result 1175 件
| FullText URL | K0006865_abstract_review.pdf K0006865_summary.pdf K0006865_fulltext.pdf |
|---|---|
| Author | DAI, QI| |
| Published Date | 2023-03-24 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6865号 |
| Granted Date | 2023-03-24 |
| Thesis Type | Doctor of Philosophy |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006806_abstract_review.pdf K0006806_fulltext.pdf K0006806_summary.pdf |
|---|---|
| Author | OKADA, Tomoaki| |
| Published Date | 2023-03-24 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6806号 |
| Granted Date | 2023-03-24 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2022 by the authors. |
| FullText URL | fulltext20230515-03.pdf |
|---|---|
| Author | Hiramoto, Ayami| Baba, Masaaki| Enomoto, Katsunari| Iwakuni, Kana| Kuma, Susumu| Takahashi, Yuiki| Tobaru, Reo| Miyamoto, Yuki| |
| Published Date | 2023-04-13 |
| Publication Title | Physical Review A |
| Volume | volume107 |
| Issue | issue4 |
| Publisher | American Physical Society (APS) |
| Start Page | 043114 |
| ISSN | 2469-9926 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | ©2023 American Physical Society |
| File Version | publisher |
| DOI | 10.1103/physreva.107.043114 |
| Web of Science KeyUT | 000973450100006 |
| Related Url | isVersionOf https://doi.org/10.1103/PhysRevA.107.043114 |
| Title Alternative | The 2021 Incentive Award of the Okayama Medical Association in Cancer Research (2021 Hayashibara Prize and Yamada Prize) |
|---|---|
| FullText URL | 135_9.pdf |
| Author | Yamasaki, Yasushi| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2023-04-01 |
| Volume | volume135 |
| Issue | issue1 |
| Start Page | 9 |
| End Page | 11 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.135.9 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2023 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.135.9 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Otsuka, Yuki| Hagiya, Hideharu| Takahashi, Misa| Fukushima, Shinnosuke| Maeda, Ruri| Sunada, Naruhiko| Yamada, Haruto| Kishida, Masayuki| Fujita, Koji| Otsuka, Fumio| |
| Published Date | 2023-01-12 |
| Publication Title | Scientific Reports |
| Volume | volume13 |
| Issue | issue1 |
| Publisher | Nature Research |
| Start Page | 647 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 36635328 |
| DOI | 10.1038/s41598-022-27330-4 |
| Web of Science KeyUT | 000962604100025 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-022-27330-4 |
| Title Alternative | Clusters of coronavirus disease 2019 in medical institutions and elderly care facilities in Okayama Prefecture |
|---|---|
| FullText URL | 134_86.pdf |
| Author | Kadowaki, Tomoka| Irie, Saori| Takahashi, Yukari| Yakushiji, Hiromasa| Takao, Soshi| Yorifuji, Takashi| |
| Abstract | Coronavirus disease 2019 has spread worldwide and has yet to be contained. The Japanese government has taken measures against the occurrence of clusters. However, there has little evaluation of the occurrence of the clusters and their changes. Therefore, we investigated the occurrence of the clusters in medical institutions and elderly care facilities in Okayama Prefecture. We compared the characteristics of the clusters that occurred in each of the wave between October 21, 2020, and September 30, 2021, by using the data published that interval. As a case study, we also evaluated the characteristics of positive patients at a medical institution over where a cluster occurred in case the fourth wave. The overall number of cluster outbreaks decreased with the spread of vaccination. In the fourth wave, there was a period in which the vaccination of staff members at medical institutions became widespread, while patients or facility users were unvaccinated, resulting in a longer convergence period and an increase in the number of positive cases among patients relative to the number of staff members. The impact of the spread of vaccination and the duration of immunity acquired after vaccination on the occurrence of clusters should be closely monitored in the future. |
| Keywords | 新型コロナウイルス感染症 (coronavirus disease 2019) 岡山県 (Okayama Prefecture) クラスター (cluster) ワクチン接種 (vaccination) 疫学 (epidemiology) |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2022-08-01 |
| Volume | volume134 |
| Issue | issue2 |
