| Author | 木浦 勝行| 谷本 安| 田端 雅弘| 金廣 有彦| 上岡 博| 谷本 光音| 渡邊 都貴子| 草野 展周| 小出 典男| |
|---|---|
| Published Date | 2005-05-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume115 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Kiura, Katsuyuki| |
|---|---|
| Published Date | 2013-08-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume125 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Kiura, Katsuyuki| Tanimoto, Mitsune| |
|---|---|
| Published Date | 2013-04-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume125 |
| Issue | issue1 |
| Content Type | Journal Article |
| Title Alternative | Treatment for a non-compliant patient with cancer and epilepsy |
|---|---|
| FullText URL | 126_133.pdf |
| Author | Minami, Daisuke| Ichihara, Eiki| Okabe, Nobuyuki| Yokomichi, Naosuke| Kouge, Noriko| Kajizono, Makoto| Akimoto, Yutaka| Hori, Keisuke| Matsubara, Minoru| Nasu, Junichiro| Tanimoto, Mitsune| Kiura, Katsuyuki| Matsuoka, Junzi| |
| Abstract | A 58-year-old man with cervical esophageal cancer and a history of epilepsy was treated with chemoradiotherapy from May of 2013. When tube feeding was initiated due to aspiration pneumonitis, the patient showed a degree of irritability that affected routine staff work and treatment compliance. We attempted to perform supportive care for maladjustment by the notice, the fast, and the tube feeding, but there was no improvement. After we added carbamazepine, primidone, and propericiazine (which had been canceled at the initiation of the tube feeding) to the patient's intravenous phenytoin, the symptoms and treatment compliance improved significantly. We concluded that the causes of the patient's irritability were maladjustment and his epilepsy. |
| Keywords | てんかん（epilepsy） 易怒性（irritability） 適応障害（maladjustment） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-08-01 |
| Volume | volume126 |
| Issue | issue2 |
| Start Page | 133 |
| End Page | 135 |
| ISSN | 0030-1558 |
| language | 日本語 |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.133 |
| NAID | 130004685264 |
| Author | Ichihara, Eiki| Ohashi, Kadoaki| Takigawa, Nagio| Osawa, Masahiro| Ogino, Atsuko| Tanimoto, Mitsune| Kiura, Katsuyuki| |
|---|---|
| Published Date | 2011-04-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume123 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Taniguchi, Akihiko| Miyahara, Nobuaki| Nakahara, Atsushi| Takata, Saburo| Sakugawa, Ryo| Nagano, Osamu| Tanimoto, Yasushi| Kanehiro, Arihiko| Kiura, Katsuyuki| Ujike, Yoshito| Tanimoto, Mitsune| |
|---|---|
| Published Date | 2011-12-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume123 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Ichihara, Eiki| Matsuoka, Junji| Takigawa, Nagio| Matsuzaki, Takashi| Katsui, Kuniaki| Kiura, Katsuyuki| Tanimoto, Mitsune| |
|---|---|
| Published Date | 2009-12-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume121 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | 谷本 安| 佐久川 亮| 木浦 勝行| 谷本 光音| |
|---|---|
| Published Date | 2005-01-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume116 |
| Issue | issue3 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/61429 |
|---|---|
| FullText URL | 75_1_15.pdf |
| Author | Katsui, Kuniaki| Ogata, Takeshi| Tada, Akihiro| Sugiyama, Soichi| Yoshio, Kotaro| Kuroda, Masahiro| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Hiraki, Takao| Kanazawa, Susumu| |
