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JaLCDOI 10.18926/AMO/63409
FullText URL 76_2_155.pdf
Author Kimura, Jiro| Okabayashi, Takehiro| Sui, Kenta| Tabuchi, Motoyasu| Iwata, Jun| Hata, Yasuhiro| Iiyama, Tatsuo| Ono, Noriaki|
Abstract Small bowel metastasis from renal cell carcinoma (RCC) is rare, and its clinicopathological characteristics are unclear; thus, we revisited the concept of this tumor and reviewed its diagnostic and treatment modalities. We filtered MEDLINE searches of articles published in English between 1950 and 2019, and identified 100 patients who had undergone treatment, including 1 patient from our clinic. We extracted patient characteristics, treatment, and prognostic data, resulting in clinicopathological data on 100 patients (83 men, 17 women). Mean age was 63 years (range, 16-86 years). Tumor sites were duodenum, jejunum, ileum, and multiple sites in 30, 37, 25, and 7 patients, respectively. The 1-, 3-, and 5-year overall survival rates after diagnosis were 53.0%, 36.0%, and 36.0%. Curative resection patients showed 62.1% 5-year survival after surgery, vs. 27.5% in noncurative surgical management cases. Good prognoses can be expected if these tumors are identified early for complete removal. Surgery is the only curative option. To determine the best management strategy and improve prognostic accuracy, we continue to collect and analyze epidemiological and pathological data. Although this condition is rare, surgery should be considered if curative resection is expected. Prognosis after curative resection is not poor, but recurrence is not unlikely.
Keywords renal cell carcinoma small bowel metastasis intestine tumor
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 155
End Page 165
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503443
Web of Science KeyUT 000792374900007
JaLCDOI 10.18926/AMO/63408
FullText URL 76_2_145.pdf
Author Qin, Yi| Liu, Linlin| Zhu, Fanghui| Lu, Huazhen| Huang, Mingliu|
Abstract With rapidly aging populations, family care functions can become weakened, and community health services often lack unified standards. A standardized and professional community home-based long-term care model (CHLCM) for the elderly is urgently needed in many regions of China and in other countries. Here, we explored the indicators of the need for a CHLCM among elderly individuals, and we constructed a CHLCM. We created and distributed a questionnaire regarding the requirement of long-term care services, based on a literature review. The two-rounds Delphi method was used, involving 20 experts who were randomly selected from among the medical universities, community health service centers, and nursing homes in Nanning, Guangxi, China. The experts’ enthusiasm rates in the questionnaire’s two rounds were 95% and 100%, respectively. The authentic coefficient of the experts’ consulting was 0.857, and that of the experts’ academic level was 0.835; the judgement coefficient was 0.880 and the familiar coefficient was 0.855. The CHLCM includes service content and an evaluation. The coordination coefficients for the two primary, eight secondary, and 29 tertiary indicators were 0.200, 0.386, and 0.184, respectively (p<0.05). The experts’ enthusiasm and authority were high. The coordination of the experts’ agreement was sufficient, and the analysis results were reliable. The CHLCM includes 29 items that provide a foundation and references for the formulation of concrete indicators and subsequent research.
