Matsukawa, Akihiro - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Expression of Spred2 in the urothelial tumorigenesis of the urinary bladder

FullText URL	fulltext.pdf
Author	Oda, Shinsuke\| Fujisawa, Masayoshi\| Li, Chunning\| Ito, Toshihiro\| Yamaguchi, Takahiro\| Yoshimura, Teizo\| Matsukawa, Akihiro\|
Published Date	2021-11-24
Publication Title	Plos One
Volume	volume16
Issue	issue11
Publisher	Public Library Science
Start Page	e0254289
ISSN	1932-6203
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 Oda et al.
File Version	publisher
PubMed ID	34818323
DOI	10.1371/journal.pone.0254289
Web of Science KeyUT	000747234800004
Related Url	isVersionOf https://doi.org/10.1371/journal.pone.0254289

Spred2 controls the severity of Concanavalin A-induced liver damage by limiting interferon-gamma production by CD4(+) and CD8(+) T cells

FullText URL	fulltext.pdf
Author	Sun, Cuiming\| Fujisawa, Masayoshi\| Ohara, Toshiaki\| Liu, Qiuying\| Cao, Chen\| Yang, Xu\| Yoshimura, Teizo\| Kunkel, Steven L.\| Matsukawa, Akihiro\|
Keywords	Liver damage MAPK Signal transduction and regulation Gene-modified mice Spred2
Published Date	2022-01
Publication Title	Journal Of Advanced Research
Volume	volume35
Publisher	Elsevier
Start Page	71
End Page	86
ISSN	2090-1232
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Authors.
File Version	publisher
PubMed ID	35003795
DOI	10.1016/j.jare.2021.03.014
Web of Science KeyUT	000736947300007
Related Url	isVersionOf https://doi.org/10.1016/j.jare.2021.03.014

Crosstalk between Cancer Cells and Fibroblasts for the Production of Monocyte Chemoattractant Protein-1 in the Murine 4T1 Breast Cancer

FullText URL	fulltext.pdf
Author	Imamura, Mayu\| Li, Tiantian\| Li, Chunning\| Fujisawa, Masayoshi\| Mukaida, Naofumi\| Matsukawa, Akihiro\| Yoshimura, Teizo\|
Keywords	breast cancer chemokine lung metastasis fibroblasts macrophages tumor microenvironment
Published Date	2021-10-22
Publication Title	Current Issues In Molecular Biology
Volume	volume43
Issue	issue3
Publisher	MDPI
Start Page	1726
End Page	1740
ISSN	1467-3037
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	34698088
DOI	10.3390/cimb43030122
Web of Science KeyUT	000735852200001
Related Url	isVersionOf https://doi.org/10.3390/cimb43030122

PolyI:C suppresses TGF-β1-induced Akt phosphorylation and reduces the motility of A549 lung carcinoma cells

FullText URL	fulltext20210824-3.pdf
Author	Yamaguchi, Takahiro\| Yoshimura, Teizo\| Ohara, Toshiaki\| Fujisawa, Masayoshi\| Tong, Gao\| Matsukawa, Akihiro\|
Keywords	Toll-like receptors cell migration metastasis epithelial mesenchymal transformation
Note	This is a post-peer-review, pre-copyedit version of an article published in Molecular Biology Reports. The final authenticated version is available online at: https://doi.org/10.1007/s11033-021-06625-1\|
Published Date	2021-8-14
Publication Title	Molecular Biology Reports
Publisher	Springer Science and Business Media LLC
ISSN	0301-4851
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	34390443
DOI	10.1007/s11033-021-06625-1
Web of Science KeyUT	000684897400002
Related Url	isVersionOf https://doi.org/10.1007/s11033-021-06625-1

