result 777 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Inoguchi, Kyosuke| Hongo, Takashi| Naito, Hiromichi| Nakao, Atsunori| |
| Keywords | sepsis pelvic abscess conservative treatment neurogenic bladder bladder rupture |
| Published Date | 2021-10-19 |
| Publication Title | Cureus |
| Volume | volume13 |
| Issue | issue10 |
| Publisher | CUREUS INC |
| Start Page | e18913 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Inoguchi et al. |
| File Version | publisher |
| DOI | 10.7759/cureus.18913 |
| Web of Science KeyUT | 000709915500003 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.18913 |
| JaLCDOI | 10.18926/AMO/62814 |
|---|---|
| FullText URL | 75_6_735.pdf |
| Author | Nagai, Yasuo| Takagi, Kosei| Kuise, Takashi| Umeda, Yuzo| Yoshida, Ryuichi| Yoshida, Kazuhiro| Yasui, Kazuya| Yagi, Takahito| Fujiwara, Toshiyoshi| |
| Abstract | Surgical intervention for hepatolithiasis following hepaticojejunostomy (HJ) has rarely been reported. Herein, we present a case of post-HJ multiple hepatolithiasis treated with left hemihepatectomy with double HJ reconstruction. A 72-year-old woman who had undergone HJ for iatrogenic bile duct injury developed repeated cholangitis due to complicated hepatolithiasis accompanied by an atrophied left hepatic lobe and HJ stricture. Since endoscopic intervention was unsuccessful, the patient underwent left hemihepatectomy with HJ re-anastomoses of the common hepatic duct and left hepatic duct (double HJ technique). The double HJ technique with hepatectomy can be a useful option for treating complicated hepatolithiasis following HJ. |
| Keywords | hepatolithiasis hepaticojejunostomy hepatectomy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 735 |
| End Page | 739 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955542 |
| Web of Science KeyUT | 000735297900009 |
| NAID | 120007180278 |
| JaLCDOI | 10.18926/AMO/62809 |
|---|---|
| FullText URL | 75_6_699.pdf |
| Author | Kawano, Tetsuya| Miyakoshi, Naohisa| Tsuchie, Hiroyuki| Kashiwagura, Takeshi| Kobayashi, Moto| Aonuma, Hiroshi| Sugimura, Yusuke| Shimada, Yoichi| |
| Abstract | Glucocorticoid-induced osteoporosis (GIOP) is one of the side effects associated with glucocorticoid (GC) therapy. In 2014, the Japanese Society for Bone and Mineral Research (JSBMR) provided new guidelines for the management and treatment of GIOP. The aim of the present study was to clarify the prevalence of patients with rheumatoid arthritis (RA) requiring treatment according to the new guidelines and to identify risk factors associated with lack of treatment in these patients. Patients in the 2018 Akita Orthopedic group on Rheumatoid Arthritis (AORA) database were enrolled. Of 2,234 patients with RA in the database, 683 (30.6%) met the 2014 JSBMR guideline treatment criteria, and 480 (70.3%) had been treated. The untreated group included a larger number of males, younger patients, and patients treated in clinics rather than hospital (p<0.001, p=0.015, and p<0.001, respectively). Multivariate analyses found that male sex, younger age, and clinic-based RA care were significant risk factors associated with lack of treatment (p<0.001, p=0.013, and p<0.001, respectively). Thus, male sex, younger age, and clinic-based care were identified as risk factors |
| Keywords | glucocorticoid glucocorticoid-induced osteoporosis rheumatoid arthritis osteoporosis osteopenia |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 699 |
| End Page | 704 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955537 |
| Web of Science KeyUT | 000735297900005 |
| NAID | 120007180283 |
| FullText URL | mjou_064_117_141.pdf |
|---|---|
| Author | Wang, Qi| |
| Abstract | As the first attempt to classify τ-tilting finite two-point algebras, we have determined the τ-tilting finiteness for minimal wild two-point algebras and some tame two-point algebras. |
| Keywords | Support τ-tilting modules τ-tilting finite two-point algebras |
| Published Date | 2022-01 |
| Publication Title | Mathematical Journal of Okayama University |
| Volume | volume64 |
| Issue | issue1 |
| Publisher | Department of Mathematics, Faculty of Science, Okayama University |
| Start Page | 117 |
| End Page | 141 |
| ISSN | 0030-1566 |
| NCID | AA00723502 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright ©2022 by the Editorial Board of Mathematical Journal of Okayama University |
