Author Nishii, Kazuya| Ohashi, Kadoaki| Watanabe, Hiromi| Makimoto, Go| Nakasuka, Takamasa| Higo, Hisao| Ninomiya, Kiichiro| Kato, Yuka| Kubo, Toshio| Rai, Kammei| Ichihara, Eiki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords epidermal growth factor receptor osimertinib bevacizumab cetuximab hypoxia‑inducible factor‑1α transforming growth factor‑α
Note This is an open access article distributed under the terms of Creative Commons Attribution License.|
Published Date 2021-7-7
Publication Title Oncology Letters
Volume volume22
Issue issue3
Publisher Spandidos Publications
Start Page 639
ISSN 1792-1074
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © Nishii et al.
File Version publisher
DOI 10.3892/ol.2021.12900
Web of Science KeyUT 000678494600001
Related Url isVersionOf https://doi.org/10.3892/ol.2021.12900
FullText URL fulltext.pdf
Author Oda, Naohiro| Tabata, Masahiro| Uno, Masatoshi| Umeda, Yuzo| Kato, Hironari| Kubo, Toshio| Senoo, Satoru| Yagi, Takahito| Fujiwara, Toshiyoshi| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords pancreas mucinous cystadenocarcinoma carboplatin paclitaxel
Published Date 2021-09-15
Publication Title Internal Medicine
Volume volume60
Issue issue18
Publisher The Japanese Society of Internal Medicine
Start Page 2967
End Page 2971
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 33814494
DOI 10.2169/internalmedicine.6730-20
Web of Science KeyUT 000697279400013
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.6730-20
FullText URL fulltext.pdf
Author Okawa, Sachi| Rai, Kammei| Fujii, Nobuharu| Gion, Yuka| Ninomiya, Kiichiro| Kato, Yuka| Taniguchi, Akihiko| Kubo, Toshio| Ichihara, Eiki| Ohashi, Kadoaki| Miyahara, Nobuaki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords EGFR IgG4-related disease marginal zone lymphoma osimertinib
Published Date 2021-09-01
Publication Title Internal Medicine
Volume volume60
Issue issue17
Publisher The Japanese Society of Internal Medicine
Start Page 2831
End Page 2837
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 33775999
DOI 10.2169/internalmedicine.6470-20
Web of Science KeyUT 000695856000020
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.6470-20
FullText URL fulltext.pdf
Author Katsui, Kuniaki| Ogata, Takeshi| Sugiyama, Soichi| Yoshio, Kotaro| Kuroda, Masahiro| Hiraki, Takao| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu|
Published Date 2021-06-04
Publication Title scientific reports
Volume volume11
Issue issue1
Publisher Nature Research
Start Page 11882
ISSN 2045-2322
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021
File Version publisher
PubMed ID 34088965
DOI 10.1038/s41598-021-91449-z
Web of Science KeyUT 000678611200010
Related Url isVersionOf https://doi.org/10.1038/s41598-021-91449-z
FullText URL fulltext.pdf
Author Watanabe, Kenta| Katsui, Kuniaki| Sugiyama, Soichiro| Yoshio, Kotaro| Kuroda, Masahiro| Hiraki, Takao| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu|
Keywords Clinical pathology Elderly Non-small cell lung carcinoma Radiosurgery Stereotactic body radiation therapy
Published Date 2021-02-23
Publication Title Radiation Oncology
Volume volume16
Issue issue1
Publisher BMC
Start Page 39
ISSN 1748-717X
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2021.
