result 1261 件
| JaLCDOI | 10.18926/AMO/59959 |
|---|---|
| FullText URL | 74_3_251.pdf |
| Author | Murakami, Takashi| Tokuda, Takanori| Nishimura, Shinsuke| Fujii, Hiromichi| Takahashi, Yosuke| Yamane, Kokoro| Inoue, Kazushige| Yamada, Koichi| Kakeya, Hiroshi| Shibata, Toshihiko| |
| Abstract | A 62-year-old Japanese male presented with graft infection by Staphylococcus schleiferi 50 days after debranching of the left subclavian artery and frozen elephant trunk repair for the entry closure of a Stanford type B aortic dissection. The graft was removed, and the patient was successfully treated using in situ reconstruction of the arch with omental flap coverage, removal of the debranching graft, autologous iliac artery grafting, and longterm antibiotics. Domino reconstruction of the infected debranching graft using autologous external iliac artery and a Dacron graft can thus be a good option in similar cases. |
| Keywords | autologous iliac artery graft Staphylococcus schleiferi graft infection domino reconstruction Dacron graft |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-06 |
| Volume | volume74 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 251 |
| End Page | 255 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32577024 |
| Web of Science KeyUT | 000543363400009 |
| NAID | 120006862800 |
| JaLCDOI | 10.18926/AMO/59958 |
|---|---|
| FullText URL | 74_3_245.pdf |
| Author | Yamamoto, Shumpei| Takayama, Hiroshi| Shimodate, Yuichi| Takezawa, Rio| Nishimura, Naoyuki| Doi, Akira| Mouri, Hirokazu| Matsueda, Kazuhiro| Mizuno, Motowo| Okada, Hiroyuki| |
| Abstract | Antithrombotic therapy is a major risk factor for delayed bleeding after endoscopic submucosal dissection (ESD) for gastric neoplasia. A potassium-competitive acid blocker, vonoprazan, is expected to prevent delayed bleeding better than conventional proton pomp inhibitors (PPIs), but the evidence is controversial. We sought to clarify the efficacy of vonoprazan for prevention of delayed bleeding after gastric ESD in patients under antithrombotic therapy. We prospectively registered 50 patients who underwent gastric ESD while receiving antithrombotic therapy and vonoprazan in our institution between October 2017 and September 2018. The incidence of delayed bleeding was compared with that in a historical control group of 116 patients treated with conventional PPI. We also evaluated risk factors associated with delayed bleeding. Delayed bleeding was observed in 8 of 50 patients (16.0%), which was not dissimilar from the incidence in the historical control group (12.1%) (p=0.49). In the univariate analysis, age (> 70 years) (p=0.034), multiple antithrombotic drug use (p<0.01), procedure time (> 200 min) (p=0.038) and tumor size (> 40 mm) (p<0.01) were associated with delayed bleeding after gastric ESD, but vonoprazan was not (p=0.49). Vonoprazan may not be more effective than conventional PPIs in preventing delayed bleeding after gastric ESD in patients receiving antithrombotic therapy. |
| Keywords | vonoprazan endoscopic submucosal dissection antithrombotic drug gastric cancer |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-06 |
| Volume | volume74 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 245 |
| End Page | 250 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32577023 |
| Web of Science KeyUT | 000543363400008 |
| NAID | 120006862799 |