| FullText URL | fulltext20211015-1.pdf |
|---|---|
| Author | Morita, Hiroshi| Miyamoto, Masakazu| |
| Keywords | Brugada syndrome Early repolarization syndrome J wave syndrome |
| Note | © 2021 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.tcm.2021.08.003] .| |
| Published Date | 2021-08-10 |
| Publication Title | Trends in Cardiovascular Medicine |
| Publisher | Elsevier Inc. |
| Start Page | 1 |
| ISSN | 10501738 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Elsevier Inc. All rights reserved. |
| File Version | author |
| PubMed ID | 34389408 |
| DOI | 10.1016/j.tcm.2021.08.003 |
| Related Url | isVersionOf https://doi.org/10.1016/j.tcm.2021.08.003 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kobayashi, Kazuki| Yukiue, Tadato| Yoshida, Hideyuki| Tsuboi, Nobushige| Takahashi, Yuu| Makino, Keigo| Kimura, Ryu| Mizuta, Ryo| Sasada, Susumu| Ogawa, Tomoyuki| Nagayama, Noriyuki| Yasuhara, Takao| Date, Isao| |
| Keywords | artificial bone cranioplasty finite element analyses ultra-high-molecular-weight polyethylene |
| Published Date | 2021 |
| Publication Title | Neurologia Medico-Chirurgica |
| Volume | volume61 |
| Issue | issue9 |
| Publisher | The Japan Neurosurgical Society |
| Start Page | 549 |
| End Page | 556 |
| ISSN | 0470-8105 |
| NCID | AN00358613 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Japan Neurosurgical Society |
| File Version | publisher |
| PubMed ID | 34092749 |
| DOI | 10.2176/nmc.oa.2021-0032 |
| Web of Science KeyUT | 000697159800006 |
| Related Url | isVersionOf https://doi.org/10.2176/nmc.oa.2021-0032 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ikegawa, Shuntaro| Matsuoka, Ken-ichi| |
| Keywords | regulatory T cell graft-versus-host disease interleukin 2 immune checkpoint inhibitor post-transplant cyclophosphamide |
| Published Date | 2021-08-30 |
| Publication Title | Frontiers In Immunology |
| Volume | volume12 |
| Publisher | Frontiers Media SA |
| Start Page | 713358 |
| ISSN | 1664-3224 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Ikegawa and Matsuoka. |
| File Version | publisher |
| PubMed ID | 34526990 |
| DOI | 10.3389/fimmu.2021.713358 |
| Web of Science KeyUT | 000698797000001 |
| Related Url | isVersionOf https://doi.org/10.3389/fimmu.2021.713358 |
| JaLCDOI | 10.18926/AMO/62402 |
|---|---|
| FullText URL | 75_4_495.pdf |
| Author | Sugiyama, Shuntaro| Iida, Takatoshi| Morimoto, Yoshinari| Yamazaki, Yuki| Mikuzuki, Lou| Hayashi, Megumi| |
| Abstract | Tablet size and head posture have been reported to affect swallowing of medications, but no previous studies have evaluated their effects in detail. Our aim was to investigate for the first time the effect of tablet size and head posture on drug swallowing by endoscopic evaluation in healthy subjects. Round tablets (7 , 10 , 12, and 14 mm in diameter) were swallowed by 15 healthy adults with an endoscope inserted in the neutral, head flex-ion, and head extension positions. Evaluation of swallowing difficulty using a numeric rating scale (NRS), presence or absence of pharyngeal residue and its location, and tablet oral transit time (TOTT) were recorded. In the neutral position, the NRS score was higher with the 14 mm tablets than with the 7 mm tablets. The TOTT with the 7 mm tablets was significantly shorter in the head extension than in the neutral position. Swallowing difficulty increased when the tablet diameter was more than 7 mm. Residues were found in the epi-glottis, pyriform sinus, and tongue base. These findings suggest that head extension shortens the TOTT and assists oral-pharyngeal transport. |
| Keywords | tablet size head posture swallowing endoscopy pharyngeal residue |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 495 |
| End Page | 503 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511617 |
| Web of Science KeyUT | 000709282300003 |
| NAID | 120007146045 |
| JaLCDOI | 10.18926/AMO/62399 |
|---|---|
| FullText URL | 75_4_471.pdf |
| Author | Iwamuro, Masaya| Toyokawa, Tatsuya| Matsueda, Kazuhiro| Hori, Shinichiro| Yoshioka, Masao| Moritou, Yuki| Tanaka, Takehiro| Mizuno, Motowo| Okada, Hiroyuki| |