File Version publisher
PubMed ID 33622369
DOI 10.1186/s13014-021-01769-7
Web of Science KeyUT 000623175000001
Related Url isVersionOf https://doi.org/10.1186/s13014-021-01769-7
JaLCDOI 10.18926/AMO/61429
FullText URL 75_1_15.pdf
Author Katsui, Kuniaki| Ogata, Takeshi| Tada, Akihiro| Sugiyama, Soichi| Yoshio, Kotaro| Kuroda, Masahiro| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Hiraki, Takao| Kanazawa, Susumu|
Abstract The aim of this study was to investigate whether volumetric positron emission tomography (PET) parameters are prognostic predictors in stage III non-small cell lung cancer patients receiving definitive concurrent chemo-radiotherapy (CCRT) with cisplatin/docetaxel. Cases involving definitive CCRT were reviewed retrospectively, and the maximum standardized uptake value, metabolic tumor volume (MTV) and total lesion glycolysis (TLG) were calculated. The relationships between these PET parameters and prognosis were analyzed. MTV and TLG were significant predictors of distant metastasis-free survival (DMFS) (p = 0.0003 and 0.0005, respectively) and progression-free survival (PFS) (p = 0.001 and 0.0007, respectively). The three-year DMFS rates in patients with low and high MTV were 13.3% and 64.6%, respectively, and the corresponding values in those with low and high TLG were 13.3% and 65.2%, respectively. The three-year PFS rates in patients with low and high MTV were 13.3% and 57.8%, respectively, and the corresponding values in patients with low and high TLG were 13.3% and 57.8%, respectively. However, MTV and TLG were not predictors of local control or overall sur-vival. We demonstrated that volumetric PET parameters were predictors of patients receiving definitive CCRT. Our findings contradict the findings of previous reports and warrant further research to validate them.
Keywords volumetric positron emission tomography parameters distant metastasis-free survival chemoradiotherapy cisplatin/docetaxel non-small cell lung cancer
Amo Type Original Article
Published Date 2021-02
Publication Title Acta Medica Okayama
Volume volume75
Issue issue1
Publisher Okayama University Medical School
Start Page 15
End Page 23
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2021 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33649609
FullText URL fulltext.pdf
Author Harada, Daijiro| Isozaki, Hideko| Kozuki, Toshiyuki| Yokoyama, Toshihide| Yoshioka, Hiroshige| Bessho, Akihiro| Hosokawa, Shinobu| Takata, Ichiro| Takigawa, Nagio| Hotta, Katsuyuki| Kiura, Katsuyuki| Okayama Lung Cancer Study Group|
Keywords Alectinib anaplastic lymphoma kinase crizotinib drug therapy non-small cell lung carcinoma
Published Date 2021-01-20
Publication Title Thoracic Cancer
Volume volume12
Issue issue5
Publisher Wiley
Start Page 643
End Page 649
ISSN 1759-7706
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Authors.
File Version publisher
PubMed ID 33470536
DOI 10.1111/1759-7714.13825
Web of Science KeyUT 000608856400001
Related Url isVersionOf https://doi.org/10.1111/1759-7714.13825
FullText URL fulltext.pdf
Author Nishii, Kazuya| Inoue, Masaaki| Obata, Hideto| Ueda, Yutaka| Kozuki, Toshiyuki| Yamasaki, Masahiro| Moritaka, Tomonori| Awaya, Yoshikazu| Sugimoto, Keisuke| Gemba, Kenichi| Kuyama, Shoichi| Ichikawa, Hirohisa| Shibayama, Takuo| Kubota, Tetsuya| Kodani, Masahiro| Kishino, Daizo| Fujimoto, Nobukazu| Ishikawa, Nobuhisa| Tsubata, Yukari| Ishii, Tomoya| Fujitaka, Kazunori| Hotta, Katsuyuki| Kiura, Katsuyuki|
Keywords Database observational study real world data surveillance treatment
Published Date 2021-01-12
Publication Title Thoracic Cancer
Volume volume12
Issue issue5
Publisher Wiley
Start Page 725
End Page 731
ISSN 1759-7706
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
PubMed ID 33434415
DOI 10.1111/1759-7714.13789
Web of Science KeyUT 000606961500001
Related Url isVersionOf https://doi.org/10.1111/1759-7714.13789
FullText URL fulltext.pdf
Author Watanabe, Hiromi| Ichihara, Eiki| Kayatani, Hiroe| Makimoto, Go| Ninomiya, Kiichiro| Nishii, Kazuya| Higo, Hisao| Ando, Chihiro| Okawa, Sachi| Nakasuka, Takamasa| Kano, Hirohisa| Hara, Naofumi| Hirabae, Atsuko| Kato, Yuka| Ninomiya, Takashi| Kubo, Toshio| Rai, Kammei| Ohashi, Kadoaki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki|
Published Date 2021-01-07
Publication Title Cancer science
Publisher Wiley
ISSN 1347-9032
NCID AA11808050
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2021 The Authors.
