β(2)-microglobulinの測定値に関する研究 第1報 高校生の血清β(2)-microglobulin値の分布型と統計値及び尿中β(2)-microglobulinの測定値について

The serum β(2)-microglobulin levels of 112 senior high school students were determined by radioimmunoassay and were analyzed statistically. Its measured values were transformed into logarithms and the distribution type was decided and also mean values. (m), standard deviation (SD), 95% confidence intervals and 5% rejection limit of logarithm transformed values and the actual values were calculated. The urinary β(2)-microglobulin levels of 18 senior high school students were statistically analyzed, and its measured values were transformed into logarithms and then the same calculations were performed. The results obtained were as follows: 1. The distribution type of the serum β(2)-microglobulin level was adapted by x(2)-test to the log normal type rather than to the normal distribution. 2. The statistical values of the serum β(2)-microglobulin, as they are adapted to the log normal type, were as follows: The logarithm transformed mean value was 0.158 mg/l, m±SD (logarithm) was 0.158±0.088 mg/l, m±2SD was -0.018-0.334 mg/l, 95% confidence interval was 0.142-0.175 mg/l and 5% rejection limit was -0.335 (upper) mg/l. The actual mean value (antilog) was 1.44 mg/l, m±SD (antilog) was 1.44±0.82 mg/l, m±2SD (antilog) was 0.96-2.16mg/l, 95% confidence interval was 1.39-1.50 mg/l and 5% rejection limit (upper) was 2.16 mg/l. 3. The statistical values of urinary β(2)-microglobulin, as adapted to the log normal type, were as follows: The logarithm transformed mean value was 2.114 μg/l, m±SD (logarithm) was 2.114±0.179 μg/l, m±2SD (logarithm) was 1.758-2.472 μg/l, 95% confidence interval (logarithm) was 2.023-2.205 μg/l and 5% rejection limit (upper, logarithm) was 2.513 μg/l. The actual mean value (antilog) was 130 μg/l, m±SD (antilog) was 130±1.51 μg/l, m±2SD (antilog) was 57.3-296 μg/l, 95% confidence interval (antilog) was 105-160 μg/l and 5% rejection limit (upper, antilog) was 326 μg/l.