| Start Page | 86 |
| End Page | 91 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.134.86 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2022 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.134.86 |
| JaLCDOI | 10.18926/AMO/65155 |
|---|---|
| FullText URL | 77_2_227.pdf |
| Author | Obayashi, Atsuto| Aoki, Kazuma| Wada, Tadayoshi| Furuie, Hiromi | Kuraoka, Kazuya| Hamamoto, Takao| Tatsukawa, Takaharu| |
| Abstract | We describe the use of the tyrosine kinase inhibitor lenvatinib in a patient with brain tumor metastases from anaplastic thyroid carcinoma (ATC). A 52-year-old Japanese male presented with consciousness loss. Imaging revealed a thyroid tumor and multiple brain lesions. After the brain tumor’s resection, pathology results provided the diagnosis of ATC. Total thyroidectomy was performed, followed by whole-brain irradiation. Additional brain lesions later developed, and lenvatinib therapy was initiated with no remarkable complications. However, the treatment effects were limited, and the patient died 2 months after starting lenvatinib, 202 days after the initial brain surgery. Relevant literature is discussed. |
| Keywords | anaplastic thyroid carcinoma brain metastasis lenvatinib |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-04 |
| Volume | volume77 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 227 |
| End Page | 232 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37094963 |
| Web of Science KeyUT | 000982563800006 |
| JaLCDOI | 10.18926/AMO/65154 |
|---|---|
| FullText URL | 77_2_221.pdf |
| Author | Iriyoshi, Hiroki| Sada, Ken-ei| Miyauchi, Atsushi| Yamamoto, Hirotaka| Hashimoto, Daisuke| Nojima, Shigeru| Yamanaka, Shingo| Kawamura, Masafumi| Oka, Satoshi| |
| Abstract | Several previous case reports have shown that patients with immunoglobulin D (IgD) multiple myeloma (MM) can be withdrawn from hemodialysis, however, the characteristics that can predict withdrawal in these patients have not yet been elucidated. A 57-year-old Japanese woman required hemodialysis because of renal dysfunction due to IgD-λ and Bence Jones protein-λ MM. Bortezomib-based chemotherapy nine days after admission led to her withdrawal from hemodialysis on Day 50. In our case-based review, younger age and early initiation of bortezomib-based chemotherapy emerged as possible predictors of successful hemodialysis withdrawal. |
| Keywords | IgD-type multiple myeloma acute renal dysfunction urinary protein hemodialysis bortezomib |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-04 |
| Volume | volume77 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 221 |
| End Page | 225 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37094962 |
| Web of Science KeyUT | 000982563800005 |
| JaLCDOI | 10.18926/AMO/65149 |
|---|---|
| FullText URL | 77_2_193.pdf |
| Author | Ikeda, Tomohiro| Noma, Kazuhiro| Okura, Kazuki| Katayama, Sho| Takahashi, Yusuke| Maeda, Naoaki| Tanabe, Shunsuke| Wakita, Akiyuki| Hamada, Masanori| Fujiwara, Toshiyoshi| Senda, Masuo| |
| Abstract | This retrospective study aimed to investigate the validity of a 30-sec chair stand test (CS-30) as a simple test to assess exercise tolerance and clinical outcomes in 53 Japanese patients with esophageal cancer. There was a strong correlation between the results of CS-30 and the 6-min walk test (6MWT), the gold standard for assessing exercise tolerance (r=0.759). Furthermore, fewer patients whose CS-30 score was greater than 16 (the cutoff value defined based on 6MWT) experienced pneumonia in their postoperative course. These results suggest that exercise tolerance could be assessed using CS-30, and its cutoff value may be useful in predicting postoperative pneumonia risk. |
| Keywords | esophageal cancer exercise tolerance rehabilitation |
| Amo Type | Short Communication |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-04 |
| Volume | volume77 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 193 |
| End Page | 197 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37094957 |
| Web of Science KeyUT | 000982503800009 |
| JaLCDOI | 10.18926/AMO/65148 |
|---|---|
| FullText URL | 77_2_185.pdf |
| Author | Sugihara, Akiko| Okada, Ayumi| Horiuchi, Makiko| Yabe, Mayumi| Shigeyasu, Yoshie| Fujii, Chikako| Tanaka, Chie| Yorifuji, Takashi| Tsukahara, Hirokazu| |
