result 326 件
| Author | Imai, Shigeo| |
|---|---|
| Published Date | 1993-02-27 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume105 |
| Issue | issue1-2 |
| Content Type | Journal Article |
| Author | Yamagata, Koichi| |
|---|---|
| Published Date | 1993-08 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume105 |
| Issue | issue7-8 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/ESR/13857 |
|---|---|
| Title Alternative | Drilling Research of a high-latiude coral reef in Mage Island, Stsunan Islands, Japan |
| FullText URL | ESR_12_49.pdf |
| Author | Kan, Hironobu| Nakashima, Yosuke| Ohashi, Tomoya| Hamanaka, Nozomu| Okamoto, Takehiro| Nakai, Tatsuo| Hori, Nobuyuki| |
| Abstract | Four drilling cores are observed from a high-latitude coral reef at the northwestern Mage Island (N30゜45' 40"). The thickness of the Holocene reef is around 2.5m in the reef edge and 4m in back reef. The Holocene thickness is relatively thin comparing to the modern reefs in the middle or the southern Ryukyu Islands. The reef structure Acropora facies, reworked coral rubble facies. This zonal structure conforms to the ecological coral-zonation corresponding to the wave-energy gradient. |
| Keywords | Holocene Coral Reef Sedimentary Structure Drilling Southwestem Japan |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2005-12-31 |
| Volume | volume12 |
| Issue | issue1 |
| Start Page | 49 |
| End Page | 58 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | 岡山大学地球科学研究報告編集委員会 |
| File Version | publisher |
| NAID | 120002310535 |
| Author | Kimura, Kazuhi| |
|---|---|
| Published Date | 1994-10 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume106 |
| Issue | issue9-10 |
| Content Type | Journal Article |
| Author | Miyahara, Nobuaki| |
|---|---|
| Published Date | 1994-08 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume106 |
| Issue | issue7-8 |
| Content Type | Journal Article |
| Author | Okamoto, Makoto| |
|---|---|
| Published Date | 1994-08 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume106 |
| Issue | issue7-8 |
| Content Type | Journal Article |
| Author | Okamoto, Makoto| |
|---|---|
| Published Date | 1994-08 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume106 |
| Issue | issue7-8 |
| Content Type | Journal Article |
| Author | Takai, Kenichi| Kunitomi, Mie| Ohta, Sachiko| Matsuoka, Junji| Kurose, Masao| Kojima, Kazushi| |
|---|---|
| Published Date | 1996-06-29 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume108 |
| Issue | issue3-6 |
| Content Type | Journal Article |
| Author | Ishibashi, Tadaaki| |
|---|---|
| Published Date | 1999-08-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume111 |
| Issue | issue3-8 |
| Content Type | Journal Article |
| Author | Araki, Hidetoshi| |
|---|---|
| Published Date | 1997-06-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume109 |
| Issue | issue3-6 |
| Content Type | Journal Article |
| Author | Murakami, Shinichirou| Matsuoka, Hiroaki| Fuyama, Yasuhiro| Taguchi, Takehito| Ohtsuka, Aiji| Murakami, Takuro| |
|---|---|
| Published Date | 2001-04-28 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume113 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Okamoto, Yoko| |
|---|---|
| Published Date | 2001-12-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume113 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Honda, Toru| |
|---|---|
| Published Date | 2005-05-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume115 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Okamoto, Kazuo| |
|---|---|
| Published Date | 2008-03-25 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Okamoto, Goro| Goto, Shintaro| Ueki, Keiji| |
|---|---|
| Published Date | 2008-02 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume97 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| Author | Okamoto, Goro| |
|---|---|
| Published Date | 2008-02 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume97 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| JaLCDOI | 10.18926/11921 |
|---|---|
| Title Alternative | Comparative studies of proliferating cell nuclear antigen and bromodeoxyuridine staining pattern in rat regenerating liver cells |
| FullText URL | 005_079_085.pdf |
| Author | Sakiyama, Junko| Mori, Shuji| Ichimura, Mituko| Tohge, Hiroko| Okamoto, Motoi| Endo, Hiroshi| |
| Abstract | 種々の条件下（10％緩衝ホルマリン・6時間、1％パラホルムアルデヒド・6時間、100％メタノール・4時間、70％エタノール・6時間、100％アセトン・2時間、カルノア液・4時間）で固定したラット再生肝組織に免疫組織染色を施し、Proliferating cell nuclear antigen （PCNA）の核内染色パターンについての検討を行った。その結果、100％メタノール及び70％エタノールで固定した場合には、明瞭な顆粒状の染色像が得られた。10％緩衝ホルマリン及び1％パラホルムアルデヒドの場合には、明瞭な顆粒状並びに弱いびまん性の染色像が得られた。S期に対する代表的なマーカーとして知られるBromodeoxyuridine （BrdU）の染色像との比較のもと、再生肝組織中のPCNA陽性細胞の数とBrdU陽性細胞の数を再生ピーク時の術後1日目で検討したところ、100％メタノール及び70％エタノールで固定した際の陽性細胞数が、最もBrdUの所見と一致した。しかし、10％緩衝ホルマリン、1％パラホルムアルデヒド、100％アセトン、カルノア液で固定した場合には、BrdUの所見と著しい解離が見られた。これらの知見は、PCNAを指標に細胞増殖を評価する上で、100％メタノール、70％エタノールでの固定が有用であることを示唆する。 |
| Keywords | PCNA BrdU 免疫組織染色 (immunohistochemical staining) 再生肝 (regenerating liver) |
| Publication Title | 岡山大学医療技術短期大学部紀要 |
| Published Date | 1995-01-31 |
| Volume | volume5 |
| Start Page | 79 |
| End Page | 85 |