| Abstract | The characteristics of gastric polyps in patients with Peutz-Jeghers (PJ) syndrome (PJS) have not been fully investigated. The objective of this study was to reveal the endoscopic and pathologic findings of gastric polyps in patients with PJS. We reviewed 11 patients with PJS treated at 6 institutions, and summarized the endo-scopic and pathologic features of their gastric polyps. The polyps were mainly classified into 2 types: (i) soli-tary or sporadic polyps > 5 mm, reddish in color with a sessile or semi-pedunculated morphology (n = 9); and (ii) multiple sessile polyps ≤ 5 mm with the same color tone as the peripheral mucosa (n = 9). Patients who underwent endoscopic mucosal resection for polyps > 5 mm were diagnosed with PJ polyps (n = 2), whereas those who underwent biopsy were diagnosed with hyperplastic polyps. Polyps ≤ 5 mm were pathologically diagnosed as fundic gland polyps or hyperplastic polyps. This study revealed that patients with PJS present with 2 types of polyps in the stomach. Endoscopic mucosal resection of polyps > 5 mm seems necessary for the pathologic diagnosis of PJ polyps. |
| Keywords | Peutz-Jeghers syndrome esophagogastroduodenoscopy gastric polyps |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 471 |
| End Page | 477 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511614 |
| Web of Science KeyUT | 000701717000001 |
| NAID | 120007146042 |
| JaLCDOI | 10.18926/AMO/62398 |
|---|---|
| FullText URL | 75_4_461.pdf |
| Author | Murakami, Hiroyuki| Yoshioka, Takanori| Moriyama, Takashi| Ishikawa, Tatsunori| Makita, Masanori| Sunami, Kazutaka| |
| Abstract | Bendamustine plus rituximab (B-R) is an effective therapy for relapsed or refractory (r/r) low-grade B-cell lymphoma (LGBCL) and mantle cell lymphoma (MCL); however, clinical data from Japanese patients treated with B-R therapy are limited. We retrospectively evaluated the efficacy and safety of B-R therapy in 42 patients who received B-R therapy at our hospital for r/r LGBCL and MCL. All patients received intravenous (IV) ritux-imab 375 mg/m2 on day 1 and IV bendamustine 90 mg/m2 on days 2 and 3 every 28 days for up to 6 cycles. The common histologic subtypes were follicular lymphoma (n = 29, 70%), marginal zone lymphoma (n = 6, 14%), and MCL (n = 5, 12%). The overall response rate was 93%, with 62% complete response and complete response unconfirmed. The median progression-free survival (PFS) was 38 months (95% confidence interval [CI], 24.6 to not reached [NR]), and the median overall survival (OS) was 80 months (95% CI, 60.7 to NR). Patients receiving a cumulative dose of bendamustine ≥ 720 mg/m2 showed a significantly longer PFS and OS. Grade 3/4 adverse events (≥ 10%) included neutropenia (55%), lymphopenia (69%), and nausea (24%). B-R therapy was effective and well tolerated, and the cumulative dose of bendamustine was associated with a favorable outcome. |
| Keywords | bendamustine low grade B-cell lymphoma mantle cell lymphoma |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 461 |
| End Page | 469 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511613 |
| Web of Science KeyUT | 000697944600008 |
| NAID | 120007146041 |
| JaLCDOI | 10.18926/AMO/62378 |
|---|---|
| FullText URL | 75_4_403.pdf |
| Author | Matoba, Ryo| Morizane, Yuki| |
| Abstract | Epiretinal membrane (ERM) is a common retinal disease characterized by cellular proliferation and metaplasia that lead to the formation of a pathological fibrocellular membrane immediately superjacent to the inner retinal surface. The vast majority of ERMs are considered idiopathic. However, ERM formation can result from various primary intraocular diseases, including retinal breaks and detachment, retinal vascular diseases, and vitreoretinal inflammatory conditions. Although ERMs are generally asymptomatic or cause mild metamorphopsia and/or a modest decrease in visual acuity, some can cause severe macular distortion and macular edema, resulting in significantly impaired function. Surgical removal of ERM is the only treatment, and improvements in vitrectomy systems have enabled less invasive treatment. However, there are currently no standardized criteria for ERM surgery, and the indications for surgery are determined from the patient’s subjective symptoms. Another problem with ERM surgery is that not all patients show satisfactory postoperative recovery of visual function. Thus, further research is needed to determine the criteria for ERM surgery and methods to improve the postoperative prognosis. |