| Abstract | Psychosomatic disorders are influenced by psychosocial factors such as interpersonal relationships. Coping behaviors, especially in frustrating situations, reflect a patient’s ability to cope with stress, and it is important to assess these behaviors for the treatment of psychosomatic diseases. This study aimed to clarify the interpersonal relationships and coping behaviors of pediatric patients with psychosomatic diseases during frustrating situations simulated using the Rosenzweig Picture-Frustration study. This retrospective study included 126 patients (41 male, 85 female) with an average age of 12.9 (6-16) years who were consulted at the Department of Pediatric Psychosomatic Medicine at Okayama University Hospital from 2013 to 2018 and underwent the P-F study. Each score was compared with a standardization sample. The mean group conformity rating did not differ significantly between the participants and healthy children. Compared with healthy children, those with psychosomatic diseases were less likely to explain their perspective. The children with psychosomatic disorders responded to frustrating situations in a sensible and age-appropriate manner. However, they were less likely to respond by explaining their perspective to protect themselves. |
| Keywords | psychosomatic disorder picture-frustration study children projective technique group conformity rating |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-04 |
| Volume | volume77 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 185 |
| End Page | 192 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37094956 |
| Web of Science KeyUT | 000982503800008 |
| JaLCDOI | 10.18926/CTED/65082 |
|---|---|
| Title Alternative | Diverse Learning of Children that Can Be Observed during Developing Play with Flowers in the Class of Kindergarten for Four-year-old Children |
| FullText URL | cted_013_327.pdf |
| Author | Yokota, Saki| NISHIMURA (NAKAGAWA), Kana| Takahashi, Toshiyuki| |
| Abstract | 本論の目的は，幼児教育における遊びの展開を捕捉することである。幼児期の学びは，多様且つ総合的で，全体像の捕捉は困難であり，これまで経験的に理解されてきた。そこで，幼稚園４歳児学級における草花を使った遊びを考察した。遊びの展開に伴って学びは，深化・発展し，保育内容５領域に関係した。偶発的に見える幼児期の学びの背景には，教師の効果的な働きかけがある。 |
| Keywords | 幼児の多様な学び (diverse learning of children) 遊びの展開 (development of play) 幼稚園４歳児学級 (the class of kindergarten for four-year-old children) 草花遊び (play with flowers) |
| Publication Title | Bulletin of Center for Teacher Education and Development, Okayama University |
| Published Date | 2023-03-30 |
| Volume | volume13 |
| Start Page | 327 |
| End Page | 339 |
| ISSN | 2186-1323 |
| language | Japanese |
| Copyright Holders | Copyright © 2023 岡山大学教師教育開発センター |
| File Version | publisher |
| FullText URL | fulltext20230322-2.pdf |
|---|---|
| Author | Takahashi, Masakuni| Sakuma, Ryo| Hashimoto, Hideki| Fujii, Tatsuo| Takada, Jun| |
| Note | This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Physical Chemistry C, copyright © 2023 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.jpcc.2c08380| This full-text file will be available in Jan. 2024.| |
| Published Date | 2023-01-24 |
| Publication Title | The Journal of Physical Chemistry C |
| Volume | volume127 |
| Issue | issue5 |
| Publisher | American Chemical Society (ACS) |
| Start Page | 2223 |
| End Page | 2230 |
| ISSN | 1932-7447 |
| NCID | AA1217589X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 American Chemical Society |
| File Version | author |
| DOI | 10.1021/acs.jpcc.2c08380 |
| Web of Science KeyUT | 000930697400001 |
| Related Url | isVersionOf https://doi.org/10.1021/acs.jpcc.2c08380 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuoka-Uchiyama, Natsumi| Tsuji, Kenji| Takahashi, Kensaku| Fukushima, Kazuhiko| Takeuchi, Hidemi| Kitamura, Shinji| Inagaki, Kenichi| Uchida, Haruhito A. A.| Wada, Jun| |
| Keywords | hypothyroidism kidney function urinary creatinine excretion |
| Published Date | 2023-02-10 |
| Publication Title | Diagnostics |
| Volume | volume13 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 669 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 36832157 |
| DOI | 10.3390/diagnostics13040669 |