Utility of gastric biopsy in diagnosing IgG4‐related gastrointestinal disease

FullText URL	fulltext.pdf Figures.pdf Tables_Figure_legends.pdf
Author	Uchino, Kaori\| Notohara, Kenji\| Uehara, Takeshi\| Kuraishi, Yasuhiro\| Itakura, Junya\| Matsukawa, Akihiro\|
Keywords	biopsy feasibility studies gastric mucosa gastritis IgG4 IgG4‐related disease immunoglobulin G4 immunohistochemistry plasma cells
Note	This is the peer reviewed version of the following article: Kaori Uchino et. al. Utility of gastric biopsy in diagnosing IgG4‐related gastrointestinal disease. Pathology International (2020), which has been published in final form at [https://doi.org/10.1111/pin.13059. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This fulltext is available in Jan. 2022.\|
Published Date	2020-12-30
Publication Title	Pathology International
Volume	volume71
Issue	issue2
Publisher	Wiley
Start Page	124
End Page	134
ISSN	1320-5463
NCID	AA10984364
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	33378576
DOI	10.1111/pin.13059
Web of Science KeyUT	000603493000001
Related Url	isVersionOf https://doi.org/10.1111/pin.13059

Spred2-deficiency enhances the proliferation of lung epithelial cells and alleviates pulmonary fibrosis induced by bleomycin

FullText URL	fulltext.pdf
Author	Kawara, Akina\| Mizuta, Ryo\| Fujisawa, Masayoshi\| Ito, Toshihiro\| Li, Chunning\| Nakamura, Kaoru\| Sun, Cuiming\| Kuwabara, Masaki\| Kitabatake, Masahiro\| Yoshimura, Teizo\| Matsukawa, Akihiro\|
Keywords	Cell signalling Mechanisms of disease
Published Date	2020-10-05
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature
Start Page	16490
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	33020583
DOI	10.1038/s41598-020-73752-3
Web of Science KeyUT	000577291800001
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-73752-3

Decreased miR-200b-3p in cancer cells leads to angiogenesis in HCC by enhancing endothelial ERG expression

FullText URL	fulltext.pdf
Author	Moh-Moh-Aung, Aye\| Fujisawa, Masayoshi\| Ito, Sachio\| Katayama, Hiroshi\| Ohara, Toshiaki\| Ota, Yoko\| Yoshimura, Teizo\| Matsukawa, Akihiro\|
Keywords	Molecular medicine Tumour angiogenesis
Published Date	2020-06-26
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature
Start Page	10418
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	32591615
DOI	10.1038/s41598-020-67425-4
Web of Science KeyUT	000545967200015
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-67425-4

Juvenile Granulosa Cell Tumor with an Unusual Clinical Course: A Late-onset and Late Recurrent Case

JaLCDOI	10.18926/AMO/58275
FullText URL	74_2_159.pdf
Author	Thar Htet San\| Ota, Yoko\| Fushimi, Soichiro\| Fujisawa, Masayoshi\| Yanai, Hiroyuki\| Toda, Hiroko\| Kunitomo, Tadayoshi\| Kodama, Keisuke\| Matsukawa, Akihiro\|
Abstract	Juvenile granulosa cell tumors (JGCTs) are rare ovarian tumors with overall good prognoses. They differ from adult granulosa cell tumors (AGCTs), which are well known for late recurrence. Most JGCTs (～97%) occur in individuals <30 years old. We report a recurrent JGCT in a 40-year-old woman 5 years after initial presentation. The histological appearance and lack of 402C>G missense point mutation of FOXL2 gene (characteristic of AGCT but absent in JGCT) allowed differentiation from AGCT. This is the first comprehensive report of JGCT with late recurrence. Although rare, late recurrence of JGCT can occur; long-term surveillance is suggested.
Keywords	juvenile granulosa cell tumor late recurrence adult granulosa cell tumor
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2020-04
Volume	volume74
Issue	issue2
Publisher	Okayama University Medical School
Start Page	159
End Page	163
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2020 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	32341591
Web of Science KeyUT	000528278500010
NAID	120006839454

