Naito, Hiromichi - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Immediate and delayed effects of thermal stress on fever-associated seizures in children: A time-stratified case-crossover study in Japan

FullText URL	fulltext.pdf
Author	Matsumoto, Naomi\| Yamamura, Yuka\| Uraguchi, Kensuke\| Obara, Takafumi\| Naito, Hiromichi\| Yorifuji, Takashi\|
Keywords	Time-stratified Case-crossover study Thermal stress Fever-associated seizures Universal Thermal Climate Index (UTCI) Climate change Pediatric emergency
Published Date	2026-03
Publication Title	International Journal of Biometeorology
Volume	volume70
Issue	issue3
Publisher	Springer Science and Business Media LLC
Start Page	86
ISSN	0020-7128
NCID	AA00679987
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2026
File Version	publisher
PubMed ID	41784651
DOI	10.1007/s00484-026-03146-z
Web of Science KeyUT	001712219200002
Related Url	isVersionOf https://doi.org/10.1007/s00484-026-03146-z

Revisiting Adrenal Crisis Triggered by Influenza Infection: Lessons from Two Fatal Cases

JaLCDOI	10.18926/AMO/70458
FullText URL	80_2_153.pdf
Author	Ueda, Yoshiyuki\| Yumoto, Tetsuya\| Hongo, Takashi\| Obara, Takafumi\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Hasegawa, Kosei\| Futagawa, Natsuko\| Naito, Hiromichi\| Nakao, Atsunori\|
Abstract	Adrenal crisis is a life-threatening endocrine emergency that can progress within hours despite a prior diagnosis and maintenance therapy. We describe a fatal influenza-triggered adrenal crisis in two patients: a child with panhypopituitarism and an adult with prior pituitary surgery, both presenting in cardiac arrest. Despite resuscitation and intravenous hydrocortisone, a fatal hypoxic-ischemic injury or multiorgan failure occurred. These cases highlight the fulminant course of an adrenal crisis and underscore the importance of early recognition, clinician awareness, prompt parenteral hydrocortisone administration, and reinforcement of education for patients, caregivers, and healthcare providers to improve preparedness and prevent avoidable deaths.
Keywords	adrenal insufficiency cardiac arrest hydrocortisone influenza shock
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2026-04
Volume	volume80
Issue	issue2
Publisher	Okayama University Medical School
Start Page	153
End Page	157
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2026 by Okayama University Medical School
File Version	publisher
Refereed	True

Targeting the Gut in Sepsis: Therapeutic Potential of Medical Gases

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Obara, Takafumi\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	carbon monoxide gastrointestinal tract gut hydrogen hydrogen sulfide sepsis septic shock
Published Date	2026-01-28
Publication Title	Biomolecules
Volume	volume16
Issue	issue2
Publisher	MDPI AG
Start Page	199
ISSN	2218-273X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 by the authors.
File Version	publisher
PubMed ID	41750271
DOI	10.3390/biom16020199
Web of Science KeyUT	001700627500001
Related Url	isVersionOf https://doi.org/10.3390/biom16020199

Association Between Positive End-Expiratory Pressure at Venovenous Extracorporeal Membrane Oxygenation Initiation and Liberation Outcomes in Acute Respiratory Distress Syndrome: A Multicenter Retrospective Study

FullText URL	fulltext.pdf
Author	Hongo, Takashi\| Kosaki, Yoshinori\| Yumoto, Tetsuya\| Nishikimi, Mitsuaki\| Ohshimo, Shinichiro\| Shime, Nobuaki\| Nakao, Atsunori\| Naito, Hiromichi\|
Keywords	acute respiratory distress syndrome extracorporeal membrane oxygenation mechanical ventilation respiratory therapy weaning
Published Date	2026-02
Publication Title	Critical Care Explorations
Volume	volume8
Issue	issue2
Publisher	Ovid Technologies (Wolters Kluwer Health)
Start Page	e1375
ISSN	2639-8028
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 The Authors.
File Version	publisher
PubMed ID	41642671
DOI	10.1097/cce.0000000000001375
Web of Science KeyUT	001681791800001
Related Url	isVersionOf https://doi.org/10.1097/cce.0000000000001375

