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ID 68913
Author
Fujii, Mayu Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University
Ueno, Nanaho Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University
Mitsudo, Koichi Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University ORCID Kaken ID publons researchmap
Sato, Eisuke Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University
Suga, Seiji Division of Applied Chemistry, Graduate School of Environmental, Life, Natural Science and Technology, Okayama University ORCID Kaken ID researchmap
Abstract
An electrochemical method was developed to convert α,β-unsaturated aldehydes into carboxylic acid derivatives via cyanosilylation, isomerization, and nucleophilic addition. This reaction is more sustainable than the usual electrochemical organic reaction because this reaction proceeds catalytically with active species generated by a very small amount of electricity. Furthermore, scale-up synthesis with a flow reactor has been achieved.
Note
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.5c01790.
This fulltext file will be available in Jun. 2026.
Published Date
2025-06-23
Publication Title
Organic Letters
Publisher
American Chemical Society (ACS)
ISSN
1523-7060
NCID
AA11347843
Content Type
Journal Article
language
English
OAI-PMH Set
岡山大学
Copyright Holders
© 2025 American Chemical Society
File Version
author
PubMed ID
DOI
Related Url
isVersionOf https://doi.org/10.1021/acs.orglett.5c01790
Funder Name
Japan Society for the Promotion of Science
Ministry of Education, Culture, Sports, Science and Technology
助成番号
22K05115
22H02122
23K13748
21H05214