Keywords community home-based long-term care elderly indicator system
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 145
End Page 154
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503442
Web of Science KeyUT 000792374900006
JaLCDOI 10.18926/AMO/63406
FullText URL 76_2_129.pdf
Author Kubo, Kotaro| Nakamura, Keiichiro| Okamoto, Kazuhiro| Matsuoka, Hirofumi| Ida, Naoyuki| Haruma, Tomoko| Ogawa, Chikako| Masuyama, Hisashi|
Abstract Cancer patients have increased risk of venous thromboembolism (VTE) that must be assessed before treatment. This study aimed to determine effective VTE biomarkers in gynecologic cancer (GC). We investigated the correlation between D-dimer levels, Khorana risk score (KRS), Glasgow prognostic score (GPS), and VTE in 1499 GC patients (583 cervical cancer (CC), 621 endometrial cancer (EC), and 295 ovarian cancer (OC) patients) treated at our institution between January 2008 and December 2019. χ2 and Mann–Whitney U-tests were used to determine statistical significance. We used receiver operating characteristic-curve analysis to evaluate the discriminatory ability of each parameter. D-dimer levels were significantly correlated with KRS and GPS in patients with GC. VTE was diagnosed in 11 CC (1.9%), 27 EC (4.3%), and 39 OC patients (13.2%). Optimal D-dimer cut-off values for VTE were 3.1, 3.2, and 3.9 μg/ml in CC, EC and OC patients, respectively. D-dimer could significantly predict VTE in all GC patients. Furthermore, D-dimer combined with GPS was more accurate in predicting VTE than other VTE biomarkers in stage IIIC and IVA OC (AUC: 0.846; p<0.001). This study demonstrates that combined D-dimer and GPS are useful in predicting VTE in patients with OC.
Keywords D-dimer gynecologic cancer venous thromboembolism
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 129
End Page 135
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503440
Web of Science KeyUT 000792374900004
JaLCDOI 10.18926/AMO/63404
FullText URL 76_2_113.pdf
Author Namio, Keiichi| Miyatake, Nobuyuki| Hishii, Shuhei| Kondo, Takashi| Nishi, Hiroyuki| Katayama, Akihiko| Ujike, Kazuhiro| Koumoto, Kiichi| Suzuki, Hiromi| Hashimoto, Hiroo|
Abstract This study aimed to investigate the link between prolonged sedentary bouts and health-related quality of life (QOL) in patients on chronic hemodialysis (CHD). A total of 84 outpatients on CHD, aged 71.6±11.8 years, were enrolled in this cross-sectional study. Parameters for prolonged sedentary bouts [i.e., ≧ 30 min (% and bout) and ≧ 60 min (% and bout)] were measured using a triaxial accelerometer. Health-related QOL (HRQOL) was evaluated by the Euro-QOL (EQ-5D). Clinical parameters were obtained from medical records. Relatively prolonged sedentary bouts (%) were 44.0±18.2 (≧ 30 min) and 29.8±16.5 (≧ 60 min) for total days. Prolonged sedentary bouts (bouts) were 6.2±2.7 (≧ 30 min) and 2.7±1.6 (≧ 60 min) for total days. EQ-5D scores were 0.728±0.220. All prolonged sedentary bout parameters were negatively correlated with EQ-5D scores, except for prolonged sedentary bouts (≧ 60 min) (min) and relatively prolonged sedentary bouts (%) on hemodialysis days. Multiple regression analysis showed that prolonged sedentary bout parameters were an important factor in EQ-5D scores even after adjusting for confounding factors for total and non-hemodialysis days. Our results suggested that prolonged sedentary bouts were closely associated with HRQOL in patients on CHD, especially on non-hemodialysis days.
