result 11275 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Taniguchi, Fumitaka| Nyuya, Akihiro| Toshima, Toshiaki| Yasui, Kazuya| Mori, Yoshiko| Okawaki, Makoto| Kishimoto, Hiroyuki| Umeda, Yuzo| Fujiwara, Toshiyoshi| Tanioka, Hiroaki| Yamaguchi, Yoshiyuki| Goel, Ajay| Nagasaka, Takeshi| |
| Keywords | Acquired mutations BRAF colorectal cancer liquid biopsy PCR-rSSO RAS |
| Publication Title | Future Science OA |
| Publisher | Future Science Ltd. |
| Start Page | FSO757 |
| ISSN | 2056-5623 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Authors |
| File Version | publisher |
| DOI | 10.2144/fsoa-2021-0059 |
| Web of Science KeyUT | 000715287900001 |
| Related Url | isVersionOf https://doi.org/10.2144/fsoa-2021-0059 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Imran, Shahin| Tsuchiya, Yoshiyuki| Tran, Sen Thi Huong| Katsuhara, Maki| |
| Keywords | Na+ transport rice OsHKT1 3 mRNA variants TEVC |
| Published Date | 2021-09-24 |
| Publication Title | Plants-Basel |
| Volume | volume10 |
| Issue | issue10 |
| Publisher | MDPI |
| Start Page | 2006 |
| ISSN | 2223-7747 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34685816 |
| DOI | 10.3390/plants10102006 |
| Web of Science KeyUT | 000712812800001 |
| Related Url | isVersionOf https://doi.org/10.3390/plants10102006 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Satouchi, Miyako| Nosaki, Kaname| Takahashi, Toshiaki| Nakagawa, Kazuhiko| Aoe, Keisuke| Kurata, Takayasu| Sekine, Akimasa| Horiike, Atsushi| Fukuhara, Tatsuro| Sugawara, Shunichi| Umemura, Shigeki| Saka, Hideo| Okamoto, Isamu| Yamamoto, Nobuyuki| Sakai, Hiroshi| Kishi, Kazuma| Katakami, Nobuyuki| Horinouchi, Hidehito| Hida, Toyoaki| Okamoto, Hiroaki| Atagi, Shinji| Ohira, Tatsuo| Han, Shi Rong| Noguchi, Kazuo| Ebiana, Victoria| Hotta, Katsuyuki| |
| Keywords | Japan non-small-cell lung carcinoma PD-L1 protein pembrolizumab treatment outcome |
| Published Date | 2021-09-20 |
| Publication Title | Cancer Science |
| Publisher | Wiley |
| ISSN | 1347-9032 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 34543477 |
| DOI | 10.1111/cas.15144 |
| Web of Science KeyUT | 000714623800001 |
| Related Url | isVersionOf https://doi.org/10.1111/cas.15144 |
| FullText URL | fulltext20211109-5.pdf |
|---|---|
| Author | Gotoh, Kazuyoshi| Mayura, I. Putu Bayu| Enomoto, Yusaku| Iio, Koji| Matsushita, Osamu| Otsuka, Fumio| Hagiya, Hideharu| |
| Keywords | Antimicrobial Resistance Daptomycin resistance Corynebacterium striatum Insertion sequence pgsA2 gene |
| Note | This is an Accepted Manuscript of an article published by Springer. This fulltext is available in Oct. 2022.| |
| Published Date | 2021-10-21 |
| Publication Title | European Journal of Clinical Microbiology & Infectious Diseases |
| Volume | volume41 |
| Issue | issue2 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 331 |
| End Page | 333 |
| ISSN | 0934-9723 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature |
| File Version | author |
| PubMed ID | 34671843 |
| DOI | 10.1007/s10096-021-04369-1 |
| Web of Science KeyUT | 000709253000001 |
| Related Url | isVersionOf https://doi.org/10.1007/s10096-021-04369-1 |
| FullText URL | fulltext20211109-4.pdf |
|---|---|
| Author | Arimura, Yuki| Minato, Yusuke| Wada, Takayuki| Nakayama, Masaaki| Ryumon, Ayako| Hirata, Nao| Nakajima, Chie| Suzuki, Yasuhiko| Ato, Manabu| Kobayashi, Kazuo| Ohara, Naoko| Iida, Seiji| Ohara, Naoya| |
| Keywords | thymidylate synthase ThyX Mycobacterium BCG |
| Note | This is the peer reviewed version of the following article: [Arimura, Y, Minato, Y, Wada, T, Nakayama, M, Ryumon, A, Hirata, N, et al. Attempt of thyX gene silencing and construction of a thyX deleted clone in a Mycobacterium bovis BCG. Microbiol Immunol. 2021; 1– 5. https://doi.org/10.1111/1348-0421.12944], which has been published in final form at [https://doi.org/10.1111/1348-0421.12944]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| Published Date | 2021-10-21 |
