result 486 件
| JaLCDOI | 10.18926/AMO/55662 |
|---|---|
| FullText URL | 72_1_47.pdf |
| Author | Ako, Soichiro| Nakamura, Shinichiro| Nouso, Kazuhiro| Dohi, Chihiro| Wada, Nozomu| Morimoto, Yuki| Takeuchi, Yasuto| Yasunaka, Tetsuya| Kuwaki, Kenji| Onishi, Hideki| Ikeda, Fusao| Shiraha, Hidenori| Takaki, Akinobu| Okada, Hiroyuki| |
| Abstract | Transcatheter arterial chemoembolization (TACE) is often performed before radiofrequency ablation (RFA) for the treatment of early-stage hepatocellular carcinoma (HCC). TACE prior to RFA can expand the ablated area and reduce the tumor size, facilitating complete ablation. However, the factors correlated with size reduction remain uncertain. The aim of this study was to identify the factors associated with size reduction by TACE and develop a formula to predict the reduction rate. A total of 100 HCC patients treated with TACE followed by RFA at least 20 days later were enrolled. The tumor size was measured at the time of TACE and RFA, and correlations between the reduction rate and 13 clinical factors were examined. A formula to predict the reduction rate was built using the factors obtained by the analysis. Reduction in the tumor size was observed in 69 nodules, and the median reduction rate was 16.2%. A multivariate regression analysis revealed that a large tumor size (p< 0.01) and a long interval between the therapies (p= 0.01) were factors for a high tumor reduction rate, with tumor size more strongly related to the degree of reduction. A size reduction of more than 10% can be expected by waiting 20 days after TACE when the size of the tumor at TACE is over 25 mm in diameter. The tumor size |
| Keywords | hepatocellular carcinoma transcatheter arterial chemoembolization radiofrequency ablation interval size reduction |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-02 |
| Volume | volume72 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 47 |
| End Page | 52 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29463938 |
| Title Alternative | The 2016 Incentive Award of the Okayama Medical Association in Neuroscience (2016 Niimi Prize) |
|---|---|
| FullText URL | 129_167.pdf |
| Author | Ikeda, Chikako| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2017-12-01 |
| Volume | volume129 |
| Issue | issue3 |
| Start Page | 167 |
| End Page | 169 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.129.167 references https://doi.org/10.1111/bpa.12319 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2017 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.129.167 |
| NAID | 40021393828 |
| JaLCDOI | 10.18926/AMO/55586 |
|---|---|
| FullText URL | 71_6_493.pdf |
| Author | Aoe, Michinori| Ueno-Iio, Tomoe| Shibakura, Misako| Shinohata, Ryoko| Usui, Shinichi| Arao, Yujiro| Ikeda, Satoru| Miyahara, Nobuaki| Tanimoto, Mitsune| Kataoka, Mikio| |
| Abstract | Lavender essential oil (Lvn) has anti-inflammatory effects in an ovalbumin-sensitized murine model of asthma, and inhibits inflammatory cell infiltration into the lungs. The anti-inflammatory effects of Lvn on cell adhesion molecules are not clear. Here we evaluated the effects of Lvn and its main constituents, linalyl acetate (LA) and linalool (LO), on the expression of tumor necrosis factor-alpha (TNF-α)-induced cell adhesion molecules in murine brain endothelial bEnd.3 cells and human umbilical vein endothelial cells (HUVECs). The bEnd.3 cells were treated with Lvn, LA, or LO and subsequently stimulated with TNF-α. The mRNA expression levels of cell adhesion molecules were detected using RT-PCR. E-selectin and P-selectin protein and phosphorylated-NF-κB p65 were detected by western blotting. The effects of Lvn on HUVECs were measured by RT-PCR. In bEnd.3 cells, Lvn and LA suppressed TNF-α-induced E-selectin, P-selectin, vascular cell adhesion molecule-1, intercellular adhesion molecule-1, and phosphorylated-NF-κB p65 in the nucleus; LO did not suppress P-selectin or phosphorylated-NF-κB p65. Lvn inhibited TNF-α-induced E-selectin mRNA in HUVECs. These results indicate that Lvn and LA inhibit TNF-α-induced cell adhesion molecules in endothelial cells through the suppression of NF-κB activation. Consequently, Lvn or other essential oils including LA may be useful as alternative anti-inflammatory medicines. |
