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Author Maruo, Yukinori| Yoshihara, Kumiko| Irie, Masao| Nagaoka, Noriyuki| Matsumoto, Takuya| Minagi, Shogo|
Keywords acrylate methacrylate CAD/CAM flexural strength shear bond strength
Published Date 2022-10-28
Publication Title Materials
Volume volume15
Issue issue21
Publisher MDPI
Start Page 7564
ISSN 1996-1944
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36363156
DOI 10.3390/ma15217564
Web of Science KeyUT 000881219600001
Related Url isVersionOf https://doi.org/10.3390/ma15217564
FullText URL fulltext.pdf
Author Tsuge, Mitsuru| Kodera, Aya| Sumitomo, Hiromi| Araki, Tooru| Yoshida, Ryuichi| Yasui, Kazuya| Sato, Hiroki| Washio, Yosuke| Washio, Kana| Shigehara, Kenji| Yashiro, Masato| Yagi, Takahito| Tsukahara, Hirokazu|
Keywords Neonatal hemochromatosis Thalassemia Liver transplantation Gestational alloimmune liver disease Case report Hepcidin Ineffective erythropoiesis Growth differentiation factor-15
Published Date 2022-10-29
Publication Title BMC Pediatrics
Volume volume22
Issue issue1
Publisher BMC
Start Page 622
ISSN 1471-2431
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 36309641
DOI 10.1186/s12887-022-03706-3
Web of Science KeyUT 000876287400002
Related Url isVersionOf https://doi.org/10.1186/s12887-022-03706-3
JaLCDOI 10.18926/AMO/64122
FullText URL 76_6_715.pdf
Author Mohammed Zahedul Islam Nizami| Gorduysus, Melahat| Shinoda-Ito, Yuki| Yamamoto, Tadashi| Nishina, Yuta| Takashiba, Shogo| Arias, Zulema|
Abstract The failure of endodontic treatment is directly associated with microbial infection in the root canal or periapical areas. An endodontic sealer that is both bactericidal and biocompatible is essential for the success of root canal treatments. This is one of the vital issues yet to be solved in clinical dental practice. This in vitro study assessed the effectiveness of graphene oxide (GO) composites GO-CaF2 and GO-Ag-CaF2 as endodontic sealer materials. Dentin slices were coated with either the GO-based composites or commonly used root canal sealers (non-eugenol zinc oxide sealer). The coated slices were treated in 0.9% NaCl, phosphate-buffered saline (PBS), and simulated body fluid (SBF) at 37˚C for 24 hours to compare their sealing effect on the dentin surface. In addition, the radiopacity of these composites was examined to assess whether they complied with the requirements of a sealer for good radiographic visualization. Scanning electron microscopy showed the significant sealing capability of the composites as coating materials. Radiographic images confirmed their radiopacity. Mineral deposition indicated their bioactivity, especially of GO-Ag-CaF2, and thus it is potential for regenerative application. They were both previously shown to be bactericidal to oral microbes and cytocompatible with host cells. With such a unique assemblage of critical properties, these GO-based composites show promise as endodontic sealers for protection against reinfection in root canal treatment and enhanced success in endodontic treatment overall.
Keywords bioactive sealer graphene oxide mineral deposition antimicrobial activity radiopacity
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-12
Volume volume76
Issue issue6
Publisher Okayama University Medical School
Start Page 715
End Page 721
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36549774
Web of Science KeyUT 000905195100012
JaLCDOI 10.18926/AMO/64120
FullText URL 76_6_695.pdf
Author Onishi, Hideki| Nouso, Kazuhiro| Takaki, Akinobu| Oyama, Atsushi| Adachi, Takuya| Wada, Nozomu| Takeuchi, Yasuto| Shiraha, Hidenori| Okada, Hiroyuki|
Abstract This study sought to identify factors that are predictive of a therapeutic response to hepatic arterial infusion chemotherapy (HAIC) by focusing on the number of prior transcatheter arterial chemoembolization (TACE) sessions. To determine the parameters predicting a good response to HAIC, we retrospectively analyzed 170 patients with hepatocellular carcinoma (HCC) who received HAIC regimens comprising low-dose cisplatin combined with 5-fluorouracil (LFP) or cisplatin (CDDP) for the first time. In both the LFP and CDDP regimens, the response rates were significantly lower in patients with three or more prior TACE sessions than in those with two or fewer prior TACE sessions (LFP 57% versus 28%; p=0.01, CDDP 27% versus 6%; p=0.01). Multivariable logistic regression analysis revealed that the number of prior TACE sessions (≥ 3) was significantly associated with non-responder status (odds ratio 4.17, 95% Confidence Interval (CI) 1.76-9.86) in addition to the HAIC regimen. Multivariable analysis using the Cox proportional hazards model revealed that a larger number of prior TACE sessions (≥ 3) was a significant risk factor for survival (hazard ratio 1.60, 95% CI 1.12-2.29) in addition to Child-Pugh class, serum alpha-fetoprotein concentration, and maximum diameter of HCC. HCC patients who receive fewer prior TACE sessions (≤ 2) were found to be better responders to HAIC.