Keywords prolonged sedentary bouts hemodialysis EQ-5D QOL
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-04
Volume volume76
Issue issue2
Publisher Okayama University Medical School
Start Page 113
End Page 119
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35503438
Web of Science KeyUT 000792374900002
FullText URL fulltext20220413-5.pdf
Author Tanabe, Ryo| Hongo, Takashi| Mandai, Yasuhiro| Inaba, Mototaka| Yorifuji, Takashi| Nakao, Atsunori| Elmer, Jonathan| Naito, Hiromichi|
Keywords DNAR EMT OHCA Stress
Published Date 2022-03-03
Publication Title Resuscitation
Volume volume173
Publisher Elsevier BV
Start Page 61
End Page 68
ISSN 0300-9572
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Author(s)
File Version publisher
PubMed ID 35143903
DOI 10.1016/j.resuscitation.2022.01.028
Web of Science KeyUT 000767483800011
Related Url isVersionOf https://doi.org/10.1016/j.resuscitation.2022.01.028
FullText URL fulltext.pdf
Author Yamamoto, Norio| Mitsuhashi, Toshiharu| Tsuchihashi, Yuuki| Yorifuji, Takashi|
Keywords Tokyo 2020 Olympic and Paralympic Games COVID-19 pandemic synthetic control method causal effect ecological study
Published Date 2022-02-03
Publication Title Journal Of Personalized Medicine
Volume volume12
Issue issue2
Publisher MDPI
Start Page 209
ISSN 2075-4426
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 35207697
DOI 10.3390/jpm12020209
Web of Science KeyUT 000769713400001
Related Url isVersionOf https://doi.org/10.3390/jpm12020209
JaLCDOI 10.18926/AMO/63214
FullText URL 76_1_71.pdf
Author Tanaka, Masato| Sonawane, Sumeet| Fujiwara, Yoshihiro| Uotani, Koji| Arataki, Shinya| Yamauchi, Taro| Ye, Youchen| Misawa, Haruo|
Abstract The surgical treatment of pediatric atlantoaxial subluxation (AAS) in Down syndrome (DS) remains technically challenging due to radiation exposure and complications such as vertebral artery injury and nonunion. The established treatment is fixation with a C1 lateral mass screw and C2 pedicle screw (modified Goel technique). However, this technique requires fluoroscopy for C1 screw insertion. To avoid exposing the operating team to radiation we present here a new C-arm free O-arm navigated surgical procedure for pediatric AAS in DS. A 5-year-old male DS patient had neck pain and unsteady gait. Radiograms showed AAS with an atlantodental interval of 10 mm, and irreducible subluxation on extension. CT scan showed Os odontoideum and AAS. MRI demonstrated spinal cord compression between the C1 posterior arch and odontoid process. We performed a C-arm free O-arm navigated modified Goel procedure with postoperative halo-vest immobilization. At oneyear follow-up, good neurological recovery and solid bone fusion were observed. The patient had no complications such as epidural hematoma, infection, or nerve or vessel injury. This novel procedure is a useful and safe technique that protects surgeons and staff from radiation risk.
Keywords atlantoaxial fixation Down syndrome C-arm free O-arm navigation surgery modified Goel technique
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2022-02
Volume volume76
Issue issue1
Publisher Okayama University Medical School
Start Page 71
End Page 78
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35237001
Web of Science KeyUT 000762803800001
JaLCDOI 10.18926/AMO/63203
FullText URL 76_1_7.pdf
Author Takami, Masao| Yamamoto, Koichiro| Hanayama, Yoshihisa| Nakano, Yasuhiro| Hasegawa, Kou| Obika, Mikako| Hagiya, Hideharu| Furukawa, Masanori| Otsuka, Fumio|
Abstract Subclinical hypothyroidism (SCH) is diagnosed when serum thyrotropin (TSH) is elevated despite a normal thyroxine level and is known to increase the risk of metabolic disorders. This study was conducted to identify potential laboratory markers suspicious for latent SCH. We retrospectively reviewed 958 outpatients in whom thyroid functions had been examined. Eighty-five (9.1%) of the 939 analyzed subjects had SCH (73% females). In the SCH group, median serum TSH and FT4 levels were 5.04 μU/ml and 1.19 ng/dl, respectively, and auto-thyroid antibodies were detected in 53.8% of patients. SCH group patients were significantly older than patients in the euthyroid group, while there was no intergroup difference in BMI. However, 56.5% of the SCH patients were asymptomatic. In the SCH group, serum aspartate aminotransferase and low-density lipoprotein cholesterol (LDL-C) levels were significantly higher, and the estimated glomerular filtration rate (eGFR) was significantly lower than in the euthyroid group. Among patients less than 65 years of age, SCH patients tended to have lower eGFR and higher LDL-C than euthyroid patients. Age-dependent reductions of red blood cells and serum albumin were more prominent in the SCH than the euthyroid group. Biochemical changes with aging are useful as potential clues for suspecting latent SCH.