| reference | Oda I, Saito D, Tada M, Iishi H, Tanabe S, Oyama T, Doi T, Otani Y, Fujisaki J, Ajioka Y, Hamada T, Inoue H, Gotoda T and Yoshida S: A multicenter retrospective study of endoscopic resection for early gastric cancer. Gastric Cancer (2006) 9: 262-270.| Lian J, Chen S, Zhang Y and Qiu F: A meta-analysis of endoscopic submucosal dissection and EMR for early gastric cancer. Gastrointest Endosc (2012) 76: 763-770.| Park YM, Cho E, Kang HY and Kim JM: The effectiveness and safety of endoscopic submucosal dissection compared with endoscopic mucosal resection for early gastric cancer: a systematic review and metaanalysis. Surg Endosc (2011) 25: 2666-2677.| Goto O, Fujishiro M, Oda I, Kakushima N, Yamamoto Y, Tsuji Y, Ohata K, Fujiwara T, Fujiwara J, Ishii N, Yokoi C, Miyamoto S, Itoh T, Morishita S, Gotoda T and Koike K: A multicenter survey of the management after gastric endoscopic submucosal dissection related to postoperative bleeding. Dig Dis Sci (2012) 57: 435-439.| Tsuji Y: Risk factors for bleeding after endoscopic submucosal dissection for gastric lesions. World Journal of Gastroenterology (2010) 16: 2913.| Furuhata T, Kaise M, Hoteya S, Iizuka T, Yamada A, Nomura K, Kuribayashi Y, Kikuchi D, Matsui A, Ogawa O, Yamashta S and Mitani T: Postoperative bleeding after gastric endoscopic submucosal dissection in patients receiving antithrombotic therapy. Gastric Cancer (2017) 20: 207-214.| Okada K, Yamamoto Y, Kasuga A, Omae M, Kubota M, Hirasawa T, Ishiyama A, Chino A, Tsuchida T, Fujisaki J, Nakajima A, Hoshino E and Igarashi M: Risk factors for delayed bleeding after endoscopic submucosal dissection for gastric neoplasm. Surg Endosc (2011) 25: 98-107.| Dong J, Wei K, Deng J, Zhou X, Huang X, Deng M and Lu M: Effects of antithrombotic therapy on bleeding after endoscopic submucosal dissection. Gastrointest Endosc (2017) 86: 807-816.| Kono Y, Obayashi Y, Baba Y, Sakae H, Gotoda T, Miura K, Kanzaki H, Iwamuro M, Kawano S, Kawahara Y, Tanaka T and Okada H: Postoperative bleeding risk after gastric endoscopic submucosal dissection during antithrombotic drug therapy. J Gastroenterol Hepatol (2018) 33: 453-460.| Tounou S, Morita Y and Hosono T: Continuous aspirin use does not increase post-endoscopic dissection bleeding risk for gastric neoplasms in patients on antiplatelet therapy. Endosc Int Open (2015) 3: E31-38.| Gotoda T, Hori K, Iwamuro M, Kono Y, Miura K, Kanzaki H, Kawano S, Kawahara Y and Okada H: Evaluation of the bleeding risk with various antithrombotic therapies after gastric endoscopic submucosal dissection. Endosc Int Open (2017) 5: E653-E662.| Uedo N, Takeuchi Y, Yamada T, Ishihara R, Ogiyama H, Yamamoto S, Kato M, Tatsumi K, Masuda E, Tamai C, Yamamoto S, Higashino K, Iishi H and Tatsuta M: Effect of a proton pump inhibitor or an H2-receptor antagonist on prevention of bleeding from ulcer after endoscopic submucosal dissection of early gastric cancer: a prospective randomized controlled trial. Am J Gastroenterol (2007) 102: 1610-1616.| Hamada K, Uedo N, Tonai Y, Arao M, Suzuki S, Iwatsubo T, Kato M, Shichijo S, Yamasaki Y, Matsuura N, Nakahira H, Kanesaka T, Yamamoto S, Akasaka T, Hanaoka N, Takeuchi Y, Higashino K, Ishihara R, Okada H, Iishi H, Fukui K and Shimokawa T: Efficacy of vonoprazan in prevention of bleeding from endoscopic submucosal dissection-induced gastric ulcers: a prospective randomized phase II study. J Gastroenterol (2018).| Kagawa T, Iwamuro M, Ishikawa S, Ishida M, Kuraoka S, Sasaki K, Sakakihara I, Izumikawa K, Yamamoto K, Takahashi S, Tanaka S, Matsuura M, Hasui T, Wato M and Inaba T: Vonoprazan prevents bleeding from endoscopic submucosal dissection-induced gastric ulcers. Aliment Pharmacol Ther (2016) 44: 583-591.| Kato M, Uedo N, Hokimoto S, Ieko M, Higuchi K, Murakami K and Fujimoto K: Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment: 2017 Appendix on Anticoagulants Including Direct Oral Anticoagulants. Dig Endosc (2018) 30: 433-440.| Fujimoto K, Fujishiro M, Kato M, Higuchi K, Iwakiri R, Sakamoto C, Uchiyama S, Kashiwagi A, Ogawa H, Murakami K, Mine T, Yoshino J, Kinoshita Y, Ichinose M, Matsui T and Japan Gastroenterological Endoscopy S: Guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment. Dig Endosc (2014) 26: 1-14.| Kawai T, Oda K, Funao N, Nishimura A, Matsumoto Y, Mizokami Y, Ashida K and Sugano K: Vonoprazan prevents low-dose aspirin-associated ulcer recurrence: randomised phase 3 study. Gut (2018) 67: 1033-1041.| |
| JaLCDOI | 10.18926/AMO/59952 |
|---|---|
| FullText URL | 74_3_215.pdf |