| Keywords | lavender essential oil linalyl acetate inflammation cell adhesion molecule NF-κB |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2017-12 |
| Volume | volume71 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 493 |
| End Page | 503 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2017 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29276222 |
| FullText URL | K0005635_abstract_review.pdf K0005635_summary.pdf K0005635_fulltext.pdf |
|---|---|
| Author | Ikeda, Toru| |
| Published Date | 2017-09-29 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5635号 |
| Granted Date | 2017-09-29 |
| Thesis Type | Doctor of Philosophy in Health Sciences |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | ijo_50_1_66.pdf |
|---|---|
| Author | Lee, Suni| Matsuzaki, Hidenori| Maeda, Megumi| Yamamoto, Shoko| Kumagai-Takei, Naoko| Hatayama, Tamayo| Ikeda, Miho| Yoshitome, Kei| Nishimura, Yasumitsu| Otsuki, Takemi| |
| Note | This is an article published by Spandidos Publications| |
| Published Date | 2016-11-22 |
| Publication Title | International Journal of Oncology |
| Volume | volume50 |
| Issue | issue1 |
| Publisher | Spandidos |
| Start Page | 66 |
| End Page | 74 |
| ISSN | 1019-6439 |
| NCID | AA10992511 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | publisher |
| PubMed ID | 27878235 |
| DOI | 10.3892/ijo.2016.3776 |
| Web of Science KeyUT | 000391419200007 |
| Related Url | https://doi.org/10.3892/ijo.2016.3776 |
| FullText URL | ijo_50_6_2024.pdf |
|---|---|
| Author | Maeda, Megumi| Chen, Ying| Lee, Suni| Kumagai-Takei, Naoko| Yoshitome, Kei| Matsuzaki, Hidenori| Yamamoto, Shoko| Hatayama, Tamayo| Ikeda, Miho| Nishimura, Yasumitsu| Otsuki, Takemi| |
| Note | This is an article published by Spandidos Publications| This fulltext availavle in Nov 2017| |
| Published Date | 2017-05-09 |
| Publication Title | International Journal of Oncology |
| Volume | volume50 |
| Issue | issue6 |
| Publisher | Spandidos |
| Start Page | 2024 |
| End Page | 2032 |
| ISSN | 1019-6439 |
| NCID | AA10992511 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | publisher |
| PubMed ID | 28498408 |
| DOI | 10.3892/ijo.2017.3991 |
| Web of Science KeyUT | 000402692100010 |
| Related Url | https://doi.org/10.3892/ijo.2017.3991 |
| FullText URL | Int_J_Hematol_105_6_812.pdf |
|---|---|
| Author | Nishimori, Hisakazu| Fujii, Nobuharu| Fujii, Keiko| Ikeda, Tohru| Asano, Naomi| Ogo, Hiroaki| Yamakawa, Miwa| Takagi, Naoe| Otsuka, Fumio| Ikeda, Kazuma| |
| Keywords | Autologous blood donation Vasovagal reactions |
| Note | This is an Accepted Manuscript of an article published by Springer| |
| Published Date | 2017-06 |
| Publication Title | International Journal of Hematology |
| Volume | volume105 |
| Issue | issue6 |
| Publisher | Elsevier Science |
| Start Page | 812 |
| End Page | 818 |
| ISSN | 0925-5710 |
| NCID | AA10797094 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | author |
| PubMed ID | 28271415 |
| DOI | 10.1007/s12185-017-2204-6 |
| Web of Science KeyUT | 000401324100014 |
| Related Url | isVersionOf https://doi.org/10.1007/s12185-017-2204-6 |
| FullText URL | K0005289_other1.pdf |
|---|---|
| Author | Takeda, Midori| Ikeda, Masanori| Ariumi, Yasuo| Wakita, Takaji| Kato, Nobuyuki| |
| Note | 学位審査副論文| |
| Published Date | 2012-07 |
| Publication Title | Journal of General Virology |
| Volume | volume93 |
| Issue | issue7 |
| Publisher | Cambridge Univ. Press for the Society for General Microbiology |
| Start Page | 1422 |
| End Page | 1431 |
| ISSN | 0022-1317 |
| NCID | AA00698722 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | author |