Keywords hepatic arterial infusion chemotherapy hepatocellular carcinoma refractory transcatheter arterial chemoembolization
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-12
Volume volume76
Issue issue6
Publisher Okayama University Medical School
Start Page 695
End Page 703
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36549772
Web of Science KeyUT 000905195100010
JaLCDOI 10.18926/AMO/64117
FullText URL 76_6_673.pdf
Author Okazawa-Sakai, Mika| Yamamoto, Yasuko| Futagawa, Mashu| Okamura, Miki| Miyawaki, Satoko| Nishina, Tomohiro| Takehara, Kazuhiro| Kozuki, Toshiyuki| Tomida, Shuta| Hyodo, Ichinosuke| Ohsumi, Shozo| Hirasawa, Akira|
Abstract Patients found to have presumed germline pathogenic variants (PGPVs) during comprehensive genomic profiling (CGP) require genetic counseling (GC) referrals. We retrospectively investigated the outcomes of patients with PGPVs. Among 159 patients who underwent CGP, we recommended GC for the 16 patients with PGPVs (3 with [FG group] and 13 without [G Group] a family/personal history of hereditary cancer) as well as for the 8 patients with no PGPVs, but a history (F group); 2 (67%), 5 (38%), and 3 (38%) patients received GC in the FG, G, and F groups, respectively. Germline testing results were positive in 1 and 2 patients of the FG and G groups, respectively. Among the patients recommended for GC, 58% did not receive GC due to lack of interest, poor performance status, or death. CGP contributes to the identification of germline variants in patients without a history of hereditary cancer. However, the proportion of patients who undergo GC should be improved.
Keywords comprehensive genomic profiling hereditary cancer germline findings presumed germline pathogenic variant(s) genetic counseling
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-12
Volume volume76
Issue issue6
Publisher Okayama University Medical School
Start Page 673
End Page 678
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36549769
Web of Science KeyUT 000905195100007
FullText URL K0006716_abstract_review.pdf K0006716_fulltext.pdf
Author TAKIGAHIRA, Yoshiaki|
Published Date 2022-09-22
Content Type Thesis or Dissertation
Grant Number 甲第6716号
Granted Date 2022-09-22
Thesis Type Doctor of Philosophy in Engineering
Grantor 岡山大学
language Japanese
JaLCDOI 10.18926/AMO/64044
FullText URL 76_5_609.pdf
Author Matsumoto, Ken| Fujishita, Keigo| Matsuda, Masayuki| Oka, Satoshi| Fujisawa, Yuka| Imai, Toshi| Machida, Takuya|
Abstract A 69-year-old Japanese man with acute leukemia received post-transplant cyclophosphamide-based haploidentical stem cell transplantation (PTCY-haplo-SCT) but was readmitted with dyspnea and ground-glass-opacities of the lungs. Bronchoscopy showed inflammatory changes with no signs of infection. He received steroids but required intubation as his condition deteriorated. In addition to antithymocyte globulin and cyclophosphamide, we administered ruxolitinib but failed to save him. Autopsy findings revealed fibrotic nonspecific interstitial pneumonia (NSIP) without evidence of organizing pneumonia or infection. Thus, we diagnosed idiopathic pneumonia syndrome (IPS). As far as our knowledge, this is the first case of IPS with NSIP histology after PTCY-haplo-SCT.