| Publication Title | Microbiology and Immunology |
| Volume | volume66 |
| Issue | issue1 |
| Publisher | Wiley |
| Start Page | 10 |
| End Page | 14 |
| ISSN | 0385-5600 |
| NCID | AA00738350 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Societies and John Wiley & Sons Australia, Ltd |
| File Version | author |
| PubMed ID | 34546594 |
| DOI | 10.1111/1348-0421.12944 |
| Web of Science KeyUT | 000709482200001 |
| Related Url | isVersionOf https://doi.org/10.1111/1348-0421.12944 |
| FullText URL | fulltext20211109-2.pdf Figs20211109-2.pdf |
|---|---|
| Author | Shiraishi, Yuri| Shiozaki, Tomoya| Asakura, Mami| Ide, Toru| Hayakawa, Tohru| |
| Keywords | Bacillus thuringiensis Cry4Aa toxin Culex pipiens mosquito larvae electrophysiologic analysis of channel-pores |
| Note | This is an Accepted Manuscript of an article published by Springer. This fulltext is available in Oct. 2022.| |
| Published Date | 2021-10-23 |
| Publication Title | Applied Entomology and Zoology |
| Volume | volume57 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 63 |
| End Page | 70 |
| ISSN | 0003-6862 |
| NCID | AA00543238 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Springer Nature Switzerland AG. |
| File Version | author |
| DOI | 10.1007/s13355-021-00762-6 |
| Web of Science KeyUT | 000710605800001 |
| Related Url | isVersionOf https://doi.org/10.1007/s13355-021-00762-6 |
| FullText URL | fulltext20211109-1.pdf |
|---|---|
| Author | Tokumasu, Kazuki| Ochi, Kanako| Otsuka, Fumio| |
| Note | This article has been accepted for publication in BMJ Case Reports, 2021 following peer review, and the Version of Record can be accessed online at https://doi.org/10.1136/bcr-2021-244861| This is an Accepted Manuscript of an article published by BMJ| |
| Published Date | 2021-10 |
| Publication Title | BMJ Case Reports |
| Volume | volume14 |
| Issue | issue10 |
| Publisher | BMJ |
| Start Page | e244861 |
| ISSN | 1757-790X |
| NCID | AA12533286 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | © BMJ Publishing Group Ltd ( for assignments of BMJ Case Reports) |
| File Version | author |
| PubMed ID | 34686480 |
| DOI | 10.1136/bcr-2021-244861 |
| Web of Science KeyUT | 000711054600001 |
| Related Url | isVersionOf https://doi.org/10.1136/bcr-2021-244861 |
| FullText URL | fulltext20211105-2.pdf Figure20211105-2.pdf Supporting_information20211105-2.pdf |
|---|---|
| Author | Habuer| Hamaguchi, Daisuke| Zhou, Yingjun| Fujimori, Takashi| Takaoka, Masaki| |
| Keywords | Excess mercury Long-term strategy Scenario analysis China Asia |
| Note | This is an Accepted Manuscript of an article published by Academic Consociation of Environmental Safety and Waste Management,Japan.| |
| Published Date | 2019-09-10 |
| Publication Title | Journal of Environment and Safety |
| Volume | volume10 |
| Issue | issue2 |
| Publisher | Academic Consociation of Environmental Safety and Waste Management, Japan |
| Start Page | 143 |
| End Page | 151 |
| ISSN | 1884-4375 |
| NCID | AA12480623 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 Academic Consociation of Environmental Safety and Waste Management,Japan |
| File Version | author |
| DOI | 10.11162/daikankyo.E19RP0303 |
| NAID | 130007705328 |
| Related Url | isVersionOf https://doi.org/10.11162/daikankyo.E19RP0303 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sumi, Tomonari| Harada, Kouji| |
| Published Date | 2021-10-22 |
| Publication Title | Communications Chemistry |
| Volume | volume4 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 149 |
| ISSN | 2399-3669 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021 |
| File Version | publisher |
| DOI | 10.1038/s42004-021-00585-0 |
| Web of Science KeyUT | 000710351300002 |