| Author | Chou, Hsi-Hsien| |
| Abstract | Due to cultural traditions, most Taiwanese do not have an advance directive or healthcare proxy. We explored how patients with mild dementia in Taiwan may still make self-determined decisions concerning advance directives for their healthcare and end-of-life care choices as the disease progresses. We examined 260 respondents with mild dementia at a Taiwan medical center: 199 patients who agreed (and 61 patients who disagreed) with the concept of advance directives completed a structured questionnaire. Multiple logistic regression models to determine the between-group differences revealed that the following were positively associated with approval of end-of-life directives: maintaining one’s quality of life (adjusted odds ratio [AOR], 2.44; 95% CI: 1.07-5.53), discussion with family members (AOR, 3.50; 95% CI: 1.49-8.26), and friend support networks (AOR, 3.36; 95% CI: 1.34-8.43). Cardiopulmonary resuscitation (AOR, 0.27; 95% CI: 0.09-0.79) was negatively associated with approval. There was also a positive association between the support of the legal validity of end-of-life directives (OR, 1.93; 95% CI: 1.07-3.48), without other confounding factors. In Taiwanese society, we remain mindful of cultural influences that may impact patients, including maintaining one’s quality of life, discussion with family members, and friend/support networks. These influences may help dementia patients complete their advance directives. |
| Keywords | advance directive dementia patient autonomy quality of life culture |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-06 |
| Volume | volume74 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 215 |
| End Page | 220 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32577019 |
| Web of Science KeyUT | 000543363400005 |
| NAID | 120006862794 |
| JaLCDOI | 10.18926/AMO/59949 |
|---|---|
| FullText URL | 74_3_191.pdf |
| Author | Ohashi, Keiji| Sada, Ken-Ei| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Asano, Sumie Hiramatsu| Miyawaki, Yoshia| Morishita, Michiko| Katsuyama, Eri| Watanabe, Haruki| Tatebe, Noriko| Narazaki, Mariko| Matsumoto, Yoshinori| Sunahori-Watanabe, Katsue| Kawabata, Tomoko| Yajima, Nobuyuki| Wada, Jun| |
| Abstract | Chronic damage accumulation affects not only mortality but also quality of life in patients with systemic lupus erythematosus (SLE). Risk factors for chronic damage were explored in SLE through different onset eras. Two hundred forty-five patients at Okayama University Hospital and Showa University Hospital were divided into three groups based on the onset era: a past-onset group (onset before 1995; n=83), middle-onset group (1996-2009; n=88), and recent-onset group (after 2010; n=74). The mean Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) score as an index of chronic damage was 1.93, 1.24, and 0.53 in the past-, middle-, and recent-onset groups, respectively. In the pastonset group, the total SDI score was significantly associated with glucocorticoid monotherapy by linear regression analysis (β-coefficient [β]=0.63; 95% confidence interval [CI], 0.21-1.05) and C-reactive protein levels (β=0.67; 95% CI, 0.27-1.07). In the middle-onset group, the total SDI score was significantly associated with the SLE Disease Activity Index at registration (β=0.09; 95% CI, 0.03-0.12). Reducing the accumulation of chronic damage in SLE patients might be possible with the concomitant use of immunosuppressants and tight control of disease activity. |
| Keywords | systemic lupus erythematosus chronic damage glucocorticoids, disease activity disease duration |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-06 |
| Volume | volume74 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 191 |
| End Page | 198 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32577016 |
| Web of Science KeyUT | 000543363400002 |
| NAID | 120006862791 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ishihara, Ryo| Miyatake, Takahisa| |