Association of Wet-Bulb Globe Temperature with heat-related illness hospitalizations in Japan: a time-stratified, case-crossover study

FullText URL	fulltext.pdf
Author	Yamamura, Yuka\| Hongo, Takashi\| Yumoto, Tetsuya\| Sasai, Fumiya\| Tokioka, Kohei\| Obara, Takafumi\| Nojima, Tsuyoshi\| Kanda, Jun\| Yokobori, Shoji\| Naito, Hiromichi\| Yorifuji, Takashi\| Nakao, Atsunori\|
Keywords	Wet-Bulb Globe Temperature Heat stroke Heat related illness Global warming
Published Date	2026-01-05
Publication Title	International Journal of Emergency Medicine
Volume	volume19
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	11
ISSN	1865-1380
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025.
File Version	publisher
PubMed ID	41491406
DOI	10.1186/s12245-025-01112-x
Web of Science KeyUT	001663188000001
Related Url	isVersionOf https://doi.org/10.1186/s12245-025-01112-x

Association of Carboxyhemoglobin With Severity and Outcomes in Hypothermic Patients: A Retrospective Cohort Study

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Author	Miyoshi, Yuya\| Yumoto, Tetsuya\| Hongo, Takashi\| Obara, Takafumi\| Nojima, Tsuyoshi\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	carbon monoxide carboxyhemoglobin heme oxygenase hypothermia sepsis
Published Date	2025-11-27
Publication Title	Cureus
Volume	volume17
Issue	issue11
Publisher	Springer Science and Business Media LLC
Start Page	e97962
ISSN	2168-8184
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Copyright 2025 Miyoshi et al.
File Version	publisher
PubMed ID	41458777
DOI	10.7759/cureus.97962
Related Url	isVersionOf https://doi.org/10.7759/cureus.97962

Characteristics of out-of-hospital cardiac arrest due to cerebrovascular disorders: a nationwide, retrospective, observational study

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Author	Ueda, Yoshiyuki\| Nojima, Tsuyoshi\| Obara, Takafumi\| Hongo, Takashi\| Yumoto, Tetsuya\| Tsukahara, Kohei\| Yorifuji, Takashi\| Nakao, Atsunori\| Naito, Hiromichi\|
Keywords	Cardiac arrest Cardiopulmonary resuscitation Cerebral hemorrhage Stroke Subarachnoid hemorrhage
Published Date	2025-11
Publication Title	Resuscitation Plus
Volume	volume26
Publisher	Elsevier BV
Start Page	101145
ISSN	2666-5204
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	41312446
DOI	10.1016/j.resplu.2025.101145
Web of Science KeyUT	001619366500001
Related Url	isVersionOf https://doi.org/10.1016/j.resplu.2025.101145

Long intervals between repetitive concussions reduce risk of cognitive impairment and limit microglial activation, astrogliosis, and tauopathy in adolescent rats

FullText URL	fulltext.pdf
Author	Hirata, Yuichi\| Kin, Kyohei\| Nagase, Takayuki\| Sasaki, Tatsuya\| Sasada, Susumu\| Sugahara, Chiaki\| Hirayama, Takahiro\| Kawai, Koji\| Tanimoto, Shun\| Miyake, Hayato\| Saijo, Tomoya\| Naito, Hiromichi\| Masai, Kaori\| Yasuhara, Takao\| Tanaka, Shota\|
Keywords	Concussion Return to play Sports-related head injury Microglia Astrocyte Tauopathy
Published Date	2025-11-18
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	40522
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	41254121
DOI	10.1038/s41598-025-24376-y
Web of Science KeyUT	001618576200030
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-24376-y