Prolonged warm ischemia exacerbated acute rejection after lung transplantation from donation after cardiac death in a mouse

FullText URL	fulltext.pdf
Author	Hirano, Yutaka\| Sugimoto, Seiichiro\| Yamamoto, Sumiharu\| Okada, Masanori\| Otani, Shinji\| Ohara, Toshiaki\| Yamane, Masaomi\| Matsukawa, Akihiro\| Oto, Takahiro\| Toyooka, Shinichi\|
Keywords	Brain dead donor Donation after cardiac death Lung transplantation Organ preservation Rejection
Note	This is a post-peer-review, pre-copyedit version of an article published in General Thoracic and Cardiovascular Surgery. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11748-019-01181-9.\|
Published Date	2019-07-31
Publication Title	General Thoracic and Cardiovascular Surgery
Volume	volume68
Issue	issue1
Publisher	Springer
Start Page	57
End Page	62
ISSN	1863-6705
NCID	AA12201344
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	31367969
DOI	10.1007/s11748-019-01181-9
Web of Science KeyUT	000511499200009
Related Url	isVersionOf https://doi.org/10.1007/s11748-019-01181-9

Cancer Cell-Derived Granulocyte-Macrophage Colony-Stimulating Factor Is Dispensable for the Progression of 4T1 Murine Breast Cancer

FullText URL	fulltext.pdf
Author	Yoshimura, Teizo\| Nakamura, Kaoru\| Li, Chunning\| Fujisawa, Masayoshi\| Shiina, Tsuyoshi\| Imamura, Mayu\| Li, Tiantian\| Mukaida, Naofumi\| Matsukawa, Akihiro\|
Keywords	macrophages chemokines cytokines inflammation tumor microenvironment breast cancer
Published Date	2019-12-16
Publication Title	International Journal of Molecular Sciences
Volume	volume20
Issue	issue24
Publisher	MDPI
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 by the authors.
File Version	publisher
PubMed ID	31888216
DOI	10.3390/ijms20246342
Web of Science KeyUT	000506840100235
Related Url	isVersionOf https://doi.org/10.3390/ijms20246342

Multipotent Neurotrophic Effects of Hepatocyte Growth Factor in Spinal Cord Injury

FullText URL	fulltext.pdf
Author	Yamane, Kentaro\| Misawa, Haruo\| Takigawa, Tomoyuki\| Ito, Yoshihiro\| Ozaki, Toshifumi\| Matsukawa, Akihiro\|
Keywords	hepatocyte growth factor spinal cord injury neural regeneration
Published Date	2019-12-02
Publication Title	International Journal of Molecular Sciences
Volume	volume20
Issue	issue23
Publisher	MDPI
Start Page	6078
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 by the authors.
File Version	publisher
PubMed ID	31810304
DOI	10.3390/ijms20236078
Web of Science KeyUT	000504428300260
Related Url	isVersionOf https://doi.org/10.3390/ijms20236078

A Surgical Instructor Training Course for the Next Generation

JaLCDOI	10.18926/AMO/57956
FullText URL	74_1_73.pdf
Author	Yamane, Masaomi\| Mandai, Yasuhiro\| Ino, Hideo\| Matsukawa, Akihiro\| Toyooka, Shinichi\|
Abstract	In 2016, Gunma University Hospital’s Medical Accident Investigation Committee released a report reiterating the necessity of medical education and the need for surgeons to master non-technical skills. We designed a 17-h training course for surgical instructors, designed to teach participants how to sufficiently educate surgeon trainees and encourage their professional identity formation. A post-training survey showed that participants improved their awareness, and their behavioral changes led to favorable team performances. We then began offering a 3-h workshop focusing on the participants’ experiences. We propose that the training course using participant narratives is required and effective to establish surgeons’ self-reflection and professional identity as surgeons.
Keywords	professional identity instructor training narrative
Amo Type	Short Communication
Publication Title	Acta Medica Okayama
Published Date	2020-02
Volume	volume74
Issue	issue1
Publisher	Okayama University Medical School
Start Page	73
End Page	76
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2020 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	32099252
Web of Science KeyUT	000516606200011
NAID	120006795623

