start-ver=1.4 cd-journal=joma no-vol=53 cd-vols= no-issue=3 article-no= start-page=173 end-page=188 dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220520 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=On Kohei Saito’s Two Books kn-title=斎藤幸平著『大洪水の前に』と『人新世の「資本論」』によせて en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=OtaYoshiki en-aut-sei=Ota en-aut-mei=Yoshiki kn-aut-name=太田仁樹 kn-aut-sei=太田 kn-aut-mei=仁樹 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学名誉教授 END start-ver=1.4 cd-journal=joma no-vol=1 cd-vols= no-issue= article-no= start-page=63 end-page=82 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20161230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=De l'histoire litteraire au champ litteraire : Saisei MURO et la poesie japonaise moderne (3) kn-title=文学史から文学場へ : 室生犀星と日本近代詩 (3) en-subtitle= kn-subtitle= en-abstract= kn-abstract=　ある時代のある特定の時期に書かれ発表されたさまざまな文学テクストをながめたばあい、ときにジャンルさえ越えて、そこに流行語のようにいくつかのある特徴的な語や表現が時を同じくして出現してくることがある。それはもちろん作家（詩人）から作家（詩人）へのなんらかの影響関係がそこにあったからだとまずは考えられよう。しかしこれは必ずしもたんに一方から他方への単方向的な影響というのではなく、作家（詩人）たちのあいだで、いくつかの条件があわさって、ほとんど同時発生的にある共通ないし類似の語や表現が生まれたり用いられたりすることもあったのではないか、また、あくまで個々の作品から遡及的にしか見いだされぬとしても、そうした共通ないし類似の語や表現を生みだすことを可能にした、ある時代のある特定の時期に成立していたと想定される表現可能態の言語空間がそこに潜在していたのではないか―― 本稿は、その空間をピエール・ブルデューの用語を借りて「文学場」の名で呼んで、20 世紀初頭における日本の近代詩と19 世紀中葉におけるフランスの近代詩をそうした「文学場」という観点からとらえなおす試みである。 en-copyright= kn-copyright= en-aut-name=UedaKazuhiro en-aut-sei=Ueda en-aut-mei=Kazuhiro kn-aut-name=上田和弘 kn-aut-sei=上田 kn-aut-mei=和弘 aut-affil-num=1 ORCID= affil-num=1 en-affil=Institute for Education and Student Services, Okayama University kn-affil=岡山大学 全学教育・学生支援機構 en-keyword=文学場 kn-keyword=文学場 en-keyword=日本近代詩 kn-keyword=日本近代詩 en-keyword=室生犀星 kn-keyword=室生犀星 en-keyword=北原白秋 kn-keyword=北原白秋 en-keyword=斎藤茂吉 kn-keyword=斎藤茂吉 en-keyword=萩原朔太郎 kn-keyword=萩原朔太郎 END start-ver=1.4 cd-journal=joma no-vol=129 cd-vols= no-issue=2 article-no= start-page=77 end-page=79 dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20170801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The 2016 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2016 Sunada Prize) kn-title=平成28年度岡山医学会賞　胸部・循環研究奨励賞（砂田賞） en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SaitoYukihiro en-aut-sei=Saito en-aut-mei=Yukihiro kn-aut-name=斎藤幸弘 kn-aut-sei=斎藤 kn-aut-mei=幸弘 aut-affil-num=1 ORCID= affil-num=1 en-affil=Department of Cardiovascular Medicine, Okayama University kn-affil=岡山大学病院　循環器内科 END start-ver=1.4 cd-journal=joma no-vol=128 cd-vols= no-issue=3 article-no= start-page=201 end-page=205 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20161201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Ectopic sebaceous glands in the esophagus that became evident over a three-year span kn-title=3 年間の内視鏡所見の変化を観察できた食道異所性皮脂腺の1 例 en-subtitle= kn-subtitle= en-abstract= kn-abstract= A 43-year-old Japanese woman was diagnosed with ectopic sebaceous glands in the esophagus by esophagogastroduodenoscopy and biopsy. At the age of 46, typical ectopic sebaceous glands were recognized in the upper esophagus, whereas yellowish white granules were faintly observed in the lower esophagus. Esophagogastroduodenoscopy examinations were repeated when she was 47 and again at 50 years old, and the lesions in the lower esophagus had become more evident over the ensuing 3 years. Esophageal ectopic sebaceous glands are relatively infrequent, and there have been few case reports describing the progression of the endoscopic features. We also report the clinical and endoscopic features of the five similar cases with pathologically proven ectopic sebaceous glands in the esophagus. en-copyright= kn-copyright= en-aut-name=IwamuroMasaya en-aut-sei=Iwamuro en-aut-mei=Masaya kn-aut-name=岩室雅也 kn-aut-sei=岩室 kn-aut-mei=雅也 aut-affil-num=1 ORCID= en-aut-name=OkadaHiroyuki en-aut-sei=Okada en-aut-mei=Hiroyuki kn-aut-name=岡田裕之 kn-aut-sei=岡田 kn-aut-mei=裕之 aut-affil-num=2 ORCID= en-aut-name=HaradaKeita en-aut-sei=Harada en-aut-mei=Keita kn-aut-name=原田馨太 kn-aut-sei=原田 kn-aut-mei=馨太 aut-affil-num=3 ORCID= en-aut-name=KanzakiHiromitsu en-aut-sei=Kanzaki en-aut-mei=Hiromitsu kn-aut-name=神崎洋光 kn-aut-sei=神崎 kn-aut-mei=洋光 aut-affil-num=4 ORCID= en-aut-name=HoriKeisuke en-aut-sei=Hori en-aut-mei=Keisuke kn-aut-name=堀圭介 kn-aut-sei=堀 kn-aut-mei=圭介 aut-affil-num=5 ORCID= en-aut-name=KitaMasahide en-aut-sei=Kita en-aut-mei=Masahide kn-aut-name=喜多雅英 kn-aut-sei=喜多 kn-aut-mei=雅英 aut-affil-num=6 ORCID= en-aut-name=KawanoSeiji en-aut-sei=Kawano en-aut-mei=Seiji kn-aut-name=川野誠司 kn-aut-sei=川野 kn-aut-mei=誠司 aut-affil-num=7 ORCID= en-aut-name=KawaharaYoshiro en-aut-sei=Kawahara en-aut-mei=Yoshiro kn-aut-name=河原祥朗 kn-aut-sei=河原 kn-aut-mei=祥朗 aut-affil-num=8 ORCID= en-aut-name=TanakaTakehiro en-aut-sei=Tanaka en-aut-mei=Takehiro kn-aut-name=田中健大 kn-aut-sei=田中 kn-aut-mei=健大 aut-affil-num=9 ORCID= en-aut-name=YamamotoKazuhide en-aut-sei=Yamamoto en-aut-mei=Kazuhide kn-aut-name=山本和秀 kn-aut-sei=山本 kn-aut-mei=和秀 aut-affil-num=10 ORCID= affil-num=1 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学 affil-num=2 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学 affil-num=3 en-affil=Department of Endoscopy, Okayama University Hospital kn-affil=岡山大学病院　光学医療診療部 affil-num=4 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学 affil-num=5 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学 affil-num=6 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学 affil-num=7 en-affil=Department of Endoscopy, Okayama University Hospital kn-affil=岡山大学病院　光学医療診療部 affil-num=8 en-affil=Department of Endoscopy, Okayama University Hospital kn-affil=岡山大学病院　光学医療診療部 affil-num=9 en-affil=Department of Pathology, Okayama University Hospital kn-affil=岡山大学病院　病理診断科 affil-num=10 en-affil=Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・肝臓内科学 en-keyword=食道異所性脂腺（ectopic sebaceous glands in the esophagus） kn-keyword=食道異所性脂腺（ectopic sebaceous glands in the esophagus） en-keyword=粘膜下腫瘍（submucosal tumor） kn-keyword=粘膜下腫瘍（submucosal tumor） en-keyword=食道黄色腫（esophageal xanthoma） kn-keyword=食道黄色腫（esophageal xanthoma） END start-ver=1.4 cd-journal=joma no-vol=11 cd-vols= no-issue= article-no= start-page=11 end-page=32 dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20151230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=De l’histoire litt?raire au champ litt?raire: Saisei MURO et la po?sie japonaise moderne (2) kn-title=文学史から文学場へ : 室生犀星と日本近代詩(2) en-subtitle= kn-subtitle= en-abstract= kn-abstract=ある時代のある特定の時期に書かれ発表されたさまざまな文学テクストをながめたばあい、ときにジャンルさえ越えて、そこに流行語のようにいくつかのある特徴的な語や表現が時を同じくして出現してくることがある。それはもちろん作家（詩人）から作家（詩人）へのなんらかの影響関係がそこにあったからだとまずは考えられよう。しかしこれは必ずしもたんに一方から他方への単方向的な影響というのではなく、作家（詩人）たちのあいだで、いくつかの条件があわさって、ほとんど同時発生的にある共通ないし類似の語や表現が生まれたり用いられたりすることもあったのではないか、また、あくまで個々の作品から遡及的にしか見いだされぬとしても、そうした共通ないし類似の語や表現を生みだすことを可能にした、ある時代のある特定の時期に成立していたと想定される表現可能態の言語空間がそこに潜在していたのではないか――本稿は、その空間をピエール・ブルデューの用語を借りて「文学場」の名で呼んで、20 世紀初頭における日本の近代詩と19 世紀中葉におけるフランスの近代詩をそうした「文学場」という観点からとらえなおす試みである。 en-copyright= kn-copyright= en-aut-name=UedaKazuhiro en-aut-sei=Ueda en-aut-mei=Kazuhiro kn-aut-name=上田和弘 kn-aut-sei=上田 kn-aut-mei=和弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学言語教育センター en-keyword=文学場 kn-keyword=文学場 en-keyword=日本近代詩 kn-keyword=日本近代詩 en-keyword=室生犀星 kn-keyword=室生犀星 en-keyword=北原白秋 kn-keyword=北原白秋 en-keyword=斎藤茂吉 kn-keyword=斎藤茂吉 END start-ver=1.4 cd-journal=joma no-vol=161 cd-vols= no-issue= article-no= start-page=(1) end-page=(12) dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Change in quality of the Zen Buddhism with the recognition of Eisai kn-title=栄西呼称の変遷と禅宗の変質 en-subtitle= kn-subtitle= en-abstract= kn-abstract=栄西は一般に臨済宗の開祖とされるが、顕密仏教全体の再興を志した実像とは隔たりがある。そこで栄西認識を示す史料の網羅的な収集を試みた結果、中世顕密仏教につらなる「葉上僧正」という呼称に対抗すべく「千光国師」という呼称が近世に台頭した様相が明らかとなった。国内仏教の一宗派へと転身した近世禅宗の周辺で、栄西の国際的な呼称であった「千光」と、天皇帰依僧への尊称であった「国師」とを組み合わせる動きがあったと想定した。 en-copyright= kn-copyright= en-aut-name=SaitoNatsuki en-aut-sei=Saito en-aut-mei=Natsuki kn-aut-name=斎藤夏来 kn-aut-sei=斎藤 kn-aut-mei=夏来 aut-affil-num=1 ORCID= en-aut-name=TanishikiShogo en-aut-sei=Tanishiki en-aut-mei=Shogo kn-aut-name=谷舗昌吾 kn-aut-sei=谷舗 kn-aut-mei=昌吾 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡＊ 山大学大学院教育学研究科 affil-num=2 en-affil= kn-affil=岡山県立笠岡工業高等学校 en-keyword=葉上僧正 kn-keyword=葉上僧正 en-keyword=千光国師 kn-keyword=千光国師 en-keyword=栄西禅師 kn-keyword=栄西禅師 en-keyword=五山派 kn-keyword=五山派 en-keyword=高峰東ﾗ kn-keyword=高峰東ﾗ en-keyword=近世地誌 kn-keyword=近世地誌 END start-ver=1.4 cd-journal=joma no-vol=128 cd-vols= no-issue=1 article-no= start-page=27 end-page=32 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Beh?et?s disease complicated by ileocecal and esophageal perforation kn-title=回盲部潰瘍穿孔，食道潰瘍穿孔をきたした腸管Beh?et 病の1 手術例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　A 36-year-old Japanese man known to have incomplete Beh?et’s disease (oral aphthous ulcers, genital ulcers, skin lesions, and esophageal and ileocecal ulcers) was admitted to our hospital in January 2011 for abdominal pain. We administered corticosteroids and immunosuppressants. Two months later, we performed an ileocecal resection to control gastrointestinal bleeding from the ileocecal ulcers. High fever persisted after this surgery, and upper gastrointestinal endoscopy demonstrated ulcer penetration between the lower and abdominal esophagus. Eighteen days after the initial ileocecal resection, we performed a lower esophagus resection, gastric tube reconstruction and enterostomy, during which we confirmed a 5-mm-dia. perforated site at the posterior wall of the abdominal esophagus. Postoperative anastomotic leakage and empyema occurred, but they were relieved by thoracic drainage and empyema dissection. en-copyright= kn-copyright= en-aut-name=TsukumoYuta en-aut-sei=Tsukumo en-aut-mei=Yuta kn-aut-name=九十九悠太 kn-aut-sei=九十九 kn-aut-mei=悠太 aut-affil-num=1 ORCID= en-aut-name=KawamotoKazuyuki en-aut-sei=Kawamoto en-aut-mei=Kazuyuki kn-aut-name=河本和幸 kn-aut-sei=河本 kn-aut-mei=和幸 aut-affil-num=2 ORCID= en-aut-name=TakagiKosei en-aut-sei=Takagi en-aut-mei=Kosei kn-aut-name=高木弘誠 kn-aut-sei=高木 kn-aut-mei=弘誠 aut-affil-num=3 ORCID= en-aut-name=ChinKai en-aut-sei=Chin en-aut-mei=Kai kn-aut-name=陳開 kn-aut-sei=陳 kn-aut-mei=開 aut-affil-num=4 ORCID= en-aut-name=MatsubaYuri en-aut-sei=Matsuba en-aut-mei=Yuri kn-aut-name=松葉優里 kn-aut-sei=松葉 kn-aut-mei=優里 aut-affil-num=5 ORCID= en-aut-name=NagahisaYoshio en-aut-sei=Nagahisa en-aut-mei=Yoshio kn-aut-name=長久吉雄 kn-aut-sei=長久 kn-aut-mei=吉雄 aut-affil-num=6 ORCID= en-aut-name=OkabeMichio en-aut-sei=Okabe en-aut-mei=Michio kn-aut-name=岡部道雄 kn-aut-sei=岡部 kn-aut-mei=道雄 aut-affil-num=7 ORCID= en-aut-name=ShirakawaYasuhiro en-aut-sei=Shirakawa en-aut-mei=Yasuhiro kn-aut-name=白川靖博 kn-aut-sei=白川 kn-aut-mei=靖博 aut-affil-num=8 ORCID= en-aut-name=ItohTadashi en-aut-sei=Itoh en-aut-mei=Tadashi kn-aut-name=伊藤雅 kn-aut-sei=伊藤 kn-aut-mei=雅 aut-affil-num=9 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name=藤原俊義 kn-aut-sei=藤原 kn-aut-mei=俊義 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=2 en-affil= kn-affil=倉敷中央病院　消化器外科 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=4 en-affil= kn-affil=倉敷中央病院　消化器外科 affil-num=5 en-affil= kn-affil=倉敷中央病院　消化器外科 affil-num=6 en-affil= kn-affil=倉敷中央病院　消化器外科 affil-num=7 en-affil= kn-affil=倉敷中央病院　消化器外科 affil-num=8 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=9 en-affil= kn-affil=倉敷中央病院　消化器外科 affil-num=10 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 en-keyword=ベーチェット病（Beh?et’s disease） kn-keyword=ベーチェット病（Beh?et’s disease） en-keyword=食道（esophagus） kn-keyword=食道（esophagus） en-keyword=回盲部（ileocecal） kn-keyword=回盲部（ileocecal） en-keyword=穿孔（perforation） kn-keyword=穿孔（perforation） en-keyword=手術（surgery） kn-keyword=手術（surgery） END start-ver=1.4 cd-journal=joma no-vol=128 cd-vols= no-issue=1 article-no= start-page=21 end-page=25 dt-received= dt-revised= dt-accepted= dt-pub-year=2016 dt-pub=20160401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of mucinous adenocarcinoma of the duodenum and literature review of 16 cases reported in Japan kn-title=原発性十二指腸粘液癌の一例― 本邦報告16例の検討― en-subtitle= kn-subtitle= en-abstract= kn-abstract=　Primary mucinous adenocarcinoma of the duodenum is rare. Here we report a case we recently encountered, and we review 16 cases reported in Japan. An 82-year-old Japanese woman was admitted to our hospital complaining of abdominal pain and heartburn. An endoscopic examination revealed a Type 2 tumor in the descending limb of the duodenum, and endoscopically obtained specimens revealed a poorly differentiated adenocarcinoma. We performed a curative pancreatoduodenectomy with lymph node resection, and the surgical specimen revealed that the duodenum was the primary site of the mucinous adenocarcinoma. The patient is currently alive ＞ 1 year after the operation without any evidence of recurrence. Of the 16 patients reviewed, all patients had advanced tumors those depth were T3-T4. 9 patients had lymph node metastasis and 4 patients had peritoneal dissemination at the time of surgery. Since mucinous adenocarcinoma of the duodenum is often progressive cancer at a diagnosis, which is tend to have a worse prognosis than other histological types. en-copyright= kn-copyright= en-aut-name=HamanoIkumi en-aut-sei=Hamano en-aut-mei=Ikumi kn-aut-name=浜野郁美 kn-aut-sei=浜野 kn-aut-mei=郁美 aut-affil-num=1 ORCID= en-aut-name=MatsumotoYusuke en-aut-sei=Matsumoto en-aut-mei=Yusuke kn-aut-name=松本祐介 kn-aut-sei=松本 kn-aut-mei=祐介 aut-affil-num=2 ORCID= en-aut-name=EndoYoshikatsu en-aut-sei=Endo en-aut-mei=Yoshikatsu kn-aut-name=遠藤芳克 kn-aut-sei=遠藤 kn-aut-mei=芳克 aut-affil-num=3 ORCID= en-aut-name=WatanabeNaoki en-aut-sei=Watanabe en-aut-mei=Naoki kn-aut-name=渡邊直樹 kn-aut-sei=渡邊 kn-aut-mei=直樹 aut-affil-num=4 ORCID= en-aut-name=KaiKyouhei en-aut-sei=Kai en-aut-mei=Kyouhei kn-aut-name=甲斐恭平 kn-aut-sei=甲斐 kn-aut-mei=恭平 aut-affil-num=5 ORCID= en-aut-name=SatoShizou en-aut-sei=Sato en-aut-mei=Shizou kn-aut-name=佐藤四三 kn-aut-sei=佐藤 kn-aut-mei=四三 aut-affil-num=6 ORCID= en-aut-name=WaniYoji en-aut-sei=Wani en-aut-mei=Yoji kn-aut-name=和仁洋治 kn-aut-sei=和仁 kn-aut-mei=洋治 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=2 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=3 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=4 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=5 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=6 en-affil= kn-affil=姫路赤十字病院　外科 affil-num=7 en-affil= kn-affil=姫路赤十字病院　病理診断科 en-keyword=原発性十二指腸癌（primary duodenal cancer） kn-keyword=原発性十二指腸癌（primary duodenal cancer） en-keyword=粘液癌（mucinous carcinoma） kn-keyword=粘液癌（mucinous carcinoma） en-keyword=膵頭十二指腸切除（pancreatoduodenectomy） kn-keyword=膵頭十二指腸切除（pancreatoduodenectomy） END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2015 dt-pub=20150630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=肺動脈性肺高血圧症患者におけるニカルジピンによる急性肺血管反応試験 kn-title=Acute Vasoreactivity Testing With Nicardipine in Patients With Pulmonary Arterial Hypertension en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SaitoYukihiro en-aut-sei=Saito en-aut-mei=Yukihiro kn-aut-name=斎藤幸弘 kn-aut-sei=斎藤 kn-aut-mei=幸弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院 END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue= article-no= start-page=15 end-page=34 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=201412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=De l’histoire litt?raire au champ litt?raire : Saisei MURO et la po?sie japonaise moderne(1) kn-title=文学史から文学場へ : 室生犀星と日本近代詩(1) en-subtitle= kn-subtitle= en-abstract= kn-abstract=　ある時代のある特定の時期に書かれ発表されたさまざまな文学テクストをながめたばあ い、ときにジャンルさえ越えて、そこに流行語のようにいくつかのある特徴的な語や表現が 時を同じくして出現してくることがある。それはもちろん作家（詩人）から作家（詩人）へ のなんらかの影響関係がそこにあったからだとまずは考えられよう。しかしこれは必ずしも たんに一方から他方への単方向的な影響というのではなく、作家（詩人）たちのあいだで、 いくつかの条件があわさって、ほとんど同時発生的にある共通ないし類似の語や表現が生ま れたり用いられたりすることもあったのではないか、また、あくまで個々の作品から遡及的 にしか見いだされぬとしても、そうした共通ないし類似の語や表現を生みだすことを可能に した、ある時代のある特定の時期に成立していたと想定される表現可能態の言語空間がそこ に潜在していたのではないか――本稿は、その空間をピエール・ブルデューの用語を借りて 「文学場」の名で呼んで、20 世紀初頭における日本の近代詩と19 世紀中葉におけるフラン スの近代詩をそうした「文学場」という観点からとらえなおす試みである。 en-copyright= kn-copyright= en-aut-name=UedaKazuhiro en-aut-sei=Ueda en-aut-mei=Kazuhiro kn-aut-name=上田和弘 kn-aut-sei=上田 kn-aut-mei=和弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学言語教育センター en-keyword=文学場 kn-keyword=文学場 en-keyword=日本近代詩 kn-keyword=日本近代詩 en-keyword=室生犀星 kn-keyword=室生犀星 en-keyword=北原白秋 kn-keyword=北原白秋 en-keyword=斎藤茂吉 kn-keyword=斎藤茂吉 END start-ver=1.4 cd-journal=joma no-vol=157 cd-vols= no-issue= article-no= start-page=(21) end-page=(27) dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20141127 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Consideration of the Ichinomiya system based on Bizen Kibitsunomiya kn-title=備前吉備津宮からみた一宮制 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　備前一宮とされる吉備津宮に関連する「備前国一宮社法」「備前国総社家社僧中神前御祈念之事等注文」「備前一宮御神事絵巻」は、室町時 代の年紀を有し、中世史料と考えられてきた。しかし、人名、地名、および「国主」という用語に即して関連史料を探索してみると、近世初 期に成立した史料と考えられる。それでも史料の作成者が、康永や文明など中世の年号を付したのは、中世松田氏が近世池田氏の前身だとい う近世初期の歴史認識の現れと考察した。 en-copyright= kn-copyright= en-aut-name=SaitoNatsuki en-aut-sei=Saito en-aut-mei=Natsuki kn-aut-name=斎藤夏来 kn-aut-sei=斎藤 kn-aut-mei=夏来 aut-affil-num=1 ORCID= en-aut-name=TabuchiHikaru en-aut-sei=Tabuchi en-aut-mei=Hikaru kn-aut-name=田淵光 kn-aut-sei=田淵 kn-aut-mei=光 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院教育学研究科　社会・言語教育学系 affil-num=2 en-affil= kn-affil=クラブン株式会社 en-keyword=備前吉備津宮 kn-keyword=備前吉備津宮 en-keyword=備前国一宮社法 kn-keyword=備前国一宮社法 en-keyword=備前国総社家社僧中神前御祈念之事等注文 kn-keyword=備前国総社家社僧中神前御祈念之事等注文 en-keyword=備前一宮御神事絵巻 kn-keyword=備前一宮御神事絵巻 en-keyword=国主 kn-keyword=国主 en-keyword=松田氏 kn-keyword=松田氏 END start-ver=1.4 cd-journal=joma no-vol=126 cd-vols= no-issue=2 article-no= start-page=109 end-page=115 dt-received= dt-revised= dt-accepted= dt-pub-year=2014 dt-pub=20140801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Comprehensive treatment for gender identity disorder kn-title=性同一性障害に対する包括的治療 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NambaYuzaburo en-aut-sei=Namba en-aut-mei=Yuzaburo kn-aut-name=難波祐三郎 kn-aut-sei=難波 kn-aut-mei=祐三郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院　ジェンダーセンター en-keyword=性同一性障害 kn-keyword=性同一性障害 en-keyword=包括的治療 kn-keyword=包括的治療 en-keyword=性別適合手術 kn-keyword=性別適合手術 END start-ver=1.4 cd-journal=joma no-vol=154 cd-vols= no-issue= article-no= start-page=(1) end-page=(15) dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20131125 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Historical Material“ Kokuenshoukan - the Historical Records of Iwami Ankokuji Temple -” kn-title=石見安国寺誌・国苑掌鑑 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　島根県浜田市の古刹石見安国寺に伝来したとみられる「国苑掌鑑」は、江戸時代の同寺住持?州源麗が編輯した石見安国寺誌で、安永四年（一七七五）にまとめられている。同書の存在は早くから知られていたが、断片的に参照されるに止まり、収録されている鎌倉時代後期以来の古文書についても、「鎌倉遺文」「南北朝遺文」などの翻刻対象から洩れているものを含む。室町将軍や徳川将軍の任命対象であった石見安国寺の歴代住持に関する情報を得られる点でも貴重であり、今回まとめて全文を翻刻紹介する。 en-copyright= kn-copyright= en-aut-name=SaitoNatsuki en-aut-sei=Saito en-aut-mei=Natsuki kn-aut-name=斎藤夏来 kn-aut-sei=斎藤 kn-aut-mei=夏来 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院教育学研究科社会・言語教育学系社会科教育講座 en-keyword=国苑掌鑑 kn-keyword=国苑掌鑑 en-keyword=?州源麗 kn-keyword=?州源麗 en-keyword=石見安国寺 kn-keyword=石見安国寺 en-keyword=石見益田氏 kn-keyword=石見益田氏 en-keyword=島根県立図書館 kn-keyword=島根県立図書館 en-keyword=花園大学今津文庫 kn-keyword=花園大学今津文庫 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=スマートアクチュエータのヒステリシス特性を考慮したフレキシブルアームのオペレータ理論に基づく振動制御 kn-title=Operator-based vibration control of a flexible arm using smart actuators with hysteresis en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SaitoSeiji en-aut-sei=Saito en-aut-mei=Seiji kn-aut-name=斎藤誠二 kn-aut-sei=斎藤 kn-aut-mei=誠二 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=124 cd-vols= no-issue=1 article-no= start-page=63 end-page=66 dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Pathological complete response of advanced gastric cancer with pyloric stenosis to neoadjuvant S-1/CDDP chemotherapy: A case report kn-title=S-1/CDDP術前化学療法により組織学的CRが得られた幽門狭窄合併進行胃癌の１例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 59-year-old man with epigastric discomfort and anorexia was referred to our hospital. Endoscopy revealed a type 3 advanced gastric cancer with pyloric stenosis diagnosed as a poorly differentiated adenocarcinoma in the biopsy specimens. A gastrojejunal bypass operation was performed because of direct invasion to the pancreas. The patient was treated by three courses of neoadjuvant chemotherapy with S-1/CDDP. Follow-up abdominal CT scan revealed that the primary tumor had become smaller, suggesting that a partial response had been achieved. Distal gastrectomy with D2 lymphadenectomy was performed. The histopathological examination showed no residual cancer cells in the primary lesion or dissected lymph nodes. Final chemotherapy efficacy was evaluated as Grade 3. The patient was treated with S-1 for one year after the gastrectomy and lymphadenectomy and has been followed up for 18 months without evidence of recurrence. en-copyright= kn-copyright= en-aut-name=NishizakiMasahiko en-aut-sei=Nishizaki en-aut-mei=Masahiko kn-aut-name=西崎正彦 kn-aut-sei=西崎 kn-aut-mei=正彦 aut-affil-num=1 ORCID= en-aut-name=FujiwaraYasuhiro en-aut-sei=Fujiwara en-aut-mei=Yasuhiro kn-aut-name=藤原康宏 kn-aut-sei=藤原 kn-aut-mei=康宏 aut-affil-num=2 ORCID= en-aut-name=ChoudaYasuhiro en-aut-sei=Chouda en-aut-mei=Yasuhiro kn-aut-name=丁田泰宏 kn-aut-sei=丁田 kn-aut-mei=泰宏 aut-affil-num=3 ORCID= en-aut-name=KanazawaTakashi en-aut-sei=Kanazawa en-aut-mei=Takashi kn-aut-name=金澤卓 kn-aut-sei=金澤 kn-aut-mei=卓 aut-affil-num=4 ORCID= en-aut-name=NinomiyaMotoki en-aut-sei=Ninomiya en-aut-mei=Motoki kn-aut-name=二宮基樹 kn-aut-sei=二宮 kn-aut-mei=基樹 aut-affil-num=5 ORCID= en-aut-name=FujiwaraToshiyoshi en-aut-sei=Fujiwara en-aut-mei=Toshiyoshi kn-aut-name=藤原俊義 kn-aut-sei=藤原 kn-aut-mei=俊義 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 affil-num=2 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=3 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=4 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=5 en-affil= kn-affil=広島市立広島市民病院　外科 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器外科学 en-keyword=幽門狭窄 (pyloric stenosis) kn-keyword=幽門狭窄 (pyloric stenosis) en-keyword=進行胃癌 (advanced gastric cancer) kn-keyword=進行胃癌 (advanced gastric cancer) en-keyword=S-1/CDDP kn-keyword=S-1/CDDP en-keyword=術前化学療法 (neoadjuvant chemotherapy) kn-keyword=術前化学療法 (neoadjuvant chemotherapy) en-keyword=組織学的CR (pathological CR) kn-keyword=組織学的CR (pathological CR) END start-ver=1.4 cd-journal=joma no-vol=118 cd-vols= no-issue=3 article-no= start-page=187 end-page=192 dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=原発性肺高血圧症の進行メカニズムの解明と治療薬の開発 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=小川愛子 kn-aut-sei=小川 kn-aut-mei=愛子 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=中村一文 kn-aut-sei=中村 kn-aut-mei=一文 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=松原広己 kn-aut-sei=松原 kn-aut-mei=広己 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=藤尾栄起 kn-aut-sei=藤尾 kn-aut-mei=栄起 aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=池田哲也 kn-aut-sei=池田 kn-aut-mei=哲也 aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=宮地克維 kn-aut-sei=宮地 kn-aut-mei=克維 aut-affil-num=6 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=三浦大志 kn-aut-sei=三浦 kn-aut-mei=大志 aut-affil-num=7 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=三浦綾 kn-aut-sei=三浦 kn-aut-mei=綾 aut-affil-num=8 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=永瀬聡 kn-aut-sei=永瀬 kn-aut-mei=聡 aut-affil-num=9 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=草野研吾 kn-aut-sei=草野 kn-aut-mei=研吾 aut-affil-num=10 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=伊達洋至 kn-aut-sei=伊達 kn-aut-mei=洋至 aut-affil-num=11 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=大江透 kn-aut-sei=大江 kn-aut-mei=透 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=University of California, San Diego, Division of Pulmonary and Critical Care Medicine affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科循環器内科 affil-num=3 en-affil= kn-affil=国立病院機構岡山医療センター循環器科 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科循環器内科 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科循環器内科 affil-num=6 en-affil= kn-affil=国立病院機構岡山医療センター循環器科 affil-num=7 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科循環器内科 affil-num=8 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科循環器内科 affil-num=9 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科循環器内科 affil-num=10 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科循環器内科 affil-num=11 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科腫瘍・胸部外科 affil-num=12 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科循環器内科 en-keyword=原発性肺高血圧症 kn-keyword=原発性肺高血圧症 en-keyword=平滑筋細胞 kn-keyword=平滑筋細胞 en-keyword=prednisolone kn-keyword=prednisolone en-keyword=細胞周期 kn-keyword=細胞周期 END start-ver=1.4 cd-journal=joma no-vol=147 cd-vols= no-issue= article-no= start-page=125 end-page=133 dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110625 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on the Development of the Practice in Early Childhood Care and Education to Improve Both the Way to Grasp Its Goals and the Practice Itself Qualitatively kn-title=保育目標のとらえ方と保育実践の両者を質的に向上させる保育実践開発に関する考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=今日の保育園には，保育課程経営の実現が求められている。保育課程経営とは，保育課程開発の各段階とそれに対応する経営活動をPDCAサイクルにのせて推進し，より豊かな園の保育を実現しようとする営みであるといえる。その実現のためのアクション・リサーチが，私立御南保育園において実施されている。同リサーチでは，実効のある保育目標の明確化過程をとおして，保育目標の明確化手順を開発し､その上で，所属保育士有志が，実効のある保育目標を達成するためのより発展的な保育実践を開発しようとする取り組みを行っている。