Hydrogen-rich gas enhances mitochondrial membrane potential and respiratory function recovery in Caco-2 cells post-ischemia-reperfusion injury

FullText URL	fulltext.pdf
Author	Seya, Mizuki\| Aokage, Toshiyuki\| Meng, Ying\| Hirayama, Takahiro\| Obara, Takafumi\| Nojima, Tsuyoshi\| Yoshinori, Kosaki\| Yumoto, Tetsuya\| Watanabe, Akihiro\| Yamada, Taihei\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	Intestinal ischemia-reperfusion injury Molecular hydrogen Hydrogen gas therapy Caco-2 cells Mitochondrial function Hypoxia-inducible factor-1α (HIF1α)
Published Date	2025-10
Publication Title	Biochemical and Biophysical Research Communications
Volume	volume786
Publisher	Elsevier BV
Start Page	152753
ISSN	0006-291X
NCID	AA00564395
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Authors.
File Version	publisher
PubMed ID	41043278
DOI	10.1016/j.bbrc.2025.152753
Web of Science KeyUT	001588631300004
Related Url	isVersionOf https://doi.org/10.1016/j.bbrc.2025.152753

Successful Transplantation of Multiple Organs from Donor after Helium Asphyxiation: First Case Report in Japan

FullText URL	fulltext.pdf
Author	Jinno, Shunta\| Hongo, Takashi\| Obara, Takafumi\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Yumoto, Tetsuya\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	brain death heart arrest helium
Published Date	2025-04-28
Publication Title	JMA Journal
Volume	volume8
Issue	issue2
Publisher	Japan Medical Association
Start Page	650
End Page	653
ISSN	2433-3298
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Japan Medical Association
File Version	publisher
PubMed ID	40416025
DOI	10.31662/jmaj.2024-0395
Web of Science KeyUT	001450822700001
Related Url	isVersionOf https://doi.org/10.31662/jmaj.2024-0395

Tattoo-associated toxic shock syndrome: a case report

FullText URL	fulltext.pdf
Author	Kubo, Takuya\| Yumoto, Tetsuya\| Hagiya, Hideharu\| Iio, Koji\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	Blood culture Critically ill Septic shock Tattooing Toxic shock syndrome
Published Date	2025-10-01
Publication Title	International Journal of Emergency Medicine
Volume	volume18
Issue	issue1
Publisher	Springer Science and Business Media LLC
Start Page	185
ISSN	1865-1380
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025.
File Version	publisher
PubMed ID	41034788
DOI	10.1186/s12245-025-00993-2
Web of Science KeyUT	001586543500001
Related Url	isVersionOf https://doi.org/10.1186/s12245-025-00993-2

Compression only CPR and mortality in pediatric out-of-hospital cardiac arrest during COVID-19 pandemic

FullText URL	fulltext.pdf
Author	Obara, Takafumi\| Naito, Hiromichi\| Matsumoto, Naomi\| Tsukahara, Kohei\| Hongo, Takashi\| Nojima, Tsuyoshi\| Yumoto, Tetsuya\| Yorifuji, Takashi\| Nakao, Atsunori\|
Keywords	Cardiopulmonary resuscitation Out-of-hospital Pediatrics Artificial respiration COVID-19 pandemic
Published Date	2025-10
Publication Title	Resuscitation
Volume	volume215
Publisher	Elsevier BV
Start Page	110706
ISSN	0300-9572
NCID	AA00817253
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	40619060
DOI	10.1016/j.resuscitation.2025.110706
Web of Science KeyUT	001534174600001
Related Url	isVersionOf https://doi.org/10.1016/j.resuscitation.2025.110706

Mid-term (30- to 90-day) neurological changes in out-of-hospital cardiac arrest survivors receiving extracorporeal cardiopulmonary resuscitation: a nationwide retrospective study (the JAAM-OHCA registry)