A Promising New Anti-Cancer Strategy: Iron Chelators Targeting CSCs

JaLCDOI	10.18926/AMO/57946
FullText URL	74_1_1.pdf
Author	Chen, Yuehua\| Ohara, Toshiaki\| Xing, Boyi\| Qi, Jiping\| Noma, Kazuhiro\| Matsukawa, Akihiro\|
Abstract	Iron is a trace but vital element in the human body and is necessary for a multitude of crucial processes in life. However, iron overload is known to induce carcinogenesis via oxidative stress. Cancer cells require large amounts of iron for their rapid division and cell growth. Iron was recently found to play a role in cancer stem cells (CSCs); it maintains stemness during development. Iron also plays an important role in stemness by moderating reactive oxygen species. Thus, iron metabolism in CSCs is a promising therapeutic target. In this review, we summarize the roles of iron in cancer cells and CSCs. We also summarize anti-cancer therapeutic studies with iron chelators and describe our expectation of a new therapeutic strategy for CSCs on the basis of our findings.
Keywords	cancer stem cell stemness iron chelation chemotherapy
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2020-02
Volume	volume74
Issue	issue1
Publisher	Okayama University Medical School
Start Page	1
End Page	6
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2020 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	32099242
Web of Science KeyUT	000516606200001
NAID	120006795613

Spred2 Regulates High Fat Diet-Induced Adipose Tissue Inflammation, and Metabolic Abnormalities in Mice

FullText URL	FI_10_17.pdf
Author	Ohkura, Takahiro\| Yoshimura, Teizo\| Fujisawa, Masayoshi\| Ohara, Toshiaki\| Marutani, Rie\| Usami, Kaya\| Matsukawa, Akihiro\|
Keywords	Ras/Raf/ERK/MAPK Spred2 adipocyte inflammation macrophage obesity
Published Date	2019-01-22
Publication Title	Frontiers in Immunology
Volume	volume10
Publisher	Frontiers Media S.A
Start Page	17
ISSN	1664-3224
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	Copyright © 2019 Authors
File Version	publisher
PubMed ID	30723473
DOI	10.3389/fimmu.2019.00017
Web of Science KeyUT	000456196900002
Related Url	isVersionOf https://doi.org/10.3389/fimmu.2019.00017

A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness

FullText URL	cancers_11_2_177.pdf
Author	Katsura, Yuki\| Ohara, Toshiaki\| Noma, Kazuhiro\| Ninomiya, Takayuki\| Kashima, Hajime\| Kato, Takuya\| Sato, Hiroaki\| Komoto, Satoshi\| Narusaka, Toru\| Tomono, Yasuko\| Xing, Boyi\| Chen, Yuehua\| Tazawa, Hiroshi\| Kagawa, Shunsuke\| Shirakawa, Yasuhiro\| Kasai , Tomonari\| Seno, Masaharu\| Matsukawa, Akihiro\| Fujiwara, Toshiyoshi\|
Keywords	cancer stem cells combination therapy iron stemness
Published Date	2019-02-03
Publication Title	Cancers
Volume	volume11
Issue	issue2
Publisher	MDPI
Start Page	177
ISSN	2072-6694
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 by the authors
File Version	publisher
PubMed ID	30717462
DOI	10.3390/cancers11020177
Web of Science KeyUT	000460747200051
Related Url	isVersionOf https://doi.org/10.3390/cancers11020177

The relationship between the PD-L1 expression of surgically resected and fine-needle aspiration specimens for patients with pancreatic cancer