本研究では，その過程の分析をとおして，実効のある保育目標を前提にした保育実践開発が，保育目標のとらえ方と保育実践の両者を質的に向上させる可能性があることとその実現のための課題について考察している。 en-copyright= kn-copyright= en-aut-name=YokomatsuTomoyoshi en-aut-sei=Yokomatsu en-aut-mei=Tomoyoshi kn-aut-name=横松友義 kn-aut-sei=横松 kn-aut-mei=友義 aut-affil-num=1 ORCID= en-aut-name=WatanabeYuzo en-aut-sei=Watanabe en-aut-mei=Yuzo kn-aut-name=渡邊祐三 kn-aut-sei=渡邊 kn-aut-mei=祐三 aut-affil-num=2 ORCID= en-aut-name=MoriHideko en-aut-sei=Mori en-aut-mei=Hideko kn-aut-name=森英子 kn-aut-sei=森 kn-aut-mei=英子 aut-affil-num=3 ORCID= en-aut-name=IseMakoto en-aut-sei=Ise en-aut-mei=Makoto kn-aut-name=伊勢慎 kn-aut-sei=伊勢 kn-aut-mei=慎 aut-affil-num=4 ORCID= en-aut-name=ToyoikeRie en-aut-sei=Toyoike en-aut-mei=Rie kn-aut-name=豊池利江 kn-aut-sei=豊池 kn-aut-mei=利江 aut-affil-num=5 ORCID= en-aut-name=SaitoKenji en-aut-sei=Saito en-aut-mei=Kenji kn-aut-name=斎藤健司 kn-aut-sei=斎藤 kn-aut-mei=健司 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院教育学研究科発達支援学系 affil-num=2 en-affil= kn-affil=御南保育園 affil-num=3 en-affil= kn-affil=白ゆり保育園 affil-num=4 en-affil= kn-affil=福岡女子短期大学 affil-num=5 en-affil= kn-affil=聖華保育園 affil-num=6 en-affil= kn-affil=新見公立短期大学 en-keyword=保育目標のとらえ方 kn-keyword=保育目標のとらえ方 en-keyword=保育実践 kn-keyword=保育実践 en-keyword=質的向上 kn-keyword=質的向上 en-keyword=保育課程開発 kn-keyword=保育課程開発 en-keyword=保育課程経営 kn-keyword=保育課程経営 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=血管新生negative feedback制御因子Vasohibin-1による2型糖尿病マウスにおける腎症進展抑制効果の検討 kn-title=Amelioration of renal alterations in obese type 2 diabetic mice by vasohibin-1, a negative feedback regulator of angiogenesis en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SaitoDaisuke en-aut-sei=Saito en-aut-mei=Daisuke kn-aut-name=斎藤大輔 kn-aut-sei=斎藤 kn-aut-mei=大輔 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=123 cd-vols= no-issue=2 article-no= start-page=141 end-page=144 dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Japanese guideline for management of lateral epicondylitis kn-title=上腕骨外側上顆炎の診療ガイドライン en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ShimamuraYasunori en-aut-sei=Shimamura en-aut-mei=Yasunori kn-aut-name=島村安則 kn-aut-sei=島村 kn-aut-mei=安則 aut-affil-num=1 ORCID= en-aut-name=InoueMadoka en-aut-sei=Inoue en-aut-mei=Madoka kn-aut-name=井上円加 kn-aut-sei=井上 kn-aut-mei=円加 aut-affil-num=2 ORCID= en-aut-name=OzawaMasatugu en-aut-sei=Ozawa en-aut-mei=Masatugu kn-aut-name=小澤正嗣 kn-aut-sei=小澤 kn-aut-mei=正嗣 aut-affil-num=3 ORCID= en-aut-name=KanazawaTomoko en-aut-sei=Kanazawa en-aut-mei=Tomoko kn-aut-name=金澤智子 kn-aut-sei=金澤 kn-aut-mei=智子 aut-affil-num=4 ORCID= en-aut-name=SaitouTaiichi en-aut-sei=Saitou en-aut-mei=Taiichi kn-aut-name=斎藤太一 kn-aut-sei=斎藤 kn-aut-mei=太一 aut-affil-num=5 ORCID= en-aut-name=NakaharaRyuichi en-aut-sei=Nakahara en-aut-mei=Ryuichi kn-aut-name=中原龍一 kn-aut-sei=中原 kn-aut-mei=龍一 aut-affil-num=6 ORCID= en-aut-name=NodaTomoyuki en-aut-sei=Noda en-aut-mei=Tomoyuki kn-aut-name=野田知之 kn-aut-sei=野田 kn-aut-mei=知之 aut-affil-num=7 ORCID= en-aut-name=NishidaKeiichiro en-aut-sei=Nishida en-aut-mei=Keiichiro kn-aut-name=西田圭一郎 kn-aut-sei=西田 kn-aut-mei=圭一郎 aut-affil-num=8 ORCID= en-aut-name=OzakiToshifumi en-aut-sei=Ozaki en-aut-mei=Toshifumi kn-aut-name=尾ｱ敏文 kn-aut-sei=尾ｱ kn-aut-mei=敏文 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院　整形外科 affil-num=2 en-affil= kn-affil=岡山大学病院　整形外科 affil-num=3 en-affil= kn-affil=岡山大学病院　整形外科 affil-num=4 en-affil= kn-affil=岡山大学病院　整形外科 affil-num=5 en-affil= kn-affil=岡山大学病院　整形外科 affil-num=6 en-affil= kn-affil=岡山大学病院　整形外科 affil-num=7 en-affil= kn-affil=岡山大学病院　整形外科 affil-num=8 en-affil= kn-affil=岡山大学病院　整形外科 affil-num=9 en-affil= kn-affil=岡山大学病院　整形外科 END start-ver=1.4 cd-journal=joma no-vol=123 cd-vols= no-issue=1 article-no= start-page=33 end-page=38 dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Investigation of laparoscopic therapy in 56 cases of duodenal ulcer perforation kn-title=十二指腸潰瘍穿孔に対する治療法の適応についての検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Background: Although conservative therapy has been acceptable as the first-line therapy for duodenal ulcer (DU) perforations, surgical therapies are known to have certain advantages. We investigated the indications for laparoscopic (LS) or open surgery (OS) or conservative therapy (CoT) among 56 DU perforation cases over 5 years. Methods: 31 LSs, 22 OSs and 5 CoTs were analyzed for patient's physical and surgical factors and clinical course. Results: Mean age was 51.6. Male/female ratio was 49/9. Survival ratio was 98%. Although the hospital stay (10.9 vs 19.5 days) and analgesic administrations (1.9 vs 4.6 days) were significantly shorter in LS than OS, almost all OS patients were in serious condition as evidenced by longer waiting time before treatment, stronger pain, bigger hole of perforation, more ascites accumulation and higher morbidity of complications. Two cases of multisurgery were experienced in both LS and OS groups due to leakage of seam, abscess formation, relapsed ulcer or idiopathic intestinal perforation. LS is a therapy more widely usable and more beneficial than the other two. Conclusion: LS, a minimally invasive surgery for DU perforation, should be considered as a first-line standard therapy because of significant advantages such as shorter hospital stay. OS or CoT may be selected when appropriate. en-copyright= kn-copyright= en-aut-name=IshidoNobuhiro en-aut-sei=Ishido en-aut-mei=Nobuhiro kn-aut-name=石堂展宏 kn-aut-sei=石堂 kn-aut-mei=展宏 aut-affil-num=1 ORCID= en-aut-name=TamuraRyuji en-aut-sei=Tamura en-aut-mei=Ryuji kn-aut-name=田村竜二 kn-aut-sei=田村 kn-aut-mei=竜二 aut-affil-num=2 ORCID= en-aut-name=OkamotoTakahiro en-aut-sei=Okamoto en-aut-mei=Takahiro kn-aut-name=岡本貴大 kn-aut-sei=岡本 kn-aut-mei=貴大 aut-affil-num=3 ORCID= en-aut-name=KadowakiYoshihiko en-aut-sei=Kadowaki en-aut-mei=Yoshihiko kn-aut-name=門脇嘉彦 kn-aut-sei=門脇 kn-aut-mei=嘉彦 aut-affil-num=4 ORCID= en-aut-name=MoriTakashi en-aut-sei=Mori en-aut-mei=Takashi kn-aut-name=森隆 kn-aut-sei=森 kn-aut-mei=隆 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=神戸赤十字病院　外科 affil-num=2 en-affil= kn-affil=神戸赤十字病院　外科 affil-num=3 en-affil= kn-affil=神戸赤十字病院　外科 affil-num=4 en-affil= kn-affil=神戸赤十字病院　外科 affil-num=5 en-affil= kn-affil=神戸赤十字病院　外科 en-keyword=十二指腸潰瘍穿孔 (duodenal ulcer perforation) kn-keyword=十二指腸潰瘍穿孔 (duodenal ulcer perforation) en-keyword=腹腔鏡手術 (laparoscopic surgery) kn-keyword=腹腔鏡手術 (laparoscopic surgery) en-keyword=保存療法 (conservative therapy) kn-keyword=保存療法 (conservative therapy) END start-ver=1.4 cd-journal=joma no-vol=64 cd-vols= no-issue=3 article-no= start-page=338 end-page=346 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=19520331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=大脳皮質手術的侵襲の自律神経機能に及ぼす影響に関する臨床的研究 第II編 大脳皮質手術的侵襲の温熱性発汗に及ぼす影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=斎藤滋 kn-aut-sei=斎藤 kn-aut-mei=滋 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一（陣内）外科教室 END start-ver=1.4 cd-journal=joma no-vol=64 cd-vols= no-issue=3 article-no= start-page=317 end-page=337 dt-received= dt-revised= dt-accepted= dt-pub-year=1952 dt-pub=19520331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=大腦皮質手術的侵襲の自律神経機能に及ぼす影響に関する臨床的研究 第I編 大脳皮質手術的侵襲の皮膚温度に及ぼす影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=斎藤滋 kn-aut-sei=斎藤 kn-aut-mei=滋 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一（陣内）外科教室 END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=3 article-no= start-page=673 end-page=690 dt-received= dt-revised= dt-accepted= dt-pub-year=1957 dt-pub=19570331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on Heinz's Body Part Three: Observations on Heinz's Body in Experimental, Anemic Domestic Rabbits and the Application of Phase-Contrast Microscope on Heinz's Boby kn-title=ハインツ氏小体に関する研究 第三編 諸種実験的貧血家兎に於けるハインツ氏小体の観察及び位相差顕微鏡のハインツ氏小体への応用 en-subtitle= kn-subtitle= en-abstract= kn-abstract=1. In the case of acute, depleted domestic rabbits, Heinz's body appeared in an intermediate degree 12 hours after the depletion, while in the case of chromic, depleted rabbits a slight or an intermediate acceleration of the Heinz-body formation was noticed 24 hours after the depletion and there on. From this the penetrability through the wall of erythrocytes seems to have an important relationship with the formation of Heinz's body. 2. The formation of Heinz's body is quite high in the case of the rabbits inoculated with phenylhydrazin, thus the penetrability in this case also, raises a question. 3. In the rabbits injected with benzol, the formation of Heinz's body has been of a high degree, and their recovery necessitates an extremely long period of time. 4. In the case of those receiving saponin injection, a mild degree of the formation of Heinz's body started 8 days after the initial injection, but after the cessation of the injection the formation decreased rapidly along with the improvement of hematic picture; and four days after the cessation all returned to normal. 5. In the kollargol injection cases, an intermediate degree of the formation was noticed 8 to 12 days afterwards, and it was found that the reticulo-endothelial system has something to do with the elimination of Heinz's body. 6. With the use of a phase-contrast microscope, Heinz's body in the form of unstained specimens had been possible of observation in each contrast but reticulated erythrocytes could not be observed. This seems to be due to the fact that there is no difference at all in the phase-contrast between the reticulated substances of reticulated erythrocytes and the cytoplasmas of erythrocytes. en-copyright= kn-copyright= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=3 article-no= start-page=649 end-page=672 dt-received= dt-revised= dt-accepted= dt-pub-year=1957 dt-pub=19570331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on Heinz's Body Part two: Observations on Heinz's Body in Various Anemic Patients, in the Domestic Rabbits Injected with the Serum of Anemics, and in the Erythrocytes of Normal Person Treated with the Anemic Serum kn-title=ハインツ氏小体に関する研究 第二編 諸種血液疾患々者,患者血清注射家兎及び患者血清添加健康人赤血球に於けるハインツ氏小体の観察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=1. Of 110 anemic patients observed in the determination of Heinz's body, the patients suffering from aplastic anemia gave the highest value and then those of leukemia, anchylostomiasis, Banti's syndrome, hemorrhagic anemia, essential chlorosis, aglanulocytosis, endocarditis lenta, and Welhoff's disease, in the order mentioned. 2. In the case of the domestic rabbits inoculated with sera of various anemics at the dose of 2cc/kg each, continuously for one week, the order of anemias, if arranged according to the rates of the Heinz-body appearance, will be aplastic anemia, leukemia, anchylostomiasis, Banti's syndrome, essential chlorosis, hemorrhagic anemia, and Welhoff's disease. From this result, practically no substance accelerating the formation of Heinz's body appears to be in the sera of hemorrhagic anemia and Welhoff's disease, while such substances may be thought to exist in the rest of anemic sera (although in the case of essential chlorosis, it is not definitely certain). 3. When the erythrocytes of normal person were left suspended in the sera of various anemics for 3 hours and these erythrocytes measured separately for Heinz's body, the order of diseases arranged according to the rates of the appearance of Heinz's body was more or less like as follows: aplastic anemia, leukemia, anchylostomiasis, Banti's syndrome, essential chlorosis, hemorrhagic anemia, and Welhoff's disease. 4. From these results, it is clear that whether the determination for Heinz's body be made with the blood directly tapped from the patient, or with the domestic rabbits receiving the anemic serum continuously for one week, or with the blood of normal person treated with an anemic serum, in vitro, any one of the three methods proves to be an invaluable aid in differentiation of the anemic patients and in determination of seriousness of the disease itself. Furthermore, it may be assumed that in the sera of the anemics, there exist some subclinic, intrinsic toxins which accelerate the formation of Heinz's body, and that the quantity of such toxins has an important bearing on the estimated values obtained from the blood directly drawn from the patients. Hence in the case of hemorrhagic anemia, the penetrability of Heinz's corpuscles through the wall of erythrocytes should be given an especial consideration. The serum of anemic patient has been found to accelerate the formation of Heinz's body even when made to act directly upon the erythrocytes of the normal persons, in vitro. en-copyright= kn-copyright= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=69 cd-vols= no-issue=3 article-no= start-page=627 end-page=647 dt-received= dt-revised= dt-accepted= dt-pub-year=1957 dt-pub=19570331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on Heinz's Body Part One: Hydrogen-Bomb Cases and Experimental Domestic Rabbits Exposd to Radio-activity, both Observed on the Basis of the Appearance of Heinz's Body kn-title=ハインツ氏小体に関する研究 第一編 ハインツ氏小体出現を中心として観たビキニ水爆症及び実験的放射能障碍家兎に就て en-subtitle= kn-subtitle= en-abstract= kn-abstract=By determining at first the appearance of Heinz's body in man and male domestic rabbits, both normal, with the Yoshida-Kawamura method, and next by investigating the rate of the appearance of Heinz's body in Bikini hydrogen-bomb patients and in the domestic rabbits injected with radio-isotope P(32) as well as in the rabbits exposed to X-ray, the author obtained the following results: 1. Two separate groups of male and female, each consisting of 25 persons, were selected and the rate of the Heinz-body appearance was determined; and as the result, the average rates of the appearance of each were found to be 63.88‰ (male) and 66.52‰ (female) respectively; thus the average value of females was slightly higher. On the other hand, in the 62 normal male rabbits similarly measured, the average value of the appearance of Heinz's body was found to be 22.19‰. 2. In the case of the 7 fishermen passing through the Bikini area and having shown no apparent clinical disorders, the rate of Heinz-body appearance was found to be still high, yet within 3 to 4 weeks after the examination, it returned to normal, paralleling more or less with the change of blood-iron contents, Sideroblastogram, and the results of Bone marrow tissue culture. In view of this, in establishing a criterion of the recovery of these hydrogenbomb cases, it seems that scrupulous daily examinations such as mentioned previously are of urgent necessity. 3. In the domestic rabbits receiving the injection of 100 μc. P(32)/kg, Heinz's body increased 6 hours after the injection but it returned to normal after 20 to 42 days; even then they maintained a high value of blood-iron contents and showed an unmistakable evidence of radio-active substance in the bone as well. Whereas those rabbits receiving the dose of 850 μc. P(32)/kg showed the increase of Heinz's body either 30 minutes or 3 hours after the injection, and after 48 hours and 28 days respectively their values reached close to 1, 000‰ and continuously showing an intermediately progressive trend, they all died. The blood counts of capillary leucocytes in the case of the rabbit No.58 returned to normal 28 days after the injection, but the percentage of capillary leucocytes, the blood counts of erythrocytes, and the bone picture were still abnormal and radio-active substance could be recognized in the bone. Heinz's body, however, did not appear in the control injected with primary potassium phosphate. 4. Among the 6 rabbits suffering from acute X-ray radiation, and the five from chronic, three of the latter and all the acute cases revealed a progressive proclivity to the formation of Heinz's body before their death. en-copyright= kn-copyright= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=7-2 article-no= start-page=4389 end-page=4397 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590710 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Histochemical Studies on the Skeletal Muscle and Functional Differentiation of the Anterior Column Cells Part II. Histochemical study on the anterior column cells, considering from functional differentiation of skeletal muscle kn-title=骨格筋線維および脊髄前柱細胞の機能分化に関する組織化学的研究 第2編 骨格筋機能分化よりみた脊髄前柱細胞の組織化学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Many studies on functional differentiation of the spinal anterior column cells have been performed by Granit and other physiologists, but its histological appraisal has not been made yet. The author investigated various parts of the spinal cord of cats with glycogen staining, phosphorylase reaction and keto-enolic granula staining. The large cells of the lateral nuclei in the anterior column cell group of the cervical and lumbar enlargements had strongly positive phosphorylase reaction and more glycogen and keto-enolic granules, while in the thoracic anterior column or in the medial nuclei of the cervical and lumbar enlargements, the larger cell group was hardly seen and there were mostly the smaller cell groups with negative or extremely weak phosphorylase reaction, less glycogen and less keto-enolic granules. The author has stated in Part I that the white muscle fiber has more phosphorylase and less dehydrogenase, while the red muscle fiber has more dehydrogenase and less phosphorylase. From these facts as stated above, it is considered that the anterior column cells of the lateral nuclei of the cervical and lumbar enlargements innervating the muscles of the extremities with phasic movement are the larger ones and have different metabolic system from that of the smaller cell group of the thoracic anterior column or the medial nuclei innervating the muscles of trunk with tonic function. en-copyright= kn-copyright= en-aut-name=SaitoKunio en-aut-sei=Saito en-aut-mei=Kunio kn-aut-name=斎藤邦雄 kn-aut-sei=斎藤 kn-aut-mei=邦雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第1（陣内）外科教室 END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=11-12 article-no= start-page=1241 end-page=1251 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=199012 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Isointegral map of normal adults kn-title=健常成人の Isointegral Map (area map) の性差および年齢差の分析値 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Isointegral maps (area maps) were recorded for 262 normal adults aged 20 to 81, and sex and age differences in the maps were analyzed. Men showed significantly larger QRS, QRST and STT area maps than women in the region from the left anterior to the left lateral chest. Age differences in the STT and QRST area maps were observed in men but not in women: younger men had larger maps in the region of the left anterior chest when compared with older males. en-copyright= kn-copyright= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=1 ORCID= en-aut-name=MatsubaraKatashi en-aut-sei=Matsubara en-aut-mei=Katashi kn-aut-name=松原堅 kn-aut-sei=松原 kn-aut-mei=堅 aut-affil-num=2 ORCID= en-aut-name=YamanariHiroshi en-aut-sei=Yamanari en-aut-mei=Hiroshi kn-aut-name=山成洋 kn-aut-sei=山成 kn-aut-mei=洋 aut-affil-num=3 ORCID= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部臨床検査医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部臨床検査医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部臨床検査医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部臨床検査医学教室 en-keyword=isointegral map kn-keyword=isointegral map en-keyword=area map kn-keyword=area map en-keyword=健常者 kn-keyword=健常者 END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=3-4 article-no= start-page=319 end-page=323 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=199004 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of cardiac lipoma kn-title=Cardiac Lipomaの一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We reported a case of primary cardiac lipoma in a 74-year-old woman who had a 23-year history of cardiomegaly. The chest roentgenogram showed an enlargement of the cardiac silhouette. The electrocardiogram showed slight abnormalities including mild low voltage of R wave in V6 and flat T wave in V5 and V6. M-mode and cross-sectional echocardiography revealed a low echoic mass which mainly situated between left ventricular posterior wall and the pericardium. The left and right ventricular wall motion was not affected. Computed tomography of the heart revealed a large mass backward of the left ventricle and right side of the right atrium. The attenuation values of the mass ranged around-118HU and was compatible to lipoma. We diagnosed as a lipoma of the heart possibly arising from the pericardium. Computed tomography may be of use for a very specific diagnosis of cardiac lipoma. en-copyright= kn-copyright= en-aut-name=HasuiMasahiro en-aut-sei=Hasui en-aut-mei=Masahiro kn-aut-name=蓮井雅浩 kn-aut-sei=蓮井 kn-aut-mei=雅浩 aut-affil-num=1 ORCID= en-aut-name=MukouharaNaoki en-aut-sei=Mukouhara en-aut-mei=Naoki kn-aut-name=向原直木 kn-aut-sei=向原 kn-aut-mei=直木 aut-affil-num=2 ORCID= en-aut-name=MarutaniMorio en-aut-sei=Marutani en-aut-mei=Morio kn-aut-name=丸谷盛雄 kn-aut-sei=丸谷 kn-aut-mei=盛雄 aut-affil-num=3 ORCID= en-aut-name=OhbayashiNaotsugu en-aut-sei=Ohbayashi en-aut-mei=Naotsugu kn-aut-name=大林直嗣 kn-aut-sei=大林 kn-aut-mei=直嗣 aut-affil-num=4 ORCID= en-aut-name=ShrakiTeruo en-aut-sei=Shraki en-aut-mei=Teruo kn-aut-name=白木照夫 kn-aut-sei=白木 kn-aut-mei=照夫 aut-affil-num=5 ORCID= en-aut-name=UchidaShinji en-aut-sei=Uchida en-aut-mei=Shinji kn-aut-name=内田真司 kn-aut-sei=内田 kn-aut-mei=真司 aut-affil-num=6 ORCID= en-aut-name=IharaKeiko en-aut-sei=Ihara en-aut-mei=Keiko kn-aut-name=井原敬子 kn-aut-sei=井原 kn-aut-mei=敬子 aut-affil-num=7 ORCID= en-aut-name=TogawaJun-ichiro en-aut-sei=Togawa en-aut-mei=Jun-ichiro kn-aut-name=戸川潤一郎 kn-aut-sei=戸川 kn-aut-mei=潤一郎 aut-affil-num=8 ORCID= en-aut-name=YamanariHiroshi en-aut-sei=Yamanari en-aut-mei=Hiroshi kn-aut-name=山成洋 kn-aut-sei=山成 kn-aut-mei=洋 aut-affil-num=9 ORCID= en-aut-name=HinaKazuyoshi en-aut-sei=Hina en-aut-mei=Kazuyoshi kn-aut-name=日名一誠 kn-aut-sei=日名 kn-aut-mei=一誠 aut-affil-num=10 ORCID= en-aut-name=KusachiShozo en-aut-sei=Kusachi en-aut-mei=Shozo kn-aut-name=草地省蔵 kn-aut-sei=草地 kn-aut-mei=省蔵 aut-affil-num=11 ORCID= en-aut-name=TsujiTakao en-aut-sei=Tsuji en-aut-mei=Takao kn-aut-name=辻孝夫 kn-aut-sei=辻 kn-aut-mei=孝夫 aut-affil-num=12 ORCID= en-aut-name=MimaTsutomu en-aut-sei=Mima en-aut-mei=Tsutomu kn-aut-name=美馬敦 kn-aut-sei=美馬 kn-aut-mei=敦 aut-affil-num=13 ORCID= en-aut-name=MatsubaraKatashi en-aut-sei=Matsubara en-aut-mei=Katashi kn-aut-name=松原堅 kn-aut-sei=松原 kn-aut-mei=堅 aut-affil-num=14 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=15 ORCID= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=16 ORCID= en-aut-name=TaniHideki en-aut-sei=Tani en-aut-mei=Hideki kn-aut-name=谷秀樹 kn-aut-sei=谷 kn-aut-mei=秀樹 aut-affil-num=17 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部第一内科学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部臨床検査医学教室 affil-num=14 en-affil= kn-affil=岡山大学医学部臨床検査医学教室 affil-num=15 en-affil= kn-affil=岡山大学医学部臨床検査医学教室 affil-num=16 en-affil= kn-affil=岡山大学医学部臨床検査医学教室 affil-num=17 en-affil= kn-affil=川崎製鉄水島病院内科 en-keyword=Cardiac lipoma kn-keyword=Cardiac lipoma en-keyword=胸部CT kn-keyword=胸部CT en-keyword=心エコー kn-keyword=心エコー END start-ver=1.4 cd-journal=joma no-vol=122 cd-vols= no-issue=3 article-no= start-page=231 end-page=236 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20101201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of transverse colon cancer with remarkable extramural invasion to stomach and jejunum kn-title=壁外性に腫瘤を形成し胃・小腸浸潤を示した横行結腸癌の１例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 77-year-old woman was admitted to our hospital due to abdominal pain and body weight loss. A palpable mass the size of an infant's head was tender on palpation and identified as an epigastric lesion. Colonoscopic examination revealed stenosis of the transverse colon, although no intraluminal growth of the tumor was found. The histologic findings of the biopsy material were poorly differentiated and/or undifferentiated cells. Abdominal CT scan showed an irregular-shaped tumor with a diameter of 10cm invading the stomach and jejunum. We performed an operation under a diagnosis of extramurally growing cancer or malignant lymphoma of the colon. Partial resection of the transverse colon was done by distal gastrectomy and partial resection of the jejunum. Histologic examination of the operative specimens revealed moderately differentiated adenocarcinoma of the transverse colon, prominently proliferating into the surrounding tissues. The finding of a long stenotic lesion and extramural compression by colonography are characteristic of this tumor, based on a review of 43 literature reports in Japan. en-copyright= kn-copyright= en-aut-name=HamanoRyosuke en-aut-sei=Hamano en-aut-mei=Ryosuke kn-aut-name=濱野亮輔 kn-aut-sei=濱野 kn-aut-mei=亮輔 aut-affil-num=1 ORCID= en-aut-name=OtsukaShinya en-aut-sei=Otsuka en-aut-mei=Shinya kn-aut-name=大塚眞哉 kn-aut-sei=大塚 kn-aut-mei=眞哉 aut-affil-num=2 ORCID= en-aut-name=KimuraYuuji en-aut-sei=Kimura en-aut-mei=Yuuji kn-aut-name=木村裕司 kn-aut-sei=木村 kn-aut-mei=裕司 aut-affil-num=3 ORCID= en-aut-name=NishieManabu en-aut-sei=Nishie en-aut-mei=Manabu kn-aut-name=西江学 kn-aut-sei=西江 kn-aut-mei=学 aut-affil-num=4 ORCID= en-aut-name=TokunagaNaoyuki en-aut-sei=Tokunaga en-aut-mei=Naoyuki kn-aut-name=徳永尚之 kn-aut-sei=徳永 kn-aut-mei=尚之 