FullText URL	fulltext.pdf
Author	Hongo, Takashi\| Yumoto, Tetsuya\| Nojima, Tsuyoshi\| Obara, Takafumi\| Ueda, Yoshiyuki\| Yorifuji, Takashi\| Nakao, Atsunori\| Naito, Hiromichi\|
Keywords	Post-cardiac arrest syndrome Cardiac arrest ECPR Patient outcome assessment Prognostication Venoarterial ECMO
Published Date	2025-09
Publication Title	Resuscitation Plus
Volume	volume25
Publisher	Elsevier BV
Start Page	101057
ISSN	2666-5204
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	40978708
DOI	10.1016/j.resplu.2025.101057
Web of Science KeyUT	001561245500001
Related Url	isVersionOf https://doi.org/10.1016/j.resplu.2025.101057

Neurological outcomes with hypothermia versus normothermia in patients with moderate initial illness severity following resuscitation from out-of-hospital cardiac arrest: protocol for a multicentre randomised controlled trial (R-CAST OHCA)

FullText URL	fulltext.pdf
Author	Naito, Hiromichi\| Nishikimi, Mitsuaki\| Okada, Yohei\| Maeyama, Hiroki\| Kiguchi, Takeyuki\| Yorifuji, Takashi\| Nishida, Kazuki\| Matsui, Shigeyuki\| Kuroda, Yasuhiro\| Nishiyama, Kei\| Iwami, Taku\| Nakao, Atsunori\| JAAM R-CAST OHCA Trial Group\|
Published Date	2025-08
Publication Title	BMJ Open
Volume	volume15
Issue	issue8
Publisher	BMJ
Start Page	e101809
ISSN	2044-6055
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Author(s) (or their employer(s)) 2025.
File Version	publisher
PubMed ID	40846339
DOI	10.1136/bmjopen-2025-101809
Web of Science KeyUT	001559038200001
Related Url	isVersionOf https://doi.org/10.1136/bmjopen-2025-101809

Organ Donation after Extracorporeal Cardiopulmonary Resuscitation: Clinical and Ethical Perspectives

JaLCDOI	10.18926/AMO/69147
FullText URL	79_4_221.pdf
Author	Yumoto, Tetsuya\| Naito, Hiromichi\| Hongo, Takashi\| Obara, Takafumi\| Kosaki, Yoshinori\| Ageta, Kohei\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Nakao, Atsunori\|
Abstract	Extracorporeal cardiopulmonary resuscitation (ECPR) has evolved into a life-saving therapy for select cardiac arrest patients, yet a growing body of evidence suggests it also holds promise as a bridge to organ donation in non-survivors. This review explores the clinical outcomes, ethical complexities, and evolving policies surrounding organ donation after ECPR. We summarize recent international and Japanese data demonstrating favorable graft function from ECPR donors, with the exception of lung transplantation. The ethical challenges — particularly those involving brain death determination on extracorporeal membrane oxygenation and adherence to the dead donor rule — are discussed in the context of Japan’s recent regulatory reforms. Additionally, we highlight the importance of structured end-of-life communication through multidisciplinary team meetings in facilitating ethically sound transitions from rescue efforts to donation pathways. Moving forward, improvements in donor management, standardized legal frameworks, and public and professional education are essential to optimizing the life-saving and life-giving potential of ECPR.
Keywords	brain death end-of-life care ethical dilemmas extracorporeal cardiopulmonary resuscitation
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2025-08
Volume	volume79
Issue	issue4
Publisher	Okayama University Medical School
Start Page	221
End Page	229
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2025 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	40859438
Web of Science KeyUT	001566286400001

Association of emergency intensive care unit occupancy due to brain-dead organ donors with ambulance diversion