File Version publisher
PubMed ID 33410241
NAID 120007008532
DOI 10.1111/cas.14801
Web of Science KeyUT 000630136900001
Related Url isVersionOf https://doi.org/10.1111/cas.14801
FullText URL fulltext.pdf
Author Nishii, Kazuya| Ohashi, Kadoaki| Tamura, Tomoki| Ninomiya, Kiichiro| Matsubara, Takehiro| Senoo, Satoru| Kano, Hirohisa| Watanabe, Hiromi| Oda, Naohiro| Makimoto, Go| Higo, Hisao| Kato, Yuka| Ninomiya, Takashi| Kubo, Toshio| Yamamoto, Hiromasa | Tomida, Shuta| Hotta, Katsuyuki| Tabata, Masahiro| Toyooka, Shinichi| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords non-small cell lung cancer epidermal growth factor receptor mutations droplet digital PCR exhaled breath condensate EGFR-TKIs
Published Date 2020-12
Publication Title Oncology Letters
Volume volume20
Issue issue6
Publisher Spandidos Publications
Start Page 393
ISSN 1792-1074
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version publisher
PubMed ID 33193853
DOI 10.3892/ol.2020.12256
Web of Science KeyUT 000595649300005
Related Url isVersionOf https://doi.org/10.3892/ol.2020.12256
JaLCDOI 10.18926/AMO/60796
FullText URL 74_5_371.pdf
Author Makimoto, Go| Ohashi, Kadoaki| Maeda, Yoshinobu| Kiura, Katsuyuki|
Abstract The prognosis of advanced non-small cell lung cancer (NSCLC) patients has improved in recent decades, especially for patients with an oncogenic driver mutation. Anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) are effective for patients with the echinoderm microtubule-associated protein-like 4-ALK fusion gene. Several ALK-TKIs have been established: the first-generation ALK-TKI, crizotinib; second-generation ALK-TKIs, alectinib and ceritinib; and third-generation ALK-TKI, lorlatinib. Some ALK-TKIs are effective for tumors that are resistant to other ALK-TKIs; however, as is known in epidermal growth factor receptormutant lung cancer, tumor resistance is inevitable. ALK-positive NSCLCs acquire resistance via various mechanisms, making it a heterogeneous disease. Therefore, it is necessary to develop next-generation treatment strategies, such as the use of next-generation ALK-TKIs for secondary mutations, or combination therapies with ALK-TKIs and other TKIs. In this review, we summarize the development and use of ALK-TKIs, prior pivotal clinical trials, and resistance mechanisms.
Keywords lung cancer anaplastic lymphoma kinase tyrosine kinase inhibitors resistance mechanism
Amo Type Review
Published Date 2020-10
Publication Title Acta Medica Okayama
Volume volume74
Issue issue5
Publisher Okayama University Medical School
Start Page 371
End Page 379
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33106692
Web of Science KeyUT 000581970100001
NAID 120006892922
JaLCDOI 10.18926/AMO/60802
FullText URL 74_5_423.pdf
Author Hirabae, Atsuko| Ichihara, Eiki| Sunami, Ryota| Ota, Moeko| Iwamoto, Yoshitaka| Maeda, Yoshinobu| Kiura, Katsuyuki|
Abstract We report a case of late-onset hyperprogressive disease after cessation of a PD-1 inhibitor. A male was diagnosed with metastatic lung adenocarcinoma with little progression for 2 months before treatment. He received pembrolizumab as a second-line treatment and was subsequently prescribed docetaxel for 3 months until a slight increase in pleural effusion. At the time of progression to docetaxel, he commenced prednisolone because of immune-system-related diarrhea. After that, his general condition rapidly worsened with severe fatigue and hypoxia. Computed tomography revealed a massive increase of pleural effusion and replacement of almost the entire liver with cancer over a period of 5 weeks.