| Abstract | The aim of this study was to investigate whether volumetric positron emission tomography (PET) parameters are prognostic predictors in stage III non-small cell lung cancer patients receiving definitive concurrent chemo-radiotherapy (CCRT) with cisplatin/docetaxel. Cases involving definitive CCRT were reviewed retrospectively, and the maximum standardized uptake value, metabolic tumor volume (MTV) and total lesion glycolysis (TLG) were calculated. The relationships between these PET parameters and prognosis were analyzed. MTV and TLG were significant predictors of distant metastasis-free survival (DMFS) (p = 0.0003 and 0.0005, respectively) and progression-free survival (PFS) (p = 0.001 and 0.0007, respectively). The three-year DMFS rates in patients with low and high MTV were 13.3% and 64.6%, respectively, and the corresponding values in those with low and high TLG were 13.3% and 65.2%, respectively. The three-year PFS rates in patients with low and high MTV were 13.3% and 57.8%, respectively, and the corresponding values in patients with low and high TLG were 13.3% and 57.8%, respectively. However, MTV and TLG were not predictors of local control or overall sur-vival. We demonstrated that volumetric PET parameters were predictors of patients receiving definitive CCRT. Our findings contradict the findings of previous reports and warrant further research to validate them. |
| Keywords | volumetric positron emission tomography parameters distant metastasis-free survival chemoradiotherapy cisplatin/docetaxel non-small cell lung cancer |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-02 |
| Volume | volume75 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 15 |
| End Page | 23 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33649609 |
| Author | Takeda, Hiromasa| Takigawa, Nagio| Ohashi, Kadoaki| Minami, Daisuke| Kataoka, Itaru| Ichihara, Eiki| Ochi, Nobuaki| Tanimoto, Mitsune| Kiura, Katsuyuki| |
|---|---|
| Published Date | 2013-02-15 |
| Publication Title | Experimental Cell Research |
| Volume | volume319 |
| Issue | issue4 |
| Content Type | Journal Article |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Watanabe, Hiromi| Ichihara, Eiki| Kayatani, Hiroe| Makimoto, Go| Ninomiya, Kiichiro| Nishii, Kazuya| Higo, Hisao| Ando, Chihiro| Okawa, Sachi| Nakasuka, Takamasa| Kano, Hirohisa| Hara, Naofumi| Hirabae, Atsuko| Kato, Yuka| Ninomiya, Takashi| Kubo, Toshio| Rai, Kammei| Ohashi, Kadoaki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki| |
| Published Date | 2021-01-07 |
| Publication Title | Cancer science |
| Publisher | Wiley |
| ISSN | 1347-9032 |
| NCID | AA11808050 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 33410241 |
| NAID | 120007008532 |
| DOI | 10.1111/cas.14801 |
| Web of Science KeyUT | 000630136900001 |
| Related Url | isVersionOf https://doi.org/10.1111/cas.14801 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kano, Hirohisa| Ichihara, Eiki| Harada, Daijiro| Inoue, Koji| Kayatani, Hiroe| Hosokawa, Shinobu| Kishino, Daizo| Watanabe, Kazuhiko| Ochi, Nobuaki| Oda, Naohiro| Hara, Naofumi| Ninomiya, Kiichiro| Hotta, Katsuyuki| Maeda, Yoshinobu| Kiura, Katsuyuki| |
| Keywords | immune checkpoint inhibitor non-small cell-lung cancer PD-L1 pembrolizumab poor performance status |
| Published Date | 2020-07-29 |
| Publication Title | Cancer Science |
| Volume | volume111 |
| Issue | issue10 |
| Publisher | Wiley |
| Start Page | 3739 |
| End Page | 3746 |
| ISSN | 1347-9032 |
| NCID | AA11808050 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors. |
| File Version | publisher |
| PubMed ID | 32726470 |
| DOI | 10.1111/cas.14590 |
| Web of Science KeyUT | 000562490200001 |
| Related Url | isVersionOf https://doi.org/10.1111/cas.14590 |
| JaLCDOI | 10.18926/AMO/32866 |
|---|---|
| FullText URL | fulltext.pdf |
| Author | Fujimoto, Nobukazu| Kiura, Katsuyuki| Takigawa, Nagio| Fujiwara, Yoshiro| Toyooka, Shinichi| Umemura, Shigeki| Tabata, Masahiro| Ueoka, Hiroshi| Tanimoto, Mitsune| |
