Conditions

close

result 49234 件

JaLCDOI 10.18926/AMO/67198
FullText URL 78_3_237.pdf
Author Muraoka, Osamu| Imai, Norio| Kuraishi, Tatsuya| Imai, Makoto| Fukuhara, Takashi| Yoshimine, Toshifumi|
Abstract Fracture liaison services (FLS) have been introduced in Japan and several other countries to reduce medical complications and secondary fractures. We aimed to evaluate the effects of the implementation of an FLS approach on patient outcomes during hospitalization at our hospital and over a 2-year follow-up post-injury. This retrospective cohort study included patients ≥ 60 years admitted to our hospital for hip fragility fractures between October 1, 2016, and July 31, 2020. Patient groups were defined as those treated before (control group, n=238) and after (FLS group, n=196) establishment of the FLS protocol at our institution. The two groups were compared in terms of time to surgery, length of hospital stay, and the incidence of complications after admission, including secondary hip fracture and mortality rates. The follow-up period was 24 months. FLS focuses on early surgery within 48 h of injury and assessing osteoporosis treatment before injury to guide post-discharge anti-osteoporosis medication. FLS reduced the length of hospital stay (p<0.001) and the prevalence of complications after admission (p<0.001), particularly cardiovascular disease, and it increased adherence to anti-osteoporosis medication. These FLS effects resulted in lower secondary hip fracture and mortality rates at 12 and 24 months post-injury. FLS for fragility hip fractures can improve patient outcomes during hospitalization and over a 2-year follow-up period.
Keywords fracture liaison services complications after admission secondary hip fracture mortality
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-06
Volume volume78
Issue issue3
Publisher Okayama University Medical School
Start Page 237
End Page 243
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38902211
Web of Science KeyUT 001267351000004
JaLCDOI 10.18926/AMO/67197
FullText URL 78_3_227.pdf
Author Wada, Yudai| Ushio, Soichiro| Kitamura, Yoshihisa| Zamami, Yoshito| Sendo, Toshiaki|
Abstract Zolpidem, a non-benzodiazepine hypnotic, is primarily used to treat insomnia. In a previous study, pior treatment with non-benzodiazepine receptor agonists was associated with inflammation. The present study aimed to clarify the association between the effects of zolpidem and inflammation in mice treated with lipopolysaccharide (LPS), a known model of inflammation. We assessed the zolpidem-induced loss of righting reflex (LORR) duration 24 h after LPS treatment in mice. Additionally, the expressions of γ-aminobutyric acid (GABA)A receptor subunit and K+-Cl− cotransporter isoform 2 (KCC2) mRNA in the hippocampus and frontal cortex were examined in LPS-treated mice. Pretreatment with LPS was associated with significantly prolonged duration of zolpidem-induced LORR compared to control mice. This effect was significantly attenuated by administering bicuculline, a GABAA receptor antagonist, or flumazenil, a benzodiazepine receptor antagonist, in LPS-treated mice. Compared to controls, LPS-treated mice showed no significant change in the expression of GABAA receptor subunits in the hippocampus or frontal cortex. Bumetanide, an Na+-K+-2Cl− cotransporter isoform 1 blocker, attenuated the extended duration of zolpidem-induced LORR observed in LPS-treated mice. LPS significantly decreased Kcc2 mRNA expression in the hippocampus and the frontal cortex. These findings suggest that inflammation increases zolpidem-induced LORR, possibly through a reduction in KCC2 expression.
Keywords lipopolysaccharide zolpidem GABAA receptor K+-Cl− cotransporters
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-06
Volume volume78
Issue issue3
Publisher Okayama University Medical School
Start Page 227
End Page 235
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38902210
Web of Science KeyUT 001267351000003
JaLCDOI 10.18926/AMO/67196
FullText URL 78_3_215.pdf
Author Akagawa, Takuya| Fukui, Ryohei| Kida, Katsuhiro| Matsuura, Ryutaro| Shimada, Makoto| Kinoshita, Mitsuhiro| Akagawa, Yoko| Goto, Sachiko|
Abstract We propose a sitting position that achieves both high image quality and a reduced radiation dose in elbow joint imaging by area detector computed tomography (ADCT), and we compared it with the ‘superman’ and supine positions. The volumetric CT dose index (CTDIvol) for the sitting, superman, and supine positions were 2.7, 8.0, and 20.0 mGy and the dose length products (DLPs) were 43.4, 204.7, and 584.8 mGy • cm, respectively. In the task-based transfer function (TTF), the highest value was obtained for the sitting position in both bone and soft tissue images. The noise power spectrum (NPS) of bone images showed that the superman position had the lowest value up to approx. 1.1 cycles/mm or lower, whereas the sitting position had the lowest value when the NPS was greater than approx. 1.1 cycles/mm. The overall image quality in an observer study resulted in the following median Likert scores for Readers 1 and 2: 5.0 and 5.0 for the sitting position, 4.0 and 3.5 for the superman position, and 4.0 and 2.0 for the supine position. These results indicate that our proposed sitting position with ADCT of the elbow joint can provide superior image quality and allow lower radiation doses compared to the superman and supine positions.
