result 334 件
| JaLCDOI | 10.18926/14955 |
|---|---|
| Title Alternative | 気管支喘息患者における努力肺活量(% FVC)の低下と気道炎症ならびに臨床病型との関連 |
| FullText URL | 069_028_034.pdf |
| Author | Mitsunobu, Fumihiro| Mifune, Takashi| Hosaki, Yasuhiro| Ashida, Kozo| Yokota, Satoshi| Tsugeno, Hirofumi| Tanizaki, Yoshiro| Ochi, Koji| Harada, Hideo| |
| Abstract | Clinical features of asthmatics with a low % FVC (<80%) were studied in relation to airway inflammation and clinical asthma types. 1. Twenty four (75.0%) of the 32 subjects with a low % FVC had steroid-dependent intractable asthma. 2. A significant association between % FVC value and clinical asthma type was found. The value of % FVC was significantly lower in subjects with type II asthma (bronchiolar obstruction), in which significantly decreased proportion of lymphocytes,and significantly increased proportion of neutrophils in bronchoalveolar lavage (BAL) fluid were observed, than in those with type la-1 (simple bronchoconstriction) with (P<0.001) and without glucocorticoid therapy (P<0.02). 3. The % FVC value was significantly improved after treatment in type lb (hypersecretion) with BAL eosinophilia, but not in those with type II with BAL neutrophilia. These results demonstrate that marked decrease of % FVC in patients with asthma correlated with airway inflammation, and that airway reversibility by medication is very low in patients with type II asthma. |
| Keywords | ventilatory function FEV1.0 bronchoalveolar lavage bronchial reversibility |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 1998-12 |
| Volume | volume69 |
| Start Page | 28 |
| End Page | 34 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308252 |
| JaLCDOI | 10.18926/14835 |
|---|---|
| Title Alternative | 気管支喘息における気管支肺胞洗浄液中の細胞成分に対する加齢および副腎皮質ホルモンの影響 |
| FullText URL | 72_016_022.pdf |
| Author | Mitsunobu, Fumihiro| Hosaki, Yasuhiro| Ashida, Kozo| Tsugeno, Hirofumi| Okamoto, Makoto| Nishida, Norikazu| Takata, Shingo| Yokoi, Tadashi| Tanizaki, Yoshiro| |
| Abstract | Effects of aging and glucocorticoid therapy on bronchoalveolar lavage (BAL) cells, particularly lymphocytes, neutrophils and eosinophils, were examined in 81 patients with asthma. 1. The proportion of BAL lymphocytes tended to increase with aging in asthmatics under age 69 years, and the proportion was significantly higher in patients with asthma between the ages of 60 and 69 than in those under age 39 and between the ages of 40 and 49. 2. The proportions of BAL neutrophils and eosinophils were not related to aging. 3. The proportion of BAL lymphocytes was higher in patients without glucocorticoid therapy than in those with steroid-dependent intractable asthma (SOIA) in those under age 69 years. In patients between the ages of 50 and 59, the proportion of BAL lymphocytes was significantly higher in patients without glucocorticoids than in those with SOIA. 4. The proportion of BAL neutrophils was higher in patients without glucocorticoid therapy than in those with SOIA, and the difference was significant in patients between the ages of 60 and 69. 5. The proportion of BAL eosinophils was not related to glucocorticoid therapy. These results suggest that the proportion of BAL lymphocytes and neutrophils is affected by aging and glucocorticoid therapy, but not BAL eosinophils. |
| Keywords | aging asthma glucocorticoid therapy BAL cells |
| Publication Title | 岡大三朝分院研究報告 |
| Published Date | 2002-02-01 |
| Volume | volume72 |
| Start Page | 16 |
| End Page | 22 |
| ISSN | 0918-7839 |
| language | English |
| File Version | publisher |
| NAID | 120002308605 |
| JaLCDOI | 10.18926/14775 |
|---|---|
| Title Alternative | A case of anti - neutrophil cytoplasmic autoantibody-associated vasculitis: Resolution after early diagnosis |
| FullText URL | 73_088_092.pdf |