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Obara, Takafumi\| Hongo, Takashi\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Hisamura, Masaki\| Nakao, Atsunori\| Yorifuji, Takashi\| Naito, Hiromichi\|
Keywords	Ambulance diversion Bed occupancy Brain death Emergency medical services Intensive care units Organ donation
Published Date	2025-04-12
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Nature Portfolio
Start Page	12633
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40221631
DOI	10.1038/s41598-025-97198-7
Web of Science KeyUT	001466042000027
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-97198-7

Association of blood carboxyhemoglobin levels with mortality and neurological outcomes in out-of-hospital cardiac arrest

FullText URL	fulltext.pdf
Author	Hongo, Takashi\| Yumoto, Tetsuya\| Naito, Hiromichi\| Hiraoka, Tomohiro\| Murakami, Yuya\| Obara, Takafumi\| Nojima, Tsuyoshi\| Aokage, Toshiyuki\| Nakao, Atsunori\|
Keywords	brain injury carbon monoxide carboxyhemoglobin cardiac arrest resuscitation
Published Date	2025-03-23
Publication Title	Acute Medicine & Surgery
Volume	volume12
Issue	issue1
Publisher	Wiley
Start Page	e70053
ISSN	2052-8817
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	40130086
DOI	10.1002/ams2.70053
Web of Science KeyUT	001450042700001
Related Url	isVersionOf https://doi.org/10.1002/ams2.70053

Age-specific assessment of initial hemoglobin levels and shock index for predicting life-saving interventions in pediatric blunt liver and spleen injuries

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Obara, Takafumi\| Hongo, Takashi\| Iida, Atsuyoshi\| Tsukahara, Kohei\| Katsura, Morihiro\| Kondo, Yutaka\| Yasuda, Hideto\| Kushimoto, Shigeki\| Yorifuji, Takashi\| Naito, Hiromichi\| Nakao, Atsunori\| SHIPPs Study Group\|
Keywords	Abdominal injuries Blood transfusions Hemoglobin Hemostasis Shock index
Published Date	2025-03-12
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Nature Portfolio
Start Page	8502
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40074821
DOI	10.1038/s41598-025-92673-7
Web of Science KeyUT	001443941100009
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-92673-7

Undetermined Ruptured Low-Grade Appendiceal Mucinous Neoplasm Following High-Energy Blunt Abdominal Trauma Requiring Emergency Laparotomy

FullText URL	fulltext.pdf
Author	Matsuo, Ippei\| Yumoto, Tetsuya\| Tsuji, Akari\| Tanabe, Ryo\| Matsumura, Toshihisa\| Shimabara, Mikoto\| Akai, Masaaki\| Takagi, Shoji\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	abdominal injuries appendiceal neoplasms computed tomography mucinous pseudomyxoma peritonei
Published Date	2025-01-02
Publication Title	Clinical Case Reports
Volume	volume13
Issue	issue1
Publisher	Wiley
Start Page	e70071
ISSN	2050-0904
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	39759185
DOI	10.1002/ccr3.70071
Web of Science KeyUT	001388215700001
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Characteristics and outcomes of subarachnoid hemorrhage from vertebral artery dissection: A comparative study with other non-traumatic etiologies

FullText URL	fulltext.pdf
Author	Oshita, Shu\| Yumoto, Tetsuya\| Jinno, Shunta\| Matsuo, Ippei\| Hongo, Takashi\| Naito, Hiromichi\| Hiramatsu, Masafumi\| Haruma, Jun\| Sugiu, Kenji\| Tanaka, Shota\| Nakao, Atsunori\|
Keywords	headache intracranial aneurysm prodromal symptoms subarachnoid hemorrhage vertebral artery dissection
Published Date	2024-12-26
Publication Title	Acute Medicine & Surgery
Volume	volume11
Issue	issue1
Publisher	Wiley
Start Page	e70031
ISSN	2052-8817
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	39726641
DOI	10.1002/ams2.70031
Web of Science KeyUT	001384855300001
Related Url	isVersionOf https://doi.org/10.1002/ams2.70031