Keywords area detector computed tomography elbow joint sitting position dose reduction image quality assessment
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-06
Volume volume78
Issue issue3
Publisher Okayama University Medical School
Start Page 215
End Page 225
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38902209
Web of Science KeyUT 001267351000002
JaLCDOI 10.18926/AMO/67195
FullText URL 78_3_205.pdf
Author Hagiya, Hideharu|
Abstract The global pandemic of COVID-19 has underscored the significance of establishing and sustaining a practical and efficient infection control system for the benefit and welfare of society. Infectious disease (ID) specialists are expected to take on leadership roles in enhancing organizational infrastructures for infection prevention and control (IPC) at the hospital, community, and national levels. However, due to an absolute shortage and an uneven distribution, many core hospitals currently lack the ID specialists. Given the escalating global risk of emerging and re-emerging infectious diseases as well as antimicrobial resistance pathogens, the education and training of ID specialists constitutes an imperative concern. As demonstrated by historical changes in the healthcare reimbursement system, the establishment and enhancement of IPC measures is pivotal to ensuring medical safety. The existing structure of academic society-driven certification and training initiatives for ID specialists, contingent upon the discretionary decisions of individual physicians, possesses both quantitative and qualitative shortcomings. In this article, I first address the present situations and challenges related to ID specialists and then introduce my idea of securing ID specialists based on the new concepts and platforms; (i) ID Specialists as National Credentials, (ii) Establishment of the Department of Infectious Diseases in Medical and Graduate Schools, (iii) Endowed ID Educative Courses Funded by Local Government and Pharmaceutical Companies, and (iv) Recruitment of Young Physicians Engaged in Healthcare Services in Remote Areas. As clarified by the COVID-19 pandemic, ID specialists play a crucial role in safeguarding public health. Hopefully, this article will advance the discussion and organizational reform for the education and training of ID specialists.
Keywords antimicrobial resistance emerging infectious diseases infection prevention and control medical education silent pandemic
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2024-06
Volume volume78
Issue issue3
Publisher Okayama University Medical School
Start Page 205
End Page 213
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38902208
Web of Science KeyUT 001267351000001
FullText URL fulltext.pdf
Author Swe, Hnin‐Wint‐Wint| Fujisawa, Masayoshi| Ohara, Toshiaki| Komatsubara, Yu| Yoshimura, Teizo| Shien, Tadahiko| Matsukawa, Akihiro|
Keywords angiogenesis blood vessels breast cancer CD31 antigen immunohistochemistry microvessel density survival analysis
Published Date 2024-05-31
Publication Title Pathology International
Volume volume74
Issue issue7
Publisher Wiley
Start Page 394
End Page 407
ISSN 1320-5463
NCID AA10984364
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version publisher
PubMed ID 38818885
DOI 10.1111/pin.13442
Web of Science KeyUT 001235649700001
Related Url isVersionOf https://doi.org/10.1111/pin.13442
FullText URL fulltext.pdf
Author Ngo, An Thuy| Mori, Yasushi| Bui, Long Thanh|
Keywords Soil amendments water -saving polymers soil moisture improvement mean weight diameter irrigation water
Published Date 2024-08
Publication Title Environmental Technology & Innovation
Volume volume35
Publisher Elsevier
Start Page 103650
ISSN 2352-1864
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version publisher
DOI 10.1016/j.eti.2024.103650
Web of Science KeyUT 001238871900001
Related Url isVersionOf https://doi.org/10.1016/j.eti.2024.103650
FullText URL fulltext.pdf
Author Takamura, Hiroyoshi| Sugitani, Yuki| Morishita, Ryohei| Yorisue, Takefumi| Kadota, Isao|
Published Date 2024
Publication Title Organic & Biomolecular Chemistry
Volume volume22
Issue issue28
Publisher Royal Society of Chemistry (RSC)
Start Page 5739
End Page 5747
ISSN 1477-0520
NCID AA1168650X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Royal Society of Chemistry 2024
File Version publisher
PubMed ID 38828517
DOI 10.1039/d4ob00698d
Web of Science KeyUT 001237473000001
Related Url isVersionOf https://doi.org/10.1039/d4ob00698d
FullText URL fulltext.pdf
Author Ueno, Asami| Onishi, Yasuhiro| Mise, Koki| Yamaguchi, Satoshi| Kanno, Ayaka| Nojima, Ichiro| Higuchi, Chigusa| Uchida, Haruhito A.| Shikata, Kenichi| Miyamoto, Satoshi| Nakatsuka, Atsuko| Eguchi, Jun| Hida, Kazuyuki| Katayama, Akihiro| Watanabe, Mayu| Nakato, Tatsuaki| Tone, Atsuhito| Teshigawara, Sanae| Matsuoka, Takashi| Kamei, Shinji| Murakami, Kazutoshi| Shimizu, Ikki| Miyashita, Katsuhito| Ando, Shinichiro| Nunoue, Tomokazu| Wada, Jun|
Published Date 2024-05
Publication Title BMJ Open Diabetes Research and Care
Volume volume12
Issue issue3
Publisher BMJ Publishing Group
Start Page e004237
ISSN 2052-4897
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Author(s) (or their employer(s)) 2024.
File Version publisher
PubMed ID 38816205
DOI 10.1136/bmjdrc-2024-004237
Web of Science KeyUT 001236385500001
Related Url isVersionOf https://doi.org/10.1136/bmjdrc-2024-004237
FullText URL fulltext.pdf
Author Vo, Quan Duy| Saito, Yukihiro| Ida, Toshihiro| Nakamura, Kazufumi| Yuasa, Shinsuke|
Published Date 2024-05-21
Publication Title PLoS ONE
Volume volume19
Issue issue5
Publisher Public Library of Science
Start Page e0302537
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Vo et al.
File Version publisher
PubMed ID 38771829
DOI 10.1371/journal.pone.0302537
Web of Science KeyUT 001228816000059
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0302537
FullText URL fulltext.pdf
Author Mao, Zhiyuan| Li, Xingyue| Li, Zhenhua| Shen, Liangliang| Li, Xiaoyi| Yang, Yanyan| Wang, Wenda| Kuang, Tingyun| Shen, Jian-Ren| Han, Guangye|
Note The version of record of this article, first published in Nature Communications, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41467-024-48878-x|
Published Date 2024-05-28
Publication Title Nature Communications
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 4535
ISSN 2041-1723
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38806516
DOI 10.1038/s41467-024-48878-x
Web of Science KeyUT 001234660500031
Related Url isVersionOf https://doi.org/10.1038/s41467-024-48878-x
FullText URL fulltext.pdf
Author Shibata, Masashi| Otsuka, Yuki| Hagiya, Hideharu| Koyama, Toshihiro| Kashiwagi, Hideyuki| Otsuka, Fumio|
Published Date 2024-02-28
Publication Title PLoS ONE
Volume volume19
Issue issue2
Publisher Public Library of Science
Start Page e0299700
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Shibata et al.
File Version publisher
PubMed ID 38416759
DOI 10.1371/journal.pone.0299700
Web of Science KeyUT 001181689500043
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0299700
FullText URL fulltext.pdf
Author Zhang, Nan| An, Weichao| Yu, Yinghua| Wu, Jinglong| Yang, Jiajia|
Keywords response inhibition ratio go/no-go task ERP NoGo-P3 component
Published Date 2024-04-24
Publication Title Brain Sciences
Volume volume14
Issue issue5
Publisher MDPI
Start Page 414
ISSN 2076-3425
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38790393
DOI 10.3390/brainsci14050414
Web of Science KeyUT 001232265800001
Related Url isVersionOf https://doi.org/10.3390/brainsci14050414
FullText URL fulltext.pdf
Author Yamamoto, Koichiro| Oguni, Kohei| Otsuka, Fumio|
Keywords adrenal cyst adrenal incidentaloma adrenal tumor hypertension
Published Date 2024-05-24
Publication Title Clinical Case Reports
Volume volume12
Issue issue6
Publisher Wiley
Start Page e8914
ISSN 2050-0904
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version publisher
PubMed ID 38799545
DOI 10.1002/ccr3.8914
Web of Science KeyUT 001230589300001
Related Url isVersionOf https://doi.org/10.1002/ccr3.8914
FullText URL fulltext.pdf
Author Sakurada, Takato| Chikada, Yuta| Miyahara, Ryo| Taniguchi, Yosuke|
Keywords 8-oxo-2 '-deoxyguanosine single nucleotide elongation reaction artificial nucleoside triphosphate 2 '-deoxycytidine derivatives
Published Date 2024-05-11
Publication Title Molecules
Volume volume29
Issue issue10
Publisher MDPI
Start Page 2270
ISSN 1420-3049
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38792131
DOI 10.3390/molecules29102270
Web of Science KeyUT 001231259100001
Related Url isVersionOf https://doi.org/10.3390/molecules29102270
FullText URL fulltext.pdf
Author Sue, Masahiko| Takeuchi, Yasuto| Hirata, Shoichiro| Takaki, Akinobu| Otsuka, Motoyuki|