| Keywords | Copulation Courtship Mating duration Panorpa japonica |
| Published Date | 2020-03-14 |
| Publication Title | Journal of Ethology |
| Volume | volume38 |
| Publisher | Springer |
| Start Page | 233 |
| End Page | 239 |
| ISSN | 02890771 |
| NCID | AA10754455 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1007/s10164-020-00645-3 |
| Web of Science KeyUT | 000527376500012 |
| Related Url | isVersionOf https://doi.org/10.1007/s10164-020-00645-3 |
| JaLCDOI | 10.18926/AMO/58277 |
|---|---|
| FullText URL | 74_2_171.pdf |
| Author | Okita, Atsushi| Yoshida, Osamu| Murakami, Masakazu| |
| Abstract | A 76-year-old Japanese man was transferred to our hospital to undergo rehabilitation after traffic accident-related injuries. Seven days post-admission, he presented with abdominal pain and an 8-cm lump in the right inguinal region. He was diagnosed with an incarcerated inguinal hernia and underwent elective surgery the day after manual reduction. He had a normal vermiform appendix which was observed to have adhered to the right indirect hernia sac. An appendectomy and hernia repair using lightweight mesh were performed. We discuss the surgical management of this rare incarcerated Amyand’s hernia and the relevant literature. |
| Keywords | Amyand’s hernia incarcerated inguinal hernia appendectomy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 171 |
| End Page | 174 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341593 |
| Web of Science KeyUT | 000528278500012 |
| NAID | 120006839456 |
| JaLCDOI | 10.18926/AMO/58273 |
|---|---|
| FullText URL | 74_2_145.pdf |
| Author | Otsuki, Hideo| Yamasaki, Tomoya| Hori, Shunsuke| Aoki, Hiroshi| Kosaka, Takeo| Uehara, Shinya| Fujio, Kei| |
| Abstract | To investigate the efficacy of mirabegron for lower urinary tract symptoms in patients with an indwelling ureteral stent after ureterorenoscopic lithotripsy. This was a prospective follow-up study of 76 patients with stent-related symptoms (SRSs). Patients with upper urinary calculi who were pre-stented for > 2 weeks before lithotripsy were examined for the presence of SRSs by tests including the International Prostate Symptom Score (IPSS), OAB Symptom Score (OABSS), and urinary bother and pain measured by a Visual Analogue Scale (VAS) before lithotripsy. Mirabegron (50 mg/day) was prescribed post-lithotripsy for 2 weeks. SRSs were assessed at the time of stent removal. The IPSS scores improved significantly from 16.2 to 14.3 (p<0.001) and the IPSS-QoL scores decreased significantly from 5.0 to 4.6 (p=0.012). The OABSS scores improved significantly from 7.7 to 6.8 (p=0.006), and the urinary urgency scores (OABSS-Q3) decreased significantly from 3.24 to 2.68 (p<0.001). The number of nocturia episodes decreased significantly from 2.5 to 2.2 (p=0.045). Urinary bother and pain assessed by the VAS declined from 4.2 and 3.1 to 3.8 (p=0.15) and 2.5 (p=0.075), respectively. Mirabegron significantly improved SRSs and the number of nocturia episodes due to a ureteral stent. |
| Keywords | stent-related symptoms overactive bladder mirabegron ureterorenoscopic lithotripsy ureteral stent |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 145 |
| End Page | 150 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341589 |
| Web of Science KeyUT | 000528278500008 |
| NAID | 120006839452 |
| JaLCDOI | 10.18926/AMO/58272 |
|---|---|
| FullText URL | 74_2_137.pdf |
| Author | Isozaki, Hiroshi| Yamamoto, Yasuhisa| Sakai, Kunihiko| Sho, Tatuo| Ishihara, Kiyohiro| Murakami, Shigeki| Matsumoto, Sasau| Takama, Takehiro| |