| Related Url | isVersionOf https://doi.org/10.1038/s42004-021-00585-0 |
| Title Alternative | Biophysical and Biochemical Research of Animal Rhodopsins |
|---|---|
| FullText URL | fulltext20211102-2.pdf |
| Author | Kojima, Keiichi| |
| Keywords | rhodopsin opsin retinal G protein coupled receptor vision |
| Published Date | 2021-10-1 |
| Publication Title | YAKUGAKU ZASSHI |
| Volume | volume141 |
| Issue | issue10 |
| Publisher | Pharmaceutical Society of Japan |
| Start Page | 1155 |
| End Page | 1160 |
| ISSN | 0031-6903 |
| NCID | AN00284903 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Pharmaceutical Society of Japan |
| File Version | publisher |
| PubMed ID | 34602512 |
| DOI | 10.1248/yakushi.21-00144 |
| Web of Science KeyUT | 000708444600004 |
| Related Url | isVersionOf https://doi.org/10.1248/yakushi.21-00144 |
| FullText URL | fulltext20211102-1.pdf |
|---|---|
| Author | Das, Subha| Alam, Md Mahfuz| Zhang, Rui| Hisano, Sakae| Suzuki, Nobuhiro| |
| Note | This is an Accepted Manuscript of an article published by American Society for Microbiology.| |
| Published Date | 2021-8-10 |
| Publication Title | Journal of Virology |
| Volume | volume95 |
| Issue | issue17 |
| Publisher | American Society for Microbiology |
| Start Page | e00467-21 |
| ISSN | 0022-538X |
| NCID | AA00708779 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 American Society for Microbiology. |
| File Version | author |
| PubMed ID | 34106772 |
| DOI | 10.1128/jvi.00467-21 |
| Web of Science KeyUT | 000708640500015 |
| Related Url | isVersionOf https://doi.org/10.1128/jvi.00467-21 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Inoguchi, Kyosuke| Hongo, Takashi| Naito, Hiromichi| Nakao, Atsunori| |
| Keywords | sepsis pelvic abscess conservative treatment neurogenic bladder bladder rupture |
| Published Date | 2021-10-19 |
| Publication Title | Cureus |
| Volume | volume13 |
| Issue | issue10 |
| Publisher | CUREUS INC |
| Start Page | e18913 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Inoguchi et al. |
| File Version | publisher |
| DOI | 10.7759/cureus.18913 |
| Web of Science KeyUT | 000709915500003 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.18913 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sun, Jingkai| Lin, Wenfeng| Li, Chaoming| Ueki, Hideo| Xue, Ruizhi| Sadahira, Takuya| Hu, Hao| Wada, Koichiro| Li, Na| Liu, Chunxiao| Araki, Motoo| Xu, Abai| Huang, Peng| |
| Keywords | Posaconazole cell cycle autophagy rhabdomyosarcoma hedgehog proteins |
| Published Date | 2021-09-30 |
| Publication Title | American Journal of Cancer Research |
| Volume | volume11 |
| Issue | issue9 |
| Publisher | e-Century Publishing Corporation |
| Start Page | 4528 |
| End Page | 4540 |
| ISSN | 2156-6976 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | AJCR (c)2021 e-Century Publishing Corp. |
| File Version | publisher |
| PubMed ID | 34659903 |
| Web of Science KeyUT | 000707716300029 |
| FullText URL | fulltext.pdf Corrigendum.pdf |
|---|---|
| Author | Wang, Chen| Maeda, Masakazu| Chen, Jian| Wang, Mengxue| Naruse, Keiji| Takahashi, Ken| |
| Keywords | TRPM4 Cardiomyocyte H9c2 CRISPR/Cas9 Confocal microscopy DNA sequencing Flow cytometry Western blotting |
| Published Date | 2021 |
| Publication Title | MethodsX |
| Volume | volume8 |
| Publisher | ELSEVIER |
| Start Page | 101404 |
| ISSN | 2215-0161 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 34430300 |
| DOI | 10.1016/j.mex.2021.101404 |
| Web of Science KeyUT | 000707187100026 |
| Related Url | isVersionOf https://doi.org/10.1016/j.mex.2021.101404 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ezenwa, Innocent C.| Yoshino, Takashi| |
| Keywords | electrical resistivity thermal conductivity electrons and phonons interactions high pressure and temperature constant resistivity melting curve |