Keywords immune-related adverse events serum albumin real-world practice
Published Date 2024-05-09
Publication Title Cancers
Volume volume16
Issue issue10
Publisher MDPI
Start Page 1811
ISSN 2072-6694
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38791890
DOI 10.3390/cancers16101811
Web of Science KeyUT 001233134000001
Related Url isVersionOf https://doi.org/10.3390/cancers16101811
FullText URL fulltext.pdf
Author Mu, Xindi| Ono, Mitsuaki| Nguyen, Ha Thi Thu| Wang, Ziyi| Zhao, Kun| Komori, Taishi| Yonezawa, Tomoko| Kuboki, Takuo| Oohashi, Toshitaka|
Keywords cell differentiation epithelia growth factor(s) bioinformatics extracellular matrix (ECM) mucocutaneous disorders
Published Date 2024-05-09
Publication Title Cells
Volume volume13
Issue issue10
Publisher MDPI
Start Page 807
ISSN 2073-4409
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38786031
DOI 10.3390/cells13100807
Web of Science KeyUT 001232270600001
Related Url isVersionOf https://doi.org/10.3390/cells13100807
FullText URL fulltext.pdf
Author Moriwake, Kazuya| Noma, Kazuhiro| Kawasaki, Kento| Matsumoto, Tasuku| Hashimoto, Masashi| Kato, Takuya| Maeda, Naoaki| Tanabe, Shunsuke| Shirakawa, Yasuhiro| Fujiwara, Toshiyoshi|
Keywords Reconstruction with the free jejunum flap Subtotal esophagectomy After pancreatoduodenectomy
Note The version of record of this article, first published in Surgical Case Reports, is available online at Publisher’s website: http://dx.doi.org/10.1186/s40792-024-01919-5|
Published Date 2024-05-22
Publication Title Surgical Case Reports
Volume volume10
Issue issue1
Publisher Springer
Start Page 128
ISSN 2198-7793
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38775882
DOI 10.1186/s40792-024-01919-5
Web of Science KeyUT 001229350000001
Related Url isVersionOf https://doi.org/10.1186/s40792-024-01919-5
FullText URL fulltext.pdf
Author Miyoshi, Shin-Ichi| Kurata, Megumi| Hirose, Riho| Yoshikawa, Masaya| Liang, Yong| Yamagishi, Yosuke| Mizuno, Tamaki|
Keywords Vibrio cholerae Vibrio vulnificus genotype LAMP water temperature
Published Date 2024-04-27
Publication Title Microorganisms
Volume volume12
Issue issue5
Publisher MDPI
Start Page 877
ISSN 2076-2607
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38792707
DOI 10.3390/microorganisms12050877
Web of Science KeyUT 001231571500001
Related Url isVersionOf https://doi.org/10.3390/microorganisms12050877
FullText URL fulltext.pdf
Author Maruyama, Takayuki| Ekuni, Daisuke| Yokoi, Aya| Nagasaki, Junichiro| Sawada, Nanami| Morita, Manabu|
Keywords halitosis antimicrobial photodynamic therapy prevention randomized clinical trial
Published Date 2024-05-09
Publication Title Healthcare
Volume volume12
Issue issue10
Publisher MDPI
Start Page 980
ISSN 2227-9032
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38786391
DOI 10.3390/healthcare12100980
Web of Science KeyUT 001232995300001
Related Url isVersionOf https://doi.org/10.3390/healthcare12100980
FullText URL fulltext.pdf
Author Kunisada, Toshiyuki| Nakata, Eiji| Fujiwara, Tomohiro| Hata, Toshiaki| Sato, Kohei| Katayama, Haruyoshi| Kondo, Ayana| Ozaki, Toshifumi|
Keywords hydroxyapatite bone tumor orthopedic surgery unidirectional porous hydroxyapatite bone graft
Published Date 2024-05-15
Publication Title Biomimetics
Volume volume9
Issue issue5
Publisher MDPI
Start Page 294
ISSN 2313-7673
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38786504
DOI 10.3390/biomimetics9050294
Web of Science KeyUT 001232206900001
Related Url isVersionOf https://doi.org/10.3390/biomimetics9050294