| Author | Ichikawa, Hirohisa| Ashida, Kozo| Ono, Katsuichiro| Takata, Shingo| Yokoi, Tadashi| Nagata, Takuya| Okamoto, Makoto| Tsugeno, Hirohumi| Nishida, Norikazu| Hosaki, Yasuhiro| Mitsunobu, Fumihiro| Tanizaki, Yoshiro| Noguchi, Yoshinori| Tanimoto, Mitsune| |
| Abstract | 症例は76歳男性03年前肺気腫と診断された｡今回呼吸器リハビリテーション目的で当院に入院の運びとなった｡入院時より37-38'Cの発熱を認め,下気道感染を疑い抗生剤で加療したが改善しなかった.入院時の検尿検査で蛋白･潜血陽性であり,血清MPO-ANCAが307U/mlと高値を示した｡血清クレアチニン値も徐々に上昇してきたため,MPO-ANCA関連血管炎と診断した.プレドニゾロン投与を開始したところ,症状及び検査所見は速やかに改善した. |
| Keywords | ANCA関連血管炎 早期診断 顕微鏡的多発血管炎 |
| Publication Title | 岡大三朝医療センター研究報告 |
| Published Date | 2003-02-01 |
| Volume | volume73 |
| Start Page | 88 |
| End Page | 92 |
| ISSN | 1348-1258 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002308580 |
| Author | Okatani, Teruta| |
|---|---|
| Published Date | 1966-09-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume78 |
| Issue | issue7-9 |
| Content Type | Journal Article |
| Author | Suzaki, Masanori| |
|---|---|
| Published Date | 1966-05-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume78 |
| Issue | issue4-5 |
| Content Type | Journal Article |
| Author | Morimoto, Setsuo| |
|---|---|
| Published Date | 1966-05-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume78 |
| Issue | issue4-5 |
| Content Type | Journal Article |
| Author | Kotsuka, Takashi| |
|---|---|
| Published Date | 1966-03-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume78 |
| Issue | issue2-3 |
| Content Type | Journal Article |
| Author | Kotsuka, Takashi| |
|---|---|
| Published Date | 1966-03-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume78 |
| Issue | issue2-3 |
| Content Type | Journal Article |
| Author | Katano, Takashi| |
|---|---|
| Published Date | 1966-01-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume78 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Katano, Takashi| |
|---|---|
| Published Date | 1966-01-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume78 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Yamada, Yukio| |
|---|---|
| Published Date | 1991 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume103 |
| Issue | issue11-12 |
| Content Type | Journal Article |
| Author | Yokoyama, Nobuji| |
|---|---|
| Published Date | 1990-02 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume102 |
| Issue | issue1-2 |
| Content Type | Journal Article |
| Author | Ishibashi, Ken| |
|---|---|
| Published Date | 1991 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume103 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Ishibashi, Ken| |
|---|---|
| Published Date | 1991 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume103 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Yokota, Satoshi| |
|---|---|
| Published Date | 1992 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume104 |
| Issue | issue5-6 |
| Content Type | Journal Article |
| Author | Nishimura, Masataka| |
|---|---|
| Published Date | 1991 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume103 |
| Issue | issue11-12 |
| Content Type | Journal Article |
| Author | Nakayama, Kengo| |
|---|---|
| Published Date | 1992 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume104 |
| Issue | issue5-6 |
| Content Type | Journal Article |
| Author | Nakayama, Kengo| |
|---|---|
| Published Date | 1992 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume104 |
| Issue | issue5-6 |
| Content Type | Journal Article |
| Author | Fujita, Michio| |
|---|---|
| Published Date | 1992 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume104 |
| Issue | issue3-4 |
| Content Type | Journal Article |
| Author | Kuroda, Masahiro| Hiraki, Yoshio| Kawasaki, Shouji| |
|---|---|
| Published Date | 1991-08 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume103 |
| Issue | issue7-8 |
| Content Type | Journal Article |