| PubMed ID | 22456614 |
| DOI | 10.1099/vir.0.040725-0 |
| Web of Science KeyUT | 000306348900003 |
| Related Url | https://doi.org/10.1099/vir.0.040725-0 http://ousar.lib.okayama-u.ac.jp/54272 |
| FullText URL | K0005288_other.pdf |
|---|---|
| Author | Sejima, Hiroe| Mori, Kyoko| Ariumi, Yasuo| Ikeda, Masanori| Kato, Nobuyuki| |
| Keywords | HCV HCV RNA replication system Li23 cells Long-term RNA replication Upregulated host genes Downregulated host genes |
| Note | 学位審査副論文| |
| Published Date | 2012-07 |
| Publication Title | Virus Research |
| Volume | volume167 |
| Issue | issue1 |
| Publisher | Elsevier Science |
| Start Page | 74 |
| End Page | 85 |
| ISSN | 0168-1702 |
| NCID | AA10642076 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | author |
| PubMed ID | 22579597 |
| DOI | 10.1016/j.virusres.2012.04.008 |
| Web of Science KeyUT | 000305496700010 |
| Related Url | https://doi.org/10.1016/j.virusres.2012.04.008 http://ousar.lib.okayama-u.ac.jp/54271 |
| Title Alternative | Achalasia treated with per-oral endoscopic myotomy (POEM) |
|---|---|
| FullText URL | 129_115.pdf |
| Author | Sugihara, Yuusaku| Harada, Keita| Kato, Ryo| Yamauchi, Kenji| Takashima, Shiho| Takei, Daisuke| Inokuchia, Toshihiro| Takahara, Masahiro| Kawano, Seiji| Hiraoka, Sakiko| Tanabe, Shunsuke| Noma, Kazuhiro| Shirakawa, Yasuhiro| Manabe, Noriaki| Inoue, Haruhiro| Okada, Hiroyuki| |
| Abstract | Esophageal achalasia is a disorder of the lower esophageal sphincter muscle. Patients present with dysphagia, chest pain, vomiting, and aspiration. Esophageal achalasia had traditionally been treated with esophageal achalasia balloon dilatation and the Heller-Dor method, but in recent years, the use of per-oral endoscopic myotomy (POEM) has increased. Our patient, a 39-yr-old male, began experiencing dysphagia 4 years prior to his referral to our hospital. Based on the results of esophagogastroduodenoscopy, esophageal radiography and high-resolution manometry, we made the diagnosis of esophageal achalasia (Chicago classification type I) . After informed consent from the patient and his family and approval from our hospital's ethics committee were obtained, we performed a POEM. The patient was discharged on the 4th day post-surgery. At the 1-year post-operative examination, no worsening of symptoms and no relapse were observed. POEM is an excellent treatment method for esophageal achalasia from the perspective of therapeutic effect and prevention of invasion. We recommend that it be considered as the first-choice treatment for achalasia. However, accessibility to the procedure itself is limited due to the few adequately trained operators worldwide. POEM should thus be performed by an expert operator at a high-volume center. |
| Keywords | POEM 食道アカラシア (esophageal achalasia) |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2017-08-01 |
| Volume | volume129 |
| Issue | issue2 |
| Start Page | 115 |
| End Page | 121 |
| ISSN | 0030-1558 |
| Related Url | https://doi.org/10.4044/joma.129.115 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2017 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.129.115 |
| NAID | 130006039377 |
| Title Alternative | The development of a scale to measure stress recognition during the treatment of diabetes patients |
|---|---|
| FullText URL | 129_93.pdf |
| Author | Sumiyoshi, Kazuko| Kawata, Chieko| Okamoto, Tatsuo| Ohashi, Mutsuko| Mikane, Sakae| Takabayashi, Noriko| Futoyu, Yoshiko| Kim, Woesook| Wada, Jun| Shikata, Kenichi| Nakajima, Kazuo| |