aut-affil-num=5 ORCID= en-aut-name=MiyasouHideaki en-aut-sei=Miyasou en-aut-mei=Hideaki kn-aut-name=宮宗秀明 kn-aut-sei=宮宗 kn-aut-mei=秀明 aut-affil-num=6 ORCID= en-aut-name=TsunemituYousuke en-aut-sei=Tsunemitu en-aut-mei=Yousuke kn-aut-name=常光洋輔 kn-aut-sei=常光 kn-aut-mei=洋輔 aut-affil-num=7 ORCID= en-aut-name=InagakiMasaru en-aut-sei=Inagaki en-aut-mei=Masaru kn-aut-name=稲垣優 kn-aut-sei=稲垣 kn-aut-mei=優 aut-affil-num=8 ORCID= en-aut-name=IwakawaKazuhide en-aut-sei=Iwakawa en-aut-mei=Kazuhide kn-aut-name=岩川和秀 kn-aut-sei=岩川 kn-aut-mei=和秀 aut-affil-num=9 ORCID= en-aut-name=IwagakiHiromi en-aut-sei=Iwagaki en-aut-mei=Hiromi kn-aut-name=岩垣博巳 kn-aut-sei=岩垣 kn-aut-mei=博巳 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=2 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=3 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=4 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=5 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=6 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=7 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=8 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=9 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=10 en-affil= kn-affil=国立病院機構福山医療センター　外科 en-keyword=大腸癌 (colon cancer) kn-keyword=大腸癌 (colon cancer) en-keyword=壁外性発育 (extraluminal growth) kn-keyword=壁外性発育 (extraluminal growth) END start-ver=1.4 cd-journal=joma no-vol=122 cd-vols= no-issue=3 article-no= start-page=225 end-page=229 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20101201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Usefulness of the waterless method for surgical hand washing：A comparison with the conventional scrub method kn-title=手術時手洗いにおける従来法とツーステージ・サージカルスクラブ法，ウォーターレス法の比較について en-subtitle= kn-subtitle= en-abstract= kn-abstract=To evaluate the usefulness of the waterless hand washing method for surgical anti-sepsis, we conducted a microbial sampling study, comparing it to a conventional surgical scrub method. A total of 18 operating-room nurses were undertaking the following three-hand washing protocols : scrubbing with blushes using 4w/v% chlorhexidine gluconate (CHG) and also rubbing with CHG, followed by application of a 0.2w/v% CHG with ethanol (HS) preparation. (conventional method); rubbing with CHG and application of HS (two-stage surgical scrub method; TSS); rubbing with anti-septic soap and application of HS (waterless method; WL). Microbial sampling was conducted after hand washing using the glove juice method. No statistically significant differences in bacterial numbers were found among these three methods. The number of bacterially positive subjects was significantly higher in the conventional method than the TSS method. These results indicate that there are adverse effects of blush-scrubbing, as the detected bacteria were related to normal skin flora. As such, the WL method for hand anti-sepsis appears to be equivalent to the conventional surgical scrubbing method in terms of microbial detection. The WL method should therefore be introduced as a standard hand anti-sepsis method at the time of surgery because it is cost-effective as well as time-efficient. en-copyright= kn-copyright= en-aut-name=KobayashiYuka en-aut-sei=Kobayashi en-aut-mei=Yuka kn-aut-name=小林由佳 kn-aut-sei=小林 kn-aut-mei=由佳 aut-affil-num=1 ORCID= en-aut-name=YamadaMisa en-aut-sei=Yamada en-aut-mei=Misa kn-aut-name=山田美佐 kn-aut-sei=山田 kn-aut-mei=美佐 aut-affil-num=2 ORCID= en-aut-name=FujiiHiromi en-aut-sei=Fujii en-aut-mei=Hiromi kn-aut-name=藤井裕美 kn-aut-sei=藤井 kn-aut-mei=裕美 aut-affil-num=3 ORCID= en-aut-name=KoYukiko en-aut-sei=Ko en-aut-mei=Yukiko kn-aut-name=甲由紀子 kn-aut-sei=甲 kn-aut-mei=由紀子 aut-affil-num=4 ORCID= en-aut-name=UotaniIzumi en-aut-sei=Uotani en-aut-mei=Izumi kn-aut-name=魚谷いづみ kn-aut-sei=魚谷 kn-aut-mei=いづみ aut-affil-num=5 ORCID= en-aut-name=TamotoMariko en-aut-sei=Tamoto en-aut-mei=Mariko kn-aut-name=田本真理子 kn-aut-sei=田本 kn-aut-mei=真理子 aut-affil-num=6 ORCID= en-aut-name=NadaMasako en-aut-sei=Nada en-aut-mei=Masako kn-aut-name=名田正子 kn-aut-sei=名田 kn-aut-mei=正子 aut-affil-num=7 ORCID= en-aut-name=MuraiHiroyuki en-aut-sei=Murai en-aut-mei=Hiroyuki kn-aut-name=村井裕之 kn-aut-sei=村井 kn-aut-mei=裕之 aut-affil-num=8 ORCID= en-aut-name=KadoEi en-aut-sei=Kado en-aut-mei=Ei kn-aut-name=角英 kn-aut-sei=角 kn-aut-mei=英 aut-affil-num=9 ORCID= en-aut-name=IwagakiHiromi en-aut-sei=Iwagaki en-aut-mei=Hiromi kn-aut-name=岩垣博巳 kn-aut-sei=岩垣 kn-aut-mei=博巳 aut-affil-num=10 ORCID= en-aut-name=TomodaJun en-aut-sei=Tomoda en-aut-mei=Jun kn-aut-name=友田純 kn-aut-sei=友田 kn-aut-mei=純 aut-affil-num=11 ORCID= en-aut-name=SaitoShinya en-aut-sei=Saito en-aut-mei=Shinya kn-aut-name=斎藤信也 kn-aut-sei=斎藤 kn-aut-mei=信也 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=国立病院機構福山医療センター　看護部 affil-num=2 en-affil= kn-affil=国立病院機構福山医療センター　看護部 affil-num=3 en-affil= kn-affil=国立病院機構福山医療センター　看護部 affil-num=4 en-affil= kn-affil=国立病院機構福山医療センター　看護部 affil-num=5 en-affil= kn-affil=国立病院機構福山医療センター　看護部 affil-num=6 en-affil= kn-affil=国立病院機構福山医療センター　看護部 affil-num=7 en-affil= kn-affil=国立病院機構福山医療センター　看護部 affil-num=8 en-affil= kn-affil=国立病院機構福山医療センター　臨床検査部 affil-num=9 en-affil= kn-affil=国立病院機構福山医療センター　薬剤部 affil-num=10 en-affil= kn-affil=国立病院機構福山医療センター　外科 affil-num=11 en-affil= kn-affil=国立病院機構福山医療センター　内科 affil-num=12 en-affil= kn-affil=岡山大学大学院保健学研究科　感染管理学 en-keyword=手洗い (hand washing) kn-keyword=手洗い (hand washing) en-keyword=手指消毒 (hand antisepsis) kn-keyword=手指消毒 (hand antisepsis) en-keyword=ツーステージ・サージカルスクラブ法 (surgical scrub method) kn-keyword=ツーステージ・サージカルスクラブ法 (surgical scrub method) en-keyword=ウォーターレス法 (waterless method) kn-keyword=ウォーターレス法 (waterless method) en-keyword=手術 (surgery) kn-keyword=手術 (surgery) END start-ver=1.4 cd-journal=joma no-vol=6 cd-vols= no-issue= article-no= start-page=84 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19841101 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=編集後記 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SaitoSeiki en-aut-sei=Saito en-aut-mei=Seiki kn-aut-name=斎藤清機 kn-aut-sei=斎藤 kn-aut-mei=清機 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=10 cd-vols= no-issue= article-no= start-page=72 end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=19881201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=編集後記 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SaitoSeiki en-aut-sei=Saito en-aut-mei=Seiki kn-aut-name=斎藤清機 kn-aut-sei=斎藤 kn-aut-mei=清機 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=16 cd-vols= no-issue= article-no= start-page=21 end-page=25 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=199909 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=DEVELOPMENT OF "Luftain -Tg" AS A MICROISOLATION CAGE SYSTEM kn-title=ルフテンTgの開発 en-subtitle= kn-subtitle= en-abstract=Tgマウスの飼育に適し､かつ､飼育作業性の良いラックの開発を行った｡バスタブ型ケージを吊り式とし､天井／吊りレール／背面側塞ぎ板により上方3方を閉鎖しケージからの排気出口は上前面のケージ鍔上のみとした｡ケージ-の上後方からの直接給気とケージからの排気の流れは架台前面をエアカーテンで制御し､架台後方より排気することによりケージ内外の汚染の伝播を防止する機構になっており､コンピューター･シミュレーション及び気流可視化試験によりその効果が確認できた｡ kn-abstract=Developed "Luftain Tg" to include cage and luck for the breeding, nowadays an experiment increases as exchanging it digest gene set, and breeding, experiment of Transgenic mouse (following Tg mouse) increases. Doesn't exit the front of luck to outside as giving and doing a mind directly to cage inside, as a ceremony as hanging bathtub type cage-we controlled with a curtain and developed a system to defend from an expansion of cage inside and outside contamination. Again, for flowing of these air computer simulation even though were able to confirm it. en-copyright= kn-copyright= en-aut-name=SaitohM. en-aut-sei=Saitoh en-aut-mei=M. kn-aut-name=斎藤正信 kn-aut-sei=斎藤 kn-aut-mei=正信 aut-affil-num=1 ORCID= en-aut-name=OhshiroM. en-aut-sei=Ohshiro en-aut-mei=M. kn-aut-name=大城匡豊 kn-aut-sei=大城 kn-aut-mei=匡豊 aut-affil-num=2 ORCID= en-aut-name=ShiraganeK. en-aut-sei=Shiragane en-aut-mei=K. kn-aut-name=銀一之 kn-aut-sei=銀 kn-aut-mei=一之 aut-affil-num=3 ORCID= en-aut-name=HashizumeT. en-aut-sei=Hashizume en-aut-mei=T. kn-aut-name=橋詰俊雄 kn-aut-sei=橋詰 kn-aut-mei=俊雄 aut-affil-num=4 ORCID= en-aut-name=KurabayashiYuzuru en-aut-sei=Kurabayashi en-aut-mei=Yuzuru kn-aut-name=倉林譲 kn-aut-sei=倉林 kn-aut-mei=譲 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=大氣社 affil-num=2 en-affil= kn-affil=大氣社 affil-num=3 en-affil= kn-affil=白銀工業 affil-num=4 en-affil= kn-affil=白銀工業 affil-num=5 en-affil= kn-affil=岡山大学医学部附属動物実験施設 END start-ver=1.4 cd-journal=joma no-vol=122 cd-vols= no-issue=1 article-no= start-page=67 end-page=71 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Japanese guideline for management of cervical spondylotis myelopathy kn-title=頚椎症性脊髄症の診療ガイドライン en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TanakaMasato en-aut-sei=Tanaka en-aut-mei=Masato kn-aut-name=田中雅人 kn-aut-sei=田中 kn-aut-mei=雅人 aut-affil-num=1 ORCID= en-aut-name=SugimotoYoshihisa en-aut-sei=Sugimoto en-aut-mei=Yoshihisa kn-aut-name=杉本佳久 kn-aut-sei=杉本 kn-aut-mei=佳久 aut-affil-num=2 ORCID= en-aut-name=MisawaHaruo en-aut-sei=Misawa en-aut-mei=Haruo kn-aut-name=三澤治夫 kn-aut-sei=三澤 kn-aut-mei=治夫 aut-affil-num=3 ORCID= en-aut-name=TakahataTomohiro en-aut-sei=Takahata en-aut-mei=Tomohiro kn-aut-name=高畑智宏 kn-aut-sei=高畑 kn-aut-mei=智宏 aut-affil-num=4 ORCID= en-aut-name=OzakiToshifumi en-aut-sei=Ozaki en-aut-mei=Toshifumi kn-aut-name=尾ｱ敏文 kn-aut-sei=尾ｱ kn-aut-mei=敏文 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　整形外科学 END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=5-1 article-no= start-page=2025 end-page=2031 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590415 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Direction and arrangement of cutting lines of cerebral dura mater, pleura and peritoneum in human body. Part 1. Direction and arrangment of cutting lines of cerebral dura mater in human body kn-title=人の脳硬膜,胸膜,腹膜における割線の配列に関する研究 第1編 人の脳硬膜の割線の配列について en-subtitle= kn-subtitle= en-abstract= kn-abstract=In the vault part, the cutting lines of the dura lay in a direction from anterolatero-inferior to postero-supero-medial in the outer layer but in the inner layer lay in that from postero-latero-inferior to antero-supero-medial. Thus they are crossing over each other and their dicrections were bilaterally symmetrical. The directions of the cutting lines in other parts, such as cerebral falx, anterior, middle and posterior fossas and clivus, were also investigated and precisely reported. en-copyright= kn-copyright= en-aut-name=SaitoWaichiro en-aut-sei=Saito en-aut-mei=Waichiro kn-aut-name=斎藤和一郎 kn-aut-sei=斎藤 kn-aut-mei=和一郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第1外科教室 END start-ver=1.4 cd-journal=joma no-vol=89 cd-vols= no-issue=11-12 article-no= start-page=1569 end-page=1576 dt-received= dt-revised= dt-accepted= dt-pub-year=1977 dt-pub=19771230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Exercise test in atrial fibrillation kn-title=心房細動とMaster二重運動負荷試験 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The exercise electrocardiogram was studied in the patients with atrial fibrillation who were presumably free of hyperthyroidism, severe pulmonary disease or valvular disease. Thirty-one patients with atrial fibrillation, 25 male and 6 female, were subjected to a double Master's two-step exercise test. Seventeen out of thirty-one patients (54.8%) had abnormal electrocardiograms (positive test) according to our criteria after the double two-step test. Heart rate responding to the exercise increased much more than controls reported previously form our laboratory. It was assumed that in atrial fibrillation, an abnormally excess response of heart rate to exercise caused a marked rise in myocardial oxygen demands according to an increase in cardiac work and a decrease in effective coronary perfusion time. Furthermore, atrial fibrillation, probably absolutely irregular ventricular rate, might decrease coronary flow reserve responding to increase in oxygen demand. These suggest that abnormal hemodynamic responses to the exercise result in positive test even in the cases without coronary artery disease. en-copyright= kn-copyright= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=1 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=2 ORCID= en-aut-name=UedaMinoru en-aut-sei=Ueda en-aut-mei=Minoru kn-aut-name=上田稔 kn-aut-sei=上田 kn-aut-mei=稔 aut-affil-num=3 ORCID= en-aut-name=OginoYasuhiro en-aut-sei=Ogino en-aut-mei=Yasuhiro kn-aut-name=荻野泰洋 kn-aut-sei=荻野 kn-aut-mei=泰洋 aut-affil-num=4 ORCID= en-aut-name=KusuharaShunichi en-aut-sei=Kusuhara en-aut-mei=Shunichi kn-aut-name=楠原俊一 kn-aut-sei=楠原 kn-aut-mei=俊一 aut-affil-num=5 ORCID= en-aut-name=YoshidaHideki en-aut-sei=Yoshida en-aut-mei=Hideki kn-aut-name=吉田英紀 kn-aut-sei=吉田 kn-aut-mei=英紀 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一内科教室 END start-ver=1.4 cd-journal=joma no-vol=92 cd-vols= no-issue=9-10 article-no= start-page=1045 end-page=1053 dt-received= dt-revised= dt-accepted= dt-pub-year=1980 dt-pub=19801030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Paroxysmal atrial fibrillation kn-title=発作性心房細動について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Out of 60 patients of transient atrial fibrillation including a case followed up for 12 years, 51 cases with unknown etiology or due to ischemic heart disease were studied in this paper. 1. Transient atrial fibrillation tends to induce cerebrovascular accidents although no direct relationship between the two was detected. 2. Transient atrial fibrillation combines frequently with sick sinus syndrome, especially with sinus bradycardia. 3. The cases combined with sick sinus syndrome have not only cardiac problems but also a higher risk of cerebrovascular accidents. 4. At the onset of atrial fibrillation, many cases complain of pollakisuria as well as other symptoms reported previously. 5. No apparent causes for atrial fibrillation was found in more than half of our cases. However, most cases had something to do with physical and/or mental stress. en-copyright= kn-copyright= en-aut-name=MaeRitsuo en-aut-sei=Mae en-aut-mei=Ritsuo kn-aut-name=前律夫 kn-aut-sei=前 kn-aut-mei=律夫 aut-affil-num=1 ORCID= en-aut-name=NagahanaHaruki en-aut-sei=Nagahana en-aut-mei=Haruki kn-aut-name=長花晴樹 kn-aut-sei=長花 kn-aut-mei=晴樹 aut-affil-num=2 ORCID= en-aut-name=MashimaKozo en-aut-sei=Mashima en-aut-mei=Kozo kn-aut-name=間嶋行造 kn-aut-sei=間嶋 kn-aut-mei=行造 aut-affil-num=3 ORCID= en-aut-name=FujiiAkinobu en-aut-sei=Fujii en-aut-mei=Akinobu kn-aut-name=藤井章伸 kn-aut-sei=藤井 kn-aut-mei=章伸 aut-affil-num=4 ORCID= en-aut-name=IhoriyaKazuo en-aut-sei=Ihoriya en-aut-mei=Kazuo kn-aut-name=庵谷和夫 kn-aut-sei=庵谷 kn-aut-mei=和夫 aut-affil-num=5 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=6 ORCID= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第一内科教室 en-keyword=発作性心房細動 kn-keyword=発作性心房細動 en-keyword=Sick Sinus Syndrome kn-keyword=Sick Sinus Syndrome en-keyword=脳血管障害 kn-keyword=脳血管障害 en-keyword=頻尿 kn-keyword=頻尿 END start-ver=1.4 cd-journal=joma no-vol=92 cd-vols= no-issue=9-10 article-no= start-page=1033 end-page=1044 dt-received= dt-revised= dt-accepted= dt-pub-year=1980 dt-pub=19801030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Tricuspid incompetence due to non-penetrating trauma with a congenital left pleuro-pericardial defect kn-title=左側心外膜欠損を伴つた外傷性三尖弁閉鎖不全症の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We report a case of traumatic rupture of the chordae tendineae of the tricuspid valve with a congenital left pleuro-pericardial defect. The chest X ray film revealed a large cardiac silhouette which protruded to the left. Echocardiographic findings were: 1) large right ventricle and paradoxical septal motion 2) tricuspid regurgitatin which was recognized by contrast echocardiography 3) small left ventricle. This case also had a characteristic finding of systolic fine oscillation on the posterior tricuspid leaflet. Computed tomograms explained the discrepancy (protrusion to the left in chest X ray and small left ventricle): Computed tomograms of the heart revealed an enlarged right atrium and right ventricle associated with prominent clockwise rotation of the heart. Open heart surgery, performed successfully 16 years after the non-penetrating trauma, revealed the congenital pericardial defect which produced the findings of computed tomogram. en-copyright= kn-copyright= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=1 ORCID= en-aut-name=UedaMinoru en-aut-sei=Ueda en-aut-mei=Minoru kn-aut-name=上田稔 kn-aut-sei=上田 kn-aut-mei=稔 aut-affil-num=2 ORCID= en-aut-name=YamadaNobuyuki en-aut-sei=Yamada en-aut-mei=Nobuyuki kn-aut-name=山田信行 kn-aut-sei=山田 kn-aut-mei=信行 aut-affil-num=3 ORCID= en-aut-name=NagahanaHaruki en-aut-sei=Nagahana en-aut-mei=Haruki kn-aut-name=長花晴樹 kn-aut-sei=長花 kn-aut-mei=晴樹 aut-affil-num=4 ORCID= en-aut-name=IhoriyaKazuo en-aut-sei=Ihoriya en-aut-mei=Kazuo kn-aut-name=庵谷和夫 kn-aut-sei=庵谷 kn-aut-mei=和夫 aut-affil-num=5 ORCID= en-aut-name=MashimaKozo en-aut-sei=Mashima en-aut-mei=Kozo kn-aut-name=間嶋行造 kn-aut-sei=間嶋 kn-aut-mei=行造 aut-affil-num=6 ORCID= en-aut-name=FujiiAkinobu en-aut-sei=Fujii en-aut-mei=Akinobu kn-aut-name=藤井章伸 kn-aut-sei=藤井 kn-aut-mei=章伸 aut-affil-num=7 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=8 ORCID= en-aut-name=TeramotoShigeru en-aut-sei=Teramoto en-aut-mei=Shigeru kn-aut-name=寺本滋 kn-aut-sei=寺本 kn-aut-mei=滋 aut-affil-num=9 ORCID= en-aut-name=NawaKiyoto en-aut-sei=Nawa en-aut-mei=Kiyoto kn-aut-name=名和清人 kn-aut-sei=名和 kn-aut-mei=清人 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=9 en-affil= kn-affil=岡山大学医学部第二外科教室 affil-num=10 en-affil= kn-affil=岡山大学医学部第二外科教室 en-keyword=非穿通性心外傷 kn-keyword=非穿通性心外傷 en-keyword=三尖弁閉鎖不全症 kn-keyword=三尖弁閉鎖不全症 en-keyword=心胸膜欠損 kn-keyword=心胸膜欠損 en-keyword=心エコー図と胸部CT kn-keyword=心エコー図と胸部CT END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=11-12 article-no= start-page=1067 end-page=1075 dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19821230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical studies on bronchial asthma Part 2. Late skin and bronchial responses to allergens in patients with bronchial asthma kn-title=気管支喘息に関する臨床的研究 第2編 気管支喘息における皮膚および気管支の遅発型反応について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Late skin and bronchial responses to house dust and Candida allergens were examined in 301 patients with bronchial asthma. The results were as follows: 1) Late skin and bronchial responses to house dust extract were related to serum IgE levels, basophil reactivity to anti-IgE and RAST score of house dust, 2) Late skin and bronchial responses to Candida extract were related to precipitating antibodies to Candida, although these responses were not related to serum IgE levels and basophil reactivity to anti-human IgE. These results suggest that the late response to house dust allergen was mainly elicited by IgE-mediated type T allergic reaction and that the late response to Candida allergen was in part elicited by precipitating antibody-mediated type V allergic reaction. en-copyright= kn-copyright= en-aut-name=SaitoKatsuyoshi en-aut-sei=Saito en-aut-mei=Katsuyoshi kn-aut-name=斎藤勝剛 kn-aut-sei=斎藤 kn-aut-mei=勝剛 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第2内科 en-keyword=気管支喘息 kn-keyword=気管支喘息 en-keyword=皮膚遅発型反応 kn-keyword=皮膚遅発型反応 en-keyword=気管支遅発型反応 kn-keyword=気管支遅発型反応 en-keyword=沈降抗体 kn-keyword=沈降抗体 END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=11-12 article-no= start-page=1059 end-page=1066 dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19821230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical studies on bronchial asthma Part 1. Appearance of basophilic leucocytes in sputum of patients with bronchial asthma. kn-title=気管支喘息に関する臨床的研究 第1編 気管支喘息における喀痰中の好塩基球について en-subtitle= kn-subtitle= en-abstract= kn-abstract=A total of 103 samples of sputum from 20 patients with bronchial asthma were examined for appearance of basophils and eosinophils. The results are as follows: 1) Basophilic leucocytes were found in the sputum of patients with bronchial asthma. 2) Basophils appeared in sputum during asthma attacks and disappeared during nonattack stages. 3) The number of basophils in sputum tended to increase at the end of attack stages. 4) High incidence of basophils in sputum was observed in asthmatic patients with low serum IgE levels. 5) Appearance of basophils in sputum was accompanied with that of eosinophils. 6) Appearance of basophils in sputum was related to the number of peripheral basophils, but not to the daily volume of sputum. These results suggest that basophils migrate from the blood stream into bronchial tissues and appear in sputum during attack stages of bronchial asthma. en-copyright= kn-copyright= en-aut-name=SaitoKatsuyoshi en-aut-sei=Saito en-aut-mei=Katsuyoshi kn-aut-name=斎藤勝剛 kn-aut-sei=斎藤 kn-aut-mei=勝剛 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第2内科 en-keyword=気管支喘息 kn-keyword=気管支喘息 en-keyword=喀痰中の好塩基球 kn-keyword=喀痰中の好塩基球 en-keyword=好塩基球 kn-keyword=好塩基球 END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=11-12 article-no= start-page=1051 end-page=1057 dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19821230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Echocardiographic study of school children kn-title=学校心臓検診 (二次検診) の心エコー図所見 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We studied the echocardiograms of 243 school children who needed further examination of the heart beyond electrocardiography, auscultation, chest X-ray and/or medical history. 1. Thirty of them showed mitral valve prolapse including two with Marfan's syndrome, one with arrythmias exaggerated by physical exercise and a case with left ventricular volume overloading. 2. Five of eight patients who were suspected to suffer from a atrial septal defect by electrocardiography and auscultation showed right ventricular volume overload echocardiographically. In four of the five, an intracardiac shunt at the atrial level was confirmed by contrast echocardiography. 3. One case with right ventricular hypertrophy as determined by electrocardiography showed right ventricular pressure stress echocardiographically. He was diagnosed as having primary pulmonary hypertension by cardiac catheterization. 4. A ventricular septal defect and patent ductus arteriosus were diagnosed in six cases by auscultation or phonocardiography, but not so by echocardiogaraphy. Echocardiography as a secondary examination is not only diagnostic in itself but also is beneficial in determining whether or not further examination (cardiac catheterization) is needed. en-copyright= kn-copyright= en-aut-name=UedaMinoru en-aut-sei=Ueda en-aut-mei=Minoru kn-aut-name=上田稔 kn-aut-sei=上田 kn-aut-mei=稔 aut-affil-num=1 ORCID= en-aut-name=YamadaNobuyuki en-aut-sei=Yamada en-aut-mei=Nobuyuki kn-aut-name=山田信行 kn-aut-sei=山田 kn-aut-mei=信行 aut-affil-num=2 ORCID= en-aut-name=UchidaToshiaki en-aut-sei=Uchida en-aut-mei=Toshiaki kn-aut-name=内田俊明 kn-aut-sei=内田 kn-aut-mei=俊明 aut-affil-num=3 ORCID= en-aut-name=IhoriyaKazuo en-aut-sei=Ihoriya en-aut-mei=Kazuo kn-aut-name=庵谷和夫 kn-aut-sei=庵谷 kn-aut-mei=和夫 aut-affil-num=4 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=5 ORCID= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=6 ORCID= en-aut-name=NishiyamaOsamu en-aut-sei=Nishiyama en-aut-mei=Osamu kn-aut-name=西山修 kn-aut-sei=西山 kn-aut-mei=修 aut-affil-num=7 ORCID= en-aut-name=KitaToshimasa en-aut-sei=Kita en-aut-mei=Toshimasa kn-aut-name=喜多利正 kn-aut-sei=喜多 kn-aut-mei=利正 aut-affil-num=8 ORCID= en-aut-name=TanetaniSetsuro en-aut-sei=Tanetani en-aut-mei=Setsuro kn-aut-name=種谷節郎 kn-aut-sei=種谷 kn-aut-mei=節郎 aut-affil-num=9 ORCID= en-aut-name=SakaiYutaka en-aut-sei=Sakai en-aut-mei=Yutaka kn-aut-name=堺裕 kn-aut-sei=堺 kn-aut-mei=裕 aut-affil-num=10 ORCID= en-aut-name=SakakibaraHiroshi en-aut-sei=Sakakibara en-aut-mei=Hiroshi kn-aut-name=榊原宏 kn-aut-sei=榊原 kn-aut-mei=宏 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=7 en-affil= kn-affil=榊原十全病院 affil-num=8 en-affil= kn-affil=榊原十全病院 affil-num=9 en-affil= kn-affil=榊原十全病院 affil-num=10 en-affil= kn-affil=榊原十全病院 affil-num=11 en-affil= kn-affil=榊原十全病院 en-keyword=学校検診 kn-keyword=学校検診 en-keyword=心エコー図 kn-keyword=心エコー図 en-keyword=僧帽弁逸脱 kn-keyword=僧帽弁逸脱 END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=1-2 article-no= start-page=25 end-page=35 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19790228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A cardiovascular epidemiologic survey in three different areas of Okayama Prefecture (Sakuto-cho, Sanyo-cho and Osafune-cho) during the period from 1966 to 1976 III. Cerebro-cardiovascular risk factors kn-title=岡山県の三地区(作東町,山陽町,長船町)の循環器疫学調査(1966〜1976) 第3報 脳・心事故と危険因子との関係 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A cardiovascular epidemiologic survey has been carried out in three different areas (Sakuto-cho, Sanyo-cho and Osafune-cho) of Okayama Prefecture since 1966. Cerebro-cardiovascular risk factors were investigated using data obtained in the first examination. The following results were obtained: 1. Sixty-six cerebro-cardiovascular accidents (CCA) occurred in 1906 subjects over a ten year period (1966 to 1976); of these, 33 were cerebrovascular accidents (CVA) and 33 were cardiac accidents. The prevalence rate was the highest in Sakuto-cho and the lowest in Sanyo-cho. This reflected the degree of control of blood pressure. 2. Cardiovascular accidents had a slightly higher prevalence rate in females than in males. 