| Abstract | Mucinous carcinoma (MC) of the breast is a rare and special type of malignancy, with a substantial amount of extracellular mucin. We compared the clinicopathological features and the long-term survival of MC patients with those of invasive ductal carcinoma-no special type (IDC-NST) patients, and we examined prognostic factors of MC. A total of 116 patients with mucinous carcinoma and 3,258 patients with IDC-NST who underwent surgery at our hospital (1977-2008) were enrolled. The 10-year overall survival rate and breast cancer-specific survival rate (BSS) of the MC patients (88.3%, 93.7%) were both significantly higher than those of IDC-NST patients (81.6%, 85.0%) (p=0.015, p=0.005, respectively). A Cox regression analysis demonstrated that MC tended to be an independent prognostic factor (hazard ratio 0.44, p=0.098). The BSS of the MC patients with positive lymph node (LN) metastasis was significantly poorer than that of the patients without it, by univariate analysis (p=0.002). The tumor size in the MC patients with positive LN metastasis (mean 3.2 cm) was significantly larger than that in the patients without it (mean 1.9 cm) (p=0.0004). Although a Cox regression analysis revealed no independent factor, MC patients with positive LN metastasis should be treated for advanced invasive ductal breast cancer. |
| Keywords | breast cancer mucinous carcinoma clinicopathological features long-term prognosis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 137 |
| End Page | 143 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341588 |
| Web of Science KeyUT | 000528278500007 |
| NAID | 120006839451 |
| reference | Clayton F: Pure mucinous carcinomas of breast: morphologic features and prognostic correlates. Hum Pathol (1986) 17: 34-38.| Avisar E, Khan MA, Axelrod D and Oza K: Pure mucinous carcinoma of the breast: a clinicopathologic correlation study. Ann Surg Oncol (1998) 5: 447-451.| Komenaka IK, El-Tamer MB, Troxel A, Hamele-Bena D, Joseph KA, Horowitz E, Ditkoff BA and Schnabel FR: Pure mucinous carcinoma of the breast. Am J Surg (2004) 187: 528-532.| Barkley CR, Ligibel JA, Wong JS, Lipsitz S, Smith BL and Golshan M: Mucinous breast carcinoma: a large contemporary series. Am J Surg (2008) 196: 549-551.| André S, Cunha F, Bernardo M, Meneses e Sousa J, Cortez F and Soares J: Mucinous carcinoma of the breast: a pathologic study of 82 cases. J Surg Oncol (1995) 58: 162-167.| Skotnicki P, Sas-Korczynska B, Strzepek L, Jakubowicz J, Blecharz P, Reinfuss M and Walasek T: Pure and Mixed Mucinous Carcinoma of the Breast: A Comparison of Clinical Outcomes and Treatment Results. Breast J (2016) 22: 529-534.| Di Saverio S, Gutierrez J and Avisar E: A retrospective review with long term follow up of 11,400 cases of pure mucinous breast carcinoma. Breast Cancer Res Treat (2008) 111: 541-547.| Fu J, Wu L, Jiang M, Li D, Jiang T, Hong Z, Wang F and Li S: Clinical Nomogram for Predicting Survival Outcomes in Early Mucinous Breast Cancer. PLoS One (2016) 11: e0164921.| Japanese Breast Cancer Society: General Rules for Clinical and Pathological Recording of Breast Cancer, 18th Ed, Kanehara & Co., Ltd., Tokyo, (2018) (in Japanese).| American College of Radiology: Breast Imaging Reporting and Data System-Mammography. fourth edition, (2003).| UICC (Union for International Cancer Control): TNM classification of malignant tumors, 8th Ed, John Wiley & Sons, Ltd., (2017).| Kanda Y: Investigation of the freely available easy-to-use software ʻEZRʼ for medical statistics. Bone Marrow Transplant (2013) 48: 452-458.| Bae SY, Choi MY, Cho DH, Lee JE, Nam SJ and Yang JH: Mucinous carcinoma of the breast in comparison with invasive ductal carcinoma: clinicopathologic characteristics and prognosis. J Breast Cancer (2011) 14: 308-313.| Park S, Koo J, Kim JH, Yang WI, Park BW and Lee KS: Clinicopathological characteristics of mucinous carcinoma of the breast in Korea: comparison with invasive ductal carcinoma-not otherwise specified. Korean Med Sci (2010) 25: 361-368.| Komaki K, Sakamoto G, Sugano H, Morimoto T and Monden Y: Mucinous carcinoma of the breast in Japan. A prognostic analysis based on morphologic features. Cancer (1988) 61: 989-996.| Wilson TE, Helvie MA, Oberman HA and Joynt LK: Pure and mixed mucinous carcinoma of the breast: pathologic basis for differences in mammographic appearance. AJR Am J Roentgenol (1995) 165: 285-289.| |