Keywords idiopathic pneumonia syndrome ruxolitinib post-transplant cyclophosphamide-based haploidentical stem cell transplantation nonspecific interstitial pneumonia
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2022-10
Volume volume76
Issue issue5
Publisher Okayama University Medical School
Start Page 609
End Page 615
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36352810
Web of Science KeyUT 000884907100016
FullText URL fulltext.pdf
Author Esumi, Satoru| Ushio, Soichiro| Zamami, Yoshito|
Keywords Alzheimer's disease polypharmacy drug interactions
Published Date 2022-10-13
Publication Title Medicina-Lithuania
Volume volume58
Issue issue10
Publisher MDPI
Start Page 1445
ISSN 1010-660X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36295605
DOI 10.3390/medicina58101445
Web of Science KeyUT 000875259600001
Related Url isVersionOf https://doi.org/10.3390/medicina58101445
JaLCDOI 10.18926/AMO/64024
FullText URL 76_5_489.pdf
Author Matsumoto, Yuji| Ichikawa, Tomotsugu| Kurozumi, Kazuhiko| Date, Isao|
Abstract Glioblastoma (GBM) is a fatal primary malignant brain tumor in adults. Despite decades of research, the prognosis for GBM patients is still disappointing. One major reason for the intense therapeutic resistance of GBM is inter- and intra-tumor heterogeneity. GBM-intrinsic transcriptional profiling has suggested the presence of at least three subtypes of GBM: the proneural, classic, and mesenchymal subtypes. The mesenchymal subtype is the most aggressive, and patients with the mesenchymal subtype of primary and recurrent tumors tend to have a worse prognosis compared with patients with the other subtypes. Furthermore, GBM can shift from other subtypes to the mesenchymal subtype over the course of disease progression or recurrence. This phenotypic transition is driven by diverse tumor-intrinsic molecular mechanisms or microenvironmental factors. Thus, better understanding of the plastic nature of mesenchymal transition in GBM is pivotal to developing new therapeutic strategies. In this review, we provide a comprehensive overview of the current understanding of the elements involved in the mesenchymal transition of GBM and discuss future perspectives.
Keywords glioma glioblastoma mesenchymal subtype mesenchymal transition heterogeneity
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2022-10
Volume volume76
Issue issue5
Publisher Okayama University Medical School
Start Page 489
End Page 502
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36352795
Web of Science KeyUT 000884907100001
FullText URL fulltext.pdf
Author Yamada, Hiroshi| Abe, Tadashi| Nagaoka, Hikaru| Takashima, Eizo| Nitta, Ryo| Yamamoto, Masahiro| Takei, Kohji|
Keywords IFN-inducible GTPase Irgb6 GTPase membrane T gondii
Published Date 2022-09-09
Publication Title Frontiers In Cellular And Infection Microbiology
Volume volume12
Publisher Frontiers Media
Start Page 992198
ISSN 2235-2988
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Yamada, Abe, Nagaoka, Takashima, Nitta, Yamamoto and Takei.
File Version publisher
PubMed ID 36159643
DOI 10.3389/fcimb.2022.992198
Web of Science KeyUT 000873786000001
Related Url isVersionOf https://doi.org/10.3389/fcimb.2022.992198
FullText URL fulltext.pdf
Author Takagi, Kosei| Murotani, Kenta| Kamoshita, Satoru| Kuroda, Akiyoshi|
Keywords Parenteral nutrition Lipid injectable emulsion Medical inpatient Clinical outcome Real-world data
Published Date 2022-10-27
Publication Title BMC Medicine
Volume volume20
Issue issue1
Publisher BMC
Start Page 371
ISSN 1741-7015
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 36289527
DOI 10.1186/s12916-022-02568-x
Web of Science KeyUT 000873785800002
Related Url isVersionOf https://doi.org/10.1186/s12916-022-02568-x
FullText URL fulltext.pdf
Author Hayibor, Kennedy Mawunya| Sunatsuki, Yukinari| Suzuki, Takayoshi|
Keywords (pyridyl)(imidazolyl)azines aldazines kryptoracemate crystal structure
Published Date 2022-10-11
Publication Title Molecules
Volume volume27
Issue issue20
Publisher MDPI
Start Page 6788
ISSN 1420-3049
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36296383
DOI 10.3390/molecules27206788
Web of Science KeyUT 000873383100001
Related Url isVersionOf https://doi.org/10.3390/molecules27206788
FullText URL fulltext.pdf
Author Kawai, Fusako| Furushima, Yoshitomo| Mochizuki, Norihiro| Muraki, Naoki| Yamashita, Mitsuaki| Iida, Akira| Mamoto, Rie| Tosha, Takehiko| Iizuka, Ryo| Kitajima, Sakihito|
Keywords Cut190 variant PET hydrolase Micronization Milling PET package PET bottle
Published Date 2022-10-26
Publication Title Amb Express
Volume volume12
Issue issue1
Publisher Springer
Start Page 134
ISSN 2191-0855
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 36289098
