| ID | 16727 |
| Eprint ID | 16727
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| FullText URL | |
| Title Alternative | Studies on the Alternative Pathway in Systemic Lupus Erythematosus Using Rabbit Red Blood Cells Part 1. Fundamental Studies
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| Author |
Miyashima, Hiroto
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| Abstract | Methods of measuring the activity of the total alternative complement pathway, properdin and Factor B with rabbit red blood cells(RaRBC) were examined. The following results were obtained. 1) 0.03M EGTA-GVB permitted activation of the alternative complement pathway without activation of the classical complement pathway. 2) RaRBC were hemolysed by C4/C2 depleted serum as well as by normal serum. RaRBC were not hemolysed by inulin or zymosan treated serum. 3) The activity of the total alternative complement pathway was measured with 50 % hemolysis of RaRBC in EGTA-GVB, designated as ACH50. 4) The activity of properdin or Factor B was measured with RaRBC and normal fresh human serum deficient in properdin (RP) or deficient in Factor B (RB).
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| Keywords | 全身性エリテマトーデス
補体
alternative pathway総溶血活性
propendin活性
Factor B活性
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| Published Date | 1981-12-30
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| Publication Title |
岡山医学会雑誌
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| Publication Title Alternative | Journal of Okayama Medical Association
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| Volume | volume93
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| Issue | issue11-12
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| Publisher | 岡山医学会
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| Publisher Alternative | Okayama Medical Association
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| Start Page | 977
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| End Page | 985
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| ISSN | 0030-1558
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| NCID | AN00032489
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| Content Type |
Journal Article
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| Official Url | https://www.jstage.jst.go.jp/article/joma1947/93/11-12/93_11-12_977/_article/-char/ja/
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| Related Url | http://www.okayama-u.ac.jp/user/oma/index.html
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| language |
Japanese
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| Copyright Holders | 岡山医学会
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| File Version | publisher
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| Refereed |
True
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| Eprints Journal Name | joma
|