| Title Alternative | The 2018 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2018 Sunada Prize) |
|---|---|
| FullText URL | 131_123.pdf |
| Author | Umebayashi, Ryoko| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2019-12-02 |
| Volume | volume131 |
| Issue | issue3 |
| Start Page | 123 |
| End Page | 125 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.131.123 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2019 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.131.123 |
| NAID | 130007782634 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Knaup, Emily| Nosaka, Nobuyuki| Yorifuji, Takashi| Tsukahara, Kohei| Naitou, Hiromichi| Tsukahara, Hirokazu| Nakao, Atsunori| the JaRPAC Study Group| |
| Keywords | Decision support Intensive care Length of stay Mortality Outcome Pediatric Risk Prediction rules Scoring system |
| Published Date | 2019-07-29 |
| Publication Title | Journal of Intensive Care |
| Volume | volume7 |
| Publisher | BMC |
| Start Page | 38 |
| ISSN | 2052-0492 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). |
| File Version | publisher |
| PubMed ID | 31384469 |
| DOI | 10.1186/s40560-019-0392-2 |
| Web of Science KeyUT | 000477892900001 |
| Related Url | isVersionOf https://doi.org/10.1186/s40560-019-0392-2 |
| JaLCDOI | 10.18926/58035 |
|---|---|
| Title Alternative | Development of Academic Japanese Training Course for Students at the Discovery Program for Global Learners, Okayama University |
| FullText URL | biess_4_038_049.pdf |
| Author | USHIDA, Eiko| |
| Abstract | 岡山大学グローバル・ディスカバリー・プログラムは英語だけで学位が取れる新しいプログラムであるが, 制度上他学部開講の授業も履修することが可能である。全学日本語の日本語コースで日本語「を」学ぶ学生とともに他学部で日本語「で」学ぶディスカバリー生も徐々に増えている。そこで他学部の授業や教養科目を履修するディスカバリー生を対象にアカデミック・ジャパニーズ科目を新規開講することになった。Backward Design，Differentiated Instruction，Learning Strategy Instruction の手法を利用し，授業をこなし単位を取得することを目標に，学生が限られた日本語能力で最大限に対応できる「自分に合う」学習ストラテジーを開拓できるコースの開発と履修状況を報告する。 |
| Keywords | グローバル・ディスカバリー・プログラム アカデミック・ジャパニーズ Backward Design Differentiated Instruction 学習ストラテジー |
| Publication Title | Bulletin of Institute for Education and Student Services, Okayama University |
| Published Date | 2019-12-30 |
| Volume | volume4 |
| Start Page | 38 |
| End Page | 49 |
| ISSN | 2432-9665 |
| language | Japanese |
| File Version | publisher |
| NAID | 120006812101 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ejiri Kentaro| Akagi, Satoshi| Nakamura, Kazufumi| Amioka, Naofumi| Ichikawa, Keishi| Yagi, Takahito| Ito, Hiroshi| |
| Keywords | Rendu-Osler-Weber syndrome arteriovenous malformation pulmonary haemorrhage |
| Published Date | 2019-12-18 |
| Publication Title | Pulmonary Circulation |
| Volume | volume9 |
| Issue | issue4 |
| Publisher | SAGE Publications Inc |
| ISSN | 2045-8932 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2019. |
| File Version | publisher |
| PubMed ID | 31903186 |
| DOI | 10.1177/2045894019896677 |
| Web of Science KeyUT | 000503484500001 |
| Related Url | isVersionOf https://doi.org/10.1177/2045894019896677 |
| JaLCDOI | 10.18926/AMO/57947 |
|---|---|
| FullText URL | 74_1_7.pdf |
| Author | Sanki, Tomoaki| Endo, Hirosuke| Tetsunaga, Tomonori| Furumatsu, Takayuki| Yamada, Kazuki| Ozaki, Toshifumi| |
| Abstract | We investigated the relationship between the initial contact status and stress shielding in total hip arthroplasty (THA) using fit-and-fill type straight-stem implants. In addition we evaluated the clinical and radiographic outcomes. Subjects were 100 hips of 94 patients who underwent THA and were followed-up for ≥10 years. Contact areas with the femoral cortical bone were investigated according to the zonal distribution of Gruen using postoperative CT images. Depending on the number of contact areas, the patients were classified into high contact [HC], medium contact [MC], and low contact [LC] groups. Radiographic and clinical outcomes were evaluated. In the HC group (20 hips), severe stress shielding was observed