doi.org/10.1016/j.jdermsci.2022.06.004 |
FullText URL | fulltext20221017-2.pdf fig2221017-2.pdf tables20221017-2.pdf |
---|---|
Author | Furumatsu, Takayuki| Miyazawa, Shinichi| Kodama, Yuya| Kamatsuki, Yusuke| Okazaki, Yoshiki| Hiranaka, Takaaki| Okazaki, Yuki| Kintaka, Keisuke| Ozaki, Toshifumi| |
Keywords | Medial meniscus Posterior root tear MMPRT Transtibial pullout repair Clinical outcome |
Note | © 2022 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.knee.2022.08.010] .| This fulltext is available in Sep. 2023.| |
Published Date | 2022-10 |
Publication Title | The Knee |
Volume | volume38 |
Publisher | Elsevier BV |
Start Page | 141 |
End Page | 147 |
ISSN | 0968-0160 |
NCID | AA11534443 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 Elsevier B.V. |
File Version | author |
PubMed ID | 36058121 |
DOI | 10.1016/j.knee.2022.08.010 |
Web of Science KeyUT | 000863705700003 |
Related Url | isVersionOf https://doi.org/10.1016/j.knee.2022.08.010 |
FullText URL | fulltext.pdf |
---|---|
Author | Wang, Dengli| Ousaka, Daiki| Qiao, Handong| Wang, Ziyi| Zhao, Kun| Gao, Shangze| Liu, Keyue| Teshigawara, Kiyoshi| Takada, Kenzo| Nishibori, Masahiro| |
Keywords | intracerebral hemorrhage HMGB1 antibody therapy non-human primate |
Published Date | 2022-09-23 |
Publication Title | Cells |
Volume | volume11 |
Issue | issue19 |
Publisher | MDPI |
Start Page | 2970 |
ISSN | 2073-4409 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 by the authors. |
File Version | publisher |
PubMed ID | 36230933 |
DOI | 10.3390/cells11192970 |
Web of Science KeyUT | 000866922400001 |
Related Url | isVersionOf https://doi.org/10.3390/cells11192970 |
FullText URL | fulltext.pdf |
---|---|
Author | Mochizuki, Yusuke| Yamamoto, Norio| Fujii, Tatsuya| Tomita, Yosuke| |
Keywords | cement augmentation trochanteric fracture intertrochanteric fracture hip fracture proximal femoral fracture cumulated ambulation score mobility ambulance ADL pain |
Published Date | 2022-08-27 |
Publication Title | Journal Of Personalized Medicine |
Volume | volume12 |
Issue | issue9 |
Publisher | MDPI |
Start Page | 1392 |
ISSN | 2075-4426 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 by the authors. |
File Version | publisher |
PubMed ID | 36143177 |
DOI | 10.3390/jpm12091392 |
Web of Science KeyUT | 000859577200001 |
Related Url | isVersionOf https://doi.org/10.3390/jpm12091392 |
FullText URL | fulltext.pdf |
---|---|
Author | Kondo, Yuki| Rikiishi, Kazuhide| Sugimoto, Manabu| |
Keywords | 8-oxo-dGTP nudix hydrolase Oryza sativa transcriptional error UV-C |
Published Date | 2022-09 |
Publication Title | Antioxidants |
Volume | volume11 |
Issue | issue9 |
Publisher | MDPI |
Start Page | 1805 |
ISSN | 2076-3921 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 by the authors. |
File Version | publisher |
PubMed ID | 36139879 |
DOI | 10.3390/antiox11091805 |
Web of Science KeyUT | 000858199700001 |
Related Url | isVersionOf https://doi.org/10.3390/antiox11091805 |
FullText URL | fulltext.pdf |
---|---|
Author | Yang, Guang| |
Keywords | gastric adenocarcinoma of fundic gland microsatellite instability mismatch repair deficiency Wnt/beta-catenin signaling pathway |
Published Date | 2022-08-26 |
Publication Title | Medicine |
Volume | volume101 |
Issue | issue34 |
Publisher | Lippincott Williams & Wilkins |
Start Page | e30311 |
ISSN | 0025-7974 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2022 the Author(s). |
File Version | publisher |
PubMed ID | 36042639 |
DOI | 10.1097/MD.0000000000030311 |
Web of Science KeyUT | 000847532100073 |
Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000030311 |