| ISSN | 0917-4494 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313417 |
| JaLCDOI | 10.18926/11869 |
|---|---|
| FullText URL | 004_037_045.pdf |
| Author | Okamoto, Motoi| Mori, Shuji| Nita Nahoko| Noyori Maki| Hirano Humiko| |
| Abstract | 神経生物学的研究における基本的分析系の確立を目的として、シクロデキストリン（CD）を用いたラット大脳皮質神経細胞の初代培養を試みた。β-およびγ-CDは、無血清培地（ダルベッコ改変MEM/ハム培地）中で胎生16および18日目ラットの神経細胞を11日以上10％胎児ウシ血清を加えた培地中と同じ程度に生存させたが、α-CDには生存維持効果が無かった。β-CDはγ-CDより安定した生存維持効果を示したが、胎生21日目ラットの神経細胞を用いた場合は有意に生存率が低下し、新生児ラットでは生存維持効果が無かった。β-CDを用いた無血清培養では10％血清培地中と比べて神経突起の伸展が悪かったが、ときに顕著な突起伸展がみられ、これはCD分子に取り込まれた生理活性物質の作用と考えられた。また、β-CDを用いた無血清培養を利用してラット脳から精製したコンドロイチン硫酸プロテオグリカン（CSPG）の作用を検討し、CSPGがグルタミン酸による神経細胞死を防止すること、弱いながら培養神経細胞の生存を維持する作用をもつことを示した。以上の結果から、この無血清培養法は神経生物学的研究において有用な分析系となりうることを指摘した。 |
| Keywords | β-cyclodextrins γ-cyclodextrins serum-free culture cortical neuron chondroitin sulfate proteoglycan |
| Publication Title | 岡山大学医療技術短期大学部紀要 |
| Published Date | 1994-01-31 |
| Volume | volume4 |
| Start Page | 37 |
| End Page | 45 |
| ISSN | 0917-4494 |
| language | English |
| File Version | publisher |
| NAID | 120002313740 |
| JaLCDOI | 10.18926/11818 |
|---|---|
| Title Alternative | Alcoholic Liver Disease |
| FullText URL | 003_001_012.pdf |
| Author | Endo, Hiroshi| Nakata, Yasunari| Okamoto, Motoi| Mori, Shuji| Ohta, Takeo| |
| Abstract | Relationship between ethanol drinking and organs injury was reviewed and special emphasis was put on alcoholic liver disease. Consumption of alcoholic beverage expressed as ethanol per capita of adult in Japan increased 2.1 times in these 25 years and it is still increasing. Although the incidence of alcoholic liver disease in Japan also increased greatly during the above period, it seems likely that plateau level is coming because of genetically defined, unique type of alcohol metabolism in Japanese. Sex differences in susceptibility to alcohol were discussed. Among the six types of alcoholic liver disease, alcoholic liver fibrosis is relatively frequent in Japan. Mechanism of liver injury has been studied extensively. Alcohol itself is toxic but other factors such as dietary fat are also important. Biochemical and immunological markers of drinking were presented. As for the treatment, most patients especially in early stages of the disease well respond to alcohol withdrawal, but therapy of alcohol dependence in the background of the disease is very difficult requiring cooperative works of different kinds of specialists. |
| Keywords | alcohol liver epidemiology genetic factors alcohol dependence |
| Publication Title | 岡山大学医療技術短期大学部紀要 |
| Published Date | 1993-01-31 |
| Volume | volume3 |
| Start Page | 1 |
| End Page | 12 |
| ISSN | 0917-4494 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313726 |
| JaLCDOI | 10.18926/11783 |
|---|---|
| Title Alternative | The Neurophysiological Implications of an Atypical Slow Negative Potential in Short Interval CNV Paradigm |
| FullText URL | 001_091_097.pdf |
| Author | Okamoto, Motoi| Temino, Masato| Nakagawa, Naohisa| Mori, Hirokazu| |
| Abstract | We recorded a slow negative potential from Cz (10/20 method) in 49 healthy students (12 male, 37 female, mean age 19.1) by a short interstumulus interval CNV paradigm. The interstimulus interval was 2 or 3 seconds, the warning stimulus presented at random or regular interval at 0.2 Hz. An atypical negative variation with two separated negative peaks was recorded in 26.0-30.6% trials regardless of interstimulus interval or modality of warning stimulus presentation, while a typical CNV was recorded in 32.0-59.2% of trials. No apparent negative variation was recorded in 14.3-18.4% in 2 seconds interstimulus interval, and 28-38% in 3 seconds interstimulus interval, showing that 2 seconds interval is better to get stable CNV recording than 3 seconds interval. The first negative wave of the atypical negative variation was 692-799msec in duration, but frequently prolonged to 1000msec or more in 3 seconds interval. It usually had negative peak around 900-1100msec, but sometimes around 1500msec. This features are different from any reported negative components of CNV. The second negative wave began 800-1200msec before second stimulus, and had its peak just before second stimulus, showing common features with readiness potential. The appearance of CNV was unsatble in the students in which the atypical negative variation was recorded in regular, 2 seconds intersitimulus interval, and the amplitude of slow vertex response and pattern reversal visual evoked potential was lower in thses students than in the students in which a typical CNV was recorded more than 3 times in total 4 times of trials. These findings indicate that the atypical variation observed in this study is due to a lowered arousal level or cortical neuronal activity, rather than a separated appearance of different components of CNV. |
| Keywords | contingent negative variation atypical slow negative potential arousal level slow vertex response visual evoked potential |
| Publication Title | 岡山大学医療技術短期大学部紀要 |
| Published Date | 1991-03-25 |
| Volume | volume1 |
| Start Page | 91 |
| End Page | 97 |
| ISSN | 0917-4494 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313945 |