in 12 hips, which was statistically significant (p=0.008). In the LC group (29 hips), mild stress shielding was observed in 27 hips which was statistically significant (p<0.001). No significant differences were observed among the 3 groups in clinical outcomes, Harris hip score (p=0.719) or Japanese Orthopedic Association (JOA) score (p=0.301). In insertion of cementless collared fit-and-fill type straight-stem implants, severe late stress shielding of the femoral bone may occur if high contact of the femoral component is achieved. However, the degree of stress shielding does not result in adverse clinical outcomes. |
| Keywords | fit-and-fill stress shielding cementless straight stem total hip arthroplasty |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-02 |
| Volume | volume74 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 7 |
| End Page | 15 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32099243 |
| Web of Science KeyUT | 000516606200002 |
| NAID | 120006795614 |
| JaLCDOI | 10.18926/AMO/57946 |
|---|---|
| FullText URL | 74_1_1.pdf |
| Author | Chen, Yuehua| Ohara, Toshiaki| Xing, Boyi| Qi, Jiping| Noma, Kazuhiro| Matsukawa, Akihiro| |
| Abstract | Iron is a trace but vital element in the human body and is necessary for a multitude of crucial processes in life. However, iron overload is known to induce carcinogenesis via oxidative stress. Cancer cells require large amounts of iron for their rapid division and cell growth. Iron was recently found to play a role in cancer stem cells (CSCs); it maintains stemness during development. Iron also plays an important role in stemness by moderating reactive oxygen species. Thus, iron metabolism in CSCs is a promising therapeutic target. In this review, we summarize the roles of iron in cancer cells and CSCs. We also summarize anti-cancer therapeutic studies with iron chelators and describe our expectation of a new therapeutic strategy for CSCs on the basis of our findings. |
| Keywords | cancer stem cell stemness iron chelation chemotherapy |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-02 |
| Volume | volume74 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 1 |
| End Page | 6 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32099242 |
| Web of Science KeyUT | 000516606200001 |
| NAID | 120006795613 |
| FullText URL | DMJ38_5_798.pdf |
|---|---|
| Author | Kominami, Nao| Shimada, Yasushi| Hosaka, Keiichi| Minh Nguyet Luong| Yoshiyama, Masahiro| Sadr, Alireza| Sumi, Yasunori| Tagami, Junji| |
| Keywords | Dentin Internal fracture Microtensile bond strength test SS-OCT |
| Published Date | 2019-09-27 |
| Publication Title | Dental Materials Journal |
| Volume | volume38 |
| Issue | issue385 |
| Publisher | Japanese Society for Dental Materials and Devices |
| Start Page | 798 |
| End Page | 805 |
| ISSN | 0287-4547 |
| NCID | AA10443149 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 The Japanese Society for Dental Materials and Devices |
| File Version | publisher |
| PubMed ID | 31341147 |
| DOI | 10.4012/dmj.2018-232 |
| Web of Science KeyUT | 000500359500015 |
| Related Url | isVersionOf https://doi.org/10.4012/dmj.2018-232 |
| FullText URL | DMJ38_5_779.pdf |
|---|---|
| Author | Rima Zakzuk Alshahni| Shimada, Yasushi| Zhou, Yuan| Yoshiyama, Masahiro| Sadr, Alireza| Sumi, Yasunori| Tagami, Junji| |
| Keywords | Bottom Dentin-enamel junction Gap SS-OCT Self-etch adhesive |
| Published Date | 2019-09-27 |
| Publication Title | Dental Materials Journal |
| Volume | volume38 |
| Issue | issue5 |
| Publisher | Japanese Society for Dental Materials and Devices |
| Start Page | 779 |
| End Page | 789 |
| ISSN | 0287-4547 |
| NCID | AA10443149 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 The Japanese Society for Dental Materials and Devices |
| File Version | publisher |
| PubMed ID | 31341148 |
| DOI | 10.4012/dmj.2018-265 |
| Web of Science KeyUT | 000500359500013 |
| Related Url | isVersionOf https://doi.org/10.4012/dmj.2018-265 |