| Web of Science KeyUT | 000939117200001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics13040669 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mitoma, Tomohiro| Maki, Jota| Ooba, Hikaru| Eto, Eriko| Takahashi, Kasumi| Kondo, Tsunemasa| Ikeda, Tomohiro| Sakamoto, Yoko| Mitsuhashi, Toshiharu| Masuyama, Hisashi| |
| Keywords | Oestrogen replacement therapy Knee osteoarthritis Muscle resistance exercise Sarcopenia Physical performance |
| Published Date | 2023-02-18 |
| Publication Title | BMC Geriatrics |
| Volume | volume23 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 104 |
| ISSN | 1471-2318 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 36800940 |
| DOI | 10.1186/s12877-023-03828-y |
| Web of Science KeyUT | 000936860000001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12877-023-03828-y |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kawano, Seiji| Oka, Shiro| Shiotani, Akiko| Hashimoto, Shinichi| Takahashi, Sakuma| Handa, Osamu| Takami, Taro| Inaba, Tomoki| Okada, Hiroyuki| Tanaka, Shinji| |
| Keywords | capsule endoscopy Crohn's disease upper small intestine young patients |
| Published Date | 2022-12-16 |
| Publication Title | Medicine |
| Volume | volume101 |
| Issue | issue50 |
| Publisher | Lippincott, Williams & Wilkins |
| Start Page | e32424 |
| ISSN | 0025-7974 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 the Author(s). |
| File Version | publisher |
| PubMed ID | 36550892 |
| DOI | 10.1097/MD.0000000000032424 |
| Web of Science KeyUT | 000921335500100 |
| Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000032424 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Okada, Horoyuki| |
| Keywords | carcinogenesis lymphocytes helicobacter pylori gastric adenocarcinoma flow cytometry |
| Published Date | 2022-11-20 |
| Publication Title | Cureus Journal Of Medical Science |
| Volume | volume14 |
| Issue | issue11 |
| Publisher | Cureus Inc. |
| Start Page | e31713 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Iwamuro et al. |
| File Version | publisher |
| PubMed ID | 36569708 |
| DOI | 10.7759/cureus.31713 |
| Web of Science KeyUT | 000918257500029 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.31713 |
| JaLCDOI | 10.18926/AMO/64371 |
|---|---|
| FullText URL | 77_1_111.pdf |
| Author | Amano, Katsuhiko| Sugauchi, Akinari| Yamada, Chiaki| Kogo, Mikihiko| Iida, Seiji| |
| Abstract | Medication-related osteonecrosis of the jaw (MRONJ) is a side effect in patients taking bone-modifying agents (BMAs), which are highly beneficial for treating osteoporosis and cancer. Bisphosphonates are prescribed to treat secondary osteoporosis in patients with rheumatoid arthritis (RA). We recently encountered two unusual cases of intraoral ONJ in RA patients who had not been treated with a BMA and did not have features of methotrexate- associated lymphoproliferative disorder. Their ONJ stage II bone exposures were treated by conservative therapy, providing good prognoses. These cases indicate that ONJ can occur in RA patients not treated with bisphosphonates. Several risk factors are discussed. |
| Keywords | osteonecrosis of the jaw rheumatoid arthritis risk factor bisphosphonate |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-02 |
| Volume | volume77 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 111 |
| End Page | 116 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36849155 |
| Web of Science KeyUT | 000953005500002 |
| JaLCDOI | 10.18926/AMO/64369 |
|---|---|
| FullText URL | 77_1_97.pdf |
| Author | Hoshijima, Mitsuhiro| Oka, Naoki| Matsumura, Tatsushi| Iida, Seiji| Kamioka, Hiroshi| |
| Abstract | Appropriate operations in severe anterior open bite (AOB) cases are extremely complicated to perform because of the multiple surgical procedures involved, the difficulty of predicting posttreatment aesthetics, and the high relapse rate. We herein report a 16-year-old girl with skeletal Class II, severe AOB malocclusion, and crowding with short roots, and aesthetic and functional problems. Four-piece segmental Le Fort I osteotomy with horseshoe osteotomy was performed for maxillary intrusion, and bilateral sagittal split ramus osteotomy (SSRO) and genioplasty were performed for mandibular advancement. The malocclusion and skeletal deformity were significantly improved by the surgical orthodontic treatment. Functional and aesthetic occlusion with an improved facial profile was established, and no further root shortening was observed. Acceptable occlusion and dentition were maintained after a two-year retention period. This strategy of surgical orthodontic treatment with a complicated operative procedure might be effective for correcting certain severe AOB malocclusion cases. |