3. CCA in males showed a positive correlation to increase in relative body weight. In females, there was no significant relationship between CCA and relative body weight. 4. Compared to subjects with normal urinalysis, the prevalence rate of CCA was 1.7 in subjects with proteinuria and 3.2 in those with glucosuria. 5. CCA occurred more frequently in both the systolic hypertension group and the group with combined systolic and diastolic hypertension. en-copyright= kn-copyright= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=1 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=2 ORCID= en-aut-name=UedaMinoru en-aut-sei=Ueda en-aut-mei=Minoru kn-aut-name=上田稔 kn-aut-sei=上田 kn-aut-mei=稔 aut-affil-num=3 ORCID= en-aut-name=OginoYasuhiro en-aut-sei=Ogino en-aut-mei=Yasuhiro kn-aut-name=荻野泰洋 kn-aut-sei=荻野 kn-aut-mei=泰洋 aut-affil-num=4 ORCID= en-aut-name=KusuharaShunichi en-aut-sei=Kusuhara en-aut-mei=Shunichi kn-aut-name=楠原俊一 kn-aut-sei=楠原 kn-aut-mei=俊一 aut-affil-num=5 ORCID= en-aut-name=YoshidaHidenori en-aut-sei=Yoshida en-aut-mei=Hidenori kn-aut-name=吉田英紀 kn-aut-sei=吉田 kn-aut-mei=英紀 aut-affil-num=6 ORCID= en-aut-name=KawasakiTomoko en-aut-sei=Kawasaki en-aut-mei=Tomoko kn-aut-name=川崎智子 kn-aut-sei=川崎 kn-aut-mei=智子 aut-affil-num=7 ORCID= en-aut-name=MisayakaMinoru en-aut-sei=Misayaka en-aut-mei=Minoru kn-aut-name=宮阪実 kn-aut-sei=宮阪 kn-aut-mei=実 aut-affil-num=8 ORCID= en-aut-name=YoshiokaNobuhiko en-aut-sei=Yoshioka en-aut-mei=Nobuhiko kn-aut-name=吉岡信彦 kn-aut-sei=吉岡 kn-aut-mei=信彦 aut-affil-num=9 ORCID= en-aut-name=IkenagaToyotake en-aut-sei=Ikenaga en-aut-mei=Toyotake kn-aut-name=生長豊健 kn-aut-sei=生長 kn-aut-mei=豊健 aut-affil-num=10 ORCID= en-aut-name=KusachiShowzo en-aut-sei=Kusachi en-aut-mei=Showzo kn-aut-name=草地省藏 kn-aut-sei=草地 kn-aut-mei=省藏 aut-affil-num=11 ORCID= en-aut-name=SogoTaiji en-aut-sei=Sogo en-aut-mei=Taiji kn-aut-name=十河泰司 kn-aut-sei=十河 kn-aut-mei=泰司 aut-affil-num=12 ORCID= en-aut-name=YamadaNobuyuki en-aut-sei=Yamada en-aut-mei=Nobuyuki kn-aut-name=山田信行 kn-aut-sei=山田 kn-aut-mei=信行 aut-affil-num=13 ORCID= en-aut-name=NishiyamaOsamu en-aut-sei=Nishiyama en-aut-mei=Osamu kn-aut-name=西山修 kn-aut-sei=西山 kn-aut-mei=修 aut-affil-num=14 ORCID= en-aut-name=YasuharaKoichiro en-aut-sei=Yasuhara en-aut-mei=Koichiro kn-aut-name=安原耕一郎 kn-aut-sei=安原 kn-aut-mei=耕一郎 aut-affil-num=15 ORCID= en-aut-name=HisamatsuMitsuo en-aut-sei=Hisamatsu en-aut-mei=Mitsuo kn-aut-name=久松三生 kn-aut-sei=久松 kn-aut-mei=三生 aut-affil-num=16 ORCID= en-aut-name=NukadaKaname en-aut-sei=Nukada en-aut-mei=Kaname kn-aut-name=額田要 kn-aut-sei=額田 kn-aut-mei=要 aut-affil-num=17 ORCID= en-aut-name=ImadaKakuro en-aut-sei=Imada en-aut-mei=Kakuro kn-aut-name=今田格郎 kn-aut-sei=今田 kn-aut-mei=格郎 aut-affil-num=18 ORCID= en-aut-name=HirataTakako en-aut-sei=Hirata en-aut-mei=Takako kn-aut-name=平田孝子 kn-aut-sei=平田 kn-aut-mei=孝子 aut-affil-num=19 ORCID= en-aut-name=KasuYoshiko en-aut-sei=Kasu en-aut-mei=Yoshiko kn-aut-name=嘉数佳子 kn-aut-sei=嘉数 kn-aut-mei=佳子 aut-affil-num=20 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=5 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=6 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=9 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=10 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=11 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=12 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=13 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=14 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=15 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=16 en-affil= kn-affil=岡山大学医学部第一内科教室 affil-num=17 en-affil= kn-affil=岡山県衛生部 affil-num=18 en-affil= kn-affil=岡山県衛生部 affil-num=19 en-affil= kn-affil=岡山県衛生部 affil-num=20 en-affil= kn-affil=岡山県衛生部 en-keyword=高血圧 kn-keyword=高血圧 en-keyword=性 kn-keyword=性 en-keyword=尿糖 kn-keyword=尿糖 en-keyword=尿蛋白 kn-keyword=尿蛋白 en-keyword=肥満 kn-keyword=肥満 END start-ver=1.4 cd-journal=joma no-vol=96 cd-vols= no-issue=1-2 article-no= start-page=189 end-page=196 dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19840228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of primary systemic amyloidosis with sinus node dysfunction and conduction defects. kn-title=洞機能不全と多彩な伝導障害を呈した原発性アミロイドーシスの一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A case of primary systemic amyloidosis with various ECG abnormalities is reported. The ECG on admission showed low voltage in limb leads, right axis deviation, small q wave in leads I and aVL and QS configulation in V(1) through V(2). Conduction disturbances were observed in intra-atrial, A-V junctional and intraventricular conductions with frequent sinus arrest associated by A-V junctional escape beats. The heart sometimes fell into complete A-V block, infrequently with supernormal conduction. In spite of markedly abnormal ECG findings, amyloid infiltration in the mycoardium, His-bundle, A-V node and other discrepancies were minimum. en-copyright= kn-copyright= en-aut-name=FujiiAkinobu en-aut-sei=Fujii en-aut-mei=Akinobu kn-aut-name=藤井章伸 kn-aut-sei=藤井 kn-aut-mei=章伸 aut-affil-num=1 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=2 ORCID= en-aut-name=OhnishiShigeaki en-aut-sei=Ohnishi en-aut-mei=Shigeaki kn-aut-name=大西茂明 kn-aut-sei=大西 kn-aut-mei=茂明 aut-affil-num=3 ORCID= en-aut-name=AbeYukinori en-aut-sei=Abe en-aut-mei=Yukinori kn-aut-name=安部行弘 kn-aut-sei=安部 kn-aut-mei=行弘 aut-affil-num=4 ORCID= en-aut-name=YoshidaHidenori en-aut-sei=Yoshida en-aut-mei=Hidenori kn-aut-name=吉田英紀 kn-aut-sei=吉田 kn-aut-mei=英紀 aut-affil-num=5 ORCID= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=6 ORCID= en-aut-name=NagashimaHideo en-aut-sei=Nagashima en-aut-mei=Hideo kn-aut-name=長島秀夫 kn-aut-sei=長島 kn-aut-mei=秀夫 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=岡山大学 affil-num=6 en-affil= kn-affil=岡山大学 affil-num=7 en-affil= kn-affil=岡山大学 en-keyword=原発性アミロイドーシス kn-keyword=原発性アミロイドーシス en-keyword=洞機能不全 kn-keyword=洞機能不全 en-keyword=房室伝導障害 kn-keyword=房室伝導障害 END start-ver=1.4 cd-journal=joma no-vol=100 cd-vols= no-issue=1-2 article-no= start-page=31 end-page=36 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=1988 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of pneumoperitoneum on the vectorcardiogram　obtained with the Frank lead system kn-title=気腹によるベクトル心電図の変化 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Vectorcardiograms were recorded with the Frank lead system during laparoscopy. Pneumoperitoneum produced the following significant vectorcardiographic changes: (1) The maximum spatial QRS vector increased in magnitude and shifted horizontally and slightly anteriorly. (2) The L/W ratio of the frontal QRS loop decreased. (3) The scalar data of each X, Y, Z lead of the QRS loop increased. In particular, the increases in R of all three leads and in S of lead Z were significant. These results suggest that the changes in the cardiac anatomic position due to lift of the diaphragma and a decrease of left ventricular end-diastolic volume might produce these vectorcardiographic changes during laparoscopy. en-copyright= kn-copyright= en-aut-name=TerasakaRitsuko en-aut-sei=Terasaka en-aut-mei=Ritsuko kn-aut-name=寺坂律子 kn-aut-sei=寺坂 kn-aut-mei=律子 aut-affil-num=1 ORCID= en-aut-name=YamanariHiroshi en-aut-sei=Yamanari en-aut-mei=Hiroshi kn-aut-name=山成洋 kn-aut-sei=山成 kn-aut-mei=洋 aut-affil-num=2 ORCID= en-aut-name=TogawaJunichiro en-aut-sei=Togawa en-aut-mei=Junichiro kn-aut-name=戸川潤一郎 kn-aut-sei=戸川 kn-aut-mei=潤一郎 aut-affil-num=3 ORCID= en-aut-name=IharaKeiko en-aut-sei=Ihara en-aut-mei=Keiko kn-aut-name=井原敬子 kn-aut-sei=井原 kn-aut-mei=敬子 aut-affil-num=4 ORCID= en-aut-name=KobikiNaoki en-aut-sei=Kobiki en-aut-mei=Naoki kn-aut-name=小曳直樹 kn-aut-sei=小曳 kn-aut-mei=直樹 aut-affil-num=5 ORCID= en-aut-name=HagiharaHidenori en-aut-sei=Hagihara en-aut-mei=Hidenori kn-aut-name=萩原英紀 kn-aut-sei=萩原 kn-aut-mei=英紀 aut-affil-num=6 ORCID= en-aut-name=MatsunoShigeru en-aut-sei=Matsuno en-aut-mei=Shigeru kn-aut-name=松野繁 kn-aut-sei=松野 kn-aut-mei=繁 aut-affil-num=7 ORCID= en-aut-name=MatsubaraKatashi en-aut-sei=Matsubara en-aut-mei=Katashi kn-aut-name=松原堅 kn-aut-sei=松原 kn-aut-mei=堅 aut-affil-num=8 ORCID= en-aut-name=YamadaNobuyuki en-aut-sei=Yamada en-aut-mei=Nobuyuki kn-aut-name=山田信行 kn-aut-sei=山田 kn-aut-mei=信行 aut-affil-num=9 ORCID= en-aut-name=YoshidaHidenori en-aut-sei=Yoshida en-aut-mei=Hidenori kn-aut-name=吉田英紀 kn-aut-sei=吉田 kn-aut-mei=英紀 aut-affil-num=10 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大冶 kn-aut-sei=斎藤 kn-aut-mei=大冶 aut-affil-num=11 ORCID= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=12 ORCID= en-aut-name=TsujiTakao en-aut-sei=Tsuji en-aut-mei=Takao kn-aut-name=辻孝夫 kn-aut-sei=辻 kn-aut-mei=孝夫 aut-affil-num=13 ORCID= affil-num=1 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=2 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=3 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=4 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=5 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=6 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=7 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=8 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=9 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=10 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=11 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=12 en-affil= kn-affil=岡山大学第一内科学教室 affil-num=13 en-affil= kn-affil=岡山大学第一内科学教室 en-keyword=腹腔鏡検査 kn-keyword=腹腔鏡検査 en-keyword=vectorcardiogram kn-keyword=vectorcardiogram en-keyword=pneumoperitoneum kn-keyword=pneumoperitoneum END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=1 article-no= start-page=17 end-page=22 dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=19970910 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of human infection with Diphyllobothrium in Fukuyama City, Hiroshima Prefecture kn-title=福山市の1男性から駆出された裂頭条虫について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Three strobilae with scoleces were expelled from a 16-year-old man by the administration of 600mg (20mg/kg) praziquantel. The No.1 strobila had a scolex 6.5cm in length. The No.2 strobila had a scolex 28cm in length. The No.3 strobila with a scolex and mature segments was 142cm in length. The No.3 strobila was identified as Diphyllobothrium latum by its morphological characteristics. The No.1 strobila had a scolex similar to that of the No.3 strobila. However, the No.2 strobila was equipped with a hammer-like scolex. This result suggests that the No.2 strobila belonged to species other than D. Latum. en-copyright= kn-copyright= en-aut-name=KazunoHiroshi en-aut-sei=Kazuno en-aut-mei=Hiroshi kn-aut-name=数野博 kn-aut-sei=数野 kn-aut-mei=博 aut-affil-num=1 ORCID= en-aut-name=ChoTohru en-aut-sei=Cho en-aut-mei=Tohru kn-aut-name=長亨 kn-aut-sei=長 kn-aut-mei=亨 aut-affil-num=2 ORCID= en-aut-name=KobayashiTakako en-aut-sei=Kobayashi en-aut-mei=Takako kn-aut-name=小林孝子 kn-aut-sei=小林 kn-aut-mei=孝子 aut-affil-num=3 ORCID= en-aut-name=KusauraJunko en-aut-sei=Kusaura en-aut-mei=Junko kn-aut-name=草浦潤子 kn-aut-sei=草浦 kn-aut-mei=潤子 aut-affil-num=4 ORCID= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=5 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=ちょう外科医院 affil-num=2 en-affil= kn-affil=ちょう外科医院 affil-num=3 en-affil= kn-affil=福山市医師会総合検診センター affil-num=4 en-affil= kn-affil=福山市医師会総合検診センター affil-num=5 en-affil= kn-affil=斎藤獣医科病院 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部 en-keyword=裂頭条虫 (Diphyllobothrium) kn-keyword=裂頭条虫 (Diphyllobothrium) en-keyword=人体症例 (human case) kn-keyword=人体症例 (human case) en-keyword=広島県 (Hiroshima Prefecture) kn-keyword=広島県 (Hiroshima Prefecture) END start-ver=1.4 cd-journal=joma no-vol=8 cd-vols= no-issue=2 article-no= start-page=165 end-page=168 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Plerocercoids of Nybelinia surmenicola vomited from a domestic cat in Fukuyama City, Japan kn-title=ネコから吐出されたNybelinia surmenicolaの擬充尾虫 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Two infective larval forms of Tetrarynchoidea-cestode were vomited from a domestic cat in 1995. The worms were identified with the plerocercoid of Nybelinia surmenicola by their morphological features, especially the shape and numbers of hooks on the proboscis. This is the first case of Nybelinia-plerocercoid infection in a domestic cat in Japan. en-copyright= kn-copyright= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=1 ORCID= en-aut-name=HabaraToshiyuki en-aut-sei=Habara en-aut-mei=Toshiyuki kn-aut-name=羽原利幸 kn-aut-sei=羽原 kn-aut-mei=利幸 aut-affil-num=2 ORCID= en-aut-name=YamaguchiHiroyuki en-aut-sei=Yamaguchi en-aut-mei=Hiroyuki kn-aut-name=山口裕之 kn-aut-sei=山口 kn-aut-mei=裕之 aut-affil-num=3 ORCID= en-aut-name=YoshidaKunie en-aut-sei=Yoshida en-aut-mei=Kunie kn-aut-name=吉田邦恵 kn-aut-sei=吉田 kn-aut-mei=邦恵 aut-affil-num=4 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=斎藤獣医科病院 affil-num=2 en-affil= kn-affil=公立学校共済組合中国中央病院臨床検査科 affil-num=3 en-affil= kn-affil=山口動物病院 affil-num=4 en-affil= kn-affil=吉田動物クリニック affil-num=5 en-affil= kn-affil=岡山大学医療技術短期大学部 en-keyword=四吻条虫 kn-keyword=四吻条虫 en-keyword=ニベリニア (Nybelinia surmenicola) kn-keyword=ニベリニア (Nybelinia surmenicola) en-keyword=擬充尾虫 kn-keyword=擬充尾虫 en-keyword=プレロセルコイド (plerocercoid) kn-keyword=プレロセルコイド (plerocercoid) en-keyword=猫 (cat) kn-keyword=猫 (cat) en-keyword=Hiroshima Prefecture kn-keyword=Hiroshima Prefecture END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue=1 article-no= start-page=15 end-page=18 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20011225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Detection of metacercariae of Spelotrema capellae in crabs from Sanyo District, Japan kn-title=山陽地方のカニにおける吸虫Spelotrema capellaeのメタセルカリアの感染状況 en-subtitle= kn-subtitle= en-abstract=The detection of metacercariae of Spelotrema capellae was investigated in crabs that inhabited the river mouth in the Sanyo District, Japan. The metacercaria was detected in crabs from 4 areas of the Hiroshima Prefecture and from 1 area of the Okayama Prefecture. From 2 areas in the Hiroshima Prefecture, the crab, Hemigrapsus penicillatus, showed the high prevalence of metacercariae. This crab could be a source of infection by Spelotrema capellae in domestic cats in these areas. kn-abstract=吸虫Spelotrema capellaeの飼い猫への感染源を調べるために,広島県福山市を中心とした瀬戸内沿岸の河口域に生息するカニにおけるメタセルカリアの感染状況を調査した｡調査地のうち広島児内の4ヵ所と岡山県内の1ヵ所のケフサイソガニHemigrapsus PenicillatusからS. capellaeのメタセルカリアが検出された｡特に,過去に症例報告のあった猫の行動圏内にある福山市の2ヵ所のケフサイソガニからは高率に検出された｡したがってこれらの地方においては飼い猫へのS. capellaeの感染源は河口産のケフサイソガニであることが強く示唆された｡ en-copyright= kn-copyright= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=1 ORCID= en-aut-name=KuyaMitsuo en-aut-sei=Kuya en-aut-mei=Mitsuo kn-aut-name=久家光雄 kn-aut-sei=久家 kn-aut-mei=光雄 aut-affil-num=2 ORCID= en-aut-name=HashiguchiMasahiro en-aut-sei=Hashiguchi en-aut-mei=Masahiro kn-aut-name=橋口正大 kn-aut-sei=橋口 kn-aut-mei=正大 aut-affil-num=3 ORCID= en-aut-name=IkedaFumio en-aut-sei=Ikeda en-aut-mei=Fumio kn-aut-name=池田文雄 kn-aut-sei=池田 kn-aut-mei=文雄 aut-affil-num=4 ORCID= en-aut-name=YamaguchiHiroyuki en-aut-sei=Yamaguchi en-aut-mei=Hiroyuki kn-aut-name=山口裕之 kn-aut-sei=山口 kn-aut-mei=裕之 aut-affil-num=5 ORCID= en-aut-name=YoshidaKunie en-aut-sei=Yoshida en-aut-mei=Kunie kn-aut-name=吉田邦恵 kn-aut-sei=吉田 kn-aut-mei=邦恵 aut-affil-num=6 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=斎藤獣医科病院 affil-num=2 en-affil= kn-affil=広島県立教育センター affil-num=3 en-affil= kn-affil=福山市市民病院 affil-num=4 en-affil= kn-affil=池田獣医科 affil-num=5 en-affil= kn-affil=山口動物病院 affil-num=6 en-affil= kn-affil=吉田動物クリニック affil-num=7 en-affil= kn-affil=岡山大学法学部 en-keyword=Spelotrema capellae kn-keyword=Spelotrema capellae en-keyword=ケフサイソガニ (crab) kn-keyword=ケフサイソガニ (crab) en-keyword=Hemigrapsus penicillatus kn-keyword=Hemigrapsus penicillatus en-keyword=メタセルカリア (metacercaria) kn-keyword=メタセルカリア (metacercaria) en-keyword=山陽地方 (Sanyo District) kn-keyword=山陽地方 (Sanyo District) END start-ver=1.4 cd-journal=joma no-vol=12 cd-vols= no-issue=2 article-no= start-page=119 end-page=122 dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020320 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case report of Homalogaster paloniae from the cecum of a bull in Fukuyama City kn-title=牛の盲腸に寄生した平腹双口吸虫Homalogaster paloniaeの1症例 en-subtitle= kn-subtitle= en-abstract=Twenty-two worms were taken out from the cecum of a bull at the slaughterhouse in Fukuyama City. These worms were identified as adult Homalogaster paloniae by its morphological features. However, we were unable to determine the infection route of these worms. It was suggested that the bull was infected with Homalogaster paloniae in the birthplace, Okayama Prefecture. kn-abstract=広島県福山市のとちく場で1頭の牛の盲腸より22匹の吸虫を検出し､形態的特徴より総て平腹双口吸虫Homalogaster paloniaeの成虫と同定した｡この牛は岡山県真庭郡川上村で生まれ､そこで約10ヶ月飼育されていた｡福山市の牧場内には､この吸虫の中間宿主であるヒラマキモドキガイが生息するような環境はなく､岡山県で飼育されていた時にこの吸虫に感染した可能性が高いと推察された｡ en-copyright= kn-copyright= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=1 ORCID= en-aut-name=IgamiNorio en-aut-sei=Igami en-aut-mei=Norio kn-aut-name=居神憲男 kn-aut-sei=居神 kn-aut-mei=憲男 aut-affil-num=2 ORCID= en-aut-name=TaguchiKazufumi en-aut-sei=Taguchi en-aut-mei=Kazufumi kn-aut-name=田口和史 kn-aut-sei=田口 kn-aut-mei=和史 aut-affil-num=3 ORCID= en-aut-name=ShigetoKaduhiro en-aut-sei=Shigeto en-aut-mei=Kaduhiro kn-aut-name=重東和宏 kn-aut-sei=重東 kn-aut-mei=和宏 aut-affil-num=4 ORCID= en-aut-name=TakaokiMie en-aut-sei=Takaoki en-aut-mei=Mie kn-aut-name=高沖美江 kn-aut-sei=高沖 kn-aut-mei=美江 aut-affil-num=5 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=斎藤獣医科病院 affil-num=2 en-affil= kn-affil=福山市食肉衛生検査所 affil-num=3 en-affil= kn-affil=福山市食肉衛生検査所 affil-num=4 en-affil= kn-affil=福山市食肉衛生検査所 affil-num=5 en-affil= kn-affil=福山市食肉衛生検査所 affil-num=6 en-affil= kn-affil=岡山大学法学部 en-keyword=平腹双口吸虫 (Homalogaster paloniae) kn-keyword=平腹双口吸虫 (Homalogaster paloniae) en-keyword=牛 (bull) kn-keyword=牛 (bull) en-keyword=盲腸 (cecum) kn-keyword=盲腸 (cecum) en-keyword=福山市 (Fukuyama City) kn-keyword=福山市 (Fukuyama City) END start-ver=1.4 cd-journal=joma no-vol=13 cd-vols= no-issue=2 article-no= start-page=67 end-page=75 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=20030320 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Examination of informed consent to preoperative esophagus cancer patient kn-title=食道がん患者に対する術前インフォームド･コンセントの検討 en-subtitle= kn-subtitle= en-abstract=It is important for the patients with esophageal cancer to receive truth telling about their illness as well as to have informed consent fully concerning treatment method when making self-decision. There have been few reports about the self-decision oriented informed consent which were analyzed with qualitative induction research. We therefore conducted qualitative research using semi-structured questionnaire to elucidate how an informed consent should be conducted to support the patients to make self-decision for accepting surgical treatment. As results, 1. Informed consent should not be an event but a process according to capacity of the patients for understanding their own illness. 2. Explanation about the condition following an operation, especially about the symptom or the procedure causing pain, should be supportive for the patients with picturing a specific image, considering the personality of the patients. 3. Supportive system for patients after receiving informed consent and making a decision accepting surgical treatment should be improved because of insufficient sharing of information among medical team members. kn-abstract=食道がん患者が食道切除術を受けることを自己決定する場合には,食道癌であることの告知と､食道癌に対する治療方法に関するインフォームド･コンセントが重要となる｡食道がん患者の治療法選択における自己決定を指向したインフォームド･コンセントの有り様について,質的帰納的に分析した文献は少ない｡今回,食道がん患者に対して,半構成的質問用紙を用いて,面接を実施することで,患者が治療法として手術を自己決定するために役立つインフォームド･コンセントとはどのようにあればいいかを明らかにした｡その結果,患者が食道切除術を受けることを決めるためには,@患者の理解度にあわせ,何度かに分けてインフォームド･コンセントが行われる必要があること,A術後に起こってくる症状,特に患者にとって苦痛を伴う検査,処置等については,患者のパーソナリティーを考えながら,術後のイメージがわくような説明が必要であること,B患者の自己決定に至る過程のみならず,インフォームド･コンセント後においても,患者や家族を支援する体制が重要であること,が明らかになった｡ en-copyright= kn-copyright= en-aut-name=MoriKeiko en-aut-sei=Mori en-aut-mei=Keiko kn-aut-name=森恵子 kn-aut-sei=森 kn-aut-mei=恵子 aut-affil-num=1 ORCID= en-aut-name=KanaoNaomi en-aut-sei=Kanao en-aut-mei=Naomi kn-aut-name=金尾直美 kn-aut-sei=金尾 kn-aut-mei=直美 aut-affil-num=2 ORCID= en-aut-name=NanbaKayo en-aut-sei=Nanba en-aut-mei=Kayo kn-aut-name=難波佳代 kn-aut-sei=難波 kn-aut-mei=佳代 aut-affil-num=3 ORCID= en-aut-name=IshikawaTakako en-aut-sei=Ishikawa en-aut-mei=Takako kn-aut-name=石川貴子 kn-aut-sei=石川 kn-aut-mei=貴子 aut-affil-num=4 ORCID= en-aut-name=SaitoShinya en-aut-sei=Saito en-aut-mei=Shinya kn-aut-name=斎藤信也 kn-aut-sei=斎藤 kn-aut-mei=信也 aut-affil-num=5 ORCID= en-aut-name=NaomotoYoshio en-aut-sei=Naomoto en-aut-mei=Yoshio kn-aut-name=猶本良夫 kn-aut-sei=猶本 kn-aut-mei=良夫 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部保健学科看護学専攻 affil-num=2 en-affil= kn-affil=国立病院四国がんセンター affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院西病棟3階 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院西病棟3階 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院消化器･腫瘍外科 affil-num=6 en-affil= kn-affil=岡山大学医歯学総合研究科消化器･腫瘍外科 en-keyword=インフォームド･コンセント (Informed consent) kn-keyword=インフォームド･コンセント (Informed consent) en-keyword=食道がん (esophagus cancer) kn-keyword=食道がん (esophagus cancer) en-keyword=治療法の選択 (selecting treatment method) kn-keyword=治療法の選択 (selecting treatment method) en-keyword=自己決定 (self-determination) kn-keyword=自己決定 (self-determination) END start-ver=1.4 cd-journal=joma no-vol=67 cd-vols= no-issue= article-no= start-page=92 end-page=98 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=199611 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=気管支喘息に対する複合温泉療法の作用機序 2.内分泌･自律神経系および心因的要素に対する効果 kn-title=Action mechanisms of complex spa therapy on bronchial asthma. 2. Effects on endocrine-autonomic nerve system and psychological factors en-subtitle= kn-subtitle= en-abstract=内分泌･自律神経系および心因的要素に対する温泉療法の効果が,気管支喘息を対象に検討された｡内分泌系では,血中コーチゾ-ルおよびACTH値が,温泉療法後に上昇することが示された｡また,自律神経系では,血中アドレナリンおよびノルアドレナリン濃度が温泉療法により減少することが示され,特に,血中アドレナリンは温泉療法前後の濃度に有意の差が見られた｡しかしながら,血中サブスタンスPおよびブラジキニン濃度には,温泉療法による有意の変動は見られなかった｡心因的要素に対する温泉療法の作用を検討するため,CMI,SDS,CAIおよびSDの4種類の心身医学的検査が行われた｡その結果,いずれの心身医学的検査においても,温泉療法により疾患に不利に働く心因的要素が改善する傾向が見られた｡これらの結果より,温泉療法が内分泌･自律神経系に対して有用な作用を有し,また,疾患に不利な心因的要素を改善させる作用を有していることがある程度示唆された｡ kn-abstract=Actions of spa therapy on endocrine-autonomic nerve system and psychological factors were analyzed in patients with bronchial asthma. In endocrine function, serum levels of cortisol and ACTH tended to increase after spa therapy. In autonomic nerve system, decrease in concentrations of serum adrenalin and noradrenalin was observed after spa therapy, and the difference between the initial levels before spa therapy and the levels after the therapy was significant in serum levels of adrenalin. However, serum levels of substance P and Bradykinin were not affected by spa therapy. To evaluate the action of spa therapy on mental condition in patients with asthma, four kinds of psychological tests, CMI, SDS, CAl and SD, were carried out. Improvement of mental disorders in patients with asthma is observed after spa therapy in all psychological tests. These results suggest that spa therapy acts effectively on endocrine-autonomic nerve system and improve psychological conditions. en-copyright= kn-copyright= en-aut-name=MifuneTakashi en-aut-sei=Mifune en-aut-mei=Takashi kn-aut-name=御舩尚志 kn-aut-sei=御舩 kn-aut-mei=尚志 aut-affil-num=1 ORCID= en-aut-name=MitsunobuFumihiro en-aut-sei=Mitsunobu en-aut-mei=Fumihiro kn-aut-name=光延文裕 kn-aut-sei=光延 kn-aut-mei=文裕 aut-affil-num=2 ORCID= en-aut-name=HosakiYasuhiro en-aut-sei=Hosaki en-aut-mei=Yasuhiro kn-aut-name=保崎泰弘 kn-aut-sei=保崎 kn-aut-mei=泰弘 aut-affil-num=3 ORCID= en-aut-name=AshidaKozo en-aut-sei=Ashida en-aut-mei=Kozo kn-aut-name=芦田耕三 kn-aut-sei=芦田 kn-aut-mei=耕三 aut-affil-num=4 ORCID= en-aut-name=YokotaSatoshi en-aut-sei=Yokota en-aut-mei=Satoshi kn-aut-name=横田聡 kn-aut-sei=横田 kn-aut-mei=聡 aut-affil-num=5 ORCID= en-aut-name=TsugenoHirofumi en-aut-sei=Tsugeno en-aut-mei=Hirofumi kn-aut-name=柘野浩史 kn-aut-sei=柘野 kn-aut-mei=浩史 aut-affil-num=6 ORCID= en-aut-name=TakeuchiKazuaki en-aut-sei=Takeuchi en-aut-mei=Kazuaki kn-aut-name=竹内一昭 kn-aut-sei=竹内 kn-aut-mei=一昭 aut-affil-num=7 ORCID= en-aut-name=NawaYuichiro en-aut-sei=Nawa en-aut-mei=Yuichiro kn-aut-name=名和由一郎 kn-aut-sei=名和 kn-aut-mei=由一郎 aut-affil-num=8 ORCID= en-aut-name=TanizakiYoshiro en-aut-sei=Tanizaki en-aut-mei=Yoshiro kn-aut-name=谷崎勝朗 kn-aut-sei=谷崎 kn-aut-mei=勝朗 aut-affil-num=9 ORCID= en-aut-name=SaitoKatsuyoshi en-aut-sei=Saito en-aut-mei=Katsuyoshi kn-aut-name=斎藤勝剛 kn-aut-sei=斎藤 kn-aut-mei=勝剛 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=6 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=9 en-affil= kn-affil=岡山大学医学部附属病院三朝分院内科 affil-num=10 en-affil= kn-affil=土肥病院内科 en-keyword=Bronchial asthma (気管支喘息) kn-keyword=Bronchial asthma (気管支喘息) en-keyword=Spa therapy (温泉療法) kn-keyword=Spa therapy (温泉療法) en-keyword=Endocrine-autonomic nerve system (内分泌・自律神経系) kn-keyword=Endocrine-autonomic nerve system (内分泌・自律神経系) en-keyword=Psychological disorders (心的要素) kn-keyword=Psychological disorders (心的要素) END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=1-2 article-no= start-page=189 end-page=197 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=199002 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical investigation of cerebral infarction accompanined by atrial fibrillation kn-title=心房細動合併脳梗塞症例の臨床的検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A retrospective study of 166 cases of cerebral infarction who were treated at the Takamatsu Red Cross Hospital from 1983 to 1986 was conducted. 