Keywords aging renal function cholesterol subclinical hypothyroidism thyroid function
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-02
Volume volume76
Issue issue1
Publisher Okayama University Medical School
Start Page 7
End Page 15
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 35236993
Web of Science KeyUT 000762812700002
FullText URL fulltext20220216-3.pdf Figure20220216-3.pdf Supplementary Figure20220216-3.pdf
Author Nishimura, Yoshito| Hagiya, Hideharu| Keitoku, Koichi| Koyama, Toshihiro| Otsuka, Fumio|
Note © 2021 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.ajic.2021.08.033] .|
Published Date 2022-01-28
Publication Title American Journal of Infection Control
Volume volume50
Issue issue2
Publisher Elsevier BV
Start Page 141
End Page 147
ISSN 0196-6553
NCID AA10617749
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Association for Professionals in Infection Control and Epidemiology, Inc.
File Version author
PubMed ID 34718066
DOI 10.1016/j.ajic.2021.08.033
Web of Science KeyUT 000749317500004
Related Url isVersionOf https://doi.org/10.1016/j.ajic.2021.08.033
FullText URL fulltext.pdf
Author Uraguchi, Kensuke| Maeda, Yukihide| Takahara, Junko| Omichi, Ryotaro| Fujimoto, Shohei| Kariya, Shin| Nishizaki, Kazunori| Ando, Mizuo|
Published Date 2021-10-22
Publication Title PLOS ONE
Volume volume16
Issue issue10
Publisher Public Library Science
Start Page e0258977
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 Uraguchi et al.
File Version publisher
PubMed ID 34679122
DOI 10.1371/journal.pone.0258977
Web of Science KeyUT 000733392900043
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0258977
FullText URL fulltext20220104-5.pdf
Author Suzuki, Etsuji| Tsuda, Toshihide| Mitsuhashi, Toshiharu| Mansournia, Mohammad Ali| Yamamoto, Eiji|
Keywords bias causality epidemiologic methods
Note © 2016 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/.
This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.annepidem.2016.09.008] .|
Published Date 2016-11
Publication Title Annals of Epidemiology
Volume volume26
Issue issue11
Publisher Elsevier BV
Start Page 788
End Page 793
ISSN 1047-2797
NCID AA10761439
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2016 Elsevier Inc.
File Version author
PubMed ID 27771142
DOI 10.1016/j.annepidem.2016.09.008
Web of Science KeyUT 000388546300011
Related Url isVersionOf https://doi.org/10.1016/j.annepidem.2016.09.008
FullText URL fulltext20220104-4.pdf
Author Suzuki, Etsuji| VanderWeele, Tyler J.|
Note © 2018 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.socscimed.2018.04.023] .|
Published Date 2018-8
Publication Title Social Science & Medicine
Volume volume210
Publisher Elsevier BV
Start Page 83
End Page 85
ISSN 0277-9536
NCID AA10627742
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2018 Elsevier Ltd.
File Version author
PubMed ID 29703448
DOI 10.1016/j.socscimed.2018.04.023
Web of Science KeyUT 000441652900021
Related Url isVersionOf https://doi.org/10.1016/j.socscimed.2018.04.023
FullText URL fulltext20220104-3.pdf
Author Suzuki, Etsuji| Tsuda, Toshihide| Yamamoto, Eiji|
Keywords bias causality confounding factors epidemiologic methods
Note © 2017 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.annepidem.2017.11.005] .|
Published Date 2018-1
Publication Title Annals of Epidemiology
Volume volume28
Issue issue1
Publisher Elsevier BV
Start Page 48
End Page 53
ISSN 1047-2797
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2017 Elsevier Inc.