DOI 10.1186/s13568-022-01474-y
Web of Science KeyUT 000873869500003
Related Url isVersionOf https://doi.org/10.1186/s13568-022-01474-y
FullText URL fulltext20221026-3.pdf
Author Honda, Yasuko|
Keywords Community renewable energy rural community local initiative Japan Agricultural Cooperatives energy cooperative
Note Journal of Asian Rural Studies, 2021, 5(1): 63-77|
Published Date 2021-3-26
Publication Title Journal of Asian Rural Studies
Volume volume5
Issue issue1
Publisher Hasanuddin University and Asian Rural Sociology Association
Start Page 63
End Page 77
ISSN 2548-3269
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version publisher
DOI 10.20956/jars.v5i1.2656
Related Url isVersionOf https://doi.org/10.20956/jars.v5i1.2656
FullText URL fulltext20221017-3.pdf figure20221017-3.pdf
Author Morizane, Shin| Sunagawa, Ko| Nomura, Hayato| Ouchida, Mamoru|
Keywords Atopic dermatitis Serine protease Kallikrein-related peptidases Lympho-epithelial Kazal-type-related inhibitor Protease -activated receptor 2
Note © 2022 Japanese Society for Investigative Dermatology. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jdermsci.2022.06.004] . | This fulltext is available in July 2023.|
Published Date 2022-07
Publication Title Journal of Dermatological Science
Volume volume107
Issue issue1
Publisher Elsevier BV
Start Page 2
End Page 7
ISSN 0923-1811
NCID AA1075636X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Japanese Society for Investigative Dermatology
File Version author
PubMed ID 35817663
DOI 10.1016/j.jdermsci.2022.06.004
Web of Science KeyUT 000863858700001
Related Url isVersionOf https://doi.org/10.1016/j.jdermsci.2022.06.004
FullText URL fulltext20221017-2.pdf fig2221017-2.pdf tables20221017-2.pdf
Author Furumatsu, Takayuki| Miyazawa, Shinichi| Kodama, Yuya| Kamatsuki, Yusuke| Okazaki, Yoshiki| Hiranaka, Takaaki| Okazaki, Yuki| Kintaka, Keisuke| Ozaki, Toshifumi|
Keywords Medial meniscus Posterior root tear MMPRT Transtibial pullout repair Clinical outcome
Note © 2022 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.knee.2022.08.010] .| This fulltext is available in Sep. 2023.|
Published Date 2022-10
Publication Title The Knee
Volume volume38
Publisher Elsevier BV
Start Page 141
End Page 147
ISSN 0968-0160
NCID AA11534443
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Elsevier B.V.
File Version author
PubMed ID 36058121
DOI 10.1016/j.knee.2022.08.010
Web of Science KeyUT 000863705700003
Related Url isVersionOf https://doi.org/10.1016/j.knee.2022.08.010
FullText URL fulltext.pdf
Author Wang, Dengli| Ousaka, Daiki| Qiao, Handong| Wang, Ziyi| Zhao, Kun| Gao, Shangze| Liu, Keyue| Teshigawara, Kiyoshi| Takada, Kenzo| Nishibori, Masahiro|
Keywords intracerebral hemorrhage HMGB1 antibody therapy non-human primate
Published Date 2022-09-23
Publication Title Cells
Volume volume11
Issue issue19
Publisher MDPI
Start Page 2970
ISSN 2073-4409
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36230933
DOI 10.3390/cells11192970
Web of Science KeyUT 000866922400001
Related Url isVersionOf https://doi.org/10.3390/cells11192970
FullText URL fulltext.pdf
Author Mochizuki, Yusuke| Yamamoto, Norio| Fujii, Tatsuya| Tomita, Yosuke|
Keywords cement augmentation trochanteric fracture intertrochanteric fracture hip fracture proximal femoral fracture cumulated ambulation score mobility ambulance ADL pain
Published Date 2022-08-27
Publication Title Journal Of Personalized Medicine
Volume volume12
Issue issue9
Publisher MDPI
Start Page 1392
ISSN 2075-4426
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36143177
DOI 10.3390/jpm12091392
Web of Science KeyUT 000859577200001
Related Url isVersionOf https://doi.org/10.3390/jpm12091392
FullText URL fulltext.pdf
Author Kondo, Yuki| Rikiishi, Kazuhide| Sugimoto, Manabu|
Keywords 8-oxo-dGTP nudix hydrolase Oryza sativa transcriptional error UV-C
Published Date 2022-09
Publication Title Antioxidants
Volume volume11
Issue issue9
Publisher MDPI
Start Page 1805
ISSN 2076-3921
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36139879
DOI 10.3390/antiox11091805
Web of Science KeyUT 000858199700001
Related Url isVersionOf https://doi.org/10.3390/antiox11091805
FullText URL fulltext.pdf
Author Yang, Guang|
Keywords gastric adenocarcinoma of fundic gland microsatellite instability mismatch repair deficiency Wnt/beta-catenin signaling pathway
Published Date 2022-08-26
Publication Title Medicine
Volume volume101
Issue issue34
Publisher Lippincott Williams & Wilkins
Start Page e30311
ISSN 0025-7974
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 the Author(s).
File Version publisher
PubMed ID 36042639
DOI 10.1097/MD.0000000000030311
Web of Science KeyUT 000847532100073
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000030311