1) There was no significant relationship between cases of cerebral infarction deaths and smoking, alcohol consumption, high blood cholesterol levels, high blood neutral fal levels or diabetes. 2) Those cases of cerebral infarction which were complicated by heat disease or atrial fibrillation demonstrated a significantly higher mortality rate. 3) From among a total of 20 cases of cerebral infarction complicated with heart disease, 12 cases had a simultaneous complication of atrial fibrillation. The most common type of heart disease observed was cardiac valve disease, which was present im 7 of the cases. 4) All 4 cases of cardiac infarction were not complicated by atrial fibrillation. 5) All of the cases of death due to cerebral infarction compicated by heart disease were also complicated by atrial fibrillation. These finding indicate the importance of atrial fibrillation in cases of cerebral inflarction. A study of the clinical picture of cases of cerebral infarction complicated with atrial fibmillation was conducted. 1) The clinical picture od cases of cerebral infarction complicated by atrial fibrillation frequently involed cerebral embolism and the site of infarction was frequently observed to be the dendrifrom cerebral cortex. In addition, these cases were usually quite severe, even resulting in consiousness disorders and also involved a high mortality rate. 2) In comparison to cases which were not complicated by atrial fibrillation, there was no significant difference observed between such cases nd survivors of cerebral infarction complicated by atrial fibrillaiton in terms of their function of movement and social life style. Based on the above, atrial fibrillation is believed to be a major risk factor of cerebral infarction irrespective of the presence or absence of underlying disorders. en-copyright= kn-copyright= en-aut-name=TaijiSogo en-aut-sei=Taiji en-aut-mei=Sogo kn-aut-name=十河泰司 kn-aut-sei=十河 kn-aut-mei=泰司 aut-affil-num=1 ORCID= en-aut-name=KumuraMasashi en-aut-sei=Kumura en-aut-mei=Masashi kn-aut-name=木村正司 kn-aut-sei=木村 kn-aut-mei=正司 aut-affil-num=2 ORCID= en-aut-name=KobikiNaoki en-aut-sei=Kobiki en-aut-mei=Naoki kn-aut-name=小曳直樹 kn-aut-sei=小曳 kn-aut-mei=直樹 aut-affil-num=3 ORCID= en-aut-name=OgasawaraNozomi en-aut-sei=Ogasawara en-aut-mei=Nozomi kn-aut-name=小笠原望 kn-aut-sei=小笠原 kn-aut-mei=望 aut-affil-num=4 ORCID= en-aut-name=HaraokaShoichi en-aut-sei=Haraoka en-aut-mei=Shoichi kn-aut-name=原岡昭一 kn-aut-sei=原岡 kn-aut-mei=昭一 aut-affil-num=5 ORCID= en-aut-name=SaitoDaiji en-aut-sei=Saito en-aut-mei=Daiji kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=6 ORCID= en-aut-name=TsujiTakao en-aut-sei=Tsuji en-aut-mei=Takao kn-aut-name=辻孝夫 kn-aut-sei=辻 kn-aut-mei=孝夫 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=高松赤十字病院循環器科 affil-num=2 en-affil= kn-affil=高松赤十字病院循環器科 affil-num=3 en-affil= kn-affil=高松赤十字病院循環器科 affil-num=4 en-affil= kn-affil=高松赤十字病院内科 affil-num=5 en-affil= kn-affil=岡山大学医学部中央検査部 affil-num=6 en-affil= kn-affil=岡山大学医学部中央検査部 affil-num=7 en-affil= kn-affil=岡山大学医学部第一内科学教室 en-keyword=脳梗塞 kn-keyword=脳梗塞 en-keyword=心房細動 kn-keyword=心房細動 en-keyword=脳塞栓 kn-keyword=脳塞栓 en-keyword=皮質枝型梗塞 kn-keyword=皮質枝型梗塞 END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=4 article-no= start-page=445 end-page=454 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Usefulness of body surface maps for discriminating old myocardial infarction in cases with ECG findings of poor R wave progression kn-title=Poor R Wave Progression 例における陳旧性前壁梗塞の鑑別―体表面心臓電位図による検討― en-subtitle= kn-subtitle= en-abstract= kn-abstract=The clinical usefulness of the body surface maps (maps) to discriminate old anterior myocardial infarction (OAMI) in patients whose ECG showed poor R wave progression (PRWP) was examined. The maps of 60 patients with PRWP, including 33 cases of OAMI and 27 without myocardial infarction (non-MI) were recorded. The multivariate stepwise discriminant analysis elucidated that 5 leads (G4, C3, J5, B3, A5) of the QRST area map would contribute to the discrimination of OAMI from non-MI, and the the formula z=-6.0×G4+26.8×C3+9.1×J5-14.0×B3-9.0×A5-1.1(unit : 0.1mVS), using these parameters two groups were separated with a sensitivity of 90.9% and a specificity of 96.3%. The discriminating performance using 5 leads (G4, H2, H4, L6, M5)of the QRS area map and 5 leads (G5, G2, H4, L5, M5) of the Q20 map gave a sensitivity of 90.9%, and 93.9%, and specificity of 96.3%, and 92.6%, respectively. Furthermore, for formula was applied to 26 new consecutive patients with PRWP for evaluating this formula. The indicies obrained from the QRST area map gave the best results, and provided a sensitivity of 85.7% and a specificity of 100%. In the pattern of the QRST area map, the existence of the regions less than-20μVS can fairly identify the OAMI (sensitivity 87.9%, specificity 85.2%). These findings suggest that the mathematical models obtained from the result of map analysis, especially QRST area maps, are useful to discriminate OAMI among the cases with PRWP. en-copyright= kn-copyright= en-aut-name=IharaKeiko en-aut-sei=Ihara en-aut-mei=Keiko kn-aut-name=井原敬子 kn-aut-sei=井原 kn-aut-mei=敬子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一内科学教室 en-keyword=old myocardial infraction kn-keyword=old myocardial infraction en-keyword=body surface mapping kn-keyword=body surface mapping en-keyword=poor R wave progression kn-keyword=poor R wave progression END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=11-12 article-no= start-page=1193 end-page=1205 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical significance of body surface mapping for a diagnosis of left ventricular hypertrophy : Special reference to a differential diagnosis between hypertrophic cardiomyopathy and hypertension-induced left ventricular hypertrophy kn-title=体表面電位図による心肥大の病態の推定と鑑別診断―特に肥大型心筋症と高血圧性肥大心の鑑別診断を中心に― en-subtitle= kn-subtitle= en-abstract= kn-abstract=The present study was conducted to clarify electrophysiological characteristics of left ventricular hypertrophy (LVH) and to discriminate hypertrophic cardiomyopathy (HCM) from hypertension-induced LVH with body surface mapping. QRS area map, QRST area map and VAT map of body surface mapping were recorded on 37 patients with HCM, 37 with essential hypertension (EH) and 21 with aortic regurgitation (AR) using Yamada's method. HCM, EH and AR showed similar patterns of QRS area map. However, the maximum points of QRST area map located at the midsternal line (E5) in HCM, and positioned on the left midclavicular line (G4) in EH and AR. The minimum point of the QRST area map appeared at the left midclavicular line (G3) where the maximum point of the QRS area map was located. These findings indicate that the QRST area map would enable to differentiate HCM from EH and AR. With the VAT map, AR showed closed isochrone lines on the left precordium, which indicated delayed ventricular activation in this region. Statistical analysis revealed that the value of the maximum point of the QRST area (Max. QRST) and the sum of values of the positive QRST area ( positive QRST area) differentiates HCM from EH. When the Max. QRST was 0.6μVs or less and the positive QRST area was 14μVs or less, the diagnostic accuracy of HCM could be made more than 70%. These findings suggested that the diagnostic criteria derived from the QRST area map is of use to distinguish HCM from hypertension-induced LVH. en-copyright= kn-copyright= en-aut-name=MatsubaraKatashi en-aut-sei=Matsubara en-aut-mei=Katashi kn-aut-name=松原堅 kn-aut-sei=松原 kn-aut-mei=堅 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部循環器内科学教室 en-keyword=Hypertrophic cardiomyopaty kn-keyword=Hypertrophic cardiomyopaty en-keyword=Hypertensive left ventricular hypertrophy kn-keyword=Hypertensive left ventricular hypertrophy en-keyword=Body surface mapping kn-keyword=Body surface mapping END start-ver=1.4 cd-journal=joma no-vol=102 cd-vols= no-issue=1-2 article-no= start-page=63 end-page=76 dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=199002 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Changes of extravascular lung water after hepatic ischemia by Pringle's maneuver Part 1. In regard to the increase of the extravascular lunh water and its cause kn-title=Pringle 法急性肝流入血行遮断の肺血管外水分量におよぼす影響　第1編　肺血管外水分量の増加とその成因を中心として en-subtitle= kn-subtitle= en-abstract= kn-abstract=To elucidate the effect of total hepatic ischemia on pulmonary organs, extravascular lung water (EVLW) was experimentally measured using a modified double indicator dilution method before and after interruption of the hepatic blood flow using Pringle's maneuver. The follow-ing results were obtained : 1) EVLW was significantlly increased more than one hour after temporary total hepatic ischemia. 2) Temporary hypotension resulted in little increase of EVLW by removing and replacing some blood volume through the femoral artery. 3) Pumonary interstitial edema was histologically and maroscopically observed in the Pringle's maneuver group. 4) Marked metabolic acidosis and elevation of serum transaminase were revealed after temporary hepatic ischemia. These findings auggest that pulmonary interstitial edema may result from sfter temporary total hepatic ischemia by Pringle's maneuver and the changes of EVLW are caused by increased permeability due to liver injury, metabolic acidosis and portal congestion. en-copyright= kn-copyright= en-aut-name=YokoyamaNobuji en-aut-sei=Yokoyama en-aut-mei=Nobuji kn-aut-name=横山伸二 kn-aut-sei=横山 kn-aut-mei=伸二 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=Pringle 法急性肝流入血行遮断 kn-keyword=Pringle 法急性肝流入血行遮断 en-keyword=肺血管外水分量 kn-keyword=肺血管外水分量 END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=11-12 article-no= start-page=1183 end-page=1191 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Radiographic studies on lumbar spines of steel plant workers in relation to the pathogenesis of low back pain kn-title=製鉄所従業員における腰椎のX線学的研究―腰痛の発生とX線所見との関連について― en-subtitle= kn-subtitle= en-abstract= kn-abstract=In recent years, incidence of low back pain (LBP) has been increasing. To clarify the relation between instability of the lumbar spine and LBP in heavy industry workers, radiographic findings were compared with a questionnaire on 2863 workers in a steel plant, as a preliminary study in 1986. In 214 males, 4-direction X-ray examinations of the lumbar vertebrae were obtained and the results were analyzed along with a questionnaire survey. The examined subjects were classified into three groups according to their complaints into : A ; LBP free, B ; LBP moderate, and C ; LBP severe. Degeneration chages of the facet joint, lumbar disc narrowing, angles between vertebrae, and lumbar lordosis were investigated on the X-ray film. In general, the higher the intensity of LBP, the more intervertebral angles at all levels of the lumbar spine and the more severe the degeneration. There was a statistically significant difference between the A and C group in the intervertebral angles at lower levels. Incidence of the lumbar disc narrowing differed between the two groups. The instabilitiy of lumbar spine was found in the C group. Low back pain in the heavy industry workers can be caused by anterior motion factors such as lumbar disc narrowing rather than posterior motion factors such as degeneration of the facet joint. en-copyright= kn-copyright= en-aut-name=IwagawaMotoyuki en-aut-sei=Iwagawa en-aut-mei=Motoyuki kn-aut-name=岩河基行 kn-aut-sei=岩河 kn-aut-mei=基行 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部整形外科学教室 en-keyword=Low back pain kn-keyword=Low back pain en-keyword=Radiographic study kn-keyword=Radiographic study en-keyword=Instability kn-keyword=Instability en-keyword=Facet joint kn-keyword=Facet joint en-keyword=Lumbar disc narrowing kn-keyword=Lumbar disc narrowing END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=5-6 article-no= start-page=639 end-page=649 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Long-term follow-up study od total hip replacement in rheumatoid arthritis kn-title=慢性関節リウマチにおける全人工股関節置換術長期成績に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A long-term follow up study was performed on 125 total hip replacements (THR) in 95 rheumatoid patients. The average follow up time was 8 years and 5 months, ranging from 5 to 17 years. Except in 26 cases of death or 9 incomplete histories at the follow-up, 62 cases were investigated both clinically and radiologically. For the operations, two types of prostheses (Charnley and C-Muller ) were used. According to the Japan Orthopaedic Association (JOA) hip score, the preoperative score improved from 32.9 to 57.1 points at the final postoperative evaluation. In the radiological assessment using the method by Nagaya and Uno, a clear zone was seen around the acetabular cup in 82.2% of the hips and around the femoral stem in 53.2%. Rate of loosening corresponding to stage V and W was 20.2% in the acetabular side and 32.9% in the femoral side. Charnley-type group was better than C-Muller type both in clinical and radiological assessments. Twelve cases had lost walking ability. As postoperative complications, deep infections occurred in 4 hips, femoral shaft fracture in 4 hips, dislocation in 1 hip and revision due to aseptic loosening in 4 hips. THR may be useful for rheumatoid patients and improve the quality of life in the case of long-term disease if careful pre-and post-operative care is provided. en-copyright= kn-copyright= en-aut-name=OosakiKazuhiko en-aut-sei=Oosaki en-aut-mei=Kazuhiko kn-aut-name=大ｱ和彦 kn-aut-sei=大ｱ kn-aut-mei=和彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部整形外科学教室 en-keyword=慢性関節リウマチ kn-keyword=慢性関節リウマチ en-keyword=全人工股関節置換術 kn-keyword=全人工股関節置換術 en-keyword=長期追跡調査 kn-keyword=長期追跡調査 en-keyword=合併症 kn-keyword=合併症 END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=4 article-no= start-page=247 end-page=255 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Oncogene mRNA in gastric cancer by in situ hybridization by using a biotin-labeled probe kn-title=Biotin 標識 probe を用いた histo in situ hydridization 法による胃癌組織における癌遺伝子 mRNA の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Expression of oncogene mRNA in gastric cancer was studied by in situ hybridization. Cancer tissues were fixed in formalin and embeded in paraffin. Then, DNA-mRNA hybridization was performed by using two biotin-labeled cDNA probes (c-myc, c-Ha ras). Oncogene mRNA was intracuelularly localized, mainly in the cytoplasm, and also found in the nucleus of partial cells. Higher concentrations of oncogene mRNA vere found in advanced cancers than in early cancers, and in metastatic positive cases of the above n2 than of n0 or n1. This suggests that the expression of oncogene mRNA is related to the malignant potency of cancer. en-copyright= kn-copyright= en-aut-name=TanakaIzuru en-aut-sei=Tanaka en-aut-mei=Izuru kn-aut-name=田中出 kn-aut-sei=田中 kn-aut-mei=出 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=histo in situ hybridization 法 kn-keyword=histo in situ hybridization 法 en-keyword=胃癌 kn-keyword=胃癌 en-keyword=癌遺伝子 kn-keyword=癌遺伝子 en-keyword=ｍRNA kn-keyword=ｍRNA END start-ver=1.4 cd-journal=joma no-vol=103 cd-vols= no-issue=1-2 article-no= start-page=183 end-page=197 dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=1991 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental study on pathogenesis and treatment of cerebral vasospasm Part 2. Effects of PGI2 analogue, thromboxane A2 synthetase inhibitor and Ca blocker on experimental delayed spasm models kn-title=脳血管攣縮の発生機序と治療に関する実験的研究 第2編 実験的遅発性脳血管攣縮に対する PGI2 analogue, Thromboxane A2 合成酵素阻害剤, Ca 拮抗剤の効果 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The effects of a PGI2 analogue (OP-41483), a thromboxane A2 synthetase inhibitor (OKY-046) and a Ca blocker (nifedipine) on the diameter of constricted basilar arteries and on the regional cerebral blood flow (r-CBF) in the brain stem were investigated in the cat delayed spasm model. The experiment was performed three days (72 hours) after artificial subarachnoid hemorrhage. The basilar artery was exposed transclivally, and more advanced vasospasm was produced by topical application of a lysed erythrocyte solution for 5 to 6 hours which domonstrated no more vascular dilatation even by topical application of papaverine hydrochloride (0.01mg/ml). In the delayed spasm model, the intravenous administration of neither OP-41483 (8μg/kg), OKY-046 (60mg/kg) nor nifedipine (0.003mg/kg) affected the vascular diameter. OP-41483 increased r-CBF in the brain stem in 3, and nifedipine increased it in 4 out of the 5 studied delayed spasm models, whereas OKY-046 never increased r-CBF (n=5). There was no significant difference in the amount of fatty acids including arachidonic acid between normal and constricted arteries. This study suggested that thromboxane A2 is not the major factor of cerebral vasospasm and OKY-046 might not be effective on vascular diameter or r-CBF at the late spasm stage. However, the PGI2 analogue (OP-41483) and Ca blocker (nifedipine) may be effective in increasing r-CBF even at the late spasm stage. en-copyright= kn-copyright= en-aut-name=MotokiMototsugu en-aut-sei=Motoki en-aut-mei=Mototsugu kn-aut-name=元木基嗣 kn-aut-sei=元木 kn-aut-mei=基嗣 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部脳神経外科教室 en-keyword=cerebral vasospasm kn-keyword=cerebral vasospasm en-keyword=thromboxane A2 kn-keyword=thromboxane A2 en-keyword=OP-41483 kn-keyword=OP-41483 en-keyword=OKY-046 kn-keyword=OKY-046 en-keyword=nifedipine kn-keyword=nifedipine END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=5-6 article-no= start-page=445 end-page=455 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on pathogenesis of intractable asthma Part 2. Clinical features of late onset intractable asthma kn-title=難治性喘息の発症病態に関する研究　第2編　中高年発症型難治性喘息の臨床像について en-subtitle= kn-subtitle= en-abstract= kn-abstract=To clarify the pathogenesis of late onset intractable asthma (LOIA), 102 asthmatics were classified into early (<40y.o.) and late onset asthma (>40y.o.), or intractable and non-in-tractable asthma. Clinical and allergic examinations were evaluated in each asthma group. Sixty nine percent of the late onset asthmatics had perennial type attacks. IgG-as well as IgE-mediated allergic reactions were suggested by the findings of immediate skin reaction, IgE RIST and RAST score to Candida allergen and reactivity of basophils to anti-immunoglobulin antisera in LOIA. Neutrophils in bronchoalveolar lavage fluid increased significantly in LOIA as compared with the early onset intractable asthma (EOIA) groups (p<0.05). In the pulmonary function test, a striking fall of % V25 was observed in both EOIA ans LOIA. The chest X-ray film frequently revealed microndular shadows in LOIA. Marked morphological changes in the transbronchial lung biopsied specimens were observed in the late onset asthmatics. These findings suggest that a non-IgE reaction, neutrophil infiltration in the local allergic site and histolpgical changes of lung tissue lead to LOIA. en-copyright= kn-copyright= en-aut-name=NakayamaKengo en-aut-sei=Nakayama en-aut-mei=Kengo kn-aut-name=中山堅吾 kn-aut-sei=中山 kn-aut-mei=堅吾 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=late onset kn-keyword=late onset en-keyword=intractable asthma kn-keyword=intractable asthma en-keyword=IgG kn-keyword=IgG en-keyword=neutrophil kn-keyword=neutrophil en-keyword=transbronchoscopic lung biopsy kn-keyword=transbronchoscopic lung biopsy END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=5-6 article-no= start-page=433 end-page=443 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on pathogenesis of intractable asthma Part 1. Characteristices of clinical and immuno-pathological findings in intractable asthma kn-title=難治性喘息の発症病態に関する研究　第1編　難治性喘息の臨床的検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=To clarify the pathogenesis of intractable asthma, clinical features, allergic examinations, pulmonary functions and histological finding were evaluated in 27 intractable asthmatics compared with 33 non-intractable asthmatics. Almost all of the intractable asthmatics had chronic and perennial asthma attacks and also had highly frequent episodes of respiratory infection. IgG-as well as IgE-mediated allergic reactions were proved by the findings of skin reaction, IgE RAST score, precipitating antibody and reactivity of basophils to anti-immunoglobulin antisera in the intractable asthmatics but not in the non-intactable asthmatics. Neutrophils of BALF and peripheral blood increased markedly in the intractable asthmatics as compared with the non-intractable asthmatics. The fall of % V(25) on flow volume curve in the intractable asthmatics, indicated small air way obstruction. Micronodular shadows on the chest X-ray film were frequently seen in the intractable asthmatics. Many histological findings were shown on lung specimens obtained by TBLB in the intrac-table asthmatics. These findings indicate that multiple factors of allergic reaction mediated by IgG, migrated neutrophils and organic changes of lung tissue lead to severe and intractable asthma attack. en-copyright= kn-copyright= en-aut-name=NakayamaKengo en-aut-sei=Nakayama en-aut-mei=Kengo kn-aut-name=中山堅吾 kn-aut-sei=中山 kn-aut-mei=堅吾 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=intractable asthma kn-keyword=intractable asthma en-keyword=Candida kn-keyword=Candida en-keyword=IgG kn-keyword=IgG en-keyword=neutrophil kn-keyword=neutrophil en-keyword=transbronchoscopic lung biopsy kn-keyword=transbronchoscopic lung biopsy END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=11-12 article-no= start-page=1007 end-page=1014 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199212 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on immunoprophylactic effects of OK-432 and Ge-132 on methylcholanthrene-induced mouse sarcoma Part 1. Suppressive effects of OK-432 and Ge-132 with respect to timing of administration, and the role of natural killer cells kn-title=BRM（OK-432 および Ge-132）によるメチルコラントレン誘発肉腫の発症抑制に関する研究 第1編 OK-432 および Ge-132 の投与時期による肉腫の発症に対する抑制効果および natural killer（NK)細胞の関与 en-subtitle= kn-subtitle= en-abstract= kn-abstract=C3H mice were subcutaneously (s.c.) injected with a tumorigenic dose (1mg/mouse) of 3-methylcholanthrene (MC) and tumor development was observed for 18 weeks. OK-432 or Ge-132 was intraperitoneally administered either after MC injection (post-treatment) or both before and after MC injection (pre- and post-treatment). Pre- and post-treatment with OK-432 significantly inhibited the development of tumors from 10 to 12 weeks after MC injection as compared with a control group. In all of the groups, the incidence of tumors was 100 percent 18 weeks after MC injection. With respect to Ge-132, both post-treatment and pre- and post-treatment administration reduced tumor growth in a similar manner to pre- and post-treatment of OK-432. After pre-treatment with OK-432 or Ge-132 for two weeks, the percentage of large granular lymphocytes in peripheral blood and the natural killer activity of splenic cells in mice were increased. These results suggest that the immune status plays an important role in the defense mechanisms against chemically-induced tumors. en-copyright= kn-copyright= en-aut-name=TamaiMamoru en-aut-sei=Tamai en-aut-mei=Mamoru kn-aut-name=玉井守 kn-aut-sei=玉井 kn-aut-mei=守 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=Methylcholanthrene-induced sarcoma kn-keyword=Methylcholanthrene-induced sarcoma en-keyword=OK-432 kn-keyword=OK-432 en-keyword=Ge-132 kn-keyword=Ge-132 en-keyword=NK cell kn-keyword=NK cell END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=1-2 article-no= start-page=107 end-page=115 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=1992 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Anticoagulant effect of nafamostat mesilate (FUT) and cepharanthin on the small-caliber prosthesis implantation in the small venous system kn-title=メシル酸ナファモスタットとセファランチンの併用による小口径静脈再建後早期における抗血栓作用に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The anticoagulant effect of nafamostat mesilate(FUT, a protease inhibitor) plus cepharanthin (CE) after small-caliber graft implantation into the canine jugular veins was compared with that of heparin (HE) or urokinase (UK). Twenty-four dogs were used in this study. Sauvage EXS Dacron grafts 5mm in diameter were implanted into external jugular veins. Immediately after impantation, continuous administration of drugs was started through posterior auricular veines. Coagulation test were carried out serially during perfusion. Three hours after implantation, the grafts were removed and examined macro-and microscopically. The dogs were divided into 4 groups : 1)Control group ; 2)UK group (2000u/kg/hr) ; 3)HE group (0.25mg/kg/hr) ; and 4)FUT plus CE group, FUT (0.3mg/kg/hr) plus CE (0.7mg/kg/hr). All grafts were thrombosed in the control group and UK group. However, no thrombus was found in the HE group anf FUT plus CE group. Coagulation tests revealed that fibrinogen and AT-V decreased significantly in the UK group (p<0.05), ACT and APTT was gradually prolonged in the HE group (p<0.05), and there was no significant change in