Keywords lung cancer immune checkpoint inhibitors pembrolizumab hyperprogression
Amo Type Case Report
Published Date 2020-10
Publication Title Acta Medica Okayama
Volume volume74
Issue issue5
Publisher Okayama University Medical School
Start Page 423
End Page 425
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language 英語
Copyright Holders CopyrightⒸ 2020 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 33106698
Web of Science KeyUT 000581970100007
NAID 120006892928
FullText URL fulltext.pdf
Author Senoo, Satoru| Miyahara, Nobuaki| Taniguchi, Akihiko| Oda, Naohiro| Itano, Junko| Higo, Hisao| Hara, Naofumi| Watanabe, Hiromi| Kano, Hirohisa| Suwaki, Toshimitsu| Fuchimoto, Yasuko| Kajimoto, Kazuhiro| Ichikawa, Hirohisa| Kudo, Kenichiro| Shibayama, Takuo| Tanimoto, Yasushi| Kuyama, Shoichi| Kanehiro, Arihiko| Maeda, Yoshinobu| Kiura, Katsuyuki| Okayama Respiratory Disease Study Group (ORDSG)|
Published Date 2020-08-27
Publication Title PLoS ONE
Volume volume15
Issue issue8
Publisher Public Library of Science
Start Page e0236935
ISSN 1932-6203
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 Senoo et al.
File Version publisher
PubMed ID 32853277
DOI 10.1371/journal.pone.0236935
Web of Science KeyUT 000566948800009
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0236935
FullText URL fulltext.pdf
Author Sugiura, Hiroyuki| Nishimori, Hisakazu| Nishii, Kazuya| Toji, Tomohiro| Fujii, Keiko| Fujii, Nobuharu| Matsuoka, Ken-ichi| Nakata, Koh| Kiura, Katsuyuki| Maeda, Yoshinobu|
Keywords pulmonary alveolar proteinosis primary myelofibrosis autopsy ruxolitinib
Published Date 2020-08-15
Publication Title Internal Medicine
Volume volume59
Issue issue16
Start Page 2023
End Page 2028
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 by The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 32448830
DOI 10.2169/internalmedicine.4082-19
Web of Science KeyUT 000563078400014
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.4082-19
FullText URL fulltext.pdf
Author Kano, Hirohisa| Ichihara, Eiki| Harada, Daijiro| Inoue, Koji| Kayatani, Hiroe| Hosokawa, Shinobu| Kishino, Daizo| Watanabe, Kazuhiko| Ochi, Nobuaki| Oda, Naohiro| Hara, Naofumi| Ninomiya, Kiichiro| Hotta, Katsuyuki| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords immune checkpoint inhibitor non-small cell-lung cancer PD-L1 pembrolizumab poor performance status
Published Date 2020-07-29
Publication Title Cancer Science
Volume volume111
Issue issue10
Publisher Wiley
Start Page 3739
End Page 3746
ISSN 1347-9032
NCID AA11808050
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
PubMed ID 32726470
DOI 10.1111/cas.14590
Web of Science KeyUT 000562490200001
Related Url isVersionOf https://doi.org/10.1111/cas.14590
FullText URL fulltext.pdf
Author Katsui, Kuniaki| Ogata, Takeshi| Watanabe, Kenta| Katayama, Norihisa| Kuroda, Masahiro| Kiura, Katsuyuki| Hiraki, Takao| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu|
Keywords cisplatin docetaxel dose-volume histogram non-small cell lung cancer PACIFIC trial radiation pneumonitis
Published Date 2020-05-04
Publication Title Cancer Medicine
Publisher Wiley
ISSN 2045-7634
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 The Authors.