| Published Date | 2021-09-22 |
| Publication Title | Materials |
| Volume | volume14 |
| Issue | issue19 |
| Publisher | MDPI |
| Start Page | 5476 |
| ISSN | 1996-1944 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34639875 |
| DOI | 10.3390/ma14195476 |
| Web of Science KeyUT | 000707452700001 |
| Related Url | isVersionOf https://doi.org/10.3390/ma14195476 |
| JaLCDOI | 10.18926/AMO/62820 |
|---|---|
| FullText URL | 75_6_763.pdf |
| Author | Iwata, Takehiro| Sadahira, Takuya| Maruyama, Yuki| Sekito, Takanori| Yoshinaga, Kasumi| Watari, Shogo| Nagao, Kentaro| Kawada, Tatsushi| Tominaga, Yusuke| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Araki, Motoo| Ishii, Ayano| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| Wada, Koichiro| |
| Abstract | The aim of this ongoing trial is to evaluate the clinical efficacy and safety of sitafloxacin (STFX) 200 mg once daily (QD) for 7 days in patients with refractory genitourinary tract infections, which include recurrent or complicated cystitis, complicated pyelonephritis, bacterial prostatitis, and epididymitis. The primary endpoint is the microbiological efficacy at 5-9 days after the last administration of STFX. Recruitment began in February 2021, and the target total sample size is 92 participants. |
| Keywords | genitourinary tract infections fluoroquinolone resistance extended-spectrum beta-lactamase |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 763 |
| End Page | 766 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955548 |
| Web of Science KeyUT | 000735319800006 |
| NAID | 120007180272 |
| JaLCDOI | 10.18926/AMO/62819 |
|---|---|
| FullText URL | 75_6_759.pdf |
| Author | Shimizu, Dai| Yamamoto, Hiromasa| Shien, Kazuhiko| Taniguchi, Kohei| Miyoshi, Kentaroh| Namba, Kei| Mesaki, Kumi| Sugimoto, Seiichiro| Soh, Junichi| Yamane, Masaomi| Toyooka, Shinichi| |
| Abstract | Pulmonary enteric adenocarcinoma (PEAC) is a rare subtype of lung cancer that should be differentiated from colorectal cancer metastasis. Little is known about its genetic background. An 84-year-old male with adenocarcinoma of the lung underwent left upper lobectomy. The histology of the surgical specimen was suggestive of PEAC. Gastrointestinal and colorectal fiberscopy revealed no evidence of colorectal cancer. Next-generation sequencing of the tumor identified a G469V substitution in serine/threonine-protein kinase B-raf (BRAF). Based on the higher prevalence of the G469 substitution in BRAF-mutant lung adenocarcinoma than in BRAFmutant colorectal cancer, the tumor likely originated from the lung. Identification of mutational genotype may be of some help in distinguishing PEAC from the lung metastasis of colorectal cancer. |
| Keywords | non-small cell lung cancer somatic mutations pulmonary adenocarcinoma with enteric differentiation non-V600E BRAF mutation next-generation sequencing |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 759 |
| End Page | 762 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955547 |
| Web of Science KeyUT | 000735319800005 |
| NAID | 120007180273 |
| JaLCDOI | 10.18926/AMO/62816 |
|---|---|
| FullText URL | 75_6_745.pdf |
| Author | Hayata, Kei| Mishima, Sakurako| Ohira, Akiko| Tani, Kazumasa| Maki, Jota| Eto, Eriko| Ogawa, Chikako| Masuyama, Hisashi| |
| Abstract | NIPT is non-definitive testing to estimate the possibility that fetuses have trisomy 21, trisomy 18, or trisomy 13. However, in NIPT-positive and indeterminate cases, rare chromosomal disease may become apparent, requiring advanced genetic considerations and counseling skills. We experienced two such cases, a trisomy 21 mosaicism case triggered by NIPT-positive status and 18q deletion syndrome triggered by NIPT-indeterminate status. These cases have two clinical implications for NIPT. First, it was revealed that trisomy mosaicism might be found in NIPT-positive cases that have lower Z-Scores than those inferred from the fraction of fetal cfDNA in the case of standard trisomy. Second, it is possible that microdeletion syndrome could be the reason for an indeterminate NIPT result. Today’s genetic counseling requires more expertise in ethics and communication as well as genetic science because NIPT can lead to totally unexpected results. |