the FUT plus CE group. These findings suggest that FUT plus CE may not only decrease early thrombus formation, but may also maintain the balance of the coagulation system. The combination of FUT plus CE may be useful anticoagulant therapy during the postoperative period when the risk of bleeding remains. en-copyright= kn-copyright= en-aut-name=OkanoKazuo en-aut-sei=Okano en-aut-mei=Kazuo kn-aut-name=岡野和雄 kn-aut-sei=岡野 kn-aut-mei=和雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=抗血栓作用 kn-keyword=抗血栓作用 en-keyword=メシル酸ナファモスタット kn-keyword=メシル酸ナファモスタット en-keyword=セファランチン kn-keyword=セファランチン en-keyword=小口径人工血管 kn-keyword=小口径人工血管 en-keyword=静脈再建 kn-keyword=静脈再建 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=9-10 article-no= start-page=885 end-page=895 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199210 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effect of nutritional intake on energy metabolism in postoperative patients after gastrointestinal surgery kn-title=間接熱量測定による消化器手術後のエネルギー代謝の検討―投与量･投与経路の比較― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Many studies have shown that enteral nutrition (EN) has nutritional effects comparable to total parenteral nutrition (TPN). However, the energy metabolism of the two different nutritioanl methods remains undefined. The two nutritional methods were compared by measuring the resting energy expenditure (REE) and nutritional assessment in postoperative patients after gastrointestinal surgery. The effects of different amounts of EN were also evaluated. Patients were diveded into three groups : Patients who were fed by EN of 30 Cal/kg/day (Group I, EN 30 : n=8), patients who were fed by EN of 40 Cal/kg/day (Group II, EN 40 : n=8), and patients who were fed by TPN of 30 Cal/kg/day (Group III, TPN : n=8). REE was measured by the Datex indirect calorimetry and nutritional assessment included the measurements of triceps skinfold thickness (TSF), arm muscle circumference (AMC), albumin and rapid turnover proteins. ％REE/BEE of EN30, EN40 and TPN was 122.5±14.3%, 138.2±16.8% and 107.6±10.5% respectively. The RQ for the three groups was about 1.0, which means the energy source of all regimens is carbohydrate. The TPN group showed a significantly higher RQ than the EN groups, but there was no difference in albumin or transferrin. There was no difference in nutritional effect between EN 30 and EN 40. No difference was found in anthropometric effects among the three groups. These findings suggest that 30 Cal/kg/day would be preferable to 40 Cal/kg/day in energy supply of enteral nutrition and that the energy expenditure of EN is higher than that of TPN under 30 Cal/kg/day nutrition. There is no difference among the three mehtods in terms of nutritional effects. en-copyright= kn-copyright= en-aut-name=YoshizaneKen en-aut-sei=Yoshizane en-aut-mei=Ken kn-aut-name=吉實憲 kn-aut-sei=吉實 kn-aut-mei=憲 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=間接熱量計 kn-keyword=間接熱量計 en-keyword=経腸栄養 kn-keyword=経腸栄養 en-keyword=経静脈栄養 kn-keyword=経静脈栄養 en-keyword=代謝熱量 kn-keyword=代謝熱量 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=7-8 article-no= start-page=809 end-page=820 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on IgG subclass antibodies in asthmatics with late asthmatic responses Part 2. Antigen-specific IgG subclass antibodies in the BALF of asthmatics with late asthmatic responses kn-title=遅発型気道反応におけるIgG サブクラス抗体に関する研究　第2編　気管支肺胞洗浄液中抗原特異的 IgG サブクラス抗体と遅発型気道反応の関連について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Immunoglobulin classes which induce a non-immediate asthmatic response (non-IAR) in the case of low level of IgE antibody are still unknown, although IAR is mediated by IgE. To elucidate the relationship between antibodies and late asthmatic responses (LAR), antigen-specific IgG subclass antibodies in the serum and bronchoalveolar lavage fluid (BALF) of asthmatics were measured by avidin-biotin ELISA before provocation by antigen. The BALF levels of IgG and IgG1 antibodies to mite and Candida antigen in bronchial asthmatics were higher than those in healthy subjects (p<0.05). Followed by inhalation of house dust or Candida antigen, bronchial asthmatics were divided into group A (higher levels of BALF IgG1 antibody) and gourp B (lower levels of BALF IgG1 antibody). The percentages of LAR including DAR after inhalation of house dust antigen in group A were significantly higher than those in group B (p<0.05). The percentages of LAR including DAR after inhalation of Candida antigen in group A were significantly higher than those in group B (p<0.01). In asthmatics with LAR after inhalation of house dust antigen or Candida antigen, the BALF levels of antigen-specific IgG and IgG1 antibodies were significantly higher than those in asthmatics without LAR of healthy subjects (p<0.01). In asthmatics with LAR after inhalation of house dust antigen or Candida antigen, the BALF levels of antigen-specific IgG and IgG1 antibodies were significantly higher than those in asthmatics without LAR of healthy subjects (p<0.01). In asthmatics with LAR, the relative (to albumin) of coefficients of excretion (RCE) in the BALF of antigen-specific IgG and IgG1 antibodies were higher than those in asthmatics without LAR of healthy subjects. These findings suggest that local production of antigen-specific IgG and IgG1 antibodies incerases in asthmatics with LAR, and that these antibodies may induce LAR. en-copyright= kn-copyright= en-aut-name=OgurusuKazuro en-aut-sei=Ogurusu en-aut-mei=Kazuro kn-aut-name=小栗栖和郎 kn-aut-sei=小栗栖 kn-aut-mei=和郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=遅発型気道反応 kn-keyword=遅発型気道反応 en-keyword=IgG サブクラス抗体 kn-keyword=IgG サブクラス抗体 en-keyword=気管支肺胞洗浄 kn-keyword=気管支肺胞洗浄 en-keyword=難治性喘息 kn-keyword=難治性喘息 en-keyword=抗原吸入誘発試験 kn-keyword=抗原吸入誘発試験 END start-ver=1.4 cd-journal=joma no-vol=104 cd-vols= no-issue=7-8 article-no= start-page=789 end-page=795 dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=199208 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The relationships between physique and throwing ability in high school baseball players kn-title=高校野球選手における形態と投能力の関係 en-subtitle= kn-subtitle= en-abstract= kn-abstract=There is little information on anthropometric measures (i. e., length, breadth and girth of body's parts) related to throwing ability. To clarify the influence of the physique on the throwing ability, the relationships between physique and throwing distance, as well as ball speed were investigated. The subjects were fourty-nine high school baseball players, and thirty-eight high school volleyball players, football players and canoeists served as a control group. The throwing distance was significantly related to lean body mass (r=.290), chest girth (r=.416), upper arm girth (r=.307), abdominal girth (r=.288), thigh girth (r=.327) and lower leg girth (r=.285) in baseball players group (p<0.05-0.01). A significant relationship between the throwing distance and foot length in control group (r=.329, p<0.05) was demonstrated. Significant relationships between ball speed and standing height in the baseball players group (r=.354, p<0.01) and that between ball speed and Impedance in the control group (r=-.288, p<0.05) were ovserved. These findings indicate that the throwing distance is influenced by quantity of body muscle in baseball players. There was no relation between physique and throwing ability in unskilled players. en-copyright= kn-copyright= en-aut-name=UchidaHayato en-aut-sei=Uchida en-aut-mei=Hayato kn-aut-name=内田勇人 kn-aut-sei=内田 kn-aut-mei=勇人 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学教室 en-keyword=野球選手 kn-keyword=野球選手 en-keyword=形態 kn-keyword=形態 en-keyword=遠投距離 kn-keyword=遠投距離 en-keyword=ボールスピード kn-keyword=ボールスピード en-keyword=Impedance kn-keyword=Impedance END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=5-6 article-no= start-page=619 end-page=628 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=1993 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Stusies on the pathogenesis in diffuse panbronchiolitis Part 2. Immune responses in diffuse panbronchiolitis kn-title=びまん性汎細気管支炎の病態に関する研究　第2編　びまん性汎細気管支炎患者の免疫能 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Various immunological processes are suspected of having some relationship with the onset of diffuse panbronchiolitis (DPB). Therefore, the cellular and humoral immunity of patients with DPB were studied. Sera of patients with DPB showed a high frequency of positive RA factor and high titer of cold agglutinin. Delayed skin tests with phytohemagglutinin (PHA) and purified protein derivative (PPD) in patients with DPB revealed normal responses to PHA as nonspecific mitogen and suppressed responses to PPD as specific antigen, although lymphocyte blastogenesis in vitro showed suppressed responses to PHA. The proportion of lymphocytes in bronchoalveolar lavage (BAL) fluid of DPB patients equaled that of normal controls. Furthermore, the CD4/CD8 ratio of T-cell subsets in BAL fluid of DPB patients were significantly lower than that of normal controls, although the CD4/CD8 ratio in peripheral blood of DPB were significantly higher than that in normal controls. The percentage of B-cells in the peripheral blood of DPB patients was hihger than that in normal controls. These data suggest that the activation of cellular and humoral immune mechanisms could play an important role in the pathogenesis of DPB. en-copyright= kn-copyright= en-aut-name=ShiraishiTakamasa en-aut-sei=Shiraishi en-aut-mei=Takamasa kn-aut-name=白石高昌 kn-aut-sei=白石 kn-aut-mei=高昌 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=びまん性汎細気管支炎 kn-keyword=びまん性汎細気管支炎 en-keyword=気管支肺胞洗浄 kn-keyword=気管支肺胞洗浄 en-keyword=リンパ球サブセット kn-keyword=リンパ球サブセット en-keyword=皮内反応 kn-keyword=皮内反応 en-keyword=リンパ球幼若化反応 kn-keyword=リンパ球幼若化反応 END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=5-6 article-no= start-page=513 end-page=526 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=1993 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical investigation of ventricular direct interaction in valvular heart diseases before and after surgery by means of the equilibrium radionuclide ventriculography kn-title=後天性弁膜疾患の手術前後における左室と右室の直接的相互作用に関する研究― RI 心プール法を用いて― en-subtitle= kn-subtitle= en-abstract= kn-abstract=To elucidate direct ventricular interaction, equilibrium radionuclide ventriculography was performed on 18 cases of aortic regurgitation (AR) and 31 cases of mitral stenosis(MS) before and after open heart surgery. Patients with AR were divided into two groups by preoperative left ventricular volume : the normovolumic left ventricle (n-LV) group and the dilated left ventricle (d-LV) group. Patients with MS were divided into two groups by preoperative right ventricular volume : the normovolumic right ventricle (n-RV) group and the dilated rihgt ventricle (d-RV) group. In patients with AR, preoperative right ventricular systolic function in the d-LV group was significantly impaired compared with that in the n-LV group. Postoperative right ventricular systolic function in the d-LV group improved to show no significant difference compared to that in the n-LV group because surgery alleviated the left ventricular dilatation. In patients with MS, preoperative left ventricular systolic and diastolic functions in the d-RV group were significantly impaired compared with that of n-RV group. In d-RV group, postoperative left ventricular systolic and diastolic functions were significantly improved wheh right ventricular dilatation could be relieved postoperatively. In the present study, the existence of direct ventricular interaction influenced by the volume-overloaded ventricle was clarified. en-copyright= kn-copyright= en-aut-name=ArakiKazuhiro en-aut-sei=Araki en-aut-mei=Kazuhiro kn-aut-name=荒木一博 kn-aut-sei=荒木 kn-aut-mei=一博 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=後天性弁膜疾患 kn-keyword=後天性弁膜疾患 en-keyword=RI 心プール法 kn-keyword=RI 心プール法 en-keyword=左室機能 kn-keyword=左室機能 en-keyword=右室機能 kn-keyword=右室機能 en-keyword=心室間直接的相互作用 kn-keyword=心室間直接的相互作用 END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=5-6 article-no= start-page=489 end-page=498 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=1993 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical trial of enhancement method fro ultrasonographic diagnosis of thyroid nodules kn-title=結節性甲状腺腫の超音波診断における Enhancement 法の試み en-subtitle= kn-subtitle= en-abstract= kn-abstract=Enhancement in thyroid ultrasonography was investigated with thyroid lymphography by injection of Lipiodol into thyroid nodules in 50 patients. On plain thyroid ultrasonography (PU), the echo levels of normal and tumorous portions of the thyroid glands were evaluated. Then, the echo level ratios (P-N/T) were calculated. Moreover, by the same method, the echo level ratios between normal and tumorous portions of the thyroid glands were culculated 6 hours after Lipiodol injection (E-N/T), when the greatest enhancement was anticipated. The mean value of P-N/T was 1.305, and that of E-N/T was 1.474. The echo level ratio was significantly elevated in the enhancement method (p<0.0014). We concluded that the enhancement is obtained with Lipiodol injection into the normal portion of the thyroid glands, regardless of whether the tumor is benign or malignant and with or without cystic degeneration. This method is useful in promoting quality and location diagnosis of thyroid nodules. N : echo level value in the normal portion of thyroid gland T : echo level value in the tumorous portion of thyroid gland N/T : echo level raito en-copyright= kn-copyright= en-aut-name=TakeuchiRyuzo en-aut-sei=Takeuchi en-aut-mei=Ryuzo kn-aut-name=竹内龍三 kn-aut-sei=竹内 kn-aut-mei=龍三 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=超音波診断 kn-keyword=超音波診断 en-keyword=結節性甲状腺腫 kn-keyword=結節性甲状腺腫 en-keyword=Enhancement kn-keyword=Enhancement en-keyword=甲状腺リンパ造影 kn-keyword=甲状腺リンパ造影 en-keyword=エコーレベル kn-keyword=エコーレベル END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=11-12 article-no= start-page=945 end-page=955 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19931231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on respiratory disorders induced by drug allergy Part 1. Clinical features and mechanism of drug allergy kn-title=薬剤誘起性アレルギー性呼吸器疾患の発症病態に関する研究　第1編　病像とアレルギー学的検査成績による臨床的検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=To clarify the pathogenesis of respiratory disease induced by drug allergy, clinical features and allergic examinations were evaluated in 9 patients (10 episodes). The ten episodes were classified as a case with bronchospasm, 7 cases with PIE (pulmonary infiltration with eosinophilia) syndrome and 2 cases with IP (interstitial pneumonia) according to clinical features and chest X-ray findings. In the case of bronchospasm, serum IgE level was low and Prausnitz-Kustner reaction was negative. However, increased LTC4 and LTD4 production in peripheral leukocytes and a normal level of histamine release in whole blood induced by the causative drug were shown. All cases of PIE syndrome revealed positive DLST (drug lymphocyte stimulation test). Four of 7 cases with PIE syndrome had high levels of serum IgE. One case showed decreased serum IgE level as the pulmonary infiltrtation shadow improved. In cases of IP, positive DLST and increased lymphocytes in BAL (bronchoalveolar lavage) fluid were shown. Four cases of PIE syndrome and a case of IP underwent BAL revealing an increase of eosinophils in all cases and an increase of lymphocytes of 3/5 cases. DLST using BAL lymphocyte revealed a higher stimulation index compared to that using peripheral lymphocyte. These results suggest that non-IgE-mediated allergic reaction in bronchospasm, IgE-mediated allergic reaction in PIE syndrome, and cell-mediated allergic reaction in PIE syndrome and IP are involved in pulmonary changes induced by drug allergy. en-copyright= kn-copyright= en-aut-name=MifuneTakashi en-aut-sei=Mifune en-aut-mei=Takashi kn-aut-name=御舩尚志 kn-aut-sei=御舩 kn-aut-mei=尚志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=薬剤性呼吸器疾患 kn-keyword=薬剤性呼吸器疾患 en-keyword=喘息発作 kn-keyword=喘息発作 en-keyword=PIE kn-keyword=PIE en-keyword=間質性肺炎 kn-keyword=間質性肺炎 en-keyword=DLST kn-keyword=DLST END start-ver=1.4 cd-journal=joma no-vol=105 cd-vols= no-issue=1-2 article-no= start-page=227 end-page=229 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Measurement of cyclosporine concentration using radioimmunoassay with a specific monoclonal antibody : Preparing for the liver transplantation program in Okayama University Medical School kn-title=シクロスポリン特異的モノクロナル抗体を用いたラジオイムノアッセイ法によるシクロスポリン血中濃度測定法について―岡山大学肝移植プログラム準備の一環として― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Cyclosporine, a new strong immunosuppressive agent, has dramatically improved the outcome of liver transplantation since its introduction to the clinical field in the 1980s. Despite its efficacy, cyclosporine has a very narrow therapeutic window, wthich requires fine adjustment of the appropriate dose based on its concentration in the blood. It will be necessary to obtain reliable data on a daily basis, when the liver transplantation program actually starts in the near future. To address this problem, we examined the utility of the radioimmunoassay kit using a specific monoclonal antibody (CYCLO-Trac WHOLE-BLOOD, Baxter, Japan), compared with the data derived from a commercial laboratory service (SRL, Japan). Each value of the cyclosporine concentration in the whole blood, measurely by CYCLO-Trac correlated with that of SRL(p<0.0001). CYCLO-Trac was suggested to be useful in obtaining a reliable data on a daily basis within our hospital. en-copyright= kn-copyright= en-aut-name=SaitoShinya en-aut-sei=Saito en-aut-mei=Shinya kn-aut-name=斎藤信也 kn-aut-sei=斎藤 kn-aut-mei=信也 aut-affil-num=1 ORCID= en-aut-name=SakagamiKenichi en-aut-sei=Sakagami en-aut-mei=Kenichi kn-aut-name=阪上賢一 kn-aut-sei=阪上 kn-aut-mei=賢一 aut-affil-num=2 ORCID= en-aut-name=MatsunoTsuyoshi en-aut-sei=Matsuno en-aut-mei=Tsuyoshi kn-aut-name=松野剛 kn-aut-sei=松野 kn-aut-mei=剛 aut-affil-num=3 ORCID= en-aut-name=OritaKunzo en-aut-sei=Orita en-aut-mei=Kunzo kn-aut-name=折田薫三 kn-aut-sei=折田 kn-aut-mei=薫三 aut-affil-num=4 ORCID= en-aut-name=AkiyamaTakao en-aut-sei=Akiyama en-aut-mei=Takao kn-aut-name=龝山隆夫 kn-aut-sei=龝山 kn-aut-mei=隆夫 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部第一外科学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部附属病院核医学診療室 en-keyword=シクロスポリン kn-keyword=シクロスポリン en-keyword=モノクロナル抗体 kn-keyword=モノクロナル抗体 en-keyword=ラジオイムノアッセイ法 kn-keyword=ラジオイムノアッセイ法 en-keyword=腎移植 kn-keyword=腎移植 en-keyword=肝移植 kn-keyword=肝移植 END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=11-12 article-no= start-page=1143 end-page=1157 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199412 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the pathogenesis of diffuse panbronchiolitis (DPB) in regard of the effects of erythromycin therapy kn-title=びまん性汎細気管支炎の病態に関する研究―エリスロマイシンの作用機序を中心に― en-subtitle= kn-subtitle= en-abstract= kn-abstract=DPB has been known as a chronic respiratory infection with poor prognosis until introduction of erythromycin (EM) therapy with low-dose and long-term administration. As symptoms and prognosis of DPB were improved enormously under EM therapy, EM therapy on DPB was analyzed to clarify the action and mechanisms. EM in a daily dese of 600 mg was administered to 9 patients with DPB for about 38 months and 7 normal volunteers for 2 months. Most patients with DPB showed the relief of symptoms within 2 months, although the EM concentrations in the blood and sputa were lower than the antibacterial therapeutic level. Immunological examination revealed the decrease in cold agglutinin titer and CD4/CD8 ratio after EM therapy. The neutrophil chemotactic factor (NCF) derived from the mononuclear cell culture of DPB patients was higher than that in the normal control. EM therapy decreased the level of NCF not only in patients with DPB but also in normal volunteers. These findings indicate that the immunological effects of EM play an important role in the treatment of DPB. en-copyright= kn-copyright= en-aut-name=IrieShoichiro en-aut-sei=Irie en-aut-mei=Shoichiro kn-aut-name=入江正一郎 kn-aut-sei=入江 kn-aut-mei=正一郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=diffuse panbronchiolitis kn-keyword=diffuse panbronchiolitis en-keyword=erythromycin kn-keyword=erythromycin en-keyword=リンパ球 kn-keyword=リンパ球 en-keyword=neutrophil chemotatic factor kn-keyword=neutrophil chemotatic factor END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=7-8 article-no= start-page=789 end-page=798 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199408 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Human T-lymphotropic virus type-Tinfection and pulmonary fibrosing changes in patients with lung cancer kn-title=肺癌患者における HTLV-T感染と間質性肺病変に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Thirty-one patients with lung cancer in Okinawa known as HTLV-Tendemic area, and 140 patients in Okayama were evaluated in regard to HTLV-Tinfection and iterstitial pulmonary shadows. The presence of HTLV-Tinfection was examined by the polymerase chain reaction (PCR) method in peripheral blood mononuclear cells, and indirect immunofluorescent (IF) assay in sera. Interstitial pulmonary shadows on the chest roentgenograph, were classified according to the grade of fibrosis. The rate of HTLV-Tinfection in patients with lung cancer was higher than that in healthy controls by IF assay in both districts. The rate of anti-HTLV-Tantibody was higher in lung cancer patients with severe fibrosis than in those with milder fibrosis, but the grade of fibrosis and existence of pX gene had no relation in Okinawa or in Okayama. The incidence of patients with anti-HTLV-Tantibody was higher in patients with adenocarcinoma and squamous cell carcinoma than in those with small cell carcinoma. These findings suggested that HTLV-Tinfection was closely involved in some patients with non-small cell lung cancer having intersitital pulmonary shadows. en-copyright= kn-copyright= en-aut-name=NanbaSeiji en-aut-sei=Nanba en-aut-mei=Seiji kn-aut-name=難波靖治 kn-aut-sei=難波 kn-aut-mei=靖治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=肺癌 kn-keyword=肺癌 en-keyword=びまん性間質性肺病変 kn-keyword=びまん性間質性肺病変 en-keyword=polymerase chain reaction kn-keyword=polymerase chain reaction en-keyword=間接蛍光抗体法 kn-keyword=間接蛍光抗体法 en-keyword=HTLV-T kn-keyword=HTLV-T END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=1-2 article-no= start-page=13 end-page=29 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960229 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The expansion and antitumoral activity of recombinant IL-2 activated tumor infiltrating lymphocytes from human cancers kn-title=腫瘍内浸潤リンパ球の rIL-2 添加培養と細胞傷害活性の研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Tumor infiltrating lymohocytes (TIL) were isolated from various human cancers and cultured. The expansion, cytotoxicity, phenotype, and perforin, which is considered the cytotoxic factor of killer cells, of TIL were examinel. TIL cultured in 1000u/ml recombinant interleukin-2 (rIL-2) with 20% conditioned medium (CoM) exhibited far better expansion capability than that of TIL cultured in rIL-2 1000u/ml alone, and continued to expand up to 14 weeks. The maximal expansion index (EI) was 23912. When TIL arrested expansion during the culture, the addition of PHA restored the ability to expand. The CoM was composed of spent medium from a 3-day culture of peripheral blood mononuclear cells from cancer patients. The lymphokine-activated killer (LAK) cells induced by the culture was utilized for clinical adoptive immunotherapy in our department. Cytotoxicity against K562 and Daudi target cells was highest at 2 to 3 weeks, and disappeared between 4 and 7 weeks of culture. The phenotype of fresh TIL was mainly CD3(+) T cells, predominantly CD4(+) cells, but CD8(+) cells became predominant in long term culture. The frequency of IL-2R(+) and HLA-DR+ cells was correlated with the expansiveness of TIL. The appearance and intensity of perforin positive cells were associated with the level of cytotoxicity of cultured TIL. en-copyright= kn-copyright= en-aut-name=MatsumotoMitsuaki en-aut-sei=Matsumoto en-aut-mei=Mitsuaki kn-aut-name=松本三明 kn-aut-sei=松本 kn-aut-mei=三明 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=腫瘍内浸潤リンパ球 kn-keyword=腫瘍内浸潤リンパ球 en-keyword=recombinant interleukin-2 kn-keyword=recombinant interleukin-2 en-keyword=細胞傷害活性 kn-keyword=細胞傷害活性 en-keyword=リンパ球表面抗原 kn-keyword=リンパ球表面抗原 en-keyword=パーフォリン kn-keyword=パーフォリン END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=241 end-page=252 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Hemodynamic and hormonal changes under the biventricular bypass system with ventricular fibrillated hearts kn-title=心室細動下両心バイパス型人工心臓における循環及び内分泌動態の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Hemodynamic and hormonal changes were studied in 13 sheep whose entire circulation was maintained by a biventricular bypass system with a pair of pusher-plate type blood pumps. Ventricular fibrillation was induced and pneumatically driven pumps placed outside the body kept the animals alive for 2-48 days (average: 11 days). Pump output and aortic pressure stayed within physiological