| Keywords | epiretinal membrane vitrectomy optical coherence tomography internal limiting membrane lamellar macular hole |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 403 |
| End Page | 413 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511606 |
| Web of Science KeyUT | 000697944600001 |
| NAID | 120007146059 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Miyoshi, Toru| Ito, Hiroshi| Shirai, Kohji| Horinaka, Shigeo| Higaki, Jitsuo| Yamamura, Shigeo| Saiki, Atsuhito| Takahashi, Mao| Masaki, Mitsuru| Okura, Takafumi| Kotani, Kazuhiko| Kubozono, Takuro| Yoshioka, Ryo| Kihara, Hajime| Hasegawa, Koji| Satoh-Asahara, Noriko| Orimo, Hajime| |
| Keywords | arterial stiffness blood pressure cardiovascular events pulse-wave velocity risk factor |
| Published Date | 2021-08-17 |
| Publication Title | Journal of The American Heart ASSOCIATION |
| Volume | volume10 |
| Issue | issue16 |
| Publisher | Wiley |
| Start Page | e020103 |
| ISSN | 2047-9980 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 34369198 |
| DOI | 10.1161/JAHA.120.020103 |
| Web of Science KeyUT | 000685396200026 |
| Related Url | isVersionOf https://doi.org/10.1161/JAHA.120.020103 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Obata, Taisuke| Tsutsumi, Koichiro| Kato, Hironari| Ueki, Toru| Miyamoto, Kazuya| Yamazaki, Tatsuhiro| Matsumi, Akihiro| Fujii, Yuki| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Yasugi, Kengo| Ogawa, Tsuneyoshi| Takenaka, Ryuta| Okada, Hiroyuki| |
| Keywords | bile duct stone endoscopic retrograde cholangiography Roux-en-Y anastomosis short-type balloon enteroscopy complete stone removal gastrectomy |
| Published Date | 2021-07-27 |
| Publication Title | Journal of Clinical Medicine |
| Volume | volume10 |
| Issue | issue15 |
| Publisher | MDPI |
| Start Page | 3314 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34362098 |
| DOI | 10.3390/jcm10153314 |
| Web of Science KeyUT | 000682079900001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm10153314 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Omori, Haruka| Shan, Qiusheng| Takabatake, Kiyofumi| Nakano, Keisuke| Kawai, Hotaka| Sukegawa, Shintaro| Tsujigiwa, Hidetsugu| Nagatsuka, Hitoshi| |
| Keywords | gingival ligament tissue-derived stromal cells periodontal ligament tissue-derived stromal cells oral squamous cell carcinoma tumor microenvironment biological character |
| Published Date | 2021-07-12 |
| Publication Title | Cancers |
| Volume | volume13 |
| Issue | issue14 |
| Publisher | MDPI |
| Start Page | 3491 |
| ISSN | 2072-6694 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34298705 |
| DOI | 10.3390/cancers13143491 |
| Web of Science KeyUT | 000676184700001 |
| Related Url | isVersionOf https://doi.org/10.3390/cancers13143491 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nishii, Nobuhiro| Noda, Takashi| Nitta, Takashi| Aizawa, Yoshifusa| Ohe, Tohru| Kurita, Takashi| |
| Keywords | Nippon storm study Implantable cardioverter-defibrillator Cardiac resynchronization therapy with defibrillator Inappropriate ICD therapy |
| Published Date | 2021-06 |
| Publication Title | IJC Heart & Vasculature |
| Volume | volume34 |
| Publisher | Elsevier Ireland Ltd |
| Start Page | 100779 |
| ISSN | 2352-9067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 33997254 |
| DOI | 10.1016/j.ijcha.2021.100779 |
| Web of Science KeyUT | 000667480400049 |
| Related Url | isVersionOf https://doi.org/10.1016/j.ijcha.2021.100779 |
| FullText URL | fulltext20210727-2.pdf |
|---|---|
| Author | Shiotani, Toshio| Sugimoto, Seiichiro| Yamamoto, Haruchika| Miyoshi, Kentaroh| Otani, Shinji| Suzawa, Ken| Yamamoto, Hiromasa| Okazaki, Mikio| Yamane, Masaomi| Toyooka, Shinichi| |
| Keywords | chronic lung allograft dysfunction emphysema irisin living-donor lung transplantation |
| Note | This is a post-peer-review, pre-copyedit version of an article published in Surgery Today. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00595-021-02339-w This fulltext is available in July 2022.| |
| Published Date | 2021-7-12 |
| Publication Title | Surgery Today |
| Volume | volume52 |
| Issue | issue2 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 294 |
| End Page | 305 |
| ISSN | 0941-1291 |
| NCID | AA10824685 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Springer Nature Singapore Pte Ltd. 2021 |
| File Version | author |
| PubMed ID | 34251508 |
| DOI | 10.1007/s00595-021-02339-w |
| Web of Science KeyUT | 000672249200001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00595-021-02339-w |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Obata, Taisuke| Matsumoto, Kazuyuki| Kato, Hironari| Yamazaki, Tatsuhiro| Fujii, Yuki| Tomoda, Takeshi| Horiguchi, Shigeru| Okada, Hiroyuki| |
| Keywords | hemosuccus pancreaticus IPMN pseudoancurysm anticoagulation drug |
| Published Date | 2021-07-01 |
| Publication Title | Internal Medicine |
| Volume | volume60 |
| Issue | issue13 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 2033 |
| End Page | 2038 |
| ISSN | 0918-2918 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 33551406 |
| DOI | 10.2169/internalmedicine.6445-20 |
| Web of Science KeyUT | 000670413600007 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.6445-20 |
| JaLCDOI | 10.18926/AMO/62220 |
|---|---|
| FullText URL | 75_3_289.pdf |
| Author | Miyamoto, Masakazu| Osawa, Kazuhiro| Miyoshi, Toru| Mori, Atsushi| Yoshikawa, Masaki| Oka, Takefumi| Ichikawa, Keishi| Nakamura, Kazufumi| Ito, Hiroshi| |
| Abstract | Early treatment with an oral β-blocker is recommended in patients with a ST-segment–elevation myocardial infarction (STEMI). In this multicenter study, we evaluated the effects of a continuous administration of landiolol, an ultrashort-acting β-blocker, before primary percutaneous coronary intervention (PCI) on myocardial salvage and its safety in STEMI patients. A total of 47 Japanese patients with anterior or lateral STEMI undergoing a primary PCI within 12 h of symptom onset were randomized to receive intravenous landiolol (started at 3 μg/min/kg dose and continued to a total of 50 mg; n=23) or not (control; n=24). Patients with Killip class III or more were excluded. The primary outcome was the myocardial salvage index on cardiac magnetic resonance imaging (MRI) performed 5-7 days after the PCI. Cardiac MRI was performed in 35 patients (74%). The myocardial salvage index in the landiolol group was significantly greater than that in the control group (44.4±14.6% vs. 31.7±18.9%, respectively; p=0.04). There were no significant differences in adverse events at 24 h between the landiolol and control groups. A continuous administration of landiolol before a primary PCI may increase the degree of myocardial salvage without additional hemodynamic adverse effects within the first 24 h after STEMI. |
| Keywords | myocardial infarction landiolol magnetic resonance imaging STEMI PCI |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 289 |
| End Page | 297 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176932 |
| Web of Science KeyUT | 000667147700004 |
| NAID | 120007089835 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Adachi, Takuya| Takeuchi, Yasuto| Takaki, Akinobu| Oyama, Atsushi| Wada, Nozomu| Onishi, Hideki| Shiraha, Hidenori| Okada, Hiroyuki| |
| Keywords | tolvaptan liver cirrhosis ascites |
| Published Date | 2021-05-25 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume22 |
| Issue | issue11 |
| Publisher | MDPI |
| Start Page | 5582 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34070416 |
| DOI | 10.3390/ijms22115582 |
| NAID | 120007089839 |
| Web of Science KeyUT | 000660134900001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms22115582 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mise, Koki| Imamura, Mariko| Yamaguchi, Satoshi| Watanabe, Mayu| Higuchi, Chigusa| Katayama, Akihiro| Miyamoto, Satoshi| Uchida, Haruhito A.| Nakatsuka, Atsuko| Eguchi, Jun| Hida, Kazuyuki| Nakato, Tatsuaki| Tone, Atsuhito| Teshigawara, Sanae| Matsuoka, Takashi| Kamei, Shinji| Murakami, Kazutoshi| Shimizu, Ikki| Miyashita, Katsuhiro| Ando, Shinichiro| Nunoue, Tomokazu| Yoshida, Michihiro| Yamada, Masao| Shikata, Kenichi| Wada, Jun| |
| Keywords | cardiovascular event diabetes lectins N-glycans urinary biomarkers |
| Published Date | 2021-05-24 |
| Publication Title | Frontiers In Cardiovascular Medicine |
| Volume | volume8 |
| Publisher | Frontiers Media SA |
| Start Page | 668059 |
| ISSN | 2297-055X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34109226 |
| DOI | 10.3389/fcvm.2021.668059 |
| NAID | 120007053373 |
| Web of Science KeyUT | 000658156400001 |
| Related Url | isVersionOf https://doi.org/10.3389/fcvm.2021.668059 |
