Okayama University Medical School Acta Medica Okayama 0386-300X 69 3 2015 Pure Choriocarcinoma of the Ovary in Silver-Russell Syndrome 183 188 EN Tomoko Haruma Chikako Ogawa Takeshi Nishida Tomoyuki Kusumoto Keiichiro Nakamura Noriko Seki Takaaki Katayama Yuji Hiramatsu Case Report 10.18926/AMO/53526 Pure ovarian choriocarcinoma is an extremely rare malignancy that can be gestational or non-gestational in origin. Silver-Russell syndrome (SRS) is a rare congenital developmental disorder characterized by pre- and postnatal growth failure, relative macrocephaly, a triangular face, hemihypotrophy, and fifth-finger clinodactyly. We report a rare case of pure ovarian choriocarcinoma occurring in a 19-year-old woman with SRS. Following surgery, multiple chemotherapy courses were effective and she was free of disease at the 10-month follow-up. No potential conflict of interest relevant to this article was reported.

岡山医学会 Acta Medica Okayama 0030-1558 126 1 2014 PET/CT SUVmaxは子宮体癌の予後不良因子になりうる 11 15 EN Keiichiro Nakamura Ikuo Joja Chikako Fukushima Tomoko Haruma Chiaki Hayashi Tomoyuki Kusumoto Noriko Seki Atsushi Hongo Yuji Hiramatsu No potential conflict of interest relevant to this article was reported.

Okayama University Medical School Acta Medica Okayama 0386-300X 67 3 2013 Three Cases of Struma Ovarii Underwent Laparoscopic Surgery with Definite Preoperative Diagnosis 191 195 EN Nurliza Binti Md Nor Tomoyuki Kusumoto Seiji Inoue Keiichiro Nakamura Noriko Seki Atsushi Hongo Junichi Kodama Yuji Hiramatsu Case Report 10.18926/AMO/50413 Struma ovarii is a rare neoplasm that accounts for approximately 0.3ｵ of ovarian tumors. Due to its ultrasound morphology, which is quite similar to that of malignant ovarian carcinoma, most struma ovarii cases are open operated with laparotomy rather than laparoscopy. We present 3 cases of struma ovarii, which were diagnosed preoperatively by imaging studies and removed by laparoscopic surgery. All patients were premenopausal women between ages 31‒50. The magnetic resonance imaging (MRI) findings were complex masses composed of multiple cysts and solid components with T2-hypointense regions as well as multiple T1-hyperintense cystic areas, findings that are typical for struma ovarii. A combination of plain computed tomography (CT), positron emission tomography (PET)-CT, and scintigraphy was useful for diagnosis. Laboratory examination revealed elevated serum thyroglobulin, which led to the diagnosis of struma ovarii. Laparoscopic surgeries were performed without rupturing the tumors. Although it has been difficult to differentiate between struma ovarii and malignant tumors by conventional methods, recently MRI techniques appear make it possible to diagnose struma ovarii preoperatively from the abovementioned imaging characteristic, together with laboratory data. As for treatment, we think laparoscopy could be successful for struma ovarii, but the surgeon must be careful not to rupture the tumor intra-abdominally in order to prevent dissemination, which could lead to malignancy. No potential conflict of interest relevant to this article was reported.