ranges, but central venous pressure was elevated from 5 to 10-13 oHg after surgery. Serum levels of antidiuretic hormone, cortisol and insulin were stabilized soon after surgery. Adrenaline level and renin activity did not change significantly. For unknown reasons, the noradrenaline level showed a temporary increase after a week. Atrial natriuretic peptide (ANP) increased significantly 5 days after surgery. There were significant drops in triiodothyronine (T(3)) and thyroxine (T(4)) levels after surgery with gradual recovery afterward to 40% and 50% of the control levels, respectively. These results suggested that the biventricular bypass system maintained hemodynamic conditions similar to those maintained by the natural heart, although ANP, T(3) and T(4) values were changed. en-copyright= kn-copyright= en-aut-name=NakayamaHironobu en-aut-sei=Nakayama en-aut-mei=Hironobu kn-aut-name=中山裕宣 kn-aut-sei=中山 kn-aut-mei=裕宣 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二外科学教室 en-keyword=左右非同期 variable rate mode kn-keyword=左右非同期 variable rate mode en-keyword=両心バイパス型人工心臓 kn-keyword=両心バイパス型人工心臓 en-keyword=甲状腺ホルモン kn-keyword=甲状腺ホルモン en-keyword=心房性ナトリウム利尿ペプタイド kn-keyword=心房性ナトリウム利尿ペプタイド END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=7-8 article-no= start-page=225 end-page=240 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Spectrum analysis of arterial blood pressure waveforms kn-title=動脈圧波形の形状変化に対する周波数解析による検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is known that the shape of arterial blood pressure waveform reflects the hemodynamic status, but quantitative analyses of waveform are seldom reported. In this study, the arterial pressure wave was recorded with an intra-arterial catheter and pressure transducer, converted to digital data, and stored in a computer. The data were analyzed by two methods of spectrum analyses, i.e., fast Fourier transform (FFT for both power spectrum and phase information) and the autoregressive model (ARM). Pressure waveforms during normotension were compared with pressure waveforms during hypotension induced by vasodilators (sodium nitroprusside and nitroglycerin) in the human study, and by the vasodilators, hemorrhage or 3% isoflurane in the animal study. Reconstruction of waveforms by inverse FFT was also performed, and compared with the original waveforms. FFT is more useful than ARM for analysis of data with known frequencies, such as respiratory and heart rates. Using inverse FFT, the wave can be reconstructed by the base frequency (heart rate) to 4th harmonic data with an error margin of less than 2%. The amplitude and phase information of heart rate frequency up to its 4th harmonic, and amplitude of respiratory frequency, were found to be the essential parameters to describe the shape of the arterial pressure waveform. en-copyright= kn-copyright= en-aut-name=SaitoTomohiko en-aut-sei=Saito en-aut-mei=Tomohiko kn-aut-name=齋藤智彦 kn-aut-sei=齋藤 kn-aut-mei=智彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部麻酔・蘇生学教室 en-keyword=動脈圧波形 kn-keyword=動脈圧波形 en-keyword=周波数解析 kn-keyword=周波数解析 en-keyword=フーリエ変換 kn-keyword=フーリエ変換 en-keyword=自己回帰モデル kn-keyword=自己回帰モデル END start-ver=1.4 cd-journal=joma no-vol=106 cd-vols= no-issue=7-8 article-no= start-page=701 end-page=716 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=199408 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Endogenous colony formation in myeloproliferative disorder and myelodysplastic syndrome kn-title=骨髄増殖性疾患並びに骨髄異形成症候群におけるEndogenous CFU-C の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=An endogenous colony formation assay was performed on 24 patients with chronic myelogenous leukemia in the chronic phase (CML-CP), 11 patients with CML-accerelated phase (CML-AP), nine patients with CML-blastic crisis (CML-BC),nine patients with polycythemia vera, two patients with essential thrombocythemia, two patients with primary myelofibrosis, two patients with juvenile CML (JCML), one patient with chronic neutrophillic leukemia, two patients with unclassified myeloproliferative disorder (UMPD), five patients with refractory anemia with excess of blasts (RAEB), 10 patients with RAEB in transformation (RAEBt) or overt leukemia, and 10 patients with chronic myelomonocytic leukemia (CMML). Endogenous colony formation was observed in two patients with CML-AP, one patient with CML-BC, two patients with JCML, one patient with UMPD, one patient with RAEBt, and seven patients with CMML. All of these endogenous colonies were identified as CFU-C by chemical staining. In some patients with CML or RAEBt, endogenous colonies were observed when progression of disease occurred. Endogenous colony formation was partially inhibited by the depletion of phagocytes in five patients with CMML or RAEBt. Four of these patients revealed increased releases of granulocyte-macrophage colony stimulating factor (GM-CFS) to the culture medium, and the addition of anti-GM-CSF antibody totally inhibited the formation of endogenous colony in one case. Patients who formed endogenous colonies often had chromosomal abnormalities and short survival. These findings suggest that paracrine or autocrine GM-CSF plays an important role in endogenous colony formation and that such endogenous colony formation is one of the risk factors in hematological malignancies. en-copyright= kn-copyright= en-aut-name=MuraseToshio en-aut-sei=Murase en-aut-mei=Toshio kn-aut-name=村瀬敏夫 kn-aut-sei=村瀬 kn-aut-mei=敏夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=骨髄増殖性疾患 kn-keyword=骨髄増殖性疾患 en-keyword=骨髄異形成症候群 kn-keyword=骨髄異形成症候群 en-keyword=Endogenous CFU-C kn-keyword=Endogenous CFU-C en-keyword=慢性骨髄単球性白血病 kn-keyword=慢性骨髄単球性白血病 END start-ver=1.4 cd-journal=joma no-vol=110 cd-vols= no-issue=11-12 article-no= start-page=171 end-page=210 dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Peritoneal dissemination caused by ovarian teratoma-Especially teratomatosis peritonei-from clinicopathalogical research on 156 cases of this century kn-title=Teratomatosis Peritonei―卵巣奇形腫由来の腹膜播種性病巣に関する文献学的考察：今世紀報告された156例の臨床病理学的検討による集大成― en-subtitle= kn-subtitle= en-abstract= kn-abstract=We performed clinicopathological analyses of peritoneal dissemination caused by ovarian teratoma (PD caused by OV-T), on the English great table of 156 cases in 105 papers published in this century. We classified PD caused by OV-T into 3 categories as follows ; 1. (TP) teratomatosis peritonei (new term) : PD composed by three germ teratomas cells. 2. (GP) gliomatosis peritonei : PD composed by only glia cells. 3. (MIX) mixed type : PD composed by glia and teratoma cells. TP and MIX were newly designated in this present paper. The number of TP, GP and MIX were 22, 95 and 25, respectively. The review of these 156 cases and 105 papers were demonstrated that the clinical features between GP and TP were cleary different. TP had a more tendency of recurrentn character in comparison to GP and MIX, but had a good long survivals resulted by repeated surgical resections. en-copyright= kn-copyright= en-aut-name=KobayashiMasanao en-aut-sei=Kobayashi en-aut-mei=Masanao kn-aut-name=小林正直 kn-aut-sei=小林 kn-aut-mei=正直 aut-affil-num=1 ORCID= en-aut-name=KobayashiJun-ichi en-aut-sei=Kobayashi en-aut-mei=Jun-ichi kn-aut-name=小林淳一 kn-aut-sei=小林 kn-aut-mei=淳一 aut-affil-num=2 ORCID= en-aut-name=IwagakiHiromi en-aut-sei=Iwagaki en-aut-mei=Hiromi kn-aut-name=岩垣博巳 kn-aut-sei=岩垣 kn-aut-mei=博巳 aut-affil-num=3 ORCID= en-aut-name=TanakaNoriaki en-aut-sei=Tanaka en-aut-mei=Noriaki kn-aut-name=田中紀章 kn-aut-sei=田中 kn-aut-mei=紀章 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=小林病院　外科 affil-num=2 en-affil= kn-affil=小林病院　外科 affil-num=3 en-affil= kn-affil=岡山大学医学部外科学第一講座 affil-num=4 en-affil= kn-affil=岡山大学医学部外科学第一講座 en-keyword=ovarian teratoma kn-keyword=ovarian teratoma en-keyword=peritoneal dissemination kn-keyword=peritoneal dissemination en-keyword=teratomatosis peritonei kn-keyword=teratomatosis peritonei en-keyword=gliomatosis peritonei kn-keyword=gliomatosis peritonei END start-ver=1.4 cd-journal=joma no-vol=110 cd-vols= no-issue=7-10 article-no= start-page=107 end-page=114 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19981030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Case report of a gastric glomus tumor kn-title=胃癌を伴った胃グロームス腫瘍の1例―本邦報告例の文献的考察― en-subtitle= kn-subtitle= en-abstract= kn-abstract=The patient was a 67-year-old man who vomitted blood during therapy while hospitalized due to an asthma attack. He underwent a gastric examination, which detected a submucosal tumor on the greater curvature of the gastric antrum and gastric cancer on the lesser curvature. This tumor was diagnosed as a glomus tumor by postoperative pathological examination. In Japan, glomus tumors of stomach have been reported in 50 cases including our case. The mean age of patients was 48 years (23 to 74). Nineteen patients were male and 31 female. The main symptom was upper abdominal pain. The tumors developed in the submucosal layer of the greater curvature in the antrum and the mean size was 2.8 cm. A Angiography revealed hypervascularization and endoscopic ulutasonography showed spheroid tumors localized in the muscle layer. Proeoperative histological diagnoses were often difficult. Two cases including our patient were associated with gastric cancer. en-copyright= kn-copyright= en-aut-name=FukudaKazuma en-aut-sei=Fukuda en-aut-mei=Kazuma kn-aut-name=福田和馬 kn-aut-sei=福田 kn-aut-mei=和馬 aut-affil-num=1 ORCID= en-aut-name=AsanoHiroaki en-aut-sei=Asano en-aut-mei=Hiroaki kn-aut-name=浅野博昭 kn-aut-sei=浅野 kn-aut-mei=博昭 aut-affil-num=2 ORCID= en-aut-name=OtaniYuu en-aut-sei=Otani en-aut-mei=Yuu kn-aut-name=大谷裕 kn-aut-sei=大谷 kn-aut-mei=裕 aut-affil-num=3 ORCID= en-aut-name=MiyagutiNaoyuki en-aut-sei=Miyaguti en-aut-mei=Naoyuki kn-aut-name=宮口直之 kn-aut-sei=宮口 kn-aut-mei=直之 aut-affil-num=4 ORCID= en-aut-name=NishiHideyuki en-aut-sei=Nishi en-aut-mei=Hideyuki kn-aut-name=西英行 kn-aut-sei=西 kn-aut-mei=英行 aut-affil-num=5 ORCID= en-aut-name=ManoMasayuki en-aut-sei=Mano en-aut-mei=Masayuki kn-aut-name=間野正之 kn-aut-sei=間野 kn-aut-mei=正之 aut-affil-num=6 ORCID= en-aut-name=KomatubaraShoukiti en-aut-sei=Komatubara en-aut-mei=Shoukiti kn-aut-name=小松原正吉 kn-aut-sei=小松原 kn-aut-mei=正吉 aut-affil-num=7 ORCID= en-aut-name=KishimotoTakumi en-aut-sei=Kishimoto en-aut-mei=Takumi kn-aut-name=岸本卓巳 kn-aut-sei=岸本 kn-aut-mei=卓巳 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山労災病院外科 affil-num=2 en-affil= kn-affil=岡山労災病院外科 affil-num=3 en-affil= kn-affil=岡山労災病院外科 affil-num=4 en-affil= kn-affil=岡山労災病院外科 affil-num=5 en-affil= kn-affil=岡山労災病院外科 affil-num=6 en-affil= kn-affil=岡山労災病院外科 affil-num=7 en-affil= kn-affil=岡山労災病院外科 affil-num=8 en-affil= kn-affil=岡山労災病院内科 en-keyword=胃グロームス腫瘍 kn-keyword=胃グロームス腫瘍 en-keyword=胃癌 kn-keyword=胃癌 en-keyword=Gastric Glomus Tumor kn-keyword=Gastric Glomus Tumor END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=3-6 article-no= start-page=117 end-page=127 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960629 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Erythromycin therapy in patients with diffuse panbronchiolitis kn-title=びまん性汎細気管支炎の病態に関する研究―エリスロマイシン少量長期投与を中心に― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Low dose and long-term erythromycin (EM) therapy showed obvious improvement of symptoms and prognosis in patients with DPB. However, mechanisms involved in these clinical effects of EM therapy remain controversial. In this study, the clinical effects of EM therapy on respiratory function, bacterial flora in the lower airway and serum levels of soluble IL-2 receptor (sIL-2R) as an indicator of T-cell activation were examined. All parameters of respiratory functions in patients with DPB including % VC, % FEV 1.0, % V50, % V25 and V50/V25 showed marked improvements within 6 months of EM therapy. Continuous administration of EM for 6 to 24 months produced minimal changes in these respiratory functions though decreases in some parameters were observed in patients with advanced clinical stage and in eldely patients. The increase of % FEV 1.0 exceeded those of % V50 and % V25 after EM therapy. This indicates severe pathological changes in small airways or variable effects of EM therapy. Bacterial species and sensitivities to antibiotics showed no apparent changes after long-term EM therapy. The serum levels of sIL-2R in patients with DPB were higher than those in normal controls. With EM therapy, serum levels of sIL-2R decreased rapidly within 6 months, but these levels remained higher than those in normal controls, even after long-term EM therapy. en-copyright= kn-copyright= en-aut-name=FukudaTomoko en-aut-sei=Fukuda en-aut-mei=Tomoko kn-aut-name=福田智子 kn-aut-sei=福田 kn-aut-mei=智子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第二内科学教室 en-keyword=diffuse panbronchiolitis kn-keyword=diffuse panbronchiolitis en-keyword=erythromycin kn-keyword=erythromycin en-keyword=呼吸機能 kn-keyword=呼吸機能 en-keyword=soluble IL-2 reseptor kn-keyword=soluble IL-2 reseptor en-keyword=喀痰中細菌叢 kn-keyword=喀痰中細菌叢 END start-ver=1.4 cd-journal=joma no-vol=108 cd-vols= no-issue=3-6 article-no= start-page=83 end-page=95 dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960629 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Comparison of postoperative circulatory, respiratory and immunological parameters between one-stage and two-stage surgery of intrathoracic esophageal carcinoma kn-title=循環，呼吸，免疫動態よりみた胸部食道癌に対する1期的手術と分割手術との比較検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=There are two major surgical procedures for excision of esophageal carcinoma and reconstruction of the esophagus: the one-stage procedure and the two-stage procedure. In the present study, we evaluated the two methods by comparing the cardiovascular, respiratory and immune parameters of 10 patients who underwent one-stage procedure with those of 10 other patients who underwent two-stage procedure. To estimate cardiovascular function, we measured the left ventricular stroke work index (LVSWI)-pulmonary capillary wedge pressure (PCWP). Most of the patients treated by the one-stage procedure showed a significant decrease in LVSWI-PCWP, whereas the index of patients treated by the two-stage procedure did not change much. When we assessed the respiratory system by forced vital capacity (FVC) and peak expiratory flow (PEF), the patients treated by the two-stage procedure recovered much faster and better than those receiving the one-stage procedure. Natural killer (NK) activity in lymphocytes was also measured as a marker of the immuno-reactive system. Although most patients show a drop in NK activity one week after major surgery, NK activity did not demonstrate a significant change in any of the patients who underwent the two-stage procedume. Thus, our systemic comparison of the three different parameters demonstrated better results after the two-stage procedure and we recommend it over the one-stage procedure, especially for aged and high risk patients. en-copyright= kn-copyright= en-aut-name=MuramatsuTomoyoshi en-aut-sei=Muramatsu en-aut-mei=Tomoyoshi kn-aut-name=村松友義 kn-aut-sei=村松 kn-aut-mei=友義 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科学教室 en-keyword=intrathoracic esophageal carcinoma kn-keyword=intrathoracic esophageal carcinoma en-keyword=one-stage procedure kn-keyword=one-stage procedure en-keyword=two-stage procedure kn-keyword=two-stage procedure en-keyword=reduction of operative stress kn-keyword=reduction of operative stress END start-ver=1.4 cd-journal=joma no-vol=112 cd-vols= no-issue=3-8 article-no= start-page=89 end-page=93 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Case of Hyperestradiolemia induced by Tamoxifen kn-title=タモキシフェン投与により高エストラジオール血症を伴う両側性卵巣腫大をきたした1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A Case of hyperestradiolemia induced by Tamoxifen was reported. A 37-year old woman presented with right breast mass 3 days after delivery. The tumor, 1.2×1.0cm, was diagnosed to be cancer and quadrantectomy with axillar lymph node sampling was performed. Metastasis to the sampled lymph node (1/1) was observed. ER was negative but PgR was positive. Postoperative irradiation (50Gy) with adjuvant chemotherapy consisting of Epirubicin, CBDCA and 5FU was performed. After 2 months of Tamoxifen administration (20 mg/day), she developed vaginal bleeding and bilateral ovarian cysts with elevated serum level of estradiol (777 pg/ml). Tamoxifen for another month made the size of ovarian cysts larger and the concentration of estradiol higher (787 pg/mi). By discontinuing Tamoxifen, bilateral ovarian cysts disappeared and the level of estradiol recovered to normal in 3 months. The importance of careful observation of the hormonal environment of premenopausal breast cancer patient on Tamoxifen was discussed. en-copyright= kn-copyright= en-aut-name=MatsuokaJunji en-aut-sei=Matsuoka en-aut-mei=Junji kn-aut-name=松岡順治 kn-aut-sei=松岡 kn-aut-mei=順治 aut-affil-num=1 ORCID= en-aut-name=KojimaKazushi en-aut-sei=Kojima en-aut-mei=Kazushi kn-aut-name=小島一志 kn-aut-sei=小島 kn-aut-mei=一志 aut-affil-num=2 ORCID= en-aut-name=NoseSoichiro en-aut-sei=Nose en-aut-mei=Soichiro kn-aut-name=能勢聡一郎 kn-aut-sei=能勢 kn-aut-mei=聡一郎 aut-affil-num=3 ORCID= en-aut-name=HamayaKazuo en-aut-sei=Hamaya en-aut-mei=Kazuo kn-aut-name=浜家一雄 kn-aut-sei=浜家 kn-aut-mei=一雄 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山中央病院外科 affil-num=2 en-affil= kn-affil=岡山中央病院外科 affil-num=3 en-affil= kn-affil=岡山済生会総合病院 affil-num=4 en-affil= kn-affil=岡山済生会総合病院 en-keyword=閉経前乳癌 kn-keyword=閉経前乳癌 en-keyword=ホルモン療法 kn-keyword=ホルモン療法 en-keyword=エストラジオール kn-keyword=エストラジオール en-keyword=LH-RHアナログ kn-keyword=LH-RHアナログ END start-ver=1.4 cd-journal=joma no-vol=112 cd-vols= no-issue=3-8 article-no= start-page=75 end-page=84 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Duration of fecal shedding in enterohemorrhagic Escherichia coli O157 kn-title=腸管出血性大腸菌O157感染者における菌陰性化に要する期間についての検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In June 1997, an outbreak of enterohemorrhagic Escherichia coli O157 occurred at a hospital of Okayama City, Japan. E. coli O157 was isolated from 86 patients (40 males and 46 females). Ages ranged from 14 to 96 years old with a mean of 53 years old. All the infected patients (59 asymptomatic carriers) were investigated in this study. The median duration of shedding (from starting therapy), among the 83 patients who received antimicrobial therapy, was 6 days. This result has paticular importance for taking appropriate measures during outbreaks among adults who have other diseases. Other factors (age,sex,etc) that might have affected the duration of shedding were aiso investigated, but were not found to be influential. Among the infected patients, elderly people, females and patients who had other diseases became symptomatic, and in paticular, patients who had severe malignancy became symptomatic. All asymptomatic carriers received antimicrobial therapy and no newly affected cases and no side effects among those patients were observed. these results indicate that antimicrobial therapy for asymptomatic carriers in facilities that have a large number of susceptible people is useful. en-copyright= kn-copyright= en-aut-name=TakaoSoshi en-aut-sei=Takao en-aut-mei=Soshi kn-aut-name=高尾総司 kn-aut-sei=高尾 kn-aut-mei=総司 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学講座 en-keyword=E. coli O 157 kn-keyword=E. coli O 157 en-keyword=asymptomaic carrier kn-keyword=asymptomaic carrier en-keyword=fecal shedding time kn-keyword=fecal shedding time en-keyword=antibiotics kn-keyword=antibiotics END start-ver=1.4 cd-journal=joma no-vol=112 cd-vols= no-issue=9-12 article-no= start-page=183 end-page=189 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20001225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=An investigation into the factors of smoking cessation in male smokers kn-title=男性喫煙者の禁煙実行要因に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=This syudy was designed to clarify what factors influenced the ability to stop smoking in male smokers, from the viewpoint of life-style guidance and primary care. Of the people who attended abult health examinations between 1993 and 1998 in Okayama Ctiy, 987 male smokers were selected and categorized according to the number of cigarettes per day into three groups. The relation was analyzed statistically between the three groups and the life-style related factors : age, the degree of obesity, sleep, snacks, salt, exercise and alcohol. The results showed significant differences in age, the degree of obesity, sleep, salt, exercise. Second, the relation between threse three groups and the experience and duration of smoking cessation was analyzed. The results showed a significant differnce in the experience of smoking cessation, but no significant differnce in duration of smoking cessation. The conclusions are as follows : 1. Male smokers, who do not activedy try to improve of their life-style related factors, have fewer experiences of smoking cessation, 2. Male smokers who try to improve their life-style habits have a similar period od smoking cessation to those who do not. 3. Long term support for all male smokers to continue to be non-smoking is important. en-copyright= kn-copyright= en-aut-name=KawadaYuichi en-aut-sei=Kawada en-aut-mei=Yuichi kn-aut-name=川田諭一 kn-aut-sei=川田 kn-aut-mei=諭一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生医学講座 en-keyword=喫煙本数 kn-keyword=喫煙本数 en-keyword=生活習慣 kn-keyword=生活習慣 en-keyword=健康意識 kn-keyword=健康意識 en-keyword=健康意欲 kn-keyword=健康意欲 en-keyword=禁煙経験 kn-keyword=禁煙経験 en-keyword=再喫煙 kn-keyword=再喫煙 END start-ver=1.4 cd-journal=joma no-vol=112 cd-vols= no-issue=3-8 article-no= start-page=39 end-page=46 dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The effects of health services facilities on medical expenditure for the elderly kn-title=老人保健施設が老人医療費に与える影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=The first Health Services Facility was started in 1988, to provide the elderly with medical care services in Japan. The facilities have encouraged home care and their numbers have been increasing rapidly. In order to examine the effects of the facilities on medical expenditure for the elderly, cross-sectional and follow-up surveys were conducted with epidemiological analyses of the data from all 47 prefectures in 1990, 1993 and 1996. Multiple regression models were performed using several costs that used medical expenditure for the elderly as the explanatory variables. Furthermore, correlation coefficients between the changes in admission rates, duration of hospitalization, and the change of the numbers of beds in the facilities were calculated. The results are as follows. 1) There was a positive correlation between the cost of the facilities and medical expenditure for the elderly, but the effects have been decreasing with increased construction. 2) There was no relationship between the numbers of beds in the facilities and admission rate to the hospitals, but there was a correlation with the duration of hospitalization. en-copyright= kn-copyright= en-aut-name=OhtsuTadahiro en-aut-sei=Ohtsu en-aut-mei=Tadahiro kn-aut-name=大津忠弘 kn-aut-sei=大津 kn-aut-mei=忠弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学講座 en-keyword=老人保健施設 kn-keyword=老人保健施設 en-keyword=老人医療費 kn-keyword=老人医療費 en-keyword=入院受診率 kn-keyword=入院受診率 en-keyword=入院日数 kn-keyword=入院日数 END start-ver=1.4 cd-journal=joma no-vol=113 cd-vols= no-issue=1 article-no= start-page=87 end-page=91 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010428 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=胃 MALTリンパ腫：基礎 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=吉野正 kn-aut-sei=吉野 kn-aut-mei=正 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=赤木忠厚 kn-aut-sei=赤木 kn-aut-mei=忠厚 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学第二講座 affil-num=2 en-affil= kn-affil=岡山大学医学部病理学第二講座 END start-ver=1.4 cd-journal=joma no-vol=113 cd-vols= no-issue=1 article-no= start-page=1 end-page=16 dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010428 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Establishment of an adriamycin-resistant human bladder cancer cell line (T-24/ADM) and analysis of the mechanism of resistance kn-title=Adriamycin 耐性ヒト膀胱癌培養細胞株の樹立と耐性機序に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A human bladder cencer cell line resistant to adriamycin (ADM), T-24/ADM was establishied in vitro by exposing T-24 parent cells to a progressively higher concentration of the drug over an 18 month period. The T-24/ADM was 34.9 times more resistant to ADM than the T-24 parent. The T-24/ADM exhibited cross resistance to ADM derivatives, vinca alkaloid (vindesine, vincristine), etoposide and SN-38, but collateral sensitivity to methotrexate. The biological and biochemical characteristics of T-24/ADM were examined in terms of ADM-resistance. Although a flow cytometric analysis showed that Pglycoprotein is not expressed on the T-24/ADM cells, lower accumalation of the drug caused by decreased uptake and increaced active efflux were observed. The cellular level of glutathione-S-transferase π was 1.8-fold higher than the parent cells and the activity of nuclear extracts of DNA topoisomerase U for T-24/ADM assayed by decatenation of kinetoplast DNA was lower, about one-half that of the T-24 parent. Confocal laser microscopy revealed the difference in intracellular distribution of ADM in T-24/ADM; in particular, the accumlation of the drug in the nucleus decreased. Additionally western blot analysis showed an enhanced expression of multidrug resistance-associated protein (MRP) in the T-24/ADM cells. This resistant cell may be used as an experimantal system to elucidate the mechanisum of ADM resistance and also as a model for developing new chemotherapeutic strategies against multi-drug resistant bladder cancer. en-copyright= kn-copyright= en-aut-name=AkebiNaoki en-aut-sei=Akebi en-aut-mei=Naoki kn-aut-name=野比直樹 kn-aut-sei=野比 kn-aut-mei=直樹 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部泌尿器科学教室 en-keyword=adriamycin resistance kn-keyword=adriamycin resistance en-keyword=human bladder cancer cell line kn-keyword=human bladder cancer cell line en-keyword=multidrug resistance kn-keyword=multidrug resistance END start-ver=1.4 cd-journal=joma no-vol=115 cd-vols= no-issue=3 article-no= start-page=233 end-page=236 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=耳鼻咽喉科領域における内視鏡下鼻内手術 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=武田靖志 kn-aut-sei=武田 kn-aut-mei=靖志 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=竹内彩子 kn-aut-sei=竹内 kn-aut-mei=彩子 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=赤木成子 kn-aut-sei=赤木 kn-aut-mei=成子 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=小川晃弘 kn-aut-sei=小川 kn-aut-mei=晃弘 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山赤十字病院 耳鼻咽喉科 affil-num=2 en-affil= kn-affil=岡山赤十字病院 耳鼻咽喉科 affil-num=3 en-affil= kn-affil=岡山赤十字病院 耳鼻咽喉科 affil-num=4 en-affil= kn-affil=姫路聖マリア病院 耳鼻咽喉科 en-keyword=慢性副鼻腔炎手術の歴史 kn-keyword=慢性副鼻腔炎手術の歴史 en-keyword=鼻内法 (endonasal approach) kn-keyword=鼻内法 (endonasal approach) en-keyword=endoscopic sinus Surgery (ESS) kn-keyword=endoscopic sinus Surgery (ESS) en-keyword=osteomeatal complex (OMC) kn-keyword=osteomeatal complex (OMC) en-keyword=マイクロデブリッダー kn-keyword=マイクロデブリッダー END start-ver=1.4 cd-journal=joma no-vol=116 cd-vols= no-issue=1 article-no= start-page=9 end-page=16 dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040531 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=心不全における酸化ストレスの関与：基礎的ならびに臨床的検討 ―岡山大学医学賞（結城賞）を受賞して― en-subtitle= kn-subtitle= en-abstract= kn-abstract=心不全患者において血中の過酸化脂質の上昇などが報告され，活性酸素による酸化ストレスの関与が示唆されている．