| Abstract | The purpose of this study was to establish a measurement scale for "stress recognition in receiving treatment" in patients with diabetes. A self-completed questionnaire was distributed to 149 type-2 diabetes outpatients in March-May 2015 after authorization from Okayama Prefectural University and the ethics committee of the hospital. The "stress recognition in receiving treatment" scale was designed as a second-order factor model consisting of 14 items and the following four factors : the respondent's sense of (1) the burden of being sick, (2) the burden on interpersonal relationships, (3) the burden of treatment, and (4) the burden of medical expenses. Stress recognition in treatment means recognition of being stressed in the burdens related to the illness, interpersonal relationships, treatment and medical expenses. The suitability of the questionnaire data was then evaluated with a structural equation model. The suitability of the factor model to the data satisfied the statistically acceptable standards as Comparative Fit Index (CFI) ＝0.931, Root Mean Square Error of Approximation (RMSEA) ＝0.096, Tucker-Lewis Index (TLI) ＝0.946. As the construct validity was not examined by the scale created in this study or by existing scale, it was verified by using the degrees of mental healthiness and HbA1c that were proved to be associated with the sense of burden. In addition, the construct validity of the questionnaire was supported by a significant correlation between the Japanese version of the WHO-Five Well-being Index (S-WHO-5-J) and the patients' HbA1c levels. The use of this measure is expected to contribute to the early detection of a decline in a diabetic patient's activities of daily living and to the early confirmation of patients' support status. |
| Keywords | 糖尿病患者 (diabetes patients) 治療 (treatment) ストレス認知 (stress recognition) 尺度開発 (development of a scale) |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2017-08-01 |
| Volume | volume129 |
| Issue | issue2 |
| Start Page | 93 |
| End Page | 99 |
| ISSN | 0030-1558 |
| Related Url | https://doi.org/10.4044/joma.129.93 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2017 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.129.93 |
| NAID | 130006039367 |
| FullText URL | K0005478_other1.pdf |
|---|---|
| Author | Matsuzono, Kosuke| Ikeda, Yoshio| Liu, Wentao| Kurata, Tomoko| Deguchi, Shoko| Deguchi, Kentaro| Abe, Koji| |
| Keywords | Prion disease Novelgene mutation 2bp deletion in codon 178 stopcodon at codon 195 Sensoryneuropathy HSAN Pan-autonomicfailure Familial case |
| Note | 岡山大学審査学位副論文| |
| Published Date | 2013-05 |
| Publication Title | European journal of neurology |
| Volume | volume20 |
| Issue | issue5 |
| Publisher | Wiley |
| Start Page | e67 |
| End Page | e69 |
| ISSN | 1351-5101 |
| NCID | AA11015934 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-sa/4.0/deed.ja |
| File Version | author |
| PubMed ID | 23577609 |
| Web of Science KeyUT | 000317609800003 |
| Related Url | https://doi.org/10.1111/ene.12089 http://ousar.lib.okayama-u.ac.jp/55031 |
| Title Alternative | Structure and function of tegmentum vasculosum in avian cochlea |
|---|---|
| FullText URL | poalas_033_026_030.pdf |
| Author | Ikeda, Risa| Otono, Tsuyoshi| Ikeda, Naoya| Saito, Noboru| Ando, Motonori| |
| Abstract | In spite of the importance of endocochlear DC potential (EP) and the K+-rich endolymph for the avian cochlea, the structure and function of the tegmentum vasculosum (TV) has not yet been fully elucidated, compared with those of the stria vascularis in the mammalian cochlea. In this study, we examined structural analysis of the epithelial cells, gene expressions of Na+-K+-ATPase (Atp1A1) and Kir4.1 (Kcnj10), and protein localizations of Na+-K+-ATPase and Kir4.1, in the TV. Tight junctional structures were observed between epithelial dark cells and light cells in the TV. Both Atp1a1 and Kcnj10 genes were detected in the TV. In addition, immunopositive signals for both Na+-K+-ATPase and Kir4.1 were recognized in the TV. These results indicate that Na+-K+-ATPase and Kir4.1 play roles in maintaining the EP and high K+ concentration of the endolymph. Further studies are needed to clarify the physiological functions of the TV. This is the first report which demonstrates that gene and protein expression data contribute to the avian inner ear homeostasis. |