| Keywords | anterior open bite short roots severe crowding four-piece segmental horseshoe Le Fort I osteotomy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-02 |
| Volume | volume77 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 97 |
| End Page | 104 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36849153 |
| Web of Science KeyUT | 000952978000003 |
| JaLCDOI | 10.18926/AMO/64368 |
|---|---|
| FullText URL | 77_1_91.pdf |
| Author | Takahashi, Toshiaki| Kakiuchi, Yoshihiko| Kikuch, Satoru| Kuroda, Shinji| Takeda, Sho| Shigeyasu, Kunitoshi| Kondo, Yoshitaka| Teraishi, Fuminori| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Abstract | An annular pancreas is a rare anomaly of the pancreas, defined as pancreatic tissue that totally or partly encircles the duodenum, usually the descending portion. A 76-year-old man who was diagnosed with gastric cancer cT3N0M0 Stage IIB underwent laparoscopic distal gastrectomy with D2 lymph node dissection. Intraoperatively, the dorsal half of the duodenal bulb was seen to be half surrounded by the pancreas, and a non-typical annular pancreas was diagnosed. Because of the risk to the pancreas, it was considered impossible to perform anastomosis by a linear stapler as in the usual laparoscopic procedure. Therefore, we performed laparoscopically assisted distal gastrectomy and Billroth-I reconstruction using a circular stapler, and the surgery was completed without difficulties. His postoperative course was good despite the development of a pancreatic fistula, which was an International Study Group for Pancreas Fistula biochemical leak. Some APs can be diagnosed preoperatively, but the rarer subtypes such as ours are more difficult to visualize on imaging. In gastrectomy, it is both oncologically important and technically challenging to perform lymph node dissection around the pancreas. In this case with an especially proximal pancreas, a circular stapler was considered better suited for gastroduodenal anastomosis and required a broader field than that afforded by laparoscopy. A case of non-typical annular pancreas diagnosed during laparoscopic gastric surgery is described. |
| Keywords | annular pancreas gastric cancer laparoscopic distal gastrectomye |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-02 |
| Volume | volume77 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 91 |
| End Page | 95 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36849152 |
| Web of Science KeyUT | 000952978000002 |
| JaLCDOI | 10.18926/AMO/64367 |
|---|---|
| FullText URL | 77_1_85.pdf |
| Author | Matsuda, Yuki| Otani, Yoshihiro| Yasuhara, Takao| Ando, Mizuo| Higaki, Takaya| Makino, Takuma| Matsumoto, Hiroshi| Oyama, Tadashi| Nishimori, Hisakazu| Date, Isao| |
| Abstract | A 35-year-old female presented with headache, photophobia and developed sudden loss of vision after having undergone right-side ophthalmectomy and radiochemotherapy for retinoblastoma in infancy. A neoplastic lesion was found in the left middle cranial fossa and was surgically removed. The diagnosis was radiation-induced osteosarcoma with RB1 gene alteration. Although she received chemotherapy for the residual tumor, it progressed 17 months later. Maximal surgical resection with craniofacial reconstruction was required. We utilized two three-dimensional models for surgical planning. She was discharged without neurological deficits other than loss of light perception subsequent to left ophthalmectomy. In cases where retinoblastoma is treated with radiotherapy, long-term follow-up is necessary to monitor for radiation-induced tumor development. |
| Keywords | bone model skull base surgery radiation-induced osteosarcoma RB1 gene alteration |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-02 |
| Volume | volume77 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 85 |
| End Page | 90 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36849151 |
| Web of Science KeyUT | 000952978000001 |