File Version author
PubMed ID 29241736
DOI 10.1016/j.annepidem.2017.11.005
Web of Science KeyUT 000425081000008
Related Url isVersionOf https://doi.org/10.1016/j.annepidem.2017.11.005
FullText URL fulltext20220104-2.pdf
Author Suzuki, Etsuji| Yamamoto, Eiji|
Keywords Agonism Causality Counterfactual model Mediation Potential outcomes Sufficient cause model
Note This is a non-final version of an article published in final form in Suzuki, Etsuji; Yamamoto, Eiji Marginal Sufficient Component Cause Model, Epidemiology: November 2021 - Volume 32 - Issue 6 - p 838-845 doi: 10.1097/EDE.0000000000001411|
Published Date 2021-11
Publication Title Epidemiology
Volume volume32
Issue issue6
Publisher Ovid Technologies (Wolters Kluwer Health)
Start Page 838
End Page 845
ISSN 1044-3983
NCID AA10832184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders Copyright © 2021 Wolters Kluwer Health, Inc
File Version author
PubMed ID 34583368
DOI 10.1097/ede.0000000000001411
Web of Science KeyUT 000702003900011
Related Url isVersionOf https://doi.org/10.1097/ede.0000000000001411
FullText URL fulltext20220104-1.pdf
Author Suzuki, Etsuji| Yamamoto, Eiji|
Keywords Bradford Hill Causal inference Causal mechanisms Counterfactual Sufficient cause model Potential-outcome model
Note This is an Accepted Manuscript published by Springer Science.
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10654-021-00798-6|
Published Date 2021-9
Publication Title European Journal of Epidemiology
Volume volume36
Issue issue9
Publisher Springer Science and Business Media LLC
Start Page 899
End Page 908
ISSN 0393-2990
NCID AA10674491
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Springer Nature B.V. 2021
File Version author
PubMed ID 34564795
DOI 10.1007/s10654-021-00798-6
Web of Science KeyUT 000700703200003
Related Url isVersionOf https://doi.org/10.1007/s10654-021-00798-6
FullText URL fulltext.pdf
Author Tsuge, Mitsuru| Ikeda, Masanori| Matsumoto, Naomi| Yorifuji, Takashi| Tsukahara, Hirokazu|
Keywords atopic march atopic dermatitis food allergy allergic asthma allergic rhinitis skin barrier dysfunction alarmin group 2 innate lymphoid cells type 2 inflammation oxidative stress specific biomarker epidemiology phenotype early intervention emollient
Published Date 2021-11-19
Publication Title Children-Basel
Volume volume8
Issue issue11
Publisher MDPI
Start Page 1067
ISSN 2227-9067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2021 by the authors.
File Version publisher
PubMed ID 34828780
DOI 10.3390/children8111067
Web of Science KeyUT 000727145500001
Related Url isVersionOf https://doi.org/10.3390/children8111067
FullText URL fulltext.pdf
Author Matsumoto, Naomi| Kubo, Toshihide| Nakamura, Kazue| Mitsuhashi, Toshiharu| Takeuchi, Akihito| Tsukahara, Hirokazu| Yorifuji, Takashi|
Published Date 2021-11-26
Publication Title Scientific Reports
Volume volume11
Issue issue1
Publisher Nature Portfolio
Start Page 23004
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021
File Version publisher
PubMed ID 34837002
DOI 10.1038/s41598-021-02464-z
Web of Science KeyUT 000722925300029
Related Url isVersionOf https://doi.org/10.1038/s41598-021-02464-z
JaLCDOI 10.18926/AMO/62776
FullText URL 75_5_631.pdf
Author Yamamoto, Koichiro| Omura, Daisuke| Yamane, Mai| Son, Reina| Hasegawa, Kou| Honda, Hiroyuki| Obika, Mikako| Minao, Nozomu| Edahiro, Satoru| Yamada, Norihito| Otsuka, Fumio|
Abstract Anorexia nervosa (AN) is occasionally complicated with hypoglycemic coma, which may cause sudden death by unknown mechanisms. We present the case of a 36-year-old woman with recurrent comas and a nineteen-year history of AN. She was found in a coma with remarkable hypoglycemia (28 mg/dL). Her BMI was 11.1 kg/m2. Endocrine workup revealed extremely low serum levels of glucagon, IGF-I and insulin. Asymptomatic hypoglycemia occurred with liver injury in the refeeding process. An aberrant glucose metabolism due to liver damage might have been involved in her susceptibility to hypoglycemia. This case suggests a possible mechanism of hypoglycemic coma in AN.