File Version publisher
PubMed ID 32364685
DOI 10.1002/cam4.3093
Web of Science KeyUT 000530411600001
Related Url isVersionOf https://doi.org/10.1002/cam4.3093
FullText URL fulltext.pdf figs.pdf tables.pdf
Author Itano, Junko| Higo, Hisao| Ohashi, Kadoaki| Makimoto, Go| Nishii, Kazuya| Hotta, Katsuyuki| Miyahara, Nobuaki| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords osimertinib drug-induced ILD reversed halo sign organizing pneumonia pattern re-administration
Published Date 2020-03-15
Publication Title Internal Medicine
Volume volume59
Issue issue6
Publisher The Japanese Society of Internal Medicine
Start Page 823
End Page 828
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
Copyright Holders © 2020 by The Japanese Society of Internal Medicine
File Version author
PubMed ID 31787696
DOI 10.2169/internalmedicine.3689-19
Web of Science KeyUT 000521137500011
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.3689-19
FullText URL fulltext.pdf figure.pptx
Author Higo, Hisao| Miyahara, Nobuaki| Taniguchi, Akihiko| Senoo, Satoru| Itano, Junko| Watanabe, Hiromi| Oda, Naohiro| Kayatani, Hiroe| Ichikawa, Hirohisa| Shibayama, Takuo| Kajimoto, Kazuhiro| Tanimoto, Yasushi| Kanehiro, Arihiko| Maeda, Yoshinobu| Kiura, Katsuyuki| OKAYAMA respiratory disease study group (ORDSG)|
Keywords Idiopathic pulmonary fibrosis High-resolution computed tomography Pirfenidone Forced vital capacity
Note This fulltext is available in Feb. 2021.|
Published Date 2020-02-23
Publication Title Respiratory Investigation
Volume volume58
Issue issue3
Publisher Elsevier
Start Page 185
End Page 189
ISSN 22125345
NCID AA12579673
Content Type Journal Article
language 英語
File Version author
PubMed ID 32102769
DOI 10.1016/j.resinv.2019.12.007
Web of Science KeyUT 000531841500009
Related Url isVersionOf https://doi.org/10.1016/j.resinv.2019.12.007
FullText URL fulltext.pdf
Author Sugimoto, Seiichiro| Soh, Junichi| Suzawa, Ken| Miyoshi, Kentaroh| Otani, Shinji| Yamamoto, Hiromasa| Okazaki, Mikio| Yamane, Masaomi| Oto, Takahiro| Kanazawa, Susumu| Kiura, Katsuyuki| Toyooka, Shinichi|
Keywords Lung cancer Aspergillosis Surgery Radiation Chemotherapy
Note This is a post-peer-review, pre-copyedit version of an article published in Surgery Today. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00595-020-01960-5.|
Published Date 2020-01-21
Publication Title Surgery Today
Volume volume50
Issue issue8
Publisher Springer
Start Page 863
End Page 871
ISSN 0941-1291
NCID AA10824685
Content Type Journal Article
language 英語
OAI-PMH Set 岡山大学
File Version author
PubMed ID 31965262
DOI 10.1007/s00595-020-01960-5
Web of Science KeyUT 000550244700010
Related Url isVersionOf https://doi.org/10.1007/s00595-020-01960-5
FullText URL fulltext.pdf
Author Ichihara, Eiki| Miyahara, Nobuaki| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords lung cancer interstitial pneumonia
Published Date 2020-01-15
Publication Title Internal Medicine
Volume volume59
Issue issue2
Publisher 日本内科学会
Start Page 163
End Page 167
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language 英語
Copyright Holders © 2020 by The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 31534086
NAID 130007785095
DOI 10.2169/internalmedicine.3481-19
Web of Science KeyUT 000507577600002
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.3481-19