| FullText URL | CH38_1_14.pdf |
|---|---|
| Author | Tanabe, Shintaro| Kasuya, Eiiti| Miyatake, Takahisa| |
| Keywords | Habituation Hyla japonica individual variation sexual difference predation |
| Published Date | 2019-02-28 |
| Publication Title | Current Herpetology |
| Volume | volume38 |
| Issue | issue1 |
| Publisher | Herpetological Society of Japan |
| Start Page | 14 |
| End Page | 22 |
| ISSN | 1345-5834 |
| NCID | AA12410796 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.5358/hsj.38.14 |
| Web of Science KeyUT | 000483742900003 |
| Related Url | isVersionOf https://doi.org/10.5358/hsj.38.14 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Watanabe, Atsuyuki| Fujimura, Osamu| |
| Keywords | Tachycardiav Atrioventricular node reentry Cardiac defibrillatorIschemic cardiomyopathy |
| Published Date | 2020-02-29 |
| Publication Title | Indian Pacing and Electrophysiology Journal |
| Volume | volume20 |
| Issue | issue1 |
| Publisher | Elsevier |
| Start Page | 35 |
| End Page | 38 |
| ISSN | 09726292 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. |
| File Version | publisher |
| DOI | 10.1016/j.ipej.2019.12.004 |
| Related Url | isVersionOf https://doi.org/10.1016/j.ipej.2019.12.004 |
| FullText URL | psychogeriatrics19_6_566.pdf table.pdf |
|---|---|
| Author | Takenoshita, Shintaro| Terada, Seishi| Oshima, Etsuko| Yamaguchi, Megumi| Hayashi, Satoshi| Hinotsu, Kenji| Esumi, Satoru| Shinya, Takayoshi| Yamada, Norihito| |
| Keywords | depression elderly Lewy body disease metaiodobenzylguanidine somatic anxiety |
| Published Date | 2019-02-27 |
| Publication Title | Psychogeriatrics |
| Volume | volume19 |
| Issue | issue6 |
| Publisher | Wiley |
| Start Page | 566 |
| End Page | 573 |
| ISSN | 1346-3500 |
| NCID | AA11919302 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30809892 |
| DOI | 10.1111/psyg.12439 |
| Web of Science KeyUT | 000495852300005 |
| Related Url | isVersionOf https://doi.org/10.1111/psyg.12439 |
| JaLCDOI | 10.18926/AMO/57716 |
|---|---|
| FullText URL | 73_6_517.pdf |
| Author | Hosogi, Mika| Shiode, Yusuke| Morizane, Yuki| Kimura, Shuhei| Hosokawa, Mio| Doi, Shinichiro| Toshima, Shinji| Takahashi, Kosuke| Fujiwara, Atsushi| Shiraga, Fumio| |
| Abstract | We investigated the effectiveness of a treat-and-extend regimen (TAE) of intravitreal ranibizumab injections for macular edema (ME) due to branch retinal vein occlusion (BRVO). We retrospectively examined 2-year results of 32 eyes of 32 patients who underwent TAE to treat ME due to BRVO. The patients whose treatment interval extended to ≥ 12 weeks were switched to a pro re nata regimen (PRN). For the patients whose treatment interval was <12 weeks, TAE was continued. At 2 years, 10 eyes had required no additional injections after the initial treatment period [recurrence(−) group], whereas the other 22 eyes required additional treatment [recurrence(+) group]. Among the recurrence(+) patients, 11 eyes (34.4% of total) were eventually switched from TAE to PRN; the other 11 eyes (34.4%) continued TAE for 2 years. Visual acuity and central retinal thickness were significantly improved in both the recurrence(+) and (−) groups, and there was no significant betweengroup difference in visual acuity at 2 years. Univariate analyses revealed significant differences in visual acuity (p=0.004), age (p=0.014), and vessel occlusion site (p=0.018) between these groups. Our results suggest that TAE may be effective for BRVO patients with lower visual acuity, older age, and occlusion of a major vein. |
| Keywords | branch retinal vein occlusion macular edema anti-vascular endothelial growth factor ranibizumab treat-and-extend regimen |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-12 |
| Volume | volume73 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 517 |
| End Page | 522 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31871334 |
| Web of Science KeyUT | 000503431400007 |