| Abstract | <p>We examined the feasibility of triplet chemotherapy using cisplatin, docetaxel, and irinotecan for patients with recurrent or refractory non-small cell lung cancer (NSCLC), retrospectively. Twenty-five patients (21 men and 4 women) with NSCLC and good performance status who were <70 years old were analyzed. The median age was 58 years. Most patients had performance status 1 (16/25), stage IV disease (18/25) and adenocarcinoma-histology (16/25). Cisplatin and docetaxel were given on day 1 and irinotecan on day 2;the cycle was repeated every 3 weeks. The objective response rate was 39.1% (95% confidence interval:18.7-59.5%). The median survival time and actual 2-, 3-, and 5-year survival rates were 14.3 months, 32%, 20%, and 8%, respectively. Of note, only 6 patients were treated with gefitinib at the recurrence after triplet chemotherapy;of these, 4 (67%) achieved a partial response, which might result in favorable survival. Grade 3/4 toxicities consisted of neutropenia (100%), neutropenic fever (56%), nausea/vomiting (40%), and diarrhea (16%);no cases of treatment-related death occurred. Triplet chemotherapy showed impressive survival data in our clinical trial, but proved too toxic for use in treating patients with NSCLC in the clinical practice.</p> |
| Keywords | cisplatin docetaxel irinotecan triplet chemotherapy gefitinib |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2010-02 |
| Volume | volume64 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 33 |
| End Page | 37 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 20200582 |
| Web of Science KeyUT | 000274868300005 |
| FullText URL | fulltext20210810-3.pdf |
|---|---|
| Author | Nishii, Kazuya| Ohashi, Kadoaki| Watanabe, Hiromi| Makimoto, Go| Nakasuka, Takamasa| Higo, Hisao| Ninomiya, Kiichiro| Kato, Yuka| Kubo, Toshio| Rai, Kammei| Ichihara, Eiki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki| |
| Keywords | epidermal growth factor receptor osimertinib bevacizumab cetuximab hypoxia‑inducible factor‑1α transforming growth factor‑α |
| Published Date | 2021-7-7 |
| Publication Title | Oncology Letters |
| Volume | volume22 |
| Issue | issue3 |
| Publisher | Spandidos Publications |
| Start Page | 639 |
| ISSN | 1792-1074 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Nishii et al. This is an open access article distributed under the terms of Creative Commons Attribution License. |
| File Version | publisher |
| DOI | 10.3892/ol.2021.12900 |
| Web of Science KeyUT | 000678494600001 |
| Related Url | isVersionOf https://doi.org/10.3892/ol.2021.12900 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kitamura, Wataru| Asada, Noboru| Tabata, Tetsuya| Shibata, Rei| Nishi, Tatsuya| Kato, Yuka| Takasuka, Hiroki| Fujiwara, Hideaki| Ennishi, Daisuke| Nishimori, Hisakazu| Fujii, Nobuharu| Matsuoka, Ken-Ichi| Kiura, Katsuyuki| Yoshino, Tadashi| Maeda, Yoshinobu| |
| Keywords | marginal zone lymphoma diffuse large B-cell lymphoma anterior mediastinum cystic lesions |
| Published Date | 2022 |
| Publication Title | Journal Of Clinical And Experimental Hematopatholo |
| Volume | volume62 |
| Issue | issue1 |
| Publisher | The Japanese Society for Lymphoreticular Tissue Research |
| Start Page | 35 |
| End Page | 40 |
| ISSN | 1346-4280 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Japanese Society for Lymphoreticular Tissue Research |
| File Version | publisher |
| PubMed ID | 34840205 |
| DOI | 10.3960/jslrt.21010 |
| Web of Science KeyUT | 000766876600003 |
| Related Url | isVersionOf https://doi.org/10.3960/jslrt.21010 |
| JaLCDOI | 10.18926/AMO/47260 |
|---|---|
| FullText URL | 65_6_353.pdf |
| Author | Ichihara, Eiki| Kiura, Katsuyuki| Tanimoto, Mitsune| |