FullText URL	JGastroenterol_54_11_1019.pdf Table.pdf Figure 1.jpg Figure 2.jpg Figure 3A.tif Figure 3B.tif supplemental figure 1.jpg
Author	Matsumoto, Kazuyuki\| Ohara, Toshiaki\| Fujisawa, Masayoshi\| Takaki, Akinobu\| Takahara, Masahiro\| Tanaka, Noriyuki\| Kato, Hironari\| Horiguchi, Shigeru\| Yoshida, Ryuichi\| Umeda, Yuzo\| Fushimi, Soichiro\| Yagi, Takahito\| Matsukawa, Akihiro\| Okada, Hiroyuki\|
Keywords	Immunohistochemistry PD-L1 Pancreatic cancer
Note	This fulltext will be available in Apr 2020\|
Published Date	2019-04-29
Publication Title	Journal of Gastroenterology
Volume	volume54
Issue	issue11
Start Page	1019
End Page	1028
ISSN	09441174
NCID	AA10988015
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	31032528
DOI	10.1007/s00535-019-01586-6
Web of Science KeyUT	000492169400008
Related Url	isVersionOf https://doi.org/10.1007/s00535-019-01586-6

Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells

Author	Yoshimura, Teizo\| Howard, O. M. Zack\| Ito, Toshihiro\| Kuwabara, Masaki\| Matsukawa, Akihiro\| Chen, Keqiang\| Liu, Ying\| Liu, Mingyong\| Oppenheim, Joost J.\| Wang, Ji Ming\|
Published Date	2013-03-18
Publication Title	PLOS ONE
Volume	volume8
Issue	issue3
Content Type	Journal Article

A novel, visible light-induced, rapidly cross-linkable gelatin scaffold for osteochondral tissue engineering

Author	Mazaki, Tetsuro\| Shiozaki, Yasuyuki\| Yamane, Kentaro\| Yoshida, Aki\| Nakamura, Mariko\| Yoshida, Yasuhiro\| Zhou, Di\| Kitajima, Takashi\| Tanaka, Masato\| Ito, Yoshihiro\| Ozaki, Toshifumi\| Matsukawa, Akihiro\|
Published Date	2014-03-25
Publication Title	Scientific Reports
Volume	volume4
Content Type	Journal Article

Enhanced in vivo osteogenesis by nanocarrier-fused bone morphogenetic protein-4

Author	Shiozaki, Yasuyuki\| Kitajima, Takashi\| Mazaki, Tetsuro\| Yoshida, Aki\| Tanaka, Masato\| Umezawa, Akihiro\| Nakamura, Mariko\| Yoshida, Yasuhiro\| Ito, Yoshihiro\| Ozaki, Toshifumi\| Matsukawa, Akihiro\|
Published Date	2013-04
Publication Title	International Journal of Nanomedicine
Volume	volume8
Issue	issue1
Content Type	Journal Article

Occult Compression Fracture of Metacarpal Head without Evidence of Avascular Necrosis

JaLCDOI	10.18926/AMO/51867
FullText URL	67_5_311.pdf
Author	Nishida, Keiichiro\| Hashizume, Hiroyuki\| Matsukawa, Akihiro\| Hashizume, Kenzo\| Shimamura, Yasunori\| Torigoe, Yasuyuki\| Ozaki, Toshifumi\|
Abstract	We report a case of 4th metacarpal head collapse of a 19-year-old healthy man. MRI revealed T1 low and T2 high regions in the collapsed 4th metacarpal head, as well as in the right 3rd and left 4th metacarpal head. Our initial diagnosis was occult compression fracture due to avascular necrosis, known as Dieterich's disease. However, pathological findings of surgically resected right 4th metacarpal head were compatible with transient osteoporosis and metacarpal head fracture followed by active tissue repair. The autologous osteochondral transplants from costchondral junction survived and maintained their size and shape even at 10-year follow-up.
Keywords	occult compression fracture metacarpal head avascular necrosis osteochondral autograft
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2013-10
Volume	volume67
Issue	issue5
Publisher	Okayama University Medical School
Start Page	311
End Page	317
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2013 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	24145731
Web of Science KeyUT	000325836100005