| Publication Title | Proceedings of Okayama Association for Laboratory Animal Science |
| Published Date | 2017-04 |
| Volume | volume33 |
| Start Page | 26 |
| End Page | 30 |
| language | Japanese |
| File Version | publisher |
| Author | Fukugawa, Yoshiyuki| Namimoto, Tomohiro| Toya, Ryo| Saito, Tetsuo| Yuki, Hideaki| Matsuyama, Tomohiko| Ikeda, Osamu| Yamashita, Yasuyuki| Oya, Natsuo| |
|---|---|
| Published Date | 2017-02 |
| Publication Title | Acta Medica Okayama |
| Volume | volume71 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/54822 |
| Author | Horiuchi, Takashi| Yamasaki, Naoko| Ikeda, Keiko| |
|---|---|
| Published Date | 2016-07-25 |
| Publication Title | Journal of the Faculty of Letters Okayama University |
| Volume | volume65 |
| Content Type | Departmental Bulletin Paper |
| JaLCDOI | 10.18926/okadai-bun-kiyou/54784 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Takahashi Nobumasa| Nojima, Ikuko| Araki, Tooru| Takasugi, Mizue| Sakane, Tomoko| Kodera, Aya| Ikeda, Masanori| Tsukahara, Hirokazu| |
| Keywords | Norovirus false positive immunochromatography neonate rapid detection test specificity |
| Published Date | 2015-09-03 |
| Publication Title | Journal of International Medical Research |
| Volume | volume43 |
| Issue | issue5 |
| Publisher | Sage |
| Start Page | 648 |
| End Page | 652 |
| ISSN | 0300-0605 |
| NCID | AA00700686 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 26338763 |
| DOI | 10.1177/0300060515592902 |
| Web of Science KeyUT | 000361592500006 |
| Related Url | isVersionOf https://doi.org/10.1177/0300060515592902 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yoshihara, S.| Fukuda, H.| Tamura, M.| Arisaka, O.| Ikeda, M.| Fukuda, N.| Tsuji, T.| Hasegawa, S.| Kanno, N.| Teraoka, M.| Wakiguchi, H.| Aoki, Y.| Terada, A.| Hasegawa, M.| Manki, A.| Igarashi, H.| |
| Keywords | salmeterol/fluticasone combination asthma infant preschool children nighttime sleep disorder score long-acting beta-agonist inhaled corticosteroid |
| Published Date | 2016-07 |
| Publication Title | Drug Research |
| Volume | volume66 |
| Issue | issue7 |
| Publisher | Georg Thieme |
| Start Page | 371 |
| End Page | 376 |
| ISSN | 2194-9379 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Georg Thieme Verlag |
| File Version | publisher |
| PubMed ID | 27273710 |
| DOI | 10.1055/s-0042-108852 |
| Web of Science KeyUT | 000379389100007 |
| Related Url | isVersionOf https://doi.org/10.1055/s-0042-108852 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Furuya, K.| Nagao, M.| Sato, Y.| Ito, S.| Fujisawa, T.| IPAD3g investigators| |
| Keywords | egg allergy oral food challenge predictive value probability curve specific IgE |
| Note | Masanori Ikeda as IPAD3g investigators| |
| Published Date | 2016-04 |
| Publication Title | Allergy |
| Volume | volume71 |
| Issue | issue10 |
| Publisher | Wiley |
| Start Page | 1435 |
| End Page | 1443 |
| ISSN | 0105-4538 |
| NCID | AA00518456 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 27061295 |
| DOI | 10.1111/all.12912 |
| Web of Science KeyUT | 000386085800007 |
| Related Url | isVersionOf https://doi.org/10.1111/all.12912 |
| FullText URL | K0005400_abstract_review.pdf K0005400_fulltext.pdf |
|---|---|
| Author | Ikeda, Chikako| |
| Published Date | 2016-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5400号 |
| Granted Date | 2016-09-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Title Alternative | The 2015 Incentive Award of the Okayama Medical Association in General Medical Science (2015 Yuuki Prize) |
|---|---|
| FullText URL | 128_91.pdf |
| Author | Kajita, Ai| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2016-08-01 |
| Volume | volume128 |
| Issue | issue2 |
| Start Page | 91 |
| End Page | 94 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.128.91 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2016 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.128.91 |
| NAID | 130005262638 |