| Abstract | Angiogenesis is an essential process in tumor growth. The concept of angiogenesis, when proposed by Folksman in 1971, had a great impact on cancer research and therapy, as the survival and proliferation of cancer depend on angiogenesis, which could be a target of cancer therapy. In subsequent decades, numerous antiangiogenic agents were developed, and some of them have been applied clinically. However, angiogenesis includes a complex and multistep process that has not been sufficiently elucidated. In this review, we focus on signaling pathways related with tumor angiogenesis and several antiangiogenic agents approved by the United States Food and Drug Administration or under investigation. |
| Keywords | angiogenesis cancer |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-12 |
| Volume | volume65 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 353 |
| End Page | 362 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 22189475 |
| Web of Science KeyUT | 000298516900001 |
| FullText URL | fulltext.pdf figs.pdf tables.pdf |
|---|---|
| Author | Itano, Junko| Higo, Hisao| Ohashi, Kadoaki| Makimoto, Go| Nishii, Kazuya| Hotta, Katsuyuki| Miyahara, Nobuaki| Maeda, Yoshinobu| Kiura, Katsuyuki| |
| Keywords | osimertinib drug-induced ILD reversed halo sign organizing pneumonia pattern re-administration |
| Published Date | 2020-03-15 |
| Publication Title | Internal Medicine |
| Volume | volume59 |
| Issue | issue6 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 823 |
| End Page | 828 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | 英語 |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by The Japanese Society of Internal Medicine |
| File Version | author |
| PubMed ID | 31787696 |
| DOI | 10.2169/internalmedicine.3689-19 |
| Web of Science KeyUT | 000521137500011 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.3689-19 |
| Author | Kubo, Toshio| Takigawa, Nagio| Osawa, Masahiro| Harada, Daijiro| Ninomiya, Takashi| Ochi, Nobuaki| Ichihara, Eiki| Yamane, Hiromichi| Tanimoto, Mitsune| Kiura, Katsuyuki| |
|---|---|
| Published Date | 2013-01 |
| Publication Title | Cancer Science |
| Volume | volume104 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/54514 |
|---|---|
| FullText URL | 70_4_327.pdf |
| Author | Watanabe, Mototsugu| Yamamoto, Hiromasa| Eikawa, Shingo| Shien, Kazuhiko| Shien, Tadahiko| Soh, Junichi| Hotta, Katsuyuki| Wada, Jun| Hinotsu, Shiro| Fujiwara, Toshiyoshi| Kiura, Katsuyuki| Doihara, Hiroyoshi| Miyoshi, Shinichiro| Udono, Heiichiro| Toyooka, Shinichi| |
| Abstract | A study to evaluate the effect of metformin on the immune system was commenced in July 2014. Metformin is one of the most commonly prescribed drugs for type 2 diabetes, and previous studies have reported that metformin has an anti-tumor effect. The aim of this study is to evaluate the efficacy of metformin on the immune system in human cancer patients in vivo. The primary outcome parameter will be the rate change in the population of CD8＋ T cells, which produce multiple cytokines. |
| Keywords | metformin CD8＋ T cells cancer immunology |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 327 |
| End Page | 330 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | 英語 |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549683 |
| Web of Science KeyUT | 000384748600018 |
| Author | Ueno, Tsuyoshi| Tsukuda, Kazunori| Toyooka, Shinichi| Ando, Midori| Takaoka, Munenori| Soh, Junichi| Asano, Hiroaki| Maki, Yuho| Muraoka, Takayuki| Tanaka, Norimitsu| Shien, Kazuhiko| Furukawa, Masashi| Yamatsuji, Tomoki| Kiura, Katsuyuki| Naomoto, Yoshio| Miyoshi, Shinichiro| |
|---|---|
| Published Date | 2012-04 |
| Publication Title | Lung Cancer |
| Volume | volume76 |
| Issue | issue1 |
| Content Type | Journal Article |