Keywords anorexia nervosa glucagon hypoglycemic coma insulin-like growth factor-I liver injury
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2021-10
Volume volume75
Issue issue5
Publisher Okayama University Medical School
Start Page 631
End Page 636
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34703046
Web of Science KeyUT Recurrence of Hypoglycemic Coma in a Patient with Anorexia Nervosa Recurrence of Hypoglycemic Coma in a Patient with Anorexia Nervosa 000711568400001
NAID 120007166676
JaLCDOI 10.18926/AMO/62773
FullText URL 75_5_601.pdf
Author Mitsuhashi, Toshiharu|
Abstract Research suggests that the fundamental concepts of epidemiology cannot be sufficiently learned in traditional lectures, and interactive learning is necessary. However, few studies have investigated interactive epidemiology education in general, or peer instruction (PI) in particular. This study investigated the effect of PI. Study par-ticipants were fourth-year medical students. The attitude of participants in regard to PI learning was examined in a non-PI and a PI group. The Survey of Attitudes Toward Statistics (SATS) (containing six sub-categories) was conducted as a learning-attitudes index. The pre- and post-lecture scores were compared between the non-PI and PI groups using double robust (DR) estimation. The non-PI and PI groups consisted of 20 and 121 student participants, respectively. In DR estimation, affect exhibited the lowest SATS score changes, at −0.51 (95% confidence interval −0.78 to −0.24; p-value < 0.001), whereas effort exhibited the highest score changes of 0.01 (95% confidence interval −0.30 to 0.32; p-value = 0.952). The epidemiology lecture with PI did not increase the SATS scores. This might be due to issues related to the experimental design. Further research investigating the effects of interactive epidemiology education, it will be necessary to develop tools for assessing the learning of epidemiological concepts and to improve the research design.
Keywords medical students peer instruction epidemiological education learning attitude double robust esti-mation
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-10
Volume volume75
Issue issue5
Publisher Okayama University Medical School
Start Page 601
End Page 609
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34703043
Web of Science KeyUT 000711561600007
NAID 120007166673
JaLCDOI 10.18926/AMO/62769
FullText URL 75_5_567.pdf
Author Takase, Ryosuke| Hagiya, Hideharu| Honda, Hiroyuki| Nakano, Yasuhiro| Ogawa, Hiroko| Obika, Mikako| Ueda, Keigo| Kataoka, Hitomi| Hanayama, Yoshihisa| Otsuka, Fumio|
Abstract Influenza potentially has a high mortality rate when it affects the elderly. We aimed to examine the differences in clinical manifestations in patients with influenza according to their age. This multicenter prospective study was performed in six medical institutions in Okayama and Kagawa prefectures (Japan). Between December 1, 2019 and March 31, 2020, we collected data on adult patients diagnosed with influenza type A, who were strat-ified into younger (20-49 years), middle-aged (50-64 years), and older groups (≥ 65 years). We compared the presence or absence of fever, respiratory symptoms, and extrapulmonary symptoms according to age group. In total, 203 patients (113, younger; 51, middle-aged; and 39, older) were eligible for the analysis. The maxi-mum body temperature and temperature at first physician visit in the older group were significantly lower than those in the younger group. The incidence of respiratory symptoms was not different among the three groups. Chills, muscle pain, and arthralgia as systemic symptoms were noted significantly more frequently in the younger (80.9%) and middle-aged (75.5%) groups than in the older group (51.3%) (p = 0.002). Fever and sys-temic symptoms were less likely to appear in older patients, possibly resulting in the delaying of hospital visits among older adults.
Keywords influenza, elderly fever respiratory symptom
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2021-10
Volume volume75
Issue issue5
Publisher Okayama University Medical School
Start Page 567
End Page 574
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 34703039
Web of Science KeyUT 000711561600003
NAID 120007166669