そこで，心筋が実際に活性酸素を発生するかどうかを，活性酸素を検出する蛍光プローブを用いてラットの培養心筋細胞において検討した．心不全増悪因子であるアンジオテンシンIIおよびtumor necrosis factor(TNF)-alphaを加えると心筋細胞で濃度依存性に活性酸素が発生した．さらにヒトの不全心筋においても実際に酸化ストレスの発生が増強しているかを検討した．過酸化脂質の代謝産物で，有害なアルデヒドである4-Hydroxy-2-nonenal(HNE)によって修飾された蛋白質を免疫染色にて調べたところ，拡張型心筋症患者の心筋において正常心機能者に比べ5倍以上増加していた．さらにβ遮断薬(Carvedilol)により治療を行ったところ心機能の改善とともに，HNE修飾蛋白質が40%低下した．以上の一連の研究により， 活性酸素による酸化ストレスの発生が不全心筋において増強しており，その抑制が心不全治療のターゲットの一つになりうることを明らかにした． en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=中村一文 kn-aut-sei=中村 kn-aut-mei=一文 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=草野研吾 kn-aut-sei=草野 kn-aut-mei=研吾 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=垣下幹夫 kn-aut-sei=垣下 kn-aut-mei=幹夫 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=三浦綾 kn-aut-sei=三浦 kn-aut-mei=綾 aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=久松研一 kn-aut-sei=久松 kn-aut-mei=研一 aut-affil-num=5 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=西井伸洋 kn-aut-sei=西井 kn-aut-mei=伸洋 aut-affil-num=6 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=伴場主一 kn-aut-sei=伴場 kn-aut-mei=主一 aut-affil-num=7 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=渡邊敦之 kn-aut-sei=渡邊 kn-aut-mei=敦之 aut-affil-num=8 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=藤尾栄起 kn-aut-sei=藤尾 kn-aut-mei=栄起 aut-affil-num=9 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=宮地克維 kn-aut-sei=宮地 kn-aut-mei=克維 aut-affil-num=10 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=永瀬聡 kn-aut-sei=永瀬 kn-aut-mei=聡 aut-affil-num=11 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=森田宏 kn-aut-sei=森田 kn-aut-mei=宏 aut-affil-num=12 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=斎藤博則 kn-aut-sei=斎藤 kn-aut-mei=博則 aut-affil-num=13 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=江森哲郎 kn-aut-sei=江森 kn-aut-mei=哲郎 aut-affil-num=14 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=浅沼幹人 kn-aut-sei=浅沼 kn-aut-mei=幹人 aut-affil-num=15 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=宮崎正博 kn-aut-sei=宮崎 kn-aut-mei=正博 aut-affil-num=16 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=中村陽一 kn-aut-sei=中村 kn-aut-mei=陽一 aut-affil-num=17 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=松原広己 kn-aut-sei=松原 kn-aut-mei=広己 aut-affil-num=18 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=伏見和郎 kn-aut-sei=伏見 kn-aut-mei=和郎 aut-affil-num=19 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=豊國伸哉 kn-aut-sei=豊國 kn-aut-mei=伸哉 aut-affil-num=20 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=大江透 kn-aut-sei=大江 kn-aut-mei=透 aut-affil-num=21 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=7 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=8 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=9 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=10 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=11 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=12 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=13 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=14 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 affil-num=15 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　神経情報学 affil-num=16 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　細胞生物学 affil-num=17 en-affil= kn-affil=松山市民病院循環器内科 affil-num=18 en-affil= kn-affil=国立病院岡山医療センター循環器科 affil-num=19 en-affil= kn-affil=北陸先端科学技術大学院大学ナノマテリアルテクノロジーセンター affil-num=20 en-affil= kn-affil=京都大学大学院医学研究科病態生物医学 affil-num=21 en-affil= kn-affil=岡山大学大学院医歯学総合研究科　循環器内科 en-keyword=4-Hydroxy-2-nonenal kn-keyword=4-Hydroxy-2-nonenal en-keyword=酸化ストレス kn-keyword=酸化ストレス en-keyword=心不全 kn-keyword=心不全 en-keyword=β遮断薬 kn-keyword=β遮断薬 END start-ver=1.4 cd-journal=joma no-vol=120 cd-vols= no-issue=2 article-no= start-page=159 end-page=168 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080801 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Examination of dialysis patients by a systematic review focused on serum phosphorus value kn-title=透析患者における至適血清リン値に関する文献による検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In November 2006, The Japanese Society for Dialysis Therapy (JSDT) announced its first guideline, "The guideline for the management of secondary hyperparathyroidism in chronic dialysis patients," which gives the recommended range of management target values, especially for serum phosphorus, corrected serum calcium and serum intact parathyroid hormone concentrations. Recent studies have suggested that these factors are independently associated with mortality, especially increased cardiovascular mortality. In this research we focused on the serum phosphorus concentration because it is the highest clinical factor among these three. We systematically reviewed almost all documents that discussed the relation between serum phosphorus concentration and mortality as well as the "range of the management target value" specified by foreign guidelines from the US, UK, Canada, Australia and other countries. We summarized the finding concerning the serum phosphorus value of dialysis patients (especially the upper bound value). As a result, it was found that the "range of the management target value" varied among these guidelines. The reasons for this variation likely included differences in the measurement day, in the categories of serum phosphorus concentration, and in the exposure conditions among the studies to which the guidelines referred. Moreover, it was concluded that the Japanese guideline announced by the JSDT should be updated based on the results of future studies. en-copyright= kn-copyright= en-aut-name=TsukijiMakoto en-aut-sei=Tsukiji en-aut-mei=Makoto kn-aut-name=築地淳 kn-aut-sei=築地 kn-aut-mei=淳 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院環境学研究科　生命環境学専攻　国際保健学分野 en-keyword=透析患者 (dialysis patients) kn-keyword=透析患者 (dialysis patients) en-keyword=血清リン値 (phosphatemia) kn-keyword=血清リン値 (phosphatemia) en-keyword=CKD-MBD kn-keyword=CKD-MBD en-keyword=ガイドライン (guideline) kn-keyword=ガイドライン (guideline) en-keyword=生命予後 (prognosis) kn-keyword=生命予後 (prognosis) en-keyword=JSDT kn-keyword=JSDT END start-ver=1.4 cd-journal=joma no-vol=120 cd-vols= no-issue=1 article-no= start-page=55 end-page=61 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080501 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Current standard of surgical treatment in gastrointesteinal cancers kn-title=X　消化管がんに対する現代の標準的治療　〜外科的治療を中心に〜 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NaomotoYoshio en-aut-sei=Naomoto en-aut-mei=Yoshio kn-aut-name=猶本良夫 kn-aut-sei=猶本 kn-aut-mei=良夫 aut-affil-num=1 ORCID= en-aut-name=YamatsujiTomoki en-aut-sei=Yamatsuji en-aut-mei=Tomoki kn-aut-name=山辻知樹 kn-aut-sei=山辻 kn-aut-mei=知樹 aut-affil-num=2 ORCID= en-aut-name=ShirakawaYasuhiro en-aut-sei=Shirakawa en-aut-mei=Yasuhiro kn-aut-name=白川靖博 kn-aut-sei=白川 kn-aut-mei=靖博 aut-affil-num=3 ORCID= en-aut-name=TakaokaMunenori en-aut-sei=Takaoka en-aut-mei=Munenori kn-aut-name=高岡宗徳 kn-aut-sei=高岡 kn-aut-mei=宗徳 aut-affil-num=4 ORCID= en-aut-name=FujiwaraYasuhiro en-aut-sei=Fujiwara en-aut-mei=Yasuhiro kn-aut-name=藤原康宏 kn-aut-sei=藤原 kn-aut-mei=康宏 aut-affil-num=5 ORCID= en-aut-name=TanabeShunsuke en-aut-sei=Tanabe en-aut-mei=Shunsuke kn-aut-name=田辺俊介 kn-aut-sei=田辺 kn-aut-mei=俊介 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　消化器・腫瘍外科学 en-keyword=消化管がん kn-keyword=消化管がん en-keyword=標準治療 kn-keyword=標準治療 en-keyword=食道がん kn-keyword=食道がん en-keyword=胃がん kn-keyword=胃がん en-keyword=大腸がん kn-keyword=大腸がん END start-ver=1.4 cd-journal=joma no-vol=120 cd-vols= no-issue=1 article-no= start-page=29 end-page=34 dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080501 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Statins inhibit hepatitis C virus RNA replication in human hepatoma cells kn-title=培養肝細胞を用いたスタチン剤のＣ型肝炎ウイルス抑制効果について en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=IkedaMasanori en-aut-sei=Ikeda en-aut-mei=Masanori kn-aut-name=池田正徳 kn-aut-sei=池田 kn-aut-mei=正徳 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科　分子生物学 en-keyword=HCV kn-keyword=HCV en-keyword=レプリコン kn-keyword=レプリコン en-keyword=スタチン kn-keyword=スタチン en-keyword=HMG-CoA reductase kn-keyword=HMG-CoA reductase en-keyword=ゲラニルゲラニル化 kn-keyword=ゲラニルゲラニル化 END start-ver=1.4 cd-journal=joma no-vol=4 cd-vols= no-issue= article-no= start-page=23 end-page=25 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The first case of hairworm, Gordius sp. vomited from a domestic dog in Japan kn-title=犬から吐出されたハリガネムシGordius sp.の日本における第1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=An adult female hairworm was vomited from a domestic dog with a cough in Hiroshima Prefecture. The worm body was long and slender, measuring 42.5 cm in length and 1 mm in maximum width. The specimen showed microscopically the smooth cuticular without tuberculations. This case is the first record of Gordius sp. infection in a dog in Japan. en-copyright= kn-copyright= en-aut-name=ShimoeToshimitsu en-aut-sei=Shimoe en-aut-mei=Toshimitsu kn-aut-name=下江俊光 kn-aut-sei=下江 kn-aut-mei=俊光 aut-affil-num=1 ORCID= en-aut-name=HashiguchiMasahiro en-aut-sei=Hashiguchi en-aut-mei=Masahiro kn-aut-name=橋口正大 kn-aut-sei=橋口 kn-aut-mei=正大 aut-affil-num=2 ORCID= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=3 ORCID= en-aut-name=MorishigeKazuhisa en-aut-sei=Morishige en-aut-mei=Kazuhisa kn-aut-name=森重和久 kn-aut-sei=森重 kn-aut-mei=和久 aut-affil-num=4 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 affil-num=2 en-affil= kn-affil=岡山大学 affil-num=3 en-affil= kn-affil=岡山大学 affil-num=4 en-affil= kn-affil=岡山大学 affil-num=5 en-affil= kn-affil=岡山大学 en-keyword=Gordius kn-keyword=Gordius en-keyword=hairworm kn-keyword=hairworm en-keyword=dog kn-keyword=dog END start-ver=1.4 cd-journal=joma no-vol=4 cd-vols= no-issue= article-no= start-page=19 end-page=21 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of Mesocestoides sp. infection in a domestic cat kn-title=飼い猫に寄生した有線条虫Mesocestoides sp.の1症例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 2-year-old domestic cat discharged 2 small cestode segments (1mm × 1mm) into the stool on 16th in March, 1993. On the next day, 4 cestode strobilae without scolex were obtained from this cat by administration of praziquantel (30mg/kg). Strobilae measured approximately 60-86mm in length and 1mm in maximum width. In each immature segment, the number of testes was more than 60. A paruterus measuring 316-473μm × 316-371μm was situated at the rear central part of each gravid segment. The eggs (32 × 24μm) in the paruterus contained oncosphers. These Mesocestoides Cestoda were not identified as M.lineatus or M. literatus for lack of their scoleces. en-copyright= kn-copyright= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=1 ORCID= en-aut-name=MorishigeKazuhisa en-aut-sei=Morishige en-aut-mei=Kazuhisa kn-aut-name=森重和久 kn-aut-sei=森重 kn-aut-mei=和久 aut-affil-num=2 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=斎藤獣医科病院 affil-num=2 en-affil= kn-affil=岡山大学医学部寄生虫学教室 affil-num=3 en-affil= kn-affil=岡山大学医療技術短期大学部一般教育 en-keyword=Mesocestoides sp. kn-keyword=Mesocestoides sp. en-keyword=domestic cat kn-keyword=domestic cat en-keyword=Fukuyama City kn-keyword=Fukuyama City END start-ver=1.4 cd-journal=joma no-vol=3 cd-vols= no-issue= article-no= start-page=41 end-page=42 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The extraction of a fishfook and the treatment of heterophyiasis in a cat kn-title=猫における有害異形吸虫の治療と針の摘出例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A domestic cat took a fish with a fishhook. She was infected with Hetelophyes hetelophyes nocens and had loose bowels. The fishhook was extracted from feline stomach using a flexible-alligator extractor. The hypodermic injection of praziquantel (30mg/kg) was successful for the treatment of this parasite. en-copyright= kn-copyright= en-aut-name=MorishigeKazuhisa en-aut-sei=Morishige en-aut-mei=Kazuhisa kn-aut-name=森重和久 kn-aut-sei=森重 kn-aut-mei=和久 aut-affil-num=1 ORCID= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=2 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部寄生虫学教室 affil-num=2 en-affil= kn-affil=斎藤獣医科病院 affil-num=3 en-affil= kn-affil=岡山大学医療技術短期大学部一般教育 en-keyword=heterophyiasis kn-keyword=heterophyiasis en-keyword=praziquantel kn-keyword=praziquantel en-keyword=cat kn-keyword=cat END start-ver=1.4 cd-journal=joma no-vol=3 cd-vols= no-issue= article-no= start-page=37 end-page=39 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Efficacy of praziquantel against Clonorchis sinensis infection in dogs and cats. kn-title=Praziquantelによる犬・猫の肝吸虫症の実験的治療 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The efficacy of praziquantel was tested using 11 dogs and 3 cats infected with Clonorchis sinensis. Each experimental animal was infected with 50 metacercariae of Clonorchis sinensis respectively. The efficacy of the drug was evaluated by considerable reductions of EPG. The worms were eliminated from 91% of dogs and 100% of cats with hypodermic injection of total 75mg/kg praziquantel. This drug was effective against Clonorchis sinensis infection in dogs and cats as in the case of other trematodes. en-copyright= kn-copyright= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=1 ORCID= en-aut-name=MorishigeKazuhisa en-aut-sei=Morishige en-aut-mei=Kazuhisa kn-aut-name=森重和久 kn-aut-sei=森重 kn-aut-mei=和久 aut-affil-num=2 ORCID= en-aut-name=KawasakiShinji en-aut-sei=Kawasaki en-aut-mei=Shinji kn-aut-name=川崎伸二 kn-aut-sei=川崎 kn-aut-mei=伸二 aut-affil-num=3 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=斎藤獣医科病院 affil-num=2 en-affil= kn-affil=岡山大学医学部寄生虫学教室 affil-num=3 en-affil= kn-affil=川崎動物病院 affil-num=4 en-affil= kn-affil=岡山大学医療技術短期大学部一般教育 en-keyword=praziquantel kn-keyword=praziquantel en-keyword=Clonorchis sinensis kn-keyword=Clonorchis sinensis en-keyword=dog kn-keyword=dog en-keyword=cat kn-keyword=cat END start-ver=1.4 cd-journal=joma no-vol=7 cd-vols= no-issue=2 article-no= start-page=215 end-page=217 dt-received= dt-revised= dt-accepted= dt-pub-year=1997 dt-pub=19970131 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A human case of Thelazia callipaeda infection in a 3-year old children in Fukuyama City, Hiroshima Prefecture kn-title=福山市で見い出された東洋眼虫の人体寄生例 en-subtitle= kn-subtitle= en-abstract=A case of eye infection of Thelazia callipaeda was observed in a 3-year old children in Fukuyama City, Hiroshima Prefecture in 1995. He had a pain or feeling like a foreign object in his right eye. A total of 2 adults Thelazia callipaeda (male and female) was recovered from theconjunctival sac by an oculist. The symptoms were went out after the removal of the worms. kn-abstract=東洋眼虫の人体寄生例は関東以西で、おもに九州から報告されてきた。中国地方におけるこの寄生虫の人体症例は下田ら(1))が第1例を、Miura et al. (2))が第2例をいずれも岡山県から報告しているだけである。今回福山市で初めて人体症例に遭遇したので報告する。 en-copyright= kn-copyright= en-aut-name=OchiTsuneto en-aut-sei=Ochi en-aut-mei=Tsuneto kn-aut-name=越智常登 kn-aut-sei=越智 kn-aut-mei=常登 aut-affil-num=1 ORCID= en-aut-name=KusauraJunko en-aut-sei=Kusaura en-aut-mei=Junko kn-aut-name=草浦潤子 kn-aut-sei=草浦 kn-aut-mei=潤子 aut-affil-num=2 ORCID= en-aut-name=KobayashiTakako en-aut-sei=Kobayashi en-aut-mei=Takako kn-aut-name=小林孝子 kn-aut-sei=小林 kn-aut-mei=孝子 aut-affil-num=3 ORCID= en-aut-name=SaitoTetsuro en-aut-sei=Saito en-aut-mei=Tetsuro kn-aut-name=斎藤哲郎 kn-aut-sei=斎藤 kn-aut-mei=哲郎 aut-affil-num=4 ORCID= en-aut-name=TonguYasumasa en-aut-sei=Tongu en-aut-mei=Yasumasa kn-aut-name=頓宮廉正 kn-aut-sei=頓宮 kn-aut-mei=廉正 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=越智眼科昭和町医院 affil-num=2 en-affil= kn-affil=福山市医師会総合健診センター affil-num=3 en-affil= kn-affil=福山市医師会捻合総合センター affil-num=4 en-affil= kn-affil=斎藤獣医科病院 affil-num=5 en-affil= kn-affil=岡山大学医療技術短期大学部 en-keyword=東洋眼虫 (Thelazia callipaeda) kn-keyword=東洋眼虫 (Thelazia callipaeda) en-keyword=人体症例 (human case) kn-keyword=人体症例 (human case) en-keyword=福山市 (Fukuyama City) kn-keyword=福山市 (Fukuyama City) END start-ver=1.4 cd-journal=joma no-vol=63 cd-vols= no-issue=1 article-no= start-page=231 end-page=242 dt-received= dt-revised= dt-accepted= dt-pub-year=1983 dt-pub=1983 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=頓阿の自筆懐紙・短冊・書状集成 en-subtitle= kn-subtitle= en-abstract= kn-abstract=南北朝期に為世門の四天王として歌壇に活躍した歌僧頓阿には正・続の「草庵和歌集」なる家集が現存し、そこには約二〇〇〇首に近い和歌が収録されている。頓阿の歌は、この家集のほかに、百首歌が幾種類かあり、また、勅撰集、私撰集、歌合などにも散見される。斎藤彰氏は、すでに頓阿の詠歌資料の中で信頼できるものを整理し、二一四六首と一〇一句を集計されているが、本稿では、そこで触れられなかった、頓阿の自筆の懐紙、短冊などを中心に、これまで収集したものを紹介、検討してみたい。（但し、後述するもののうち、「高野山金剛三昧院奉納短冊和歌」と大山祇神社蔵「詠三首和歌」のふたつは、斎藤氏も集計に加えられている。） en-copyright= kn-copyright= en-aut-name=InadaToshinori en-aut-sei=Inada en-aut-mei=Toshinori kn-aut-name=稲田利徳 kn-aut-sei=稲田 kn-aut-mei=利徳 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19920328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=火山岩斑晶中の微小ガラス包有物の分析によるマグマ中の水および二酸化炭素濃度の直接測定―レーザープロープ法の開発と応用― kn-title=LASER MICROPROBE ANALYSIS OF CARBON DIOXIDE AND WATER IN GLASS INCLUSION: AN ATTEMPT TO DETERMINE THEIR CONCENTRATIONS IN PRE-ERUPTIVE MAGMA en-subtitle= kn-subtitle= en-abstract= kn-abstract=Volatile materials dissolved in magmlas play an important role in the evolution of magmas and volcanic eruptions. During magma ascent, the magma may be saturated with the volatiles because of decrease in solubilities of the volatiles in silicate melts with pressure. Formation of a gas phase would lead to decrease in the bulk density of magma and thereby accelerate the magma ascent. Expansion of the resulting gas phase may induce a volcanic eruption. The major volatile components in a nlagma are H(2)0, C0(2), S and Cl. Glass inclusions in phenocrysts are the most suitable samples for measuring volatile concentrations in pre-eruptive magmas. However, it has been difficult to measure the H(2)0 and CO(2) concentrations in glass inclusions, mainly because the size of the glass inclusions is very small (50-200 μm) and the sensitivity of analytical methods is not　sufficient. In this study, we have developed a laser microprobe　technique for determining a minute amount of H(2)0 and C0(2) dissolved in glass inclusions. The analytical system consisting of a Nd-YAG laser for selective heating of glass inclusions and a gas chromatograph-mass spectrometer for measuring a micro quantity of H(2)0 and C0(2) dissolved in glass inclusions. The H(2)0 and C0(2) were extracted from glass inclusions by laser heating under a vacuum. The extracted gas was collected in a cold trap and then introduced to GCMS by carrier gas. Gas concentration was calculated from the absolute amount of the extracted gas and the mass of glass melted. The optimum working conditions (lamp current, pulse frequency and shooting duration) of laser extraction were decided using a basaltic glass sample. A glass sample ground to less than 100 μm thick was pierced by a laser beam and measured for diameter of the hole produced to obtain the accurate determination of the volume of the glass melted. The mass of the melted glass was calculated from its volume and density. Efforts were made for reduction of background level of C0(2) and H(2)0. High purity helium carrier gas was farther purified with cold traps to remove C0(2) and H(2)0 contained in the carrier gas. Analytical line was thoroughly baked out at 300℃ before the analyses. With these procedures, the blank C0(2) was reduced to less than 0.07 ng and the blank H(2)0 to less than 6 ng. The detection limit of the present system was found to be 0.15 ng C0(2) and 15 ng H(2)0, considering the confidence limit of the calibration. The repeated analyses of C0(2) in basaltic glass indicate that the present technique allows us to analyze C0(2) concentration of glass inclusions as small as 70 μm in diameter within an accuracy of ±60 ppm, assuming that the glass inclusion contains 300 ppm C0(2). The H(2)0 analyses of the glass by the present technique gave significantly lower H(2)0 concentration than the bulk analysis, suggesting incomplete degassing of H(2)0 from molten glass during laser irradiation due probably to its slow diffusion rate. The glass inclusion samples from Killauea volcano, Hawaii, and Izu-Oshima volcano, Japan, were analyzed to determine CO(2) concentrations of pre-eruptive magma. The C0(2) concentration of pre-eruptive magma in South-West Rift Zone of Kilauea volcano was 230 ppm. This suggests that the magma has been significantly degassed during its storage in the summit magma chamber and migration to the rift system. The depth of the magma chamber was estimated to be 2.8-4.0 km from the C0(2) concentration of the pre-eruptive magma, in good agreement with the geophysical estimation. Comparison of the volatile budget of Kilauea volcano based on the C0(2) analysis of glass inclusion with the observed C0(2) flux suggests that parental magma contains 3000 ppm C0(2). The bulk density of magma containing exsolved gases is not snlall enough to ascend to the surface by its own buoyancy. This is consistent with the present settings of the Kilauean magma; the sumrnit magma chamber and rift magma system extending from the summit caldera. The C0(2) concentration of pre-eruptive magma of Izu-Oshima volcano was found to be 1 70 ppm. The measured C0(2) concentration indicates that the magma chamber exists at a depth of about 2 km beneath the volcano. At this depth, the magma should be saturated with C0(2). The estimated bulk densities of the magma (d=2.4-2.6 g/c?) containing C0(2)-rich gas phase are consistent with the density structure of the volcano, if the magma before degassing contains C0(2) more than 1700 ppm. The rate of magma supply was estimated from the C0(2) concentration of pre-eruptive magma and C0(2) fluxes based on measurements on surface volcanic gases. Assuming the primary magma contains 2500 ppm C0(2), the estimated rate of magma supply(6-19x 10(3) tons/day) is compatible with the observed rate of magma supply based on the total mass of ejecta of major eruptions during the last 1500 years. en-copyright= kn-copyright= en-aut-name=SaitoGenji en-aut-sei=Saito en-aut-mei=Genji kn-aut-name=斎藤元治 kn-aut-sei=斎藤 kn-aut-mei=元治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=マイクロマグネテｨックモデルを用いた磁気記録解析のための数値計算法に関する研究 kn-title=Study on Numerical Techniques for Magnetic Recording Analysis Using Micromagnetic Model en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=斎藤郁夫 kn-aut-sei=斎藤 kn-aut-mei=郁夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1976 dt-pub=19760630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=正常犬および実験的冠動脈硬化犬の心血行動態に与える,冠拡張剤の影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=斎藤大治 kn-aut-sei=斎藤 kn-aut-mei=大治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=上皮細胞基底膜におけるマウスα5(IV)とα6(IV)コラーゲン遺伝子の多様な発現 kn-title=Differential Expression of Mouse α5(IV) and α6(IV) Collagen Genes in Epithelial Basement Membranes en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=斎藤健司 kn-aut-sei=斎藤 kn-aut-mei=健司 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1984 dt-pub=19841231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=妊娠ラットの体液中ポリアミンの変動に関する研究 kn-title=Alterations of Polyamines in Body Fluids during Pregnancy in Rats en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=斎藤央 kn-aut-sei=斎藤 kn-aut-mei=央 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END