| Keywords | NIPT massively parallel sequencing trisomy 21 mosaicism 18q-deletion syndrome genetic counseling |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 745 |
| End Page | 750 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955544 |
| Web of Science KeyUT | 000735319800002 |
| NAID | 120007180276 |
| JaLCDOI | 10.18926/AMO/62815 |
|---|---|
| FullText URL | 75_6_741.pdf |
| Author | Morita, Tetsuro| Shiode, Yusuke| Kimura, Shuhei| Hosokawa, Mio| Doi, Shinichiro| Takahashi, Kosuke| Matoba, Ryo| Kanzaki, Yuki| Tabata, Masahiro| Morizane, Yuki| |
| Abstract | A 65-year-old man presented with a 1-week history of left eye distortion. An elevated choroidal lesion covering 6 disc diameters was found in the posterior retina of the left eye. Systemic examination revealed sublingual gland carcinoma and multiple lung metastases, and the diagnosis was choroidal metastasis from sublingual gland carcinoma. Following chemotherapy and radiation therapy, the choroidal lesion shrunk and the patient’s visual acuity improved. The patient died 23 months after his first visit. To the best of our knowledge, this is the first reported case of choroidal metastasis from sublingual gland carcinoma. |
| Keywords | adenoid cystic carcinoma choroidal metastasis sublingual gland |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 741 |
| End Page | 744 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955543 |
| Web of Science KeyUT | 000735319800001 |
| NAID | 120007180277 |
| JaLCDOI | 10.18926/AMO/62813 |
|---|---|
| FullText URL | 75_6_725.pdf |
| Author | Matsumoto, Hiroshi| Kimata, Yoshihiro| Ota, Tomoyuki| Sugiyama, Narushi| Onoda, Satoshi| Makino, Takuma| Takeda, Seiko| Mizukawa, Nobuyoshi| |
| Abstract | The long-term changes in tissues implanted in the oral cavity and pharynx after head and neck reconstruction have not been fully evaluated. This study aimed to clarify the morphological changes, long-term durability, and potential for secondary carcinogenesis in such tissues. In our single-center study, the rough morphological changes in 54 cases of intraoral and pharyngeal skin and mucosal flaps were evaluated more than 10 years after flap transfer. In addition, the literature on the development of second carcinomas from skin flaps was reviewed. The mean follow-up period for transferred flaps was 148 months. The reconstruction areas and the probability of morphological changes were significantly correlated (p=0.006), especially in cases with tongue, lower gingiva, and buccal mucosal reconstruction. Free jejunal flap surfaces were well maintained, whereas tubed skin flaps showed severe morphological changes in cases with pharyngeal reconstruction. None of the flaps in our series developed second primary carcinomas. Skin flaps generally had good durability for > 10 years in intraoral environments, while mucosal flaps had better durability for pharyngeal reconstruction. Second squamous carcinomas arising from skin flaps are extremely rare; however, surgeons should take this possibility into consideration and conduct meticulous and long-term follow-up. |
| Keywords | skin flap mucosal flap oral reconstruction morphological change second primary carcinoma |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-12 |
| Volume | volume75 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 725 |
| End Page | 734 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34955541 |
| NAID | 120007180279 |
