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ID 31601
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Author
Gu, Yin-chun
Okada, Shin-ichi
Ohomori, Masakazu
Kitajiri, Shin-ichiro
Namba, Masayoshi
Abstract

<P>Effects of methanol on colony-formation of human hepatoma cells were investigated. Among five human hepatoma cell lines (Hep G2, HLE, HuH-6, HuH-7, and PLC/PRF/5), only HLE cells showed enhanced colony formation due to methanol. The effective concentrations of methanol were around 1%. The enhancement occurred in a greater degree when the cells were seeded in the culture medium containing methanol than when methanol was added 24h after the cells were seeded. Methanol itself, however, did not enhance the cell proliferation.

Keywords
methanol
hepatoma
colony-formation
in vitro
Amo Type
Article
Publication Title
Acta Medica Okayama
Published Date
1993-02
Volume
volume47
Issue
issue1
Publisher
Okayama University Medical School
Start Page
35
End Page
38
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT