start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue= article-no= start-page=31 end-page=42 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=202503 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Incidence, Management, and Prevention of Gynecomastia and Breast Pain in Patients with Prostate Cancer Undergoing Antiandrogen Therapy: A Systematic Review and Meta-analysis of Randomized Controlled Trials en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background and objective: In patients with prostate cancer treated with antiandrogen monotherapy, gynecomastia and breast pain are relatively common. In the setting of androgen receptor pathway inhibitors (ARPIs), the incidence of these adverse events (AEs) remains unclear. In addition, the effect of prophylactic treatment on gynecomastia remains uncertain. We aimed to evaluate the incidence of gynecomastia and breast pain in prostate cancer patients treated with ARPIs compared with androgen deprivation therapy (ADT) and the effect of prophylactic treatment for these AEs due to antiandrogen therapy.
Methods: In June 2024, we queried four databases?PubMed, Scopus, Web of Science, and Embase?for randomized controlled trials (RCTs) investigating prostate cancer treatments involving antiandrogen therapy. The endpoints of interest were the incidence of these AEs due to ARPIs and the effect of prophylactic treatment for these.
Key findings and limitations: Eighteen RCTs, comprising 5036 patients, were included in the systematic review and meta-analysis. ARPIs included enzalutamide, darolutamide, and apalutamide. The results indicated that patients who received ARPI monotherapy had a significantly higher incidence of gynecomastia than those who received ADT monotherapy (risk ratio [RR]: 5.19, 95% confidence interval [CI]: 3.58?7.51, p < 0.001). There was no significant difference in the incidence of gynecomastia between ARPI plus ADT therapy and ADT monotherapy (RR: 1.27, 95% CI: 0.84?1.93, p = 0.2). Prophylactic tamoxifen or radiotherapy reduced significantly the incidence of gynecomastia and breast pain caused by bicalutamide monotherapy.
Conclusions and clinical implications: We found that ARPI monotherapy increases the incidence of these AEs significantly compared with ADT. In contrast, ARPI plus ADT therapy did not result in a higher incidence of AEs. The use of either tamoxifen or radiotherapy was effective in reducing the incidence of these AEs due to bicalutamide monotherapy. These prophylactic treatments could reduce the incidence of AEs due to ARPI monotherapy. However, further studies are needed to clarify their efficacy.
Patient summary: Although androgen deprivation therapy (ADT) improves overall survival in patients with prostate cancer, it is associated with several complications. Androgen receptor pathway inhibitor (ARPI) monotherapy has emerged as a promising strategy for improving oncological outcomes in these patients. However, ARPI monotherapy increases gynecomastia and breast pain in prostate cancer patients compared with ADT, while ARPI plus ADT did not result in a higher incidence of adverse events. en-copyright= kn-copyright= en-aut-name=TsuboiIchiro en-aut-sei=Tsuboi en-aut-mei=Ichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SchulzRobert J. en-aut-sei=Schulz en-aut-mei=Robert J. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=LaukhtinaEkaterina en-aut-sei=Laukhtina en-aut-mei=Ekaterina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=WadaKoichiro en-aut-sei=Wada en-aut-mei=Koichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KarakiewiczPierre I. en-aut-sei=Karakiewicz en-aut-mei=Pierre I. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ArakiMotoo en-aut-sei=Araki en-aut-mei=Motoo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ShariatShahrokh F. en-aut-sei=Shariat en-aut-mei=Shahrokh F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=3 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=4 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=5 en-affil=Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre kn-affil= affil-num=6 en-affil=Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= en-keyword=Antiandrogen therapy kn-keyword=Antiandrogen therapy en-keyword=Androgen deprivation therapy kn-keyword=Androgen deprivation therapy en-keyword=Androgen receptor pathway inhibitors kn-keyword=Androgen receptor pathway inhibitors en-keyword=Breast pain kn-keyword=Breast pain en-keyword=Gynecomastia kn-keyword=Gynecomastia END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=107 end-page=119 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Investigation Towards Detecting Landing Websites for?Fake Japanese Shopping Websites en-subtitle= kn-subtitle= en-abstract= kn-abstract=Recently, the number of victims of fake shopping websites that imitate legitimate ones to defraud people has been increasing. It has been shown that fake shopping websites use legitimate defaced landing websites as their leading paths. Therefore, if the detection of landing websites for fake shopping websites can be achieved, it can assist in addressing these websites and reduce the opportunities for users to be redirected to fake shopping websites. In this study, we collect and investigate existing landing websites that redirect users to fake Japanese shopping websites and identify effective features for detecting them. We identified effective search terms for collecting landing websites for fake Japanese shopping websites and found that using Google searches with queries of top-level domain and product names was effective. We also investigated the conditions for activating analytical evasion functions in the collected landing websites for fake Japanese shopping websites and clarified the differences in search results between crawlers and users. en-copyright= kn-copyright= en-aut-name=MichishitaDaigo en-aut-sei=Michishita en-aut-mei=Daigo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KobayashiSatoru en-aut-sei=Kobayashi en-aut-mei=Satoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Dockerイメージ生成およびFlutterプログラミング演習問題解答のためのWebアプリケーションシステムの実装 kn-title=Implementations of Web Application Systems for Docker Image Generation and Flutter Programming Exercise Answer en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=LYNN HTET AUNG en-aut-sei=LYNN HTET AUNG en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama university kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=13 cd-vols= no-issue=4 article-no= start-page=139 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250402 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=An Implementation of Creep Test Assisting System with Dial Gauge Needle Reading and Smart Lighting Function for Laboratory Automation en-subtitle= kn-subtitle= en-abstract= kn-abstract=For decades, analog dial gauges have been essential for measuring and monitoring data at various industrial instruments including production machines and laboratory equipment. Among them, we focus on the instrument for creep test in a mechanical engineering laboratory, which evaluates material strength under sustained stress. Manual reading of gauges imposes significant labor demands, especially in long-duration tests. This burden further increases under low-lighting environments, where poor visibility can lead to misreading data points, potentially compromising the accuracy of test results. In this paper, to address the challenges, we implement a creep test assisting system that possesses the following features: (1) to save the installation cost, a web camera and Raspberry Pi are employed to capture images of the dial gauge and automate the needle reading by image processing in real time, (2) to ensure reliability under low-lighting environments, a smart lighting mechanism is integrated to turn on a supplementary light when the dial gauge is not clearly visible, and (3) to allow a user to stay in a distant place from the instrument during a creep test, material break is detected and the corresponding message is notified to a laboratory staff using LINE automatically. For evaluations, we install the implemented system into a material strength measuring instrument at Okayama University, Japan, and confirm the effectiveness and accuracy through conducting experiments under various lighting conditions. en-copyright= kn-copyright= en-aut-name=KongDezheng en-aut-sei=Kong en-aut-mei=Dezheng kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FangShihao en-aut-sei=Fang en-aut-mei=Shihao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NopriantoMitsuhiro en-aut-sei=Noprianto en-aut-mei=Mitsuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OkayasuMitsuhiro en-aut-sei=Okayasu en-aut-mei=Mitsuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=PuspitaningayuPradini en-aut-sei=Puspitaningayu en-aut-mei=Pradini kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=6 en-affil=Department of Electrical Engineering, Universitas Negeri Surabaya kn-affil= en-keyword=creep test kn-keyword=creep test en-keyword=Raspberry Pi kn-keyword=Raspberry Pi en-keyword=dial gauge kn-keyword=dial gauge en-keyword=needle reading kn-keyword=needle reading en-keyword=smart lighting kn-keyword=smart lighting END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=1 end-page=12 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250314 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relationship between Sexual Minorities and Attention Deficit Hyperactivity Disorder (ADHD) kn-title=セクシュアルマイノリティと発達障害のADHD特性との関連 en-subtitle= kn-subtitle= en-abstract=To reveal the association between various sexual minority groups and the developmental disorder (ADHD), a web-based survey was conducted. Adults aged 18 years and over were surveyed and 11018 people (mean age 39.47 years) responded. The Adult ADHD Self-Rating Scale was used. For each sexual minority, a t-test was performed for ADHD scores and subscale scores of “inattention,” “hyperactivity,” and “impulsivity,” and a x2 test was performed for the number of persons above the cut-off. All sexual minority groups had significantly higher ADHD and subscale scores and significantly more people above the cut-off scores, so the close association was evident. There was no significant difference in ADHD scores or numbers of persons between transwomen and transmen. kn-abstract=　様々なセクシュアルマイノリティと発達障害のADHD（Attention Deficit Hyperactivity Disorder）との関連を明らかにするため， WEB調査を行った。18歳以上の成人を対象とし，11,018人（平均年39.47歳）から回答を得た。ADHDを測る質問紙は「成人期ADHD検査（A-ADHD）」を使用した。セクシュアルマイノリティごとに， ADHD得点と下位尺度「不注意」「多動性」「衝動性」得点についてt検定，カットオフ54点以上の人数についてx2検定を行った。全てのセクシュアルマイノリティで有意にADHDと下位尺度得点が高く，カットオフ得点以上の人数も有意に多かった。なおトランスウーマンとトランスマンでADHD得点や人数に有意な差は見られなかった。以上から，セクシュアルマイノリティとADHDは密接に関係している事が明らかとなった。 en-copyright= kn-copyright= en-aut-name=MATSUIMegumi en-aut-sei=MATSUI en-aut-mei=Megumi kn-aut-name=松井めぐみ kn-aut-sei=松井 kn-aut-mei=めぐみ aut-affil-num=1 ORCID= affil-num=1 en-affil=Institute for Promotion of Education and Campus Life, Okayama University kn-affil=岡山大学教育推進機構 en-keyword=セクシュアルマイノリティ kn-keyword=セクシュアルマイノリティ en-keyword=発達障害 kn-keyword=発達障害 en-keyword=ADHD kn-keyword=ADHD en-keyword=注意欠如・多動症 kn-keyword=注意欠如・多動症 END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=1 article-no= start-page=2 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Enhancing Campus Environment: Real-Time Air Quality Monitoring Through IoT and Web Technologies en-subtitle= kn-subtitle= en-abstract= kn-abstract=Nowadays, enhancing campus environments through mitigations of air pollutions is an essential endeavor to support academic achievements, health, and safety of students and staffs in higher educational institutes. In laboratories, pollutants from welding, auto repairs, or chemical experiments can drastically degrade the air quality in the campus, endangering the respiratory and cognitive health of students and staffs. Besides, in universities in Indonesia, automobile emissions of harmful substances such as carbon monoxide (CO), nitrogen dioxide (NO2), and hydrocarbon (HC) have been a serious problem for a long time. Almost everybody is using a motorbike or a car every day in daily life, while the number of students is continuously increasing. However, people in many campuses including managements do not be aware these problems, since air quality is not monitored. In this paper, we present a real-time air quality monitoring system utilizing Internet of Things (IoT) integrated sensors capable of detecting pollutants and measuring environmental conditions to visualize them. By transmitting data to the SEMAR IoT application server platform via an ESP32 microcontroller, this system provides instant alerts through a web application and Telegram notifications when pollutant levels exceed safe thresholds. For evaluations of the proposed system, we adopted three sensors to measure the levels of CO, NO2, and HC and conducted experiments in three sites, namely, Mechatronics Laboratory, Power and Emission Laboratory, and Parking Lot, at the State Polytechnic of Malang, Indonesia. Then, the results reveal Good, Unhealthy, and Dangerous for them, respectively, among the five categories defined by the Indonesian government. The system highlighted its ability to monitor air quality fluctuations, trigger warnings of hazardous conditions, and inform the campus community. The correlation of the sensor levels can identify the relationship of each pollutant, which provides insight into the characteristics of pollutants in a particular scenario. en-copyright= kn-copyright= en-aut-name=RahmadaniAlfiandi Aulia en-aut-sei=Rahmadani en-aut-mei=Alfiandi Aulia kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SyaifudinYan Watequlis en-aut-sei=Syaifudin en-aut-mei=Yan Watequlis kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SetiawanBudhy en-aut-sei=Setiawan en-aut-mei=Budhy kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=PandumanYohanes Yohanie Fridelin en-aut-sei=Panduman en-aut-mei=Yohanes Yohanie Fridelin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of Electrical Engineering, State Polytechnic of Malang kn-affil= affil-num=2 en-affil=Department of Information Technology, State Polytechnic of Malang kn-affil= affil-num=3 en-affil=Department of Electrical Engineering, State Polytechnic of Malang kn-affil= affil-num=4 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=5 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= en-keyword=Internet of Things kn-keyword=Internet of Things en-keyword= campus air quality kn-keyword= campus air quality en-keyword= pollutant detection kn-keyword= pollutant detection en-keyword= SEMAR kn-keyword= SEMAR en-keyword= sensor technology kn-keyword= sensor technology en-keyword= web application kn-keyword= web application END start-ver=1.4 cd-journal=joma no-vol=13 cd-vols= no-issue=24 article-no= start-page=4878 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241211 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=An Implementation of Web-Based Answer Platform in the Flutter Programming Learning Assistant System Using Docker Compose en-subtitle= kn-subtitle= en-abstract= kn-abstract=Programming has gained significant importance worldwide as societies increasingly rely on computer application systems. To support novices in learning various programming languages, we have developed the Programming Learning Assistant System (PLAS). It offers several types of exercise problems with different learning goals and levels for step-by-step self-study. As a personal answer platform in PLAS, we have implemented a web application using Node.js and EJS for Java and Python programming. Recently, the Flutter framework with Dart programming has become popular, enabling developers to build applications for mobile, web, and desktop environments from a single codebase. Thus, we have extended PLAS by implementing the Flutter environment with Visual Studio Code to support it. Additionally, we have developed an image-based user interface (UI) testing tool to verify student source code by comparing its generated UI image with the standard one using the ORB and SIFT algorithms in OpenCV. For efficient distribution to students, we have generated Docker images of the answer platform, Flutter environment, and image-based UI testing tool. In this paper, we present the implementation of a web-based answer platform for the Flutter Programming Learning Assistant System (FPLAS) by integrating three Docker images using Docker Compose. Additionally, to capture UI images automatically, an Nginx web application server is adopted with its Docker image. For evaluations, we asked 10 graduate students at Okayama University, Japan, to install the answer platform on their PCs and solve five exercise problems. All the students successfully completed the problems, which confirms the validity and effectiveness of the proposed system. en-copyright= kn-copyright= en-aut-name=AungLynn Htet en-aut-sei=Aung en-aut-mei=Lynn Htet kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AungSoe Thandar en-aut-sei=Aung en-aut-mei=Soe Thandar kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KyawHtoo Htoo Sandi en-aut-sei=Kyaw en-aut-mei=Htoo Htoo Sandi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KaoWen-Chung en-aut-sei=Kao en-aut-mei=Wen-Chung kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=2 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=3 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=4 en-affil=Department of Computer and Information Science, Tokyo University of Agriculture and Technology kn-affil= affil-num=5 en-affil=Department of Electrical Engineering, National Taiwan Normal University kn-affil= en-keyword=Flutter kn-keyword=Flutter en-keyword=Dart kn-keyword=Dart en-keyword=answer platform kn-keyword=answer platform en-keyword=Flutter environment kn-keyword=Flutter environment en-keyword=Nginx kn-keyword=Nginx en-keyword=UI testing tool kn-keyword=UI testing tool en-keyword=Docker Compose kn-keyword=Docker Compose END start-ver=1.4 cd-journal=joma no-vol=31 cd-vols= no-issue=2 article-no= start-page=102575 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241203 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Clinical and microbiological characteristics of high-level daptomycin-resistant Corynebacterium species: A systematic scoping review en-subtitle= kn-subtitle= en-abstract= kn-abstract=Introduction: Corynebacterium species potentially develop high-level daptomycin resistance (HLDR) shortly after daptomycin (DAP) administration. We aimed to investigate the clinical and microbiological characteristics of HLDR Corynebacterium infections.
Methods: We first presented a clinical case accompanied by the results of a comprehensive genetic analysis of the isolate, and then performed a systematic scoping review. Based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews, we searched for articles with related keywords, including “Corynebacterium”, “Daptomycin", and "Resistance”, in the MEDLINE and Web of Science databases from the database inception to October 25, 2024. Clinical case reports and research articles documenting the isolation of HLDR Corynebacterium species, defined by a minimum inhibitory concentration of DAP at ?256 μg/mL, were deemed eligible for this review.
Results: Of 80 articles screened, seven case reports detailing eight cases of HLDR Corynebacterium infections, as well as five research articles, were included. C. striatum was the most common species (7/9 cases, 77.8 %), and prosthetic device-associated infections accounted for 66.7 % of the cases. Duration of DAP administration before the emergence of HLDR isolates ranged from 5 days to 3 months; three-quarters of the cases developed within 17 days. Three HLDR isolates were genetically confirmed to have an alteration in pgsA2. The majority of the patients were treated with either glycopeptides or linezolid, with favorable outcomes. In vitro experiments confirmed that C. striatum strains acquire the HLDR phenotype at higher rates (71 %?100 %) within 24 h of incubation, compared to other Corynebacterium strains.
Conclusion: DAP monotherapy, especially for prosthetic device-associated infections, can result in the development of HLDR Corynebacterium. Additional research is warranted to investigate the clinical implications of this potentially proliferating antimicrobial resistant pathogen. en-copyright= kn-copyright= en-aut-name=FukushimaShinnosuke en-aut-sei=Fukushima en-aut-mei=Shinnosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HagiyaHideharu en-aut-sei=Hagiya en-aut-mei=Hideharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=GotohKazuyoshi en-aut-sei=Gotoh en-aut-mei=Kazuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TsujiShuma en-aut-sei=Tsuji en-aut-mei=Shuma kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=IioKoji en-aut-sei=Iio en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=AkazawaHidemasa en-aut-sei=Akazawa en-aut-mei=Hidemasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MatsushitaOsamu en-aut-sei=Matsushita en-aut-mei=Osamu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Bacteriology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Infectious Diseases, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of Medical Laboratory Science, Okayama University Graduate School of Health Sciences kn-affil= affil-num=4 en-affil=Department of Medical Laboratory Science, Okayama University Graduate School of Health Sciences kn-affil= affil-num=5 en-affil=Microbiology Division, Clinical Laboratory, Okayama University Hospital kn-affil= affil-num=6 en-affil=Department of Infectious Diseases, Okayama University Hospital kn-affil= affil-num=7 en-affil=Department of Bacteriology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Infectious Diseases, Okayama University Hospital kn-affil= en-keyword=Antimicrobial resistance kn-keyword=Antimicrobial resistance en-keyword=Corynebacterium kn-keyword=Corynebacterium en-keyword=Daptomycin kn-keyword=Daptomycin en-keyword=High-level daptomycin resistance kn-keyword=High-level daptomycin resistance en-keyword=pgsA2 kn-keyword=pgsA2 END start-ver=1.4 cd-journal=joma no-vol=31 cd-vols= no-issue=2 article-no= start-page=102554 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241105 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Human Papillomavirus vaccination awareness and uptake among healthcare students in Japan en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: The vaccination rate for HPV (Human Papillomavirus) has remained significantly low in Japan because of the administrative suspension of active recommendation. This study investigates the awareness and uptake of the HPV vaccine among healthcare students in Japan following the reinstatement of active recommendation for young women in April 2022.
Methods: A web-based survey was administered to 2567 healthcare students from Okayama and Shujitsu Universities in Japan in July 2023. The survey assessed participants' backgrounds, immunization status, awareness of vaccine recommendations, and knowledge of cervical cancer across various demographics, including sex, academic year, and department (Medicine, Health Science, Pharmaceutical, and Dentistry).
Results: The response rate was 36.3 % (933 students; 181 male, 739 female, and 13 unspecified gender). The overall immunization rate among female students was 55.6 %, with higher rates observed in medical (73.8 %) and dental (63.0 %) students. Awareness of the government's change in vaccine recommendation was notably high among female and senior male students. Over half of the female students (54.7 %) reported receiving vaccinations based on their parents' advice. Among those unvaccinated but interested in future immunization, concerns about adverse reactions (47.4 %) and challenges in scheduling vaccinations (29.1 %) were predominant.
Conclusion: Healthcare students exhibited a higher HPV vaccination rate than the general population. Ongoing education to improve vaccine literacy is crucial for augmenting HPV vaccination rates in Japan. en-copyright= kn-copyright= en-aut-name=ShimbeMadoka en-aut-sei=Shimbe en-aut-mei=Madoka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OtsukaYuki en-aut-sei=Otsuka en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HagiyaHideharu en-aut-sei=Hagiya en-aut-mei=Hideharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamadaYoichi en-aut-sei=Yamada en-aut-mei=Yoichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Infectious Diseases, Okayama University Hospital kn-affil= affil-num=4 en-affil=School of Pharmacy, Shujitsu University kn-affil= affil-num=5 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=Cervical cancer kn-keyword=Cervical cancer en-keyword=Human Papillomavirus kn-keyword=Human Papillomavirus en-keyword=Immunization kn-keyword=Immunization en-keyword=Vaccine literacy kn-keyword=Vaccine literacy END start-ver=1.4 cd-journal=joma no-vol=4 cd-vols= no-issue= article-no= start-page=80 end-page=90 dt-received= dt-revised= dt-accepted= dt-pub-year=2025 dt-pub=20250325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A brief study on the gun-teki sekai (social conditions in the district) of Asuwa district in Echizen province kn-title=古代越前国足羽郡の「郡的世界」寸考 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　Often discussed in recent years, the term gun-teki sekai refers to the social conditions of a district. In ancient Japanese local communities, there existed complex webs of historical rule and intertwined relationships between local clans that date back to before the establishment of the Ritsury? system. Gun-teki sekai is a term that refers to the reality of the control of the provincial and district systems, in which multiple powerful clans served as gunji , district governors under the Ritsury? system. Each gunji organized smaller clans below them to carry out administrative duties based on such relationships. Recent research is beginning to reveal the multipolar structure of the gun-teki sekai .
　In this study, the author examines the gun-teki sekai through an analysis of the Asuwa district in Echizen province, which is rich in historical materials. As a result, the following four points became clear. First, it is highly likely that the powerful clans who served as district governors in the mid-Nara period were traditional clans with roots in the eastern part of the district. Second, the powerful clans who served as district deputy governors may have been an emerging power. Third, from an archaeological perspective, the eastern part of the district is the traditional area, while the dominance of the western part of the district developed after the establishment of the Ritsury? system. Fourth, in terms of clan distribution, the clans who served as district governors were distributed over the widest area, followed by those who served as district deputy governors. en-copyright= kn-copyright= en-aut-name=WATANABEAtsunori en-aut-sei=WATANABE en-aut-mei=Atsunori kn-aut-name=渡部敦寛 kn-aut-sei=渡部 kn-aut-mei=敦寛 aut-affil-num=1 ORCID= affil-num=1 en-affil=Chigasaki City Museum kn-affil= en-keyword=Gun-teki sekai kn-keyword=Gun-teki sekai en-keyword=gunji（district governors under the Ritsury? system) kn-keyword=gunji（district governors under the Ritsury? system) en-keyword=local powerful clans kn-keyword=local powerful clans en-keyword=clan distribution kn-keyword=clan distribution en-keyword=Asuwa district kn-keyword=Asuwa district en-keyword=Echizen province kn-keyword=Echizen province END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue= article-no= start-page=58 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=2023 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Association and dose-response relationship between exposure to alcohol advertising media and current drinking: a nationwide cross-sectional study of Japanese adolescents en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: Underage drinking is a public health concern. However, few studies have examined the association between alcoholic beverage advertising and underage drinking, particularly in countries with low underage drinking rates, such as Japan. Therefore, we aimed to investigate the relationship between exposure to advertising in various media and alcohol drinking among Japanese adolescents.
Methods: We conducted a cross-sectional study involving 15,683 adolescents (51% girls) using data from a nationwide lifestyle survey in 2021 among junior and senior high schools across Japan. Media types were websites, stores, and public transportation. We defined current drinking as alcohol consumption of ?1 day in the 30 days preceding the survey. Multivariable logistic regression was used to examine the association between exposure to alcohol advertisements and current drinking, adjusting for sex, grades, school area, lifestyle (bedtime and having fun at school), and addictive behaviors (smoking status and parents’ alcohol consumption).
Results: The prevalence of current drinking was 2.2% (2.3% of boys and 2.0% of girls). Students who were exposed to any alcohol advertising media had higher odds of current drinking compared with those who were not (odds ratio, 1.48; 95% confidence interval [CI], 1.18?1.87). Students who were exposed to web, in-store, and public transportation advertisements had odds ratios of 1.44 (95% CI, 1.14?1.81), 1.62 (1.28?2.05), and 1.45 (1.06?1.98) of current drinking, respectively, compared with those who were not. The association of exposure to alcohol advertising media with the prevalence of current drinking was similar among boys and girls (all p for sex interaction >0.1), except for that of exposure to web advertisements; its association with current drinking was more pronounced in girls (p for sex interaction = 0.046). Exposure to a larger cumulative number of different alcohol advertising media was independently associated with a higher prevalence of current drinking among all students, boys, and girls (p-values for trend <0.001, 0.031, and <0.001, respectively; p for sex interaction = 0.085).
Conclusions: We found an association with a dose-response relationship between exposure to alcohol advertisements and current drinking among adolescents in junior and senior high schools across Japan. Our findings highlight the need for further advertising regulations to prevent underage drinking. en-copyright= kn-copyright= en-aut-name=YoshidaKeita en-aut-sei=Yoshida en-aut-mei=Keita kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KandaHideyuki en-aut-sei=Kanda en-aut-mei=Hideyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HisamatsuTakashi en-aut-sei=Hisamatsu en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KuwabaraYuki en-aut-sei=Kuwabara en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KinjoAya en-aut-sei=Kinjo en-aut-mei=Aya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=YoshimotoHisashi en-aut-sei=Yoshimoto en-aut-mei=Hisashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ItoTeruna en-aut-sei=Ito en-aut-mei=Teruna kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KasugaHideaki en-aut-sei=Kasuga en-aut-mei=Hideaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=MinobeRuriko en-aut-sei=Minobe en-aut-mei=Ruriko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=MaesatoHitoshi en-aut-sei=Maesato en-aut-mei=Hitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=JikeMaki en-aut-sei=Jike en-aut-mei=Maki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=MatsumotoYuuki en-aut-sei=Matsumoto en-aut-mei=Yuuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=OtsukaYuichiro en-aut-sei=Otsuka en-aut-mei=Yuichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=ItaniOsamu en-aut-sei=Itani en-aut-mei=Osamu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=KaneitaYoshitaka en-aut-sei=Kaneita en-aut-mei=Yoshitaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=HiguchiSusumu en-aut-sei=Higuchi en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= en-aut-name=OsakiYoneatsu en-aut-sei=Osaki en-aut-mei=Yoneatsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=17 ORCID= affil-num=1 en-affil=Department of Public Health, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Public Health, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Public Health, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Division of Environmental and Preventive Medicine, Department of Social Medicine, Faculty of Medicine, Tottori University kn-affil= affil-num=5 en-affil=Division of Environmental and Preventive Medicine, Department of Social Medicine, Faculty of Medicine, Tottori University kn-affil= affil-num=6 en-affil=Department of Family Medicine, General Practice and Community Health, Institute of Medicine, University of Tsukuba kn-affil= affil-num=7 en-affil=Department of Food and Nutrition, Koriyama Women’s University kn-affil= affil-num=8 en-affil=Department of Hygiene and Preventive Medicine, Fukushima Medical University kn-affil= affil-num=9 en-affil=National Institute of Alcoholism, Kurihama National Hospital kn-affil= affil-num=10 en-affil=National Institute of Alcoholism, Kurihama National Hospital kn-affil= affil-num=11 en-affil=Department of Food Science and Nutrition, Faculty of Life and Environmental Science, Showa Women’s University kn-affil= affil-num=12 en-affil=Division of Public Health, Department of Social Medicine, Nihon University School of Medicine kn-affil= affil-num=13 en-affil=Division of Public Health, Department of Social Medicine, Nihon University School of Medicine kn-affil= affil-num=14 en-affil=Division of Public Health, Department of Social Medicine, Nihon University School of Medicine kn-affil= affil-num=15 en-affil=Division of Public Health, Department of Social Medicine, Nihon University School of Medicine kn-affil= affil-num=16 en-affil=National Institute of Alcoholism, Kurihama National Hospital kn-affil= affil-num=17 en-affil=Division of Environmental and Preventive Medicine, Department of Social Medicine, Faculty of Medicine, Tottori University kn-affil= en-keyword=Underage drinking kn-keyword=Underage drinking en-keyword=Alcohol kn-keyword=Alcohol en-keyword=Adolescents kn-keyword=Adolescents en-keyword=Advertisement kn-keyword=Advertisement END start-ver=1.4 cd-journal=joma no-vol=65 cd-vols= no-issue=10 article-no= start-page=1488 end-page=1500 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241015 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Method for Inter-Broadcaster Data Integration of Non-Identifiable Television Viewing Log kn-title=非特定テレビ視聴履歴データの放送局間統合手法 en-subtitle= kn-subtitle= en-abstract=Recently, TV broadcasters have been collecting and utilizing non-personal TV viewing log data, including start and end times of viewing, from TVs connected to the Internet in a format that does not identify individual viewers. However, since each broadcaster can only use its own non-personal TV viewing log data, it has not yet been able to obtain useful knowledge despite the vast amount of data it has accumulated. In addition, the collection methods and data granularity of non-personal TV viewing log data vary from station to station, and the data accumulated by each station cannot be integrated and used. In this paper, we propose a method for matching non-specific viewing history data collected by each broadcaster using its own method, and design and implement a simulator to evaluate the proposed method. The proposed method estimates that TVs whose channel transition timing matches five items collected at the time of viewing history data collection (IP address, zip code, manufacturer ID, browser major version, and browser minor version) are the same TVs. In addition, we designed a simulator that reproduces viewer behavior and applied this method to the viewing history data synthesized from the simulator. As a result, we succeeded in matching approximately 2.41 million TVs out of the 2.5 million units of data generated, showing an identification rate of 96.5%. kn-abstract=近年，各テレビ放送局において，個人を特定しない形式で，インターネット接続されたテレビから視聴開始時刻や視聴終了時刻等を含む非特定視聴履歴データを収集し，利活用する取り組みが進められている．しかし，各放送局は自局の非特定視聴履歴データしか利用できないため，膨大なデータを蓄積しているにもかかわらず，有用な知見を得るまでに至っていないのが現状である．さらに，非特定視聴履歴データの収集方式やデータ粒度は，各局各様となっており，各局が蓄積したデータを統合し，利用することもできていない．そこで本論文では，各局が独自の方式で取得している非特定視聴履歴データを放送局間で統合する手法を提案し，評価するためのシミュレータ設計と実装を行い，提案手法の評価を行う．
提案手法では，各局の視聴履歴データのうち，共通しているIPアドレス・郵便番号・メーカID・ブラウザメジャーバージョン・ブラウザマイナーバージョンの5項目でテレビ受像機を分離処理する．そして，分離された中でこれらの5項目が一致するテレビのうち，さらにチャンネル遷移時刻が一致するテレビを同一テレビと推定する．また，視聴者行動を再現するシミュレータを設計し，そのシミュレータから合成された視聴履歴データに対して，本手法を適用した結果，生成された250万台分のデータのうち約241万台のテレビIDのマッチングに成功し，再現率96.5%であることを示した． en-copyright= kn-copyright= en-aut-name=MatsudaHiroki en-aut-sei=Matsuda en-aut-mei=Hiroki kn-aut-name=松田裕貴 kn-aut-sei=松田 kn-aut-mei=裕貴 aut-affil-num=1 ORCID= en-aut-name=SakakibaraTaichi en-aut-sei=Sakakibara en-aut-mei=Taichi kn-aut-name=榊原太一 kn-aut-sei=榊原 kn-aut-mei=太一 aut-affil-num=2 ORCID= en-aut-name=MayumiDaiki en-aut-sei=Mayumi en-aut-mei=Daiki kn-aut-name=真弓大輝 kn-aut-sei=真弓 kn-aut-mei=大輝 aut-affil-num=3 ORCID= en-aut-name=MatsudaYuki en-aut-sei=Matsuda en-aut-mei=Yuki kn-aut-name=松田裕貴 kn-aut-sei=松田 kn-aut-mei=裕貴 aut-affil-num=4 ORCID= en-aut-name=MizumotoTeruhiro en-aut-sei=Mizumoto en-aut-mei=Teruhiro kn-aut-name=水本旭洋 kn-aut-sei=水本 kn-aut-mei=旭洋 aut-affil-num=5 ORCID= en-aut-name=YasumotoKeiichi en-aut-sei=Yasumoto en-aut-mei=Keiichi kn-aut-name=安本慶一 kn-aut-sei=安本 kn-aut-mei=慶一 aut-affil-num=6 ORCID= affil-num=1 en-affil=Nara Institute of Science and Technology kn-affil=奈良先端科学技術大学院大学 affil-num=2 en-affil=Yomiuri Telecasting Corporation kn-affil=讀賣テレビ放送株式会社 affil-num=3 en-affil=Nara Institute of Science and Technology kn-affil=奈良先端科学技術大学院大学 affil-num=4 en-affil=Okayama University kn-affil=岡山大学 affil-num=5 en-affil=Chiba Institute of Technology kn-affil=千葉工業大学 affil-num=6 en-affil=Nara Institute of Science and Technology kn-affil=奈良先端科学技術大学院大学 en-keyword=テレビ (TV) kn-keyword=テレビ (TV) en-keyword=視聴履歴データ (TV viewing log data) kn-keyword=視聴履歴データ (TV viewing log data) en-keyword=ビッグデータ (Big data) kn-keyword=ビッグデータ (Big data) en-keyword=IoT kn-keyword=IoT en-keyword=クロスデバイスマッチング (Cross-device matching) kn-keyword=クロスデバイスマッチング (Cross-device matching) en-keyword=クロスデバイストラッキング (Cross-device tracking) kn-keyword=クロスデバイストラッキング (Cross-device tracking) END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=10 article-no= start-page=622 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241010 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A Study of Exergame System Using Hand Gestures for Wrist Flexibility Improvement for Tenosynovitis Prevention en-subtitle= kn-subtitle= en-abstract= kn-abstract=Currently, as an increasing number of people have been addicted to using cellular phones, smartphone tenosynovitis has become common from long-term use of fingers for their operations. Hand exercise while playing video games, which is called exergame, can be a good solution to provide enjoyable daily exercise opportunities for its prevention, particularly, for young people. In this paper, we implemented a simple exergame system with a hand gesture recognition program made in Python using the Mediapipe library. We designed three sets of hand gestures to control the key operations to play the games as different exercises useful for tenosynovitis prevention. For evaluations, we prepared five video games running on a web browser and asked 10 students from Okayama and Hiroshima Universities, Japan, to play them and answer 10 questions in the questionnaire. Their playing results and System Usability Scale (SUS) scores confirmed the usability of the proposal, although we improved one gesture set to reduce its complexity. Moreover, by measuring the angles for maximum wrist movements, we found that the wrist flexibility was improved by playing the games, which verifies the effectiveness of the proposal. en-copyright= kn-copyright= en-aut-name=XiaoYanqi en-aut-sei=Xiao en-aut-mei=Yanqi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AnggrainiIrin Tri en-aut-sei=Anggraini en-aut-mei=Irin Tri kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ShihCheng-Liang en-aut-sei=Shih en-aut-mei=Cheng-Liang kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=FanChih-Peng en-aut-sei=Fan en-aut-mei=Chih-Peng kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=2 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=3 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=4 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=5 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= en-keyword=exergame kn-keyword=exergame en-keyword=tenosynovitis kn-keyword=tenosynovitis en-keyword=hand gesture kn-keyword=hand gesture en-keyword=Python kn-keyword=Python en-keyword=Mediapipe kn-keyword=Mediapipe END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue= article-no= start-page=153285 end-page=153294 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=2024 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Detecting Unintended Redirects to Malicious Websites on Android Devices Based on URL-Switching Interval en-subtitle= kn-subtitle= en-abstract= kn-abstract=Website clicks that redirect Android-phone users to malicious websites with fake virus alerts or phishing attacks are increasing exponentially. Although a uniform resource locator (URL) blocklist is considered a suitable countermeasure to such attacks, it is difficult to efficiently identify malicious websites. To the best of our knowledge, no research has focused on detecting attacks that redirect Android-phone users to malicious websites. Therefore, we propose a redirect-detection method that focuses on the URL bar-switching interval of Android-based Google Chrome browser. The proposed method, which can be easily installed as an Android application, uses the Android accessibility service to detect unintended redirects to malicious websites without collecting information about these websites in advance. This paper details the design, implementation, and evaluation results of the proposed application on an actual Android device. We determined the threshold values for the number of times the URL bar switches and the elapsed time to determine redirects to malicious websites for the proposed method. Based on the results, we investigated the causes of false-positive detection of redirects to benign websites and offer solutions on handling them. We also present the threshold values that can minimize the false positive and negative rates, as well as the detection accuracy of the proposed method based on these threshold values. Additionally, we present the evaluations results based on the access logs of actual users participating in the WarpDrive project experiment, which indicate that the proposed method minimizes false positives and successfully detects most redirects to malicious websites. en-copyright= kn-copyright= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OritoRintaro en-aut-sei=Orito en-aut-mei=Rintaro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=EbisuKoji en-aut-sei=Ebisu en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SatoMasaya en-aut-sei=Sato en-aut-mei=Masaya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Faculty of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Faculty of Computer Science and Systems Engineering, Okayama Prefectural University kn-affil= en-keyword=Android kn-keyword=Android en-keyword=accessibility services kn-keyword=accessibility services en-keyword=malicious websites kn-keyword=malicious websites en-keyword=web-based attacks kn-keyword=web-based attacks en-keyword=web security kn-keyword=web security END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=10 article-no= start-page=614 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20241007 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=An Independent Learning System for Flutter Cross-Platform Mobile Programming with Code Modification Problems en-subtitle= kn-subtitle= en-abstract= kn-abstract=Nowadays, with the common use of smartphones in daily lives, mobile applications have become popular around the world, which will lead to a rise in Flutter framework. Developed by Google, Flutter with Dart programming provides a cross-platform development environment to create visually appealing and responsive user interfaces across mobile, web, and desktop platforms using a single codebase. However, due to time and staff limitations, the Flutter/Dart programming course is not included in curricula, even in IT departments in universities. Therefore, independent learning environments for students are essential to meet this growing popularity. Previously, we have developed programming learning assistant system (PLAS) as a web-browser-based self-learning platform for novice students. PLAS offers various types of exercise problems designed to cultivate programming skills step-by-step through a lot of code reading and code writing practices. Among them, one particular type is the code modification problem (CMP), which asks to modify the given source code to satisfy the new specifications. CMP is expected to be solved by novices with little effort if they have knowledge of other programming languages. Thus, PLAS with CMP will be an excellent platform for independent learning. In this paper, we present PLAS with CMP for the independent learning of Flutter/Dart programming. To improve the readability of the source code by students, we provided rich comments on grammar or behaviors. Besides, the code can be downloaded so that students can check and run it on an IDE. For evaluations, we generated 38 CMP instances for basic and multimedia/storage topics in Flutter/Dart programming and assigned them to 21 master students at Okayama University, Japan, who have never studied it. The results confirm the validity of the proposal. en-copyright= kn-copyright= en-aut-name=KinariSafira Adine en-aut-sei=Kinari en-aut-mei=Safira Adine kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AungSoe Thandar en-aut-sei=Aung en-aut-mei=Soe Thandar kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=WaiKhaing Hsu en-aut-sei=Wai en-aut-mei=Khaing Hsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MentariMustika en-aut-sei=Mentari en-aut-mei=Mustika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=PuspitaningayuPradini en-aut-sei=Puspitaningayu en-aut-mei=Pradini kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Environmental, Life, Natural Science and Technology, Okayama University kn-affil= affil-num=6 en-affil=Department of Electrical Engineering, Universitas Negeri Surabaya kn-affil= en-keyword=Flutter kn-keyword=Flutter en-keyword=Dart kn-keyword=Dart en-keyword=cross-platform kn-keyword=cross-platform en-keyword=programming kn-keyword=programming en-keyword=code modification problem kn-keyword=code modification problem en-keyword=PLAS kn-keyword=PLAS en-keyword=independent learning kn-keyword=independent learning END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=8 article-no= start-page=464 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240803 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=An Image-Based User Interface Testing Method for Flutter Programming Learning Assistant System en-subtitle= kn-subtitle= en-abstract= kn-abstract=Flutter has become popular for providing a uniform development environment for user interfaces (UIs) on smart phones, web browsers, and desktop applications. We have developed the Flutter programming learning assistant system (FPLAS) to assist its novice students' self-study. We implemented the Docker-based Flutter environment with Visual Studio Code and three introductory exercise projects. However, the correctness of students' answers is manually checked, although automatic checking is necessary to reduce teachers' workload and provide quick responses to students. This paper presents an image-based user interface (UI) testing method to automate UI testing by the answer code using the Flask framework. This method produces the UI image by running the answer code and compares it with the image made by the model code for the assignment using ORB and SIFT algorithms in the OpenCV library. One notable aspect is the necessity to capture multiple UI screenshots through page transitions by user input actions for the accurate detection of changes in UI elements. For evaluations, we assigned five Flutter exercise projects to fourth-year bachelor and first-year master engineering students at Okayama University, Japan, and applied the proposed method to their answers. The results confirm the effectiveness of the proposal. en-copyright= kn-copyright= en-aut-name=AungSoe Thandar en-aut-sei=Aung en-aut-mei=Soe Thandar kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AungLynn Htet en-aut-sei=Aung en-aut-mei=Lynn Htet kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KinariSafira Adine en-aut-sei=Kinari en-aut-mei=Safira Adine kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=WaiKhaing Hsu en-aut-sei=Wai en-aut-mei=Khaing Hsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MentariMustika en-aut-sei=Mentari en-aut-mei=Mustika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=2 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=3 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=4 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=5 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=6 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= en-keyword=Flutter kn-keyword=Flutter en-keyword=FPLAS kn-keyword=FPLAS en-keyword=testing kn-keyword=testing en-keyword=image kn-keyword=image en-keyword=Flask kn-keyword=Flask en-keyword=OpenCV kn-keyword=OpenCV en-keyword=user interface kn-keyword=user interface END start-ver=1.4 cd-journal=joma no-vol=186 cd-vols= no-issue= article-no= start-page=13 end-page=20 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Career Self-Reliance Orientation and Workplace Retention among Young Workers: Are Career Support Measures a “Double-Edged Sword” ? kn-title=若年就業者におけるキャリア自律の志向性と職場定着― 支援施策は“諸刃の剣”か？ ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　キャリア自律を推進する企業が増えているが，その一方で各種の支援施策が離職や人材流出を招く懸念も指摘されている。本研究では，就業者が抱くキャリア自律の志向性を考慮した分析を行い，キャリア支援施策の活用度と職場定着に関わる心理的変数との関連を検討した。若年就業者255 名のWeb調査への回答の分析から，キャリア支援施策は離職意思の抑制と組織コミットメントの向上という職場定着に有益な効果を持つことが示された。またその効果は，就業者が業界内や専門分野での活躍など広い視野をもつ専門キャリア志向を抱く場合に，より顕著に表れることが示唆された。 en-copyright= kn-copyright= en-aut-name=MISAWARyo en-aut-sei=MISAWA en-aut-mei=Ryo kn-aut-name=三沢良 kn-aut-sei=三沢 kn-aut-mei=良 aut-affil-num=1 ORCID= en-aut-name=KOBAYASHIChinatsu en-aut-sei=KOBAYASHI en-aut-mei=Chinatsu kn-aut-name=小林千夏 kn-aut-sei=小林 kn-aut-mei=千夏 aut-affil-num=2 ORCID= en-aut-name=HASEGAWANaoko en-aut-sei=HASEGAWA en-aut-mei=Naoko kn-aut-name=長谷川尚子 kn-aut-sei=長谷川 kn-aut-mei=尚子 aut-affil-num=3 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Okayama Labor Bureau kn-affil=岡山労働局 affil-num=3 en-affil=Faculty of Human Sciences, Department of Psychology, Bunkyo University kn-affil=文教大学人間科学部心理学科 en-keyword=若年就業者 kn-keyword=若年就業者 en-keyword=キャリア自律 kn-keyword=キャリア自律 en-keyword=キャリア支援施策 kn-keyword=キャリア支援施策 en-keyword=職場定着 kn-keyword=職場定着 END start-ver=1.4 cd-journal=joma no-vol=78 cd-vols= no-issue=4 article-no= start-page=313 end-page=322 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=202408 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Multicenter Remote-Access Simulation of Vaginal Delivery for High-Flexibility Medical Education during the Coronavirus Pandemic en-subtitle= kn-subtitle= en-abstract= kn-abstract=During the coronavirus pandemic, face-to-face simulation education became impossible. Therefore, we aimed to develop remote-access simulation education with a sense of realism through Information and Communication Technology (ICT) using a perinatal whole-body management and delivery simulator. In September 2021, we administered a multi-center simultaneous remote simulation based on our developed model. Ten universities in the Chugoku?Shikoku region were connected via a web-conferencing system to a live broadcast of a virtual vaginal birth in which a fictional hospitalized pregnant woman experienced accelerated labor and gave birth through vacuum delivery for fetal distress. A Video on Demand (VOD) was made beforehand using a new simulator that allowed for a visual understanding of the process of the inter-vaginal examination. We provided a participatory program that enhanced the sense of realism by combining VOD and real-time lectures on each scenario, with two-way communication between participants and trainee doctors using a chat function. Most participants answered “satisfied” or “very satisfied” with the content, level of difficulty, and level of understanding. From November 2021, we have used the videos of all processes in face-to-face classes. Our construction of a high-flexibility education system using remote simulation in the field of obstetrics and gynecology, especially in the vaginal delivery module, is unique, creative, and sustainable. en-copyright= kn-copyright= en-aut-name=EtoEriko en-aut-sei=Eto en-aut-mei=Eriko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MakiJota en-aut-sei=Maki en-aut-mei=Jota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YamashitaNoriyuki en-aut-sei=Yamashita en-aut-mei=Noriyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HasegawaToru en-aut-sei=Hasegawa en-aut-mei=Toru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SuemoriAyano en-aut-sei=Suemori en-aut-mei=Ayano kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NakatoHikari en-aut-sei=Nakato en-aut-mei=Hikari kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ObaHikaru en-aut-sei=Oba en-aut-mei=Hikaru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=MitomaTomohiro en-aut-sei=Mitoma en-aut-mei=Tomohiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=MishimaSakurako en-aut-sei=Mishima en-aut-mei=Sakurako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=KirinoSatoe en-aut-sei=Kirino en-aut-mei=Satoe kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=OhiraAkiko en-aut-sei=Ohira en-aut-mei=Akiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=MasuyamaHisashi en-aut-sei=Masuyama en-aut-mei=Hisashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= affil-num=1 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Center for Education in Medicine and Health Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=10 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=11 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=12 en-affil=Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=remote simulator education kn-keyword=remote simulator education en-keyword=perinatal simulator kn-keyword=perinatal simulator en-keyword=information and communication technology kn-keyword=information and communication technology en-keyword=high-flexibility education kn-keyword=high-flexibility education END start-ver=1.4 cd-journal=joma no-vol=13 cd-vols= no-issue=14 article-no= start-page=2700 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240710 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A Reference Paper Collection System Using Web Scraping en-subtitle= kn-subtitle= en-abstract= kn-abstract=Collecting reference papers from the Internet is one of the most important activities for progressing research and writing papers about their results. Unfortunately, the current process using Google Scholar may not be efficient, since a lot of paper files cannot be accessed directly by the user. Even if they are accessible, their effectiveness needs to be checked manually. In this paper, we propose a reference paper collection system using web scraping to automate paper collections from websites. This system can collect or monitor data from the Internet, which is considered as the environment, using Selenium, a popular web scraping software, as the sensor; this examines the similarity against the search target by comparing the keywords using the Bert model. The Bert model is a deep learning model for natural language processing (NLP) that can understand context by analyzing the relationships between words in a sentence bidirectionally. The Python Flask is adopted at the web application server, where Angular is used for data presentations. For the evaluation, we measured the performance, investigated the accuracy, and asked members of our laboratory to use the proposed method and provide their feedback. Their results confirm the method’s effectiveness. en-copyright= kn-copyright= en-aut-name=NaingInzali en-aut-sei=Naing en-aut-mei=Inzali kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AungSoe Thandar en-aut-sei=Aung en-aut-mei=Soe Thandar kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=WaiKhaing Hsu en-aut-sei=Wai en-aut-mei=Khaing Hsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=2 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=3 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=4 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= en-keyword=web scraping kn-keyword=web scraping en-keyword=Google Scholar kn-keyword=Google Scholar en-keyword=data collection kn-keyword=data collection en-keyword=Bert kn-keyword=Bert en-keyword=Selenium kn-keyword=Selenium en-keyword=flask framework kn-keyword=flask framework en-keyword=Angular kn-keyword=Angular END start-ver=1.4 cd-journal=joma no-vol=78 cd-vols= no-issue=3 article-no= start-page=205 end-page=213 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=202406 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Thoughts on and Proposal for the Education, Training, and Recruitment of Infectious Disease Specialists en-subtitle= kn-subtitle= en-abstract= kn-abstract=The global pandemic of COVID-19 has underscored the significance of establishing and sustaining a practical and efficient infection control system for the benefit and welfare of society. Infectious disease (ID) specialists are expected to take on leadership roles in enhancing organizational infrastructures for infection prevention and control (IPC) at the hospital, community, and national levels. However, due to an absolute shortage and an uneven distribution, many core hospitals currently lack the ID specialists. Given the escalating global risk of emerging and re-emerging infectious diseases as well as antimicrobial resistance pathogens, the education and training of ID specialists constitutes an imperative concern. As demonstrated by historical changes in the healthcare reimbursement system, the establishment and enhancement of IPC measures is pivotal to ensuring medical safety. The existing structure of academic society-driven certification and training initiatives for ID specialists, contingent upon the discretionary decisions of individual physicians, possesses both quantitative and qualitative shortcomings. In this article, I first address the present situations and challenges related to ID specialists and then introduce my idea of securing ID specialists based on the new concepts and platforms; (i) ID Specialists as National Credentials, (ii) Establishment of the Department of Infectious Diseases in Medical and Graduate Schools, (iii) Endowed ID Educative Courses Funded by Local Government and Pharmaceutical Companies, and (iv) Recruitment of Young Physicians Engaged in Healthcare Services in Remote Areas. As clarified by the COVID-19 pandemic, ID specialists play a crucial role in safeguarding public health. Hopefully, this article will advance the discussion and organizational reform for the education and training of ID specialists. en-copyright= kn-copyright= en-aut-name=HagiyaHideharu en-aut-sei=Hagiya en-aut-mei=Hideharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Infectious Diseases, Okayama University Hospital kn-affil= en-keyword=antimicrobial resistance kn-keyword=antimicrobial resistance en-keyword=emerging infectious diseases kn-keyword=emerging infectious diseases en-keyword=infection prevention and control kn-keyword=infection prevention and control en-keyword=medical education kn-keyword=medical education en-keyword=silent pandemic kn-keyword=silent pandemic END start-ver=1.4 cd-journal=joma no-vol=19 cd-vols= no-issue=5 article-no= start-page=e0302537 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240521 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=The use of artificial intelligence in induced pluripotent stem cell-based technology over 10-year period: A systematic scoping review en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background
Stem cell research, particularly in the domain of induced pluripotent stem cell (iPSC) technology, has shown significant progress. The integration of artificial intelligence (AI), especially machine learning (ML) and deep learning (DL), has played a pivotal role in refining iPSC classification, monitoring cell functionality, and conducting genetic analysis. These enhancements are broadening the applications of iPSC technology in disease modelling, drug screening, and regenerative medicine. This review aims to explore the role of AI in the advancement of iPSC research.
Methods
In December 2023, data were collected from three electronic databases (PubMed, Web of Science, and Science Direct) to investigate the application of AI technology in iPSC processing.
Results
This systematic scoping review encompassed 79 studies that met the inclusion criteria. The number of research studies in this area has increased over time, with the United States emerging as a leading contributor in this field. AI technologies have been diversely applied in iPSC technology, encompassing the classification of cell types, assessment of disease-specific phenotypes in iPSC-derived cells, and the facilitation of drug screening using iPSC. The precision of AI methodologies has improved significantly in recent years, creating a foundation for future advancements in iPSC-based technologies.
Conclusions
Our review offers insights into the role of AI in regenerative and personalized medicine, highlighting both challenges and opportunities. Although still in its early stages, AI technologies show significant promise in advancing our understanding of disease progression and development, paving the way for future clinical applications. en-copyright= kn-copyright= en-aut-name=VoQuan Duy en-aut-sei=Vo en-aut-mei=Quan Duy kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SaitoYukihiro en-aut-sei=Saito en-aut-mei=Yukihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IdaToshihiro en-aut-sei=Ida en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NakamuraKazufumi en-aut-sei=Nakamura en-aut-mei=Kazufumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YuasaShinsuke en-aut-sei=Yuasa en-aut-mei=Shinsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Faculty of Medicine, Department of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Cardiovascular Medicine, Okayama University Hospital kn-affil= affil-num=3 en-affil=Faculty of Medicine, Department of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Faculty of Medicine, Department of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Faculty of Medicine, Department of Cardiovascular Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=4 article-no= start-page=191 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A Study of Learning Environment for Initiating Flutter App Development Using Docker en-subtitle= kn-subtitle= en-abstract= kn-abstract=The Flutter framework with Dart programming allows developers to effortlessly build applications for both web and mobile from a single codebase. It enables efficient conversions to native codes for mobile apps and optimized JavaScript for web browsers. Since utilizing a wide range of widgets in Flutter ensures consistent experiences on various devices for users, it becomes crucial in programming education by providing a unified environment for learning app development while reducing the need for platform-specific knowledge. However, the setup of the Flutter environment is challenging for novice students due to its multiple steps, such as installing dependencies and configuring environments. To support independent learning for these students, it is essential to simplify the setup by providing user-friendly instructions and automated tools. In this paper, we present a Docker-based environment for Flutter app developments across Windows, Linux, and Mac through Visual Studio Code, ensuring a unified learning experience. This paper aims to simplify complex configurations and address the obstacles encountered by students when initiating Flutter projects. For the evaluation, we prepared three simple Flutter projects along with the setup environment in a Docker container. Then, we asked 24 Master's students at Okayama University, Japan, to install the environment and modify the source codes in the projects independently by following the given instructions. The results show that all the students successfully completed the assignments, which confirms the efficiency and validity of our proposal. en-copyright= kn-copyright= en-aut-name=AungSoe Thandar en-aut-sei=Aung en-aut-mei=Soe Thandar kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AungLynn Htet en-aut-sei=Aung en-aut-mei=Lynn Htet kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KinariSafira Adine en-aut-sei=Kinari en-aut-mei=Safira Adine kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MentariMustika en-aut-sei=Mentari en-aut-mei=Mustika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=WaiKhaing Hsu en-aut-sei=Wai en-aut-mei=Khaing Hsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=2 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=3 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=4 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=5 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= affil-num=6 en-affil=Department of Information and Communication Systems, Okayama University kn-affil= en-keyword=Flutter kn-keyword=Flutter en-keyword=Dart kn-keyword=Dart en-keyword=app kn-keyword=app en-keyword=Docker kn-keyword=Docker en-keyword=Visual Studio Code kn-keyword=Visual Studio Code en-keyword=environment kn-keyword=environment en-keyword=code modification kn-keyword=code modification END start-ver=1.4 cd-journal=joma no-vol=141 cd-vols= no-issue= article-no= start-page=106955 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=202404 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Vibriosis in South Asia: A systematic review and meta-analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Objectives: South Asia remains home to foodborne diseases caused by the Vibrio species. We aimed to compile and update information on the epidemiology of vibriosis in South Asia.
Methods: For this systematic review and meta-analysis, we searched PubMed, Web of Science, EMBASE, and Google Scholar for studies related to vibriosis in South Asia published up to May 2023. A random-effects meta-analysis was used to estimate the pooled isolation rate of non-cholera-causing Vibrio species.
Results: In total, 38 studies were included. Seven of these were case reports and 22 were included in the meta-analysis. The reported vibriosis cases were caused by non-O1/non-O139 V. cholerae, V. parahaemolyticus, V. fluvialis, and V. vulnificus. The overall pooled isolation rate was 4.0% (95% confidence interval [CI] 3.0-5.0%) in patients with diarrhea. Heterogeneity was high (I-2 = 98.0%). The isolation rate of non-O1/non-O139 V. cholerae, V. parahaemolyticus, and V. fluvialis were 9.0 (95% CI 7.0-10.0%), 1.0 (95% CI 1.0-2.0%), and 2.0 (95% CI: 1.0-3.0%), respectively. Regarding V. parahaemolyticus, O3:K6 was the most frequently isolated serotype. Cases peaked during summer. Several studies reported antibiotic-resistant strains and those harboring extended-spectrum beta-lactamases genes.
Conclusions: This study demonstrates a high burden of infections caused by non-cholera-causing Vibrio species in South Asia. en-copyright= kn-copyright= en-aut-name=MuzemboBasilua Andre en-aut-sei=Muzembo en-aut-mei=Basilua Andre kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KitaharaKei en-aut-sei=Kitahara en-aut-mei=Kei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OhnoAyumu en-aut-sei=Ohno en-aut-mei=Ayumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KhatiwadaJanuka en-aut-sei=Khatiwada en-aut-mei=Januka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=DuttaShanta en-aut-sei=Dutta en-aut-mei=Shanta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MiyoshiShin-Ichi en-aut-sei=Miyoshi en-aut-mei=Shin-Ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Social Work Institute kn-affil= affil-num=5 en-affil=Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases kn-affil= affil-num=6 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Vibrio parahaemolyticus kn-keyword=Vibrio parahaemolyticus en-keyword=Vibrio vulnificus kn-keyword=Vibrio vulnificus en-keyword=Vibrio mimicus kn-keyword=Vibrio mimicus en-keyword=Vibrio fluvialis kn-keyword=Vibrio fluvialis en-keyword=Seafood kn-keyword=Seafood en-keyword=Gastroenteritis kn-keyword=Gastroenteritis END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue= article-no= start-page=191 end-page=205 dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240329 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Proposal for Creativity-oriented Inquiry-based Classes for Liberal Arts Education in Universities Analysis of Practical Results of the Liberal Arts Education Class “Creativity in Life” at Okayama University II kn-title=大学教養教育に適した創造性を重視した探究型授業の提案　岡山大学教養教育科目「生活の中の創造性」の実践結果の分析U en-subtitle= kn-subtitle= en-abstract=　In anticipation of the academic year 2025, when high school students who have experienced inquiry-based learning under the new Courses of Study will be university students, we have developed a new class that combines knowledge of physics and clothing science on the subject of "color" and incorporates project-based activities as a university liberal arts education course. As in the previous year, the class encourages students to take initiative and stimulates creative thinking by incorporating devices that encourage them to perceive things with an awareness of various connections and to become aware of the characteristics of their own thinking and senses. As a result of the analysis of the students' descriptions on the shuttle cards, the webbing created in the process of discussion, and the CLASS survey paper that measures students' thoughts and attitudes toward physics and physics learning, it became clear that the class was highly effective in encouraging students to "become aware of their own existence to think, feel, and judge independently and interactively. This is an essential element in the cultivation of creativity, which is important as a foundation for inquiry-based learning. kn-abstract=新学習指導要領で探究的な学びを経験した高校生が大学で学び始める2025年度を控え，大学の教養教育科目として，「色」を主題にして物理学と被服学の知見を組み合わせ，プロジェクト型の活動も組み入れた新たな授業を開発し実践した。昨年度の実践と同様に，様々なつながりを意識してものごとを捉えたり，学生自身の思考や感覚の特徴を自覚させることを促す仕掛けを組み込むことで，学生の主体性を促して創造的な思考を刺激する授業になっている。受講生のシャトルカードの記述，考察過程で作成したウェビング，物理や物理学習に対する学生の思考や態度を測定するCLASS調査紙などの分析の結果，「主体的，対話的に考え，感じ，判断する自分自身の存在を意識すること」を促す効果が大きいことが明らかになった。これは，探究的な学びの土台として重要な創造性の涵養に欠かせない要素になる。 en-copyright= kn-copyright= en-aut-name=INADAYoshihiko en-aut-sei=INADA en-aut-mei=Yoshihiko kn-aut-name=稲田佳彦 kn-aut-sei=稲田 kn-aut-mei=佳彦 aut-affil-num=1 ORCID= en-aut-name=SHINOHARAYoko en-aut-sei=SHINOHARA en-aut-mei=Yoko kn-aut-name=篠原陽子 kn-aut-sei=篠原 kn-aut-mei=陽子 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=探究型授業 kn-keyword=探究型授業 en-keyword=創造性 kn-keyword=創造性 en-keyword=物理学 kn-keyword=物理学 en-keyword=被服学 kn-keyword=被服学 en-keyword=ウェビング kn-keyword=ウェビング en-keyword=creativity kn-keyword=creativity en-keyword=physics kn-keyword=physics en-keyword=clothing science kn-keyword=clothing science END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=2 article-no= start-page=987 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240112 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Induced Pluripotent Stem Cell-Derived Cardiomyocytes Therapy for Ischemic Heart Disease in Animal Model: A Meta-Analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Ischemic heart disease (IHD) poses a significant challenge in cardiovascular health, with current treatments showing limited success. Induced pluripotent derived-cardiomyocyte (iPSC-CM) therapy within regenerative medicine offers potential for IHD patients, although its clinical impacts remain uncertain. This study utilizes meta-analysis to assess iPSC-CM outcomes in terms of efficacy and safety in IHD animal model studies. A meta-analysis encompassing PUBMED, ScienceDirect, Web of Science, and the Cochrane Library databases, from inception until October 2023, investigated iPSC therapy effects on cardiac function and safety outcomes. Among 51 eligible studies involving 1012 animals, despite substantial heterogeneity, the iPSC-CM transplantation improved left ventricular ejection fraction (LVEF) by 8.23% (95% CI, 7.15 to 9.32%; p < 0.001) compared to control groups. Additionally, cell-based treatment reduced the left ventricle fibrosis area and showed a tendency to reduce left ventricular end-systolic volume (LVESV) and end-diastolic volume (LVEDV). No significant differences emerged in mortality and arrhythmia risk between iPSC-CM treatment and control groups. In conclusion, this meta-analysis indicates iPSC-CM therapy's promise as a safe and beneficial intervention for enhancing heart function in IHD. However, due to observed heterogeneity, the efficacy of this treatment must be further explored through large randomized controlled trials based on rigorous research design. en-copyright= kn-copyright= en-aut-name=VoQuan Duy en-aut-sei=Vo en-aut-mei=Quan Duy kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SaitoYukihiro en-aut-sei=Saito en-aut-mei=Yukihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NakamuraKazufumi en-aut-sei=Nakamura en-aut-mei=Kazufumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=IidaToshihiro en-aut-sei=Iida en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YuasaShinsuke en-aut-sei=Yuasa en-aut-mei=Shinsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of Cardiovascular Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Department of Cardiovascular Medicine, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of Cardiovascular Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Department of Cardiovascular Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Department of Cardiovascular Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=induced pluripotent stem cell kn-keyword=induced pluripotent stem cell en-keyword=ischemic heart disease kn-keyword=ischemic heart disease en-keyword=outcomes kn-keyword=outcomes en-keyword=safety kn-keyword=safety en-keyword=meta-analysis kn-keyword=meta-analysis END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue=1 article-no= start-page=e914 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20231226 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Clinical parameter-guided initial resuscitation in adult patients with septic shock: A systematic review and network meta-analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Aim: To identify the most useful tissue perfusion parameter for initial resuscitation in sepsis/septic shock adults using a network meta-analysis.
Methods: We searched major databases until December 2022 for randomized trials comparing four tissue perfusion parameters or against usual care. The primary outcome was short-term mortality up to 90?days. The Confidence in Network Meta-Analysis web application was used to assess the quality of evidence.
Results: Seventeen trials were identified. Lactate-guided therapy (risk ratios, 0.59; 95% confidence intervals [0.45?0.76]; high certainty) and capillary refill time-guided therapy (risk ratios, 0.53; 95% confidence intervals [0.33?0.86]; high certainty) were significantly associated with lower short-term mortality compared with usual care, whereas central venous oxygen saturation-guided therapy (risk ratio, 1.50; 95% confidence intervals [1.16?1.94]; moderate certainty) increased the risk of short-term mortality compared with lactate-guided therapy.
Conclusions: Lactate or capillary refill time-guided initial resuscitation for sepsis/septic shock patients may decrease short-term mortality. More research is essential to personalize and optimize treatment strategies for septic shock resuscitation. en-copyright= kn-copyright= en-aut-name=YumotoTetsuya en-aut-sei=Yumoto en-aut-mei=Tetsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KuribaraTomoki en-aut-sei=Kuribara en-aut-mei=Tomoki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YamadaKohei en-aut-sei=Yamada en-aut-mei=Kohei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SatoTakehito en-aut-sei=Sato en-aut-mei=Takehito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KobaShigeru en-aut-sei=Koba en-aut-mei=Shigeru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TetsuharaKenichi en-aut-sei=Tetsuhara en-aut-mei=Kenichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KashiuraMasahiro en-aut-sei=Kashiura en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=SakurayaMasaaki en-aut-sei=Sakuraya en-aut-mei=Masaaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=School of Nursing, Sapporo City University kn-affil= affil-num=3 en-affil=Department of Traumatology and Critical Care Medicine, National Defense Medical College Hospital kn-affil= affil-num=4 en-affil=Department of Anesthesiology, Nagoya University Hospital kn-affil= affil-num=5 en-affil=Department of Critical Care Medicine, Nerima Hikarigaoka Hospital kn-affil= affil-num=6 en-affil=Department of Critical Care Medicine, Fukuoka Children's Hospital kn-affil= affil-num=7 en-affil=Department of Emergency and Critical Care Medicine, Saitama Medical Center, Jichi Medical University kn-affil= affil-num=8 en-affil=Department of Emergency and Intensive Care Medicine, JA Hiroshima General Hospital kn-affil= en-keyword=capillary refill timecarbon dioxide gapcentral venous oxygen saturationlactatenetwork meta-analysissepsisseptic shock kn-keyword=capillary refill timecarbon dioxide gapcentral venous oxygen saturationlactatenetwork meta-analysissepsisseptic shock END start-ver=1.4 cd-journal=joma no-vol=183 cd-vols= no-issue= article-no= start-page=1 end-page=14 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230920 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Measurement of the Team Processes Based on Phases of Activities: Investigation on College Team Sports kn-title=活動フェイズを考慮したチームプロセスの測定 ― 大学チームスポーツを対象にして ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究では，チームワークの行動的側面であるチームプロセスに着目し，Marks et al. （2001）の理論的枠組みに基づいて，時間経過に応じて遷移するチームの活動フェイズを考慮した測定尺度の試案を作成した。尺度は３つの活動フェイズごとに，移行プロセス，実行プロセス，対人関係調整プロセスの項目を構成した。チームスポーツ競技者である大学生を対象にWeb調査を行い，224 名から有効回答が得られた。探索的因子分析によって各プロセスの行動要素として解釈可能な因子を抽出し，内的整合性の観点から高い信頼性を確認できた。また確認的因子分析により，包括的なチームプロセスを高次因子とするモデルを検証した。さらに，チームリフレクションおよびチームへのコミットメントとの関連から，尺度の妥当性を検討した。得られた結果を基に，尺度の精緻化と今後の実証的検討課題を考察した。 en-copyright= kn-copyright= en-aut-name=MISAWARyo en-aut-sei=MISAWA en-aut-mei=Ryo kn-aut-name=三沢良 kn-aut-sei=三沢 kn-aut-mei=良 aut-affil-num=1 ORCID= en-aut-name=HASEGAWANaoko en-aut-sei=HASEGAWA en-aut-mei=Naoko kn-aut-name=長谷川尚子 kn-aut-sei=長谷川 kn-aut-mei=尚子 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Faculty of Human Sciences, Department of Psychology, Bunkyo University kn-affil=文教大学人間科学部心理学科 en-keyword=チームワーク kn-keyword=チームワーク en-keyword=チームプロセス kn-keyword=チームプロセス en-keyword=活動フェイズ kn-keyword=活動フェイズ en-keyword=チームスポーツ kn-keyword=チームスポーツ END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=e1579 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220312 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Echelon analysis and its software for spatial lattice data en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this study, we explore the use of echelon analysis and its software named EcheScan for spatial lattice data. EcheScan is developed as a web application via an internet browser in R language and Shiny server for echelon analysis. The technique of echelon is proposed to analyze the topological structure for spatial lattice data. The echelon tree provides a dendrogram representation. Regional features, such as hierarchical spatial data structure and hotspots clusters, are shown in an echelon dendrogram. In addition, we introduce the conception of echelon with the values and neighbors for lattice data. We also explain the use of EcheScan for one- and two-dimensional regular lattice data. Furthermore, coronavirus disease 2019 death data corresponding to 50 US states are illustrated using EcheScan as an example of geospatial lattice data.

This article is categorized under:
　Statistical Learning and Exploratory Methods of the Data Sciences > Exploratory Data Analysis
　Statistical Learning and Exploratory Methods of the Data Sciences > Clustering and Classification
　Data: Types and Structure > Image and Spatial Data en-copyright= kn-copyright= en-aut-name=KuriharaKoji en-aut-sei=Kurihara en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IshiokaFumio en-aut-sei=Ishioka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil= en-keyword=echelon analysis kn-keyword=echelon analysis en-keyword=hierarchical structure kn-keyword=hierarchical structure en-keyword=R language and shiny kn-keyword=R language and shiny en-keyword=spatial lattice data kn-keyword=spatial lattice data en-keyword=web application kn-keyword=web application END start-ver=1.4 cd-journal=joma no-vol=14 cd-vols= no-issue=6 article-no= start-page=300 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230523 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A Web-Based Docker Image Assistant Generation Tool for User-PC Computing System en-subtitle= kn-subtitle= en-abstract= kn-abstract=Currently, we are developing the user-PC computing (UPC) system based on the master-worker model as a scalable, low-cost, and high-performance computing platform. To run various application programs on personal computers (PCs) with different environments for workers, it adopts Docker technology to bundle every necessary software as one image file. Unfortunately, the Docker file/image are manually generated through multiple steps by a user, which can be the bottleneck. In this paper, we present a web-based Docker image assistant generation (DIAG) tool in the UPC system to assist or reduce these process steps. It adopts Angular JavaScript for offering user interfaces, PHP Laravel for handling logic using RestAPI, MySQL database for storing data, and Shell scripting for speedily running the whole program. In addition, the worker-side code modification function is implemented so that a user can modify the source code of the running job and update the Docker image at a worker to speed up them. For evaluations, we collected 30 Docker files and 10 OpenFOAM jobs through reverse processing from Docker images in Github and generated the Docker images using the tool. Moreover, we modified source codes for network simulations and generated the Docker images in a worker five times. The results confirmed the validity of the proposal. en-copyright= kn-copyright= en-aut-name=AungLynn Htet en-aut-sei=Aung en-aut-mei=Lynn Htet kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AungSoe Thandar en-aut-sei=Aung en-aut-mei=Soe Thandar kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ZhouXudong en-aut-sei=Zhou en-aut-mei=Xudong kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=XiangXu en-aut-sei=Xiang en-aut-mei=Xu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KaoWen-Chung en-aut-sei=Kao en-aut-mei=Wen-Chung kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=6 en-affil=Department of Electrical Engineering, National Taiwan Normal University kn-affil= en-keyword=Docker kn-keyword=Docker en-keyword=automatic generation kn-keyword=automatic generation en-keyword=Angular kn-keyword=Angular en-keyword=Laravel kn-keyword=Laravel en-keyword=MySQL kn-keyword=MySQL en-keyword=Shell scripting kn-keyword=Shell scripting en-keyword=image update kn-keyword=image update en-keyword=UPC system kn-keyword=UPC system END start-ver=1.4 cd-journal=joma no-vol=52 cd-vols= no-issue= article-no= start-page=102554 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=202304 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Shigellosis in Southeast Asia: A systematic review and meta-analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: Southeast Asia is attractive for tourism. Unfortunately, travelers to this region are at risk of becoming infected with Shigella. We conducted a meta-analysis to provide updates on Shigella prevalence in Southeast Asia, along with their serogroups and serotypes.
Methods: We conducted a systematic search using PubMed, EMBASE, and Web of Science for peer-reviewed studies from 2000 to November 2022. We selected studies that detected Shigella in stools by culture or polymerase chain reaction (PCR). Two reviewers extracted the data using a standardized form and performed quality assessments using the Joanna Briggs Institute checklist. The random effects model was used to estimate the pooled prevalence of Shigella.
Results: During our search, we identified 4376 studies. 29 studies (from six Southeast Asian countries) were included in the systematic review, 21 each in the meta-analysis of the prevalence of Shigella (Sample size: 109545) and the prevalence of Shigella serogroups.
The pooled prevalence of Shigella was 4% (95% CI: 4?5%) among diarrhea cases. Shigella sonnei was the most abundant serogroup in Thailand (74%) and Vietnam (57%), whereas Shigella flexneri was dominant in Indonesia (72%) and Cambodia (71%). Shigella dysenteriae and Shigella boydii were uncommon (pooled prevalence of 1% each). The pooled prevalence of Shigella was 5% (95% CI: 4?6%) in children aged <5 years. The pooled prevalence showed a decreasing trend comparing data collected between 2000?2013 (5%; 95% CI: 4?6%) and between 2014?2022 (3%; 95% CI: 2?4%). Shigella prevalence was 6% in studies that included participants with mixed pathogens versus 3% in those without. Shigella flexneri serotype 2a was the most frequently isolated (33%), followed by 3a (21%), 1b (10%), 2b (3%), and 6 (3%).
Conclusions: This study provides compelling evidence for the development of effective Shigella vaccines for residents of endemic regions and travellers to these areas. en-copyright= kn-copyright= en-aut-name=MuzemboBasilua Andre en-aut-sei=Muzembo en-aut-mei=Basilua Andre kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KitaharaKei en-aut-sei=Kitahara en-aut-mei=Kei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MitraDebmalya en-aut-sei=Mitra en-aut-mei=Debmalya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OhnoAyumu en-aut-sei=Ohno en-aut-mei=Ayumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KhatiwadaJanuka en-aut-sei=Khatiwada en-aut-mei=Januka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=DuttaShanta en-aut-sei=Dutta en-aut-mei=Shanta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=MiyoshiShin-Ichi en-aut-sei=Miyoshi en-aut-mei=Shin-Ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Collaborative Research Centre of Okayama University for Infectious Diseases in India at ICMR-NICED kn-affil= affil-num=4 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Social Work Institute kn-affil= affil-num=6 en-affil=Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases kn-affil= affil-num=7 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=Shigella vaccine kn-keyword=Shigella vaccine en-keyword=Shigella sonnei kn-keyword=Shigella sonnei en-keyword=Shigella flexneri kn-keyword=Shigella flexneri en-keyword=Diarrhea kn-keyword=Diarrhea en-keyword=Dysentery kn-keyword=Dysentery en-keyword=Shiga toxin kn-keyword=Shiga toxin en-keyword=Travel kn-keyword=Travel END start-ver=1.4 cd-journal=joma no-vol=77 cd-vols= no-issue=3 article-no= start-page=311 end-page=318 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=202306 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Current Femoral Stem Fixation Selection in Hip-Fracture Bipolar Hemiarthroplasties, and Factors Affecting Surgeons’ Confidence in Their Ability to Teach about Cemented Stems: A Questionnaire in a Region of Japan with Super-Aged Patients en-subtitle= kn-subtitle= en-abstract= kn-abstract=Japan’s hip fracture management guidelines now recommend the use of cemented stems in cases of bone fragility. However, the current stem selection practices in bipolar hemiarthroplasty (BHA) in a super-aging area in Japan remain unclear. This study aimed to examine the stem selection policies, the surgeons’ concerns about cemented stems, and factors affecting their confidence in their ability to coach others on cemented stem procedures. Ninety-four orthopedic surgeons (27 facilities) responded to our web-based questionnaire conducted in January/February 2022. Cementless stem was the first choice of 97.8% of the surgeons; <15% of the respondents expected to increase their use of cemented stems in the future. The cement technique was the greatest concern; almost half of the surgeons described having insufficient experience with cemented stems. The factor that most affected the surgeons’ expertise in using cemented stems is the number of surgeries they had conducted with a cemented stem (multivariable analysis odds ratio 8.42, p=0.001). Greater experience was associated with increased expertise of the surgeons in using cemented stems, with a threshold of 11 cases showing sensitivity of 41.7% and specificity of 98.3% for their confidence to instruct cemented stems. en-copyright= kn-copyright= en-aut-name=MiuraTakanori en-aut-sei=Miura en-aut-mei=Takanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KijimaHiroaki en-aut-sei=Kijima en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TazawaHiroshi en-aut-sei=Tazawa en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MiyakoshiNaohisa en-aut-sei=Miyakoshi en-aut-mei=Naohisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Orthopedic Surgery, Tazawako Hospital kn-affil= affil-num=2 en-affil=Akita Hip Research Group, Akita University Graduate School of Medicine kn-affil= affil-num=3 en-affil=Akita Hip Research Group, Akita University Graduate School of Medicine kn-affil= affil-num=4 en-affil=Akita Hip Research Group, Akita University Graduate School of Medicine kn-affil= en-keyword=hip fracture kn-keyword=hip fracture en-keyword=arthroplasty kn-keyword=arthroplasty en-keyword=bone cement kn-keyword=bone cement en-keyword=questionnaire kn-keyword=questionnaire END start-ver=1.4 cd-journal=joma no-vol=13 cd-vols= no-issue= article-no= start-page=261 end-page=273 dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Development of Cross-curricular Classes that Contribute to the Cultivation of Creativity Analysis of Practical Results of the Liberal Arts Education Class “Creativity in Life” at Okayama University kn-title=創造性の涵養に資する教科横断型授業の開発 岡山大学教養教育「生活の中の創造性」の実践結果の分析 en-subtitle= kn-subtitle= en-abstract=In recent years, education to cultivate creativity has been developing in Japan and abroad, and classes that stimulate creativity across subject areas, such as Period for Inquiry-Based Cross-Disciplinary Study and STEAM education, are being developed. We have developed and implemented a new class on the topic of ‘color’ as a liberal arts education course at a university, combining knowledge of physics and clothing science and incorporating project-based activities. By incorporating mechanisms that encourage students to perceive things with an awareness of various connections and to become aware of the characteristics of their own thinking and senses, the class stimulates students for proactive and creativity. Analysis of the shuttle card, webbing in the discussion process, and the CLASS which measures students' thinking and attitudes toward physics and physical learning, revealed that the program was highly effective in promoting ‘awareness of one's own existence to think, feel, and judge’ which is essential to cultivate creativity. kn-abstract=近年，創造性の涵養を重視する教育が国内外で盛んになり，総合的な探究の時間やSTEAM 教育など，教科横断的に創造性を刺激する授業の開発も進んでいる。我々は，大学の教養教 育科目として，「色」を主題にして物理学と被服学の知見を組み合わせ，プロジェクト型の 活動も組み入れた新たな授業を開発し実践した。様々なつながりを意識してものごとを捉 えたり，学生自身の思考や感覚の特徴を自覚させることを促す仕掛けを組み込むことで， 学生の主体性を促して創造的な思考を刺激する授業になっている。受講生のシャトルカー ドの記述，考察過程で作成したウェビング，物理や物理学習に対する学生の思考や態度を 測定するCLASS 調査紙などの分析の結果，創造性の涵養に欠かせない，「考え，感じ，判断 する自分自身の存在を意識すること」を促す効果が大きいことが明らかになった。 en-copyright= kn-copyright= en-aut-name=InadaYoshihiko en-aut-sei=Inada en-aut-mei=Yoshihiko kn-aut-name=稲田佳彦 kn-aut-sei=稲田 kn-aut-mei=佳彦 aut-affil-num=1 ORCID= en-aut-name=ShinoharaYoko en-aut-sei=Shinohara en-aut-mei=Yoko kn-aut-name=篠原陽子 kn-aut-sei=篠原 kn-aut-mei=陽子 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=創造性 (creativity) kn-keyword=創造性 (creativity) en-keyword=物理学 (physics) kn-keyword=物理学 (physics) en-keyword=被服学 (clothing science) kn-keyword=被服学 (clothing science) en-keyword=STEAM 教育 (STEAM education) kn-keyword=STEAM 教育 (STEAM education) en-keyword=ICT kn-keyword=ICT END start-ver=1.4 cd-journal=joma no-vol=181 cd-vols= no-issue= article-no= start-page=1 end-page=14 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20221125 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Task Characteristics that Determine the Virtual Interactions of Teams: Implications for Effective Use of Digital Tools kn-title=チームのバーチャルな相互作用を規定する課題特性 ―デジタルツールの効果的活用への示唆― en-subtitle= kn-subtitle= en-abstract= kn-abstract=近年，わが国の企業ではデジタルトランスフォーメーション（DX）の推進を背景に，多様なデジタルツールが職場に導入されている。本研究では，職務遂行チームでデジタルツールを使用して交わされるバーチャルな相互作用に対し，課題特性が及ぼす影響を探索的に検討した。既往知見に基づき，バーチャル性認知（バーチャルな相互作用の指標）や課題特性などに関する質問項目を作成した。Web調査で収集した大都市部の企業に勤務する正社員360 名の回答を分析した結果，課題特性の影響は企業規模に応じて異なる傾向を示した。中小規模の企業では，「相互依存性」や「自律性」の課題特性が相互作用の活性化へ直接的に作用していた。一方，大規模の企業では，「多様性」や「自律性」の課題特性は、デジタルツールの使用が相互作用の活性化をもたらすための限定条件として機能することが示唆された。 en-copyright= kn-copyright= en-aut-name=MisawaRyo en-aut-sei=Misawa en-aut-mei=Ryo kn-aut-name=三沢良 kn-aut-sei=三沢 kn-aut-mei=良 aut-affil-num=1 ORCID= en-aut-name=FujimuraMakoto en-aut-sei=Fujimura en-aut-mei=Makoto kn-aut-name=藤村まこと kn-aut-sei=藤村 kn-aut-mei=まこと aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Faculty of Human Relations, Fukuoka Jo Gakuin University kn-affil=福岡女学院大学人間関係学部 en-keyword=バーチャル性 kn-keyword=バーチャル性 en-keyword=チームワーク kn-keyword=チームワーク en-keyword=課題特性 kn-keyword=課題特性 en-keyword=デジタルツール kn-keyword=デジタルツール END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=1 article-no= start-page=22 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20221001 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Colonization with extended-spectrum beta-lactamase-producing Escherichia coli and traveler's diarrhea attack rates among travelers to India: a systematic review and meta-analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background India is an attractive destination for travelers. Unfortunately, numerous reports exist on traveler's diarrhea (TD) and fecal colonization with extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-EC) among international travelers visiting India. Here, we systematically reviewed studies published on the acquisition of ESBL-EC and TD attack rates among international visitors to India. Methods Design: Systematic review and meta-analysis. A systematic search was performed using Google Scholar, PubMed, EMBASE, Web of Science, and gray literature from 2000 to December 2021, for studies containing data for ESBL-EC acquisition or TD experience related to a trip to India. Random effects models were used to compute the prevalence of ESBL-EC acquisition and TD attack. Results The literature search yielded a total of 5023 records. Of these, 31 met our inclusion criteria for systematic review and only 17 could be meta-analyzed (9 for TD, and 8 for ESBL-EC). The overall pooled attack rate of TD was 39% (95% confidence interval, CI: 25-53%). In studies where travelers' memory was used to diagnose TD, the pooled attack rate of TD was slightly higher (42%, 95% CI: 21-64%) compared to those where TD was objectively documented (33%, 95% CI: 17-49%). There were significant risks to be colonized with ESBL-EC among the travelers who experienced TD. The pooled rate of ESBL-EC colonization was 72% (CI: 67-78%). Most ESBL-EC produced CTX-M-15 enzyme. Furthermore, most of the travelers who acquired ESBL-EC were from highly industrialized countries recruited from travel clinics: Canada (n = 80), Germany (n = 69), Netherlands (n = 20), Sweden (n = 18), Japan (n = 10), Finland (n = 8), USA (n = 7), Spain (n = 5), and Denmark (n = 3). Conclusions TD pooled attack rate and ESBL-EC acquisition among international travelers visiting India were high in this study. However, we cannot make generalizations based upon this TD pooled attack rate for the current situation, due to a lack of current data. Our study highlights that travelers should be advised on TD to ensure that they do not disregard the risk of contracting TD and be better prepared as a result. It also illustrates the importance of international travel in acquiring antibiotic-resistant Escherichia coli. en-copyright= kn-copyright= en-aut-name=MuzemboBasilua Andre en-aut-sei=Muzembo en-aut-mei=Basilua Andre kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KitaharaKei en-aut-sei=Kitahara en-aut-mei=Kei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OhnoAyumu en-aut-sei=Ohno en-aut-mei=Ayumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OkamotoKeinosuke en-aut-sei=Okamoto en-aut-mei=Keinosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MiyoshiShin-Ichi en-aut-sei=Miyoshi en-aut-mei=Shin-Ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=ESBL-EC kn-keyword=ESBL-EC en-keyword=Traveler's diarrhea kn-keyword=Traveler's diarrhea en-keyword=International travelers kn-keyword=International travelers en-keyword=India kn-keyword=India en-keyword=Meta-analysis kn-keyword=Meta-analysis END start-ver=1.4 cd-journal=joma no-vol=180 cd-vols= no-issue= article-no= start-page=17 end-page=26 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220826 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Psychological Safety in the Teachers’ Room: Investigation of Interpersonal Risks that Hinder Teachers’ Collaboration kn-title=職員室の心理的安全性 ―教師の協働を阻む対人関係リスクに関する検討― en-subtitle= kn-subtitle= en-abstract= kn-abstract=本研究では，学校の教師を対象に心理的安全性とそれを阻害する対人関係リスク（率直な発言や意見表明に伴う不安）の実態を把握し，両者の関連について実証的に検討した。Web調査会社の登録モニタから公立学校の常勤教諭を抽出し，インターネットを通じた調査により783 名から有効回答が得られた（小学校338 名，中学校244 名，高等学校201 名）。相関分析により，心理的安全性と対人関係リスクの間には，予測通りの負の関連が確認された。詳細を吟味するために重回帰分析を行ったところ，「無知」「ネガティブ」「邪魔をする人」だと思われる不安が，心理的安全性を阻害することが示唆された。さらに学校種別の分析から，小学校では「邪魔をする人」だと思われる不安，中学校・高等学校では「ネガティブ」だと思われる不安が，心理的安全性を阻害する主要な対人関係リスクであることが示唆された。 en-copyright= kn-copyright= en-aut-name=MisawaRyo en-aut-sei=Misawa en-aut-mei=Ryo kn-aut-name=三沢良 kn-aut-sei=三沢 kn-aut-mei=良 aut-affil-num=1 ORCID= en-aut-name=KamadaMasafumi en-aut-sei=Kamada en-aut-mei=Masafumi kn-aut-name=鎌田雅史 kn-aut-sei=鎌田 kn-aut-mei=雅史 aut-affil-num=2 ORCID= affil-num=1 en-affil=Faculty of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Department of Infant Education, Shujitsu Junior College kn-affil=就実短期大学幼児教育学科 en-keyword=心理的安全性 kn-keyword=心理的安全性 en-keyword=教師 kn-keyword=教師 en-keyword=協働 kn-keyword=協働 en-keyword=対人関係リスク kn-keyword=対人関係リスク END start-ver=1.4 cd-journal=joma no-vol=76 cd-vols= no-issue=4 article-no= start-page=457 end-page=463 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=202208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Efficacy of 0.01% Atropine Eye Drops in Controlling Myopia Progression and Axial Elongation in Children: A Meta-analysis Based on Randomized Controlled Trials en-subtitle= kn-subtitle= en-abstract= kn-abstract=To clarify the preventive effects of 0.01% atropine eye drops against myopia progression and axial elongation in children, a meta-analysis was carried out based on data obtained from PubMed and Web of Science as of August 1, 2021. Randomized controlled trials (RCTs) that enrolled myopic children who had received atropine for at least one year were included in this study, Key search terms included myopia, children, and 0.01% or low-dose atropine. Heterogeneity was quantified by I2 statistics, and meta-analyses were performed using the fixed-effect model. Five RCTs involving 809 unique children were analyzed. One trial was excluded because of a poor Jadad score and markedly rapid myopia progression in controls. The mean effect sizes for 12 months in myopia progression and axial elongation synthesized from the remaining 4 RCTs were 0.20 (95% CI: 0.13 to 0.27) D and ?0.08 (?0.11 to ?0.04) mm, respectively (p<0.0001). The corresponding inhibition ratios were 28% and 19%. I2 statistics were 6% or less. Sensitivity analysis and funnel plots demonstrated the robustness of the estimation. The 0.01% atropine-induced inhibition ratio for myopia progression in Asian children was roughly half of that originally reported and did not reach the minimum requirement for clinical treatment. en-copyright= kn-copyright= en-aut-name=SunWeiying en-aut-sei=Sun en-aut-mei=Weiying kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HasebeSatoshi en-aut-sei=Hasebe en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Department of Ophthalmology 2, Kawasaki Medical School kn-affil= affil-num=2 en-affil=Department of Ophthalmology 2, Kawasaki Medical School kn-affil= en-keyword=myopia kn-keyword=myopia en-keyword=0.01% atropine kn-keyword=0.01% atropine en-keyword=low-dose atropine kn-keyword=low-dose atropine en-keyword=axial length kn-keyword=axial length en-keyword=myopia progression kn-keyword=myopia progression END start-ver=1.4 cd-journal=joma no-vol=76 cd-vols= no-issue=4 article-no= start-page=359 end-page=371 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=202208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Therapeutic Approaches Targeting miRNA in Systemic Lupus Erythematosus en-subtitle= kn-subtitle= en-abstract= kn-abstract=Systemic lupus erythematosus (SLE) is a potentially fatal systemic autoimmune disease, and its etiology involves both genetic and environmental factors such as sex hormone imbalance, genetic predisposition, epigenetic regulation, and immunological factors. Dysregulation of microRNA (miRNA) is suggested to be one of the epigenetic factors in SLE. miRNA is a 22-nucleotide single-stranded noncoding RNA that contributes to post-transcriptional modulation of gene expression. miRNA targeting therapy has been suggested to be useful for the treatment of cancers and other diseases. Gene knockout and miRNA targeting therapy have been demonstrated to improve SLE disease activity in mice. However, these approaches have not yet reached the level of clinical application. miRNA targeting therapy is limited by the fact that each miRNA has multiple targets. In addition, the expression of certain miRNAs may differ among cell tissues within a single SLE patient. This limitation can be overcome by targeted delivery and chemical modifications. In the future, further research into miRNA chemical modifications and delivery systems will help us develop novel therapeutic agents for SLE. en-copyright= kn-copyright= en-aut-name=Hiramatsu-AsanoSumie en-aut-sei=Hiramatsu-Asano en-aut-mei=Sumie kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=WadaJun en-aut-sei=Wada en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=systemic lupus erythematosus kn-keyword=systemic lupus erythematosus en-keyword=miRNA kn-keyword=miRNA en-keyword=miRNA targeting therapy kn-keyword=miRNA targeting therapy END start-ver=1.4 cd-journal=joma no-vol=86 cd-vols= no-issue=8 article-no= start-page=1312 end-page=1318 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=2022725 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Overview of the 86th Annual Scientific Meeting of the Japanese Circulation Society　― Cardiology Spreading Its Wings ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=The 86th Annual Scientific Meeting of the Japanese Circulation Society was held in a web-based format on March 11-13, 2022. In accordance with the internationalization policy of the JCS, the meeting was held with the Asian Pacific Society of Cardiology Congress 2022. The main theme was "Cardiology Spreading its Wings". The number of patients with heart failure and other cardiovascular diseases is increasing dramatically, and the fields dealt with by cardiovascular medicine are also greatly expanding. This conference was both intellectually satisfying and exciting for all participants, who numbered over 14,900. The meeting was completed with great success, and the enormous amount of cooperation and support from all involved was greatly appreciated. en-copyright= kn-copyright= en-aut-name=NakamuraKazufumi en-aut-sei=Nakamura en-aut-mei=Kazufumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MiyoshiToru en-aut-sei=Miyoshi en-aut-mei=Toru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AkagiSatoshi en-aut-sei=Akagi en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TohNorihisa en-aut-sei=Toh en-aut-mei=Norihisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SaitoYukihiro en-aut-sei=Saito en-aut-mei=Yukihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TakayaYoichi en-aut-sei=Takaya en-aut-mei=Yoichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YoshidaMasatoki en-aut-sei=Yoshida en-aut-mei=Masatoki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NakagawaKoji en-aut-sei=Nakagawa en-aut-mei=Koji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KawadaSatoshi en-aut-sei=Kawada en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=TodaHironobu en-aut-sei=Toda en-aut-mei=Hironobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=MikiTakashi en-aut-sei=Miki en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=NakayamaRie en-aut-sei=Nakayama en-aut-mei=Rie kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=YokohamaFumi en-aut-sei=Yokohama en-aut-mei=Fumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=IchikawaKeishi en-aut-sei=Ichikawa en-aut-mei=Keishi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=YoshidaMasashi en-aut-sei=Yoshida en-aut-mei=Masashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=TaniyamaMakiko en-aut-sei=Taniyama en-aut-mei=Makiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= en-aut-name=NishiiNobuhiro en-aut-sei=Nishii en-aut-mei=Nobuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=17 ORCID= en-aut-name=AkagiTeiji en-aut-sei=Akagi en-aut-mei=Teiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=18 ORCID= en-aut-name=MoritaHiroshi en-aut-sei=Morita en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=19 ORCID= en-aut-name=ItoHiroshi en-aut-sei=Ito en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=20 ORCID= affil-num=1 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=10 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=11 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=12 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=13 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=14 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=15 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=16 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=17 en-affil=Department of Cardiovascular Therapeutics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=18 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=19 en-affil=Department of Cardiovascular Therapeutics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=20 en-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=Cardiology kn-keyword=Cardiology en-keyword=Heart failure kn-keyword=Heart failure en-keyword=Internationalization kn-keyword=Internationalization END start-ver=1.4 cd-journal=joma no-vol=11 cd-vols= no-issue=11 article-no= start-page=2095 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20211113 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Cholera Rapid Diagnostic Tests for the Detection of Vibrio cholerae O1: An Updated Meta-Analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=The rapid diagnosis of cholera contributes to adequate outbreak management. This meta-analysis assesses the diagnostic accuracy of cholera rapid tests (RDTs) to detect Vibrio cholerae O1. Methods: Systematic review and meta-analysis. We searched four databases (Medline, EMBASE, Google Scholar, and Web of Science up to 8 September 2021) for studies that evaluated cholera RDTs for the detection of V. cholerae O1 compared with either stool culture or polymerase chain reaction (PCR). We assessed the studies' quality using the QUADAS-2 criteria. In addition, in this update, GRADE approach was used to rate the overall certainty of the evidence. We performed a bivariate random-effects meta-analysis to calculate the pooled sensitivity and specificity of cholera RDTs. Results: Overall, 20 studies were included in this meta-analysis. Studies were from Africa (n = 11), Asia (n = 7), and America (Haiti; n = 2). They evaluated eight RDTs (Crystal VC-O1, Crystal VC, Cholkit, Institut Pasteur cholera dipstick, SD Bioline, Artron, Cholera Smart O1, and Smart II Cholera O1). Using direct specimen testing, sensitivity and specificity of RDTs were 90% (95% CI, 86 to 93) and 86% (95% CI, 81 to 90), respectively. Cholera Sensitivity was higher in studies conducted in Africa [92% (95% CI, 89 to 94)] compared with Asia [82% (95% CI, 77 to 87)]. However, specificity [83% (95% CI, 71 to 91)] was lower in Africa compared with Asia [90% (95% CI, 84 to 94)]. GRADE quality of evidence was estimated as moderate. Conclusions: Against culture or PCR, current cholera RDTs have moderate sensitivity and specificity for detecting Vibrio cholerae O1. en-copyright= kn-copyright= en-aut-name=MuzemboBasilua Andre en-aut-sei=Muzembo en-aut-mei=Basilua Andre kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KitaharaKei en-aut-sei=Kitahara en-aut-mei=Kei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OhnoAyumu en-aut-sei=Ohno en-aut-mei=Ayumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=DebnathAnusuya en-aut-sei=Debnath en-aut-mei=Anusuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OkamotoKeinosuke en-aut-sei=Okamoto en-aut-mei=Keinosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MiyoshiShin-Ichi en-aut-sei=Miyoshi en-aut-mei=Shin-Ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=6 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=rapid test kn-keyword=rapid test en-keyword=cholera kn-keyword=cholera en-keyword=Vibrio cholera O1 kn-keyword=Vibrio cholera O1 en-keyword=sensitivity kn-keyword=sensitivity en-keyword=specificity kn-keyword=specificity en-keyword=accuracy kn-keyword=accuracy en-keyword=update kn-keyword=update END start-ver=1.4 cd-journal=joma no-vol=19 cd-vols= no-issue=12 article-no= start-page=7141 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220610 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Long-Term Kinetics of Serological Antibodies against Vibrio cholerae Following a Clinical Cholera Case: A Systematic Review and Meta-Analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: Approximately 2.9 million people worldwide suffer from cholera each year, many of whom are destitute. However, understanding of immunity against cholera is still limited. Several studies have reported the duration of antibodies following cholera; however, systematic reviews including a quantitative synthesis are lacking. Objective: To meta-analyze cohort studies that have evaluated vibriocidal, cholera toxin B subunit (CTB), and lipopolysaccharide (LPS) antibody levels following a clinical cholera case. Methods: Design: Systematic review and meta-analysis. We searched PubMed and Web of science for studies assessing antibodies against Vibrio cholerae in cohorts of patients with clinical cholera. Two authors independently extracted data and assessed the quality of included studies. Random effects models were used to pool antibody titers in adults and older children (aged >= 6 years). In sensitivity analysis, studies reporting data on young children (2-5 years) were included. Results: Nine studies met our inclusion criteria for systematic review and seven for meta-analysis. The pooled mean of vibriocidal antibody titers in adults and older children (aged >= 6 years) was 123 on day 2 post-symptom onset, which sharply increased on day 7 (pooled mean = 6956) and gradually waned to 2247 on day 30, 578 on day 90, and 177 on day 360. Anti-CTB IgA antibodies also peaked on day 7 (pooled mean = 49), followed by a rapid decrease on day 30 (pooled mean = 21), and further declined on day 90 (pooled mean = 10), after which it plateaued from day 180 (pooled mean = 8) to 360 (pooled mean = 6). Similarly, anti-CTB IgG antibodies peaked in early convalescence between days 7 (pooled mean = 65) and 30 (pooled mean = 69), then gradually waned on days 90 (pooled mean = 42) and 180 (pooled mean = 30) and returned to baseline on day 360 (pooled mean = 24). Anti-LPS IgA antibodies peaked on day 7 (pooled mean = 124), gradually declined on day 30 (pooled mean = 44), which persisted until day 360 (pooled mean = 10). Anti LPS IgG antibodies peaked on day 7 (pooled mean = 94). Thereafter, they decreased on day 30 (pooled mean = 85), and dropped further on days 90 (pooled mean = 51) and 180 (pooled mean = 47), and returned to baseline on day 360 (pooled mean = 32). Sensitivity analysis including data from young children (aged 2-5 years) showed very similar findings as in the primary analysis. Conclusions: This study confirms that serological antibody (vibriocidal, CTB, and LPS) titers return to baseline levels within 1 year following clinical cholera, i.e., before the protective immunity against subsequent cholera wanes. However, this decay should not be interpreted as waning immunity because immunity conferred by cholera against subsequent disease lasts 3-10 years. Our study provides evidence for surveillance strategies and future research on vaccines and also demonstrates the need for further studies to improve our understanding of immunity against cholera. en-copyright= kn-copyright= en-aut-name=MuzemboBasilua Andre en-aut-sei=Muzembo en-aut-mei=Basilua Andre kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KitaharaKei en-aut-sei=Kitahara en-aut-mei=Kei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MitraDebmalya en-aut-sei=Mitra en-aut-mei=Debmalya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OhnoAyumu en-aut-sei=Ohno en-aut-mei=Ayumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MiyoshiShin-Ichi en-aut-sei=Miyoshi en-aut-mei=Shin-Ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Collaborative Research Center of Okayama University for Infectious Diseases in India kn-affil= affil-num=4 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=cholera kn-keyword=cholera en-keyword=antibodies kn-keyword=antibodies en-keyword=vibriocidal kn-keyword=vibriocidal en-keyword=cholera toxin B kn-keyword=cholera toxin B en-keyword=lipopolysaccharide kn-keyword=lipopolysaccharide en-keyword=immunoglobulin kn-keyword=immunoglobulin en-keyword=immunity kn-keyword=immunity en-keyword=waning kn-keyword=waning END start-ver=1.4 cd-journal=joma no-vol=58 cd-vols= no-issue= article-no= start-page=124 end-page=136 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=202211 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Managements of sleep bruxism in adult: A systematic review en-subtitle= kn-subtitle= en-abstract= kn-abstract=This systematic review aimed to update the management of sleep bruxism (SB) in adults, as diagnosed using polysomnography (PSG) and/or electromyography (EMG). Management methods covered were oral appliance therapy (OAT) with stabilization splints, cognitive-behavioral therapy (CBT), biofeedback therapy (BFT), and pharmacological therapy. A comprehensive search was conducted on MEDLINE, Cochrane Library, and Web of Science up to October 1st, 2021. Reference list searches and hand searches were also performed by an external organization. Two reviewers for each therapy independently performed article selection, data extraction, and risk of bias assessment. The reviewers resolved any disagreements concerning the assortment of the articles by discussion. Finally, 11, 3, 14, and 22 articles were selected for each therapy. The results suggested that OAT tended to reduce the number of SB events, although there was no significant difference compared to other types of splints, that the potential benefits of CBT were not well supported, and that BFT, rabeprazole, clonazepam, clonidine, and botulinum toxin type A injection showed significant reductions in specific SB parameters, although several side effects were reported. It can be concluded that more methodologically rigorous randomized large-sample long-term follow-up clinical trials are needed to clarify the efficacy and safety of management for SB. en-copyright= kn-copyright= en-aut-name=MinakuchiHajime en-aut-sei=Minakuchi en-aut-mei=Hajime kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FujisawaMasanori en-aut-sei=Fujisawa en-aut-mei=Masanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AbeYuka en-aut-sei=Abe en-aut-mei=Yuka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=IidaTakashi en-aut-sei=Iida en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OkiKyosuke en-aut-sei=Oki en-aut-mei=Kyosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OkuraKazuo en-aut-sei=Okura en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=TanabeNorimasa en-aut-sei=Tanabe en-aut-mei=Norimasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NishiyamaAkira en-aut-sei=Nishiyama en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Oral Rehabilitation and Regenerative Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Division of Fixed Prosthodontics, Department of Restorative & Biomaterials Sciences, Meikai University School of Dentistry kn-affil= affil-num=3 en-affil=Department of Prosthodontics, School of Dentistry, Showa University kn-affil= affil-num=4 en-affil=Department of Oral Function and Fixed Prosthodontics, Nihon University School of Dentistry at Matsudo kn-affil= affil-num=5 en-affil=Section of Fixed Prosthodontics, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University kn-affil= affil-num=6 en-affil=Department of Stomatognathic Function and Occlusal Reconstruction, Institute of Biomedical Sciences, Tokushima University Graduate School kn-affil= affil-num=7 en-affil=Department of Prosthodontics and Oral Implantology, School of Dentistry, Iwate Medical University kn-affil= affil-num=8 en-affil=General Dentistry, Comprehensive Patient Care, Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University kn-affil= en-keyword=Sleep bruxism kn-keyword=Sleep bruxism en-keyword=Management kn-keyword=Management en-keyword=Systematic review kn-keyword=Systematic review en-keyword=Oral appliances kn-keyword=Oral appliances en-keyword=Biofeedback therapy kn-keyword=Biofeedback therapy en-keyword=Cognitive-behavioral therapy kn-keyword=Cognitive-behavioral therapy en-keyword=Pharmacological therapy kn-keyword=Pharmacological therapy END start-ver=1.4 cd-journal=joma no-vol=17 cd-vols= no-issue=4 article-no= start-page=e0267587 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220421 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Interest in Infectious Diseases specialty among Japanese medical students amidst the COVID-19 pandemic: A web-based, cross-sectional study en-subtitle= kn-subtitle= en-abstract= kn-abstract=IntroductionThe emergence of the novel coronavirus disease of 2019 (COVID-19) has led to huge disruptions in the medical field and society. The significance of training and education for experts has been increasingly acknowledged in Japan, where the number of infectious disease (ID) specialists is reportedly insufficient. In this paper, we report the results of a web-based survey that was conducted to reveal the ways in which the COVID-19 pandemic has influenced medical students' awareness of ID specialists and future career choices. MethodThis cross-sectional descriptive study was conducted in March 2021 and targeted 717 medical students belonging to Medical School of Okayama University, Japan. The questionnaire consisted of four questions meant to assess students' knowledge and future intentions of becoming ID specialists. ResultsWe obtained 328 eligible questionnaires (response rate: 45.7%). Of 227 (69.2%) students who were aware of ID specialists, 99 (43.6%) answered that they came to know about them only after the pandemic, 12 (3.7%) answered that their interest in being an ID specialist arose during the pandemic, while 36 (11.0%) responded that they would rather not become ID specialists. At the time of the survey, 5 students (1.5%) were aiming to become ID specialists. ConclusionWe observed a very low rate of interest to be an ID specialist among medical students. The experience of the pandemic does not seem to have influenced Japanese medical students to choose ID as a specialty for their careers. Continuous efforts to increase the number of ID specialists are necessary in Japan as a countermeasure against the coming pandemic. en-copyright= kn-copyright= en-aut-name=HagiyaHideharu en-aut-sei=Hagiya en-aut-mei=Hideharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OtsukaYuki en-aut-sei=Otsuka en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TokumasuKazuki en-aut-sei=Tokumasu en-aut-mei=Kazuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HondaHiroyuki en-aut-sei=Honda en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NishimuraYoshito en-aut-sei=Nishimura en-aut-mei=Yoshito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ObikaMikako en-aut-sei=Obika en-aut-mei=Mikako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=3 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=4 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=7 en-affil=Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= END start-ver=1.4 cd-journal=joma no-vol=19 cd-vols= no-issue=9 article-no= start-page=5738 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220508 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Cholera Outbreaks in India, 2011-2020: A Systematic Review en-subtitle= kn-subtitle= en-abstract= kn-abstract=Fecal contamination of water sources and open defecation have been linked to cholera outbreaks in India. However, a systematic review on the drivers responsible for these outbreaks has yet to be published. Here, we systematically review the published literature on cholera outbreaks in India between 2011 and 2020. We searched studies in English in three databases (MEDLINE, EMBASE, and Web of Science) and the Integrated Disease Surveillance Program that tracks cholera outbreaks throughout India. Two authors independently extracted data and assessed the quality of the included studies. Quantitative data on the modes of transmission reviewed in this study were assessed for any change over time between 2011-2015 and 2016-2020. Our search retrieved 10823 records initially, out of which 81 full-text studies were assessed for eligibility. Among these 81 studies, 20 were eligible for inclusion in this review. There were 565 reported outbreaks between 2011 and 2020 that led to 45,759 cases and 263 deaths. Outbreaks occurred throughout the year; however, they exploded with monsoons (June through September). In Tamil Nadu, a typical peak of cholera outbreaks was observed from December to January. Seventy-two percent (33,089/45,759) of outbreak-related cases were reported in five states, namely Maharashtra, West Bengal, Punjab, Karnataka, and Madhya Pradesh. Analysis of these outbreaks highlighted the main drivers of cholera including contaminated drinking water and food, inadequate sanitation and hygiene (including open defecation), and direct contact between households. The comparison between 2011-2015 and 2016-2020 showed a decreasing trend in the outbreaks that arose due to damaged water pipelines. Many Indians still struggle with open defecation, sanitation, and clean water access. These issues should be addressed critically. In addition, it is essential to interrupt cholera short-cycle transmission (mediated by households, stored drinking water and foodstuffs) during an outbreak. As cholera is associated with deprivation, socio-economic development is the only long-term solution. en-copyright= kn-copyright= en-aut-name=MuzemboBasilua Andre en-aut-sei=Muzembo en-aut-mei=Basilua Andre kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KitaharaKei en-aut-sei=Kitahara en-aut-mei=Kei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=DebnathAnusuya en-aut-sei=Debnath en-aut-mei=Anusuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OhnoAyumu en-aut-sei=Ohno en-aut-mei=Ayumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OkamotoKeinosuke en-aut-sei=Okamoto en-aut-mei=Keinosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MiyoshiShin-Ichi en-aut-sei=Miyoshi en-aut-mei=Shin-Ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=5 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=6 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= en-keyword=cholera kn-keyword=cholera en-keyword=outbreak kn-keyword=outbreak en-keyword=water supply kn-keyword=water supply en-keyword=open defecation kn-keyword=open defecation en-keyword=sewage kn-keyword=sewage en-keyword=household kn-keyword=household en-keyword=food kn-keyword=food en-keyword=close contact kn-keyword=close contact en-keyword=behavioral changes kn-keyword=behavioral changes en-keyword=India kn-keyword=India END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue= article-no= start-page=33 end-page=46 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An Investigation on “Ae” of Real-time Online Lecture at the Okayama university - Using the YouTube Live + OBS Studio and Google Classroom Web Applications kn-title=リアルタイムオンライン講義の受講効率の検証と課題 ―YouTube Live + OBS Studio とGoogle Classroom の活用― en-subtitle= kn-subtitle= en-abstract=Real-time online lecture were held at the Okayama University. The online system that used were constructed newly by the authors using the YouTube Live and Google classroom Web applications. This system could also provide a lecture video archive. The construction cost and operating cost of the system could be quite low. In addition to delivering lecture videos, the LMS was using for streamline communication with students. Lectures were never stopped due to a failure in the video delivery system or the LMS. The system freed the lecturer from the restrictions of lecture room facilities and lecture timetables, made it easier to use multimedia teaching materials and virtual teaching materials. It was also thought that the student's attendance efficiency was improved to about 2.9 times that of legacy lecture style. Verification of the qualitative problems of the lesson structure and contents, the deepening of students' understanding of the lesson contents, and the breakdown of the qualifications and abilities acquired by t he students are future t asks. kn-abstract=岡山大学でリアルタイムオンライン講義を実施した。使用したオンラインシステムはYouTubeLiveとGoogleClassroomのWebアプリケーションを使用して作成者が新たに構築した。このシステムは，講義ビデオアーカイブを提供することも可能であった。システムの構築費と運用費はかなり低くなる可能性がある。LMSは，講義ビデオの配信に加えて，学生とのコミュニケーションを合理化するために用いた。ビデオ配信システムまたはLMSの障害が原因でオンライン講義が停止することはなかった。このシステムにより講師は講義室の設備や講義の時間割の制約から解放され，マルチメディア教材やバーチャル教材の使用が容易になった。また学生の受講効率は従来の講義形式に対して約2.9倍に向上したと考えられる。授業の構成や内容の質的問題の検証，授業内容に対する生徒の理解の深化，生徒が習得した資質や能力の内容の検証は今後の課題である。 en-copyright= kn-copyright= en-aut-name=YamakawaJunji en-aut-sei=Yamakawa en-aut-mei=Junji kn-aut-name=山川純次 kn-aut-sei=山川 kn-aut-mei=純次 aut-affil-num=1 ORCID= en-aut-name=TakahataHiroshi en-aut-sei=Takahata en-aut-mei=Hiroshi kn-aut-name=旗浩志 kn-aut-sei=旗 kn-aut-mei=浩志 aut-affil-num=2 ORCID= affil-num=1 en-affil=Academic Field of Natural Science a nd Technology, Okayama University kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil=Center for Teacher Education and Development, Okayama University kn-affil=岡山大学教師教育開発センター en-keyword=オンライン講義(Online Lecture) kn-keyword=オンライン講義(Online Lecture) en-keyword=OBS Studio kn-keyword=OBS Studio en-keyword=YouTube Live kn-keyword=YouTube Live en-keyword=Google Classroom kn-keyword=Google Classroom en-keyword=受講効率(Attendance efficiency) kn-keyword=受講効率(Attendance efficiency) END start-ver=1.4 cd-journal=joma no-vol=179 cd-vols= no-issue= article-no= start-page=1 end-page=14 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220224 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Verification of Learning Outcomes in Professional School for Teacher Education of Okayama University: A Follow-up Survey of In-service Student Graduates kn-title=岡山大学教職大学院における学修の成果とその活用の検証― 現職学生修了生へのフォローアップ調査の結果報告 ― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本研究では，岡山大学教職大学院の現職学生修了生及びその勤務先所属長に対して調査を行い，教職大学院での学修の成果が学校教育活動においてどのように活かされているか，また教員としてのどのような資質・能力の伸長につながったのかを検討した。修了生及びその勤務先所属長から得られたWebアンケートへの回答の集計・分析の結果から，大半の修了生が教職大学院での学びを現在の仕事で活用できており，所属長からも高い評価を得ていることが確認された。一方で，修了生は教科の学習評価の観点や方法，新しい教育課題へ対応するための力を伸長する必要性を認識していた。また所属長は，より広い視野に立って学校のあり方や教育実践をとらえ，個別の児童生徒の抱える課題や新たな教育課題に対する全校的な教育支援体制を構築し改善する力を備えた，スクールリーダーとしての成長を期待していた。本研究で得られた示唆を踏まえ，今後は教職大学院の教育課程と授業に係る課題の抽出とその改善を図るとともに，修了生へのフォローアップの機会の提供など，学修成果の質を高める手立てを継続的に検討していく必要がある。 en-copyright= kn-copyright= en-aut-name=AKAGIKyogo en-aut-sei=AKAGI en-aut-mei=Kyogo kn-aut-name=赤木恭吾 kn-aut-sei=赤木 kn-aut-mei=恭吾 aut-affil-num=1 ORCID= en-aut-name=HATTORIYasumasa en-aut-sei=HATTORI en-aut-mei=Yasumasa kn-aut-name=服部康正 kn-aut-sei=服部 kn-aut-mei=康正 aut-affil-num=2 ORCID= en-aut-name=MISAWARyo en-aut-sei=MISAWA en-aut-mei=Ryo kn-aut-name=三沢良 kn-aut-sei=三沢 kn-aut-mei=良 aut-affil-num=3 ORCID= en-aut-name=KANAGAWAMakiko en-aut-sei=KANAGAWA en-aut-mei=Makiko kn-aut-name=金川舞貴子 kn-aut-sei=金川 kn-aut-mei=舞貴子 aut-affil-num=4 ORCID= affil-num=1 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=2 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=3 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 affil-num=4 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学学術研究院教育学域 en-keyword=教師教育 kn-keyword=教師教育 en-keyword=教職大学院 kn-keyword=教職大学院 en-keyword=学修の成果 kn-keyword=学修の成果 en-keyword=現職学生 kn-keyword=現職学生 en-keyword=フォローアップ調査 kn-keyword=フォローアップ調査 END start-ver=1.4 cd-journal=joma no-vol=9 cd-vols= no-issue= article-no= start-page=111651 end-page=111665 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=2021 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Mitigation of Kernel Memory Corruption Using Multiple Kernel Memory Mechanism en-subtitle= kn-subtitle= en-abstract= kn-abstract=Operating systems adopt kernel protection methods (e.g., mandatory access control, kernel address space layout randomization, control flow integrity, and kernel page table isolation) as essential countermeasures to reduce the likelihood of kernel vulnerability attacks. However, kernel memory corruption can still occur via the execution of malicious kernel code at the kernel layer. This is because the vulnerable kernel code and the attack target kernel code or kernel data are located in the same kernel address space. To gain complete control of a host, adversaries focus on kernel code invocations, such as function pointers that rely on the starting points of the kernel protection methods. To mitigate such subversion attacks, this paper presents multiple kernel memory (MKM), which employs an alternative design for kernel address space separation. The MKM mechanism focuses on the isolation granularity of the kernel address space during each execution of the kernel code. MKM provides two kernel address spaces, namely, i) the trampoline kernel address space, which acts as the gateway feature between user and kernel modes and ii) the security kernel address space, which utilizes the localization of the kernel protection methods (i.e., kernel observation). Additionally, MKM achieves the encapsulation of the vulnerable kernel code to prevent access to the kernel code invocations of the separated kernel address space. The evaluation results demonstrated that MKM can protect the kernel code and kernel data from a proof-of-concept kernel vulnerability that could lead to kernel memory corruption. In addition, the performance results of MKM indicate that the system call overhead latency ranges from 0.020 μs to 0.5445 μs, while the web application benchmark ranges from 196.27 μs to 6, 685.73 μs for each download access of 100,000 Hypertext Transfer Protocol sessions. MKM attained a 97.65% system benchmark score and a 99.76% kernel compilation time. en-copyright= kn-copyright= en-aut-name=KuzunoHiroki en-aut-sei=Kuzuno en-aut-mei=Hiroki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=1Intelligent Systems Laboratory, SECOM Company Ltd. kn-affil= affil-num=2 en-affil=2Graduate School of Natural Science and Technology, Okayama University kn-affil= en-keyword=Memory corruption kn-keyword=Memory corruption en-keyword=kernel vulnerability kn-keyword=kernel vulnerability en-keyword=system security kn-keyword=system security en-keyword=operating system kn-keyword=operating system END start-ver=1.4 cd-journal=joma no-vol=52 cd-vols= no-issue= article-no= start-page=195 end-page=212 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20211224 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Labor Value and Job Satisfaction Analysis of Young Employees: The Perspective of Internal Marketing kn-title=若手社員の労働価値観と職務満足分析： インターナル・マーケティングの視点 en-subtitle= kn-subtitle= en-abstract=In this study, we conducted a web survey of young employees up to the third year after graduating from university using questionnaire survey, and analyzed the factors that labor values affect job satisfaction. We used CS analysis used in customer satisfaction surveys. The priority maintenance items with high satisfaction were task identity, social contribution, and sense of accomplishment (work), and the top priority improvement items with high improvement were dedication (organization), devoted (organization), and organizational contribution. In the future, it is necessary to incorporate five job characteristic factors that make the work originally interesting. In addition, job design that raises MPS (Motivating Potential Score) to increase the degree of intrinsic motivation becomes important. For managers and human resources personnel, understanding and improving the labor values of young employees will lead to job satisfaction of young employees, and the turnover rate will decrease. As laborer values change due to corona disaster, an internal marketing erspective is required to create the attractive work that young employees demand. kn-abstract=本研究は、大学卒業後、入社3年目までの若手社員を対象に質問紙調紙を用いてweb調査を実施し、労働価値観が職務満足に及ぼす要因を分析した。顧客満足度調査などで用いられるCS分析を活用した。満足度が高い重点維持項目は、タスクの完結性、達成感（仕事）、社会貢献となり、改善度が高い重点改善項目は、捧げる（組織）、尽くす（組織）、組織貢献となった。今後、若手社員の職務満足を高めていくには、仕事本来の面白さを感じる5つの職務特性要因を仕事に取り入れていく必要がある。また、内発的モチベーションの度合を図るMPS（Motivating Potential Score）を高めていく、職務設計が重要になってくる。経営者や人事担当者は、若手社員の労働価値観を理解して改善していくことが、若手社員の職務満足につながり、離職率の低下となっていく。コロナ禍で労働価値観が変化するなか、若手社員が求める働く魅力づくりをしていくには、インターナル・マーケティングの視点が求められる。 en-copyright= kn-copyright= en-aut-name=NIGOShouji en-aut-sei=NIGO en-aut-mei=Shouji kn-aut-name=児子正治 kn-aut-sei=児子 kn-aut-mei=正治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院社会文化科学研究科 en-keyword=職務満足 kn-keyword=職務満足 en-keyword=労働価値観 kn-keyword=労働価値観 en-keyword=インターナル・マーケティング kn-keyword=インターナル・マーケティング en-keyword=職務特性要因 kn-keyword=職務特性要因 en-keyword=MPS kn-keyword=MPS END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=4 article-no= start-page=431 end-page=437 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=202108 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Differences in Attitudes and Practices of Cancer Pain Management between Medical Oncologists and Palliative Care Physicians en-subtitle= kn-subtitle= en-abstract= kn-abstract=This study aimed to evaluate whether there are differences in the attitudes and practices of cancer pain manage-ment between medical oncologists and palliative care physicians. An online nationwide survey was used to collect responses from board-certified medical oncologists and palliative care physicians in Japan. The survey questionnaire comprised 30 questions. The differences in responses between medical oncologists and palliative care physicians were examined. Out of the 1,227 questionnaires sent, 522 (42.5%) were returned. After apply-ing the exclusion criteria, 445 questionnaires (medical oncologists: n = 283; palliative care physicians: n = 162) were retained for analysis. Among the questions about potential barriers to optimal cancer pain man-agement, both medical oncologists and palliative care physicians considered the reluctance of patients to take opioids due to fear of adverse effects as the greatest barrier. Significantly different ratings between medical oncologists and palliative care physicians were observed on 5 of the 8 questions in this area. Significantly differ-ent ratings were observed for all questions concerning pain specialists and their knowledge. For effective cancer pain management, it is important to account for differences in attitudes and practice between medical oncolo-gists and palliative care physicians. en-copyright= kn-copyright= en-aut-name=KunitomiToshiki en-aut-sei=Kunitomi en-aut-mei=Toshiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NasuJunichirou en-aut-sei=Nasu en-aut-mei=Junichirou kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MinamiDaisuke en-aut-sei=Minami en-aut-mei=Daisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=IwamotoTakayuki en-aut-sei=Iwamoto en-aut-mei=Takayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NishieHiroyuki en-aut-sei=Nishie en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SaitoShinya en-aut-sei=Saito en-aut-mei=Shinya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=MatsuokaJunji en-aut-sei=Matsuoka en-aut-mei=Junji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Internal Medicine, Okayama Saiseikai General Hospital kn-affil= affil-num=3 en-affil=Palliative Care Team, Okayama University Hospital kn-affil= affil-num=4 en-affil=Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=5 en-affil=Palliative Care Team, Okayama University Hospital kn-affil= affil-num=6 en-affil=Palliative Care Team, Okayama University Hospital kn-affil= affil-num=7 en-affil=Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=8 en-affil=Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= en-keyword=cancer pain management kn-keyword=cancer pain management en-keyword=opioid kn-keyword=opioid en-keyword=medical oncologist kn-keyword=medical oncologist en-keyword=palliative care physician kn-keyword=palliative care physician en-keyword=barriers kn-keyword=barriers END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=20489448 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=202011 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Method of Generating a Blacklist for Mobile Devices by Searching Malicious Websites en-subtitle= kn-subtitle= en-abstract= kn-abstract=As mobile devices have become more popular, malware and attacks directed at them have significantly increased. One of the methods to attack mobile devices is redirecting a user to unwanted websites by unwanted page transition. One of the countermeasures against such attacks is to generate a blacklist of URLs and hostnames, which can prevent access to malicious websites. To generate a blacklist, first, malicious websites are collected in the web space. Then, URLs and hostnames of the malicious websites are added to the blacklist. However, URLs of the malicious websites are typically changed frequently; thus, it is necessary to keep track of the malicious websites and update the blacklist in a timely manner. In this study, we proposed a method to generate blacklists for mobile devices by searching malicious websites. The method collects many HTML files from the web space using a crawler and searches for HTML files that are highly likely to be malicious using keywords extracted from the known malicious websites to discover the new ones. Thus, new malicious websites can be added to the blacklist in a timely manner. Using the proposed method, we discovered malicious websites that were not detected by Google Safe Browsing. Moreover, the blacklist generated using the method had a high detection rate for certain malicious websites. This paper reports the design process and the results of the evaluation of the new method. en-copyright= kn-copyright= en-aut-name=IshiharaTakashi en-aut-sei=Ishihara en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SatoMasaya en-aut-sei=Sato en-aut-mei=Masaya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= en-keyword=Malicious Websites kn-keyword=Malicious Websites en-keyword=Blacklist kn-keyword=Blacklist en-keyword=Web-based Attack kn-keyword=Web-based Attack en-keyword=Android kn-keyword=Android END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=1 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2018 dt-pub=2018129 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Web access monitoring mechanism for Android webview en-subtitle= kn-subtitle= en-abstract= kn-abstract=In addition to conventional web browsers, WebView is used to display web content on Android. WebView is a component that enables the display of web content in mobile applications, and is extensively used. As WebView displays web content without having to redirect the user to web browsers, there is the possibility that unauthorized web access may be performed secretly via Web-View, and information in Android may be stolen or tampered with. Therefore, it is necessary to monitor and analyze web access via WebView, particularly because attacks exploiting WebView have been reported. However, there is no mechanism for monitoring web access viaWebView. In this work, the goals are to monitor web access via WebView and to analyze mobile applications using Web-View. To achieve these goals, we propose a web access monitoring mechanism for Android WebView. In this paper, the design and implementation of a mechanism that does not require any modifications to the Android Framework and Linux kernel are presented for the Chromium Android System WebView app. In addition, this paper presents evaluation results for the proposed mechanism. en-copyright= kn-copyright= en-aut-name=ImamuraYuta en-aut-sei=Imamura en-aut-mei=Yuta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=UekawaHiroyuki en-aut-sei=Uekawa en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IshiharaYasuhiro en-aut-sei=Ishihara en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SatoMasaya en-aut-sei=Sato en-aut-mei=Masaya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Okayama University, Okayama, Japan kn-affil= affil-num=2 en-affil=Okayama University, Okayama, Japan kn-affil= affil-num=3 en-affil=Okayama University, Okayama, Japan kn-affil= affil-num=4 en-affil=Okayama University, Okayama, Japan kn-affil= affil-num=5 en-affil=Okayama University Okayama, Japan kn-affil= en-keyword=Android kn-keyword=Android en-keyword= WebView kn-keyword= WebView en-keyword=Web access monitoring kn-keyword=Web access monitoring END start-ver=1.4 cd-journal=joma no-vol=26 cd-vols= no-issue= article-no= start-page=396 end-page=405 dt-received= dt-revised= dt-accepted= dt-pub-year=2018 dt-pub=2018 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Access Control Mechanism to Mitigate Cordova Plugin Attacks in Hybrid Applications en-subtitle= kn-subtitle= en-abstract= kn-abstract=Hybrid application frameworks such as Cordova are more and more popular to create platform-independent applications (apps) because they provide special APIs to access device resources in a platform-agonistic way. By using these APIs, hybrid apps can access device resources through JavaScript. In this paper, we present a novel app-repackaging attack that repackages hybrid apps with malicious code; this code can exploit Cordova's plugin interface to steal and tamper with device resources. We address this attack and cross-site scripting attacks against hybrid apps. Since these attacks need to use plugins to access device resources, we refer to both of these attacks as Cordova plugin attacks. We further demonstrate a defense against Cordova plugin attacks through the use of a novel runtime access control mechanism that restricts access based on the mobile user's judgement. Our mechanism is easy to introduce to existing Cordova apps, and allows developers to produce apps that are resistant to Cordova plugin attacks. Moreover, we evaluate the effectiveness and performance of our mechanism. en-copyright= kn-copyright= en-aut-name=KudoNaoki en-aut-sei=Kudo en-aut-mei=Naoki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AustinThomas H. en-aut-sei=Austin en-aut-mei=Thomas H. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=San Jose State University kn-affil= en-keyword=hybrid Application kn-keyword=hybrid Application en-keyword=Android kn-keyword=Android en-keyword=Access Control kn-keyword=Access Control END start-ver=1.4 cd-journal=joma no-vol=24 cd-vols= no-issue=5 article-no= start-page=781 end-page=792 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160915 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Design of Function for Tracing Diffusion of Classified Information for IPC on KVM en-subtitle= kn-subtitle= en-abstract= kn-abstract=The leaking of information has increased in recent years. To address this problem, we previously proposed a function for tracing the diffusion of classified information in a guest OS using a virtual machine monitor (VMM). This function makes it possible to grasp the location of classified information and detect information leakage without modifying the source codes of the guest OS. The diffusion of classified information is caused by the file operation, child process creation, and inter-process communication (IPC). In a previous study, we implemented the proposed function for a file operation and child process creation excluding IPC using a kernel-based virtual machine (KVM). In this paper, we describe the design of the proposed function for IPC on a KVM without modifying the guest OS. The proposed function traces the local and remote IPCs inside the guest OS from the outside so as to trace the information diffusion. Because IPC with an outside computer might cause an information leakage, tracing the IPCs enables the detection of such a leakage. We also report the evaluation results including the traceability and performance of the proposed function. en-copyright= kn-copyright= en-aut-name=FujiiShota en-aut-sei=Fujii en-aut-mei=Shota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SatoMasaya en-aut-sei=Sato en-aut-mei=Masaya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TaniguchiHideo en-aut-sei=Taniguchi en-aut-mei=Hideo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= en-keyword=Information Leakage Prevention kn-keyword=Information Leakage Prevention en-keyword=Inter-Process Communication kn-keyword=Inter-Process Communication en-keyword=Virtualization kn-keyword=Virtualization END start-ver=1.4 cd-journal=joma no-vol=2021 cd-vols= no-issue= article-no= start-page=8883946 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210806 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Accuracy of Deep Learning Algorithms for the Diagnosis of Retinopathy of Prematurity by Fundus Images: A Systematic Review and Meta-Analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background. Retinopathy of prematurity (ROP) occurs in preterm infants and may contribute to blindness. Deep learning (DL) models have been used for ophthalmologic diagnoses. We performed a systematic review and meta-analysis of published evidence to summarize and evaluate the diagnostic accuracy of DL algorithms for ROP by fundus images.
Methods. We searched PubMed, EMBASE, Web of Science, and Institute of Electrical and Electronics Engineers Xplore Digital Library on June 13, 2021, for studies using a DL algorithm to distinguish individuals with ROP of different grades, which provided accuracy measurements. ,e pooled sensitivity and specificity values and the area under the curve (AUC) of summary receiver operating characteristics curves (SROC) summarized overall test performance. ,e performances in validation and test datasets were assessed together and separately. Subgroup analyses were conducted between the definition and grades of ROP. ,reshold and nonthreshold effects were tested to assess biases and evaluate accuracy factors associated with DL models.
Results. Nine studies with fifteen classifiers were included in our meta-analysis. A total of 521,586 objects were applied to DL models. For combined validation and test datasets in each study, the pooled sensitivity and specificity were 0.953 (95% confidence intervals (CI): 0.946?0.959) and 0.975 (0.973?0.977), respectively, and the AUC was 0.984 (0.978?0.989). For the validation dataset and test dataset, the AUC was 0.977 (0.968?0.986) and 0.987 (0.982?0.992), respectively. In the subgroup analysis of ROP vs. normal and differentiation of two ROP grades, the AUC was 0.990 (0.944?0.994) and 0.982 (0.964?0.999), respectively.
Conclusions. Our study shows that DL models can play an essential role in detecting and grading ROP with high sensitivity, specificity, and repeatability. ,e application of a DL-based automated system may improve ROP screening and diagnosis in the future. en-copyright= kn-copyright= en-aut-name=ZhangJingjing en-aut-sei=Zhang en-aut-mei=Jingjing kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=LiuYangyang en-aut-sei=Liu en-aut-mei=Yangyang kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MitsuhashiToshiharu en-aut-sei=Mitsuhashi en-aut-mei=Toshiharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MatsuoToshihiko en-aut-sei=Matsuo en-aut-mei=Toshihiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Regenerative and Reconstructive Medicine (Ophthalmology), Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= affil-num=2 en-affil=Department of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil= affil-num=3 en-affil=Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama University kn-affil= affil-num=4 en-affil=Department of Regenerative and Reconstructive Medicine (Ophthalmology), Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=970 cd-vols= no-issue= article-no= start-page=609 end-page=620 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=201967 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Cross-Cultural Analysis of Top Page Design Among Brazilian, Chinese, Japanese and United States Web Sites en-subtitle= kn-subtitle= en-abstract= kn-abstract=The aim of present study was to reveal the differences of web design including cultural preference among the four countries that have different cultures. Twenty local municipal sites were randomly chosen from United States, Japan, China, and Brazil. The characteristics of these web sites was investigated from viewpoint of the following seven categories: (1) text, (2) layout, (3) navigation, (4) multimedia, (5) links, (6) items location, (7) color. When the web site had each factor, the researcher gave a "1" for that factor. Chi-square goodness-of-fit test was performed to compare the percentage of "0" or "1" of each factor among the four countries. Additionally, the correspondence analysis was performed to grasp the characteristics of each country. The characteristics of the top page design of the four countries were grasped based on these analyses. en-copyright= kn-copyright= en-aut-name=DoiToshihisa en-aut-sei=Doi en-aut-mei=Toshihisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MurataAtsuo en-aut-sei=Murata en-aut-mei=Atsuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil= affil-num=2 en-affil= kn-affil= en-keyword=Web design kn-keyword=Web design en-keyword=Cultural difference kn-keyword=Cultural difference en-keyword=Appearance kn-keyword=Appearance en-keyword=Cultural usability kn-keyword=Cultural usability END start-ver=1.4 cd-journal=joma no-vol=17 cd-vols= no-issue=2 article-no= start-page=140 end-page=152 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=202145 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A proposal of recommendation function for element fill-in-Blank problems in java programming learning assistant system en-subtitle= kn-subtitle= en-abstract= kn-abstract=Purpose
To advance Java programming educations, the authors have developed a Web-based Java programming learning assistant system (JPLAS). It offers the element fill-in-blank problem (EFP) for novice students to study Java grammar and basic programming skills by filling in the missing elements in a source code. An EFP instance can be generated by selecting an appropriate code, and applying the blank element selection algorithm. As it is expected to cover broad grammar topics, a number of EFP instances have been generated. This paper aims to propose a recommendation function to guide a student solving the proper EFP instances among them.

Design/methodology/approach
This function considers the difficulty level of the EFP instance and the grammar topics that have been correctly answered by the student, and is implemented at the offline answering function of JPLAS using JavaScript so that students can use it even without the Internet connections.

Findings
To evaluate the effectiveness of the proposal, 85 EFP instances are prepared to cover various grammar topics, and are assigned to a total of 92 students in two universities in Myanmar and Indonesia to solve them using the recommendation function. Their solution results confirmed the effectiveness of the proposal.

Originality/value
The concept of the difficulty level for an EFP instance is newly defined for the proper recommendation, and the accuracy in terms of the average numbers of answer submission times among the students is verified. en-copyright= kn-copyright= en-aut-name=WintSu Sandy en-aut-sei=Wint en-aut-mei=Su Sandy kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SyaifudinYan Watequlis en-aut-sei=Syaifudin en-aut-mei=Yan Watequlis kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AungShune Lae en-aut-sei=Aung en-aut-mei=Shune Lae kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KaoWen-Chun en-aut-sei=Kao en-aut-mei=Wen-Chun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=2 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=3 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=4 en-affil=Department of Computer Studies, University of Yangon kn-affil= affil-num=5 en-affil=Department of Electrical Engineering, National Taiwan Normal University kn-affil= en-keyword=JavaScript kn-keyword=JavaScript en-keyword=Java programming kn-keyword=Java programming en-keyword=JPLAS kn-keyword=JPLAS en-keyword=Element fill-in-blank problem kn-keyword=Element fill-in-blank problem en-keyword=Offline answering function kn-keyword=Offline answering function en-keyword=Recommendation function kn-keyword=Recommendation function END start-ver=1.4 cd-journal=joma no-vol=1 cd-vols= no-issue= article-no= start-page=47 end-page=63 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Information and communication technology equipment and services for remote monitoring and health management: Survey of services and their classification for use in home care nursing kn-title=遠隔での見守りのための機器・サービスの調査と訪問看護での利用を想定した分類 en-subtitle= kn-subtitle= en-abstract= kn-abstract=This study aims to improve the quality of home nursing care for the elderly. The report presents web-based information about devices and services for remote monitoring and health management using information and communication technology and about how they can improve home care nursing station efficiency in Japan. The search terms "elderly people," "watch over," and "service," plus "sensor" were used to narrow the search. After repeating the search using a chained search for materials and links extracted from those search results, services for home care stations particularly addressing the remote monitoring of elderly people were selected and extracted. Early detection of abnormalities for support by home health nurse responsibilities for observing the general condition of the patient was chosen as the main evaluation index of usefulness. The contractor and service cost were secondary evaluation axes. Results show 9 information communication devices and services for real-time monitoring of the elderly persons’ vital signs in real time for 24 hr, 2 of which are highly useful for early detection of abnormalities and subsequent response. Results suggest that other services might be more useful, depending on how they are used, and that general-purpose services with minimum functions and low cost of introduction and maintenance can provide more opportunities for utilization. Providing these services on a BtoBtoC model and responding to patients’ medical needs can supplement home care nursing station work, increase human resource and time efficiencies, and give patients "the feeling that a nurse is always at their bedside,” even when far away. en-copyright= kn-copyright= en-aut-name=SakamotoToshio en-aut-sei=Sakamoto en-aut-mei=Toshio kn-aut-name=坂本年生 kn-aut-sei=坂本 kn-aut-mei=年生 aut-affil-num=1 ORCID= en-aut-name=HirataAkina en-aut-sei=Hirata en-aut-mei=Akina kn-aut-name=平田晶奈 kn-aut-sei=平田 kn-aut-mei=晶奈 aut-affil-num=2 ORCID= en-aut-name=MoritaMizuki en-aut-sei=Morita en-aut-mei=Mizuki kn-aut-name=森田瑞樹 kn-aut-sei=森田 kn-aut-mei=瑞樹 aut-affil-num=3 ORCID= affil-num=1 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil=岡山大学大学院ヘルスシステム統合科学研究科 affil-num=2 en-affil=Yell Co., Ltd. kn-affil=株式会社エール affil-num=3 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil=岡山大学大学院ヘルスシステム統合科学研究科 en-keyword=elderly people kn-keyword=elderly people en-keyword=watch over kn-keyword=watch over en-keyword=sensor kn-keyword=sensor en-keyword=in home care support kn-keyword=in home care support en-keyword=telenursing kn-keyword=telenursing END start-ver=1.4 cd-journal=joma no-vol=1 cd-vols= no-issue= article-no= start-page=29 end-page=45 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Consideration about recognition of factors causing lack of confirmation in the nursing scene kn-title=看護場?における確認不?を引き起こす要因の認識に関する検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In the work process of nurses with high risk, it is very urgent to take countermeasures against the “lack of confirmation” of the main factors. Therefore, the purpose of this study is to clarify the details of the factors leading to the lack of confirmation, grasp the number of near misses, and to explore what kind of factors the individual characteristics of the nurse who acts as a stopper. We recruited 500 nurses on the Web and asked about the frequency of near misses due to lack of confirmation, the awareness of the causes of lack of confirmation, self-evaluation of stoppers, and the reasons why near misses did not lead to accidents. As a result, three factors were extracted regarding the recognition of the factors of lack of confirmation: "lack of consciousness", "inability to concentrate", and "lack of knowledge / experience". Three factors were extracted for self-evaluation of stopper characteristics: "awareness," "verification," and "cautiousness". In order to reduce the lack of confirmation, it is necessary to secure and allocate appropriate personnel and create an environment where treatment can be concentrated. Nurses should also raise knowledge and the awareness of the importance of confirmation. In addition, it is necessary to improve the clinical judgment of new nurses in order to prevent near misses. And it is thought that new nurses will become more confident by accumulating experience and affirming their abilities from their superiors, seniors and colleagues. en-copyright= kn-copyright= en-aut-name=ZuoWanxin en-aut-sei=Zuo en-aut-mei=Wanxin kn-aut-name=左婉馨 kn-aut-sei=左 kn-aut-mei=婉馨 aut-affil-num=1 ORCID= en-aut-name=HyodoYoshimi en-aut-sei=Hyodo en-aut-mei=Yoshimi kn-aut-name=兵藤好美 kn-aut-sei=兵藤 kn-aut-mei=好美 aut-affil-num=2 ORCID= en-aut-name=TanakaTomoko en-aut-sei=Tanaka en-aut-mei=Tomoko kn-aut-name=?中共? kn-aut-sei=?中 kn-aut-mei=共? aut-affil-num=3 ORCID= en-aut-name=GofukuAkio en-aut-sei=Gofuku en-aut-mei=Akio kn-aut-name=五福明夫 kn-aut-sei=五福 kn-aut-mei=明夫 aut-affil-num=4 ORCID= affil-num=1 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil=岡山大学大学院ヘルスシステム統合科学研究科 affil-num=2 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil=岡山大学ヘルスシステム統合科学研究科 affil-num=3 en-affil=Graduate School of Humanities and Social Sciences, Okayama University kn-affil=岡山大学大学院社会文化科学研究科 affil-num=4 en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University kn-affil=岡山大学大学院ヘルスシステム統合科学研究科 en-keyword=lack of confirmation kn-keyword=lack of confirmation en-keyword=stoppers kn-keyword=stoppers en-keyword=nurse kn-keyword=nurse END start-ver=1.4 cd-journal=joma no-vol=39 cd-vols= no-issue=3 article-no= start-page=180 end-page=190 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Catalog of prognostic tissue-based biomarkers in patients treated with neoadjuvant systemic therapy for urothelial carcinoma of the bladder: a systematic review en-subtitle= kn-subtitle= en-abstract= kn-abstract=PURPOSE
The present systematic review aimed to identify prognostic values of tissue-based biomarkers in patients treated with neoadjuvant systemic therapy (NAST), including chemotherapy (NAC) and checkpoint inhibitors (NAI) for urothelial carcinoma of the bladder (UCB).
MATERIAL AND METHODS
The PubMed, Web of Science, and Scopus databases were searched in August 2020 according to the PRISMA statement. Studies were deemed eligible if they compared oncologic or pathologic outcomes in patients treated with NAST for UCB with and without detected pretreatment tissue-based biomarkers.
RESULTS
Overall, 44 studies met our eligibility criteria. Twenty-three studies used immunohistochemistry (IHC), 19 ? gene expression analysis, three - quantitative polymerase chain reaction (QT PCR), and two ? next-generation sequencing (NGS). According to the currently available literature, predictive IHC-assessed biomarkers, such as receptor tyrosine kinases and DNA repair pathway alterations, do not seem to convincingly improve our prediction of pathologic response and oncologic outcomes after NAC. Luminal and basal tumor subtypes based on gene expression analysis showed better NAC response, while claudin-low and luminal-infiltrated tumor subtypes did not. In terms of NAI, PD-L1 seems to maintain value as a predictive biomarker, while the utility of both tumor mutational burden and molecular subtypes remains controversial. Specific genomic alterations in DNA repair genes have been shown to provide significant predictive value in patient treated with NAC. QT PCR quantification of specific genes selected through microarray analysis seems to classify cases regarding their NAC response.
CONCLUSION
We believe that the present systematic review may offer a robust framework that will enable the testing and validation of predictive biomarkers in future prospective clinical trials. NGS has expanded the discovery of molecular markers that are reflective of the mechanisms of the NAST response. en-copyright= kn-copyright= en-aut-name=LaukhtinaEkaterina en-aut-sei=Laukhtina en-aut-mei=Ekaterina kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=PradereBenjamin en-aut-sei=Pradere en-aut-mei=Benjamin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MoriKeiichiro en-aut-sei=Mori en-aut-mei=Keiichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SchuettfortVictor M. en-aut-sei=Schuettfort en-aut-mei=Victor M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=QuhalFahad en-aut-sei=Quhal en-aut-mei=Fahad kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MostafaeiHadi en-aut-sei=Mostafaei en-aut-mei=Hadi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=Sari MotlanghReza en-aut-sei=Sari Motlangh en-aut-mei=Reza kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KatayamaSatoshi en-aut-sei=Katayama en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=GrossmannNico C. en-aut-sei=Grossmann en-aut-mei=Nico C. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=MoschiniMarco en-aut-sei=Moschini en-aut-mei=Marco kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=EnikeevDmitry en-aut-sei=Enikeev en-aut-mei=Dmitry kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=ShariatShahrokh F. en-aut-sei=Shariat en-aut-mei=Shahrokh F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= affil-num=1 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=2 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=3 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=4 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=5 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=6 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=7 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=8 en-affil=Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=9 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= affil-num=10 en-affil=Department of Urology, Luzerner Kantonsspital kn-affil= affil-num=11 en-affil=Institute for Urology and Reproductive Health, Sechenov University, kn-affil= affil-num=12 en-affil=Department of Urology, Comprehensive Cancer Center, Medical University of Vienna kn-affil= en-keyword=Biomarkers kn-keyword=Biomarkers en-keyword=UCB kn-keyword=UCB en-keyword=bladder cancer kn-keyword=bladder cancer en-keyword=Neoadjuvant systemic therapy kn-keyword=Neoadjuvant systemic therapy en-keyword=NAC kn-keyword=NAC en-keyword=systematic review kn-keyword=systematic review END start-ver=1.4 cd-journal=joma no-vol=5 cd-vols= no-issue= article-no= start-page=271 end-page=282 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20201230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Development of Placement Test Questions in Moodle for the Japanese Language Course kn-title=全学日本語コースのためのMoodleによる プレースメントテストの問題作成 en-subtitle= kn-subtitle= en-abstract= kn-abstract=岡山大学の全学日本語コースは現在，「全学日本語コースWebシステム」という独自のシステムを用いて，学内限定でオンラインによるプレースメントテストを行っている。このシステムの廃止が予定されていること，COVID-19の影響で学内への立ち入り制限が想定されることから，現システムに代わって学外からでも受験できる手段の準備が望まれている。そこで一つの解決策としてMoodleを用いたプレースメントテストの問題作成に取り組んだ。本稿ではMoodleによる聴解テストと文法テストの作成について紹介するとともに，今後の課題を述べる。 en-copyright= kn-copyright= en-aut-name=Yukako en-aut-sei= en-aut-mei=Yukako kn-aut-name=内丸裕佳子 kn-aut-sei=内丸 kn-aut-mei=裕佳子 aut-affil-num=1 ORCID= en-aut-name=SUWAMuneue en-aut-sei=SUWA en-aut-mei=Muneue kn-aut-name=諏訪棟植 kn-aut-sei=諏訪 kn-aut-mei=棟植 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil= affil-num=2 en-affil= kn-affil=岡山大学工学部機械システム系学科 en-keyword=プレースメントテスト kn-keyword=プレースメントテスト en-keyword=Moodle kn-keyword=Moodle en-keyword=全学日本語コースWebシステム kn-keyword=全学日本語コースWebシステム END start-ver=1.4 cd-journal=joma no-vol=5 cd-vols= no-issue= article-no= start-page=257 end-page=270 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20201230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Revision of Japanese Language Course Web System at Okayama University Associated with the Curriculum Change kn-title=カリキュラム変更に伴う 岡山大学全学日本語コースWebシステムの改訂 en-subtitle= kn-subtitle= en-abstract= kn-abstract=岡山大学では留学生用全学日本語コースの履修登録や成績入力は大学の履修登録システムに組み込まれていない。そのため，教員が主体となり，2006年度に履修登録・成績入力システムとして「全学日本語コースWebシステム」を開発した。本システムは日本語コースを取り巻く環境の変化に合わせ，修正や新たな機能の追加を繰り返しながら現在まで運用を行っている。本稿では，2013年度以降に行った改訂に重点を置きながら，全額日本語コースWebシステムの機能を紹介する。今後，さらなるシステムの見直しが求められており，本稿は新システム構築のための資料としての意義を持つ。 en-copyright= kn-copyright= en-aut-name=Yukako en-aut-sei= en-aut-mei=Yukako kn-aut-name=内丸裕佳子 kn-aut-sei=内丸 kn-aut-mei=裕佳子 aut-affil-num=1 ORCID= en-aut-name=BANNOEri en-aut-sei=BANNO en-aut-mei=Eri kn-aut-name=坂野永理 kn-aut-sei=坂野 kn-aut-mei=永理 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil= affil-num=2 en-affil= kn-affil= en-keyword=日本語コースWebシステム kn-keyword=日本語コースWebシステム en-keyword=システム改訂 kn-keyword=システム改訂 en-keyword=カリキュラム変更 kn-keyword=カリキュラム変更 en-keyword=4学期制導入 kn-keyword=4学期制導入 END start-ver=1.4 cd-journal=joma no-vol=23 cd-vols= no-issue=2 article-no= start-page=e25232 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210218 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Impact of the COVID-19 Pandemic on the Psychological Distress of Medical Students in Japan: Cross-sectional Survey Study en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background:
The COVID-19 pandemic has negatively affected medical education. However, little data are available about medical students’ distress during the pandemic.
Objective:
This study aimed to provide details on how medical students have been affected by the pandemic.
Methods:
A cross-sectional study was conducted. A total of 717 medical students participated in the web-based survey. The survey included questions about how the participants’ mental status had changed from before to after the Japanese nationwide state of emergency (SOE).
Results:
Out of 717 medical students, 473 (66.0%) participated in the study. In total, 29.8% (141/473) of the students reported concerns about the shift toward online education, mostly because they thought online education would be ineffective compared with in-person learning. The participants’ subjective mental health status significantly worsened after the SOE was lifted (P<.001). Those who had concerns about a shift toward online education had higher odds of having generalized anxiety and being depressed (odds ratio [OR] 1.97, 95% CI 1.19-3.28) as did those who said they would request food aid (OR 1.99, 95% CI 1.16-3.44) and mental health care resources (OR 3.56, 95% CI 2.07-6.15).
Conclusions:
Given our findings, the sudden shift to online education might have overwhelmed medical students. Thus, we recommend that educators inform learners that online learning is not inferior to in-person learning, which could attenuate potential depression and anxiety. en-copyright= kn-copyright= en-aut-name=NishimuraYoshito en-aut-sei=Nishimura en-aut-mei=Yoshito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OchiKanako en-aut-sei=Ochi en-aut-mei=Kanako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TokumasuKazuki en-aut-sei=Tokumasu en-aut-mei=Kazuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ObikaMikako en-aut-sei=Obika en-aut-mei=Mikako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HagiyaHideharu en-aut-sei=Hagiya en-aut-mei=Hideharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KataokaHitomi en-aut-sei=Kataoka en-aut-mei=Hitomi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Department of General Medicine, Okayama University Hospital kn-affil= affil-num=2 en-affil=Department of General Medicine, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of General Medicine, Okayama University Hospital kn-affil= affil-num=4 en-affil=Department of General Medicine, Okayama University Hospital kn-affil= affil-num=5 en-affil=Department of General Medicine, Okayama University Hospital kn-affil= affil-num=6 en-affil=Department of General Medicine, Okayama University Hospital kn-affil= affil-num=7 en-affil=Department of General Medicine, Okayama University Hospital kn-affil= en-keyword=COVID-19 kn-keyword=COVID-19 en-keyword=online education kn-keyword=online education en-keyword=depression kn-keyword=depression en-keyword=pandemic kn-keyword=pandemic en-keyword=anxiety kn-keyword=anxiety en-keyword=medical student kn-keyword=medical student END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=1 article-no= start-page=39 end-page=44 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=202102 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Influence of and Risk Factors for Axillary Web Syndrome Following Surgery for Breast Cancer en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this study, we examined whether axillary web syndrome (AWS) in patients with breast cancer following axil-lary lymph node dissection affects range of motion (ROM), upper extremity function, and quality of life (QOL). The risk factors for AWS were also evaluated in a total of 238 consecutive breast cancer patients follow-ing axillary lymph node dissection. At 1, 2, and 3 months after surgery, there were no significant differences between the AWS group and the non-AWS group in upper-limb function or QOL. At 2 months after surgery, shoulder flexion and abduction ROM were significantly higher in the AWS group than in the non-AWS group (p < 0.05). Self-training time at home was not significantly different between the groups at 1, 2, or 3 months. Only age was a significant predictor of AWS at 1 month after surgery (p < 0.05). The AWS group in the present study did not have worse results for shoulder joint ROM, upper-limb function, and QOL than the non-AWS group. Younger age should be useful for predicting the development of AWS in the early postoperative period. en-copyright= kn-copyright= en-aut-name=AkezakiYoshiteru en-aut-sei=Akezaki en-aut-mei=Yoshiteru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NakataEiji en-aut-sei=Nakata en-aut-mei=Eiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KikuuchiMasato en-aut-sei=Kikuuchi en-aut-mei=Masato kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TominagaRitsuko en-aut-sei=Tominaga en-aut-mei=Ritsuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KurokawaHideaki en-aut-sei=Kurokawa en-aut-mei=Hideaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HamadaMakiko en-aut-sei=Hamada en-aut-mei=Makiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AogiKenjiro en-aut-sei=Aogi en-aut-mei=Kenjiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=OhsumiShozo en-aut-sei=Ohsumi en-aut-mei=Shozo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=SugiharaShinsuke en-aut-sei=Sugihara en-aut-mei=Shinsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil=Division of Physical Therapy, Kochi Professional University of Rehabilitation kn-affil= affil-num=2 en-affil=Department of Orthopaedic Surgery, Okayama University Hospital kn-affil= affil-num=3 en-affil=Department of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center kn-affil= affil-num=4 en-affil=Department of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center kn-affil= affil-num=5 en-affil=Department of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center kn-affil= affil-num=6 en-affil=Department of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center kn-affil= affil-num=7 en-affil=Breast Oncology, National Hospital Organization Shikoku Cancer Center kn-affil= affil-num=8 en-affil=Breast Oncology, National Hospital Organization Shikoku Cancer Center kn-affil= affil-num=9 en-affil=Department of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center kn-affil= en-keyword=breast cancer kn-keyword=breast cancer en-keyword=axillary web syndrome kn-keyword=axillary web syndrome en-keyword=age kn-keyword=age en-keyword=upper limb function kn-keyword=upper limb function en-keyword=quality of life kn-keyword=quality of life END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue= article-no= start-page=833 end-page=847 dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210119 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Web access monitoring mechanism via Android WebView for threat analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Many Android apps employ WebView, a component that enables the display of web content in the apps without redirecting users to web browser apps. However, WebView might also be used for cyberattacks. Moreover, to the best of our knowledge, although some countermeasures based on access control have been reported for attacks exploiting WebView, no mechanism for monitoring web access via WebView has been proposed and no analysis results focusing on web access via WebView are available. In consideration of this limitation, we propose a web access monitoring mechanism for Android WebView to analyze web access via WebView and clarify attacks exploiting WebView. In this paper, we present the design and implementation of this mechanism by modifying Chromium WebView without any modifications to the Android framework or Linux kernel. The evaluation results of the performance achieved on introducing the proposed mechanism are also presented here. Moreover, the result of threat analysis of displaying a fake virus alert while browsing websites on Android is discussed to demonstrate the effectiveness of the proposed mechanism. en-copyright= kn-copyright= en-aut-name=ImamuraYuta en-aut-sei=Imamura en-aut-mei=Yuta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OritoRintaro en-aut-sei=Orito en-aut-mei=Rintaro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=UekawaHiroyuki en-aut-sei=Uekawa en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ChaikaewKritsana en-aut-sei=Chaikaew en-aut-mei=Kritsana kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=LeelaprutePattara en-aut-sei=Leelaprute en-aut-mei=Pattara kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SatoMasaya en-aut-sei=Sato en-aut-mei=Masaya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=3 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=4 en-affil=Faculty of Engineering, Kasetsart University kn-affil= affil-num=5 en-affil=Faculty of Engineering, Kasetsart University kn-affil= affil-num=6 en-affil=Graduate School of Natural Science and Technology kn-affil= affil-num=7 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= en-keyword=Android kn-keyword=Android en-keyword=WebView kn-keyword=WebView en-keyword=Web access monitoring kn-keyword=Web access monitoring en-keyword=Web security kn-keyword=Web security en-keyword=Threat analysis kn-keyword=Threat analysis en-keyword=Fake virus alert kn-keyword=Fake virus alert END start-ver=1.4 cd-journal=joma no-vol=E98D cd-vols= no-issue=4 article-no= start-page=807 end-page=811 dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=2015 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Access Control to Prevent Malicious JavaScript Code Exploiting Vulnerabilities of WebView in Android OS en-subtitle= kn-subtitle= en-abstract= kn-abstract=Android applications that using WebView can load and display web pages. Interaction with web pages allows JavaScript code within the web pages to access resources on the Android device by using the Java object, which is registered into WebView. If this WebView feature were exploited by an attacker, JavaScript code could be used to launch attacks, such as stealing from or tampering personal information in the device. To address these threats, we propose an access control on the security-sensitive APIs at the Java object level. The proposed access control uses static analysis to identify these security-sensitive APIs, detects threats at runtime, and notifies the user if threats are detected, thereby preventing attacks from web pages. en-copyright= kn-copyright= en-aut-name=YuJing en-aut-sei=Yu en-aut-mei=Jing kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= en-keyword=Android kn-keyword=Android en-keyword=WebView kn-keyword=WebView en-keyword=static analysis kn-keyword=static analysis en-keyword=access control kn-keyword=access control END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=1628 end-page=1633 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=2013 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Access Control to Prevent Attacks Exploiting Vulnerabilities of WebView in Android OS en-subtitle= kn-subtitle= en-abstract= kn-abstract=Android applications that using WebView can load and display web pages. Furthermore, by using the APIs provided in WebView, Android applications can interact with web pages. The interaction allows JavaScript code within the web pages to access resources on the Android device by using the Java object, which is registered into WebView. If this WebView feature were exploited by an attacker, JavaScript code could be used to launch attacks, such as stealing from or tampering personal information in the device. To address these threats, we propose a method that performs access control on the security-sensitive APIs at the Java object level. The proposed method uses static analysis to identify these security-sensitive APIs, detects threats at runtime, and notifies the user if threats are detected, thereby preventing attacks from web pages. en-copyright= kn-copyright= en-aut-name=YuJing en-aut-sei=Yu en-aut-mei=Jing kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YamauchiToshihiro en-aut-sei=Yamauchi en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= en-keyword=Java kn-keyword=Java en-keyword=Androids kn-keyword=Androids en-keyword=Humanoid robots kn-keyword=Humanoid robots en-keyword=Web pages kn-keyword=Web pages en-keyword=Smart phones kn-keyword=Smart phones en-keyword=Assembly kn-keyword=Assembly en-keyword=Browsers kn-keyword=Browsers END start-ver=1.4 cd-journal=joma no-vol=16 cd-vols= no-issue=2 article-no= start-page=137 end-page=149 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20191023 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A proposal of calligraphy learning assistant system with letter portion practice function using projection mapping en-subtitle= kn-subtitle= en-abstract= kn-abstract=Purpose
For several decades, calligraphy has been popular among people in Japan, China, and even in the world. Traditionally, a teacher teaches how to write letters on a paper with a brush, and a student will imitate them by referring to the model letters. However, if a teacher is not available, this method will not be applicable either. This study aims to propose a calligraphy learning assistant system (CLAS) using projection mapping, which allows a student to learn calligraphy by him/herself.
Design/methodology/approach
By following the letter writing video of a teacher that is directly projected on the paper, a student is able to learn the stroke order and writing speed in addition to the letter shape. Moreover, the letter portion practice function is incorporated in CLAS to allow a learner to repeat practicing hard portions of each letter.
Findings
For evaluations, the authors implemented CLAS using Raspberry Pi and open-source software and asked students to use it. The results confirmed that CLAS is effective in improving calligraphy skills of novice students.
Originality/value
With CLAS, a student can practice calligraphy using a conventional brush, ink and paper at a desk while looking at the model letter writing of a teacher projected on the paper using projection mapping. en-copyright= kn-copyright= en-aut-name=HudaSamsul en-aut-sei=Huda en-aut-mei=Samsul kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KuribayashiMinoru en-aut-sei=Kuribayashi en-aut-mei=Minoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KaoWen-Chung en-aut-sei=Kao en-aut-mei=Wen-Chung kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=2 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=3 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=4 en-affil=Department of Electrical Engineering, National Taiwan Normal University kn-affil= en-keyword=Raspberry Pi kn-keyword=Raspberry Pi en-keyword=Calligraphy kn-keyword=Calligraphy en-keyword=Learning assistant system kn-keyword=Learning assistant system en-keyword=Projection mapping kn-keyword=Projection mapping END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=6 article-no= start-page=830 end-page=846 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=202006 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Icodextrin Versus Glucose Solutions for the Once-Daily Long Dwell in Peritoneal Dialysis: An Enriched Systematic Review and Meta-analysis of Randomized Controlled Trials en-subtitle= kn-subtitle= en-abstract= kn-abstract=Rationale & Objective
The efficacy and safety of icodextrin versus glucose-only peritoneal dialysis (PD) regimens is unclear. The aim of this study was to compare once-daily long-dwell icodextrin versus glucose among patients with kidney failure undergoing PD.
Study Design
Systematic review of randomized controlled trials (RCTs), enriched with unpublished data from investigator-initiated and industry-sponsored studies.
Setting & Study Populations
Individuals with kidney failure receiving regular PD treatment enrolled in clinical trials of dialysate composition.
Selection Criteria for Studies
Medline, Embase, CENTRAL, Ichushi Web, 10 Chinese databases, clinical trials registries, conference proceedings, and citation lists from inception to November 2018. Further data were obtained from principal investigators and industry clinical study reports.
Data Extraction
2 independent reviewers selected studies and extracted data using a prespecified extraction instrument.
Analytic Approach
Qualitative synthesis of demographics, measurement scales, and outcomes. Quantitative synthesis with Mantel-Haenszel risk ratios (RRs), Peto odds ratios (ORs), or (standardized) mean differences (MDs). Risk of bias of included studies at the outcome level was assessed using the Cochrane risk-of-bias tool for RCTs.
Results
19 RCTs that enrolled 1,693 participants were meta-analyzed. Ultrafiltration was improved with icodextrin (medium-term MD, 208.92 [95% CI, 99.69-318.14] mL/24 h; high certainty of evidence), reflected also by fewer episodes of fluid overload (RR, 0.43 [95% CI, 0.24-0.78]; high certainty). Icodextrin-containing PD probably decreased mortality risk compared to glucose-only PD (Peto OR, 0.49 [95% CI, 0.24-1.00]; moderate certainty). Despite evidence of lower peritoneal glucose absorption with icodextrin-containing PD (medium-term MD, ?40.84 [95% CI, ?48.09 to ?33.59] g/long dwell; high certainty), this did not directly translate to changes in fasting plasma glucose (?0.50 [95% CI, ?1.19 to 0.18] mmol/L; low certainty) and hemoglobin A1c levels (?0.14% [95% CI, ?0.34% to 0.05%]; high certainty). Safety outcomes and residual kidney function were similar in both groups; health-related quality-of-life and pain scores were inconclusive.
Limitations
Trial quality was variable. The follow-up period was heterogeneous, with a paucity of assessments over the long term. Mortality results are based on just 32 events and were not corroborated using time-to-event analysis of individual patient data.
Conclusions
Icodextrin for once-daily long-dwell PD has clinical benefit for some patients, including those not meeting ultrafiltration targets and at risk for fluid overload. Future research into patient-centered outcomes and cost-effectiveness associated with icodextrin is needed. en-copyright= kn-copyright= en-aut-name=GoossenK?the en-aut-sei=Goossen en-aut-mei=K?the kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=BeckerMonika en-aut-sei=Becker en-aut-mei=Monika kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MarshallMark R. en-aut-sei=Marshall en-aut-mei=Mark R. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=B?hnStefanie en-aut-sei=B?hn en-aut-mei=Stefanie kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=BreuingJessica en-aut-sei=Breuing en-aut-mei=Jessica kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=FiranekCatherine A. en-aut-sei=Firanek en-aut-mei=Catherine A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=HessSimone en-aut-sei=Hess en-aut-mei=Simone kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NariaiHisanori en-aut-sei=Nariai en-aut-mei=Hisanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=SloandJames A. en-aut-sei=Sloand en-aut-mei=James A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=YaoQiang en-aut-sei=Yao en-aut-mei=Qiang kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=ChangTae Ik en-aut-sei=Chang en-aut-mei=Tae Ik kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=ChenJinBor en-aut-sei=Chen en-aut-mei=JinBor kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=PaniaguaRam?n en-aut-sei=Paniagua en-aut-mei=Ram?n kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=TakatoriYuji en-aut-sei=Takatori en-aut-mei=Yuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=WadaJun en-aut-sei=Wada en-aut-mei=Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=PieperDawid en-aut-sei=Pieper en-aut-mei=Dawid kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= affil-num=1 en-affil=Institute for Research in Operative Medicine, Faculty of Health, Department of Medicine, Witten/Herdecke University kn-affil= affil-num=2 en-affil=Institute for Research in Operative Medicine, Faculty of Health, Department of Medicine, Witten/Herdecke University kn-affil= affil-num=3 en-affil=Baxter Healthcare (Asia) Pte Ltd kn-affil= affil-num=4 en-affil=Institute for Research in Operative Medicine, Faculty of Health, Department of Medicine, Witten/Herdecke University kn-affil= affil-num=5 en-affil=Institute for Research in Operative Medicine, Faculty of Health, Department of Medicine, Witten/Herdecke University kn-affil= affil-num=6 en-affil=Baxter Healthcare International kn-affil= affil-num=7 en-affil=nstitute for Research in Operative Medicine, Faculty of Health, Department of Medicine, Witten/Herdecke University kn-affil= affil-num=8 en-affil=Baxter Japan Ltd kn-affil= affil-num=9 en-affil=Baxter Healthcare International kn-affil= affil-num=10 en-affil=Baxter (China) Investment Co. Ltd kn-affil= affil-num=11 en-affil=Department of Internal Medicine, NHIS Medical Center kn-affil= affil-num=12 en-affil=Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine kn-affil= affil-num=13 en-affil=Research Unit, Unidad de Investigaci?n M?dica en Enfermedades Nefrol?gicas, Centro M?dico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS) kn-affil= affil-num=14 en-affil=Internal Medicine, Rijinkai Medical Foundation, Socio-Medical Corporation, Kohsei General Hospital kn-affil= affil-num=15 en-affil=Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=16 en-affil=nstitute for Research in Operative Medicine, Faculty of Health, Department of Medicine, Witten/Herdecke University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=16 cd-vols= no-issue=1 article-no= start-page=115 end-page=135 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20191003 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A proposal of Android Programming Learning Assistant System with implementation of basic application learning en-subtitle= kn-subtitle= en-abstract= kn-abstract=Purpose
With rapid increase of Android devices and application systems, there is a strong demand for Android application programmers. A lot of schools are offering Android programming courses to meet this demand. However, Android programming can be different from the conventional one because it needs interactive functions through interfaces with users, which makes the study more difficult. This paper aims to propose an Android Programming Learning Assistance System, namely, APLAS, to assist the Java-based Android programming study and education.
Design/methodology/approach
By adopting the test-driven development method, APLAS is designed to achieve independent learning without the presence of teachers. Using JUnit and Robolectric, the answers from the students are automatically marked in APLAS. To cover extensive materials in Android programming, APLAS offers four stages where each stage involves several topics.
Findings
To evaluate the effectiveness of APLAS, we implemented the Unit Converter assignment that covers the first two topics, namely, Basic user interface in the first stage and basic activity in the second stage. Through solving the assignment, it is expected to learn basic application development. Forty novice students of an IT department in Indonesia were asked to solve both topics separately.
Originality/value
The results show that APLAS is useful and helpful for the self-study of Android programming, as they could complete codes with good execution performances. en-copyright= kn-copyright= en-aut-name=SyaifudinYan Watequlis en-aut-sei=Syaifudin en-aut-mei=Yan Watequlis kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KuribayashiMinoru en-aut-sei=Kuribayashi en-aut-mei=Minoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KaoWen-Chung en-aut-sei=Kao en-aut-mei=Wen-Chung kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=2 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=3 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=4 en-affil=National Taiwan Normal University kn-affil= en-keyword=Android application kn-keyword=Android application en-keyword=APLAS kn-keyword=APLAS en-keyword=JUnit kn-keyword=JUnit en-keyword=Learning system kn-keyword=Learning system en-keyword= Learning system kn-keyword= Learning system en-keyword=Test-driven development method kn-keyword=Test-driven development method en-keyword=Index terms APLAS kn-keyword=Index terms APLAS en-keyword=Java kn-keyword=Java END start-ver=1.4 cd-journal=joma no-vol=19 cd-vols= no-issue=1 article-no= start-page=211 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20191209 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Prognostic significance of the controlling nutritional status (CONUT) score in patients undergoing hepatectomy for hepatocellular carcinoma: a systematic review and meta-analysis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: The clinical value of the controlling nutritional status (CONUT) score in hepatocellular carcinoma (HCC) has increased. The aim of this meta-analysis was to systematically review the association between the CONUT score and outcomes in patients undergoing hepatectomy for HCC.
Methods: Embase, Medline Ovid, Web of Science, Cochrane CENTRAL, and Google Scholar were systematically searched. Random effects meta-analyses were conducted to examine the prognostic value of the CONUT score in HCC patients.
Results: A total of five studies including 4679 patients were found to be eligible and analyzed in the meta-analysis. The CONUT score was significantly associated with overall survival (HR 1.78, 95%CI = 1.20-2.64, P = 0.004, I-2 = 79%), recurrence-free survival (HR 1.34, 95%CI = 1.17-1.53, P < 0.001, I-2 = 16%) and postoperative major complications (OR 1.85, 95%CI: 1.19-2.87, P = 0.006, I-2 = 72%) in HCC patients. Moreover, the CONUT score was associated with the Child-Pugh classification, liver cirrhosis, ICGR15, and tumor differentiation. However, it was not associated with tumor size, tumor number, and microvascular invasion.
Conclusions: The CONUT score is an independent prognostic indicator of the prognosis and is associated with postoperative major complications and hepatic functional reserve in HCC patients. en-copyright= kn-copyright= en-aut-name=TakagiKosei en-aut-sei=Takagi en-aut-mei=Kosei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=DomagalaPiotr en-aut-sei=Domagala en-aut-mei=Piotr kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=PolakWojciech G. en-aut-sei=Polak en-aut-mei=Wojciech G. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=BuettnerStefan en-aut-sei=Buettner en-aut-mei=Stefan kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=IjzermansJan N. M. en-aut-sei=Ijzermans en-aut-mei=Jan N. M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil=Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences kn-affil= affil-num=2 en-affil=Department of Surgery, Erasmus MC, University Medical Center Rotterdam kn-affil= affil-num=3 en-affil=Department of Surgery, Erasmus MC, University Medical Center Rotterdam kn-affil= affil-num=4 en-affil=Department of Surgery, Erasmus MC, University Medical Center Rotterdam kn-affil= affil-num=5 en-affil=Department of Surgery, Erasmus MC, University Medical Center Rotterdam kn-affil= en-keyword=Controlling nutritional status (CONUT) score kn-keyword=Controlling nutritional status (CONUT) score en-keyword=Hepatocellular carcinoma kn-keyword=Hepatocellular carcinoma en-keyword=Outcome kn-keyword=Outcome en-keyword=Meta-analysis kn-keyword=Meta-analysis END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=855 end-page=864 dt-received= dt-revised= dt-accepted= dt-pub-year=2018 dt-pub=20180719 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A Proposal of Code Completion Problem for Java Programming Learning Assistant System en-subtitle= kn-subtitle= en-abstract= kn-abstract= To enhance Java programming educations in schools, we have developed a Web-based Java Programming Learning Assistant System (JPLAS) that provides a variety of programming assignments to cover different learning stages. For the first stage, JPLAS offers the element fill-in-blank problem where students study the grammar and code reading through filling the blank elements, composed of reserved words, identifiers, and control symbols, in a high-quality code. Unfortunately, it has been observed that students can fill the blanks without reading the code carefully, because the choice is limited for each blank. In this paper, we propose a code completion problem as a generalization of the element fill-in-blank problem. To solve the drawback, it does not explicitly show blank locations in the code, which expects students to carefully read the code to understand the grammar and code structure. The correctness of the answer is verified through string matching of each statement with the filled elements and the corresponding correct one. Besides, to encourage students to study readable code writing, the correct statement satisfies the coding rules including the spaces. For evaluations, we generated six code completion and element fill-in-blank problems respectively, and asked ten students in two universities to solve them. Their solution results show that the code completion problem is much harder than the element fill-in-blank problem, and requires far deeper code reading and understanding of coding rules. en-copyright= kn-copyright= en-aut-name=Htoo Htoo Sandi Kyaw en-aut-sei=Htoo Htoo Sandi Kyaw en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=Shwe Thinzar Aung en-aut-sei=Shwe Thinzar Aung en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=Hnin Aye Thant en-aut-sei=Hnin Aye Thant en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Information Science and TechnologyUniversity of Technology Yatanarpon Cyber City kn-affil= affil-num=2 en-affil=Department of Information Science and TechnologyUniversity of Technology Yatanarpon Cyber City kn-affil= affil-num=3 en-affil=Department of Electrical and Communication Engineering Okayama University kn-affil= affil-num=4 en-affil=Department of Electrical and Communication Engineering Okayama University kn-affil= END start-ver=1.4 cd-journal=joma no-vol=5 cd-vols= no-issue=5 article-no= start-page=722 end-page=734 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190713 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Current Disease Management of Primary Urethral Carcinoma en-subtitle= kn-subtitle= en-abstract= kn-abstract=Context: Primary urethral cancer (PUC) is a rare cancer entity. Owing to the low incidence of this malignancy, the main body of literature consists mainly of case reports, making evidence-based management recommendations difficult.
Objective: To review reported disease management strategies of PUC and their impact on oncological outcomes.
Evidence acquisition: A systematic research was performed according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement using Medline, Scopus, and Web of Science, to find studies of the past 10yr including ?20 patients, and investigating treatment strategies and their impact on outcomes of the three most frequent histologies: urothelial carcinoma, adenocarcinoma, and squamous cell carcinoma. Evidence synthesis: In localized PUC, penis-sparing surgery can be performed in males, while in females, complete urethrectomy with surrounding tissue is advised to minimize recurrence due to positive margins. Radiotherapy (RT) has worse survival and recurrence rates, as well as more adverse effects, than surgery, limiting its use in genital-preserving therapy. Locally advanced PUC should be treated with multimodal therapy, as monotherapies result in inferior recurrence and survival rates. Extent of surgery is still undecided, favoring radical cyst(oprostat)ectomy with total urethrectomy (RCU). Lymph node involvement is a predictor of survival, highlighting the role of lymph node dissection for disease control and staging. RT can improve survival in combination with surgery and/or chemotherapy (CHT). Neoadjuvant platinum-based CHT can improve overall and recurrence-free survival. At recurrence, salvage therapy with surgery and/or CHT can improve survival. Superficial urothelial carcinoma of the prostatic urethra can be treated with transurethral resection. Stromal invasion often features concomitant bladder cancer with a poor prognosis and requires RCU with or without systemic preoperative CHT.
Conclusions: PUC is a rare malignancy with an often poor natural course, requiring a stage- and gender-specific risk-based treatment strategy. The role of systematic perioperative CHT and the extent of surgery are becoming more important.
Patient summary: In this review, we looked at the treatment options for primary urethral cancer. We found that while an organ-confined disease can be managed with local resection, growth beyond the organ border makes a combination of different treatment modalities, such as surgery and systematic chemotherapy, necessary to improve outcomes. en-copyright= kn-copyright= en-aut-name=JanischFlorian en-aut-sei=Janisch en-aut-mei=Florian kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AbufarajMohammad en-aut-sei=Abufaraj en-aut-mei=Mohammad kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FajkovicHarun en-aut-sei=Fajkovic en-aut-mei=Harun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KimuraShoji en-aut-sei=Kimura en-aut-mei=Shoji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=IwataTakehiro en-aut-sei=Iwata en-aut-mei=Takehiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NyiradyPeter en-aut-sei=Nyirady en-aut-mei=Peter kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=RinkMichael en-aut-sei=Rink en-aut-mei=Michael kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=ShariatShahrokh F. en-aut-sei=Shariat en-aut-mei=Shahrokh F. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil=Department of Urology, Medical University of Vienna kn-affil= affil-num=2 en-affil=Department of Urology, Medical University of Vienna kn-affil= affil-num=3 en-affil=Department of Urology, Medical University of Vienna kn-affil= affil-num=4 en-affil=Department of Urology, Medical University of Vienna kn-affil= affil-num=5 en-affil=Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil= affil-num=6 en-affil=Department of Urology, Semmelweis University kn-affil= affil-num=7 en-affil=Department of Urology, University Medical Center Hamburg-Eppendorf kn-affil= affil-num=8 en-affil=Department of Urology, Medical University of Vienna kn-affil= en-keyword=Disease management kn-keyword=Disease management en-keyword=Primary urethral carcinoma kn-keyword=Primary urethral carcinoma en-keyword=Prognosis kn-keyword=Prognosis en-keyword=Therapy kn-keyword=Therapy en-keyword=Treatment kn-keyword=Treatment END start-ver=1.4 cd-journal=joma no-vol=9 cd-vols= no-issue= article-no= start-page=1 end-page=12 dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190320 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Google classroom and Chromebook as an Educational IT system kn-title=教育ITシステムとしてのGoogle classroomとChromebook en-subtitle= kn-subtitle= en-abstract= kn-abstract=　「2030年代を生きる力」と「働き方改革に利するITスキル」を教育するためのアクティブ・ラーニングをサポートする教育ITシステムの構築においてGoogle classroomとChromebookを検討した。教育クラウドプラットフォームのひとつであるClassroomと，Webアプリケーションを利用するChromebookを用いて教育ITシステムを構築すると低コストで導入と運用ができると考えられた。またこの教育ITシステムはGoogleアカウントを経由して作業環境やデータ・ファイルをスマートフォンとPCの間で同期するため，スマホ・ネイティブ世代の情報処理能力をスムースに拡張することができる。これにより国際化が要請されているスマホ・ネイティブ世代が経験するデジタル・デバイドを軽減し，また2030年代に向けて我が国のビジネス・ワーカーが持つITスキルを向上させることが期待される。 en-copyright= kn-copyright= en-aut-name=Yamakawa?un?i en-aut-sei=Yamakawa en-aut-mei=?un?i kn-aut-name=山川純次 kn-aut-sei=山川 kn-aut-mei=純次 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 en-keyword=アクティブ・ラーニング kn-keyword=アクティブ・ラーニング en-keyword=教育ITシステム kn-keyword=教育ITシステム en-keyword=Google classroom kn-keyword=Google classroom en-keyword=Chromebook kn-keyword=Chromebook en-keyword=スマホ・ ネイティブ世代 kn-keyword=スマホ・ ネイティブ世代 END start-ver=1.4 cd-journal=joma no-vol=79 cd-vols= no-issue= article-no= start-page=607 end-page=608 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=201703 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=HTML内の並列構造を利用したWebページ上のイベント情報抽出 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=河村一希 kn-aut-sei=河村 kn-aut-mei=一希 aut-affil-num=1 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue=3 article-no= start-page=145 end-page=154 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20171229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A design-aware test code approach for code writing problem in Java programming learning assistant system en-subtitle= kn-subtitle= en-abstract= kn-abstract= To advance Java programming educations, we have developed the web-based Java programming learning assistant system (JPLAS) that provides the code writing problem. This problem asks a student to write a source code for a given assignment, where the correctness is verified by running the test code on JUnit. In this paper, we propose a design-aware test code approach for the code writing problem. The design-aware test code tests any important method in the model source code that has the advisable design for the assignment. Thus, by writing a code that can pass it, a student is expected to implement the code with the proper classes/methods in the model code. In evaluations of the proposal, all the students could complete highly qualitative codes for five graph algorithms using the design-aware test codes, where the code quality metrics were measured by metrics plugin for Eclipse. en-copyright= kn-copyright= en-aut-name=Khin Khin Zaw en-aut-sei=Khin Khin Zaw en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= affil-num=2 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil= en-keyword=Java programming learning assistant system kn-keyword=Java programming learning assistant system en-keyword=JPLAS kn-keyword=JPLAS en-keyword=design-aware test code kn-keyword=design-aware test code en-keyword=JUnit kn-keyword=JUnit en-keyword=metric plugin kn-keyword=metric plugin en-keyword=breadth-first-search kn-keyword=breadth-first-search en-keyword=BFS kn-keyword=BFS END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue=1 article-no= start-page=116 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170727 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A software architecture for Java programming learning assistant system en-subtitle= kn-subtitle= en-abstract= kn-abstract= For advancements of Java programming educations, we have developed a Web-based Java Programming Learning System (JPLAS). JPLAS provides four problems with different levels, namely, element fill-inblank problem, value trace problem, statement fill-in-blank problem, and code writing problem, to cover students at different learning stages. Unfortunately, since JPLAS has been implemented by a number of students who studied in our group at different years, the code has become complex and redundant, which makes further extensions of JPLAS extremely hard. In this paper, we propose a software architecture for JPLAS to avoid redundancy. Based on the MVC model, our proposal uses Java for the model (M), HTML/CSS/JavaScript for the view (V), and JSP for the controller (C). Besides, adopting a design pattern, the marking functions of the four problems are implemented uniformly. For evaluations, after JPLAS is implemented with this architecture, the number of code files is compared with that of the previous implementation, and the number of additional files is examined for two new functions. en-copyright= kn-copyright= en-aut-name=IshiharaNobuya en-aut-sei=Ishihara en-aut-mei=Nobuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FunabikiNobuo en-aut-sei=Funabiki en-aut-mei=Nobuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KuribayashiMinoru en-aut-sei=Kuribayashi en-aut-mei=Minoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KaoWen-Chung en-aut-sei=Kao en-aut-mei=Wen-Chung kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=2 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=3 en-affil=Department of Electrical and Communication Engineering, Okayama University kn-affil= affil-num=4 en-affil=Department of Electrical Engineering, National Taiwan Normal University kn-affil= en-keyword=JPLAS kn-keyword=JPLAS en-keyword=Java programming education kn-keyword=Java programming education en-keyword=Web application kn-keyword=Web application en-keyword= MVC model kn-keyword= MVC model en-keyword=Software architecture kn-keyword=Software architecture END start-ver=1.4 cd-journal=joma no-vol=166 cd-vols= no-issue= article-no= start-page=117 end-page=126 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20171128 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on ?Active Learning? in the Subjects on the Significance of the Teaching Profession : through Analysis of Syllabuses of National Teacher Training Universities and Faculties kn-title=教職論における「アクティブ・ラーニング」に関する研究 : 国立教員養成系大学・学部のシラバスの分析を通して en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本論文は，教員免許状の取得に必要な「教職の意義等に関する科目（以下，本論文では「教職論」とする。）」において「アクティブ・ラーニング」がどのような形態で，どのような内容で取り組まれているのかを明らかにすることを目的としている。研究対象を44 の国立教員養成系大学・学部で開設されている教職論とし，WEBに公開されているシラバスを分析することとした。その結果，「アクティブ・ラーニング」を導入している大学は33 校（75.0％）であった。主な実施形態としては「グループワーク」「フィールドワーク・省察」「プレゼンテーション・発表」「討論・ディベート」であった。主な内容としては「附属学校園等訪問とその省察」「学校教員の講演会・座談会」「自身の教育体験の省察・交流」「目指す教師像の探究」「現代の教育課題の検討」「模擬授業・場面指導」等であった。 en-copyright= kn-copyright= en-aut-name=ImaiYasuyoshi en-aut-sei=Imai en-aut-mei=Yasuyoshi kn-aut-name=今井康好 kn-aut-sei=今井 kn-aut-mei=康好 aut-affil-num=1 ORCID= en-aut-name=MoriyasuFumihiko en-aut-sei=Moriyasu en-aut-mei=Fumihiko kn-aut-name=森安史彦 kn-aut-sei=森安 kn-aut-mei=史彦 aut-affil-num=2 ORCID= en-aut-name=MuramatsuAtsushi en-aut-sei=Muramatsu en-aut-mei=Atsushi kn-aut-name=村松敦 kn-aut-sei=村松 kn-aut-mei=敦 aut-affil-num=3 ORCID= en-aut-name=IwadouHideaki en-aut-sei=Iwadou en-aut-mei=Hideaki kn-aut-name=岩堂秀明 kn-aut-sei=岩堂 kn-aut-mei=秀明 aut-affil-num=4 ORCID= en-aut-name=SuminoYoshihisa en-aut-sei=Sumino en-aut-mei=Yoshihisa kn-aut-name=住野好久 kn-aut-sei=住野 kn-aut-mei=好久 aut-affil-num=5 ORCID= affil-num=1 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学大学院教育学研究科 affil-num=2 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学大学院教育学研究科 affil-num=3 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学大学院教育学研究科 affil-num=4 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学大学院教育学研究科 affil-num=5 en-affil=Graduate School of Education, Okayama University kn-affil=岡山大学大学院教育学研究科 en-keyword=教職の意義等に関する科目 kn-keyword=教職の意義等に関する科目 en-keyword=アクティブ・ラーニング kn-keyword=アクティブ・ラーニング en-keyword=シラバス kn-keyword=シラバス END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue= article-no= start-page=135 end-page=150 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=201412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Development of "Shoshin Nembtsuge" e-Learning material kn-title=浄土真宗各派「正信念仏偈」のe-ラーニング教材 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　浄土真宗各派の日常的な勤行において用いられる「正信偈」の旋律を収集・採譜し、web 上にデータ ベース化した。採譜にあたっては、主に西洋音楽で広く用いられ、最も一般的な記譜法である五線譜を 用い、初学者が容易に理解できるような記譜を工夫するとともに、口伝によって伝承されてきた旋律を、 可能な限り忠実に再現できるように配慮した。その結果、これまでほとんど知られてこなかった各派「正信 偈」の旋律を、広く一般に共有することが可能となり、将来的には、「正信偈」に関心をもつ学習者がe- ラーニングの教材として利用できるようになった。 en-copyright= kn-copyright= en-aut-name=ToyamaKazuhiro en-aut-sei=Toyama en-aut-mei=Kazuhiro kn-aut-name=遠山和大 kn-aut-sei=遠山 kn-aut-mei=和大 aut-affil-num=1 ORCID= en-aut-name=FukamiYukiko en-aut-sei=Fukami en-aut-mei=Yukiko kn-aut-name=深見友紀子 kn-aut-sei=深見 kn-aut-mei=友紀子 aut-affil-num=2 ORCID= en-aut-name=AkahaneMiki en-aut-sei=Akahane en-aut-mei=Miki kn-aut-name=赤羽美希 kn-aut-sei=赤羽 kn-aut-mei=美希 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学教育開発センター affil-num=2 en-affil= kn-affil=京都女子大学 発達教育学部 affil-num=3 en-affil= kn-affil=東京音楽大学 音楽教育専攻 en-keyword=浄土真宗 kn-keyword=浄土真宗 en-keyword=仏教声明 kn-keyword=仏教声明 en-keyword=正信偈 kn-keyword=正信偈 en-keyword=e-ラーニング kn-keyword=e-ラーニング END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue= article-no= start-page=49 end-page=53 dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20150201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Development of a new computer-assisted technigue for efficient usage of latent heat with computer system kn-title=施設栽培における潜熱利用に関するコンピュータ利用技術の開発 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　In protected horticulture, cooling techniques with latent heat has been effective for improving the growth of various kinds of plants in the summer season. It was necessary to understand special knowledge of the VETH diagrammatic drawing for effective operation of cooling with latent heat. In order to obtain the information from VETH diagrammatic drawing, it was necessary to perform a lot of calculations. It was difficult to obtain such information simply. So, a device and software were developed for getting effective information in order to manage cooling of latent heat. The developed device and software were run on the Ubiquitous Environment Control System (UECS). The rules for controlling the environment of UECS was were set up on a web site, and an information communication technique was used for controlling the environment. The developed ventilation calculated node gathered the necessary information from the other nodes via LAN automatically. The node calculated valuable information for cooling with latent heat, including the ventilation rate, and sent the calculated values, after entering the constant parameters using an http server, which was installed in the node. The developed software was run on a personal computer. The software could be used after describing various information for calculating ventilation rate and evaporation rate at the setting file. It calculated these values, and users were shown the data using graphs and text files. As a result, we could get effective information concerning cooling latent heat fairly easily by using of the developed node and the software. en-copyright= kn-copyright= en-aut-name=YasubaKen-ichiro en-aut-sei=Yasuba en-aut-mei=Ken-ichiro kn-aut-name=安場健一郎 kn-aut-sei=安場 kn-aut-mei=健一郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学農学部 en-keyword=latent heat kn-keyword=latent heat en-keyword=computer kn-keyword=computer en-keyword=fogging kn-keyword=fogging en-keyword=ubiquitous environment control system kn-keyword=ubiquitous environment control system END start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue=5 article-no= start-page=295 end-page=302 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20141015 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Image Recognition Method to Measure Angular Velocity from Movement of a Back of Hand for Safety Education kn-title=安全教育のため手の甲によるバルブ速度測定画像認識法 en-subtitle= kn-subtitle= en-abstract=　The realization of training of virtual reality is expected to prevent the accidents caused by human factor. The benefits of training in virtual environment is a realization of training in a simulated real environment. However, there is a problem that a trainee cannot train in the simulated real environment because there is no user interface （UI） to transmit the valve operations which is basic manipulation in the industrial plant to the training system. In this study, we propose an image recognition method for developing a valve manipulation UI which aims to realize the training of valve opening manipulation in virtual environment. The method to measure the angular velocity of the circular handle of a valve utilizes the optical natural feature points obtained from the hand turning the handle. The advantage of our valve manipulation UI is that the UI can construct easily by popular products such as PC, web camera. Our method was revealed to be able to be applied to the UI of training system for worker to train valve operating manipulation which assumed fire risk because it can measure the velocity of 22.5〜90 deg/s. kn-abstract=　人的要因の事故を防止する為，仮想現実感を利用した訓練の実現が期待されている．仮想環境での訓練の利点は実環境に近い環境で訓練できる点にある．しかし，プラント内で基本操作であるバルブの操作をシステムへ伝えるユーザ・インタフェース（UIと省略）は現在なく，実環境に即した訓練ができない問題がある． 　そこで本研究では，仮想環境におけるバルブ開操作訓練を実現するバルブ操作UI開発のため，バルブの丸ハンドルの回転速度を測定する画像認識手法を提案する．本手法はバルブの丸ハンドルを回す手から取得した光学的自然特徴点を利用する．本バルブ開操作UIはPC，Webカメラといった一般的な製品を用い平易に実現できる利点がある． 　本手法は，評価実験で22.5-90deg/sを測定できる事を確認できたため，発火危険を想定したバルブ操作訓練のためのUIに適用できる事が明らかとなった． en-copyright= kn-copyright= en-aut-name=MINOWAHirotsugu en-aut-sei=MINOWA en-aut-mei=Hirotsugu kn-aut-name=箕輪弘嗣 kn-aut-sei=箕輪 kn-aut-mei=弘嗣 aut-affil-num=1 ORCID= en-aut-name=MUNESAWAYoshiomi en-aut-sei=MUNESAWA en-aut-mei=Yoshiomi kn-aut-name=宗澤良臣 kn-aut-sei=宗澤 kn-aut-mei=良臣 aut-affil-num=2 ORCID= en-aut-name=HASHIMOTOKohei en-aut-sei=HASHIMOTO en-aut-mei=Kohei kn-aut-name=橋本康平 kn-aut-sei=橋本 kn-aut-mei=康平 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学自然科学研究科 affil-num=2 en-affil= kn-affil=広島工業大学 工学部 機械システム工学科 affil-num=3 en-affil= kn-affil=（株）今仙電機製作所 en-keyword=画像認識 kn-keyword=画像認識 en-keyword=仮想現実感 kn-keyword=仮想現実感 en-keyword=ユーザ・インタフェース kn-keyword=ユーザ・インタフェース en-keyword=バルブ kn-keyword=バルブ en-keyword=プラント安全 kn-keyword=プラント安全 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=39 end-page=40 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=201311 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A Visual Learning Tool for Database Operation en-subtitle= kn-subtitle= en-abstract= kn-abstract=In this paper we propose sAccess, a web-based learning tool for database education. It focuses on introductory computer science education for high school and college. sAccess has an easy-to-use query interface for manipulating databases. Using this tool, students can learn the fundamental knowl- edge of relational database practically. In this paper, we will explain the overview of design and implementation of sAccess. en-copyright= kn-copyright= en-aut-name=NagatakiHiroyuki en-aut-sei=Nagataki en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NakanoYoshiaki en-aut-sei=Nakano en-aut-mei=Yoshiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NobeMidori en-aut-sei=Nobe en-aut-mei=Midori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TohyamaTatsuya en-aut-sei=Tohyama en-aut-mei=Tatsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KanemuneSusumu en-aut-sei=Kanemune en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Kobe Municipal High School of Science and Technology affil-num=3 en-affil= kn-affil=Osaka Prefectural Neyagawa High School affil-num=4 en-affil= kn-affil=Osaka Electro-Communication University affil-num=5 en-affil= kn-affil=Osaka Electro-Communication University en-keyword=database kn-keyword=database en-keyword=web-based learning tool kn-keyword=web-based learning tool END start-ver=1.4 cd-journal=joma no-vol=9 cd-vols= no-issue= article-no= start-page=101 end-page=110 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20131230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Teaching a writing web class based on reflective questionnaires kn-title=Web Class を利用してのライティング授業 −振り返りアンケートをもとに− en-subtitle= kn-subtitle= en-abstract= kn-abstract=　本稿は平成25年度前期の「総合英語３」（ライティング）において, Web Class を利用したライティング授業を報告するものである。Web Classは岡山大学教育開発センターIT活用教育専門委員会・e-Learning 支援室が提供する基盤システムであり，本稿の実践クラスでは，おもに課題のやりとり，教員からのフィードバック，およびピアレビューなどがもちいられた。学期末に実施した振り返りアンケートからは，上級レベルの学生は「ピアレビュー」に，初級レベルの学生は「教員からのコメントフィードバック」にWeb Class の機能としての効果を認識していることがわかった。Web Classの利用は英語ライティング授業のアクティビティーの選択肢を広げることになると思われるが，学生のレベルや指導の目的を考慮したうえで，利用が求められることもあらためて確認された。 en-copyright= kn-copyright= en-aut-name=OtoshiJunko en-aut-sei=Otoshi en-aut-mei=Junko kn-aut-name=大年順子 kn-aut-sei=大年 kn-aut-mei=順子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学言語教育センター en-keyword=Web Class kn-keyword=Web Class en-keyword=ライティング kn-keyword=ライティング en-keyword=フィードバック kn-keyword=フィードバック en-keyword=ピアレビュー kn-keyword=ピアレビュー en-keyword=振り返りアン ケート kn-keyword=振り返りアン ケート END start-ver=1.4 cd-journal=joma no-vol=55 cd-vols= no-issue=1 article-no= start-page=2 end-page=15 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20140115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Design and Implementation of an Online Tool for Database Education kn-title=データベース操作の学習が可能なオンライン学習教材の提案 en-subtitle= kn-subtitle= en-abstract=In this paper we propose "sAccess", a web-based tool for database education. It focuses on database learning activity in general education. By using sAccess, students can study the basic concepts of relational operations of some tables, such as projection, selection, and join. Students can see the source table and result table of the operation. In this paper we will show the requirements of tools for database education in general education, explain the design and implementation of sAccess and discuss the advantage of sAccess through the experiments. kn-abstract=リレーショナルデータベースに対する問合せ処理を,ウェブブラウザ上から対話的に操作できるオンライン学習教材sAccessを開発した.特徴として,射影,選択,結合などリレーショナルデータベースの基本操作に1対1対応した操作体系や,それらの処理の前後のデータテーブルを画面上で確認しながら処理を進められる点があげられる.本論文では,主に高校の共通教科「情報」などの非情報系の学習者を対象とした情報教育において,データベース学習で必要になる要件を検討し,提案するsAccessの設計と実装について説明を行う.そのうえで,従来授業などでデータベース学習に用いられてきたツールとの比較を行うことで,sAccessの利点と課題について議論する. en-copyright= kn-copyright= en-aut-name=NagatakiHiroyuki en-aut-sei=Nagataki en-aut-mei=Hiroyuki kn-aut-name=長瀧寛之 kn-aut-sei=長瀧 kn-aut-mei=寛之 aut-affil-num=1 ORCID= en-aut-name=NakanoYoshiaki en-aut-sei=Nakano en-aut-mei=Yoshiaki kn-aut-name=中野由章 kn-aut-sei=中野 kn-aut-mei=由章 aut-affil-num=2 ORCID= en-aut-name=NobeMidori en-aut-sei=Nobe en-aut-mei=Midori kn-aut-name=野部緑 kn-aut-sei=野部 kn-aut-mei=緑 aut-affil-num=3 ORCID= en-aut-name=KanemuneSusumu en-aut-sei=Kanemune en-aut-mei=Susumu kn-aut-name=兼宗進 kn-aut-sei=兼宗 kn-aut-mei=進 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=教育開発センター affil-num=2 en-affil= kn-affil=大阪電気通信大学 affil-num=3 en-affil= kn-affil=大阪電気通信大学 affil-num=4 en-affil= kn-affil=大阪電気通信大学 en-keyword=データベース教育 kn-keyword=データベース教育 en-keyword=情報教育 kn-keyword=情報教育 en-keyword=リレーショナルデータベース kn-keyword=リレーショナルデータベース en-keyword=オンライン学習教材 kn-keyword=オンライン学習教材 END start-ver=1.4 cd-journal=joma no-vol=109 cd-vols= no-issue=234 article-no= start-page=1 end-page=5 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20091009 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Bio-medical Term Extraction with Morpho-Syntactic Rules on Simple Rule Language kn-title=SRLを利用した規則ベースの感染症用語抽出 en-subtitle= kn-subtitle= en-abstract=Simple rule language, rule-based term extraction, bio-medical terms, Disease surveillance system Bio-medical term extraction is a key technology for a surveillance system of epidemic disease news from the Web. In the previous work we applied statistical learning model to extract terms from the Web site. The previous approach is good at extracting terms with high precision rates; however it is weak at extracting new terms that do not exist in the training data. Since we usually have new disease names a new term extraction approach with high coverage for unknown or low-frequent terms is needed. Recently, Simple rule Language (SRL), a rule-based word extraction language, is freely available. The SRL also has an developing environment called SRL editor. Thus we are constructing rules of bio-medical terms on the several language (such as English, Japanese, Thai and Vietnam) for the multilingual disease surveillance system. In this manuscript we confirm how we construct rules to extract Japanese bio-medical terms from Japanese news articles. kn-abstract=我々は感染症情報をWeb上から集めて提示するBioCasterシステムを構築している.感染症情報は各国のローカルニュースに速報が出ることが予測されることから英語のみならず日本語を含めたアジア言語での開発を進めている.核となる技術は感染症に関する用語を記事から見つける用語抽出であるが,既存の手法では学習データを利用した統計的学習モデルを利用して構築した.しかしながら,新たな病気など学習データに無い用語が現れた際うまく獲得できないことが予測されるため規則に基づく用語抽出システムの構築を行う.規則ベースで用語を抽出するシステムとしてSRL(Simple Rule Language)が公開されており,ユーザは語構成ならびに文脈を規則で記述することで用語を抽出できる.そこで本研究では感染症情報に必要な用語についてどのようにSRL上で定義できるかについて明らかにする. en-copyright= kn-copyright= en-aut-name=ShinnouTakashi en-aut-sei=Shinnou en-aut-mei=Takashi kn-aut-name=新納貴志 kn-aut-sei=新納 kn-aut-mei=貴志 aut-affil-num=1 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=2 ORCID= en-aut-name=NigelCollier en-aut-sei=Nigel en-aut-mei=Collier kn-aut-name=ナイジェルコリアー kn-aut-sei=ナイジェル kn-aut-mei=コリアー aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学工学部情報工学科 affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 affil-num=3 en-affil= kn-affil=国立情報学研究所 END start-ver=1.4 cd-journal=joma no-vol=2012-NL-207 cd-vols= no-issue=15 article-no= start-page=1 end-page=7 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120719 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Discussion of Possible Semantic Description for Documents Based on Analysis of Predicate-Argument Structure kn-title=述語の分析に基づく文書解析の考察 en-subtitle= kn-subtitle= en-abstract=The results of our previous work of construction of Japanese verb thesaurus revealed that a verb meaning often contains not only action or change-of-state meaning, i.e., objective meaning, but subjective meanings. To describe verb meaning, lexical conceptual structure was applied, but it does not have a place of subjective and modal meaning; then they are described using natural language embedded in an extended LCS-based schema. Modal logic gives us a description framework, but verb meanings have more complex meaning, such as event attributes, progress and possibility. In the manuscript we summarize the wide variety of verb and adjective verb meaning from the view of change-of-state and subjective meaning, then discuss a description framework of them according to modal logic study. kn-abstract=動詞間で共通する意味属性を考慮して,シソーラス上に整理した動詞項構造シソーラスを提案し,形容動詞まで拡張して分析を進めてきた.動詞項構造シソーラスの背景には語彙概念構造という状態変化を主に記述する形式を拡張してきたが,「必要だ」や「必ず?する」といった主観的な内容を記述する場所が無く,意味記述の中に自然言語で埋めることになっている.本稿では述語の分析から必要となる意味構造の要件を明らかにする.その中でも可能世界意味論に関係している点を事例をもとに明確化し,文書解析のための意味構造について考察する.さらに,人工知能で議論されてきた様相論理,動的命題,設計学,オントロジー工学との関係について概観する. en-copyright= kn-copyright= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=1 ORCID= en-aut-name=TakeuchiNao en-aut-sei=Takeuchi en-aut-mei=Nao kn-aut-name=竹内奈央 kn-aut-sei=竹内 kn-aut-mei=奈央 aut-affil-num=2 ORCID= en-aut-name=IshiharaYasuhiro en-aut-sei=Ishihara en-aut-mei=Yasuhiro kn-aut-name=石原靖弘 kn-aut-sei=石原 kn-aut-mei=靖弘 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院 affil-num=2 en-affil= kn-affil= affil-num=3 en-affil= kn-affil=岡山大学大学院 END start-ver=1.4 cd-journal=joma no-vol=3 cd-vols= no-issue= article-no= start-page=27 end-page=31 dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130308 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Web-based Interactive three-dimensional Crystal Structure Materials for Scientific Education kn-title=理科教育におけるWebベースの対話型3次元結晶構造教材 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　理科教育におけるWeb ベースの対話型3 次元結晶構造教材としてX3D 形式あるいは3D PDF を使ったシステムを比較検討した。どちらの形式もe- ラーニングシステムと高い親和性を持ち，また初学者と専門家の空間概念の把握に関するギャップを埋める教材として優れていると考えられた。データの継続使用を考えた場合，オープン規格であるX3D 形式と対応Web ブラウザを用いるシステムが適していた。一方，高品位な印刷が必要な場合は3D PDF とAdobe Reader を組み合わせたシステムが適していると考えられたが，将来に渡る継続利用を考慮した場合，このシステムはプロプライエタリである点に留意して運用しなくてはならないだろう。 en-copyright= kn-copyright= en-aut-name=YamakawaJunji en-aut-sei=Yamakawa en-aut-mei=Junji kn-aut-name=山川純次 kn-aut-sei=山川 kn-aut-mei=純次 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 en-keyword=3D PDF kn-keyword=3D PDF en-keyword=X3D kn-keyword=X3D en-keyword=結晶構造 kn-keyword=結晶構造 en-keyword=理科教材 kn-keyword=理科教材 END start-ver=1.4 cd-journal=joma no-vol=2005 cd-vols= no-issue=94 article-no= start-page=123 end-page=130 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Construction of Compositional Lexical Database Based on Lexical Conceptual Structure kn-title=分類の根拠を明示した動詞語彙概念構造辞書の構築 en-subtitle= kn-subtitle= en-abstract=This paper presents our ongoing research for constructing a Japanese verb lexicon which is founded on the theory of lexical conceptual structure (LCS). LCS provides a framework for capturing the relation between syntactic behaviors of lexical items and their semantic properties, which is useful for a range of NLP tasks including translation, paraphrasing and summarization. We discuss design issues involved in LCS dictionary development, and present an overview of the current specification of the lexicon, which is designed to allow successive future refinements. kn-abstract=本研究では語彙概念構造を利用した動詞の辞書データベースを構築する．語彙概念構造は構文上での語の振る舞いを基に意味構造を記述するもので，こうした辞書データは言語処理において特に言語生成，例えば翻訳や言い換え，要約といった応用に必須となる言語資源である．提案する辞書データは語彙概念構造のみを記述するのではなく，語彙概念構造の分析で明らかにする語の振る舞い，ならびに分析の基となる統語テストを記述するため，分類根拠がわかりやすく透明性の高い辞書データとなることが期待できる． en-copyright= kn-copyright= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=1 ORCID= en-aut-name=InuiKentaro en-aut-sei=Inui en-aut-mei=Kentaro kn-aut-name=乾健太郎 kn-aut-sei=乾 kn-aut-mei=健太郎 aut-affil-num=2 ORCID= en-aut-name=FujitaAtsushi en-aut-sei=Fujita en-aut-mei=Atsushi kn-aut-name=藤田篤 kn-aut-sei=藤田 kn-aut-mei=篤 aut-affil-num=3 ORCID= en-aut-name=TakeuchiNao en-aut-sei=Takeuchi en-aut-mei=Nao kn-aut-name=竹内奈央 kn-aut-sei=竹内 kn-aut-mei=奈央 aut-affil-num=4 ORCID= en-aut-name=AbeShuya en-aut-sei=Abe en-aut-mei=Shuya kn-aut-name=阿部修也 kn-aut-sei=阿部 kn-aut-mei=修也 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil= kn-affil=奈良先端科学技術大学院大学 affil-num=3 en-affil= kn-affil=京都大学情報学研究科 affil-num=4 en-affil= kn-affil= affil-num=5 en-affil= kn-affil=奈良先端科学技術大学院大学 END start-ver=1.4 cd-journal=joma no-vol=2006 cd-vols= no-issue=94 article-no= start-page=13 end-page=20 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060912 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Construction of rule-based model for semantic role labeling with the EDR thesaurus and an LCS dictionary kn-title=名詞の概念体系を利用した規則に基づく意味役割付与モデルの構築 en-subtitle= kn-subtitle= en-abstract=We present a rule-based model for semantic role labelingbecause semantic role labels should be assigned by means of metoric relationsips between mouns and vers. The purpose of this resarch is to reveal the this resarch is to reveal the restritional and preference rules between nouns and verbs. Our model uses the EDR thesaurus as semantics of nouns, and a lexical conceptual structure dictionary as verb semantics. Experimental results show that dealing with systemantic nominal categorization is the key to improve the accuracy of semantic role labeling. kn-abstract=本稿では名詞の概念体系辞書と述語のもつ語の概念構造を用いた規則ベースの意味役割付与モデルの構築を提案する．意味役割は名詞と述語との関係から決定されることから,本研究では述語の持つイベント構造と述語がとる名詞との間にどのようなメカニズムが存在するのかを明らかにすることを目標とする.新聞コーバスを対象とした評価実験から,名詞間の概念の類似度を正しく計ること,機能語の単位を正しく取り出すことが精度向上へのポイントであることが明らかになった． en-copyright= kn-copyright= en-aut-name=ShimomuraTakuya en-aut-sei=Shimomura en-aut-mei=Takuya kn-aut-name=下村拓也 kn-aut-sei=下村 kn-aut-mei=拓也 aut-affil-num=1 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=2006 cd-vols= no-issue=94 article-no= start-page=35 end-page=42 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060912 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Web Search Result Clustering Based on Structure of Compound Nouns kn-title=複合名詞に着目したWeb検索結果のクラスタリング en-subtitle= kn-subtitle= en-abstract=In this paper, we propose a aclustering method based on structure of compound nouns. Japanese compound nouns usually provide concrete concepts, thus we can assume that compound nouns must be a good clue to index documents for Web document clustering. The other benefit of using compound nouns is their compositional structure that can ve divided into sub concepts. This indicates that we can construct hierarchical Web document clustering based on their strcture. From the practical experiments of constructing hierarchical clusters on the results of a Web search engine, we succeeded in showing that the clearly lusterized web documents with understandable hierarchical indexes of compound nouns. kn-abstract=本稿では複合名詞に着目したWeb検索結果のクラスタリング手法を提案する．本手法では検索結果のタイトルと要約を利用し，階層的で一つの検索結果が複数のクラスタに含まれることを認めるクラスタリングを行う．本手法は次の２つの仮説に基づいている．1)複合名詞は固有の概念を表すため，文書を特徴付けやすい．2)複合名詞間の語構成関係を利用して，部分複合による類概念，および上位下位関係のクラスラベルを作成することで見通しの良いＷｅｂ文書の分類ができる．実験の結果，複合名詞の構造は分かりやすいクラスタ構造の形成に利用でき，また自然なラベル付けに有効であった．このことから，複合名詞は検索結果全体を見渡すためのよいインデックスであると言える． en-copyright= kn-copyright= en-aut-name=HiraoKazuki en-aut-sei=Hirao en-aut-mei=Kazuki kn-aut-name=平尾一樹 kn-aut-sei=平尾 kn-aut-mei=一樹 aut-affil-num=1 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=2006 cd-vols= no-issue=124 article-no= start-page=55 end-page=60 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20061122 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Method for Extracting Composite Terms from Japanese Domain Corpora kn-title=日本語専門分野テキストコーパスからの複合語用語の抽出 en-subtitle= kn-subtitle= en-abstract=Term extraction is one of the most important application of natural language processing technologies. Statistic criteria are widely adopted to evaluate the termhood of the extracted candidates. However, it is difficult to evaluate the termhood of less frequent candidates. In this study we propose a method for Japanese composite term extraction in which unproper morpheme patterns are eliminated. Using the new method, high precision of term extraction can be attained for Japanese composite terms. kn-abstract=テキストコーパスからの用語抽出は、自然言語処理技術の重要な応用である。従来テキストコーパスから用語候補を抽出する方法として、主として候補出現に関わる統計的指標を用いて用語性を判定する方法が採用されて来たが、統計的手法では出現頻度の低い候補についての判定が困難であった。今回の発表では、複合語に注目し、用語性を損なう形態素出現パターンを排除する形での用語候補抽出を行うことにより、高い精度で複合語用語抽出が可能となることを示す。 en-copyright= kn-copyright= en-aut-name=KoyamaTeruo en-aut-sei=Koyama en-aut-mei=Teruo kn-aut-name=小山照夫 kn-aut-sei=小山 kn-aut-mei=照夫 aut-affil-num=1 ORCID= en-aut-name=KageuraKyo en-aut-sei=Kageura en-aut-mei=Kyo kn-aut-name=影浦峡 kn-aut-sei=影浦 kn-aut-mei=峡 aut-affil-num=2 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=国立情報学研究所 affil-num=2 en-affil= kn-affil=東京大学大学院教育学研究科 affil-num=3 en-affil= kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=2007 cd-vols= no-issue=76 article-no= start-page=49 end-page=54 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070724 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Hierarchical Structurization of Japanese Composite Terms based on Nesting Relations kn-title=日本語複合語用語の入れ子関係に基づく階層的体系化 en-subtitle= kn-subtitle= en-abstract=We introduce a method for structurizing term candidates extracted from a Japanese domain corpus, based on nesting relations between the candidates. From the nesting relations, we can infer hypernym-hyponym relations and related term relations. Arranging both relations separately, we can get clearer hierarchical relations. kn-abstract=日本語専門分野テキストコーパスから抽出された日本語複合語用語候補について、候補間の入れ子関係から階層関係を推定し、体系化を行う試みについて発表する。入れ子関係からは、上位語−下位語関係、および関連語関係を推定することが可能であるが、それぞれの関係を別途整理することにより、見通しの良い階層表示が可能となることを示す。 en-copyright= kn-copyright= en-aut-name=KoyamaTeruo en-aut-sei=Koyama en-aut-mei=Teruo kn-aut-name=小山照夫 kn-aut-sei=小山 kn-aut-mei=照夫 aut-affil-num=1 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=国立情報学研究所 affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 en-keyword=用語抽出 kn-keyword=用語抽出 en-keyword=用語体系化 kn-keyword=用語体系化 en-keyword=用語階層関係 kn-keyword=用語階層関係 END start-ver=1.4 cd-journal=joma no-vol=2007 cd-vols= no-issue=113 article-no= start-page=31 end-page=38 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20071119 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Toward Construction of Verb Thesaurus for Paraphrasing Metaphor Expressions on the Basis of Metaphor Analysis kn-title=メタファ分析に基づく置換可能な動詞カテゴリの作成 en-subtitle= kn-subtitle= en-abstract=Metaphor expression, especially consisting of a noun and verb, is irregular expression thus it is not easy to be dealt with in natural language applications such as machine translation, summarization, and document understanding. We believe it is important that metaphor expressions should be paraphrased into normalized basic expressions in order to extract a fact embedded in the expression: for example a metaphor expression “the wind plays” can be paraphrased into a basic expression “the wind blows”. In order to realize this task, in this paper we propose a verb thesaurus organized on the basis of semantic coherency for verbs. From the work of manual construction of a thesaurus on 50 verbs we discuss the possibility of our approach. kn-abstract=動詞と名詞による表現において動詞の意味のずれにより生じるメタファが機械翻訳や要約などの自然言語処理や文章の理解において問題となる場合がある。そのメタファに内在する事実を扱うためには、前もって一般的な表現へと変換処理をする必要があると考えられる。例えば「風が遊ぶ」というメタファを「風が吹く」などの一般的な表現に言い換える処理が必要であろう。本稿ではこの処理に必要となる動詞カテゴリの作成を提案する。実際に 50 の動詞について類似性に基づきカテゴリを作成し考察をすることで、置換可能な動詞間の類似性や共起する名詞の扱い方が動詞カテゴリの網羅性と信頼性の向上にどのように関わるかを明らかにする。 en-copyright= kn-copyright= en-aut-name=IchinoseMitsuru en-aut-sei=Ichinose en-aut-mei=Mitsuru kn-aut-name=一ノ瀬充 kn-aut-sei=一ノ瀬 kn-aut-mei=充 aut-affil-num=1 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=2007 cd-vols= no-issue=113 article-no= start-page=39 end-page=44 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20071119 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Constrution of Semantic Verb Class Using Graph-Based Co-clustering Approach kn-title=グラフ構造に基づく同時クラスタリングを利用した動詞の属性クラスの抽出 en-subtitle= kn-subtitle= en-abstract=This paper presents our ongoing research for clustering Japanese verbs for constructing Japanese verb lexicon which is founded on the theory of lexical conceptual structure (LCS). The key issue of this research is how to extract a core cluster of Japanese verbs with a highly relating cluster of nouns because not only verbs but also nouns are polysemouns words. In this paper we applied an approach of co-clustering on the basis of graph sctructure into clustering task of verbs and nouns, and present experimental results on Japanese Verb-Case-Noun data from both large Web corpus and Maichini news paper corpus from 1991 to 1998. kn-abstract=テキスト中に現れる動詞と名詞の格関係を利用して動詞のクラスタリングを行い意味的に類似の集合の構築を目指す．ここでの問題は名詞と動詞はそれぞれ多義であり，かつその語義が観測可能でないことである．本稿ではある名詞の集合と動詞の集合がなすクラスタがある１つのクラスタ (ある潜在的な意味クラスタ) に属すると考え，同時共起クラスタリングを適用する．Web の５億文のデータから獲得された格フレームデータ，ならびに毎日新聞 91 から 98 年を利用して得られた動詞集合について評価することで，本手法により大量のデータがあれば質の良い動詞集合が得られることを明らかにする． en-copyright= kn-copyright= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=2008 cd-vols= no-issue=4 article-no= start-page=87 end-page=92 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080122 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An evaluation of document set similarity based on morpheme occurence patterns kn-title=用語クラスタリングに基づく部分研究領域推定と用語分類 en-subtitle= kn-subtitle= en-abstract=Term classification associate to research sub-domain is an important approach for systematized classification of term candidates extracted from text corpora. The authors have developed a method which identify some of the important research sub-domains in research abstract corpora. The authors also proved that relatively frequent term candidates extracted from the corpus can be related to identified sub-domains. kn-abstract=研究抄録テキストコーパスから抽出された用語候補を体系的に整理する一つの有力な方法として、部分研究領域に関連付けた用語の分類を考えることができる。本研究では、動詞概念との共起に基づく用語クラスタリングによって、特定研究分野のいくつかの部分研究領域が同定できることを示すとともに、同定された部分領域との関連により、テキストコーパスから抽出された用語候補の分類が可能であることを示す。 en-copyright= kn-copyright= en-aut-name=KoyamaTeruo en-aut-sei=Koyama en-aut-mei=Teruo kn-aut-name=小山照夫 kn-aut-sei=小山 kn-aut-mei=照夫 aut-affil-num=1 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=国立情報学研究所 affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=2008 cd-vols= no-issue=113 article-no= start-page=51 end-page=56 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20081119 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An evaluation of document set similarity based on morpheme occurence patterns kn-title=形態素出現パタンに基づく文書集合類似性評価 en-subtitle= kn-subtitle= en-abstract=We can assume that two different document sets may show similar morpheme occurrence patterns, if the sets both discuss about similar topics with similar discussion manners. In this paper, the authors show the occurrence patterns of morphemes really indicates the similarity of the sets. The authors also show the difference of the patterns in both sets indicate the difference of topics or discussion manner between the sets. The authors also show how to find key morphemes that indicate the similarity or difference of the sets. kn-abstract=類似したテーマを類似した論述構造で扱う文書を集めた文書集合同士では、共通 した形態素利用パタンが出現すると予想される。一方で、形態素出現傾向の相違は、文書集合の間で扱われるテーマあるいは論述構造の相違を示すものと考えられる。本研究では、異なる学会の研究抄録を集めた文書集合について、形態素出現傾向が集合間の類似性や相違を評価する指標として有効であることを確認するとともに、どの形態素が文書集合間の類似性ないしは相違性に寄与しているかを評価する方法について発表する。 en-copyright= kn-copyright= en-aut-name=KoyamaTeruo en-aut-sei=Koyama en-aut-mei=Teruo kn-aut-name=小山照夫 kn-aut-sei=小山 kn-aut-mei=照夫 aut-affil-num=1 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=国立情報学研究所 affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=2009-NL-193 cd-vols= no-issue=13 article-no= start-page=1 end-page=6 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20090921 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Term Extraction based on the Forward and Backward Connectivities of Candidates kn-title=候補の接続関係を考慮した複合語用語抽出 en-subtitle= kn-subtitle= en-abstract=In composite term extraction problems, it is important to extract candidates of relatively low occurrences in the corpora, with enough precision. In previous works, we have developed a method which can extract term candidates of low occurrences, using the revised classification of Japanese morphemes. In this paper, we propose a improved method considering forward and backward connective relations of candidates. Using the method, composite term candidates of less occurrences can be extracted with high precision. kn-abstract=テキストコーパスからの複合語用語抽出においては、抽出精度を低下させることなく、出現頻度の低い候補まで抽出することが重要である。従来主として用いられてきた統計的手法では、特に低頻度の用語候補の抽出に問題があった。我々はこれまでに用語候補となる複合語を構成する形態素の細分類に応じた位置制約を設定することにより、低頻度の候補まで抽出する方法を提案して来た。今回の発表では、この手法を改善し、多くの用語は文書中に少なくとも一回は提題的な形で出現するという予測の下に、候補となる形態素並びの前後接続関係に制約を設ける方法を提案する。実際にこの方法を適用することによりさらに低頻度の候補まで、抽出精度を落とすことなく取り出せることを確認した。 en-copyright= kn-copyright= en-aut-name=KoyamaTeruo en-aut-sei=Koyama en-aut-mei=Teruo kn-aut-name=小山照夫 kn-aut-sei=小山 kn-aut-mei=照夫 aut-affil-num=1 ORCID= en-aut-name=TakeuchiKoichi en-aut-sei=Takeuchi en-aut-mei=Koichi kn-aut-name=竹内孔一 kn-aut-sei=竹内 kn-aut-mei=孔一 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=国立情報学研究所 affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=52 cd-vols= no-issue=3 article-no= start-page=1348 end-page=1356 dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110315 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A MAC-address Relaying NAT Router for Host Identification from Outside of Internal Network kn-title=内部ネットワーク上のホストを外部から識別するためのMACアドレス中継型NATルータ en-subtitle= kn-subtitle= en-abstract=As an alleviation method against IPv4 address exhaustion problem, NAT (Network Address Translation) has been commonly used. Since NAT allows many internal hosts to share one single global IP address, it can save the number of required global IP addresses. However, with NAT, each internal host cannot be identified from the external network. Consequently, if access control system on external network would permit network access from one internal host, it automatically would permit all network access from any other internal hosts as well, for example. In this paper, we propose a NAT router with MAC address relaying function that copies the source MAC address of receiving frames sent by internal hosts into frames sent to the external network since source MAC addresses, which are the sender identifiers in data link layer, are basically unused except for MAC address learning function of layer 2 switches. According to the results of experiments, we confirmed that the prototype NAT router with MAC address relaying function allows access to external networks by internal hosts to be controlled individually based on MAC address and obtains high throughput as well. kn-abstract=IPv4アドレスの枯渇問題の軽減策の1つとして，NAT（Network Address Translation）がある．NATは複数の内部ホストが1つのグローバルIPアドレスを共用できるため，必要なグローバルIPアドレスの数を節約できる．しかし，外部ネットワーク側では個々の内部ホストを識別できないため，たとえば外部ネットワーク側でアクセス制御を行うと，1台の内部ホストが外部ネットワークに対するアクセス許可を受けただけで他の内部ホストまで外部ネットワークにアクセス可能な状態になるなどの問題が生じる．そこで，本論文ではデータリンク層での送信元識別子である送信元MACアドレスが基本的にはレイヤ2機器のMACアドレス学習機能にしか使われていない点に着目し，内部ホストから送信されたフレームに含まれる送信元MACアドレスをそのまま外部ネットワーク側に中継する機能を持つNATルータを提案する．本提案に基づいて試作したNATルータを評価した結果，MACアドレスに基づいて内部ホストを個別にアクセス制御でき，また十分なスループットが得られることを確認した． en-copyright= kn-copyright= en-aut-name=YamaiNariyoshi en-aut-sei=Yamai en-aut-mei=Nariyoshi kn-aut-name=山井成良 kn-aut-sei=山井 kn-aut-mei=成良 aut-affil-num=1 ORCID= en-aut-name=MurakamiRyo en-aut-sei=Murakami en-aut-mei=Ryo kn-aut-name=村上亮 kn-aut-sei=村上 kn-aut-mei=亮 aut-affil-num=2 ORCID= en-aut-name=OkayamaKiyohiko en-aut-sei=Okayama en-aut-mei=Kiyohiko kn-aut-name=岡山聖彦 kn-aut-sei=岡山 kn-aut-mei=聖彦 aut-affil-num=3 ORCID= en-aut-name=NakamuraMotonori en-aut-sei=Nakamura en-aut-mei=Motonori kn-aut-name=中村素典 kn-aut-sei=中村 kn-aut-mei=素典 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学情報統括センター affil-num=2 en-affil= kn-affil=岡山大学大学院自然科学研究科 affil-num=3 en-affil= kn-affil=岡山大学情報統括センター affil-num=4 en-affil= kn-affil=国立情報学研究所 END start-ver=1.4 cd-journal=joma no-vol=40 cd-vols= no-issue=2 article-no= start-page=205 end-page=214 dt-received= dt-revised= dt-accepted= dt-pub-year=1928 dt-pub=19280229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=小動脉竝ニ毛細血管ニ及ボス藥劑ノ作用ニ就テ kn-title=On the action of some drugs upon the arterioles and capillaries en-subtitle= kn-subtitle= en-abstract=毛細血管ノ運動(收縮竝ニ擴大)ハ受働的ニシテ夫レト相連續セル小動脉ノ收縮或ハ擴大ノ状態ニヨリテ左右セラレ小動脉ノ擴大ハ毛細血管ニ於ケル壓ノ上昇ヲ來タシタメニ該毛細血管ハ受働的ニ擴大ヲ來タシ壓ノ下降ニ際シテ自身ノ彈力ニヨリテ元ニ復ス事ハ一般ニ信ゼラルル事實ナリ. 然ルニ又一方ニ於テ毛細血管ノ運動ハ單ニ壓ニノミ依ル受働的ノモノニ非ズシテ自働的ニ收縮及ビ擴大ヲ起スト云フ多クノ事實ガ認メラレ其後諸種藥劑ニ依リテ毛細血管ガ血壓ニ關係ナク反應ヲ起ス事實ヲ知ルニ至レリ.又近時或藥品ニ對シテ小動脉及ビ毛細血管ガ反對ノ作用ヲ現ハス事ヲ發見セリ例ヘバAdrenalinハ小動脉ニ對シ收縮性ニ働ラクモ毛細血管ハ之ニ反シ擴大ヲ起ス又Histaminハ小動脉ヲ擴大セシムルモ毛細血管ニハ何等ノ影響ヲ及ボサズ. 予ハ五六ノ藥劑ヲ用ヒテ小動脉竝ニ毛細血管ニ對シ果シテ如何ナル作用ヲ及ボスカヲ見ント欲シ次ノ實驗ヲ行ヘリ即チ蛙ノ蹼膜,腸間膜竝ニ膀胱壁ノ小動脉及ビ毛細血管ヲ顯微鏡下ニ觀察シナガラ各藥劑各種溶液ヲ滴下シ小動脉及ビ毛細管ノ變化ヲ見タリ而シテ次ノ成績ヲ得タリ. 1.芥子油ハ小動脉及ビ毛細血管ヲ共ニ著シク擴大セシム而シテ毛細血管ノ擴大作用ハ血壓ニ無關係ナル事ヲ確カメタリ. 2.「グアニヂン」ニ於テハ0.5%以上ノ濃度ニ於テハ小動脉竝ニ毛細管ヲ共ニ收縮セシムルモ1.0-4.0%ニテハ之ニ反シ擴大作用ヲ有ス. 3.「アドレナリン」ハ小動脉ヲ收縮セシムルモ毛細管ハ反ツテ之ヲ擴大セシム. 4.「ピツイトリン」ハ小動脉ヲ收縮セシメ同時ニ毛細血管ヲ擴大セシム而シテ此作用ハ「アドレナリン」ニ比シ其持續性弱シ. 5.「カフエイン」ハ小動脉竝毛細管ヲ共ニ擴大セシム而シテ毛細管ノ擴大ハ血壓ニ無關係ナリ. 6.「ナトリウム」鹽類ハ概ネ擴大ヲ起スモ「カリウム」鹽類ハ之ヲ收縮セシム「カルチウム」鹽類竝ニ「マグネシウム」鹽類ハ共ニ小動脉竝ニ毛細血管ヲ擴大セシム. 7.「ハイドロキノーン」,「ピロガロール」「フロロガルチン」ハ小動脉竝ニ毛細血管ニ對シ著シキ擴大ヲ起サシム. kn-abstract=1. Direct application of the mustard-oil to the web, mesentery and bladder wall of frog, caused remarkable dilatation both on the arterioles and capillaries. And capillaries are dilated independently of variation in the arterial blood pressure. 2. A solution of guanidin stronger than 5.0 p. c. has constricting effect upon the arterioles and capillaries, while weak solution (1.0-4.0 p. c.) causes dilatation of the arterioles and capillaries. 3. Adrenalin has contractive effect upon the arterioles but it shows, on the other hand, dilatation of capillaries indepent of variation in the arterial blood pressure. 4. Pituitrin causes contraction of the arterioles, on the contrary, capillaries are always dilated. Its contractive (upon the arterioles) and dilator effect (upon the capillaries) are weaker than that produced with adrenalin. 5. Caffein shows dilator effect both on the arterioles and capillaries. The dilatation of capillaries is independent of variation in the arterial blood pressure. 6. Isotonic solution (with 0.65 p. c. NaCL) of NaNo3, NaNO2 and Na2HPO4 causes slight dilatation of the arterioles and capillaries, while kalium salts (t. i. KCLO, KNO3, KBr etc.) contraction. Calcium salts and magnecium salts have dilator effect both on the arterioles and capillaries. Some organic substances which have reducing ability, have dilator effect upon the arterioles and capillaries. en-copyright= kn-copyright= en-aut-name=OkadaMasanori en-aut-sei=Okada en-aut-mei=Masanori kn-aut-name=岡田正矩 kn-aut-sei=岡田 kn-aut-mei=正矩 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=Physiological Department of University Okayama END start-ver=1.4 cd-journal=joma no-vol=49 cd-vols= no-issue=11 article-no= start-page=2143 end-page=2148 dt-received= dt-revised= dt-accepted= dt-pub-year=1937 dt-pub=19371130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=More Facts about Antidromic Action kn-title=逆流作用(Antidromic action)ニ對スル知見補遺 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The author made experiments to find out wheter the dilation of blood-vessels of a frog's webs is really due to the antidromic action or not when mustard oil is applied to the N. ischiadicus of the amphibian. The results are as follows: 1. Cut the N. ischiadicus at the central part before it unites with the R. communicans, making the nerve fall into degeneration, and then apply mustard oil to it, and you will see that the blood-vessels contracts. 2. Cut R. communicans, making it fall into degeneration, and then apply mustard oil to the nerve, and you will see that the blood-vessels dilates. From the above stated facts, it is plain that the dilation of the blood-vessels of a frog's webs is due to the antidromic action. en-copyright= kn-copyright= en-aut-name=KawamuraKeniti en-aut-sei=Kawamura en-aut-mei=Keniti kn-aut-name=河村謙一 kn-aut-sei=河村 kn-aut-mei=謙一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學生理學教室 END start-ver=1.4 cd-journal=joma no-vol=52 cd-vols= no-issue=7 article-no= start-page=1664 end-page=1674 dt-received= dt-revised= dt-accepted= dt-pub-year=1940 dt-pub=19400731 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=On the Diuretic Action of the Extractum of Radicis Phytolaccae (Phytolacca esculenta), Extracts of several Plants and some Drugs. (1. Part.) On the Diuretic Action of the Extractum of Radicis Phytolaccae (Phytolacca esculenta). kn-title=各種植物及ビ2, 3藥物ノ利尿作用ニ就テ（第1報）「商陸エキス」ノ利尿作用ニ就テ en-subtitle= kn-subtitle= en-abstract= kn-abstract=By the perfusion method through the kidney of the toad following results were obtained. 1) When the Extr. of Rad. Phytol. is added to the perfusing fluid, it increases distinctly the flow of urine. 2) Conversely, the addition of potassium salt, which will be contained abundantly in Rad. Phytol., brings, firstly, the remarkable decrease of the urine flow, and then it may increase slightly. 3) Ash of the Rad. Phytol. dissolved in Ringer's solution decreases the urine flow remarkably at first, and then it may increase. 4) When the Extr. of Rad. Phytol. is applied in drops to the exposed kidney of frog, causes dilatation of glomerular capillaries; the circulation in them becomes more rapid, i.e. the quantity of blood which flows through them increases, and a number of glomeruli, hitherto invisible, becomes visible. The application of this extract in drops on the web of frog dilates its blood-capillaries and increases the blood-flows through them. 5) But the solution of potassium salt used, or the ash of the Rad. Phytol. causes contraction of glomerular capillaries and capillaries of web of frog. The blood-flows in the capillaries become remarkably slow, i.e. the quantity of blood which flows through them decreases. The glomeruli, hitherto activ, becomes stationary and visible number of glomeruli diminishes. 6) The measurement of the freezing-point revealed that the osmotic pressure of the Extr. of Rad. Phytol. used was not very different from the normal Ringer's solution. 7) By the flame-reaction it was ascertained that potassium and sodium salts were contained in the Rad. Phytol. 8) Diuretic action of Rad. Phytol. is due to some organic substance, which causes dilatation of capillaries of glomerulus and web of frog. Potassium salt which is contained in Rad. Phytol. makes some additional action through hydraemia. en-copyright= kn-copyright= en-aut-name=MasuzawaHiromu en-aut-sei=Masuzawa en-aut-mei=Hiromu kn-aut-name=益澤博 kn-aut-sei=益澤 kn-aut-mei=博 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山醫科大學生理學教室 END start-ver=1.4 cd-journal=joma no-vol=552 cd-vols= no-issue=3 article-no= start-page=292 end-page=328 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200511 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Design and performance of the ABCD3TA ASIC for readout of silicon strip detectors in the ATLAS semiconductor tracke en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The ABCD3TA is a 128-channel ASIC with binary architecture for the readout of silicon strip particle detectors in the Semiconductor Tracker of the ATLAS experiment at the Large Hadron Collider (LHC). The chip comprises fast front-end and amplitude discriminator circuits using bipolar devices, a binary pipeline for first level trigger latency, a second level derandomising buffer and data compression circuitry based on CMOS devices. It has been designed and fabricated in a BiCMOS radiation resistant process. Extensive testing of the ABCD3TA chips assembled into detector modules show that the design meets the specifications and maintains the required performance after irradiation up to a total ionising dose of 10 Mrad and a 1-MeV neutron equivalent fluence of 2×1014 n/cm2, corresponding to 10 years of operation of the LHC at its design luminosity. Wafer screening and quality assurance procedures have been developed and implemented in large volume production to ensure that the chips assembled into modules meet the rigorous acceptance criteria.

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en-aut-mei=P W kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=123 ORCID= en-aut-name=MorrisseyM en-aut-sei=Morrissey en-aut-mei=M kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=124 ORCID= en-aut-name=MurrayW J en-aut-sei=Murray en-aut-mei=W J kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=125 ORCID= en-aut-name=PhillipsP W en-aut-sei=Phillips en-aut-mei=P W kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=126 ORCID= en-aut-name=TyndelM en-aut-sei=Tyndel en-aut-mei=M kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=127 ORCID= en-aut-name=VillaniE G en-aut-sei=Villani en-aut-mei=E G kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=128 ORCID= en-aut-name=CosgroveD P en-aut-sei=Cosgrove en-aut-mei=D P kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=129 ORCID= en-aut-name=DorfanD E en-aut-sei=Dorfan en-aut-mei=D E kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=130 ORCID= en-aut-name=GrilloA A en-aut-sei=Grillo en-aut-mei=A A kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=131 ORCID= en-aut-name=KachiguineS en-aut-sei=Kachiguine en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=132 ORCID= en-aut-name=RosenbaumF en-aut-sei=Rosenbaum en-aut-mei=F kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=133 ORCID= en-aut-name=SadrozinskiH F. -W en-aut-sei=Sadrozinski en-aut-mei=H F. -W kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=134 ORCID= en-aut-name=SeidenA en-aut-sei=Seiden en-aut-mei=A kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=135 ORCID= en-aut-name=SpencerE en-aut-sei=Spencer en-aut-mei=E kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=136 ORCID= en-aut-name=WilderM en-aut-sei=Wilder en-aut-mei=M kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=137 ORCID= en-aut-name=AkimotoT en-aut-sei=Akimoto en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=138 ORCID= en-aut-name=HaraK en-aut-sei=Hara en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=139 ORCID= en-aut-name=TanizakiK en-aut-sei=Tanizaki en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=140 ORCID= en-aut-name=BingeforsN en-aut-sei=Bingefors en-aut-mei=N kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=141 ORCID= en-aut-name=BrennerR en-aut-sei=Brenner en-aut-mei=R kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=142 ORCID= en-aut-name=EkelofT en-aut-sei=Ekelof en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=143 ORCID= en-aut-name=EklundL en-aut-sei=Eklund en-aut-mei=L kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=144 ORCID= en-aut-name=BernabeuJ en-aut-sei=Bernabeu en-aut-mei=J kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=145 ORCID= en-aut-name=CiveraJ V en-aut-sei=Civera en-aut-mei=J V kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=146 ORCID= en-aut-name=CostaM J en-aut-sei=Costa en-aut-mei=M J kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=147 ORCID= en-aut-name=FusterJ en-aut-sei=Fuster en-aut-mei=J kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=148 ORCID= en-aut-name=GarciaC en-aut-sei=Garcia en-aut-mei=C kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=149 ORCID= en-aut-name=Garcia-NavarroJ E en-aut-sei=Garcia-Navarro en-aut-mei=J E kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=150 ORCID= en-aut-name=Gonzalez-SevillaS en-aut-sei=Gonzalez-Sevilla en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=151 ORCID= en-aut-name=LacastaC en-aut-sei=Lacasta en-aut-mei=C kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=152 ORCID= en-aut-name=LlosaG en-aut-sei=Llosa en-aut-mei=G kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=153 ORCID= en-aut-name=Marti-GarciaS en-aut-sei=Marti-Garcia en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=154 ORCID= en-aut-name=ModestoP en-aut-sei=Modesto en-aut-mei=P kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=155 ORCID= en-aut-name=SanchezF J en-aut-sei=Sanchez en-aut-mei=F J kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=156 ORCID= en-aut-name=SospedraL en-aut-sei=Sospedra en-aut-mei=L kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=157 ORCID= en-aut-name=VosM en-aut-sei=Vos en-aut-mei=M kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=158 ORCID= affil-num=1 en-affil= kn-affil=Instituto de Microelectronica de Barcelona, IMB-CNM, CSIC, Barcelona, Spain affil-num=2 en-affil= kn-affil=Instituto de Microelectronica de Barcelona, IMB-CNM, CSIC, Barcelona, Spain affil-num=3 en-affil= kn-affil=Instituto de Microelectronica de Barcelona, IMB-CNM, CSIC, Barcelona, Spain affil-num=4 en-affil= kn-affil=Instituto de Microelectronica de Barcelona, IMB-CNM, CSIC, Barcelona, Spain affil-num=5 en-affil= kn-affil=Instituto de Microelectronica de Barcelona, IMB-CNM, CSIC, Barcelona, Spain affil-num=6 en-affil= kn-affil=Instituto de Microelectronica de Barcelona, IMB-CNM, CSIC, Barcelona, Spain affil-num=7 en-affil= kn-affil=Instituto de Microelectronica de Barcelona, IMB-CNM, CSIC, Barcelona, Spain affil-num=8 en-affil= kn-affil=Instituto de Microelectronica de Barcelona, IMB-CNM, CSIC, Barcelona, Spain affil-num=9 en-affil= kn-affil=University of Bergen, Bergen, Norway affil-num=10 en-affil= kn-affil=University of Bergen, Bergen, Norway affil-num=11 en-affil= kn-affil=University of Bergen, Bergen, Norway affil-num=12 en-affil= kn-affil=University of Bergen, Bergen, Norway affil-num=13 en-affil= kn-affil=University of Bergen, Bergen, Norway affil-num=14 en-affil= kn-affil=Lawrence Berkeley Laboratory and University of California, Berkeley, California, USA affil-num=15 en-affil= kn-affil=Lawrence Berkeley Laboratory and University of California, Berkeley, California, USA affil-num=16 en-affil= kn-affil=Lawrence Berkeley Laboratory and University of California, Berkeley, California, USA affil-num=17 en-affil= kn-affil=Lawrence Berkeley Laboratory and University of California, Berkeley, California, USA affil-num=18 en-affil= kn-affil=Lawrence Berkeley Laboratory and University of California, Berkeley, California, USA affil-num=19 en-affil= kn-affil=Lawrence Berkeley Laboratory and University of California, Berkeley, California, USA affil-num=20 en-affil= kn-affil=Lawrence Berkeley Laboratory and University of California, Berkeley, California, USA affil-num=21 en-affil= kn-affil=Lawrence Berkeley Laboratory and University of California, Berkeley, California, USA affil-num=22 en-affil= kn-affil=School of Physics and Astronomy, The University of Birmingham, Birmingham, UK affil-num=23 en-affil= kn-affil=School of Physics and Astronomy, The University of Birmingham, Birmingham, UK affil-num=24 en-affil= kn-affil=School of Physics and Astronomy, The University of Birmingham, Birmingham, UK affil-num=25 en-affil= kn-affil=School of Physics and Astronomy, The University of Birmingham, Birmingham, UK affil-num=26 en-affil= kn-affil=School of Physics and Astronomy, The University of Birmingham, Birmingham, UK affil-num=27 en-affil= kn-affil=School of Physics and Astronomy, The University of Birmingham, Birmingham, UK affil-num=28 en-affil= kn-affil=School of Physics and Astronomy, The University of Birmingham, Birmingham, UK affil-num=29 en-affil= kn-affil=School of Physics and Astronomy, The University of Birmingham, Birmingham, UK affil-num=30 en-affil= kn-affil=School of Physics and Astronomy, The University of Birmingham, Birmingham, UK affil-num=31 en-affil= kn-affil=Cavendish Laboratory, Cambridge University, Cambridge, UK affil-num=32 en-affil= kn-affil=Cavendish Laboratory, Cambridge University, Cambridge, UK affil-num=33 en-affil= kn-affil=Cavendish Laboratory, Cambridge University, Cambridge, UK affil-num=34 en-affil= kn-affil=Cavendish Laboratory, Cambridge University, Cambridge, UK affil-num=35 en-affil= kn-affil=Cavendish Laboratory, Cambridge University, Cambridge, UK affil-num=36 en-affil= kn-affil=Cavendish Laboratory, Cambridge University, Cambridge, UK affil-num=37 en-affil= kn-affil=Cavendish Laboratory, Cambridge University, Cambridge, UK affil-num=38 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=39 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=40 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=41 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=42 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=43 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=44 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=45 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=46 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=47 en-affil= kn-affil=CERN, European Organization for Nuclear Research, Geneva, Switzerland affil-num=48 en-affil= kn-affil=Faculty Physics and Applied Computer Science, AGH University Science Technology, Krakow, Poland affil-num=49 en-affil= kn-affil=Faculty Physics and Applied Computer Science, AGH University Science Technology, Krakow, Poland affil-num=50 en-affil= kn-affil=Faculty Physics and Applied Computer Science, AGH University Science Technology, Krakow, Poland affil-num=51 en-affil= kn-affil=Faculty Physics and Applied Computer Science, AGH University Science Technology, Krakow, Poland affil-num=52 en-affil= kn-affil=Faculty Physics and Applied Computer Science, AGH University Science Technology, Krakow, Poland affil-num=53 en-affil= kn-affil=The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland affil-num=54 en-affil= kn-affil=The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland affil-num=55 en-affil= kn-affil=The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland affil-num=56 en-affil= kn-affil=The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland affil-num=57 en-affil= kn-affil=The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland affil-num=58 en-affil= kn-affil=The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland affil-num=59 en-affil= kn-affil=The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland affil-num=60 en-affil= kn-affil=The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland affil-num=61 en-affil= kn-affil=The Henryk Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland affil-num=62 en-affil= kn-affil=Max-Planck-Institut fur Physik, Munchen, Germany affil-num=63 en-affil= kn-affil=Max-Planck-Institut fur Physik, Munchen, Germany affil-num=64 en-affil= kn-affil=Max-Planck-Institut fur Physik, Munchen, Germany affil-num=65 en-affil= kn-affil=Max-Planck-Institut fur Physik, Munchen, Germany affil-num=66 en-affil= kn-affil=Max-Planck-Institut fur Physik, Munchen, Germany affil-num=67 en-affil= kn-affil=Max-Planck-Institut fur Physik, Munchen, Germany affil-num=68 en-affil= kn-affil=Max-Planck-Institut fur Physik, Munchen, Germany affil-num=69 en-affil= kn-affil=Max-Planck-Institut fur Physik, Munchen, Germany affil-num=70 en-affil= kn-affil=Max-Planck-Institut fur Physik, Munchen, Germany affil-num=71 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=72 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=73 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=74 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=75 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=76 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=77 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=78 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=79 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=80 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=81 en-affil= kn-affil=NIKHEF, Amsterdam, The Netherlands affil-num=82 en-affil= kn-affil=Physics Department, Okayama University, Okayama, Japan affil-num=83 en-affil= kn-affil=Physics Department, Okayama University, Okayama, Japan affil-num=84 en-affil= kn-affil=University of Oslo, Oslo, Norway affil-num=85 en-affil= kn-affil=University of Oslo, Oslo, Norway affil-num=86 en-affil= kn-affil=University of Oslo, Oslo, Norway affil-num=87 en-affil= kn-affil=University of Oslo, Oslo, Norway affil-num=88 en-affil= kn-affil=University of Oslo, Oslo, Norway affil-num=89 en-affil= kn-affil=Department of Physics, Oxford University, Oxford, UK affil-num=90 en-affil= kn-affil=Department of Physics, Oxford University, Oxford, UK affil-num=91 en-affil= kn-affil=Department of Physics, Oxford University, Oxford, UK affil-num=92 en-affil= kn-affil=Academy of Sciences of the Czech Republic (ASCR), Prague, Czech Republic affil-num=93 en-affil= kn-affil=Academy of Sciences of the Czech Republic (ASCR), Prague, Czech Republic affil-num=94 en-affil= kn-affil=Academy of Sciences of the Czech Republic (ASCR), Prague, Czech Republic affil-num=95 en-affil= kn-affil=Charles University, Prague, Czech Republic affil-num=96 en-affil= kn-affil=Charles University, Prague, Czech Republic affil-num=97 en-affil= kn-affil=Charles University, Prague, Czech Republic affil-num=98 en-affil= kn-affil=Charles University, Prague, Czech Republic affil-num=99 en-affil= kn-affil=Charles University, Prague, Czech Republic affil-num=100 en-affil= kn-affil=Charles University, Prague, Czech Republic affil-num=101 en-affil= kn-affil=Charles University, Prague, Czech Republic affil-num=102 en-affil= kn-affil=Charles University, Prague, Czech Republic affil-num=103 en-affil= kn-affil=Czech Technical University, Prague, Czech Republic affil-num=104 en-affil= kn-affil=Czech Technical University, Prague, Czech Republic affil-num=105 en-affil= kn-affil=Czech Technical University, Prague, Czech Republic affil-num=106 en-affil= kn-affil=Czech Technical University, Prague, Czech Republic affil-num=107 en-affil= kn-affil=Czech Technical University, Prague, Czech Republic affil-num=108 en-affil= kn-affil=Czech Technical University, Prague, Czech Republic affil-num=109 en-affil= kn-affil=Czech Technical University, Prague, Czech Republic affil-num=110 en-affil= kn-affil=Czech Technical University, Prague, Czech Republic affil-num=111 en-affil= kn-affil=Czech Technical University, Prague, Czech Republic affil-num=112 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=113 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=114 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=115 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=116 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=117 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=118 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=119 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=120 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=121 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=122 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=123 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=124 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=125 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=126 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=127 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=128 en-affil= kn-affil=Rutherford Appleton Laboratory, Chilton, Didcot, UK affil-num=129 en-affil= kn-affil=Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, California, USA affil-num=130 en-affil= kn-affil=Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, California, USA affil-num=131 en-affil= kn-affil=Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, California, USA affil-num=132 en-affil= kn-affil=Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, California, USA affil-num=133 en-affil= kn-affil=Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, California, USA affil-num=134 en-affil= kn-affil=Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, California, USA affil-num=135 en-affil= kn-affil=Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, California, USA affil-num=136 en-affil= kn-affil=Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, California, USA affil-num=137 en-affil= kn-affil=Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, California, USA affil-num=138 en-affil= kn-affil=Institute of Physics, University of Tsukuba, Tsukuba, Japan affil-num=139 en-affil= kn-affil=Institute of Physics, University of Tsukuba, Tsukuba, Japan affil-num=140 en-affil= kn-affil=Institute of Physics, University of Tsukuba, Tsukuba, Japan affil-num=141 en-affil= kn-affil=Department of Radiation Sciences, Uppsala Universit, Uppsala, Sweden affil-num=142 en-affil= kn-affil=Department of Radiation Sciences, Uppsala Universit, Uppsala, Sweden affil-num=143 en-affil= kn-affil=Department of Radiation Sciences, Uppsala Universit, Uppsala, Sweden affil-num=144 en-affil= kn-affil=Department of Radiation Sciences, Uppsala Universit, Uppsala, Sweden affil-num=145 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=146 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=147 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=148 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=149 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=150 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=151 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=152 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=153 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=154 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=155 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=156 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=157 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain affil-num=158 en-affil= kn-affil=Instituto de Fisica Corpuscular (IFIC), Universidad de Valencia-CSIC, Valencia, Spain en-keyword=Front-end electronics kn-keyword=Front-end electronics en-keyword=Binary readout kn-keyword=Binary readout en-keyword=Silicon strip detectors kn-keyword=Silicon strip detectors en-keyword=Tracking detectors kn-keyword=Tracking detectors en-keyword=Radiation damage kn-keyword=Radiation damage END start-ver=1.4 cd-journal=joma no-vol=51 cd-vols= no-issue=3 article-no= start-page=252 end-page=256 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20049 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Assessment of MRI and dynamic contrast-enhanced MRI in the differential diagnosis of adenomatoid odontogenic tumor en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The radiographical differentiation of adenomatoid odontogenic tumor (AOT) from dentigerous cysts, calcifying odontogenic cysts, calcifying epithelial odontogenic tumors, odontogenic keratocysts, and amelobastomas is sometimes difficult. We attempted to differentiate AOT from other lesions similar to AOT in radiographic findings using MRI. The MRI features of AOT in our 3 cases included homogeneous low SI in the cystic portion and homogeneous intermediate SI in the solid portion on T1WI, homogeneous high SI in the cystic portion and intermediate to slightly high SI in the solid portion on T2WI, and enhancement of only the solid portion on CE-T1WI although non of the sequences included SI of calcifications. The contrast index curves in the 3 cases of AOT showed a gradual increase to 300 s, which signified a benign tumor. These MRI features were characteristic features of AOT and might be a basis for differentiating AOT from the above possible lesions in radiographic examinations.

en-copyright= kn-copyright= en-aut-name=AsaumiJun-ichi en-aut-sei=Asaumi en-aut-mei=Jun-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YanagiYoshinobu en-aut-sei=Yanagi en-aut-mei=Yoshinobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KonouchiHironobu en-aut-sei=Konouchi en-aut-mei=Hironobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HisatomiMiki en-aut-sei=Hisatomi en-aut-mei=Miki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MatsuzakiHidenobu en-aut-sei=Matsuzaki en-aut-mei=Hidenobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ShigeharaHiroshi en-aut-sei=Shigehara en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KishiKanji en-aut-sei=Kishi en-aut-mei=Kanji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Okayama University affil-num=7 en-affil= kn-affil=Okayama University en-keyword=AOT kn-keyword=AOT en-keyword=odontogenic tumor kn-keyword=odontogenic tumor en-keyword=odontogenic cyst kn-keyword=odontogenic cyst en-keyword=MRI kn-keyword=MRI en-keyword=DCE-MRI kn-keyword=DCE-MRI END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4 article-no= start-page=1111 end-page=1114 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=200704 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evidence for new beta 1-3 galactosyltransferase activity involved in biosynthesis of unusual N-glycan harboring T-antigen in Apis mellifera en-subtitle= kn-subtitle= en-abstract= kn-abstract=In a previous study (Y. Kimura et al., Biosci. Biotechnol Biochem., 70, 2583-2587, 2006), we found that new complex type N-glycans harboring Thomsen-Friedenreich antigen (Ga1 beta 1-3GalNAc) unit occur on royal jelly glycoproteins, suggesting the involvement of a new beta 1-3galactosyltransferase in the synthesis of the unusual complex type N-glycans. So far, such beta 1-3galactosyltransferase activity, which can transfer galactosyl residues with the beta 1-3 linkage to beta 1-4 GalNAc residues in N-glycan, has not been found among any eucaryotic cells. But using GalNAc(2)GlcNAc(2)Man(3)-GlcNAc(2)-PA as acceptor N-glycan, we detected the beta 1-3 galactosyltransferase activity in membrane fraction prepared from honeybee cephalic portions. This result indicates that honeybee expresses a unique beta 1-3 galactosyltransferase involved in biosynthesis of the unusual N-glycan containing a tumor related antigen in the hypopharyngeal gland. en-copyright= kn-copyright= en-aut-name=KimuraYoshinobu en-aut-sei=Kimura en-aut-mei=Yoshinobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SakamuraSho en-aut-sei=Sakamura en-aut-mei=Sho kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=UshijimaTakayuki en-aut-sei=Ushijima en-aut-mei=Takayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HamaYoichiro en-aut-sei=Hama en-aut-mei=Yoichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KajiuraHiroyuki en-aut-sei=Kajiura en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=FujiyamaKazuhito en-aut-sei=Fujiyama en-aut-mei=Kazuhito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=OkiharaKiyoshi en-aut-sei=Okihara en-aut-mei=Kiyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=HashimotoKen en-aut-sei=Hashimoto en-aut-mei=Ken kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=SugimotoHiroyuki en-aut-sei=Sugimoto en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=YamadaHideo en-aut-sei=Yamada en-aut-mei=Hideo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=Department of Biofunctional Chemistry, Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=Department of Biofunctional Chemistry, Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Department of Biofunctional Chemistry, Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University affil-num=4 en-affil= kn-affil=Department of Applied Biological Sciences, Faculty of Agriculture, Saga University affil-num=5 en-affil= kn-affil=The International Center for Biotechnology, Osaka University affil-num=6 en-affil= kn-affil=The International Center for Biotechnology, Osaka University affil-num=7 en-affil= kn-affil=Yamada Apiculture Center, Inc. affil-num=8 en-affil= kn-affil=Yamada Apiculture Center, Inc. affil-num=9 en-affil= kn-affil=Yamada Apiculture Center, Inc. affil-num=10 en-affil= kn-affil=Yamada Apiculture Center, Inc. en-keyword=royal jelly glycoprotein; N-glycan kn-keyword=royal jelly glycoprotein; N-glycan en-keyword=Thomsen-Friedenreich antigen (Gal beta 1-3GalNAc) kn-keyword=Thomsen-Friedenreich antigen (Gal beta 1-3GalNAc) en-keyword=beta 1-3 galactosyltransferase kn-keyword=beta 1-3 galactosyltransferase en-keyword=Apis mellifera kn-keyword=Apis mellifera END start-ver=1.4 cd-journal=joma no-vol=68 cd-vols= no-issue=11 article-no= start-page=1530 end-page=1536 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20076 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Serine racemases from barley, Hordeum vulgare L., and other plant species represent a distinct eukaryotic group: gene cloning and recombinant protein characterization en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Several D-amino acids have been identified in plants. However, the biosynthetic pathway to them is unclear. In this study, we cloned and sequenced a cDNA encoding a serine racemase from barley which contained an open reading frame encoding 337 amino acid residues. The deduced amino acid sequence showed significant identity to plant and mammalian serine racemases and contained conserved pyridoxal 5-phosphate (PLP)-binding lysine and PLP?interacting amino acid residues. The purified gene product catalyzed not only racemization of serine but also dehydration of serine to pyruvate. The enzyme requires PLP and divalent cations such as Ca2+, Mg2+, or Mn2+, but not ATP, whereas mammalian serine racemase activity is increased by ATP. In addition to the results regarding the effect of ATP on enzyme activity and the phylogenetic analysis of eukaryotic serine racemases, the antiserum against Arabidopsis serine racemase did not form a precipitate with barley and rice serine racemases. This suggests that plant serine racemases represent a distinct group in the eukaryotic serine racemase family and can be clustered into monocot and dicot types.

en-copyright= kn-copyright= en-aut-name=FujitaniYoshiyuki en-aut-sei=Fujitani en-aut-mei=Yoshiyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HoriuchiTerumi en-aut-sei=Horiuchi en-aut-mei=Terumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ItoKazutoshi en-aut-sei=Ito en-aut-mei=Kazutoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SugimotoManabu en-aut-sei=Sugimoto en-aut-mei=Manabu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Plant Bioengineering Research Laboratories, Sapporo Breweries Ltd. affil-num=4 en-affil= kn-affil=Okayama University en-keyword=Hordeum vulgare L. kn-keyword=Hordeum vulgare L. en-keyword=Oryza sativa kn-keyword=Oryza sativa en-keyword=Gramineae kn-keyword=Gramineae en-keyword=Pyridoxal 5-phosphate kn-keyword=Pyridoxal 5-phosphate en-keyword=Serine racemase kn-keyword=Serine racemase en-keyword=Serine dehydratase kn-keyword=Serine dehydratase en-keyword=d-Amino acid kn-keyword=d-Amino acid END start-ver=1.4 cd-journal=joma no-vol=279 cd-vols= no-issue=3 article-no= start-page=303 end-page=312 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080301 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Modulation of defense signal transduction by flagellin-induced WRKY41 transcription factor in Arabidopsis thaliana en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Flagellin, a component of the flagellar filament of Pseudomonas syringae pv. tabaci 6605 (Pta), induces hypersensitive reaction in its non-host Arabidopsis thaliana. We identified the WRKY41 gene, which belongs to a multigene family encoding WRKY plant-specific transcription factors, as one of the flagellin-inducible genes in A. thaliana. Expression of WRKY41 is induced by inoculation with the incompatible pathogen P. syringae pv. tomato DC3000 (Pto) possessing AvrRpt2 and the non-host pathogens Pta within 6-h after inoculation, but not by inoculation with the compatible Pto. Expression of WRKY41 was also induced by inoculation of A. thaliana with an hrp-type three secretion system (T3SS)-defective mutant of Pto, indicating that effectors produced by T3SS in the Pto wild-type suppress the activation of WRKY41. Arabidopsis overexpressing WRKY41 showed enhanced resistance to the Pto wild-type but increased susceptibility to Erwinia carotovora EC1. WRKY41-overexpressing Arabidopsis constitutively expresses the PR5 gene, but suppresses the methyl jasmonate-induced PDF1.2 gene expression. These results demonstrate that WRKY41 may be a key regulator in the cross talk of salicylic acid and jasmonic acid pathways.

en-copyright= kn-copyright= en-aut-name=HigashiKuniaki en-aut-sei=Higashi en-aut-mei=Kuniaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IshigaYasuhiro en-aut-sei=Ishiga en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=InagakiYoshishige en-aut-sei=Inagaki en-aut-mei=Yoshishige kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ToyodaKazuhiro en-aut-sei=Toyoda en-aut-mei=Kazuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ShiraishiTomonori en-aut-sei=Shiraishi en-aut-mei=Tomonori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=IchinoseYuki en-aut-sei=Ichinose en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=4 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=5 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=6 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University en-keyword=flagellin kn-keyword=flagellin en-keyword=flg22 kn-keyword=flg22 en-keyword=FLS2 kn-keyword=FLS2 en-keyword=MAMP signaling pathway kn-keyword=MAMP signaling pathway en-keyword=WRKY41 kn-keyword=WRKY41 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4 article-no= start-page=1086 end-page=1089 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=200704 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Three antinematodal diterpenes from Euphorbia kansui en-subtitle= kn-subtitle= en-abstract= kn-abstract=Three compounds, 20-O-acetyl-[3-O-(2'E,4'Z)-deca-dienoyl]-ingenol (1), 20-O-acetyl-[5-O-(2'E,4'Z)-decadienoyl]-ingenol (2) and 3-O-(2'E,4'Z)-decadienoylingenol (3), were isolated from Euphorbia kansui under the bioassay-guided method. Each compound showed the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 mu g/cotton ball. en-copyright= kn-copyright= en-aut-name=ShiJian-Xiao en-aut-sei=Shi en-aut-mei=Jian-Xiao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=LiZhi-Xuan en-aut-sei=Li en-aut-mei=Zhi-Xuan kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NitodaTeruhiko en-aut-sei=Nitoda en-aut-mei=Teruhiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=IzumiMinoru en-aut-sei=Izumi en-aut-mei=Minoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KanzakiHiroshi en-aut-sei=Kanzaki en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=BabaNaomichi en-aut-sei=Baba en-aut-mei=Naomichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KawazuKazuyoshi en-aut-sei=Kawazu en-aut-mei=Kazuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=NakajimaShuhei en-aut-sei=Nakajima en-aut-mei=Shuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=College of Life Science, Northwest University affil-num=2 en-affil= kn-affil=College of Life Science, Northwest University affil-num=3 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University affil-num=4 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University affil-num=5 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University affil-num=6 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University affil-num=7 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University affil-num=8 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Department of Biofunctional Chemistry, Laboratory of Applied Natural Products Chemistry, Okayama University en-keyword=antinematodal activity kn-keyword=antinematodal activity en-keyword=Bursaphelenchus xylophilus kn-keyword=Bursaphelenchus xylophilus en-keyword=diterpenoid kn-keyword=diterpenoid en-keyword=ingenane kn-keyword=ingenane en-keyword=Euphorbia kansui kn-keyword=Euphorbia kansui END start-ver=1.4 cd-journal=joma no-vol=272 cd-vols= no-issue=1 article-no= start-page=116 end-page=127 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20048 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Isolation of a transcriptionally active element of high copy number retrotransposons in sweetpotato genome en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Many plant retrotransposons have been characterized, but only three families (Tnt1, Tto1 and Tos17) have been demonstrated to be transpositionally competent. We followed a novel approach that enabled us to identify an active element of the Ty1-copia retrotransposon family with estimated 400 copies in the sweetpotato genome. DNA sequences of Ty1 -copia reverse transcriptase (RTase) from the sweetpotato genome were analyzed, and a group of retrotransposon copies probably formed by recent transposition events was further analyzed. 3’RACE on callus cDNA amplified transcripts containing long terminal repeats (LTR) of this group. The sequence -specific amplification polymorphism (S-SAP) patterns of the LTR sequence in the genomic DNA were compared between a normal plant and callus lines derived from it. A callus -specific S-SAP product was found into which the retrotransposon detected by the 3’RACE had been transposed apparently during cell culture. We conclude that our approach provides an effective way to identify active elements of retrotransposons with high copy numbers.

en-copyright= kn-copyright= en-aut-name=TaharaMakoto en-aut-sei=Tahara en-aut-mei=Makoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AokiTakahiro en-aut-sei=Aoki en-aut-mei=Takahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SuzukaShinya en-aut-sei=Suzuka en-aut-mei=Shinya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamashitaHiroki en-aut-sei=Yamashita en-aut-mei=Hiroki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TanakaMasaru en-aut-sei=Tanaka en-aut-mei=Masaru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MatsunagaSachi en-aut-sei=Matsunaga en-aut-mei=Sachi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KokumaiShuhei en-aut-sei=Kokumai en-aut-mei=Shuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=JEOL Limited affil-num=3 en-affil= kn-affil=SK Foods Company, Limited affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=National Agricultural Research Center affil-num=6 en-affil= kn-affil=Kabaya Foods Corporation affil-num=7 en-affil= kn-affil=Okayama University en-keyword=retrotransposon kn-keyword=retrotransposon en-keyword=Ipomoea batatas kn-keyword=Ipomoea batatas en-keyword=S-SAP kn-keyword=S-SAP en-keyword=transposition kn-keyword=transposition END start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue=1-2 article-no= start-page=59 end-page=66 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=200311 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Alternative methods to evaluate the protective ability of sunscreen against photo-genotoxicity en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Numerous epidemiological investigations show that sunlight is carcinogenic to humans and that the use of sunscreen may be effective in decreasing the risk of skin cancer. The biological activity of a sunscreen is evaluated by its ability to protect human skin from erythema as represented by a Sun Protection Factor (SPF). We propose that the sunscreen's protective effect against sunlight-induced genotoxicity, including mutation, should also be taken into account. In this study we examined the protective ability of sunscreens against natural sunlight and UV-induced genotoxicity in Drosophila somatic cells. We prepared three kinds of sunscreen samples, each with an SPF value of 20, 40 or 60 and compared their protective activities with commercial sunscreens. When a sunscreen of SPF 20, 40 or 60 was pasted on the plastic cover of a petri dish in which Drosophila larvae were exposed to the sun or UV lamps, genotoxicity decreased as the SPF of the sunscreen increased, relative to levels of genotoxicity observed in samples without sunscreen. However, the protective abilities of sunscreens were unexpectedly not so different from each other. To reveal the relationship between the protective activity of sunscreen and the wavelength of light with which larvae were irradiated through the sunscreen, we measured the transmittance of light through the petri dish cover on which the sunscreen was pasted. Effective protection was demonstrated by removing components of light whose wavelengths were below 315 nm. We suggest, that the measurement of anti-genotoxic activity and the determination of the wavelengths of light transmitted through the sunscreen should be an alternative method for evaluating the effectiveness of a sunscreen.

en-copyright= kn-copyright= en-aut-name=ToyoshimaMegumi en-aut-sei=Toyoshima en-aut-mei=Megumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HosodaKanako en-aut-sei=Hosoda en-aut-mei=Kanako kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HanamuraMiho en-aut-sei=Hanamura en-aut-mei=Miho kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OkamotoKeinosuke en-aut-sei=Okamoto en-aut-mei=Keinosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KobayashiHiroshi en-aut-sei=Kobayashi en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NegishiTomoe en-aut-sei=Negishi en-aut-mei=Tomoe kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Shiseido Research Center affil-num=6 en-affil= kn-affil=Okayama University en-keyword=sunscreen kn-keyword=sunscreen en-keyword=sunlight kn-keyword=sunlight en-keyword=UVB kn-keyword=UVB en-keyword=somatic cell mutation kn-keyword=somatic cell mutation en-keyword=genotoxicity kn-keyword=genotoxicity en-keyword=transmittance kn-keyword=transmittance en-keyword=Drosophila melanogaster kn-keyword=Drosophila melanogaster END start-ver=1.4 cd-journal=joma no-vol=143 cd-vols= no-issue=4 article-no= start-page=467 end-page=473 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080626 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Selenite Assimilation into Formate Dehydrogenase H Depends on Thioredoxin Reductase in Escherichia coli en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Escherichia coli growing under anaerobic conditions produce H-2 and CO2 by the enzymatic cleavage of formate that is produced from pyruvate at the end of glycolysis. Selenium is an integral part of formate dehydrogenase H (FDHH), which catalyses the first step in the formate hydrogen lyase (FHL) system. The genes of FHL system are transcribed only under anaerobic conditions, in the presence of a sigma(54)-dependent transcriptional activator Fh1A that binds formate as an effector molecule. Although the formate addition to the nutrient media has been an established procedure for inducing high FDHH activity, we have identified a low-salt nutrient medium containing <0.1% NaCl enabled constitutive, high expression of FDHH even without formate and D-glucose added to the medium. The novel conditions allowed us to study the effects of disrupting genes like trxB (thioredoxin reductase) or gor (glutathione reductase) on the production of FDHH activity and also reductive assimilation of selenite (SeO32-) into the selenoprotein. Despite the widely accepted hypothesis that selenite is reduced by glutathione reductase-dependent system, it was demonstrated that trxB gene was essential for FDHH production and for labelling the FDHH polypeptide with Se-75-selenite. Our present study reports for the first time the physiological involvement of thioredoxin reductase in the reductive assimilation of selenite in E. coli.

en-copyright= kn-copyright= en-aut-name=TakahataMuneaki en-aut-sei=Takahata en-aut-mei=Muneaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TamuraTakashi en-aut-sei=Tamura en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AbeKatsumasa en-aut-sei=Abe en-aut-mei=Katsumasa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MiharaHisaaki en-aut-sei=Mihara en-aut-mei=Hisaaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KurokawaSuguru en-aut-sei=Kurokawa en-aut-mei=Suguru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=YamamotoYoshihiro en-aut-sei=Yamamoto en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=NakanoRyuhei en-aut-sei=Nakano en-aut-mei=Ryuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=EsakiNobuyoshi en-aut-sei=Esaki en-aut-mei=Nobuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=InagakiKenji en-aut-sei=Inagaki en-aut-mei=Kenji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Laboratory of Molecular Microbial Science, Institute for Chemical Research, Kyoto University affil-num=4 en-affil= kn-affil=Laboratory of Molecular Microbial Science, Institute for Chemical Research, Kyoto University affil-num=5 en-affil= kn-affil=Laboratory of Molecular Microbial Science, Institute for Chemical Research, Kyoto University affil-num=6 en-affil= kn-affil=Department of Genetics, Hyogo College of Medicine affil-num=7 en-affil= kn-affil=Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=8 en-affil= kn-affil=Department of Genetics, Hyogo College of Medicine affil-num=9 en-affil= kn-affil=Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University en-keyword=formate dehydrogenase H kn-keyword=formate dehydrogenase H en-keyword=selenite assimilation kn-keyword=selenite assimilation en-keyword=thioredoxin reductase kn-keyword=thioredoxin reductase END start-ver=1.4 cd-journal=joma no-vol=579 cd-vols= no-issue=19 article-no= start-page=4069 end-page=4075 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma en-subtitle= kn-subtitle= en-abstract= kn-abstract=The EGF (epidermal growth factor) receptor-tyrosine kinase inhibitor ZD1839 (Gefitinib, 'Iressa') blocks the cell signaling pathways involved in cell proliferation, survival, and angiogenesis in various cancer cells. TNF-related death apoptosis inducing ligand (TRAIL) acts as an anticancer agent. We investigated the antitumor effects of ZD1839 alone or in combination with TRAIL against human esophageal squamous cell cancer (ESCC) lines. Although all ESCC cells expressed EGF receptor at a protein level, the effect of ZD1839 on cell growth did not correlate with the level of EGFR expression and phosphorylation of EGF receptor protein in ESCC lines. ZD1839 caused a dose-dependent growth arrest at G0?G1 phase associated with increased p27 expression. As TE8 cells are resistant to TRAIL, we tested whether ZD1839 combined with TRAIL induced apoptosis of TE8 cells via the inhibition of EGF receptor signaling by ZD1839. ZD1839 inhibited the phosphorylation of Akt, and enhanced TRAIL-induced apoptosis via activation of caspase-3 and caspase-9, and inactivation of Bcl-xL. Our results indicated that ZD1839 has anti-cancer properties against human esophageal cancer cells. ZD1839 also augmented the anti-cancer activity of TRAIL, even in TRAIL-resistant tumors. These results suggest that treatment with ZD1839 and TRAIL may have potential in the treatment of ESCC patients. en-copyright= kn-copyright= en-aut-name=TeraishiFuminori en-aut-sei=Teraishi en-aut-mei=Fuminori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KagawaShunsuke en-aut-sei=Kagawa en-aut-mei=Shunsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=WatanabeTakanori en-aut-sei=Watanabe en-aut-mei=Takanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TangoYasuhisa en-aut-sei=Tango en-aut-mei=Yasuhisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KawashimaTakeshi en-aut-sei=Kawashima en-aut-mei=Takeshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=UmeokaTatsuo en-aut-sei=Umeoka en-aut-mei=Tatsuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=NisizakiMasahiko en-aut-sei=Nisizaki en-aut-mei=Masahiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TanakaNoriaki en-aut-sei=Tanaka en-aut-mei=Noriaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=Division of Surgical Oncology, Department of Surgery, Okayama University Graduate School of Medicine and Dentistry affil-num=2 en-affil= kn-affil=Division of Surgical Oncology, Department of Surgery, Okayama University Graduate School of Medicine and Dentistry affil-num=3 en-affil= kn-affil=Division of Surgical Oncology, Department of Surgery, Okayama University Graduate School of Medicine and Dentistry affil-num=4 en-affil= kn-affil=Department of Surgery, Shiga University of Medical Science affil-num=5 en-affil= kn-affil=Division of Surgical Oncology, Department of Surgery, Okayama University Graduate School of Medicine and Dentistry affil-num=6 en-affil= kn-affil=Division of Surgical Oncology, Department of Surgery, Okayama University Graduate School of Medicine and Dentistry affil-num=7 en-affil= kn-affil=Division of Surgical Oncology, Department of Surgery, Okayama University Graduate School of Medicine and Dentistry affil-num=8 en-affil= kn-affil=Division of Surgical Oncology, Department of Surgery, Okayama University Graduate School of Medicine and Dentistry affil-num=9 en-affil= kn-affil=Division of Surgical Oncology, Department of Surgery, Okayama University Graduate School of Medicine and Dentistry en-keyword=epidermal growth factor receptor kn-keyword=epidermal growth factor receptor en-keyword=ZD1839 kn-keyword=ZD1839 en-keyword=akt kn-keyword=akt en-keyword=esophageal squamous cell cancer kn-keyword=esophageal squamous cell cancer en-keyword=tumor necrosis factor-related apoptosis inducing ligand kn-keyword=tumor necrosis factor-related apoptosis inducing ligand END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=3 article-no= start-page=826 end-page=829 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=200703 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Glucosylation of Sucrose Laurate with Cyclodextrin Glucanotransferase en-subtitle= kn-subtitle= en-abstract= kn-abstract=Sucrose monolauroyl esters were found to serve as substrates for cyclodextrin glucanotransferase (CGTase)-catalyzed transglucosidation reactions, affording new sucrose esters that have an additional 1-3 glucose residues on the pyranose ring of the sucrose moiety in the ester. en-copyright= kn-copyright= en-aut-name=OkadaKatsuhide en-aut-sei=Okada en-aut-mei=Katsuhide kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ZhaoHaisuo en-aut-sei=Zhao en-aut-mei=Haisuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IzumiMinoru en-aut-sei=Izumi en-aut-mei=Minoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NakajimaShuhei en-aut-sei=Nakajima en-aut-mei=Shuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=BabaNaomichi en-aut-sei=Baba en-aut-mei=Naomichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Research & Development Center, Hayashibara Biochemical Laboratories, Inc. affil-num=2 en-affil= kn-affil=Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University affil-num=4 en-affil= kn-affil=Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University affil-num=5 en-affil= kn-affil=Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University en-keyword=cyclodextrin glucanotransferase kn-keyword=cyclodextrin glucanotransferase en-keyword=CGTase kn-keyword=CGTase en-keyword=sucrose monolaurate kn-keyword=sucrose monolaurate en-keyword=surfactant kn-keyword=surfactant END start-ver=1.4 cd-journal=joma no-vol=279 cd-vols= no-issue=4 article-no= start-page=313 end-page=322 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=200804 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta gacA Delta gacS, were generated. These mutants produced smaller amounts of N-acyl homoserine lactones required for quorum sensing, had lost swarming motility, and had reduced expression of virulence-related hrp genes and the algT gene required for exopolysaccharide production. The ability of the mutants to cause disease symptoms in their host tobacco plant was remarkably reduced, while they retained the ability to induce hypersensitive reaction (HR) in the nonhost plants. These results indicated that the Gac two-component system of P. syringae pv. tabaci 6605 is indispensable for virulence on the host plant, but not for HR induction in the nonhost plants.

en-copyright= kn-copyright= en-aut-name=MarutaniMizuri en-aut-sei=Marutani en-aut-mei=Mizuri kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TaguchiFumiko en-aut-sei=Taguchi en-aut-mei=Fumiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OgawaYujiro en-aut-sei=Ogawa en-aut-mei=Yujiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HossainMijan Md. en-aut-sei=Hossain en-aut-mei=Mijan Md. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YoshishigeInagaki en-aut-sei=Yoshishige en-aut-mei=Inagaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ToyodaKazuhiro en-aut-sei=Toyoda en-aut-mei=Kazuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ShiraishiTomonori en-aut-sei=Shiraishi en-aut-mei=Tomonori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=IchinoseYuki en-aut-sei=Ichinose en-aut-mei=Yuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=Laboratory of Plant Pathology and Genetic Engineering, Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=Laboratory of Plant Pathology and Genetic Engineering, Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Laboratory of Plant Pathology and Genetic Engineering, Graduate School of Natural Science and Technology, Okayama University affil-num=4 en-affil= kn-affil=Laboratory of Plant Pathology and Genetic Engineering, Graduate School of Natural Science and Technology, Okayama University affil-num=5 en-affil= kn-affil=Laboratory of Plant Pathology and Genetic Engineering, Graduate School of Natural Science and Technology, Okayama University affil-num=6 en-affil= kn-affil=Laboratory of Plant Pathology and Genetic Engineering, Graduate School of Natural Science and Technology, Okayama University affil-num=7 en-affil= kn-affil=Laboratory of Plant Pathology and Genetic Engineering, Graduate School of Natural Science and Technology, Okayama University affil-num=8 en-affil= kn-affil=Laboratory of Plant Pathology and Genetic Engineering, Graduate School of Natural Science and Technology, Okayama University en-keyword=GacA kn-keyword=GacA en-keyword=GacS kn-keyword=GacS en-keyword=Pseudomonas syringae pv. tabaci kn-keyword=Pseudomonas syringae pv. tabaci en-keyword=quorum sensing kn-keyword=quorum sensing en-keyword=two-component system kn-keyword=two-component system END start-ver=1.4 cd-journal=joma no-vol=27 cd-vols= no-issue=24 article-no= start-page=8739 end-page=8747 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080706 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Drosophila blimp-1 is a transient transcriptional repressor that controls timing of the ecdysone-induced developmental pathway en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Regulatory mechanisms controlling the timing of developmental events are crucial for proper development to occur. ftz-fl is expressed in a temporally regulated manner following pulses of ecdysteroid and this precise expression is necessary for the development of Drosophila melanogaster. To understand how insect hormone ecdysteroids regulate the timing of FTZ-F1 expression, we purified a DNA binding regulator of ftz-fl. Mass spectroscopy analysis revealed this protein to be a fly homolog of mammalian B lymphocyte-induced maturation protein 1 (Blimp-1). Drosophila Blimp-1 (dBlimp-1) is induced directly by 20-hydroxyecdysone, and its product exists during high-ecdysteroid periods and turns over rapidly. Forced expression of dBlimp-1 and RNA interference analysis indicate that dBlimp-1 acts as a repressor and controls the timing of FTZ-F1 expression. Furthermore, its prolonged expression results in delay of pupation timing. These results suggest that the transient transcriptional repressor dBlimp-1 is important for determining developmental timing in the ecdysone-induced pathway.

en-copyright= kn-copyright= en-aut-name=AgawaYasuo en-aut-sei=Agawa en-aut-mei=Yasuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SarhanMoustafa en-aut-sei=Sarhan en-aut-mei=Moustafa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KageyamaYuji en-aut-sei=Kageyama en-aut-mei=Yuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AkagiKazutaka en-aut-sei=Akagi en-aut-mei=Kazutaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TakaiMasayoshi en-aut-sei=Takai en-aut-mei=Masayoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HashiyamaKazuya en-aut-sei=Hashiyama en-aut-mei=Kazuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=WadaTadashi en-aut-sei=Wada en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=HandaHiroshi en-aut-sei=Handa en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=IwamatsuAkihiro en-aut-sei=Iwamatsu en-aut-mei=Akihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=HiroseSusumu en-aut-sei=Hirose en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=UedaHitoshi en-aut-sei=Ueda en-aut-mei=Hitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=Department of Developmental Genetics, National Institute of Genetics and Department of Genetics, The Graduate University for Advanced Studies affil-num=2 en-affil= kn-affil=The Graduate School of Natural Science and Technology and Department of Biology, Faculty of Science, Okayama University affil-num=3 en-affil= kn-affil=Department of Developmental Genetics, National Institute of Genetics and Department of Genetics, The Graduate University for Advanced Studies affil-num=4 en-affil= kn-affil=The Graduate School of Natural Science and Technology and Department of Biology, Faculty of Science, Okayama University affil-num=5 en-affil= kn-affil=The Graduate School of Natural Science and Technology and Department of Biology, Faculty of Science, Okayama University affil-num=6 en-affil= kn-affil=Department of Developmental Genetics, National Institute of Genetics and Department of Genetics, The Graduate University for Advanced Studies affil-num=7 en-affil= kn-affil=Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology affil-num=8 en-affil= kn-affil=Integrated Research Institute, Tokyo Institute of Technology affil-num=9 en-affil= kn-affil=Protein Research Network, Inc. affil-num=10 en-affil= kn-affil=Department of Developmental Genetics, National Institute of Genetics and Department of Genetics, The Graduate University for Advanced Studies affil-num=11 en-affil= kn-affil=The Graduate School of Natural Science and Technology and Department of Biology, Faculty of Science, Okayama University en-keyword=SEQUENTIAL GENE ACTIVATION kn-keyword=SEQUENTIAL GENE ACTIVATION en-keyword=MATURATION PROTEIN-1 BLIMP-1 kn-keyword=MATURATION PROTEIN-1 BLIMP-1 en-keyword=STEROID-RECEPTOR SUPERFAMILY kn-keyword=STEROID-RECEPTOR SUPERFAMILY en-keyword=POLYTENE CHROMOSOMES kn-keyword=POLYTENE CHROMOSOMES en-keyword=SALIVARY-GLAND kn-keyword=SALIVARY-GLAND en-keyword=FUSHI-TARAZU kn-keyword=FUSHI-TARAZU en-keyword=EMBRYONIC-DEVELOPMENT kn-keyword=EMBRYONIC-DEVELOPMENT en-keyword=MOLECULAR-MECHANISM kn-keyword=MOLECULAR-MECHANISM en-keyword=TEMPORAL REGULATION kn-keyword=TEMPORAL REGULATION en-keyword=STAGE SPECIFICITY kn-keyword=STAGE SPECIFICITY END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=4 article-no= start-page=1078 end-page=1082 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=200704 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Synthesis of lipid derivatives of pyrrole polyamide and their biological activity en-subtitle= kn-subtitle= en-abstract= kn-abstract=Novel fatty acyl and phospholipid derivatives of pyrrole polyamide were synthesized. Their cytotoxicity against a cancer cell line of MT-4 cells and those infected by human immunodeficiency virus (HIV) was examined. Although no anti-HIV activity was found, their cytotoxicitty against the cancer cells was significantly enhanced by introducing a lipophilic group into the pyrrole polyamide. en-copyright= kn-copyright= en-aut-name=YamamotoMasahiko en-aut-sei=Yamamoto en-aut-mei=Masahiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ZhuChangjin en-aut-sei=Zhu en-aut-mei=Changjin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YiLui en-aut-sei=Yi en-aut-mei=Lui kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=RongZheng en-aut-sei=Rong en-aut-mei=Zheng kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MiuraYoshie en-aut-sei=Miura en-aut-mei=Yoshie kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=IzumiMinoru en-aut-sei=Izumi en-aut-mei=Minoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=NakajimaShuhei en-aut-sei=Nakajima en-aut-mei=Shuhei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TanamotoKen-ichi en-aut-sei=Tanamoto en-aut-mei=Ken-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=ShimizuSakayu en-aut-sei=Shimizu en-aut-mei=Sakayu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=BabaNaomichi en-aut-sei=Baba en-aut-mei=Naomichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=School of Chemical Engineering & Environment, Beijing Institute of Technology affil-num=3 en-affil= kn-affil=School of Chemical Engineering & Environment, Beijing Institute of Technology affil-num=4 en-affil= kn-affil=School of Chemical Engineering & Environment, Beijing Institute of Technology affil-num=5 en-affil= kn-affil=Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=6 en-affil= kn-affil=Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=7 en-affil= kn-affil=Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=8 en-affil= kn-affil=National Institute of Health Sciences, Division of Food Additives affil-num=9 en-affil= kn-affil=Department of Applied Bioscience, Graduate School of Agriculture, Kyoto University affil-num=10 en-affil= kn-affil=Department of Biofunctional Chemistry, Graduate School of Natural Science and Technology, Okayama University en-keyword=pyrrole polyamide kn-keyword=pyrrole polyamide en-keyword=lipid kn-keyword=lipid en-keyword=phospholipid kn-keyword=phospholipid en-keyword=cancer cell kn-keyword=cancer cell en-keyword=human immunodeficiency virus (HIV)-II kn-keyword=human immunodeficiency virus (HIV)-II END start-ver=1.4 cd-journal=joma no-vol=25 cd-vols= no-issue=18 article-no= start-page=4175 end-page=4186 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060920 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Secretion of L-glutamate from osteoclasts through transcytosis en-subtitle= kn-subtitle= en-abstract= kn-abstract=Osteoclasts are involved in the catabolism of the bone matrix and eliminate the resulting degradation products through transcytosis, but the molecular mechanism and regulation of transcytosis remain poorly understood. Upon differentiation, osteoclasts express vesicular glutamate transporter 1 (VGLUT1), which is essential for vesicular storage and subsequent exocytosis of glutamate in neurons. VGLUT1 is localized in transcytotic vesicles and accumulates L-glutamate. Osteoclasts secrete L-glutamate and the bone degradation products upon stimulation with KCl or ATP in a Ca2+-dependent manner. KCl- and ATP-dependent secretion of L-glutamate was absent in osteoclasts prepared from VGLUT1-/- knockout mice. Osteoclasts express mGluR8, a class III metabotropic glutamate receptor. Its stimulation by a specific agonist inhibits secretion of L-glutamate and bone degradation products, whereas its suppression by a specific antagonist stimulates bone resorption. Finally, it was found that VGLUT1-/- mice develop osteoporosis. Thus, in bone-resorbing osteoclasts, L-glutamate and bone degradation products are secreted through transcytosis and the released L-glutamate is involved in autoregulation of transcytosis. Glutamate signaling may play an important role in the bone homeostasis. en-copyright= kn-copyright= en-aut-name=MorimotoRiyo en-aut-sei=Morimoto en-aut-mei=Riyo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=UeharaShunsuke en-aut-sei=Uehara en-aut-mei=Shunsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YatsushiroShouki en-aut-sei=Yatsushiro en-aut-mei=Shouki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=JugeNarinobu en-aut-sei=Juge en-aut-mei=Narinobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=HuaZhaolin en-aut-sei=Hua en-aut-mei=Zhaolin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SenohShigenori en-aut-sei=Senoh en-aut-mei=Shigenori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=EchigoNoriko en-aut-sei=Echigo en-aut-mei=Noriko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=HayashiMitsuko en-aut-sei=Hayashi en-aut-mei=Mitsuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=MizoguchiToshihide en-aut-sei=Mizoguchi en-aut-mei=Toshihide kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=NinomiyaTadashi en-aut-sei=Ninomiya en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=UdagawaNobuyuki en-aut-sei=Udagawa en-aut-mei=Nobuyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=OmoteHiroshi en-aut-sei=Omote en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=YamamotoAkitsugu en-aut-sei=Yamamoto en-aut-mei=Akitsugu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=EdwardsRobert H en-aut-sei=Edwards en-aut-mei=Robert H kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=MoriyamaYoshinori en-aut-sei=Moriyama en-aut-mei=Yoshinori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= affil-num=1 en-affil= kn-affil=Laboratory of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=2 en-affil= kn-affil=Laboratory of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=3 en-affil= kn-affil=Laboratory of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=4 en-affil= kn-affil=Laboratory of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=5 en-affil= kn-affil=Departments of Neurology and Physiology, Graduate Programs in Neuroscience and Cell Biology, University of California San Francisco School of Medicine affil-num=6 en-affil= kn-affil=Laboratory of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=7 en-affil= kn-affil=Laboratory of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=8 en-affil= kn-affil=Laboratory of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=9 en-affil= kn-affil=Institute for Oral Science, Matsumoto Dental University affil-num=10 en-affil= kn-affil=Institute for Oral Science, Matsumoto Dental University affil-num=11 en-affil= kn-affil=Department of Biochemistry, Matsumoto Dental University affil-num=12 en-affil= kn-affil=Laboratory of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=13 en-affil= kn-affil=Department of Cell Biology, Nagahama Institute of Bioscience and Technology affil-num=14 en-affil= kn-affil=Departments of Neurology and Physiology, Graduate Programs in Neuroscience and Cell Biology, University of California San Francisco School of Medicine affil-num=15 en-affil= kn-affil=Laboratory of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences en-keyword=osteoclast kn-keyword=osteoclast en-keyword=vesicular glutamate transporter kn-keyword=vesicular glutamate transporter en-keyword=transcytosis kn-keyword=transcytosis en-keyword=bone resorption kn-keyword=bone resorption END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=50 article-no= start-page=17923 end-page=17928 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=A human transporter protein that mediates the final excretion step for toxic organic cations en-subtitle= kn-subtitle= en-abstract= kn-abstract=

In mammals, toxic electrolytes of endogenous and exogenous origin are excreted through the urine and bile. Before excretion, these compounds cross numerous cellular membranes in a transporter-mediated manner. However, the protein transporters involved in the final excretion step are poorly understood. Here, we show that MATE1, a human and mouse orthologue of the multidrug and toxin extrusion (MATE) family conferring multidrug resistance on bacteria, is primarily expressed in the kidney and liver, where it is localized to the luminal membranes of the urinary tubules and bile canaliculi. When expressed in HEK293 cells, MATE1 mediates H+-coupled electroneutral exchange of tetraethylammonium (TEA) and 1-methyl-4-phenylpyridinium (MPP). Its substrate specificity is similar to those of renal and hepatic H+-coupled organic cations (OCs) export. Thus, MATE1 appears to be the long searched for polyspecific OC exporter that directly transports toxic OCs into urine and bile.

en-copyright= kn-copyright= en-aut-name=OtsukaMasato en-aut-sei=Otsuka en-aut-mei=Masato kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MatsumotoTakuya en-aut-sei=Matsumoto en-aut-mei=Takuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MorimotoRiyo en-aut-sei=Morimoto en-aut-mei=Riyo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AriokaShigeo en-aut-sei=Arioka en-aut-mei=Shigeo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OmoteHiroshi en-aut-sei=Omote en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MoriyamaYoshinori en-aut-sei=Moriyama en-aut-mei=Yoshinori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Okayama University en-keyword=MATE kn-keyword=MATE en-keyword=multidrug export kn-keyword=multidrug export en-keyword=excretion kn-keyword=excretion en-keyword=toxin kn-keyword=toxin en-keyword=urinary tubule kn-keyword=urinary tubule en-keyword=bile canaliculus kn-keyword=bile canaliculus en-keyword=organic cation kn-keyword=organic cation en-keyword=H+/cation antiport. kn-keyword=H+/cation antiport. END start-ver=1.4 cd-journal=joma no-vol=41 cd-vols= no-issue=3 article-no= start-page=134 end-page=139 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=200802 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Association of elevated plasma B-type natriuretic peptide levels with paroxysmal atrial fibrillation in patients with nonobstructive hypertrophic cardiomyopathy en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Objectives: To investigate the relationship between the plasma B-type natriuretic peptide (BNP) level and the occurrence of atrial fibrillation (AF) in nonobstructive hypertrophic cardiomyopathy (HCM) patients.
Methods: Patients (n=97) were classified into chronic AF (CAF; n=14), paroxysmal AF (PAF; n=18) and normal sinus rhythm (NSR; n=65) groups. The plasma BNP values were analyzed with logarithmic transformation.
Results: The PAF group showed significantly higher plasma BNP levels than the NSR group [mean (range; -1 SD and +1 SD); 248.3 (143.5, 429.5) vs. 78.2 (27.9, 218.8 ng/L), p<0.0001]. The CAF group also showed significantly higher plasma BNP levels than the NSR group [291.1 (161.4, 524.8 ng/L), p<0.0001]. Multivariate analysis with other clinical factors selected association of PAF as one of the factors that increased the plasma BNP level.
Conclusions: The present study indicated that plasma BNP level is clinically useful for identification of nonobstructive HCM patients who have a risk of PAF.

en-copyright= kn-copyright= en-aut-name=MatsuuraHiroko en-aut-sei=Matsuura en-aut-mei=Hiroko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MurakamiTakashi en-aut-sei=Murakami en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HinaKazuyoshi en-aut-sei=Hina en-aut-mei=Kazuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamamotoKeizo en-aut-sei=Yamamoto en-aut-mei=Keizo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KawamuraHiroshi en-aut-sei=Kawamura en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=SogoTaiji en-aut-sei=Sogo en-aut-mei=Taiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ShinohataRyoko en-aut-sei=Shinohata en-aut-mei=Ryoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=UsuiShinichi en-aut-sei=Usui en-aut-mei=Shinichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=NinomiyaYoshifumi en-aut-sei=Ninomiya en-aut-mei=Yoshifumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=KusachiShozo en-aut-sei=Kusachi en-aut-mei=Shozo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=Department of Medicine and Medical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=2 en-affil= kn-affil=Department of Cardiology, Cardiovascular Center, Sakakibara Hospital affil-num=3 en-affil= kn-affil=Department of Cardiology, Cardiovascular Center, Sakakibara Hospital affil-num=4 en-affil= kn-affil=Department of Cardiology, Cardiovascular Center, Sakakibara Hospital affil-num=5 en-affil= kn-affil=Department of Cardiology, Cardiovascular Center, Sakakibara Hospital affil-num=6 en-affil= kn-affil=Department of Cardiovascular Medicine, Takamatsu Red Cross Hospital affil-num=7 en-affil= kn-affil=Department of Medical Technology, Okayama University Graduate School of Health Sciences affil-num=8 en-affil= kn-affil=Department of Medical Technology, Okayama University Graduate School of Health Sciences affil-num=9 en-affil= kn-affil=Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=10 en-affil= kn-affil=Department of Medical Technology, Okayama University Graduate School of Health Sciences en-keyword=clinical study kn-keyword=clinical study en-keyword=cardiomyopathy kn-keyword=cardiomyopathy en-keyword=tachyarrhythmia kn-keyword=tachyarrhythmia en-keyword=enzyme immunoassay kn-keyword=enzyme immunoassay en-keyword=peptide kn-keyword=peptide en-keyword=sensitivity and specificity kn-keyword=sensitivity and specificity END start-ver=1.4 cd-journal=joma no-vol=126 cd-vols= no-issue=3 article-no= start-page=427 end-page=429 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080622 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Expression of monocyte chemoattractant protein-1 in idiopathic dilated cardiomyopathy en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Immunological factors have been involved in the pathogenesis of dilated cardiomyopathy (DCM). The cytotoxic action of macrophages is one of the main factors causing cardiac myocyte damage. Monocyte chemoattractant protein-1 (MCP-1) is a major signal for the accumulation of monocytes/macrophages. We examined whether MCP-1 was expressed in the myocardium of DCM patients and whether the expression level was correlated with the degree of impairment of cardiac function. The expression of MCP-1 in the myocardium was determined by immunohistochemistry in endomyocardial biopsy samples from 13 patients. The expression of MCP-1 was found in all myocardial samples from DCM patients but not in those from control subjects. Positive staining for MCP-1 was distinct in cardiac myocytes, interstitium and infiltrating cells. Semi-quantitative analysis revealed that the expression of MCP-1 was inversely correlated with left ventricular ejection fraction. In conclusion, the expression level of MCP-1 in the myocardium was correlated with the degree of impairment of cardiac function in patients with DCM.

en-copyright= kn-copyright= en-aut-name=KobayashiMakoto en-aut-sei=Kobayashi en-aut-mei=Makoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NakamuraKazufumi en-aut-sei=Nakamura en-aut-mei=Kazufumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KusanoKengo Fukushima en-aut-sei=Kusano en-aut-mei=Kengo Fukushima kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NakamuraYoichi en-aut-sei=Nakamura en-aut-mei=Yoichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=Ohta-OgoKeiko en-aut-sei=Ohta-Ogo en-aut-mei=Keiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NagaseSatoshi en-aut-sei=Nagase en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=SakuragiSatoru en-aut-sei=Sakuragi en-aut-mei=Satoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=OheTohru en-aut-sei=Ohe en-aut-mei=Tohru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=2 en-affil= kn-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=3 en-affil= kn-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=4 en-affil= kn-affil=aDepartment of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=5 en-affil= kn-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=6 en-affil= kn-affil=aDepartment of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=7 en-affil= kn-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=8 en-affil= kn-affil=Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences en-keyword=cardiomyopathy kn-keyword=cardiomyopathy en-keyword=immunohistochemistry kn-keyword=immunohistochemistry en-keyword=monocyte kn-keyword=monocyte END start-ver=1.4 cd-journal=joma no-vol=66 cd-vols= no-issue=5 article-no= start-page=648 end-page=652 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=200805 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Radioactivity and radon emanation fraction of the granites sampled at Misasa and Badgastein en-subtitle= kn-subtitle= en-abstract= kn-abstract=The chemical composition was analyzed and the radioactivity, radon exhalation rate and emanation fraction were measured to investigate the characteristics of the granites sampled at Misasa and Badgastein, world famous for radon therapy. The Misasa granite was probably composed of quartz, albite and microcline. The Badgastein granite was probably composed of quartz and muscovite. The radon exhalation rates and emanation fractions of the Misasa granite were much higher than those of the Badgastein granite, regardless of the Ra-226 activity concentrations. en-copyright= kn-copyright= en-aut-name=SakodaAkihiro en-aut-sei=Sakoda en-aut-mei=Akihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HanamotoKatsumi en-aut-sei=Hanamoto en-aut-mei=Katsumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IshimoriYu en-aut-sei=Ishimori en-aut-mei=Yu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NagamatsuTomohiro en-aut-sei=Nagamatsu en-aut-mei=Tomohiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YamaokaKiyonori en-aut-sei=Yamaoka en-aut-mei=Kiyonori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Graduate School of Health Sciences, Okayama University affil-num=2 en-affil= kn-affil=Graduate School of Health Sciences, Okayama University affil-num=3 en-affil= kn-affil=Ningyo-toge Environmental Engineering Center, Japan Atomic Energy Agency affil-num=4 en-affil= kn-affil=Graduate School of Health Sciences, Okayama University affil-num=5 en-affil= kn-affil=Graduate School of Health Sciences, Okayama University en-keyword=radioactivity kn-keyword=radioactivity en-keyword=radon emanation fraction kn-keyword=radon emanation fraction en-keyword=granite kn-keyword=granite en-keyword=Misasa kn-keyword=Misasa en-keyword=Badgastein kn-keyword=Badgastein END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=6 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200512 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Vortex structure in spinor f=2 bose-einstein condensates en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Extended Gross-Pitaevskii equations for the rotating F=2 condensate in a harmonic trap are solved both numerically and variationally using trial functions for each component of the wave function. Axially symmetric vortex solutions are analyzed and energies of polar and cyclic states are calculated. The equilibrium transitions between different phases with changing of the magnetization are studied. We show that at high magnetization the ground state of the system is determined by interaction in "density" channel, and at low magnetization spin interactions play a dominant role. Although there are five hyperfine states, all the particles are always condensed in one, two, or three states. Two interesting types of vortex structures are also discussed.

en-copyright= kn-copyright= en-aut-name=PogosovW V en-aut-sei=Pogosov en-aut-mei=W V kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KawateR en-aut-sei=Kawate en-aut-mei=R kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MizushimaT en-aut-sei=Mizushima en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MachidaK en-aut-sei=Machida en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=vortices kn-keyword=vortices END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=1 end-page=4 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20072 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Theory of tunneling spectroscopy in the larkin-ovchinnikov state en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We present a theory of tunneling spectroscopy for normal metal/Larkin-Ovchinnikov state junctions in which the spatial periodic modulation in the pair potential amplitude is taken into account. The tunneling spectra show the characteristic line shapes reflecting the minigap structures under the periodic pair potentials depending on the boundary condition of the pair potentials at the junction interface. These features are qualitatively different from the tunneling spectra of the Fulde-Ferrell state. We propose an experimental setup which identifies the superconducting state of CeCoIn5.

en-copyright= kn-copyright= en-aut-name=TanakaYukio en-aut-sei=Tanaka en-aut-mei=Yukio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AsanoYasuhiro en-aut-sei=Asano en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IchikawaMasanori en-aut-sei=Ichikawa en-aut-mei=Masanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KashiwayaSatoshi en-aut-sei=Kashiwaya en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Nagoya University affil-num=2 en-affil= kn-affil=Japan Science and Technology Corporation affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=NeRI of National Institute of Advanced Industrial Science and Technology END start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue=1 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20061 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Sound velocity and multibranch bogoliubov spectrum of an elongated fermi superfluid in the BEC-BCS crossover en-subtitle= kn-subtitle= en-abstract= kn-abstract=We study properties of excited states of an elongated Fermi superfluid along the Bose-Einstein-condensate-BCS crossover including the unitarity limit. Analytic expressions for the sound velocity in an inhomogeneous as well as homogeneous Fermi superfluid along the crossover are obtained on the basis of the hydrodynamic theory. The complete excitation spectrum of axial quasiparticles with various discrete radial nodes is presented. We discuss the feasibility of measuring the sound velocity and the multibranch Bogoliubov spectrum experimentally. en-copyright= kn-copyright= en-aut-name=GhoshTarun Kanti en-aut-sei=Ghosh en-aut-mei=Tarun Kanti kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MachidaKazushige en-aut-sei=Machida en-aut-mei=Kazushige kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University en-keyword=bose-einstein condensate kn-keyword=bose-einstein condensate en-keyword=gas kn-keyword=gas en-keyword=propagation kn-keyword=propagation en-keyword=resonance kn-keyword=resonance END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=5 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200511 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Multibranch Bogoliubov-Bloch spectrum of a cigar-shaped Bose condensate in an optical lattice en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We study properties of excited states of an array of weakly coupled quasi-two-dimensional Bose condensates by using the hydrodynamic theory. The spectrum of the axial excited states strongly depends on the coupling among the various discrete radial modes in a given symmetry. By including mode coupling within a given symmetry, the complete excitation spectrum of axial quasiparticles with various discrete radial nodes are presented. A single parameter which determines the strength of the mode coupling is identified. The excitation spectrum in the zero angular momentum sector can be observed by using the Bragg scattering experiments.

en-copyright= kn-copyright= en-aut-name=GhoshTarun Kanti en-aut-sei=Ghosh en-aut-mei=Tarun Kanti kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MachidaK. en-aut-sei=Machida en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University en-keyword=einstein kn-keyword=einstein en-keyword=condensate kn-keyword=condensate en-keyword=superfluid kn-keyword=superfluid en-keyword=arrays kn-keyword=arrays en-keyword=atoms kn-keyword=atoms en-keyword=wave kn-keyword=wave en-keyword=gas kn-keyword=gas END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page=1 end-page=4 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20071 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Observation of a superconducting gap in boron-doped diamond by laser-excited photoemission spectroscopy en-subtitle= kn-subtitle= en-abstract= kn-abstract=

<p>We investigate the temperature (T)-dependent low-energy electronic structure of a boron-doped diamond thin film using ultrahigh resolution laser-excited photoemission spectroscopy. We observe a clear shift of the leading edge below T=11 K, indicative of a superconducting gap opening (Delta~0.78 meV at T=4.5 K). The gap feature is significantly broad and a well-defined quasiparticle peak is lacking even at the lowest temperature of measurement (=4.5 K). We discuss our results in terms of disorder effects on the normal state transport and superconductivity in this system.</p>

en-copyright= kn-copyright= en-aut-name=IshizakaK. en-aut-sei=Ishizaka en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=EguchiR. en-aut-sei=Eguchi en-aut-mei=R. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TsudaS. en-aut-sei=Tsuda en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YokotaT. en-aut-sei=Yokota en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ChainaniA. en-aut-sei=Chainani en-aut-mei=A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KissT. en-aut-sei=Kiss en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ShimojimaT. en-aut-sei=Shimojima en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TogashiT. en-aut-sei=Togashi en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=WatanabeS. en-aut-sei=Watanabe en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=ChenC. T. en-aut-sei=Chen en-aut-mei=C. T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=ZhangC. Q. en-aut-sei=Zhang en-aut-mei=C. Q. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=TakanoY. en-aut-sei=Takano en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=NagaoM. en-aut-sei=Nagao en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=SakuguchiI. en-aut-sei=Sakuguchi en-aut-mei=I. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=TakenouchiT. en-aut-sei=Takenouchi en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=ShinS. en-aut-sei=Shin en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= affil-num=1 en-affil= kn-affil=University of Tokyo affil-num=2 en-affil= kn-affil=The Institute of Physical and Chemical Research (RIKEN) affil-num=3 en-affil= kn-affil=University of Tokyo affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=The Institute of Physical and Chemical Research (RIKEN) affil-num=6 en-affil= kn-affil=The Institute of Physical and Chemical Research (RIKEN) affil-num=7 en-affil= kn-affil=University of Tokyo affil-num=8 en-affil= kn-affil=The Institute of Physical and Chemical Research (RIKEN) affil-num=9 en-affil= kn-affil=University of Tokyo affil-num=10 en-affil= kn-affil=Chinese Academy of Science affil-num=11 en-affil= kn-affil=Chinese Academy of Science affil-num=12 en-affil= kn-affil=National Institute for Materials Science affil-num=13 en-affil= kn-affil=National Institute for Materials Science affil-num=14 en-affil= kn-affil=National Institute for Materials Science affil-num=15 en-affil= kn-affil=Waseda University affil-num=16 en-affil= kn-affil=University of Tokyo END start-ver=1.4 cd-journal=joma no-vol=74 cd-vols= no-issue=2 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20068 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Cyclic phase in f=2 spinor condensate:long-range order, kinks, and roughening transition en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We study the effect of thermal fluctuations on homogeneous infinite Bose-Einstein condensate with spin F=2 in the cyclic state, when atoms occupy three hyperfine states with m(F)=0,+/- 2. We use both the approach of small-amplitude oscillations and mapping of our model on the sine-Gordon model. We show that thermal fluctuations lead to the existence of the rough phase in one- and two-dimensional systems, when the presence of kinks is favorable. The structure and energy of a single kink are found. We also discuss the effect of thermal fluctuations on spin degrees of freedom in F=1 condensate.

en-copyright= kn-copyright= en-aut-name=PogosovW V en-aut-sei=Pogosov en-aut-mei=W V kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MachidaK en-aut-sei=Machida en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University en-keyword=bose-einstein condensate kn-keyword=bose-einstein condensate en-keyword=dynamics kn-keyword=dynamics en-keyword=gases kn-keyword=gases END start-ver=1.4 cd-journal=joma no-vol=74 cd-vols= no-issue=2 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20068 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Thermal fluctuations of vortex clusters in quasi-two-dimensional bose-einstein condensates en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We study the thermal fluctuations of vortex positions in small vortex clusters in a harmonically trapped rotating Bose-Einstein condensate. It is shown that the order-disorder transition of two-shell clusters occurs via the decoupling of shells with respect to each other. The corresponding "melting" temperature depends strongly on the commensurability between numbers of vortices in shells. We show that melting can be achieved at experimentally attainable parameters and very low temperatures. Also studied is the effect of thermal fluctuations on vortices in an anisotropic trap with small quadrupole deformation. We show that thermal fluctuations lead to the decoupling of a vortex cluster from the pinning potential produced by this deformation. The decoupling temperatures are estimated and strong commensurability effects are revealed.

en-copyright= kn-copyright= en-aut-name=PogosovW V en-aut-sei=Pogosov en-aut-mei=W V kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MachidaK en-aut-sei=Machida en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University en-keyword=scissors mode kn-keyword=scissors mode en-keyword=gas kn-keyword=gas en-keyword=superfluidity kn-keyword=superfluidity en-keyword=transition kn-keyword=transition en-keyword=stability kn-keyword=stability en-keyword=phase kn-keyword=phase END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=8 article-no= start-page=1343 end-page=1349 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20068 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Using assessment of higher brain functions of children with GJB2-associated deafness and cochlear implants as a procedure to evaluate language development en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Objective: While investigators have reported that patients with GJB2-associated deafness and cochlear implants have preferable language development, the mechanisms of this phenomenon remains unknown. The goat of the present study was to assess higher brain functions of patients with GJB2-retated and GJB2-unrelated deafness as a method of evaluating language development.
Methods: Eight children with cochlear implants were subjected to genetic testing for GJB2 and underwent the Raven colored progressive matrices test, Rey's auditory verbal learning test, Rey's complex figure test, the standardized Language test for aphasia, the picture vocabulary test, and the standardized comprehension test for abstract words.
Results:Three children were diagnosed with GJB2-related deafness, and five children were diagnosed with GJB2-unrelated deafness. All three GJB2-related cases demonstrated normal range higher brain functions and fair language development. By contrast, one GJB2-unrelated case showed a semantic disorder, another demonstrated a visual cognitive disorder with dyslexia, and another had attention deficit-hyperactivity disorder.
Conclusions:Children with GJB2-unrelated deafness showed a high frequency of heterogeneous disorders that can affect proper language development. This difference between children with GJB2-retated and GJB2-unrelated deafness may account for the improved language development in children with GJB2-related deafness and cochlear implants. Further, genetic diagnosis of the non-syndromic hearing toss represents a useful tool for the preoperative prediction of outcomes following a cochlear implant procedure.

en-copyright= kn-copyright= en-aut-name=KawasakiAkihiro en-aut-sei=Kawasaki en-aut-mei=Akihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukushimaKunihiro en-aut-sei=Fukushima en-aut-mei=Kunihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KataokaYuko en-aut-sei=Kataoka en-aut-mei=Yuko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=FukudaShoichiro en-aut-sei=Fukuda en-aut-mei=Shoichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NishizakiKazunori en-aut-sei=Nishizaki en-aut-mei=Kazunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University en-keyword=cochlear implant kn-keyword=cochlear implant en-keyword=higher brain function kn-keyword=higher brain function en-keyword=GJB2 kn-keyword=GJB2 en-keyword=language development kn-keyword=language development en-keyword=non-syndromic hearing loss kn-keyword=non-syndromic hearing loss en-keyword=learninng disability kn-keyword=learninng disability END start-ver=1.4 cd-journal=joma no-vol=63 cd-vols= no-issue=1 article-no= start-page=o17 end-page=o20 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=200701 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Hydrogen bonding in two solid phases of phenazine-chloranilic acid (1/1) determined at 170 and 93 K en-subtitle= kn-subtitle= en-abstract= kn-abstract=The crystal structures in two solid phases, i.e. phase II stable between 146 and 253 K and phase IV below 136 K, of the title compound [phenazine-chloranilic acid (1/1), C12H8N2 center dot C6H2Cl2O4, in phase II, and phenazinium hydrogen chloranilate, C12H9N2+center dot C6HCl2O4-, in phase IV], have been determined. Both phases crystallize in P2(1), and each structure was refined as an inversion twin. In phase II, the phenazine and chloranilic acid molecules are arranged alternately through two kinds of O-H center dot center dot center dot N hydrogen bonds. In phase IV, salt formation occurs by donation of one H atom from the chloranilic acid molecule to the phenazine molecule; the resulting monocation and monoanion are linked by N-H center dot center dot center dot O and O-H center dot center dot center dot N hydrogen bonds. en-copyright= kn-copyright= en-aut-name=GotohKazuma en-aut-sei=Gotoh en-aut-mei=Kazuma kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AsajiTetsuo en-aut-sei=Asaji en-aut-mei=Tetsuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IshidaHiroyuki en-aut-sei=Ishida en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Graduate School of Integrated Basic Sciences, College of Humanities and Sciences, Nihon University affil-num=3 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University END start-ver=1.4 cd-journal=joma no-vol=64 cd-vols= no-issue=24 article-no= start-page=5800 end-page=5807 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080623 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=RhCl3/amine-catalyzed [2+2+2] cyclization of alkynes en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The RhCl3-3H(2)O/i-Pr2NEt-catalyzed [2+2+2] cyclotrimerization of alkynes has been achieved. The reaction can be widely used for various alkynes and provides tri- OF hexa-substituted benzenes regioselectively in high yields. The [2+2+2] cycloaddition of diynes and alkynes is also developed, and it affords benzene derivatives in moderate to high yields.

en-copyright= kn-copyright= en-aut-name=YoshidaKenta en-aut-sei=Yoshida en-aut-mei=Kenta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MorimotoIchiro en-aut-sei=Morimoto en-aut-mei=Ichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MitsudoKoichi en-aut-sei=Mitsudo en-aut-mei=Koichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TanakaHideo en-aut-sei=Tanaka en-aut-mei=Hideo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, affil-num=2 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=4 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University en-keyword=Rh/amine catalyst kn-keyword=Rh/amine catalyst en-keyword=cyclotrimerization kn-keyword=cyclotrimerization en-keyword=hexa-substituted benzene kn-keyword=hexa-substituted benzene END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue=24 article-no= start-page=4167 end-page=4179 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080710 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Synthesis and regioselective N- and O-alkylation of 1H- or 3H-[1,2,3]triazolo[4,5-d]pyrimidine-5,7(4H,6H)-diones (8-azaxanthines) and transformation of their 3-alkyl derivatives into 1-alkyl isomers en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Several alkylating agents, for example alkyl halides and dimethyl sulfate, were employed in aprotic Solvents Under a variety of conditions for the alkylation of mono- and disubstituted 1H- or 3H-[1,2,3]triazolo[4,5-d]pyrimidine-5,7(4H,6H)-diones, which were prepared by cyclization of the appropriate 5,6-diaminouracils with nitrous acid. The alkylation on the triazole ring in the presence of anhydrous potassium carbonate took place simultaneously at the 1- and 2-positions, with alkylation at the 2-position taking priority. Similar alkylation on the pyrimidine ring with an equivalent alkylating reagent took place only at the 4-position. The alkylation of 3,6-disubstituted derivatives at room temperature led to 5-O-alkylation accompanied by 4-N-alkylation, but at high temperature only 4-N-alkylation took place. Reaction of 3,4,6-trisubstituted derivatives with excess alkylating agent at high temperature leads to the formation of 1,4,6-trisubstituted derivatives with elimination of the 3-substituent.

en-copyright= kn-copyright= en-aut-name=IslamRafiqul en-aut-sei=Islam en-aut-mei=Rafiqul kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NagamatsuTomohisa en-aut-sei=Nagamatsu en-aut-mei=Tomohisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Drug Discovery and Development, Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry, and Pharmaceutica?l Sciences, Okayama University affil-num=2 en-affil= kn-affil=Department of Drug Discovery and Development, Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry, and Pharmaceutica?l Sciences, Okayama University en-keyword=8-azaxanthines kn-keyword=8-azaxanthines en-keyword=triazolopyrimidines kn-keyword=triazolopyrimidines en-keyword=regioselectivity kn-keyword=regioselectivity en-keyword=alkylations kn-keyword=alkylations en-keyword=heterocycles kn-keyword=heterocycles END start-ver=1.4 cd-journal=joma no-vol=45 cd-vols= no-issue=11 article-no= start-page=2327 end-page=2329 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20043 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Enantioselective construction of biaryl part in the synthesis of stegane related compounds en-subtitle= kn-subtitle= en-abstract= kn-abstract=

A Pd-mediated intramolecular aryl-aryl coupling reaction of phenyl benzoate derivatives were examined to form benzo[c]chromen-6-ones, and then enantioselective lactone-opening reaction with a borane-oxazaborolidine combination was carried out. The resulting biphenyl was transformed into a key intermediate for the stegane related compounds. The absolute configuration of the biphenyl is also discussed. Stegane and related compounds are important because of their interesting biological activities such as antileukemic properties.1 One of the most outstanding features of their chemical structures is an unsymmetrical 2,2’-disubstituted biphenyl moiety with an axial chirality (Figure 1). For the formation of such a biphenyl part in the syntheses of the stegane families, several approaches have been attempted such as photocyclization,2 Suzuki coupling,3 oxidative biaryl coupling,4 the SNAr reaction,5 Ullmann coupling,6 and the [2+2+2] three-component cyclization reaction.7

en-copyright= kn-copyright= en-aut-name=AbeHitoshi en-aut-sei=Abe en-aut-mei=Hitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakedaShigemitsu en-aut-sei=Takeda en-aut-mei=Shigemitsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FujitaTakuro en-aut-sei=Fujita en-aut-mei=Takuro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=NishiokaKeisuke en-aut-sei=Nishioka en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TakeuchiYasuo en-aut-sei=Takeuchi en-aut-mei=Yasuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HarayamaTakashi en-aut-sei=Harayama en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Okayama University en-keyword=steganone kn-keyword=steganone en-keyword=palladium kn-keyword=palladium en-keyword=phenyl benzoate kn-keyword=phenyl benzoate en-keyword=lactone concept kn-keyword=lactone concept en-keyword=biary kn-keyword=biary END start-ver=1.4 cd-journal=joma no-vol=16 cd-vols= no-issue=2 article-no= start-page=922 end-page=940 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080115 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Antitumor studies. Part 4: Design, synthesis, antitumor activity, and molecular docking study of novel 2-substituted 2-deoxoflavin-5-oxides, 2-deoxoalloxazine-5-oxides, and their 5-deaza analogs en-subtitle= kn-subtitle= en-abstract= kn-abstract=Various novel 10-alkyl-2-deoxo-2-methylthioflavin-5-oxides and their 2-alkylamino derivatives were prepared by facile nitrosative cyclization of 6-(N-alkylanilino)-2-methylthiopyrimidin-4(3H)-ones followed by nucleophilic replacement of the 2-methylthio moiety by different amines, and acidic hydrolysis of the 2-methylthio moiety afforded the corresponding flavin derivatives. 2-Deoxo-2-methylthio-5-deazaalloxazines and 2-deoxo-2-methylthioalloxazine-5-oxides were also prepared by Vilsmeier reaction and by nitrosation of 6-anilino-2-methylthiopyrimidin-4(3H)-ones, respectively. Then, they were subjected to nucleophilic replacement with appropriate amines to produce the corresponding 2-alkylamino derivatives. Regiospecific N-3-alkylation of 2-deoxo-2-methylthioalloxazine-5-oxides was carried out with various alkylating agents in the usual way, The antitumor activities against CCRF-HSB-2 and KB tumor cells have been investigated in vitro, and many compounds showed promising antitumor activities. Furthermore, AutoDock molecular docking into PTK (PDB: 1t46) has been done for lead optimization of the aforementioned compounds as potential PTK inhibitors. en-copyright= kn-copyright= en-aut-name=AliHamed I. en-aut-sei=Ali en-aut-mei=Hamed I. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AshidaNoriyuki en-aut-sei=Ashida en-aut-mei=Noriyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NagamatsuTomohisa en-aut-sei=Nagamatsu en-aut-mei=Tomohisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Drug Discovery and Development, Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University affil-num=2 en-affil= kn-affil=Biology Laboratory, Research and Development Division, Yamasa Shoyu Co. affil-num=3 en-affil= kn-affil=Department of Drug Discovery and Development, Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University en-keyword=antitumor activity kn-keyword=antitumor activity en-keyword=flavin-5-oxide kn-keyword=flavin-5-oxide en-keyword=alloxazine-5-oxide kn-keyword=alloxazine-5-oxide en-keyword=AutoDock kn-keyword=AutoDock END start-ver=1.4 cd-journal=joma no-vol=60 cd-vols= no-issue=51 article-no= start-page=11969 end-page=11975 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=200412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Reactivity of TEMPO anion as a nucleophile and its applications for selective transformations of haloalkanes or acyl halides to aldehydes en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Sodium 2,2,6,6-tetramethylpiperidine-N-oxide (TEMPO−Na+), generated by reduction of TEMPO? with sodium naphthalenide in THF, reacted with alkyl halides or acyl halides to produce O-alkylated or acylated TEMPOs, which were in turn oxidized with mCPBA or reduced with DIBAL-H to afford the corresponding aldehydes, thus accomplishing a new protocol for the halides-carbonyls conversion.

en-copyright= kn-copyright= en-aut-name=InokuchiTsutomu en-aut-sei=Inokuchi en-aut-mei=Tsutomu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KawafuchiHiroyuki en-aut-sei=Kawafuchi en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Toyama National College of Technology en-keyword=TEMPO and compounds kn-keyword=TEMPO and compounds en-keyword=Oxidation kn-keyword=Oxidation en-keyword=Reduction kn-keyword=Reduction en-keyword=mCPBA kn-keyword=mCPBA en-keyword=DIBAL-H kn-keyword=DIBAL-H en-keyword=Aldehyde kn-keyword=Aldehyde END start-ver=1.4 cd-journal=joma no-vol=49 cd-vols= no-issue=15 article-no= start-page=2363 end-page=2365 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080708 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Facile synthetic procedure for and electrochemical properties of hexa(2-thienyl)benzenes directed toward electroactive materials en-subtitle= kn-subtitle= en-abstract= kn-abstract=

In the presence of RhCl3 center dot 3H(2)O and i-Pr2NEt, the cyclotrimerization of di(2-thienyl)acetylenes proceeded smoothly to afford hexa(2-thienyl)benzenes. CV analysis of the hexa(2-thienyl)benzenes showed that they may be useful as electroactive materials.

en-copyright= kn-copyright= en-aut-name=YoshidaKenta en-aut-sei=Yoshida en-aut-mei=Kenta kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MorimotoIchiro en-aut-sei=Morimoto en-aut-mei=Ichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MitsudoKoichi en-aut-sei=Mitsudo en-aut-mei=Koichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TanakaHideo en-aut-sei=Tanaka en-aut-mei=Hideo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University affil-num=4 en-affil= kn-affil=Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University en-keyword=Rh/amine catalyst kn-keyword=Rh/amine catalyst en-keyword=cyclotrimerization kn-keyword=cyclotrimerization en-keyword=hexa(2-thienyl)benzene kn-keyword=hexa(2-thienyl)benzene en-keyword=electroactive material kn-keyword=electroactive material END start-ver=1.4 cd-journal=joma no-vol=46 cd-vols= no-issue=18 article-no= start-page=3197 end-page=3200 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20055 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Synthesis of graphislactones A-D through a palladium-mediated biaryl coupling en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The chemical synthesis of graphislactones A-D was achieved through the Pd-mediated intramolecular biaryl coupling reaction of phenyl benzoate derivatives.

en-copyright= kn-copyright= en-aut-name=AbeHitoshi en-aut-sei=Abe en-aut-mei=Hitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NishiokaKeisuke en-aut-sei=Nishioka en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TakedaShigemitsu en-aut-sei=Takeda en-aut-mei=Shigemitsu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AraiMasatsugu en-aut-sei=Arai en-aut-mei=Masatsugu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TakeuchiYasuo en-aut-sei=Takeuchi en-aut-mei=Yasuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HarayamaTakashi en-aut-sei=Harayama en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Okayama University en-keyword=Palladium kn-keyword=Palladium en-keyword=Phenyl benzoate kn-keyword=Phenyl benzoate en-keyword=Graphislactone kn-keyword=Graphislactone en-keyword=Biaryl coupling kn-keyword=Biaryl coupling END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=1 article-no= start-page=242 end-page=256 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070101 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Antitumor studies. Part 1: Design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents en-subtitle= kn-subtitle= en-abstract= kn-abstract=Novel 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides were prepared as a new class of antitumor agents and showed significant antitumor activities against NCI-H 460, HCT 116, A 431, CCRF-HSB-2, and KB cell lines. In vivo investigation, 2-deoxo-10-methyl-2-phenyl-5-deazaflavin exhibited the effective antitumor activity against A 431 human adenocarcinoma cells transplanted subcutaneously into nude mouse. Furthermore, AutoDock study has been done by binding of the flavin analogs into PTK pp60(c-src), where a good correlation between their IC50 and AutoDock binding free energy was exhibited. In particular, 2-deoxo-2-phenylflavin-5-oxides exhibited the highest potential binding affinity within the binding pocket of PTK. en-copyright= kn-copyright= en-aut-name=AliHamed I.. en-aut-sei=Ali en-aut-mei=Hamed I.. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TomitaKeiichiro en-aut-sei=Tomita en-aut-mei=Keiichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AkahoEiichi en-aut-sei=Akaho en-aut-mei=Eiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KambaraHiroto en-aut-sei=Kambara en-aut-mei=Hiroto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MiuraShinji en-aut-sei=Miura en-aut-mei=Shinji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HayakawaHiroyuki en-aut-sei=Hayakawa en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AshidaNoriyuki en-aut-sei=Ashida en-aut-mei=Noriyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KawashimaYutaka en-aut-sei=Kawashima en-aut-mei=Yutaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=YamagishiTakehiro en-aut-sei=Yamagishi en-aut-mei=Takehiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=IkeyaHisao en-aut-sei=Ikeya en-aut-mei=Hisao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=YonedaFumio en-aut-sei=Yoneda en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=NagamatsuTomohisa en-aut-sei=Nagamatsu en-aut-mei=Tomohisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University affil-num=2 en-affil= kn-affil=Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University affil-num=3 en-affil= kn-affil=Faculty of Pharmaceutical Sciences, High Technology Research Center (Life Science Center), and Center for Area Research and Development, Kobe Gakuin University affil-num=4 en-affil= kn-affil=Faculty of Pharmaceutical Sciences, High Technology Research Center (Life Science Center), and Center for Area Research and Development, Kobe Gakuin University affil-num=5 en-affil= kn-affil=Biology Laboratory, Research and Development Division, Yamasa Shoyu Co. affil-num=6 en-affil= kn-affil=Biology Laboratory, Research and Development Division, Yamasa Shoyu Co. affil-num=7 en-affil= kn-affil=Biology Laboratory, Research and Development Division, Yamasa Shoyu Co. affil-num=8 en-affil= kn-affil=Medicinal Research Laboratories, Taisho Pharmaceutical Co. affil-num=9 en-affil= kn-affil=Medicinal Research Laboratories, Taisho Pharmaceutical Co. affil-num=10 en-affil= kn-affil=Medicinal Research Laboratories, Taisho Pharmaceutical Co. affil-num=11 en-affil= kn-affil=Faculty of Pharmaceutical Sciences, Kyoto University affil-num=12 en-affil= kn-affil=Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University en-keyword=antitumor activity kn-keyword=antitumor activity en-keyword=Flavin analog kn-keyword=Flavin analog en-keyword=AutoDock kn-keyword=AutoDock en-keyword=protein tyrosine kinase kn-keyword=protein tyrosine kinase END start-ver=1.4 cd-journal=joma no-vol=74 cd-vols= no-issue= article-no= start-page=595 end-page=605 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080703 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=New dimeric flavans from gambir, an extract of Uncaria gambir en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Three new dimeric flavans, catechin-(4 alpha -> 8)-ent-epicatechin (7), gambirflavan D1 (8), and gambirflavan D2 (9), were isolated from gambir (an extract from the leaves and young twigs of Uncaria gambir), and their structures were determined based on spectroscopic and chemical data.

en-copyright= kn-copyright= en-aut-name=TaniguchiShoko en-aut-sei=Taniguchi en-aut-mei=Shoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KurodaKayo en-aut-sei=Kuroda en-aut-mei=Kayo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YoshikadoNaomi en-aut-sei=Yoshikado en-aut-mei=Naomi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=DoiKou-ichi en-aut-sei=Doi en-aut-mei=Kou-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TanabeMasahiro en-aut-sei=Tanabe en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ShibataTakashi en-aut-sei=Shibata en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=YoshidaTakashi en-aut-sei=Yoshida en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=HatanoTsutomu en-aut-sei=Hatano en-aut-mei=Tsutomu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=Faculty of Pharmaceutical Science, Okayama University affil-num=2 en-affil= kn-affil=Faculty of Pharmaceutical Science, Okayama University affil-num=3 en-affil= kn-affil=Faculty of Pharmaceutical Science, Okayama University affil-num=4 en-affil= kn-affil=Faculty of Pharmaceutical Science, Okayama University affil-num=5 en-affil= kn-affil=Faculty of Pharmaceutical Science, Okayama University affil-num=6 en-affil= kn-affil=Faculty of Pharmaceutical Science, Okayama University affil-num=7 en-affil= kn-affil=Faculty of Pharmaceutical Science, Okayama University affil-num=8 en-affil= kn-affil=Faculty of Pharmaceutical Science, Okayama University en-keyword=PROCYANIDINS kn-keyword=PROCYANIDINS END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue=19 article-no= start-page=6336 end-page=6352 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20071001 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Antitumor studies. Part 3: Design, synthesis, antitumor activity, and molecular docking study of novel 2-methylthio-, 2-amino-, and 2-(N-substituted amino)-10-alkyl-2-deoxo-5-deazaflavins en-subtitle= kn-subtitle= en-abstract= kn-abstract=Various novel 10-alkyl-2-deoxo-2-methylthio-5-deazaflavins have been synthesized by reaction of 6-(N-alkylanilino)-2-methylthiopyrimidin-4(3H)-ones with Vilsmeier reagent. The similar 2-(N-substituted amino) derivatives were prepared by nucleophilic replacement reaction of the 2-methylthio moiety by appropriate amines. The 2-oxo derivatives (i.e., 5-deazaflavins) were obtained by acidic hydrolysis of the 2-methylthio derivatives. The antitumor activities against CCRF-HSB-2 and KB cells and the antiviral activities against HSV-1 and HSV-2 have been investigated in vitro, and many compounds showed promising antitumor activities. Furthermore, AutoDock molecular docking into PTK has been done for lead optimization of these compounds as potential PTK inhibitors. Whereas, the designed 2-deoxo-5-deazaflavins connected with amino acids at the 2-position exhibited the good binding affinities into PTK with more hydrogen bonds. en-copyright= kn-copyright= en-aut-name=AliHamed I. en-aut-sei=Ali en-aut-mei=Hamed I. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AshidaNoriyuki en-aut-sei=Ashida en-aut-mei=Noriyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NagamatsuTomohisa en-aut-sei=Nagamatsu en-aut-mei=Tomohisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Drug Discovery and Development, Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University affil-num=2 en-affil= kn-affil=Biology Laboratory, Research and Development Division, Yamasa Shoyu Co. affil-num=3 en-affil= kn-affil=aDepartment of Drug Discovery and Development, Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University en-keyword=antitumor activity kn-keyword=antitumor activity en-keyword=5-deazaflavin kn-keyword=5-deazaflavin en-keyword=AutoDock kn-keyword=AutoDock en-keyword=protein tyrosine kn-keyword=protein tyrosine en-keyword=kinase kn-keyword=kinase END start-ver=1.4 cd-journal=joma no-vol=64 cd-vols= no-issue=6 article-no= start-page=1021 end-page=1025 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=200608 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Alkaline hydrothermal treatment of brominated high impact polystyrene (HIPS-Br) for bromine and bromine-free plastic recovery en-subtitle= kn-subtitle= en-abstract= kn-abstract=

A method to recover both Br and Br-free plastic from brominated flame retardant high impact polystyrene (HIPS-Br) was proposed. HIPS-Br containing 15% Br was treated in autoclave at 280℃ using water or KOH solution of various amounts and concentrations. Hydrothermal treatment (30 ml water) leads to 90% debromination of 1 g HIPS-Br but plastic is strongly degraded and could not be recovered. previous termAlkalinenext term hydrothermal treatment (45 ml or 60 ml KOH 1 M) showed similar debromination for up to 12 g HIPS-Br and plastic was recovered as pellets with molecular weight distribution close to that of the initial material. Debromination occurs at melt plastic/KOH solution interface when liquid/vapour equilibrium is attained inside autoclave (280℃ and 7 MPa in our experimental conditions) and depends on the plastic amount/KOH volume ratio. The antimony oxide synergist from HIPS-Br remains in recovered plastic during treatment. A pictorial imagination of the proposed debromination process is presented.

en-copyright= kn-copyright= en-aut-name=BrebuMihai en-aut-sei=Brebu en-aut-mei=Mihai kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=BhaskarThallada en-aut-sei=Bhaskar en-aut-mei=Thallada kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MutoAkinori en-aut-sei=Muto en-aut-mei=Akinori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SakataYusaku en-aut-sei=Sakata en-aut-mei=Yusaku kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Petru Poni Institute of Macromolecular Chemistry affil-num=2 en-affil= kn-affil=Department of Applied Chemistry, Faculty of Engineering, Okayama University affil-num=3 en-affil= kn-affil=Department of Applied Chemistry, Faculty of Engineering, Okayama University affil-num=4 en-affil= kn-affil=Department of Applied Chemistry, Faculty of Engineering, Okayama University en-keyword=Debromination kn-keyword=Debromination en-keyword=Alkaline hydrotreatment kn-keyword=Alkaline hydrotreatment en-keyword=HIPS-Br kn-keyword=HIPS-Br en-keyword=Bromine recovery kn-keyword=Bromine recovery END start-ver=1.4 cd-journal=joma no-vol=149 cd-vols= no-issue=6 article-no= start-page=2816 end-page=2825 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080625 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Aldosterone breakthrough caused by chronic blockage of angiotensin II type 1 receptors in human adrenocortical cells: Possible involvement of bone morphogenetic protein-6 actions en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Circulating aldosterone concentrations occasionally increase after initial suppression with angiotensin II (Ang II) converting enzyme inhibitors or Ang II type 1 receptor blockers (ARBs), a phenomenon referred to as aldosterone breakthrough. However, the underlying mechanism causing the aldosterone breakthrough remains unknown. Here we investigated whether aldosterone breakthrough occurs in human adrenocortical H295R cells in vitro. We recently reported that bone morphogenetic protein (BMP)-6, which is expressed in adrenocortical cells, enhances Ang II-but not potassium-induced aldosterone production in human adrenocortical cells. Accordingly, we examined the roles of BMP-6 in aldosterone breakthrough induced by long-term treatment with ARB. Ang II stimulated aldosterone production by adrenocortical cells. This Ang II stimulation was blocked by an ARB, candesartan. Interestingly, the candesartan effects on Ang II-induced aldosterone synthesis and CYP11B2 expression were attenuated in a course of candesartan treatment for 15 d. The impairment of candesartan effects on Ang II-induced aldosterone production was also observed in Ang II- or candesartanpretreated cells. Levels of Ang II type 1 receptor mRNA were not changed by chronic candesartan treatment. However, BMP-6 enhancement of Ang II- induced ERK1/2 signaling was resistant to candesartan. The BMP-6-induced Smad1, -5, and -8 phosphorylation, and BRE-Luc activity was augmented in the presence of Ang II and candesartan in the chronic phase. Chronic Ang II exposure decreased cellular expression levels of BMP-6 and its receptors activin receptor-like kinase-2 and activin type II receptor mRNAs. Cotreatment with candesartan reversed the inhibitory effects of Ang II on the expression levels of these mRNAs. The breakthrough phenomenon was attenuated by neutralization of endogenous BMP-6 and activin receptor-like kinase-2. Collectively, these data suggest that changes in BMP-6 availability and response may be involved in the occurrence of cellular escape from aldosterone suppression under chronic treatment with ARB.

en-copyright= kn-copyright= en-aut-name=OtaniHiroyuki en-aut-sei=Otani en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OtsukaFumio en-aut-sei=Otsuka en-aut-mei=Fumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=InagakiKenichi en-aut-sei=Inagaki en-aut-mei=Kenichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SuzukiJiro en-aut-sei=Suzuki en-aut-mei=Jiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MiyoshiTomoko en-aut-sei=Miyoshi en-aut-mei=Tomoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KanoYoshihiro en-aut-sei=Kano en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=GotoJunko en-aut-sei=Goto en-aut-mei=Junko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=OguraToshio en-aut-sei=Ogura en-aut-mei=Toshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=MakinoHirofumi en-aut-sei=Makino en-aut-mei=Hirofumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=2 en-affil= kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=3 en-affil= kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=4 en-affil= kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=5 en-affil= kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=6 en-affil= kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=7 en-affil= kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=8 en-affil= kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences affil-num=9 en-affil= kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences en-keyword=ENZYME-INHIBITOR THERAPY kn-keyword=ENZYME-INHIBITOR THERAPY en-keyword=CHRONIC HEART-FAILURE kn-keyword=CHRONIC HEART-FAILURE en-keyword=CONVERTING ENZYME kn-keyword=CONVERTING ENZYME en-keyword=HYPERTENSIVE PATIENTS kn-keyword=HYPERTENSIVE PATIENTS en-keyword=PLASMA-ALDOSTERONE kn-keyword=PLASMA-ALDOSTERONE en-keyword=GRANULOSA-CELLS kn-keyword=GRANULOSA-CELLS en-keyword=SYSTEM kn-keyword=SYSTEM en-keyword=SECRETION kn-keyword=SECRETION en-keyword=NEPHROPATHY kn-keyword=NEPHROPATHY en-keyword=HYPERTROPHY kn-keyword=HYPERTROPHY END start-ver=1.4 cd-journal=joma no-vol=152 cd-vols= no-issue=11 article-no= start-page=173 end-page=177 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200509 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=High-aspect-ratio copper-via-filling for three-dimensional chip stacking - II. Reduced electrodeposition process time en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Through-chip electrodes for three-dimensional packaging can offer short interconnection and reduced signal delay. Formation of suitable vias by electrodeposition into cavities presents a filling problem similar to that encountered in the damascene process. Because via dimensions for through-chip filling are larger and have a higher aspect ratio relative to features in damascene, process optimization requires modification of existing superconformal plating baths and plating parameters. In this study, copper filling of high-aspect-ratio through-chip vias was investigated and optimized with respect to plating bath composition and applied current wavetrain. Void-free vias 70 mu m deep and 10 mu m wide were formed in 60 min using additives in combination with pulse-reverse current and dissolved-oxygen enrichment. The effects of reverse current and dissolved oxygen on the performance of superfilling additives is discussed in terms of their effects on formation, destruction, and distribution of a Cu(I) thiolate accelerant. (c) 2005 The Electrochemical Society. All rights reserved.

en-copyright= kn-copyright= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YonezawaToshihiro en-aut-sei=Yonezawa en-aut-mei=Toshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MikamiDaisuke en-aut-sei=Mikami en-aut-mei=Daisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OkuboToshikazu en-aut-sei=Okubo en-aut-mei=Toshikazu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TaguchiYuichi en-aut-sei=Taguchi en-aut-mei=Yuichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TakahashiKenji en-aut-sei=Takahashi en-aut-mei=Kenji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=BarkeyDale P en-aut-sei=Barkey en-aut-mei=Dale P kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Osaka Prefecture University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Toppan Printing Company, Limited affil-num=5 en-affil= kn-affil=Tsukuba Center Incorporated affil-num=6 en-affil= kn-affil=Tsukuba Center Incorporated affil-num=7 en-affil= kn-affil=University of New Hampshire en-keyword=plating baths kn-keyword=plating baths en-keyword=additives kn-keyword=additives END start-ver=1.4 cd-journal=joma no-vol=152 cd-vols= no-issue=10 article-no= start-page=688 end-page=691 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200508 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Effect of annealing and hydrogen on properties of electrodeposited platinum electrode and lead-zirconate-titanate films for ferroelectric random access memory applications en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The selection of capacitor electrode materials for the nonvolatile ferroelectric random access memory is one of the most important issues because capacitor electrical characteristics are strongly influenced by the electrode materials. The lower Pt electrode was electrodeposited on the Ti seed/Pt seed layer. Two different thicknesses of Ti seed layer (5 and 15 nm) were adopted, and lead-zirconate-titanate (PZT) was deposited on the electrodeposited Pt. The Pt crystal orientation with a 5 nm Ti seed layer is much better than that with a 15 nm Ti seed layer, and the deposited PZT shows much better crystal orientation. Due to better crystal orientation of the PZT layer in the case of a 5 nm Ti seed layer, a Pt/PZT/Pt capacitor well-saturated D-V hysteresis loop was obtained whereas little current was observed in the large electric field. With the 15 nm Ti seed layer, numerous several-mu m-sized voids formed on the lower Pt electrode surface. With the 5 nm Ti seed layer, fewer voids formed on the lower Pt electrode surface. Glow discharge spectrometry measurement with a 15 nm Ti seed layer shows much higher H intensity than that with a 5 nm Ti seed layer, and the H peak coincides with the Ti peak. The H existing in the Ti seed layer must have transmitted into the PZT layer and deteriorated the PZT crystal orientation. (c) 2005 The Electrochemical Society.

en-copyright= kn-copyright= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=WatanabeKeiji en-aut-sei=Watanabe en-aut-mei=Keiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AbeYuji en-aut-sei=Abe en-aut-mei=Yuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HajiJunko en-aut-sei=Haji en-aut-mei=Junko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ShimizuMasaru en-aut-sei=Shimizu en-aut-mei=Masaru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Osaka Prefecture University affil-num=2 en-affil= kn-affil=Osaka Prefecture University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=University of Hyogo en-keyword=chemical-vapor-deposition kn-keyword=chemical-vapor-deposition en-keyword=electrical-properties kn-keyword=electrical-properties END start-ver=1.4 cd-journal=joma no-vol=34 cd-vols= no-issue=10 article-no= start-page=1109 end-page=1119 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200510 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Polar and hydrogen-bonding effects of alcohols on the emission spectrum of styrene-triethylamine system en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The emission spectra of styrene (ST)-triethylamine (TEA) systems were measured under steady-state illumination conditions in some THF-protic solvent mixtures. The fluorescence spectrum of the ST-TEA system in THF consists of two bands (band A at 304 nm (fluorescence of ST) and band B at 460 nm (emission from an exciplex)). The intensity of band A increased and that of band B decreased with increasing amounts of protic solvents in THF-protic solvent mixtures. The increase in the intensity of band A was explained by the decrease in the concentration of free amine owing to the hydrogen-bonding interaction (or protonation) between TEA and protic solvents. The decrease in the intensity of band B was considered to be caused by the decrease in the concentration of free amine on the addition of protic solvents and the enhanced conversion of the exciplex to an ion pair with increasing solvent polarity. The polar effect was expressed as a function of the relative permittivity of the solution.

en-copyright= kn-copyright= en-aut-name=YamamotoShunzo en-aut-sei=Yamamoto en-aut-mei=Shunzo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=Okayama University en-keyword=Solvent effect; Hydrogen-bonding; Polar effect; Exciplex; Fluorescence kn-keyword=Solvent effect; Hydrogen-bonding; Polar effect; Exciplex; Fluorescence END start-ver=1.4 cd-journal=joma no-vol=145 cd-vols= no-issue=9 article-no= start-page=3007 end-page=3010 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19989 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Shape evolution of electrodeposited bumps with deep cavity en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Electrodeposited bumps are the indispensable microconnectors for high-density interconnection in the latest microelectronics applications. The deep cavities are especially important for the solder bumps for ball grid arrays. This investigation discusses the relation between cavity shapes and current distributions of deep cavities. The role of convection and diffusion within the cavities is calculated at diffusion-limited overpotentials with numerical fluid dynamics computations. The current distributions become symmetric and peak profiles become sharper for the deeper cavities of large aspect ratios and of negative photoresist angles, theta. For 30 mu m cathode length, the current at the center is larger than that at the edges for photoresist angles of theta less than or equal to 0. For these deep cavities, the convection outside the cavity is not related to the current distribution and the current distribution is determined by the cavity shape. The mass transport within the deep cavities is controlled mainly by diffusion. This is because the convection outside the cavities is not effectively stirring inside the deep cavities.

en-copyright= kn-copyright= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukuiKeisuke en-aut-sei=Fukui en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Himeji Institute of Technology en-keyword=copper bumps kn-keyword=copper bumps END start-ver=1.4 cd-journal=joma no-vol=123 cd-vols= no-issue=9 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050901 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Formation of ice nanotube with hydrophobic guests inside carbon nanotube en-subtitle= kn-subtitle= en-abstract= kn-abstract=A composite ice nanotube inside a carbon nanotube has been explored by molecular dynamics and grandcanonical Monte Carlo simulations. It is made from an octagonal ice nanotube whose hollow space contains hydrophobic guest molecules such as neon, argon, and methane. It is shown that the attractive interaction of the guest molecules stabilizes the ice nanotube. The guest occupancy of the hollow space is calculated by the same method as applied to clathrate hydrates. en-copyright= kn-copyright= en-aut-name=TanakaHideki en-aut-sei=Tanaka en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KogaKenichiro en-aut-sei=Koga en-aut-mei=Kenichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University en-keyword=ice nanotubes kn-keyword=ice nanotubes en-keyword=carbon nanotubes kn-keyword=carbon nanotubes END start-ver=1.4 cd-journal=joma no-vol=151 cd-vols= no-issue=7 article-no= start-page=514 end-page=518 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20046 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Crystal growth of electrolytic cu foil en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Electrolytic copper deposited on (100)(Cu) single crystals forms pyramidal crystals that grow parallel to the substrate at low current density without stirring. With stirring and higher current density, slanting platelet crystals with (111)(Cu) orientation are formed. Chloride and gelatin are typical additives for electrolytic copper foils and the electrolytic copper foils are formed on a titanium substrate with a stirring rate and high current density. With gelatin, triangular pyramidal crystals form with (111)(Cu) orientation. The triangle-shaped side planes of the crystals are the (100)(Cu), and platelet crystals exist along the (100)(Cu). With chloride and gelatin, triangular columnar crystals with the (110)(Cu) orientation are formed. The triangle-shaped side planes of the crystals are the (100)(Cu) and the platelet crystals again exist along the (100)(Cu). These platelet crystals are bound by macrosteps, and they are the growth sites. The morphology of electrolytic copper foils on the titanium substrate does not change with higher current densities and stirring rates. It was also found that chloride changes deposit orientations in the concentration range of less than 10 ppm. (C) 2004 The Electrochemical Society.

en-copyright= kn-copyright= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MurakamiHaruo en-aut-sei=Murakami en-aut-mei=Haruo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University en-keyword=sulfate kn-keyword=sulfate en-keyword=copper kn-keyword=copper en-keyword=baths kn-keyword=baths END start-ver=1.4 cd-journal=joma no-vol=162 cd-vols= no-issue=2 article-no= start-page=1322 end-page=1328 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=200610 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Properties of a novel hard-carbon optimized to large size Lion secondary battery studied by 7Li NMR en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The state of lithium in a novel hard-carbon optimized to the anode of large size Li ion secondary battery, which has been recently commercialized, was investigated and compared with other existing hard-carbon samples by 7Li NMR method. The new carbon material showed a peak at 85 ppm with a shoulder signal at 7 ppm at room temperature in static NMR spectrum, and the former shifted to 210 ppm at 180 K. The latter at room temperature was attributed to Li doped in small particles contained in the sample. The new carbon sample showed weaker intensity of cluster-lithium signal than the other hard-carbon samples in NMR, which corresponded to a tendency of less "Constant Voltage" (CV) capacity in charge-discharge curves of electrochemical evaluation. Smaller CV capacity and initial irreversible capacity, which are the features of the novel hard-carbon, are considered to correspond to a blockade of the diffusion of Li into pore of carbon.

en-copyright= kn-copyright= en-aut-name=GotohKazuma en-aut-sei=Gotoh en-aut-mei=Kazuma kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MaedaMariko en-aut-sei=Maeda en-aut-mei=Mariko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NagaiAisaku en-aut-sei=Nagai en-aut-mei=Aisaku kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=GotoAtsushi en-aut-sei=Goto en-aut-mei=Atsushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TanshoMasataka en-aut-sei=Tansho en-aut-mei=Masataka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HashiKenjiro en-aut-sei=Hashi en-aut-mei=Kenjiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ShimizuTadashi en-aut-sei=Shimizu en-aut-mei=Tadashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=IshidaHiroyuki en-aut-sei=Ishida en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Kureha Corporation affil-num=3 en-affil= kn-affil=Kureha Corporation affil-num=4 en-affil= kn-affil=National Institute for Materials Science affil-num=5 en-affil= kn-affil=National Institute for Materials Science affil-num=6 en-affil= kn-affil=National Institute for Materials Science affil-num=7 en-affil= kn-affil=National Institute for Materials Science affil-num=8 en-affil= kn-affil=Okayama University en-keyword=hard carbon kn-keyword=hard carbon en-keyword=Lithium kn-keyword=Lithium en-keyword=battery kn-keyword=battery en-keyword=7Li NMR kn-keyword=7Li NMR en-keyword=anode kn-keyword=anode en-keyword=electric vehicle kn-keyword=electric vehicle END start-ver=1.4 cd-journal=joma no-vol=148 cd-vols= no-issue=3 article-no= start-page=145 end-page=148 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=200103 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Shape evolution of electrodeposited bumps into deep cavities en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Metal posts and finer pitch solder bumps are the indispensable microconnectors for chip size packaging and are formed by electrodeposition into deep cavities. It is difficult to stir inside these deep cavities. Natural convection due to density difference is effective in stirring inside cavity with 200 mum cathode width of aspect ratio of one. The bump shape increases toward lower side in a vertical cathode arrangement with placement angle of Theta = 90 degrees. This increase in bump height results from a collision of flow along the lower side of the resist sidewall which enlarges local current and thickens the lower edge of bumps. The effect of natural convection is also evident in the neighboring two cavities of 200 mum cathode width. The natural convection is not effective for cavities with less than 100 mum cathode width. The bump shapes become flat. Only diffusion occurs within these smaller than 100 mum cavities. (C) 2001 The Electrochemical Society. All rights reserved.

en-copyright= kn-copyright= en-aut-name=HayashiK en-aut-sei=Hayashi en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukuiKeisuke en-aut-sei=Fukui en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TanakaZenzo en-aut-sei=Tanaka en-aut-mei=Zenzo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Himeji Institute of Technology affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=copper bumps kn-keyword=copper bumps END start-ver=1.4 cd-journal=joma no-vol=54 cd-vols= no-issue=3-4 article-no= start-page=233 end-page=239 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20064 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Elucidation of the role of the complex in hydride transfer reaction between methylene blue and 1-benzyl-1,4-dihydronictinamide by effect of γ-cyclodextrin en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The kinetics of the hydride transfer reaction between Methylene Blue (MB+) and　1-benzyl-1,4-dihydronicotinamide (BNAH) were studied in 10 % ethanol-90 % water mixed solvents containing β- and γ-cyclodextrins (β-CD and γ-CD). The pseudo-first order rate constant shows kinetic saturation at high initial concentration of BNAH. This indicates the formation of a complex between MB+ and BNAH. The reaction was suppressed by addition of β-CD, but enhanced by addition of γ-CD. MB+ and BNAH were separately accommodated within the β-CD cavity and the cavity walls may protect the activity site of the reactants. On the other hand, in the MB+-BNAH-γ-CD system, the inclusion of the complex between MB+ and BNAH with γ-CD occurred. This effect of γ-CD can distinguish between the productive and non-productive nature of the complex.

en-copyright= kn-copyright= en-aut-name=LiuYingin en-aut-sei=Liu en-aut-mei=Yingin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HotouchiNaoto en-aut-sei=Hotouchi en-aut-mei=Naoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SueishiYoshimi en-aut-sei=Sueishi en-aut-mei=Yoshimi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamamotoShunzo en-aut-sei=Yamamoto en-aut-mei=Shunzo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=hydride transfer reaction kn-keyword=hydride transfer reaction en-keyword=reaction mechanism kn-keyword=reaction mechanism en-keyword=cyclodextrin kn-keyword=cyclodextrin en-keyword=inclusion complexes kn-keyword=inclusion complexes en-keyword=1-benzyl-1 kn-keyword=1-benzyl-1 en-keyword=4-dihydronicotinamide kn-keyword=4-dihydronicotinamide en-keyword=Methylene Blue kn-keyword=Methylene Blue END start-ver=1.4 cd-journal=joma no-vol=92 cd-vols= no-issue=14 article-no= start-page=145503 end-page=1 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20044 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Bridging the gap between small clusters and nanodroplets: spectroscopic study and computer simulation of carbon dioxide solvated with helium atoms. en-subtitle= kn-subtitle= en-abstract= kn-abstract=

High resolution infrared spectra of HeN?CO2 clusters with N up to about 20 have been studied in the region of the CO2 v3 fundamental band. The B rotational constant initially drops as expected for a normal molecule, reaching a minimum for N = 5. Its subsequent rise for N = 6 to 11 can be interpreted as the transition from a normal (though floppy) molecule to a quantum solvation regime. For N > 13, the B value becomes approximately constant with a value about 17% larger than that measured in much larger helium nanodroplets. Quantum Monte Carlo calculations of pure rotational spectra are in excellent agreement with the measured B in this size range, and complement the experimental study with detailed structural information. For larger cluster size (N = 30-50) the simulations show a clear sign of convergence towards the nanodroplet B value.

en-copyright= kn-copyright= en-aut-name=TangJian en-aut-sei=Tang en-aut-mei=Jian kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=McKellarRobert A en-aut-sei=McKellar en-aut-mei=Robert A kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MezzacapoFabio en-aut-sei=Mezzacapo en-aut-mei=Fabio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MoroniSaverio en-aut-sei=Moroni en-aut-mei=Saverio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Steacie Institute for Molecular Science affil-num=3 en-affil= kn-affil=Universit? di Roma La Sapienza affil-num=4 en-affil= kn-affil=Universit? di Roma La Sapienza en-keyword=infrared spectroscopy kn-keyword=infrared spectroscopy en-keyword=helium cluster kn-keyword=helium cluster en-keyword=molecular superfluidity kn-keyword=molecular superfluidity en-keyword=computer simulation kn-keyword=computer simulation END start-ver=1.4 cd-journal=joma no-vol=826 cd-vols= no-issue=1 article-no= start-page=1 end-page=5 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20065 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Cl-35 NQR study of lattice dynamic and magnetic property of a crystalline coordination polymer {CuCA(phz)(H2O)2}n en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Copper(II) compounds {CuCA(phz)(H2O)2}n (H2CA = chloranilic acid, phz = phenazine) having a layer structure of -CuCA(H2O)2- polymer chains and phenazine was studied by 35Cl nuclear quadrupole resonance (NQR). The single NQR line observed at 35.635 MHz at 261.5 K increased to 35.918 MHz at 4.2 K. The degree of reduction of electric field gradient due to lattice vibrations was similar to that of chloranilic acid crystal. Temperature dependence of spin-lattice relaxation time, T1, of the 35Cl NQR signal below 20 K, between 20 and 210 K, and above 210 K, was explained by 1) a decrease of effective electron-spin density caused by antiferromagnetic interaction, 2) a magnetic interaction between Cl nuclear-spin and electron-spins on paramagnetic Cu(II) ions, and 3) an increasing contribution from reorientation of ligand molecules, respectively. The electron spin-exchange parameter |J| between the neighboring Cu(II) electrons was estimated to be 0.33 cm?1 from the T1 value of the range 20?210 K. Comparing this value with that of J = ?1.84 cm?1 estimated from the magnetic susceptibility, it is suggested that the magnetic dipolar 2 coupling with the electron spins on Cu(II) ions must be the principal mechanism for the 35Cl NQR spin-lattice relaxation of {CuCA(phz)(H2O)2}n but a delocalization of electron spin over the chloranilate ligand have to be taken into account.

en-copyright= kn-copyright= en-aut-name=GotohKazuma en-aut-sei=Gotoh en-aut-mei=Kazuma kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TeraoTakeshi en-aut-sei=Terao en-aut-mei=Takeshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AsajiTetsuo en-aut-sei=Asaji en-aut-mei=Tetsuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Nihon University affil-num=3 en-affil= kn-affil=Nihon University en-keyword=crystalline coordination polymer kn-keyword=crystalline coordination polymer en-keyword=paramagnetic kn-keyword=paramagnetic en-keyword=nuclear resonance kn-keyword=nuclear resonance en-keyword=spin-lattice relaxation kn-keyword=spin-lattice relaxation en-keyword=spin exchange kn-keyword=spin exchange END start-ver=1.4 cd-journal=joma no-vol=145 cd-vols= no-issue=3 article-no= start-page=840 end-page=844 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19983 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Current evolution of electrodeposited copper bumps with photoresist angle en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We report the current distribution of copper bumps with photoresist sidewall angles. The role of outer diffusion, vortices, and penetration flow within the cavity is discussed, with numerical fluid dynamics computed in order to prevent side bumping. The current distributions were calculated at the diffusion controlled overpotential. The mass transfer-limited current distribution showed that a zero or negative angle reduced diffusion from the outer surroundings and enhanced vortex formation at the cathode corners. Reduction in the diffusion and enhancement in vortices reduced current at the cathode corners and prevented side bumping.

en-copyright= kn-copyright= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukuiKeisuke en-aut-sei=Fukui en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Himeji Institute of Technology en-keyword=shape evolution kn-keyword=shape evolution en-keyword=foil kn-keyword=foil en-keyword=transport kn-keyword=transport END start-ver=1.4 cd-journal=joma no-vol=123 cd-vols= no-issue=11 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20059 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Infrared spectra of seeded hydrogen clusters: (para-H2)N-N2O and (ortho-H2)N-N2O, N=2-13 en-subtitle= kn-subtitle= en-abstract= kn-abstract=

High-resolution infrared spectra of clusters containing para-H2 and/or ortho-H2 and a single nitrous oxide molecule are studied in the 2225-cm?1 region of the 1 fundamental band of N2O. The clusters are formed in pulsed supersonic jet expansions from a cooled nozzle and probed using a tunable infrared diode laser spectrometer. The simple symmetric rotor-type spectra generally show no resolved K structure, with prominent Q-branch features for ortho-H2 but not para-H2 clusters. The observed vibrational shifts and rotational constants are reported. There is no obvious indication of superfluid effects for para-H2 clusters up to N=13. Sharp transitions due to even larger clusters are observed, but no definite assignments are possible. Mixed (para-H2)N?(ortho-H2)M?N2O cluster line positions can be well predicted by linear interpolation between the corresponding transitions of the pure clusters.

en-copyright= kn-copyright= en-aut-name=TangJian en-aut-sei=Tang en-aut-mei=Jian kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=McKellarRobert A en-aut-sei=McKellar en-aut-mei=Robert A kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Steacie Institute for Molecular Science en-keyword=vibrational kn-keyword=vibrational en-keyword=rotational kn-keyword=rotational en-keyword=infrared spectroscopy kn-keyword=infrared spectroscopy en-keyword=gas phase kn-keyword=gas phase en-keyword=superfluidity kn-keyword=superfluidity END start-ver=1.4 cd-journal=joma no-vol=151 cd-vols= no-issue=4 article-no= start-page=250 end-page=255 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20042 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Role of additives for copper damascene electrodeposition experimental study on inhibition and acceleration effects en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The role of copper Damascene additives is discussed based on electrodeposit morphology on a through-mask cathode, field emission-Auger (FE-Auger), quartz crystal microbalance (QCM), and electrochemical measurements. Adsorbed particles, several tens of nanometers in diameter were observed on copper-electrodeposited surfaces by field emission-scanning electron microscopy (FE-SEM). These particles show a stronger oxygen intensity peak by FE-Auger spectrum than bare electrodeposited surfaces. The QCM frequency deviation did not increase with time in the CuSO4 and H2SO4 bath without polyethylene glycol (PEG) and chloride ion (Cl-) additives. When the substrates were immersed in the bath with these additives, the deviation markedly increased with time. Numerous PEG molecules were observed by FE-SEM immersed after 1000 s. The current density remained constant at a low value for the bath with PEG and Cl- additives. The current density started to increase markedly with time just after adding 1 ppm of bis(3-sulfopropyl) disulfide (SPS). Numerous PEG molecules were present on the electrodeposits before adding SPS. No PEG molecules, however, remained on the surface once SPS was added to the bath. The current density increased with narrower opening widths of the through-mask cathode. Despite this increase, the deposit cross sections on narrower opening widths of 2 and 10 mum were flat and no curvatures were found. Hence, the deposit curvature is not the origin of the acceleration effect. (C) 2004 The Electrochemical Society.

en-copyright= kn-copyright= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MatsumotoToshiaki en-aut-sei=Matsumoto en-aut-mei=Toshiaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=WatanabeKeiji en-aut-sei=Watanabe en-aut-mei=Keiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University en-keyword=polyethylene-glycol kn-keyword=polyethylene-glycol en-keyword=deposition kn-keyword=deposition END start-ver=1.4 cd-journal=joma no-vol=151 cd-vols= no-issue=7 article-no= start-page=514 end-page=518 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20046 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Development of cu-core pb-free solder bumps en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Cu-core Pb-free solder bumps were developed by electrodeposition in combination with photolithography. A bump with a pitch of 100 mum and a diam of 50 mum was successfully achieved with dry film resist (80 mum thick) under optimum process conditions, and the bumps reached the target height of 50 6 5 mm. The adoption of a dummy pattern improved the height uniformity of the bumps. Pull test results showed that the shear strength of the Cu bump (around 45 gf) was obtained by the soft-etching pretreatment of the Cu foil surface. Sn-Zn, Sn-Ag, Sn-Cu, and Sn-Bi platings were deposited as Pb-free solders with near-eutectic compositions. In particular, the interface properties of Sn-Zn solder plating/Cu were investigated after reflowing in this study, as well as the effect of Ni plating as an under ball metallurgy layer on compound formation at the interface. It was found that a compound of Y-Cu5Zn8 layer existed in the interface of the reflowed Sn-Zn plating/Cu. The Ni plating layer inhibited the formation of the interface Y-Cu5Zn8 compound with reflowing. (C) 2004 The Electrochemical Society.

en-copyright= kn-copyright= en-aut-name=MuDaobin en-aut-sei=Mu en-aut-mei=Daobin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MaedaJunpei en-aut-sei=Maeda en-aut-mei=Junpei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University en-keyword=electrodeposited copper bumps kn-keyword=electrodeposited copper bumps en-keyword=shape evolution kn-keyword=shape evolution en-keyword=lead kn-keyword=lead en-keyword=alloys kn-keyword=alloys END start-ver=1.4 cd-journal=joma no-vol=140 cd-vols= no-issue=2 article-no= start-page=362 end-page=365 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19932 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Codeposition of a-alumina particles from acid copper sulfate bath en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The purpose of this work is to elucidate the factors affecting the codeposition of a-alumina particles with copper from an acid copper sulfate bath. The effect of current density and particle concentration in the bath on the amount of codeposited a-alumina were determined. In order to evaluate the surface-chemical properties of the particles, the zeta-potential of a-alumina particles in the plating bath was determined by means of the streaming potential method. The amounts of adsorbed Cu 2+ and SO2( from the plating bath were also determined. The amount of codeposited a-alumina particles was found to be greater than those reported in literature, in spite of the negative zeta-potential values of a-alumina. This indicates that the electrostatic interaction between the particles and the cathode is not the essential factor of the codeposition process. It is considered that the amount of adsorbed Cu 2+ on the a-alumina particle plays an important role in the codeposition behavior.

en-copyright= kn-copyright= en-aut-name=HayashiHidetaka en-aut-sei=Hayashi en-aut-mei=Hidetaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IzumiShin-ya en-aut-sei=Izumi en-aut-mei=Shin-ya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TariIsao en-aut-sei=Tari en-aut-mei=Isao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University en-keyword=Deposition kn-keyword=Deposition en-keyword=Kinetics kn-keyword=Kinetics END start-ver=1.4 cd-journal=joma no-vol=152 cd-vols= no-issue=11 article-no= start-page=173 end-page=177 dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200509 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=High-aspect-ratio copper via filling used for three-dimensional chip stacking en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Through-chip electrodes for three-dimensional packaging can offer short interconnection and reduced signal delay. Formation of suitable vias by electrodeposition into cavities presents a filling problem similar to that encountered in the damascene process. Because via dimensions for through-chip filling are larger and have a higher aspect ratio relative to features in damascene, process optimization requires modification of existing superconformal plating baths and plating parameters. In this study, copper filling of high-aspect-ratio through-chip vias was investigated and optimized with respect to plating bath composition and applied current wavetrain. Void-free vias 70 mu m deep and 10 mu m wide were formed in 60 min using additives in combination with pulse-reverse current and dissolved-oxygen enrichment. The effects of reverse current and dissolved oxygen on the performance of superfilling additives is discussed in terms of their effects on formation, destruction, and distribution of a Cu(I) thiolate accelerant. (c) 2005 The Electrochemical Society. All rights reserved.

en-copyright= kn-copyright= en-aut-name=SunJian-Jun en-aut-sei=Sun en-aut-mei=Jian-Jun kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OkamuraTakuji en-aut-sei=Okamura en-aut-mei=Takuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OhSeungJin en-aut-sei=Oh en-aut-mei=SeungJin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TomisakaManabu en-aut-sei=Tomisaka en-aut-mei=Manabu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=YonemuraHitoshi en-aut-sei=Yonemura en-aut-mei=Hitoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=HoshinoMasataka en-aut-sei=Hoshino en-aut-mei=Masataka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TakahashiKenji en-aut-sei=Takahashi en-aut-mei=Kenji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Tsukuba Research Center affil-num=6 en-affil= kn-affil=Tsukuba Research Center affil-num=7 en-affil= kn-affil=Tsukuba Research Center affil-num=8 en-affil= kn-affil=Tsukuba Research Center en-keyword=plating baths kn-keyword=plating baths en-keyword=additives kn-keyword=additives END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=1 article-no= start-page=147 end-page=152 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Observation of micropores in hard-carbon using Xe-129 NMR porosimetry en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The existence of micropores and the change of surface structure in pitch-based hard-carbon in xenon atmosphere were demonstrated using Xe-129 NMR. For high-pressure (4.0 MPa) Xe-129 NMR measurements, the hard-carbon samples in Xe gas showed three peaks at 27, 34 and 210 ppm. The last was attributed to the xenon in micropores (<1 nm) in hard-carbon particles. The NMR spectrum of a sample evacuated at 773 K and exposed to 0.1 MPa Xe gas at 773 K for 24 h showed two peaks at 29 and 128 ppm, which were attributed, respectively, to the xenon atoms adsorbed in the large pores (probably mesopores) and micropores of hard-carbon. With increasing annealing time in Xe gas at 773 K, both peaks shifted and merged into one peak at 50 ppm. The diffusion of adsorbed xenon atoms is very slow, probably because the transfer of molecules or atoms among micropores in hard-carbon does not occur readily. Many micropores are isolated from the outer surface. For that reason, xenon atoms are thought to be adsorbed only by micropores near the surface, which are easily accessible from the surrounding space.

en-copyright= kn-copyright= en-aut-name=GotohKazuma en-aut-sei=Gotoh en-aut-mei=Kazuma kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=UedaTakahiro en-aut-sei=Ueda en-aut-mei=Takahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OmiHironori en-aut-sei=Omi en-aut-mei=Hironori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=EguchiTaro en-aut-sei=Eguchi en-aut-mei=Taro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MaedaMariko en-aut-sei=Maeda en-aut-mei=Mariko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=MiyaharaMichihisa en-aut-sei=Miyahara en-aut-mei=Michihisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AisakuNagai en-aut-sei=Aisaku en-aut-mei=Nagai kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=IshidaHiroyuki en-aut-sei=Ishida en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=The Museum of Osaka University affil-num=3 en-affil= kn-affil=The Museum of Osaka University affil-num=4 en-affil= kn-affil=The Museum of Osaka University affil-num=5 en-affil= kn-affil=Research Center, Kureha Corporation affil-num=6 en-affil= kn-affil=Research Center, Kureha Corporation affil-num=7 en-affil= kn-affil=Research Center, Kureha Corporation affil-num=8 en-affil= kn-affil=Okayama University en-keyword=amorphous materials kn-keyword=amorphous materials en-keyword=microporous materials kn-keyword=microporous materials en-keyword=nuclear magnetic resonance (NMR) kn-keyword=nuclear magnetic resonance (NMR) END start-ver=1.4 cd-journal=joma no-vol=144 cd-vols= no-issue=2 article-no= start-page=466 end-page=470 dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=19972 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Shape evolution of electrodeposited copper bumps with high peclet numbers en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We report the shape evolution of initial copper bumps at Peclet numbers higher than a hundred. The role of vortices and of penetration flow within the cavity was discussed with numerical fluid dynamics computation to obtain a bump with a single hump at the center. The current distributions, or flux profiles, were calculated at the diffusion controlled overpotential and were compared with the electrodeposited bump shapes. For the 100 mu m cavity width, the vortices increase at the upstream corners with Peclet numbers 1410 and 7311. The vortices are the local resistance of mass transfer to the cathode. These vortices cause the hollows in flux profiles at the upstream corner with these Peclet numbers. The penetration flow collides with the photoresist sidewall and the vortices decrease at downstream corners. These decreased vortices cause the increase in flux profile at downstream corners. For a 30 pm cavity width a single large vortex forms for the higher Peclet number 44,500 and a single hump in flux is achieved.

en-copyright= kn-copyright= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FukuiKeisuke en-aut-sei=Fukui en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YokoyamaMitsunori en-aut-sei=Yokoyama en-aut-mei=Mitsunori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ShinoharaKunio en-aut-sei=Shinohara en-aut-mei=Kunio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Himeji Institute of Technology affil-num=3 en-affil= kn-affil=University of Hokkaido affil-num=4 en-affil= kn-affil=University of Hokkaido en-keyword=foil kn-keyword=foil en-keyword=transport kn-keyword=transport en-keyword=cavities kn-keyword=cavities END start-ver=1.4 cd-journal=joma no-vol=147 cd-vols= no-issue=7 article-no= start-page=2611 end-page=2613 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=200007 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Electrodeposition of Zinc-SiO2 composite en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The incorporation mechanism of SiO2 particles into zinc electrodeposit is discussed. The SiO2 particles precipitate in two ways on the (00-1)(eta) of zinc electrodeposit: by lined up particles along the laterally growing macrosteps on the (00.1)(eta) and by randomly dispersed particles on the (00.1)(eta). These particles incorporate into the electrodeposits by following two processes. The sidewalls of particles are incorporated into the macrosteps at the edge of (00.1)(eta). The bottom of randomly dispersed particles are incorporated into the (00.1)(eta) probably by the atomic steps. (C) 2000 The Electrochemical Society.

en-copyright= kn-copyright= en-aut-name=KondoKazuo en-aut-sei=Kondo en-aut-mei=Kazuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=OhgishiAtsufumi en-aut-sei=Ohgishi en-aut-mei=Atsufumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TanakaZennosuke en-aut-sei=Tanaka en-aut-mei=Zennosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University en-keyword=atomic-force microscopy kn-keyword=atomic-force microscopy en-keyword=iron binary alloy kn-keyword=iron binary alloy en-keyword=zinc kn-keyword=zinc en-keyword=morphology microstructure kn-keyword=morphology microstructure END start-ver=1.4 cd-journal=joma no-vol=140 cd-vols= no-issue=2 article-no= start-page=386 end-page=389 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19932 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Studies on the acid-base properties of the ZnBr2NaBr molten salt system en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The acid-base properties of the ZnBr2-NaBr melts at 623 K were investigated on the basis of the electromotive force measurements of a zinc-zinc concentration cell. The following two chemical equilibria were postulated to describe the acid-base character of the melts.

en-copyright= kn-copyright= en-aut-name=HayashiHidetaka en-aut-sei=Hayashi en-aut-mei=Hidetaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=UnoKiyofumi en-aut-sei=Uno en-aut-mei=Kiyofumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TakeharaZen-ichiro en-aut-sei=Takehara en-aut-mei=Zen-ichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KatagiriAkira en-aut-sei=Katagiri en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Kyoto University affil-num=3 en-affil= kn-affil=Kyoto University affil-num=4 en-affil= kn-affil=Kyoto University en-keyword=alcl3-nacl melts kn-keyword=alcl3-nacl melts en-keyword=equilibria kn-keyword=equilibria END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=5 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20059 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Electron- and neutrino-nucleus scattering in the impulse approximation regime en-subtitle= kn-subtitle= en-abstract= kn-abstract=

A quantitative understanding of the weak nuclear response is a prerequisite for the analyses of neutrino experiments such as K2K and MiniBOONE, which measure energy and angle of the muons produced in neutrino-nucleus interactions in the energy range 0.5-3 GeV and reconstruct the incident neutrino energy to determine neutrino oscillations. In this paper we discuss theoretical calculations of electron- and neutrino-nucleus scattering, carried out within the impulse approximation scheme using realistic nuclear spectral functions. Comparison between electron scattering data and the calculated inclusive cross section of oxygen, at beam energies ranging between 700 and 1200 MeV, show that the Fermi gas model, widely used in the analysis of neutrino oscillation experiments, fails to provide a satisfactory description of the measured cross sections, and inclusion of nuclear dynamics is needed.

en-copyright= kn-copyright= en-aut-name=BenherOmar en-aut-sei=Benher en-aut-mei=Omar kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=FarinaNicola en-aut-sei=Farina en-aut-mei=Nicola kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NakamuraHiroki en-aut-sei=Nakamura en-aut-mei=Hiroki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SakudaMakoto en-aut-sei=Sakuda en-aut-mei=Makoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SekiRyoichi en-aut-sei=Seki en-aut-mei=Ryoichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Ist Nazl Fis Nucl affil-num=2 en-affil= kn-affil=University of Roma La Sapienza affil-num=3 en-affil= kn-affil=Waseda University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=California State University en-keyword=monte-carlo calculations kn-keyword=monte-carlo calculations en-keyword=spectal-function kn-keyword=spectal-function en-keyword=proton propagation kn-keyword=proton propagation en-keyword=e kn-keyword=e en-keyword=e'p kn-keyword=e'p en-keyword=peactions kn-keyword=peactions en-keyword=cross-section kn-keyword=cross-section en-keyword=light-nucle? kn-keyword=light-nucle? en-keyword=matter kn-keyword=matter en-keyword=o-16 kn-keyword=o-16 en-keyword=transparency kn-keyword=transparency en-keyword=oscillation kn-keyword=oscillation END start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue=5 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20063 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Search for anomalous couplings in top decay at hadron colliders en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We present a quantitative study on sensitivities to the top-decay anomalous couplings, taking into account realistic experimental conditions expected at Tevatron and LHC. A double angular distribution of W and charged lepton in the top-decay is analyzed, using t<(t)<($)over bar> events in the leptons+jets channel. In order to improve sensitivities to the anomalous couplings, we apply two techniques: (i) We use a likelihood fitting method for full kinematical reconstruction of each top event. (ii) We develop a new effective spin reconstruction method for leptonically-decayed top quarks; this method does not require spin information of the antitop side. For simplicity, we neglect couplings of right-handed bottom quark as well as CP violating couplings. The 95% C.L. estimated bound on a ratio of anomalous couplings reads -0.81 < f(2)/f(1)<-0.70, -0.12 < f(2)/f(1)< 0.14 using 1000 reconstructed top events at Tevatron, while -0.74 < f(2)/f(1)<-0.72, -0.01 < f(2)/f(1)< 0.01 is expected with 100 k reconstructed top events at LHC, where only statistical errors are taken into account. A two-fold ambiguity in the allowed range remains when the number of events exceeds a few hundred.

en-copyright= kn-copyright= en-aut-name=TsunoS en-aut-sei=Tsuno en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NakanoI en-aut-sei=Nakano en-aut-mei=I kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TanakaR en-aut-sei=Tanaka en-aut-mei=R kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University en-keyword=quark pair production kn-keyword=quark pair production en-keyword=order qcd correction kn-keyword=order qcd correction en-keyword=spin correlations kn-keyword=spin correlations en-keyword=linear kn-keyword=linear en-keyword=colliders kn-keyword=colliders en-keyword=charged leptons kn-keyword=charged leptons en-keyword=width kn-keyword=width en-keyword=thvatron kn-keyword=thvatron en-keyword=collisions kn-keyword=collisions en-keyword=threshold kn-keyword=threshold END start-ver=1.4 cd-journal=joma no-vol=456 cd-vols= no-issue=4 article-no= start-page=687 end-page=691 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080626 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Barley plasma membrane intrinsic proteins (PIP aquaporins) as water and CO2 transporters en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We identified barley aquaporins and demonstrated that one, HvPIP2;1, transports water and CO2. Regarding water homeostasis in plants, regulations of aquaporin expression were observed in many plants under several environmental stresses. Under salt stress, a number of plasma membrane-type aquaporins were down-regulated, which can prevent continuous dehydration resulting in cell death. The leaves of transgenic rice plants that expressed the largest amount of HvPIP2;1 showed a 40% increase in internal CO2 conductance compared with leaves of wild-type rice plants. The rate of CO2 assimilation also increased in the transgenic plants. The goal of our plant aquaporin research is to determine the key aquaporin species responsible for water and CO2 transport, and to improve plant water relations, stress tolerance, CO2 uptake or assimilation, and plant productivity via molecular breeding of aquaporins.

en-copyright= kn-copyright= en-aut-name=KatsuharaMaki en-aut-sei=Katsuhara en-aut-mei=Maki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=HanbaYuko T. en-aut-sei=Hanba en-aut-mei=Yuko T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Research Institute for Bioresources, Okayama University affil-num=2 en-affil= kn-affil=Center for Bioresource Field Science, Kyoto Institute of Technology en-keyword=barley kn-keyword=barley en-keyword=CO2 kn-keyword=CO2 en-keyword=plant aquaporins kn-keyword=plant aquaporins en-keyword=salt stress kn-keyword=salt stress en-keyword=water transport kn-keyword=water transport END start-ver=1.4 cd-journal=joma no-vol=353 cd-vols= no-issue=1-2 article-no= start-page=28 end-page=34 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080529 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Albumin-conjugated PEG liposome enhances tumor distribution of liposomal doxorubicin in rats en-subtitle= kn-subtitle= en-abstract= kn-abstract=

To evaluate the effect of coupling of recombinant human serum albumin (rHSA) onto the surface of poly(ethylene glycol)-modified liposorne (PEG liposome) on the in vivo disposition characteristics of liposomal doxorubicin (DXR), the pharmacokinetics and tissue distribution of DXR were evaluated after intravenous administration of rHSA-modified PEG (rHSA/PEG) liposomal DXR into tumor-bearing rats. rHSA/PEG liposome prepared using a hetero-bifunctional cross-linker, N- succinimidyl 3-(2-pyridyldithio) propionate (SPDP), efficiently encapsulated DXR (over 95%). rHSA/PEG liposomal DXR showed longer blood-circulating property than PEG liposornal DXR and the hepatic and splenic clearances of rHSA/PEG liposornal DXR were significantly smaller than those of PEG liposomal DXR. It was also demonstrated that the disposition of DXR to the heart, one of the organs for DXR-related side-effects, was significantly smaller than free DXR. Furthermore, the tumor accumulation of rHSA/PEG liposomal DXR was significantly larger than that of PEG liposomal DXR. The "therapeutic index", a criterion for therapeutic outcome, for rHSA/PEG fiposornal DXR was significantly higher than PEG liposomal DXR. These results clearly indicate that rHSA-conjugation onto the surface of PEG liposome would be a useful approach to increase the effectiveness and safety of PEG liposomal DXR.

en-copyright= kn-copyright= en-aut-name=YokoeJun-ichi en-aut-sei=Yokoe en-aut-mei=Jun-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SakuragiShiho en-aut-sei=Sakuragi en-aut-mei=Shiho kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YamamotoKayoko en-aut-sei=Yamamoto en-aut-mei=Kayoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TeragakiTakuya en-aut-sei=Teragaki en-aut-mei=Takuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OgawaraKen-ichi en-aut-sei=Ogawara en-aut-mei=Ken-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=HigakiKazutaka en-aut-sei=Higaki en-aut-mei=Kazutaka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KatayamaNaohisa en-aut-sei=Katayama en-aut-mei=Naohisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KaiToshiya en-aut-sei=Kai en-aut-mei=Toshiya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=SatoMakoto en-aut-sei=Sato en-aut-mei=Makoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=KimuraToshikiro en-aut-sei=Kimura en-aut-mei=Toshikiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=Pharmaceutical Research Division, NIPRO Corporation affil-num=2 en-affil= kn-affil=Pharmaceutical Research Division, NIPRO Corporation affil-num=3 en-affil= kn-affil=Pharmaceutical Research Division, NIPRO Corporation affil-num=4 en-affil= kn-affil=Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University affil-num=5 en-affil= kn-affil=Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University affil-num=6 en-affil= kn-affil=bDepartment of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University affil-num=7 en-affil= kn-affil=Pharmaceutical Research Division, NIPRO Corporation affil-num=8 en-affil= kn-affil=Pharmaceutical Research Division, NIPRO Corporation affil-num=9 en-affil= kn-affil=Pharmaceutical Research Division, NIPRO Corporation affil-num=10 en-affil= kn-affil=Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University en-keyword=Recombinant human serum albumin (rHSA) kn-keyword=Recombinant human serum albumin (rHSA) en-keyword=PEG liposome kn-keyword=PEG liposome en-keyword=Doxorubicin kn-keyword=Doxorubicin en-keyword=Tumor-bearing rats kn-keyword=Tumor-bearing rats en-keyword=Passive targeting kn-keyword=Passive targeting END start-ver=1.4 cd-journal=joma no-vol=343 cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080522 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Evaluation of intramuscular lateral distribution profile of topically administered acetaminophen in rats en-subtitle= kn-subtitle= en-abstract= kn-abstract=

To clarify to what extent topically administered drug molecules horizontally permeate into tissues surrounding the administration site, the intramuscular lateral concentration profile of acetaminophen was investigated in vivo using the microdialysis method in rats. When acetaminophen was intramuscularly administered for 6 hr in a pinpoint manner at a constant rate of 3 μg/min, it was clearly detected in the muscle surrounding the administration site, being 17.5 μg/ml when measured at a 2 mm distance from the administration site. The concentration in the muscle was decreased as the distance increased, and those measured at 5 mm and 40 mm were 0.35 μg/ml and 0.09 μg/ml, respectively. In addition, it was shown that the concentration in the muscle at 40 mm reflected the compound’s concentration in plasma, but not the compound’s horizontal permeation from the administration site. With these observations, the intramuscular distribution profile of acetaminophen was numerically characterized according to Fick’s law. As a result, it was revealed that horizontal permeation is the primary process accountable for the increased intramuscular concentration only in the area adjacent to the administration site, and the radius of the adjacent area was calculated to be 5.80 mm for acetaminophen.

en-copyright= kn-copyright= en-aut-name=KurosakiYuji en-aut-sei=Kurosaki en-aut-mei=Yuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TagawaMasahiro en-aut-sei=Tagawa en-aut-mei=Masahiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OmotoAkiho en-aut-sei=Omoto en-aut-mei=Akiho kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SuitoHiroshi en-aut-sei=Suito en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KomoriYukiko en-aut-sei=Komori en-aut-mei=Yukiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KawasakiHiromu en-aut-sei=Kawasaki en-aut-mei=Hiromu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=AibaTetsuya en-aut-sei=Aiba en-aut-mei=Tetsuya kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University affil-num=2 en-affil= kn-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University affil-num=3 en-affil= kn-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University affil-num=4 en-affil= kn-affil=Graduate School of Environmental Sciences, Okayama University affil-num=5 en-affil= kn-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=6 en-affil= kn-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University affil-num=7 en-affil= kn-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University en-keyword=Microdialysis kn-keyword=Microdialysis en-keyword=Intramuscular concentration profile kn-keyword=Intramuscular concentration profile en-keyword=Drug disposition kn-keyword=Drug disposition en-keyword=Acetaminophen kn-keyword=Acetaminophen en-keyword=Pharmacokinetics kn-keyword=Pharmacokinetics en-keyword=Drug delivery kn-keyword=Drug delivery END start-ver=1.4 cd-journal=joma no-vol=44 cd-vols= no-issue=8 article-no= start-page=887 end-page=893 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=200412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Generation of active fragments from human zymogens in the bradykinin-generating cascade by extracellular proteases from Vibrio vulnificus and V. parahaemolyticus en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Vibrio vulnificus is an opportunistic human pathogen causing septicemia, and the infection is characterized by formation of the edematous skin lesions on limbs. This pathogenic species secretes a thermolysin-like metalloprotease as a virulence determinant. The metalloprotease was confirmed to activate human factor XII-plasma kallikrein-kinin cascade that results in liberation of bradykinin, a chemical mediator enhancing the vascular permeability, from high-molecular weight kininogen. Namely, the metalloprotease showed to generate active fragments by cleavage of Arg-Ile, Arg-Val or Gly-Leu peptide bond in human zymogens (plasma prekallikrein and factor XII). In spite of induction of the sufficient vascular permeability-enhancing and edema-forming reaction in the guinea pig model, a serine protease from V. parahaemolyticus, a human pathogen causing primarily watery diarrhea, showed far less ability to activate and to cleave the human zymogens. These results in part may explain why only V. vulnificus often causes serious edematous skin damages in humans.

en-copyright= kn-copyright= en-aut-name=MiyoshiShin-ichi en-aut-sei=Miyoshi en-aut-mei=Shin-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=WatanabeHirofumi en-aut-sei=Watanabe en-aut-mei=Hirofumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KawaseTomoka en-aut-sei=Kawase en-aut-mei=Tomoka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=YamadaHidenori en-aut-sei=Yamada en-aut-mei=Hidenori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ShinodaSumio en-aut-sei=Shinoda en-aut-mei=Sumio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University en-keyword=vibrio vulnificus kn-keyword=vibrio vulnificus en-keyword=vibrio parahaemolyticus kn-keyword=vibrio parahaemolyticus en-keyword=protease kn-keyword=protease en-keyword=factor XII kn-keyword=factor XII en-keyword=plasma prekallikrein kn-keyword=plasma prekallikrein END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=3 article-no= start-page=508 end-page=513 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Induction of cytolytic activity and interferon-gamma production in murine natural killer cells by polymyxins B and E en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Natural killer (NK) cells are the primary effector cells of the innate immune system and have well-established roles in tumor rejection and resistance to viruses, bacteria and certain parasites. There is a need for more specific immune modulators of NK cell activity that tack the wide-ranging side effects of NK cell-stimulatory interleukins. The polycationic antibiotic polymyxin B (PMB) has been shown to have a unique ability to enhance activities of some immune cells, independent of its antibiotic properties. Here we report that both PMB and its analog potymyxin E (PME) markedly enhanced the activity of NK cells enriched from the murine spleen. Maximal activation of NK cell activity was obtained after 24 h of incubation with PMB at a dose of 300 mu g/ml. PMB nonapeptide, one of the two PMB domains, and PME methanesulfonate, the negatively charged derivative of PME, had little effect on NK cell activity. PMB induced interferon (IFN)-gamma and tumor necrosis factor-a production in NK cells. Proliferation of NK cells in vitro was significantly stimulated by being incubated with PMB. Administration of PMB to mice for 7 consecutive days stimulated splenic NK cell activity and increased NK cell populations in the spleen. These results suggest that the polycationic antibiotics PMB and PME may up-regulate innate and adaptive immune responses by induction of NK cell activity and IFN-gamma production.

en-copyright= kn-copyright= en-aut-name=ZhongMing en-aut-sei=Zhong en-aut-mei=Ming kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KadotaYusuke en-aut-sei=Kadota en-aut-mei=Yusuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ShimizuYoshio en-aut-sei=Shimizu en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=GohdaEiichi en-aut-sei=Gohda en-aut-mei=Eiichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Department of Immunochemistry, Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=2 en-affil= kn-affil=Department of Immunochemistry, Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences affil-num=3 en-affil= kn-affil=Bizen Chemical Co., Ltd affil-num=4 en-affil= kn-affil=Department of Immunochemistry, Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences en-keyword=polymyxin B (PMB) kn-keyword=polymyxin B (PMB) en-keyword=polymyxin E (PME) kn-keyword=polymyxin E (PME) en-keyword=NK cells kn-keyword=NK cells en-keyword=IFN-gamma kn-keyword=IFN-gamma END start-ver=1.4 cd-journal=joma no-vol=95 cd-vols= no-issue=23 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200511 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Opacity effect on extreme ultraviolet radiation from laser-produced tin plasmas en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Opacity effects on extreme ultraviolet (EUV) emission from laser-produced tin (Sn) plasma have been experimentally investigated. An absorption spectrum of a uniform Sn plasma generated by thermal x rays has been measured in the EUV range (9-19 nm wavelength) for the first time. Experimental results indicate that control of the optical depth of the laser-produced Sn plasma is essential for obtaining high conversion to 13.5 nm-wavelength EUV radiation; 1.8% of the conversion efficiency was attained with the use of 2.2 ns laser pulses.

en-copyright= kn-copyright= en-aut-name=FujiokaShinsuke en-aut-sei=Fujioka en-aut-mei=Shinsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NishimuraHiroaki en-aut-sei=Nishimura en-aut-mei=Hiroaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NishiharaKatsunobu en-aut-sei=Nishihara en-aut-mei=Katsunobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SasakiAkira en-aut-sei=Sasaki en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=SunaharaAtsushi en-aut-sei=Sunahara en-aut-mei=Atsushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OkunoTomoharu en-aut-sei=Okuno en-aut-mei=Tomoharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=UedaNobuyoshi en-aut-sei=Ueda en-aut-mei=Nobuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=AndoTsuyoshi en-aut-sei=Ando en-aut-mei=Tsuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=TaoYezheng en-aut-sei=Tao en-aut-mei=Yezheng kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=ShimadaYoshinori en-aut-sei=Shimada en-aut-mei=Yoshinori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=HashimotoKazuhisa en-aut-sei=Hashimoto en-aut-mei=Kazuhisa kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=YamauraMichiteru en-aut-sei=Yamaura en-aut-mei=Michiteru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=ShigemoriKeisuke en-aut-sei=Shigemori en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=NakaiMitsuo en-aut-sei=Nakai en-aut-mei=Mitsuo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=NagaiKeiji en-aut-sei=Nagai en-aut-mei=Keiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=NorimatsuTakayoshi en-aut-sei=Norimatsu en-aut-mei=Takayoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= en-aut-name=NishikawaTakeshi en-aut-sei=Nishikawa en-aut-mei=Takeshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=17 ORCID= en-aut-name=MiyanagaNoriaki en-aut-sei=Miyanaga en-aut-mei=Noriaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=18 ORCID= en-aut-name=IzawaYasukazu en-aut-sei=Izawa en-aut-mei=Yasukazu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=19 ORCID= en-aut-name=MimaKunioki en-aut-sei=Mima en-aut-mei=Kunioki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=20 ORCID= affil-num=1 en-affil= kn-affil=Osaka University affil-num=2 en-affil= kn-affil=Osaka University affil-num=3 en-affil= kn-affil=Osaka University affil-num=4 en-affil= kn-affil=Advanced Photon Research Center affil-num=5 en-affil= kn-affil=Institute for Laser Technology affil-num=6 en-affil= kn-affil=Osaka University affil-num=7 en-affil= kn-affil=Osaka University affil-num=8 en-affil= kn-affil=Osaka University affil-num=9 en-affil= kn-affil=Osaka University affil-num=10 en-affil= kn-affil=Institute for Laser Technology affil-num=11 en-affil= kn-affil=Institute for Laser Technology affil-num=12 en-affil= kn-affil=Institute for Laser Technology affil-num=13 en-affil= kn-affil=Osaka University affil-num=14 en-affil= kn-affil=Osaka University affil-num=15 en-affil= kn-affil=Osaka University affil-num=16 en-affil= kn-affil=Osaka University affil-num=17 en-affil= kn-affil=Okayama University affil-num=18 en-affil= kn-affil=Osaka University affil-num=19 en-affil= kn-affil=Osaka University affil-num=20 en-affil= kn-affil=Osaka University en-keyword=emission kn-keyword=emission en-keyword=targets kn-keyword=targets en-keyword=lithography kn-keyword=lithography en-keyword=fusion kn-keyword=fusion END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=14 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20054 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Observation of the acceleration of a single bunch by using the induction device in the kek proton synchrotron en-subtitle= kn-subtitle= en-abstract= kn-abstract=

A single rf bunch in the KEK proton synchrotron was accelerated with an induction acceleration method from the injection energy of 500 MeV to 5 GeV.

en-copyright= kn-copyright= en-aut-name=TakayamaKen en-aut-sei=Takayama en-aut-mei=Ken kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KosekiKunio en-aut-sei=Koseki en-aut-mei=Kunio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TorikaiKota en-aut-sei=Torikai en-aut-mei=Kota kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TokuchiAkira en-aut-sei=Tokuchi en-aut-mei=Akira kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=NakamuraEiji en-aut-sei=Nakamura en-aut-mei=Eiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=ArakidaYoshio en-aut-sei=Arakida en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=ShimosakiYoshito en-aut-sei=Shimosaki en-aut-mei=Yoshito kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=WakeMasayoshi en-aut-sei=Wake en-aut-mei=Masayoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=KounoTadaaki en-aut-sei=Kouno en-aut-mei=Tadaaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=HoriokaKazuhiko en-aut-sei=Horioka en-aut-mei=Kazuhiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=IgarashiSusumu en-aut-sei=Igarashi en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=IwashitaTaiki en-aut-sei=Iwashita en-aut-mei=Taiki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=KawasakiAtsushi en-aut-sei=Kawasaki en-aut-mei=Atsushi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=KishiroJun-ichi en-aut-sei=Kishiro en-aut-mei=Jun-ichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= en-aut-name=SakudaMakoto en-aut-sei=Sakuda en-aut-mei=Makoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=15 ORCID= en-aut-name=SatoHikaru en-aut-sei=Sato en-aut-mei=Hikaru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=16 ORCID= en-aut-name=ShihoMakoto en-aut-sei=Shiho en-aut-mei=Makoto kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=17 ORCID= en-aut-name=ShirakataMasashi en-aut-sei=Shirakata en-aut-mei=Masashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=18 ORCID= en-aut-name=SuenoTsuyoshi en-aut-sei=Sueno en-aut-mei=Tsuyoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=19 ORCID= en-aut-name=ToyamaTakeshi en-aut-sei=Toyama en-aut-mei=Takeshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=20 ORCID= en-aut-name=WatanabeMasao en-aut-sei=Watanabe en-aut-mei=Masao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=21 ORCID= en-aut-name=YamaneIsao en-aut-sei=Yamane en-aut-mei=Isao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=22 ORCID= affil-num=1 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=2 en-affil= kn-affil=Graduate University for Advanced Studies affil-num=3 en-affil= kn-affil=Kyushu University affil-num=4 en-affil= kn-affil=Nichicon Corporation affil-num=5 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=6 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=7 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=8 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=9 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=10 en-affil= kn-affil=Tokyo Institute of Technology affil-num=11 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=12 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=13 en-affil= kn-affil=Nichicon Corporation affil-num=14 en-affil= kn-affil=Japan Atomic Energy Research Institute affil-num=15 en-affil= kn-affil=Okayama University affil-num=16 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=17 en-affil= kn-affil=Japan Atomic Energy Research Institute affil-num=18 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=19 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=20 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK affil-num=21 en-affil= kn-affil=Japan Atomic Energy Research Institute affil-num=22 en-affil= kn-affil=High Energy Accelerator Research Organization, KEK END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=22 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=200512 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Electronic structure and spontaneous internal field around nonmagnetic impurities in spin-triplet chiral p-wave superconductors en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The electronic structure around an impurity in spin-triplet p-wave superconductors is studied by the Bogoliubov-de Gennes theory on a tight-binding model, where we have chosen sin p(x)+i sin p(y)-wave or sin(p(x)+p(y))+i sin(-p(x)+p(y))-wave states, which are considered to be candidates for the pairing state in Sr2RuO4. We calculate the spontaneous current and the local density of states around the impurity and discuss the difference between the two types of pairing. We propose that it is possible to discriminate the two pairing states by studying the spatial dependence of the magnetic field around a pair of impurities.

en-copyright= kn-copyright= en-aut-name=TakigawaMitsuaki en-aut-sei=Takigawa en-aut-mei=Mitsuaki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=IchiokaMasanori en-aut-sei=Ichioka en-aut-mei=Masanori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KurokiKazuhiko en-aut-sei=Kuroki en-aut-mei=Kazuhiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TanakaYukio en-aut-sei=Tanaka en-aut-mei=Yukio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Hokkaido University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=University of Electro-Communications affil-num=4 en-affil= kn-affil=Nagoya University en-keyword=unconventional superconductors kn-keyword=unconventional superconductors en-keyword=sr2ru04 kn-keyword=sr2ru04 en-keyword=states kn-keyword=states en-keyword=scattering kn-keyword=scattering en-keyword=junction kn-keyword=junction en-keyword=shift kn-keyword=shift en-keyword=phase kn-keyword=phase en-keyword=model kn-keyword=model en-keyword=gap kn-keyword=gap END start-ver=1.4 cd-journal=joma no-vol=127 cd-vols= no-issue=6 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070814 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Line and boundary tensions on approach to the wetting transition en-subtitle= kn-subtitle= en-abstract= kn-abstract=A mean-field density-functional model often used in the past in the study of line and boundary tensions at wetting and prewetting transitions is reanalyzed by extensive numerical calculations, approaching the wetting transition much more closely than had previously been possible. The results are what are now believed to be definitive for the model. They include strong numerical evidence for the presence of the logarithmic factors predicted by theory both in the mode of approach of the prewetting line to the triple-point line at the point of the first-order wetting transition and in the line tension itself on approach to that point. It is also demonstrated with convincing numerical precision that the boundary tension on the prewetting line and the line tension on the triple-point line have a common limiting value at the wetting transition, again as predicted by theory. As a by product of the calculations, in the model's symmetric three-phase state, far from wetting, it is found that certain properties of the model's line tension and densities are almost surely given by simple numbers arising from the symmetries, but proving that these are exact for the model remains a challenge to analytical theory. en-copyright= kn-copyright= en-aut-name=KogaKenichiro en-aut-sei=Koga en-aut-mei=Kenichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=WidomB. en-aut-sei=Widom en-aut-mei=B. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Baker Laboratory, Cornell University en-keyword=SURFACE PHASES kn-keyword=SURFACE PHASES en-keyword=FLUID PHASES kn-keyword=FLUID PHASES en-keyword=SUBSTRATE kn-keyword=SUBSTRATE en-keyword=ADSORPTION kn-keyword=ADSORPTION en-keyword=INTERFACE kn-keyword=INTERFACE en-keyword=CONTACT kn-keyword=CONTACT en-keyword=MODEL kn-keyword=MODEL en-keyword=ICE kn-keyword=ICE END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=6 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20052 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Anisotropic diamagnetic response in type-II superconductors with gap and fermi-surface anisotropies en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The effects of anisotropic gap structures on a diamagnetic response are investigated in order to demonstrate that the field-angle-resolved magnetization [M-L (chi)] measurement can be used as a spectroscopic method to detect gap structures. Our microscopic calculation based on the quasiclassical Eilenberger formalism reveals that M-L (chi) in a superconductor with a fourfold gap displays a fourfold oscillation reflecting the gap and Fermi-surface anisotropies, and the sign of this oscillation changes at a field between H-c1 and H-c2. As a prototype of unconventional superconductors, magnetization data for borocarbides are also discussed.

en-copyright= kn-copyright= en-aut-name=AdachiH en-aut-sei=Adachi en-aut-mei=H kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MiranovicP en-aut-sei=Miranovic en-aut-mei=P kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IchiokaM en-aut-sei=Ichioka en-aut-mei=M kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=MachidaK en-aut-sei=Machida en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=University of Montenegro affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University en-keyword=ginzburg-landau equations kn-keyword=ginzburg-landau equations en-keyword=density-of-states kn-keyword=density-of-states en-keyword=virial-theorem kn-keyword=virial-theorem en-keyword=magnetization kn-keyword=magnetization en-keyword=dependence kn-keyword=dependence en-keyword=symmetry kn-keyword=symmetry en-keyword=luni2b2c kn-keyword=luni2b2c en-keyword=yni2b2c kn-keyword=yni2b2c END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=22 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20056 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Metallic phase in the metal-intercalated higher fullerene Rb8.8(7)C84 en-subtitle= kn-subtitle= en-abstract= kn-abstract=

A new material of higher fullerene, RbxC84, was synthesized by intercalating Rb metal into C-84 crystals. The RbxC(84) crystals showed a simple cubic (sc) structure with lattice constant, a, of 16.82 (2) angstrom at 6.5 K, and 16.87 (2) angstrom at 295 K. The Rietveld refinements were achieved with the space group, Pa (3) over bar, based on a model that the C-2 axis of D2d-C84 aligned along [111]. The sample composition was determined to be Rb-8.8(7) C-84. The ESR spectrum at 303 K was composed of a broad peak with peak-to-peak linewidth Delta H-pp of 220 G, and a narrow peak with Delta H-pp of 24 G. Temperature dependence of the broad peak clearly showed a metallic behavior. The metallic behavior was discussed based on a theoretical calculation. This finding of new metallic phase in a higher fullerene is the first step for a development of new types of fullerene materials with novel physical properties such as superconductivity.

en-copyright= kn-copyright= en-aut-name=RikiishiYoshie en-aut-sei=Rikiishi en-aut-mei=Yoshie kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KashinoYoko en-aut-sei=Kashino en-aut-mei=Yoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KusaiHaruka en-aut-sei=Kusai en-aut-mei=Haruka kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=TakabayashiYasuhiro en-aut-sei=Takabayashi en-aut-mei=Yasuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KuwaharaEiji en-aut-sei=Kuwahara en-aut-mei=Eiji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KubozonoYoshihiro en-aut-sei=Kubozono en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KambeTakashi en-aut-sei=Kambe en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=TakenobuTaishi en-aut-sei=Takenobu en-aut-mei=Taishi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=IwasaYoshihiro en-aut-sei=Iwasa en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=MizorogiNaomi en-aut-sei=Mizorogi en-aut-mei=Naomi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=NagaseShigeru en-aut-sei=Nagase en-aut-mei=Shigeru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=OkadaSusumu en-aut-sei=Okada en-aut-mei=Susumu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=3 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=4 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=5 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=6 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=7 en-affil= kn-affil=Department of Physics, Okayama University affil-num=8 en-affil= kn-affil=CREST, Japan Science and Technology Agency affil-num=9 en-affil= kn-affil=CREST, Japan Science and Technology Agency affil-num=10 en-affil= kn-affil=Institute for Molecular Science affil-num=11 en-affil= kn-affil=Institute for Molecular Science affil-num=12 en-affil= kn-affil=Institute of Physics and Center for Computational Science, University of Tsukuba END start-ver=1.4 cd-journal=joma no-vol=61 cd-vols= no-issue=2 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20001 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Annealing effects on the magnetic and structural properties of single-crystal TDAE-C-60 en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Annealing effects on the magnetic and structural properties of single-crystal TDAE-C-60 are investigated. When a crystal is well-annealed at 350 K, ferromagnetic ordering takes place below 16 K, though no magnetic phase transition is shown in as-grown crystal. The saturated magnetization was obtained to be 0.9+/-0.1 mu(B) per C-60. It was first found that the well-annealed crystal shows a structural phase transition around 180 K, probably associated with the orientational ordering of C-60 molecules. On the other hand, the as-grown crystal undergoes no structural phase transition at least down to 30 K while the motion of C-60 molecules is restricted below around 150 K. The possible relation between the low-temperature structure and the magnetic ordering is discussed.

en-copyright= kn-copyright= en-aut-name=KambeTakashi en-aut-sei=Kambe en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NogamiYoshio en-aut-sei=Nogami en-aut-mei=Yoshio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OshimaKokichi en-aut-sei=Oshima en-aut-mei=Kokichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Physics, Faculty of Science, Okayama University affil-num=2 en-affil= kn-affil=Department of Physics, Faculty of Science, Okayama University affil-num=3 en-affil= kn-affil=Department of Physics, Faculty of Science, Okayama University END start-ver=1.4 cd-journal=joma no-vol=401 cd-vols= no-issue= article-no= start-page=218 end-page=221 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080629 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Formation of low-resistivity region in p-Si substrate of SiGe/Si episystem by remote-hydrogen plasma treatment en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We have studied effects of hydrogen treatment on the resistivity profile of the SiGe/Si episystem by spreading resistance (SR) method. In this paper, we present experimental findings that hydrogen treatment reduces the resistivity at a specific part in the Si substrate region. This position was confirmed to be under the interface between SiGe and Si that emerged on the bevel surface during hydrogen treatment. We investigated the depth of resistivity-reduced regions which was formed by various hydrogenating conditions and found that the region was extended to the same depth as the penetration depth of hydrogen. We concluded that the low-resistivity region was formed under the influence of hydrogen introduced from bevel surface. We attributed this resistivity reduction to formation of some defects which originally existed at the interface and diffused into Si substrate with hydrogen.

en-copyright= kn-copyright= en-aut-name=YamashitaYoshifumi en-aut-sei=Yamashita en-aut-mei=Yoshifumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SakamotoYoshifumi en-aut-sei=Sakamoto en-aut-mei=Yoshifumi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KamiuraYoichi en-aut-sei=Kamiura en-aut-mei=Yoichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=IshiyamaTakeshi en-aut-sei=Ishiyama en-aut-mei=Takeshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Okayama University affil-num=4 en-affil= kn-affil=The Graduate School of Natural Science and Technology, Okayama University en-keyword=SiGe/Si kn-keyword=SiGe/Si en-keyword=Hydroge. Resistivity reduction kn-keyword=Hydroge. Resistivity reduction en-keyword=Interface kn-keyword=Interface END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=6 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20062 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Resonant inelastic x-ray scattering at the oxygen k resonance of nio:nonlocal charge transfer and double-singlet excitations en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We report high-resolution polarization-dependent resonant inelastic x-ray scattering (RIXS) at the O K resonance of NiO showing a rich excitation spectrum. We perform multisite Ni6O19 cluster model calculations, revealing that solid state effects are substantial. We identify a nonlocal charge transfer excitation at 4-5 eV and double-singlet creation at 1.75 eV, both exhibiting significant scattering geometry dependence. Apart from an intense band of local charge transfer excitations (above 5 eV) also dd excitations at 1 eV are observed. Finally, we point out that O K RIXS of correlated metal oxides allows a quantitative and consistent determination of the charge transfer energy Delta and the Hund coupling energy J(H).

en-copyright= kn-copyright= en-aut-name=DudaL C en-aut-sei=Duda en-aut-mei=L C kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SchmittT en-aut-sei=Schmitt en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=MangnusonM en-aut-sei=Mangnuson en-aut-mei=M kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ForsbergJ en-aut-sei=Forsberg en-aut-mei=J kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=OlssonA en-aut-sei=Olsson en-aut-mei=A kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NordgrenJ. en-aut-sei=Nordgren en-aut-mei=J. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=OkadaK en-aut-sei=Okada en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=KotaniA en-aut-sei=Kotani en-aut-mei=A kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=Uppsala University affil-num=2 en-affil= kn-affil=Uppsala University affil-num=3 en-affil= kn-affil=Uppsala University affil-num=4 en-affil= kn-affil=Uppsala University affil-num=5 en-affil= kn-affil=Uppsala University affil-num=6 en-affil= kn-affil=Uppsala University affil-num=7 en-affil= kn-affil=Okayama University affil-num=8 en-affil= kn-affil=High Energy Accelerator Research Organization en-keyword=transition-meal compounds kn-keyword=transition-meal compounds en-keyword=electronic-structure kn-keyword=electronic-structure en-keyword=raman-scattering kn-keyword=raman-scattering en-keyword=emission-spectroscopy kn-keyword=emission-spectroscopy en-keyword=spectra kn-keyword=spectra en-keyword=absorption kn-keyword=absorption en-keyword=coo kn-keyword=coo END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=17 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20055 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Structural differences in two polymorphs of tetra-kis-(dimethylamino)-ethylene-C-60: An x-ray diffraction study en-subtitle= kn-subtitle= en-abstract= kn-abstract=

A type of low-temperature structure for ferromagnetic alpha-tetra-kis (dimethylamino) -ethylene (TDAE)-C-60 is proposed on the basis of low-temperature x-ray analysis. We observed that intense superlattice reflections with odd indices successively appeared below T-s = 170 K. The space group symmetry of the low-temperature phase is determined to be P2(1)/n. Two inequivalent C-60 sites exist in the low-temperature phase, which are indispensable to the orbital ordering model Of C-60. The contact configuration for the neighboring C(60)s along the stacking c direction is uniquely determined. The double bond between the hexagons faces the neighboring pentagon. We found that the surrounding TDAE molecules shift along the c axis (similar to 0.07 angstrom) and that these shifts correlate perfectly to the alignment of C-60. This result indicates that the steric effect betwee n C-60 and TDAE molecules plays an important role in the orientational ordering Of C-60, On the other hand, in the alpha' phase, no structural phase transition was observed below 30 K. This indicates that all the C(60)s are crystallographically equivalent. Structural differences separate the magnetic peculiarities of the two polymorphs in TDAE-C-60.

en-copyright= kn-copyright= en-aut-name=FujiwaraMotoyasu en-aut-sei=Fujiwara en-aut-mei=Motoyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KambeTakashi en-aut-sei=Kambe en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=OshimaKokichi en-aut-sei=Oshima en-aut-mei=Kokichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University en-keyword=Physics kn-keyword=Physics en-keyword=Condensed Matter kn-keyword=Condensed Matter END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=1 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20051 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Competing spin phases in geometrically frustrated magnetic molecules en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We identify a class of zero-dimensional classical and quantum Heisenberg spin systems exhibiting anomalous behavior in an external magnetic field B similar to that found for the geometrically frustrated kagome lattice of classical spins. Our calculations for the isotropic Heisenberg model show the emergence of a pronounced minimum in the differential susceptibility dM/dB at B-sat/3 as the temperature T is raised from 0 K for structures based on corner-sharing triangles, specifically the octahedron, cuboctahedron, and icosidodecahedron. As the first experimental evidence we note that the giant Keplerate magnetic molecule {Mo72Fe30} (Fe3+ ions on the 30 vertices of an icosidodecahedron) exhibits this behavior. For low T when Bapproximate toB(sat)/3 two competing families of spin configurations exist of which one behaves magnetically "stiff" leading to a reduction of dM/dB.

en-copyright= kn-copyright= en-aut-name=SchroderChristian en-aut-sei=Schroder en-aut-mei=Christian kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NojiriHiroyuki en-aut-sei=Nojiri en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=SchnackJurgen en-aut-sei=Schnack en-aut-mei=Jurgen kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HagePeter en-aut-sei=Hage en-aut-mei=Peter kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=LubanMarshall en-aut-sei=Luban en-aut-mei=Marshall kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KogerlerPaul en-aut-sei=Kogerler en-aut-mei=Paul kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=University of Applied Sciences Bielefeld affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Universitat Osnabruck affil-num=4 en-affil= kn-affil=Universitat Osnabruck affil-num=5 en-affil= kn-affil=Iowa State University affil-num=6 en-affil= kn-affil=Iowa State University en-keyword=antiferromagnet kn-keyword=antiferromagnet en-keyword=field kn-keyword=field en-keyword=lattice kn-keyword=lattice en-keyword=spheres kn-keyword=spheres en-keyword=state kn-keyword=state END start-ver=1.4 cd-journal=joma no-vol=124 cd-vols= no-issue=13 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060407 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Close-packed structures and phase diagram of soft spheres in cylindrical pores en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is shown for a model system consisting of spherical particles confined in cylindrical pores that the first ten close-packed phases are in one-to-one correspondence with the first ten ways of folding a triangular lattice, each being characterized by a roll-up vector like the single-walled carbon nanotube. Phase diagrams in pressure-diameter and temperature-diameter planes are obtained by inherent-structure calculation and molecular dynamics simulation. The phase boundaries dividing two adjacent phases are infinitely sharp in the low-temperature limit but are blurred as temperature is increased. Existence of such phase boundaries explains rich, diameter-sensitive phase behavior unique for cylindrically confined systems. en-copyright= kn-copyright= en-aut-name=KogaKenichiro en-aut-sei=Koga en-aut-mei=Kenichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TanakaHideki en-aut-sei=Tanaka en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University en-keyword=WALLED CARBON NANOTUBES kn-keyword=WALLED CARBON NANOTUBES en-keyword=NANOCAPILLARITY kn-keyword=NANOCAPILLARITY en-keyword=MICROTUBULES kn-keyword=MICROTUBULES en-keyword=CAPILLARITY kn-keyword=CAPILLARITY en-keyword=CRYSTALS kn-keyword=CRYSTALS END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=10 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20049 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Structure and magnetic properties of the single-molecule magnet [Mn11CrO12(O2CCH3)(16)(H2O)(4)]center dot 2CH(3)COOH center dot 4H(2)O: magnetization manipulation and dipolar-biased tunneling in a Mn11Cr/Mn-12 mixed crystal en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The structural and magnetic properties of the single-molecule magnet [Mn11CrO12(O2CCH3)(16)(H2O)(4)].2CH(3)COOH.4H(2)O (Mn11Cr) are studied through the analysis of a Mn11Cr/Mn-12 (approximate to1:1) mixed crystal, where Mn-12 is [Mn12O12(O2CCH3)(16)(H2O)(4)].2CH(3)COOH.4H(2)O. X-ray absorption spectra reveal that the Cr ion in Mn11Cr is in the +3 valence state and occupies a specific Mn3+ site in the Mn-12 skeleton. High-frequency electron paramagnetic resonance (EPR) spectra are well explained by assuming that Mn11Cr is in a ground spin-state of S=19/2 with nearly the same EPR parameter set as for Mn-12. The lower spin quantum number results in lower barrier height (56.8 K) compared to Mn-12. The magnetization curves indicate a coercive field of 0.95 T for Mn11Cr at 1.8 K, nearly half that for Mn-12. Quantum tunneling of magnetization (QTM) in Mn11Cr is observed below the blocking temperature T-B, with the same field interval as for Mn-12. The magnetization of Mn11Cr and Mn-12 in the mixed crystal can be independently manipulated by utilizing the difference between their coercive fields. The resonance fields of QTM in Mn11Cr are significantly affected by the magnetization direction of Mn-12, suggesting the effect of dipolar-biased tunneling.

en-copyright= kn-copyright= en-aut-name=HachisukaHidekazu en-aut-sei=Hachisuka en-aut-mei=Hidekazu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=AwagaKunio en-aut-sei=Awaga en-aut-mei=Kunio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=YokoyamaToshihiko en-aut-sei=Yokoyama en-aut-mei=Toshihiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KuboTakeji en-aut-sei=Kubo en-aut-mei=Takeji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=GotoTakao en-aut-sei=Goto en-aut-mei=Takao kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NojiriHiroyuki en-aut-sei=Nojiri en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Nagoya University affil-num=2 en-affil= kn-affil=Nagoya University affil-num=3 en-affil= kn-affil=Institute for Molecular Sciences affil-num=4 en-affil= kn-affil=Nara University of Education affil-num=5 en-affil= kn-affil=Graduate School of Human and Environmental Studies affil-num=6 en-affil= kn-affil=Okayama University en-keyword=high-spin molecules kn-keyword=high-spin molecules en-keyword=jahn-teller isomerism kn-keyword=jahn-teller isomerism en-keyword=ground-state kn-keyword=ground-state en-keyword=mn-12 kn-keyword=mn-12 en-keyword=complexes kn-keyword=complexes en-keyword=relaxation kn-keyword=relaxation en-keyword=susceptibility kn-keyword=susceptibility en-keyword=mn12012(02cr)(16)(H20)(4) kn-keyword=mn12012(02cr)(16)(H20)(4) en-keyword=mn12012(02CR)16(h20)4 kn-keyword=mn12012(02CR)16(h20)4 en-keyword=cluster kn-keyword=cluster en-keyword=s=9 kn-keyword=s=9 END start-ver=1.4 cd-journal=joma no-vol=59 cd-vols= no-issue=23 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19996 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Metal-insulator transition at 50 K in Na2C60 en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Temperature dependence of electron spin resonance in Na2C60 was studied in a temperature range from 2 to 350 K. It was shown that Na2C60 was metallic above 50 K and had a metal-insulator transition at 50 K. The center frequency for the Hg(2) Raman mode in Na2C60 at 298 K was close to those in the metallic Rb3C60, K3C60, and Cs3C60, while the linewidth was close to that in the metallic but nonsuperconducting Cs3C60. The Hg(2) mode showed a large blueshift and narrowing at 50 K. The center frequency and the linewidth in the low-temperature region from 50 K were almost the same as those in the insulating C-60 and Rb6C60, which showed the metal-insulator transition at 50 K in Na2C60. The origin of this metal-insulator transition was discussed in terms of the electron-phonon interaction (Jahn-Teller effect) and the electron-electron interaction (Mott-Hubbard picture). [S0163-1829(99)04123-5].

en-copyright= kn-copyright= en-aut-name=KubozonoY. en-aut-sei=Kubozono en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakabayashiY. en-aut-sei=Takabayashi en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FujikiS. en-aut-sei=Fujiki en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KashinoS. en-aut-sei=Kashino en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KambeT. en-aut-sei=Kambe en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=IwasaY. en-aut-sei=Iwasa en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=EmuraS. en-aut-sei=Emura en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=3 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=4 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=5 en-affil= kn-affil=Department of Physics, Okayama University affil-num=6 en-affil= kn-affil=Japan Advanced Institute of Science and Technology affil-num=7 en-affil= kn-affil=ISIR, Osaka University END start-ver=1.4 cd-journal=joma no-vol=63 cd-vols= no-issue=4 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20011 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Structure and physical properties of Na4C60 under ambient and high pressures en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The structure and physical properties of two-dimensional polymeric Na4C60 (body-centered monoclinic, space group I2/m) are studied in a wide temperature region from 12 to 300 K at 1 bar, and in a pressure region up to 53 kbar at 300 K. The temperature dependence of lattice constants suggests a structural anomaly below 100 K where the variation of spin susceptibility is observed from electron spin resonance. The thermal expansion of the unit-cell volume V is smaller than that of monomeric Rb3C60 and K3C60. The compressibility of c is larger than that of a and b, which can be well explained by the repulsion between Na ions. The compressibility of the center-to-center distance in the (10(1) over bar) plane is similar to1/3 times smaller that that in the (101) plane, which can be well explained by the formation of the polymer chains. Further, a possibility of a three-dimensional polymerization is discussed on the basis of the pressure dependence of C-60. . .C-60 distances.

en-copyright= kn-copyright= en-aut-name=KubozonoY. en-aut-sei=Kubozono en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TakabayashiY. en-aut-sei=Takabayashi en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KambeT. en-aut-sei=Kambe en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=FujikiS. en-aut-sei=Fujiki en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=KashinoS. en-aut-sei=Kashino en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=EmuraS. en-aut-sei=Emura en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=3 en-affil= kn-affil=Department of Physics, Okayama University affil-num=4 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=5 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=6 en-affil= kn-affil=ISIR, Osaka University END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=6 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20058 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Carbon-substitution dependent multiple superconducting gap of MgB2: A sub-meV resolution photoemission study en-subtitle= kn-subtitle= en-abstract= kn-abstract=

"Sub-meV" resolution photoemission spectroscopy was used to study carbon-substitution dependence of the multiple superconducting gap of Mg(B1-xCx)(2). Two features corresponding to sigma and pi gaps are clearly observed in the raw spectra up to carbon concentration x=0.075. The observed x dependence of the two gaps shows a qualitatively different behavior: the sigma gap is proportional to T-c while the pi gap shows negligible change. Doping as well as temperature dependence can be explained within the two-band mean-field theory. Implications from the present study are discussed.

en-copyright= kn-copyright= en-aut-name=TsudaS en-aut-sei=Tsuda en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=YokoyaT en-aut-sei=Yokoya en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KissT en-aut-sei=Kiss en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=ShimojimaT en-aut-sei=Shimojima en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ShinS en-aut-sei=Shin en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TogashiT en-aut-sei=Togashi en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=WatanabeS en-aut-sei=Watanabe en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=ZhangC en-aut-sei=Zhang en-aut-mei=C kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=ChenC T en-aut-sei=Chen en-aut-mei=C T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= en-aut-name=LeeS en-aut-sei=Lee en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=10 ORCID= en-aut-name=UchiyamaH en-aut-sei=Uchiyama en-aut-mei=H kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=11 ORCID= en-aut-name=TajimaS en-aut-sei=Tajima en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=12 ORCID= en-aut-name=NakaiN en-aut-sei=Nakai en-aut-mei=N kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=13 ORCID= en-aut-name=MachidaK en-aut-sei=Machida en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=University of Tokyo affil-num=2 en-affil= kn-affil=University of Tokyo affil-num=3 en-affil= kn-affil=Institute of Physical and Chemical Research affil-num=4 en-affil= kn-affil=University of Tokyo affil-num=5 en-affil= kn-affil=University of Tokyo affil-num=6 en-affil= kn-affil=Institute of Physical and Chemical Research affil-num=7 en-affil= kn-affil=University of Tokyo affil-num=8 en-affil= kn-affil=Beijing Center for Crystal R&D affil-num=9 en-affil= kn-affil=Beijing Center for Crystal R&D affil-num=10 en-affil= kn-affil=International Superconductivity Technology Center affil-num=11 en-affil= kn-affil=International Superconductivity Technology Center affil-num=12 en-affil= kn-affil=International Superconductivity Technology Center affil-num=13 en-affil= kn-affil=Kyoto University affil-num=14 en-affil= kn-affil=Okayama University en-keyword=magnesium diboride kn-keyword=magnesium diboride en-keyword=single-crystals kn-keyword=single-crystals en-keyword=origin kn-keyword=origin en-keyword=boron kn-keyword=boron END start-ver=1.4 cd-journal=joma no-vol=65 cd-vols= no-issue=23 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20026 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Structure and physical properties of Cs3+alpha C60 (alpha=0.0-1.0) under ambient and high pressures en-subtitle= kn-subtitle= en-abstract= kn-abstract=

The intermediate phases Cs3+alphaC60 (alpha=0.0-1.0), have been prepared, and their structure and physical properties are studied by x-ray powder diffraction, Raman, ESR, electric conductivity, and ac susceptibility measurements under ambient and high pressures. The x-ray powder diffraction pattern of Cs3+alphaC60 (alpha=0.0-1.0) can be indexed as a mixture of the body-centered-orthorhombic (bco) and cubic (A15) phases. The A15 phase diminishes above 30 kbar. The broad ESR peak due to the conduction electron (c-ESR) is observed only for the phases around alpha=0.0 in Cs3+alphaC60. The resistivity of the Cs3+alphaC60 (alphanot equal0) sample follows the granular metal theory and/or Sheng model even in the sample exhibiting a broad ESR peak. No superconducting transition is observed up to 10.6 kbar in Cs3+alphaC60 (alphanot equal0). These results present that bco phase of Cs3+alphaC60 (alpha=0) is a final candidate for a pressure-induced superconductor.

en-copyright= kn-copyright= en-aut-name=FujikiS. en-aut-sei=Fujiki en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KubozonoY. en-aut-sei=Kubozono en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KobayashiM. en-aut-sei=Kobayashi en-aut-mei=M. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KambeT. en-aut-sei=Kambe en-aut-mei=T. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=RikiishiY. en-aut-sei=Rikiishi en-aut-mei=Y. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=KashinoS. en-aut-sei=Kashino en-aut-mei=S. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=IshiiK. en-aut-sei=Ishii en-aut-mei=K. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=SuematsuH. en-aut-sei=Suematsu en-aut-mei=H. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=FujiwaraA. en-aut-sei=Fujiwara en-aut-mei=A. kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=2 en-affil= kn-affil=Department of Vacuum UV Photoscience, Institute for Molecular Science affil-num=3 en-affil= kn-affil=Department of Materials Science, Himeji Institute of Technology affil-num=4 en-affil= kn-affil=Department of Physics, Okayama University affil-num=5 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=6 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=7 en-affil= kn-affil=Department of Physics, The University of Tokyo affil-num=8 en-affil= kn-affil=Department of Physics, The University of Tokyo affil-num=9 en-affil= kn-affil=Japan Advanced Institute of Science and Technology END start-ver=1.4 cd-journal=joma no-vol=122 cd-vols= no-issue=10 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050308 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Phase diagram of water between hydrophobic surfaces en-subtitle= kn-subtitle= en-abstract= kn-abstract=Molecular dynamics simulations demonstrate that there are at least two classes of quasi-two-dimensional solid water into which liquid water confined between hydrophobic surfaces freezes spontaneously and whose hydrogen-bond networks are as fully connected as those of bulk ice. One of them is the monolayer ice and the other is the bilayer solid which takes either a crystalline or an amorphous form. Here we present the phase transformations among liquid, bilayer amorphous (or crystalline) ice, and monolayer ice phases at various thermodynamic conditions, then determine curves of melting, freezing, and solid-solid structural change on the isostress planes where temperature and intersurface distance are variable, and finally we propose a phase diagram of the confined water in the temperature-pressure-distance space. en-copyright= kn-copyright= en-aut-name=KogaKenichiro en-aut-sei=Koga en-aut-mei=Kenichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TanakaHideki en-aut-sei=Tanaka en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Okayama University en-keyword=MOLECULAR-DYNAMICS SIMULATION kn-keyword=MOLECULAR-DYNAMICS SIMULATION en-keyword=CONFINED WATER kn-keyword=CONFINED WATER en-keyword=LIQUID WATER kn-keyword=LIQUID WATER en-keyword=SOLVATION FORCES; CARBON NANOTUBES kn-keyword=SOLVATION FORCES; CARBON NANOTUBES en-keyword=BILAYER ICE kn-keyword=BILAYER ICE en-keyword=EQUILIBRIA kn-keyword=EQUILIBRIA en-keyword=TRANSITION kn-keyword=TRANSITION en-keyword=WALLS kn-keyword=WALLS en-keyword=INTERFACE kn-keyword=INTERFACE END start-ver=1.4 cd-journal=joma no-vol=127 cd-vols= no-issue=8 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070828 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Phase equilibria and interfacial tension of fluids confined in narrow pores en-subtitle= kn-subtitle= en-abstract= kn-abstract=Correlation between phase behaviors of a Lennard-Jones fluid in and outside a pore is examined over wide thermodynamic conditions by grand canonical Monte Carlo simulations. A pressure tensor component of the confined fluid, a variable controllable in simulation but usually uncontrollable in experiment, is related with the pressure of a bulk homogeneous system in equilibrium with the confined system. Effects of the pore dimensionality, size, and attractive potential on the correlations between thermodynamic properties of the confined and bulk systems are clarified. A fluid-wall interfacial tension defined as an excess grand potential is evaluated as a function of the pore size. It is found that the tension decreases linearly with the inverse of the pore diameter or width. en-copyright= kn-copyright= en-aut-name=HamadaYoshinobu en-aut-sei=Hamada en-aut-mei=Yoshinobu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KogaKenichiro en-aut-sei=Koga en-aut-mei=Kenichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TanakaHideki en-aut-sei=Tanaka en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=3 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University en-keyword=MONTE-CARLO-SIMULATION kn-keyword=MONTE-CARLO-SIMULATION en-keyword=CARBON NANOTUBES kn-keyword=CARBON NANOTUBES en-keyword=WATER kn-keyword=WATER en-keyword=TRANSITION kn-keyword=TRANSITION en-keyword=NANOSPACES kn-keyword=NANOSPACES en-keyword=ADSORPTION kn-keyword=ADSORPTION en-keyword=NANOPORES kn-keyword=NANOPORES en-keyword=SURFACE kn-keyword=SURFACE en-keyword=LIQUID kn-keyword=LIQUID en-keyword=WALLS kn-keyword=WALLS END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=4 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=20037 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Scanning tunneling microscopy of Dy@C82 and Dy@C60 adsorbed on Si(111)-(7x7) surfaces en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Dy@C-82 and Dy@C-60 adsorbed on Si(111)-(7x7) surface are investigated by scanning tunneling microscopy (STM) at 295 K. The Dy@C-82 molecules in the first layer are adsorbed on the Si(111)-(7x7) surface without formation of islands and nucleation, and the internal structure of the Dy@C-82 molecule is first observed on the surface at 295 K. The average heights of the Dy@C-82 molecules in the first and second layers are estimated to be 7.2 and 10.8 A, respectively, by STM. These results suggest strong interactions between the Si atoms and the Dy@C-82 molecules in the first layer. The STM image reveals that the Dy@C-60 molecule is nearly spherical, showing that the metal endohedral C-60 possesses a cage-form structure.

en-copyright= kn-copyright= en-aut-name=FujikiSatoshi en-aut-sei=Fujiki en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KubozonoYoshihiro en-aut-sei=Kubozono en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=HosokawaTomoko en-aut-sei=Hosokawa en-aut-mei=Tomoko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=KanbaraTakayoshi en-aut-sei=Kanbara en-aut-mei=Takayoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=FujiwaraAkihiko en-aut-sei=Fujiwara en-aut-mei=Akihiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NonogakiYouichi en-aut-sei=Nonogaki en-aut-mei=Youichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=UrisuTsuneo en-aut-sei=Urisu en-aut-mei=Tsuneo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Graduate University for Advanced Studies affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Tohoku University affil-num=5 en-affil= kn-affil=Japan Advanced Institute of Science and Technology affil-num=6 en-affil= kn-affil=Institute for Molecular Science affil-num=7 en-affil= kn-affil=Graduate University for Advanced Studies en-keyword=endohedral metallofullerenes kn-keyword=endohedral metallofullerenes en-keyword=electronic-properties kn-keyword=electronic-properties en-keyword=c-60 kn-keyword=c-60 END start-ver=1.4 cd-journal=joma no-vol=99 cd-vols= no-issue=17 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=200710 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Antiferromagnetic ordering driven by the molecular orbital order of C-60 in alpha '-tetra-kis-(dimethylamino)-ethylene-C-60 en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We have studied the ground state of a fullerene-based magnet, the alpha'-phase tetra-kis-(dimethylamino)ethylene-C-60 (alpha'-TDAE-C-60), by electron spin resonance and magnetic torque measurements. Below T-N = 7 K, nonparamagnetic field dependent resonances with a finite excitation gap ( 1.7 GHz) are observed along the a axis. Strong enhancement in their intensity as temperature is decreased is inconsistent with excitation from a singlet state, which had been proposed for the alpha'-phase ground state. Below T-N, nonquadratic field dependence of the magnetic torque signal is also observed in contrast to quadratic field dependence in the paramagnetic phase. The angle-dependent torque signals below T-N indicate the existence of an anisotropy of the bulk magnetization. From both experiments, we propose an antiferro-magnetic ground state driven by the cooperative orientational ordering of C-60 in the alpha'-TDAE-C-60.

en-copyright= kn-copyright= en-aut-name=KambeTakashi en-aut-sei=Kambe en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KajiyoshiKoichi en-aut-sei=Kajiyoshi en-aut-mei=Koichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=FujiwaraMotoyasu en-aut-sei=Fujiwara en-aut-mei=Motoyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=OshimaKokichi en-aut-sei=Oshima en-aut-mei=Kokichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=2 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=4 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University en-keyword=TDAE-C-60 kn-keyword=TDAE-C-60 en-keyword=Ferromagnetism kn-keyword=Ferromagnetism en-keyword=(NH3)K3C60 kn-keyword=(NH3)K3C60 en-keyword=ESR kn-keyword=ESR END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=22 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20056 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Superconductivity of the ternary boride Li2Pd3B probed by B-11 NMR en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We report a B-11 NMR measurement on the recently discovered superconductor Li2Pd3B. The nuclear spin lattice relaxation rate 1/T-1 shows a well-defined coherence peak just below T-c(H=1.46 T)=5.7 K, and the spin susceptibility measured by the Knight shift also decreases below T-c. These results indicate that the superconductivity is of conventional nature, with an isotropic gap. Our results also suggest that the p-electrons of boron and the d-electrons of palladium that hybridize with boron p-electrons are primarily responsible for the superconductivity.

en-copyright= kn-copyright= en-aut-name=NishiyamaM en-aut-sei=Nishiyama en-aut-mei=M kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=InadaY en-aut-sei=Inada en-aut-mei=Y kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ZhengGuo-qing en-aut-sei=Zheng en-aut-mei=Guo-qing kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=5 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20062 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Field-induced ferromagnetic order and colossal magnetoresistance in la1.2Sr1.8mn2O7:a La139 nmr study en-subtitle= kn-subtitle= en-abstract= kn-abstract=

In order to gain insights into the origin of colossal magnetoresistance (CMR) in manganese oxides, we performed a La-139 NMR study in the double-layered compound La1.2Sr1.8Mn2O7. We find that above the Curie temperature T-C = 126 K, applying a magnetic field induces a long-range ferromagnetic order that persists up to T = 330 K. The critical field at which the induced magnetic moment is saturated coincides with the field at which the CMR effect reaches a maximum. Our results therefore indicate that the CMR observed above T-C in this compound is due to the field-induced ferromagnetism that produces a metallic state via the double exchange interaction.

en-copyright= kn-copyright= en-aut-name=ShiotaniY en-aut-sei=Shiotani en-aut-mei=Y kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=SarraoJ L en-aut-sei=Sarrao en-aut-mei=J L kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=ZhengGuo-qing en-aut-sei=Zheng en-aut-mei=Guo-qing kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Osaka University affil-num=2 en-affil= kn-affil=Los Alamos National Laboratory affil-num=3 en-affil= kn-affil=Okayama University en-keyword=equal-to 0.50 kn-keyword=equal-to 0.50 en-keyword=giant magnetoresistance kn-keyword=giant magnetoresistance en-keyword=resistivity kn-keyword=resistivity en-keyword=manganites kn-keyword=manganites en-keyword=phase kn-keyword=phase en-keyword=crystal kn-keyword=crystal en-keyword=oxides kn-keyword=oxides END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=7 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20052 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Two-photon spectroscopy of core excitons in barium fluoride using synchrotron radiation and laser light en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We have conducted two-photon spectroscopy of core excitons in BaF2. Synchrotron radiation and laser light were used for 5p core-electron excitation and Auger-free luminescence was detected as the signal. Two-photon excitation enables access to f and p orbitals that cannot be reached by one-photon excitation of electrons in p orbitals. It has been found that the spin-orbit splittings of 4f and 6p states of the Ba ion in BaF2 are 0.7 +/- 0.1 and 1.4 +/- 0.1 eV, respectively.

en-copyright= kn-copyright= en-aut-name=TsujibayashiToru en-aut-sei=Tsujibayashi en-aut-mei=Toru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=ItohMinoru en-aut-sei=Itoh en-aut-mei=Minoru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AzumaJunpei en-aut-sei=Azuma en-aut-mei=Junpei kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=WatanabeMasayuki en-aut-sei=Watanabe en-aut-mei=Masayuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=ArimotoOsamu en-aut-sei=Arimoto en-aut-mei=Osamu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=NakanishiShunsuke en-aut-sei=Nakanishi en-aut-mei=Shunsuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Osaka Dental University affil-num=2 en-affil= kn-affil=Shinshu University affil-num=3 en-affil= kn-affil=Synchrotron Light Application Center affil-num=4 en-affil= kn-affil=Kyoto University affil-num=5 en-affil= kn-affil=Okayama University affil-num=6 en-affil= kn-affil=Kagawa University en-keyword=electronicstructure kn-keyword=electronicstructure en-keyword=spectra kn-keyword=spectra en-keyword=absorption kn-keyword=absorption en-keyword=crystals kn-keyword=crystals en-keyword=baf2 kn-keyword=baf2 en-keyword=sns kn-keyword=sns en-keyword=ges kn-keyword=ges END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=23 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=19972 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Scanning tunneling microscopy/spectroscopy studies of two isomers of Ce@C82 on Si(111)-(7×7）surfaces en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Scanning tunneling microscopy images for two isomers of Ce@C-82 were observed on Si(111)-(7x7) at 295 K. The Ce@C-82 molecules in the first layer were bound to the Si surfaces, and the motions were frozen even at 295 K. The multilayer of the Ce@C-82 isomer I (Ce@C-82-I) produced a close-packed structure in the surface layer by annealing the Si substrate at 473 K. The distance between the nearest-neighboring molecules was 1.15(4) nm whose value was consistent with that, 1.12 nm, estimated from x-ray diffraction of the Ce@C-82-I crystals. This implies that the close-packed structure is dominated by van der Waals forces, as in crystals of Ce@C-82-I. The internal structure of Ce@C-82-I was observed in the first layer due to a freeze of molecular motion caused by strong interactions between the molecule and the Si adatoms in the surface. Scanning tunneling spectroscopy revealed that the energy gaps for Ce@C-82-I and -II in the first layer opened to gap energies, E-g of 0.7 and 1.0 eV, respectively. This fact suggests that these molecules are semiconductors with smaller value of E-g than those for C-60 and C-70.

en-copyright= kn-copyright= en-aut-name=FujikiSatoshi en-aut-sei=Fujiki en-aut-mei=Satoshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KubozonoYoshihiro en-aut-sei=Kubozono en-aut-mei=Yoshihiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=RikiishiYoshie en-aut-sei=Rikiishi en-aut-mei=Yoshie kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=UrisuTsuneo en-aut-sei=Urisu en-aut-mei=Tsuneo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=Graduate University for Advanced Studies affil-num=2 en-affil= kn-affil=Science and Technology Agency affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Graduate University for Advanced Studies en-keyword=electronic-structure kn-keyword=electronic-structure en-keyword=endohedral metallofullerenes kn-keyword=endohedral metallofullerenes en-keyword=microscopy kn-keyword=microscopy en-keyword=lanthanum kn-keyword=lanthanum en-keyword=crystal kn-keyword=crystal en-keyword=anion kn-keyword=anion en-keyword=films kn-keyword=films END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue=15 article-no= start-page=7304 end-page=7312 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20041015 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Hydrophobic effect in the pressure-temperature plane en-subtitle= kn-subtitle= en-abstract= kn-abstract=The free energy of the hydrophobic hydration and the strength of the solvent-mediated attraction between hydrophobic solute molecules are calculated in the pressure-temperature plane. This is done in the framework of an exactly soluble model that is an extension of the lattice model proposed by Kolomeisky and Widom [A. B. Kolomeisky and B. Widom, Faraday Discuss. 112, 81 (1999)]. The model takes into account both the mechanism of the hydrophobic effect dominant at low temperatures and the opposite mechanism of solvation appearing at high temperatures and has the pressure as a second thermodynamic variable. With this model, two boundaries are identified in the pressure-temperature plane: the first one within which the solubility, or the Ostwald absorption coefficient, decreases with increasing temperature at fixed pressure and the second one within which the strength of solvent-mediated attraction increases with increasing temperature. The two are nearly linear and parallel to each other, and the second boundary lies in the low-temperature and low-pressure side of the first boundary. It is found that a single, near-linear relation between the hydration free energy and the strength of the hydrophobic attraction holds over the entire area within the second boundary in the pressure-temperature plane. (C) 2004 American Institute of Physics. en-copyright= kn-copyright= en-aut-name=KogaKenichiro en-aut-sei=Koga en-aut-mei=Kenichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University en-keyword=FREE-ENERGY kn-keyword=FREE-ENERGY en-keyword=AQUEOUS ARGON kn-keyword=AQUEOUS ARGON en-keyword=DEPENDENCE kn-keyword=DEPENDENCE en-keyword=WATER kn-keyword=WATER en-keyword=HYDRATION kn-keyword=HYDRATION en-keyword=ENTROPY kn-keyword=ENTROPY en-keyword=MODEL kn-keyword=MODEL en-keyword=DENATURATION kn-keyword=DENATURATION en-keyword=SIMULATIONS kn-keyword=SIMULATIONS en-keyword=ATTRACTION kn-keyword=ATTRACTION END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=14 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20064 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Tomonaga-luttinger liquid in a quasi-one-dimensional s=1 antiferromagnet observed by specific heat measurements en-subtitle= kn-subtitle= en-abstract= kn-abstract=

Specific-heat experiments on single crystals of the S=1 quasi-one-dimensional bond-alternating antiferromagnet Ni(C9H24N4)(NO2)ClO4 (NTENP) have been performed in magnetic fields applied both parallel and perpendicular to the spin chains. We have found for the parallel field configuration that the magnetic specific heat (C-mag) is proportional to temperature (T) above a critical field H-c, at which the energy gap vanishes, in a temperature region above that of the long-range ordered state. The ratio C-mag/T increases as the magnetic field approaches H-c from above. The data are in good quantitative agreement with the prediction of the c=1 conformal field theory in conjunction with the velocity of the excitations calculated by a numerical diagonalization, providing conclusive evidence for a Tomonaga-Luttinger liquid.

en-copyright= kn-copyright= en-aut-name=HagiwaraM en-aut-sei=Hagiwara en-aut-mei=M kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TsujiiH en-aut-sei=Tsujii en-aut-mei=H kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=RotunduC R en-aut-sei=Rotundu en-aut-mei=C R kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=AndrakaB en-aut-sei=Andraka en-aut-mei=B kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=TakanoY en-aut-sei=Takano en-aut-mei=Y kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=TateiwaN en-aut-sei=Tateiwa en-aut-mei=N kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=KobayashiT C en-aut-sei=Kobayashi en-aut-mei=T C kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= en-aut-name=SuzukiT en-aut-sei=Suzuki en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=8 ORCID= en-aut-name=SugaS en-aut-sei=Suga en-aut-mei=S kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=Osaka University affil-num=2 en-affil= kn-affil=The Institute of Physical and Chemical Research affil-num=3 en-affil= kn-affil=University of Florida affil-num=4 en-affil= kn-affil=University of Florida affil-num=5 en-affil= kn-affil=University of Florida affil-num=6 en-affil= kn-affil=Japan Atomic Energy Agency affil-num=7 en-affil= kn-affil=Okayama University affil-num=8 en-affil= kn-affil=Osaka University affil-num=9 en-affil= kn-affil=Osaka University en-keyword=magnetic-field kn-keyword=magnetic-field en-keyword=alternating chain kn-keyword=alternating chain en-keyword=heisenberg chain kn-keyword=heisenberg chain en-keyword=phasetransition kn-keyword=phasetransition en-keyword=cu-2 (c5h12n2)(2)cl-4 kn-keyword=cu-2 (c5h12n2)(2)cl-4 en-keyword=ladders kn-keyword=ladders en-keyword=condensation kn-keyword=condensation en-keyword=charge kn-keyword=charge en-keyword=f5pnn kn-keyword=f5pnn END start-ver=1.4 cd-journal=joma no-vol=97 cd-vols= no-issue=12 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20069 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Generic phase diagram of fermion superfluids with population imbalance en-subtitle= kn-subtitle= en-abstract= kn-abstract=

It is shown by microscopic calculations for trapped imbalanced Fermi superfluids that the gap function always has sign changes, i.e., the Fulde-Ferrell-Larkin-Ovchinnikov (FFLO)-like state, up to a critical imbalance P-c, beyond which normal state becomes stable, at temperature T=0. A temperature-versus-pressure phase diagram is constructed, where the BCS state without sign change is stable only at T not equal 0. We reproduce the observed bimodality in the density profile to identify its origin and evaluate P-c as functions of T and the coupling strength. These dependencies match with the recent experiments.

en-copyright= kn-copyright= en-aut-name=MachidaK en-aut-sei=Machida en-aut-mei=K kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MizushimaT en-aut-sei=Mizushima en-aut-mei=T kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=IchiokaM en-aut-sei=Ichioka en-aut-mei=M kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University en-keyword=molecular-field kn-keyword=molecular-field en-keyword=superconductivity kn-keyword=superconductivity en-keyword=gas kn-keyword=gas END start-ver=1.4 cd-journal=joma no-vol=127 cd-vols= no-issue=4 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070728 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=On the thermodynamic stability of hydrogen clathrate hydrates en-subtitle= kn-subtitle= en-abstract= kn-abstract=The cage occupancy of hydrogen clathrate hydrate has been examined by grand canonical Monte Carlo (GCMC) simulations for wide ranges of temperature and pressure. The simulations are carried out with a fixed number of water molecules and a fixed chemical potential of the guest species so that hydrogen molecules can be created or annihilated in the clathrate. Two types of the GCMC simulations are performed; in one the volume of the clathrate is fixed and in the other it is allowed to adjust itself under a preset pressure so as to take account of compression by a hydrostatic pressure and expansion due to multiple cage occupancy. It is found that the smaller cage in structure II is practically incapable of accommodating more than a single guest molecule even at pressures as high as 500 MPa, which agrees with the recent experimental investigations. The larger cage is found to encapsulate at most 4 hydrogen molecules, but its occupancy is dependent significantly on the pressure of hydrogen. en-copyright= kn-copyright= en-aut-name=KatsumasaKeisuke en-aut-sei=Katsumasa en-aut-mei=Keisuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KogaKenichiro en-aut-sei=Koga en-aut-mei=Kenichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=TanakaHideki en-aut-sei=Tanaka en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=3 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University en-keyword=OCCUPANCY kn-keyword=OCCUPANCY en-keyword=CLUSTERS kn-keyword=CLUSTERS en-keyword=STORAGE kn-keyword=STORAGE en-keyword=CAGES kn-keyword=CAGES en-keyword=WATER kn-keyword=WATER END start-ver=1.4 cd-journal=joma no-vol=122 cd-vols= no-issue=7 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050215 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=On the thermodynamic stability and structural transition of clathrate hydrates en-subtitle= kn-subtitle= en-abstract= kn-abstract=Gas mixtures of methane and ethane form structure II clathrate hydrates despite the fact that each of pure methane and pure ethane gases forms the structure I hydrate. Optimization of the interaction potential parameters for methane and ethane is attempted so as to reproduce the dissociation pressures of each simple hydrate containing either methane or ethane alone. An account for the structural transitions between type I and type II hydrates upon changing the mole fraction of the gas mixture is given on the basis of the van der Waals and Platteeuw theory with these optimized potentials. Cage occupancies of the two kinds of hydrates are also calculated as functions of the mole fraction at the dissociation pressure and at a fixed pressure well above the dissociation pressure. en-copyright= kn-copyright= en-aut-name=KoyamaYuji en-aut-sei=Koyama en-aut-mei=Yuji kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TanakaHideki en-aut-sei=Tanaka en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KogaKenichiro en-aut-sei=Koga en-aut-mei=Kenichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=3 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University en-keyword=STRUCTURE-II kn-keyword=STRUCTURE-II en-keyword=POTENTIAL FUNCTIONS kn-keyword=POTENTIAL FUNCTIONS en-keyword=ETHANE kn-keyword=ETHANE en-keyword=METHANE kn-keyword=METHANE en-keyword=GAS kn-keyword=GAS en-keyword=MOLECULES kn-keyword=MOLECULES en-keyword=MIXTURES kn-keyword=MIXTURES en-keyword=PROPANE kn-keyword=PROPANE en-keyword=WATER kn-keyword=WATER END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=10 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20063 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Observation of a half step magnetization in the {Cu-3}-type triangular spin ring en-subtitle= kn-subtitle= en-abstract= kn-abstract=

We report pulsed field magnetization and ESR experiments on a {Cu-3} nanomagnet, where antiferromagnetically coupled Cu2+ (S=1/2) ions form a slightly distorted triangle. The remarkable feature is the observation of a half step magnetization, hysteresis loops, and an asymmetric magnetization between a positive and a negative field in a fast sweeping external field. This is attributed to an adiabatic change of magnetization. The energy levels determined by ESR unveil that the different mixing nature of a spin chirality of a total S=1/2 Kramers doublet by virtue of Dzyaloshinskii-Moriya interactions is decisive for inducing half step magnetization.

en-copyright= kn-copyright= en-aut-name=ChoiKwang-Yong en-aut-sei=Choi en-aut-mei=Kwang-Yong kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MatsudaYasuhiro H en-aut-sei=Matsuda en-aut-mei=Yasuhiro H kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=NojiriHiroyuki en-aut-sei=Nojiri en-aut-mei=Hiroyuki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Tohoku University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Tohoku University en-keyword=molecular magnets kn-keyword=molecular magnets en-keyword=quantum dynamics kn-keyword=quantum dynamics END start-ver=1.4 cd-journal=joma no-vol=68 cd-vols= no-issue=14 article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=200310 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Polymer phase of the tetrakis(dimethylamino)ethylene-C-60 organic ferromagnet en-subtitle= kn-subtitle= en-abstract= kn-abstract=

High-pressure electron spin resonance (ESR) measurements were performed on tetrakis(dimethylamino) ethylene (TDAE)-C-60 single crystals and stability of the polymeric phase was established in the P-T parameter space. At 7 kbar the system undergoes a ferromagnetic to paramagnetic phase transition due to the pressure-induced polymerization. The polymeric phase remains stable after the pressure release. The depolymerization of the pressure-induced phase was observed at a temperature of 520 K, revealing an unexpectedly high thermal stability of the polymer. Below room temperature, the polymeric phase behaves as a simple Curie-type insulator with one unpaired electron spin per chemical formula. The TDAE(+) donor-related unpaired electron spins, formerly ESR silent, become active above a temperature of 320 K, which demonstrates that the magnetic properties are profoundly defined by miniscule reorientation of TDAE molecules.

en-copyright= kn-copyright= en-aut-name=GarajSlaven en-aut-sei=Garaj en-aut-mei=Slaven kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=KambeTakashi en-aut-sei=Kambe en-aut-mei=Takashi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=Forr?L?szl? en-aut-sei=Forr? en-aut-mei=L?szl? kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=SienkiewiczAndrzej en-aut-sei=Sienkiewicz en-aut-mei=Andrzej kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=FujiwaraMotoyasu en-aut-sei=Fujiwara en-aut-mei=Motoyasu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=OshimaKokichi en-aut-sei=Oshima en-aut-mei=Kokichi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=Institute of Physics of Complex Matter, ?cole Polytechnique F?d?rale de Lausanne affil-num=2 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=3 en-affil= kn-affil=Institute of Physics of Complex Matter, ?cole Polytechnique F?d?rale de Lausanne affil-num=4 en-affil= kn-affil=Institute of Physics, Polish Academy of Sciences affil-num=5 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University affil-num=6 en-affil= kn-affil=Graduate School of Natural Science and Technology, Okayama University END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue=11 article-no= start-page=5488 end-page=5493 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040915 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=On the thermodynamic stability of clathrate hydrates IV: Double occupancy of cages en-subtitle= kn-subtitle= en-abstract= kn-abstract=We have extended the van der Waals and Platteeuw theory to treat multiple occupancy of a single cage of clathrate hydrates, which has not been taken into account in the original theory but has been experimentally confirmed as a real entity. We propose a simple way to calculate the free energy of multiple cage occupancy and apply it to argon clathrate structure II in which a larger cage can be occupied by two argon atoms. The chemical potential of argon is calculated treating it as an imperfect gas, which is crucial to predict accurate pressure dependence of double occupancy expected at high pressure. It is found that double occupancy dominates over single occupancy when the guest pressure in equilibrium with the clathrate hydrate exceeds 270 MPa. (C) 2004 American Institute of Physics. en-copyright= kn-copyright= en-aut-name=TanakaHideki en-aut-sei=Tanaka en-aut-mei=Hideki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=NakatsukaTakeharu en-aut-sei=Nakatsuka en-aut-mei=Takeharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=KogaKenichiro en-aut-sei=Koga en-aut-mei=Kenichiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=2 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University affil-num=3 en-affil= kn-affil=Department of Chemistry, Faculty of Science, Okayama University en-keyword=RAMAN-SCATTERING kn-keyword=RAMAN-SCATTERING en-keyword=HIGH-PRESSURES kn-keyword=HIGH-PRESSURES en-keyword=LIQUID WATER kn-keyword=LIQUID WATER en-keyword=AR HYDRATE kn-keyword=AR HYDRATE en-keyword=MOLECULES kn-keyword=MOLECULES END